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Preview: Brightsurf Science News :: Lung Cancer News

Lung Cancer Current Events and Lung Cancer News from Brightsurf



Lung Cancer Current Events and Lung Cancer News Events, Discoveries and Articles from Brightsurf



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Cancer immunotherapy found safe in patients with rheumatologic diseases

Wed, 24 Jan 18 00:13:10 -0800

In the largest single-center study of patients with rheumatologic diseases who were prescribed modern cancer immunotherapy with what are called immune checkpoint inhibitors, only a minority of patients experienced a flare of their rheumatologic disease or immune-related side effects.



Scientists block the siren call of two aggressive cancers

Tue, 23 Jan 18 00:10:10 -0800

Aggressive cancers like glioblastoma and metastatic breast cancer have in common a siren call that beckons the bone marrow to send along whatever the tumors need to survive and thrive.



Updated guideline for molecular testing and targeted therapies in lung cancer

Tue, 23 Jan 18 00:03:30 -0800

A panel of leading experts in molecular pathology has issued new recommendations and updates to guidelines for molecular diagnostic testing of patients with lung cancer. They are intended to help guide the treatment of patients around the world, and help oncologists and pathologists match patients with the most effective therapies.



Leading medical organizations update lung cancer guideline

Tue, 23 Jan 18 00:08:40 -0800

Rapid advancements in the molecular diagnostic testing of lung cancer have led to new treatments and greater hope for patients battling lung cancer, the most common cause of cancer death worldwide. To ensure that clinicians stay apace and provide optimal patient care, three leading medical societies-- the College of American Pathologists (CAP), the International Association for the Study of Lung Cancer (IASLC), and the Association for Molecular Pathology (AMP)--have updated their 2013 evidence-based guideline.



New approach attacks 'undruggable' cancers from the outside in

Tue, 23 Jan 18 00:08:30 -0800

Cancer researchers have made great strides in developing targeted therapies that treat the specific genetic mutations underlying a patient's cancer. However, many of the most common cancer-causing genes are so central to cellular function throughout the body that they are essentially 'undruggable'. Now, researchers at UC San Francisco have found a way to attack one of the most common drivers of lung, colorectal, and pancreatic cancer by targeting the proteins it produces on the outside of the cell.



Cases of certain type of eyelid cancer have risen steadily over past 15 years in England

Tue, 23 Jan 18 00:09:50 -0800

New cases of a particular type of eyelid cancer (squamous cell carcinoma) have risen steadily over the past 15 years in England, reveals research published online in the British Journal of Ophthalmology.



Depressive symptoms linked to shorter survival in patients with head and neck cancer

Mon, 22 Jan 18 00:09:00 -0800

In a study of patients with head and neck cancer, even mild depressive symptoms were associated with poorer overall survival.



Developing the VTX-1 liquid biopsy system: Fast and label-free enrichment of circulating tumor cells

Mon, 22 Jan 18 00:11:20 -0800

A new article in the February 2018 issue of SLAS Technology describes a new platform that could change the way cancer is diagnosed and treated by automating the isolation of circulating tumor cells (CTCs) directly from cancer patient blood. This article provides unique insight into the development of a commercial system that has the potential to change the standard of care in cancer diagnosis and treatment.



Virus shown to be likely cause of mystery polio-like illness

Mon, 22 Jan 18 00:10:40 -0800

A major review by UNSW Sydney medical researchers has identified strong evidence that a virus called Enterovirus D68 is the cause of a mystery polio-like illness that has paralysed children in the US, Canada and Europe. The study is published in the journal Eurosurveillance.



Scientists find mechanisms to avoid telomere instability found in cancer and aging cells

Mon, 22 Jan 18 00:00:20 -0800

Researchers from Instituto de Medicina Molecular (iMM) João Lobo Antunes have found that a functional component of telomeres called TERRA has to constantly be kept in check to prevent telomeric and chromosomal instability, one of the underlying anomalies associated with cancer.



How breast cancer survivors can increase their reduced life expectancy

Mon, 22 Jan 18 00:09:20 -0800

A USC study suggests regular exercise could add to the life expectancy of breast cancer survivors because it lowers their heightened risk of cardiovascular disease, Type 2 diabetes and possibly breast cancer recurrence. 'Many people don't know the No. 1 cause of death for breast cancer survivors is heart disease, not cancer,' said Christina Dieli-Conwright, lead author of a study published in the Journal of Clinical Oncology on Jan. 22.



