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Preview: Brightsurf Science News :: Cancer News

Cancer Current Events and Cancer News from Brightsurf

Cancer Current Events and Cancer News Events, Discoveries and Articles from Brightsurf

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Math can predict how cancer cells evolve

Tue, 16 Jan 18 00:02:10 -0800

Applied mathematics can be a powerful tool in helping predict the genesis and evolution of different types of cancers, a study from the University of Waterloo has found.

NHS bowel scope uptake boosted by a fifth when patients sent reassuring reminders

Sun, 14 Jan 18 00:12:00 -0800

Bowel scope screening increased by more than a fifth (21.5 percent) when people were sent additional reminders with a leaflet that addressed common concerns, according to a new study funded by Cancer Research UK.

New epidemiological study finds no connection between cases of cancer and use of plant protection products containing glyphosate

Fri, 12 Jan 18 00:07:30 -0800

BfR Communication No. 036/2017 from 22 December 2017 Epidemiological studies are a central element of public discussion in the debate surrounding the carcinogenic potential of glyphosate. A publication that appeared in the USA in November examined whether there is a possible connection between the use of glyphosate containing plant protection products and cases of cancer among people who work in agriculture using a significantly broader data base.

New biomarkers for colorectal cancer

Thu, 11 Jan 18 00:04:30 -0800

Researchers from the University of Luxembourg found a new biomarker for colorectal cancer (CRC) that might improve therapy and survival rates of patients. Biomarkers are measurable biological indicators for a specific disease, such as changes in the amounts of certain proteins that occur in combination with certain illnesses. Such biomarkers help physicians to diagnose a condition, identify the disease stage, and determine a patient's risk for recurrence of the disease. This supports the doctor in choosing the best-fitting treatment plan.

Education and income determine whether women participate in cervical screening

Thu, 11 Jan 18 00:05:30 -0800

The impression that foreign-born women in Sweden more often are excluded from gynecological cancer screening needs to be reconsidered. A study from Sahlgrenska Academy, published in the journal PLOS One, makes it clear that foreign-born women participate to the same extent as women born in Sweden with a corresponding educational level and income.

Researchers demonstrate RAS dimers are essential for cancer

Thu, 11 Jan 18 00:13:40 -0800

Researchers at UT Southwestern's Simmons Cancer Center have shown that RAS molecules act in pairs, known as dimers, to cause cancer, findings that could help guide them to a treatment.

Certain factors may predict lung cancer patients' response to chemotherapy

Wed, 10 Jan 18 00:14:20 -0800

In a retrospective analysis of 73 lung squamous cell carcinoma patients treated with the chemotherapy regimen of gemcitabine plus cisplatin, higher body mass index and younger age were linked with longer progression-free survival, the length of time that a patient lives with cancer but it does not get worse. Patients with better response to treatment and higher body mass index had longer overall survival in the Thoracic Cancer analysis.

New research improves our understanding of cancer cell regulation

Wed, 10 Jan 18 00:05:10 -0800

New research measures how changes in kinase activity can influence the growth, development and regulation of cancer cells. They measure kinase network rewiring that occurs in cancer patients so that they can identify new strategies for killing cancer cells.

Biomarkers may help predict outcomes in gastric cancer patients who abuse alcohol

Wed, 10 Jan 18 00:06:10 -0800

Alcohol consumption has been identified as a modifiable risk factor for cancers such as gastric cancer. A new report in the the American Journal of Pathology sheds light on how specific proteins interact with alcohol, and how that interplay impacts survival and response to platinum-based adjuvant chemotherapy in patients with gastric cancer who may or may not still be drinking.

With these special bacteria, a broccoli a day can keep the cancer doctor away

Wed, 10 Jan 18 00:08:50 -0800

NUS Medicine researchers have engineered bacteria that specifically targets colorectal cancer cells and converts a substance in some vegetables into an anticancer agent. The system reduced the number of tumors by 75 percent and shrank the remaining tumors by threefold in a mouse model of colorectal cancer. Published in Nature Biomedical Engineering, the study suggests that the probiotics taken together with a diet rich in cruciferous vegetables could help prevent colorectal cancer and its recurrence.

Salk scientists curb growth of cancer cells by blocking access to key nutrients

Wed, 10 Jan 18 00:10:40 -0800

Salk researchers have discovered how to curb the growth of cancer cells by blocking the cells' access to certain nutrients.

