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Preview: Brightsurf Science News :: Pancreatic Cancer News

Pancreatic Cancer Current Events and Pancreatic Cancer News from Brightsurf



Pancreatic Cancer Current Events and Pancreatic Cancer News Events, Discoveries and Articles from Brightsurf



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Primary pancreatic organoid tumor models for high-throughput phenotypic drug screening

Fri, 20 Apr 18 00:05:10 -0700

A multidisciplinary team of scientists share recent advancements in innovative in-vitro cancer biology methods for screening drug-like molecules in cancer tissue relevant models in a new report published online ahead-of-print at SLAS Discovery. Entitled Advanced Development of Primary Pancreatic Organoid Tumor Models for High-Throughput Phenotypic Drug Screening, the report can be accessed for free.



Skin cancers linked with reduced risk of Alzheimer's disease

Thu, 19 Apr 18 00:02:50 -0700

Previous studies have demonstrated a decreased risk of Alzheimer's disease (AD) in individuals with various cancers, including non-melanoma skin cancers (including squamous cell cancers and basal cell cancers).



Study examines sperm production in men with testicular cancer

Thu, 19 Apr 18 00:05:20 -0700

In a study of men with testicular cancer, increasing tumor size relative to testis size was linked with a reduced ability to produce sperm.



Bedside art therapy decreases pain and anxiety in patients with cancer

Thu, 19 Apr 18 00:05:10 -0700

A brief bedside visual art intervention (BVAI) facilitated by art educators improved mood and reduced pain and anxiety in a study of inpatients with hematological cancers.



GLUT5 fluorescent probe fingerprints cancer cells

Thu, 19 Apr 18 00:10:00 -0700

Getting the results of a cancer biopsy can take up to two weeks. What if it could happen in 10 minutes? In two new papers, a team of chemists and engineers from Michigan Technological University lay the groundwork for cancer detection and diagnostics based on a fluorescent GLUT5 probe. Documented in the new research, a cancer's type and malignancy changes the GLUT5 activity in a cell, creating a detectable 'fingerprint' of cancer.



Chip-based blood test for multiple myeloma could make bone biopsies a relic of the past

Thu, 19 Apr 18 00:11:40 -0700

A University of Kansas research effort has resulted in a low-cost, reliable blood test that uses a small plastic chip about the size of a credit card that can deliver the same diagnostic information as a bone biopsy -- but using a simple blood draw instead.



Landmark study links tumor evolution to prostate cancer severity

Thu, 19 Apr 18 00:12:40 -0700

Findings from Canadian Prostate Cancer Genome Network (CPC-GENE) researchers and their collaborators, published today in Cell, show that the aggressiveness of an individual prostate cancer can be accurately assessed by looking at how that tumor has evolved. This information can be used to determine what type and how much treatment should be given to each patient, or if any is needed at all.



Improved method of delivering anti-cancer drugs

Wed, 18 Apr 18 00:16:20 -0700

A new non-toxic method for delivering anti-cancer drugs to specific parts of the human body could mean the end of the severe and nasty side effects associated with many cancer therapies, according to researchers at Cardiff University's School of Pharmacy and Pharmaceutical Sciences.



Researchers identified a protein associated with breast cancer

Wed, 18 Apr 18 00:12:20 -0700

Researchers at UT Southwestern Medical Center have identified a protein that is strongly associated with metastatic breast cancer and that could be a target for future therapies.



Diagnosing, treating neuropathy symptoms in cancer patients not exact science

Tue, 17 Apr 18 00:07:10 -0700

Most of the roughly 15.5 million cancer survivors in the US receive chemotherapy, and roughly 65 percent develop some degree of the chemotherapy-induced nerve damage known as peripheral neuropathy.



Scientists find some human cancers to be 'evolutionary accidents'

Tue, 17 Apr 18 00:11:40 -0700

New research, published in Biological Reviews and conducted by researchers from the University of Liverpool and Escola Superior de Ciências da Saúde (Brasília, Brazil) has found some type of cancers unique to humans may be a result of evolutionary accidents.



A new, streamlined approach to diagnosing and treating bowel cancer

Tue, 17 Apr 18 00:13:50 -0700

Researchers at the South Australian Health and Medical Research Institute (SAHMRI) and the University of Adelaide have discovered a faster, more cost-effective way to determine which DNA mutations cause human bowel cancer.



Study reports possible novel method for stopping untreatable pediatric brain cancers

Tue, 17 Apr 18 00:12:40 -0700

Researchers used an experimental molecular therapy in preclinical laboratory tests to effectively treat several types of deadly pediatric brain cancer and now propose advancing the treatment to clinical testing in children. Scientists report in the journal Molecular Cancer Therapeutics testing the small molecule 6-thio-2'deoxyguanosine (6-thio-dG) in brain cancer stem cells derived from tumor cells donated by patients. Researchers also tested the treatment in humanized mouse models of pediatric brain cancer.



Top-down approach gets to the bottom of cancer

Tue, 17 Apr 18 00:15:40 -0700

By studying patient colorectal tumors, a Northwestern University research team characterizes a fully intact protein that results from a mutation of the RAS gene, the first cancer gene ever pinpointed in human cancer cells. This finding opens the door for new targets for treatment of a gene currently thought to be 'undruggable.'



FDA approves new standard of care for kidney cancer

Tue, 17 Apr 18 00:01:40 -0700

The US Food and Drug Administration granted approval to the combination of two immunotherapy drugs, ipilimumab and nivolumab, for the treatment of metastatic kidney cancer.



Global ROS1 initiative: A patient-researcher collaboration targeting ROS1 cancer

Tue, 17 Apr 18 00:04:20 -0700

CU presentation at AACR2018 describes the first research-focused group of patients organized around the genetic mutation that creates their cancer, namely changes to the gene ROS1.



For aggressive breast cancer in the brain, researchers clarify immune response

Tue, 17 Apr 18 00:04:50 -0700

In a preliminary study presented at the American Association for Cancer Research Annual Meeting 2018 in Chicago, researchers from the UNC Lineberger Comprehensive Cancer Center revealed findings for what kind of immune response the body is staging against triple negative breast cancer that has spread to the brain. They hope they can use these findings to improve patient responses to drugs that work by unleashing the immune system against cancer.



Abramson Cancer Canter studies show promise of immunotherapy combinations, including CAR T

Tue, 17 Apr 18 00:06:40 -0700

As immunotherapies continue to make up a larger share of new cancer drugs, researchers are looking for the most effective ways to use these cutting edge treatments in combination with each or with other pre-existing options. New studies from the Abramson Cancer Center are providing clues on potentially effective combinations with CAR T therapy in brain cancer as well as a novel therapeutic target in head and neck cancer, and also providing greater understanding of the mechanisms of resistance in pancreatic cancer.



Novel proteomics strategies aid cancer research
This month's issue of the journal Molecular