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Preview: Brightsurf Science News :: Breast Cancer News

Breast Cancer Current Events and Breast Cancer News from Brightsurf



Breast Cancer Current Events and Breast Cancer News Events, Discoveries and Articles from Brightsurf



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Depressive symptoms linked to shorter survival in patients with head and neck cancer

Mon, 22 Jan 18 00:09:00 -0800

In a study of patients with head and neck cancer, even mild depressive symptoms were associated with poorer overall survival.



Researchers find link between breast cancer and two gene mutations

Fri, 19 Jan 18 00:16:00 -0800

Individuals with Lynch syndrome, a genetic condition that has long been known to carry dramatically increased risk of colorectal cancer and uterine cancer, now also have an increased risk of breast cancer. This is the conclusion of a study in the journal Genetics in Medicine which is published by Springer Nature.



Factor that doubles the risk of death from breast cancer identified

Fri, 19 Jan 18 00:00:30 -0800

Researchers at Karolinska Institutet in Sweden have discovered that the risk of death from breast cancer is twice as high for patients with high heterogeneity of the oestrogen receptor within the same tumour as compared to patients with low heterogeneity. The study, published in The Journal of the National Cancer Institute, shows that the higher risk of death is independent of other known tumour markers and also holds true for Luminal A breast cancer.



Hedgehog signaling proteins keep cancer stem cells alive

Fri, 19 Jan 18 00:03:10 -0800

Researchers from Charité - Universitätsmedizin Berlin have discovered that the survival of cancer stem cells is dependent on the 'Hedgehog signaling pathway'. Targeting this pathway had previously shown no effect on the growth of colorectal cancer. Now, Charité scientists have demonstrated that using different drugs to target a specific aspect of the pathway may yield better treatment outcomes for patients. Results from this research have been published in the journal Cell Reports*.



A centuries-old math equation used to solve a modern-day genetics challenge

Thu, 18 Jan 18 00:13:20 -0800

Researchers developed a new mathematical tool to validate and improve methods used by medical professionals to interpret results from clinical genetic tests. The work was published this month in Genetics in Medicine.



How cancer metastasis happens: Researchers reveal a key mechanism

Thu, 18 Jan 18 00:02:20 -0800

Cancer metastasis, the migration of cells from a primary tumor to form distant tumors in the body, can be triggered by a chronic leakage of DNA within tumor cells, according to a team led by Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center researchers.



Two new breast cancer genes emerge from lynch syndrome gene study

Thu, 18 Jan 18 00:04:00 -0800

Columbia University researchers have identified two new breast cancer genes that also cause Lynch syndrome.



CancerSEEK: Generalized screening for multiple cancer types

Thu, 18 Jan 18 00:09:20 -0800

Researchers have developed a noninvasive blood test based on combined analysis of DNA and proteins that may allow earlier detection of eight common cancer types. In more than 1,000 patients, their method, dubbed CancerSEEK, detected cancer with a sensitivity of 69 to 98 percent (depending on cancer type).



Can mice really mirror humans when it comes to cancer?

Thu, 18 Jan 18 00:07:50 -0800

A new Michigan State University study is helping to answer a pressing question among scientists of just how close mice are to people when it comes to researching cancer. The findings reveal how mice can actually mimic human breast cancer tissue and its genes, even more so than previously thought, as well as other cancers including lung, oral and esophagus.



Single blood test screens for eight cancer types

Thu, 18 Jan 18 00:07:20 -0800

Johns Hopkins Kimmel Cancer Center researchers developed a single blood test that screens for eight common cancer types and helps identify the location of the cancer.



Cancer gene screening more cost effective in the general population than high-risk groups

Thu, 18 Jan 18 00:10:50 -0800

A study published in the Journal of the National Cancer Institute indicates that screening the general population for mutations in specific genes is a more cost effective way to detect people at risk and prevents more breast and ovarian cancers compared to only screening patients with a personal or family history of these diseases.



Prebiotics in infant formula could improve learning and memory and alter brain chemistry

Wed, 17 Jan 18 00:14:40 -0800

Among other benefits, breast milk contains natural sources of prebiotics: small, indigestible fiber molecules that promote the growth of good bacteria in the baby's gut. Yet for many families, breastfeeding is difficult or impossible. Fortunately, modern infant formulas are getting closer to the real thing with the help of University of Illinois researchers.



Patient-derived organoids may help personalize the treatment of gastrointestinal cancers

Wed, 17 Jan 18 00:00:40 -0800

A new BJS (British Journal of Surgery) review highlights the potential of 3-D organoid models derived from patient cells to help personalize therapy for individuals with gastrointestinal cancers.