'Hijacker' drives cancer in some patients with high-risk neuroblastoma

Mon, 22 Jan 18 00:13:20 -0800

Researchers in Memphis and Boston have collaborated to show c-MYC is an oncogene that drives neuroblastoma in some high-risk patients; the findings help set the stage for much-needed precision medicines



Researchers find link between breast cancer and two gene mutations

Fri, 19 Jan 18 00:16:00 -0800

Individuals with Lynch syndrome, a genetic condition that has long been known to carry dramatically increased risk of colorectal cancer and uterine cancer, now also have an increased risk of breast cancer. This is the conclusion of a study in the journal Genetics in Medicine which is published by Springer Nature.



Factor that doubles the risk of death from breast cancer identified

Fri, 19 Jan 18 00:00:30 -0800

Researchers at Karolinska Institutet in Sweden have discovered that the risk of death from breast cancer is twice as high for patients with high heterogeneity of the oestrogen receptor within the same tumour as compared to patients with low heterogeneity. The study, published in The Journal of the National Cancer Institute, shows that the higher risk of death is independent of other known tumour markers and also holds true for Luminal A breast cancer.



Mortality of surgery vs. targeted radiation in early lung cancer patients

Fri, 19 Jan 18 00:01:20 -0800

Among patients older than 80 years, 3.9 percent receiving surgery passed away within the 30-day post-treatment window, compared with 0.9 percent of patients receiving focused radiation.



Hedgehog signaling proteins keep cancer stem cells alive

Fri, 19 Jan 18 00:03:10 -0800

Researchers from Charité - Universitätsmedizin Berlin have discovered that the survival of cancer stem cells is dependent on the 'Hedgehog signaling pathway'. Targeting this pathway had previously shown no effect on the growth of colorectal cancer. Now, Charité scientists have demonstrated that using different drugs to target a specific aspect of the pathway may yield better treatment outcomes for patients. Results from this research have been published in the journal Cell Reports*.



Cystic fibrosis bacterial burden begins during first years of life

Fri, 19 Jan 18 00:04:40 -0800

Cystic fibrosis shortens life by making the lungs prone to repeated bacterial infections and inflammation. UNC School of Medicine researchers have now shown for the first time that the lungs' bacterial population changes in the first few years of life as respiratory infections and inflammation set in. This research offers a way to predict the onset of lung disease in children with CF and suggests a larger role for preventive therapies, such as hypertonic saline.



Distorted view amongst smokers of when deadly damage caused by smoking will

Thu, 18 Jan 18 00:13:40 -0800

Smokers have a distorted perception on when the onset of smoking-related conditions will occur, a new study in the Journal of Cognitive Psychology reports.



How cancer metastasis happens: Researchers reveal a key mechanism

Thu, 18 Jan 18 00:02:20 -0800

Cancer metastasis, the migration of cells from a primary tumor to form distant tumors in the body, can be triggered by a chronic leakage of DNA within tumor cells, according to a team led by Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center researchers.



CancerSEEK: Generalized screening for multiple cancer types

Thu, 18 Jan 18 00:09:20 -0800

Researchers have developed a noninvasive blood test based on combined analysis of DNA and proteins that may allow earlier detection of eight common cancer types. In more than 1,000 patients, their method, dubbed CancerSEEK, detected cancer with a sensitivity of 69 to 98 percent (depending on cancer type).



Can mice really mirror humans when it comes to cancer?

Thu, 18 Jan 18 00:07:50 -0800

A new Michigan State University study is helping to answer a pressing question among scientists of just how close mice are to people when it comes to researching cancer. The findings reveal how mice can actually mimic human breast cancer tissue and its genes, even more so than previously thought, as well as other cancers including lung, oral and esophagus.



Single blood test screens for eight cancer types

Thu, 18 Jan 18 00:07:20 -0800

Johns Hopkins Kimmel Cancer Center researchers developed a single blood test that screens for eight common cancer types and helps identify the location of the cancer.



Cancer gene screening more cost effective in the general population than high-risk groups

Thu, 18 Jan 18 00:10:50 -0800

A study published in the Journal of the National Cancer Institute indicates that screening the general population for mutations in specific genes is a more cost effective way to detect people at risk and prevents more breast and ovarian cancers compared to only screening patients with a personal or family history of these diseases.



Patient-derived organoids may help personalize the treatment of gastrointestinal cancers

Wed, 17 Jan 18 00:00:40 -0800

A new BJS (British Journal of Surgery) review highlights the potential of 3-D organoid models derived from patient cells to help personalize therapy for individuals with gastrointestinal cancers.