New prostate cancer risk score could help guide screening decisions

Wed, 10 Jan 18 00:01:10 -0800

A new score for predicting a man's genetic risk of developing aggressive prostate cancer could help guide decisions about who to screen and when, say researchers in The BMJ today.

Targeting breast cancer through precision medicine

Tue, 09 Jan 18 00:05:20 -0800

University of Alberta researchers have discovered a mechanism that may make cancer cells more susceptible to treatment. The research team found that the protein RYBP prevents DNA repair in cancer cells, including breast cancer.

UC researchers find protein that mediates formation of HER2-driven breast cancer

Tue, 09 Jan 18 00:09:10 -0800

Researchers at the University of Cincinnati College of Medicine have identified for the first time that the estrogen receptor-binding protein MED1 is a critical mediator of HER2-driven breast cancer, identifying it as a potential therapeutic target.

Study uncovers healthcare disparities among octogenarians and nonagenarians with advanced lung cancer

Mon, 08 Jan 18 00:03:40 -0800

A new study reveals that, among patients of advanced age with stage III lung cancer, African Americans and individuals who live in lower income areas are more likely to not receive any treatment.

Landmark genetic study better predicts stomach cancer

Fri, 05 Jan 18 00:08:30 -0800

Although stomach cancer is treatable if detected early, diagnosis often occurs at an advanced stage, resulting in high mortality. A new study by researchers at the National University Health System and Duke-NUS Medical School has identified genetic patterns in intestinal metaplasia (a precondition for stomach cancer) which help predict the development of this life-threatening cancer. The discovery could enable targeted screening and earlier detection of stomach cancer, leading to better patient outcomes.

Don't give up now -- keeping your New Year's resolutions could reduce cancer risk

Thu, 04 Jan 18 00:11:00 -0800

Research published this week in ecancermedicalscience may provide the motivation needed to stick with your New Year's resolutions for healthy living. Researchers led by Professor Peter Elwood of Cardiff University, UK examined preliminary data from the UK Biobank, a prospective study of half a million subjects. They found that healthy choices may lead to a total reduction of about one-third in cancer risk.

Cancer mortality in the US continues decades-long drop

Thu, 04 Jan 18 00:11:50 -0800

The cancer death rate dropped 1.7 percent from 2014 to 2015, continuing a drop that began in 1991 and has reached 26 percent, resulting in nearly 2.4 million fewer cancer deaths during that time.

A new therapeutic target to fight metastasis in ovarian cancer

Thu, 04 Jan 18 00:13:00 -0800

Researchers of IDIBELL - ICO have described a key cellular receptor in the processes of metastasis in ovarian cancer. The finding might lead to the use of inhibitors of this receptor as a therapeutic target in the most aggressive variants of the disease.

Breast size dissatisfaction affects self-examination

Thu, 04 Jan 18 00:14:40 -0800

New research shows that women who are dissatisfied with the size of their breasts are less likely to carry out regular self-examinations to screen for breast cancer.

State-of-the-art MRI technology bypasses need for biopsy

Tue, 02 Jan 18 00:12:50 -0800

The most common type of tumor found in the kidney is generally quite small (less than 1.5 in). These tumors are usually found by accident when CAT scans are performed for other reasons and the serendipitous finding poses a problem for doctors.

Berry gives boost to cervical cancer therapy

Fri, 29 Dec 17 00:01:50 -0800

According to the Centers for Disease Control and Prevention, approximately 12,000 women in the United States are diagnosed with cervical cancer each year. One of the most common treatments for cervical cancer is radiation. While radiation therapy destroys cancer cells, it also destroys nearby healthy cells. University of Missouri School of Medicine researchers studied in vitro human cancer cells to show that combining blueberry extract with radiation can increase the treatment's effectiveness.

Cancer overrides the circadian clock to survive

Thu, 28 Dec 17 00:13:30 -0800

Tumor cells use the unfolded protein response to alter circadian rhythm, which contributes to more tumor growth, researchers at the Medical University of South Carolina (MUSC) find. A key part of the the circadian clock opposes this process, according to a report published online on December 11 in Nature Cell Biology.

New understanding of why cancer cells move

Wed, 27 Dec 17 00:11:40 -0800

A University of Hawai'i Cancer Center researcher has identified how some cancer cells are made to move during metastasis. The research provides a better understanding of how cancer spreads and may create new opportunities for cancer drug development.