Review examines the pros and cons of surgery to reduce the risk of cancer

Wed, 17 Jan 18 00:00:10 -0800

Genetic testing is commonplace for many inheritable cancer syndromes, and with that comes the knowledge of being a gene carrier for some patients. Many guidelines recommend that gene carriers take certain steps, such as surgery, to reduce their risk of developing cancer. A new BJS (British Journal of Surgery) review explores the quality-of-life consequences of genetic testing and risk-reducing surgery.



Novel chip-based gene expression tool analyzes RNA quickly and accurately

Wed, 17 Jan 18 00:08:00 -0800

A University of Illinois and Mayo collaboration has demonstrated a novel gene expression analysis technique that can accurately measure levels of RNA quickly and directly from a cancerous tissue sample while preserving the spatial information across the tissue -- something that conventional methods cannot do.



Dulling cancer therapy's double-edged sword

Wed, 17 Jan 18 00:08:50 -0800

Researchers have discovered a very promising new pathway to preventing tumor recurrence -- 'resolvins' could be used in complement with chemotherapy, radiation and targeted therapies to stave off the tumor-promoting effects of dead cancer cell debris.



Patients with blood cancer precursor at risk of developing cancer even after 30 years

Wed, 17 Jan 18 00:09:30 -0800

Patients with monoclonal gammopathy of undetermined significance are at risk of progressing to multiple myeloma or a related cancer -- even after 30 years of stability. These are the findings of a study by Mayo Clinic researchers published in the Wednesday, Jan. 17, issue of the New England Journal of Medicine.



New drug combination helps kickstart the immune system to fight back against cancer

Wed, 17 Jan 18 00:10:50 -0800

Scientists from King's College London have found a way to boost the immune system to help it fight back against cancer. The breakthrough involves the first ever use of a combination of chemotherapy and a drug being trialed as a treatment for neonatal jaundice, that together help kick start the body's natural defenses.



Math can predict how cancer cells evolve

Tue, 16 Jan 18 00:02:10 -0800

Applied mathematics can be a powerful tool in helping predict the genesis and evolution of different types of cancers, a study from the University of Waterloo has found.



New study offers insights on genetic indicators of COPD risk

Tue, 16 Jan 18 00:03:30 -0800

Researchers have discovered that genetic variations in the anatomy of the lungs could serve as indicators to help identify people who have low, but stable, lung function early in life, and those who are particularly at risk for chronic obstructive pulmonary disease (COPD) because of a smoke-induced decline in lung function.



More evidence of link between severe gum disease and cancer risk

Tue, 16 Jan 18 00:06:00 -0800

A new study adds to accumulating research that gum disease is associated with some cancer risk. It reports a 24 percent increase in the risk of cancer among participants with severe gum disease. The highest risk was observed in cases of lung cancer, followed by colorectal cancer.



Oral health may have an important role in cancer prevention

Tue, 16 Jan 18 00:12:30 -0800

The bacteria that cause periodontitis, a disease affecting the tissues surrounding the teeth, seems to play a part also in the onset of pancreatic cancer.



Who might benefit from immunotherapy? New study suggests possible marker

Tue, 16 Jan 18 00:05:50 -0800

New research finds that PDL-1 expressed in antigen presenting cells -- macrophages and dendritic cells found in the tumor microenvironment and in the nearby lymph nodes -- is a better indicator than PDL-1 in the tumor of who will respond to immunotherapy drugs.



NHS bowel scope uptake boosted by a fifth when patients sent reassuring reminders

Sun, 14 Jan 18 00:12:00 -0800

Bowel scope screening increased by more than a fifth (21.5 percent) when people were sent additional reminders with a leaflet that addressed common concerns, according to a new study funded by Cancer Research UK.



New epidemiological study finds no connection between cases of cancer and use of plant protection products containing glyphosate

Fri, 12 Jan 18 00:07:30 -0800

BfR Communication No. 036/2017 from 22 December 2017 Epidemiological studies are a central element of public discussion in the debate surrounding the carcinogenic potential of glyphosate. A publication that appeared in the USA in November examined whether there is a possible connection between the use of glyphosate containing plant protection products and cases of cancer among people who work in agriculture using a significantly broader data base.



Scleroderma study: Hope for a longer life for patients with rare autoimmune disorder

Fri, 12 Jan 18 00:08:40 -0800

The approach could represent the first new treatment to improve survival in patients with severe scleroderma in more than four decades.