Acid reflux associated with head and neck cancers in older adults

Thu, 21 Dec 17 00:02:20 -0800

Acid reflux was associated with cancer of the respiratory and upper digestive tracts in older adults.

Hunting for immune cells' cancer targets

Thu, 21 Dec 17 00:04:20 -0800

A method developed by HHMI investigators sifts through hundreds of millions of potential targets to find a precise cancer beacon. The results may lead to better immunotherapies, which harness the immune system to attack tumors.

Researchers recommend specific diets for preventing colorectal cancer in high-risk groups

Thu, 21 Dec 17 00:03:50 -0800

Researchers at the Spanish National Cancer Research Centre (CNIO) have discovered that the amount of protein in our diet may be an important factor in the prevention of colorectal cancer in different risk groups. People already suffering from inflammatory bowel disease could benefit from a high-protein diet; however, in contrast, low protein consumption may be the best option for those people who have a genetic predisposition to develop colon cancer.

Medicaid expansion leads to increase in early-stage cancer diagnoses

Thu, 21 Dec 17 00:09:40 -0800

The Affordable Care Act led to an increase in the number of cancer diagnoses -- particularly those at early stages -- in states where Medicaid was expanded, according to research from Indiana University.

G-quadruplex regulates breast cancer-associated gene

Thu, 21 Dec 17 00:10:50 -0800

For breast cancer, carrying protein CD44s, instead of CD44v, has a survival advantage. Researchers have now discovered a mechanism by which cells can regulate switching between the two proteins, opening options for the development of novel therapeutic strategies to control cancer growth in the future.

A kiss of death for prostate cancer

Thu, 21 Dec 17 00:13:40 -0800

Hokkaido University researchers have uncovered a cellular protein that stabilizes a tumor promoting signaling pathway, suggesting a new target to treat prostate cancer.

After the diagnosis: How cancer affects sexual functioning

Wed, 20 Dec 17 00:04:20 -0800

A cancer diagnosis disrupts a person's life in many ways, including sexually. A study led by the University of Houston found that more than half of young cancer patients reported problems with sexual function, with the probability of reporting sexual dysfunction increasing over time.

Fluorescent nanomedicine can guide tumor removal, kill remaining cancer cells

Wed, 20 Dec 17 00:09:10 -0800

Scientists have developed a nanomedicine platform for cancer that can help doctors know which tissue to cut out as well as kill any malignant cells that can't be surgically removed.

More tumor mutations equals higher success rate with cancer immunotherapy drugs

Wed, 20 Dec 17 00:09:30 -0800

The mutational burden, or the number of mutations present in a tumors DNA, is a good predictor of whether that cancer type will respond to a class of cancer immunotherapy drugs known as checkpoint inhibitors, a new study led by Johns Hopkins Kimmel Cancer Center researchers shows. The finding, published in the Dec. 21 New England Journal of Medicine, could be used to guide future clinical trials for these drugs.

New class of anti-cancer drug effective against kidney cancer

Wed, 20 Dec 17 00:14:10 -0800

A study published in the Journal of Clinical Oncology reports initial findings with a novel drug belonging to a new class of medicines called HIF-2a inhibitors that show promise in treating metastatic kidney cancer.

Individuals in the US diagnosed with cancer are 2.7 times more likely to declare bankruptcy than individuals without cancer, study finds

Wed, 20 Dec 17 00:05:40 -0800

As advancements in cancer therapies have been making headlines in recent years, cancer drug prices have significantly increased. The remaining question is, what are the economic impacts of the differentiations in cost of FDA approved drugs and the purchasing power of individuals around the world? This study, published in Oncotarget, titled

Novel combination therapy shown to be effective in ovarian cancer

Tue, 19 Dec 17 00:02:10 -0800

Wistar researchers have found combining PARP inhibitors, recently approved for the treatment of BRCA-mutant ovarian cancer, with another small molecule inhibitor was effective to treat ovarian cancers without BRCA1 and BRCA2 gene mutations.

Researchers find possible markers for earlier diagnosis of aggressive tongue cancer

Tue, 19 Dec 17 00:03:00 -0800

Squamous cell carcinoma of the tongue, also known as oral tongue cancer, is an aggressive form of cancer that generally affects older people. in a new study published in Oncotarget, a team of researchers has found that bacterial diversity and richness, and fungal richness, are significantly reduced in tumor tissue compared to their matched non-tumor tissues.

What factors affect quality of life in older patients with cancer?