New biomarkers for colorectal cancer

Thu, 11 Jan 18 00:04:30 -0800

Researchers from the University of Luxembourg found a new biomarker for colorectal cancer (CRC) that might improve therapy and survival rates of patients. Biomarkers are measurable biological indicators for a specific disease, such as changes in the amounts of certain proteins that occur in combination with certain illnesses. Such biomarkers help physicians to diagnose a condition, identify the disease stage, and determine a patient's risk for recurrence of the disease. This supports the doctor in choosing the best-fitting treatment plan.



Education and income determine whether women participate in cervical screening

Thu, 11 Jan 18 00:05:30 -0800

The impression that foreign-born women in Sweden more often are excluded from gynecological cancer screening needs to be reconsidered. A study from Sahlgrenska Academy, published in the journal PLOS One, makes it clear that foreign-born women participate to the same extent as women born in Sweden with a corresponding educational level and income.



NIH researchers report first 3-D structure of DHHC enzymes

Thu, 11 Jan 18 00:15:40 -0800

The first three-dimensional structure of DHHC proteins -- enzymes involved in many cellular processes, including cancer -- explains how they function and may offer a blueprint for designing therapeutic drugs.



Media Availability: The coming of age of gene therapy: A review of the past and path forward

Thu, 11 Jan 18 00:14:00 -0800

After three decades of hopes tempered by setbacks, gene therapy -- the process of treating a disease by modifying a person's DNA -- is no longer the future of medicine, but is part of the present-day clinical treatment toolkit. The Jan. 12 issue of the journal Science provides an in-depth and timely review of the key developments that have led to several successful gene therapy treatments for patients with serious medical conditions.



Researchers demonstrate RAS dimers are essential for cancer

Thu, 11 Jan 18 00:13:40 -0800

Researchers at UT Southwestern's Simmons Cancer Center have shown that RAS molecules act in pairs, known as dimers, to cause cancer, findings that could help guide them to a treatment.



Variation between strains may account for differences in vulnerability to infection

Thu, 11 Jan 18 00:00:50 -0800

New research shows that subtle differences between bacterial strains may cause dramatic differences in outcome between people infected with the same microbe.



Certain factors may predict lung cancer patients' response to chemotherapy

Wed, 10 Jan 18 00:14:20 -0800

In a retrospective analysis of 73 lung squamous cell carcinoma patients treated with the chemotherapy regimen of gemcitabine plus cisplatin, higher body mass index and younger age were linked with longer progression-free survival, the length of time that a patient lives with cancer but it does not get worse. Patients with better response to treatment and higher body mass index had longer overall survival in the Thoracic Cancer analysis.



Chemoradiation in elderly patients with stage III NSCLC improves overall survival

Wed, 10 Jan 18 00:00:40 -0800

Elderly patients with stage III non-small cell lung cancer (NSCLC) showed improved overall survival when treated with chemoradiation compared to definitive radiation alone.



New research improves our understanding of cancer cell regulation

Wed, 10 Jan 18 00:05:10 -0800

New research measures how changes in kinase activity can influence the growth, development and regulation of cancer cells. They measure kinase network rewiring that occurs in cancer patients so that they can identify new strategies for killing cancer cells.



Biomarkers may help predict outcomes in gastric cancer patients who abuse alcohol

Wed, 10 Jan 18 00:06:10 -0800

Alcohol consumption has been identified as a modifiable risk factor for cancers such as gastric cancer. A new report in the the American Journal of Pathology sheds light on how specific proteins interact with alcohol, and how that interplay impacts survival and response to platinum-based adjuvant chemotherapy in patients with gastric cancer who may or may not still be drinking.



With these special bacteria, a broccoli a day can keep the cancer doctor away

Wed, 10 Jan 18 00:08:50 -0800

NUS Medicine researchers have engineered bacteria that specifically targets colorectal cancer cells and converts a substance in some vegetables into an anticancer agent. The system reduced the number of tumors by 75 percent and shrank the remaining tumors by threefold in a mouse model of colorectal cancer. Published in Nature Biomedical Engineering, the study suggests that the probiotics taken together with a diet rich in cruciferous vegetables could help prevent colorectal cancer and its recurrence.



Salk scientists curb growth of cancer cells by blocking access to key nutrients

Wed, 10 Jan 18 00:10:40 -0800

Salk researchers have discovered how to curb the growth of cancer cells by blocking the cells' access to certain nutrients.



New prostate cancer risk score could help guide screening decisions

Wed, 10 Jan 18 00:01:10 -0800

A new score for predicting a man's genetic risk of developing aggressive prostate cancer could help guide decisions about who to screen and when, say researchers in The BMJ today.