Mon, 18 Dec 17 00:03:30 -0800

A new study provides insights on the factors that affect health-related quality of life in older adults with cancer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings support the importance of addressing persistent symptoms, managing comorbidities, promoting leisure-time physical activity, and addressing financial challenges.

Researchers repurpose immune-activating cytokine to fight breast cancer

Mon, 18 Dec 17 00:11:10 -0800

The most lethal form of breast cancer could have a new treatment option, according to new research out of the Case Comprehensive Cancer Center. In PNAS, researchers showed triple-negative breast cancer cells are highly vulnerable to interferon-β -- a potent antimicrobial that also activates the immune system. The new study shows interferon-β impairs breast cancer cells' ability to migrate and form tumors. The study also suggests interferon-β treatment could improve outcomes for certain breast cancer patients.

KAIST team develops technology to find optimum drug target for cancer

Fri, 15 Dec 17 00:12:30 -0800

A KAIST research team led by Professor Kwang-Hyun Cho of the Department of Bio and Brain Engineering developed technology to find the optimum drug target according to the type of cancer cell. The team used systems biology to analyze molecular network dynamics that reflect genetic mutations in cancer cells and to predict drug response. The technology could contribute greatly to future anti-cancer drug development.

Study prompts new ideas on cancers' origins

Fri, 15 Dec 17 00:02:20 -0800

Cancer therapies often target cells that grow and divide rapidly, such as stem cells, but in studying how stomach cancers occur, researchers at Washington University School of Medicine in St. Louis found that even when the stomach isn't able to make stem cells, other cells in the stomach can begin to divide and contribute to precancerous lesions.

New research linking cancer-inhibiting proteins to cell antennae

Thu, 14 Dec 17 00:10:10 -0800

Danish researchers have just presented a previously unknown mechanism that inhibits the ability of cells to develop into cancer cells.

Cancer immunotherapy may work better in patients with specific genes

Thu, 14 Dec 17 00:12:20 -0800

Investigators have been trying to understand why and have recently found how an individual's own genes can play a role in the response to the immunotherapy drugs.

Research letter examines firefighters and skin cancer risk

Wed, 13 Dec 17 00:11:50 -0800

This is a report of survey data collected from firefighters about skin cancer.

Even smokers may benefit from targeted lung cancer treatments

Wed, 13 Dec 17 00:13:50 -0800

No matter a patient's smoking history, when a targetable genetic alteration is present, matching the alteration with the appropriate targeted therapy is associated with a survival benefit of 1.5 years.

Malignant mitochondria as a target

Wed, 13 Dec 17 00:15:30 -0800

Killing malignant mitochondria is one of the most promising approaches in the development of new anticancer drugs. Scientists from the UK have now synthesized a copper-containing peptide that is readily taken up by mitochondria in breast cancer stem cells, where it effectively induces apoptosis. The study, which has been published in the journal Angewandte Chemie, also highlights the powerful therapeutic potential of the metallopeptides.

Medical marijuana for children with cancer? What providers think

Tue, 12 Dec 17 00:16:10 -0800

Most providers willing to consider medical marijuana use in children with cancer, but those with legal eligibility to certify are less likely to approve.

Faster, more accurate cancer detection using nanoparticles, Rutgers-led study finds

Tue, 12 Dec 17 00:08:10 -0800

Using light-emitting nanoparticles, Rutgers University-New Brunswick scientists have invented a highly effective method to detect tiny tumors and track their spread, potentially leading to earlier cancer detection and more precise treatment.

Cancer-causing mutation suppresses immune system around tumours

Tue, 12 Dec 17 00:12:10 -0800

A new study shows that mutations in 'Ras' genes, which drive 25 percent of human cancers by causing tumour cells to grow, multiply and spread, can also protect cancer cells from the immune system. The research reveals that mutated Ras genes can suppress the immune system around tumours by increasing levels of a protein called 'PD-L1'. Small amounts of PD-L1 exist naturally in the body to prevent the immune system from attacking healthy cells, but cancer cells can exploit this to protect themselves.

CCNY-led team develops cancer imaging aid from horse chestnuts

Tue, 12 Dec 17 00:13:00 -0800

Research at The City College of New York shows that cancer imaging can be simplified by a photonic process utilizing molecules derived from horse chestnuts. The study with potential to better detect the presence of cancer is led by George John, professor in City College's Division of Science, in collaboration with Jan Grimm, a physician scientist at Sloan Kettering Institute who is also affiliated with Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College.