Review examines the pros and cons of surgery to reduce the risk of cancer

Wed, 17 Jan 18 00:00:10 -0800

Genetic testing is commonplace for many inheritable cancer syndromes, and with that comes the knowledge of being a gene carrier for some patients. Many guidelines recommend that gene carriers take certain steps, such as surgery, to reduce their risk of developing cancer. A new BJS (British Journal of Surgery) review explores the quality-of-life consequences of genetic testing and risk-reducing surgery.



Novel chip-based gene expression tool analyzes RNA quickly and accurately

Wed, 17 Jan 18 00:08:00 -0800

A University of Illinois and Mayo collaboration has demonstrated a novel gene expression analysis technique that can accurately measure levels of RNA quickly and directly from a cancerous tissue sample while preserving the spatial information across the tissue -- something that conventional methods cannot do.



Dulling cancer therapy's double-edged sword

Wed, 17 Jan 18 00:08:50 -0800

Researchers have discovered a very promising new pathway to preventing tumor recurrence -- 'resolvins' could be used in complement with chemotherapy, radiation and targeted therapies to stave off the tumor-promoting effects of dead cancer cell debris.



Mammogram rates increase after ACA eliminates co-payments

Wed, 17 Jan 18 00:09:40 -0800

A new study finds that screening mammogram rates increased after the Affordable Care Act eliminated out-of-pocket costs.



Patients with blood cancer precursor at risk of developing cancer even after 30 years

Wed, 17 Jan 18 00:09:30 -0800

Patients with monoclonal gammopathy of undetermined significance are at risk of progressing to multiple myeloma or a related cancer -- even after 30 years of stability. These are the findings of a study by Mayo Clinic researchers published in the Wednesday, Jan. 17, issue of the New England Journal of Medicine.



New drug combination helps kickstart the immune system to fight back against cancer

Wed, 17 Jan 18 00:10:50 -0800

Scientists from King's College London have found a way to boost the immune system to help it fight back against cancer. The breakthrough involves the first ever use of a combination of chemotherapy and a drug being trialed as a treatment for neonatal jaundice, that together help kick start the body's natural defenses.



Whole-population testing for breast and ovarian cancer gene mutations is cost effective

Wed, 17 Jan 18 00:10:30 -0800

Screening the entire population for breast and ovarian cancer gene mutations, as opposed to just those at high-risk of carrying this mutation, is cost effective and could prevent more ovarian and breast cancers than the current clinical approach, according to research published today in the Journal of the National Cancer Institute.



Math can predict how cancer cells evolve

Tue, 16 Jan 18 00:02:10 -0800

Applied mathematics can be a powerful tool in helping predict the genesis and evolution of different types of cancers, a study from the University of Waterloo has found.



More evidence of link between severe gum disease and cancer risk

Tue, 16 Jan 18 00:06:00 -0800

A new study adds to accumulating research that gum disease is associated with some cancer risk. It reports a 24 percent increase in the risk of cancer among participants with severe gum disease. The highest risk was observed in cases of lung cancer, followed by colorectal cancer.



Penn researchers identify new treatment target for melanoma

Tue, 16 Jan 18 00:07:20 -0800

Researchers in the Perelman School of Medicine at the University of Pennsylvania have identified a new therapeutic target for the treatment of melanoma. For decades, research has associated female sex and a history of previous pregnancy with better outcomes after a melanoma diagnosis. Now, a research team from Perelman School of Medicine at the University of Pennsylvania says it may have determined the reason for the melanoma-protective effect.



Oral health may have an important role in cancer prevention

Tue, 16 Jan 18 00:12:30 -0800

The bacteria that cause periodontitis, a disease affecting the tissues surrounding the teeth, seems to play a part also in the onset of pancreatic cancer.



Normal tissue BRCA1 methylation associated with risk for high-grade ovarian cancer

Mon, 15 Jan 18 00:01:10 -0800

Normal tissue BRCA1 methylation is associated with risk for high-grade ovarian cancer and may occur as a prenatal event. These findings are published in Annals of Internal Medicine.



Teens likely to crave junk food after watching TV ads

Mon, 15 Jan 18 00:01:20 -0800

Teenagers who watch more than three hours of commercial TV a day are more likely to eat hundreds of extra junk food snacks, according to a report by Cancer Research UK.



HKBU scholars develop new technology to decode gene transcription

Mon, 15 Jan 18 00:13:00 -0800

A research team from the School of Chinese Medicine (SCM) of Hong Kong Baptist University (HKBU) has developed the world's first model framework and 'LogicTRN' algorithm to accurately establish a gene regulatory route to analyse the genetic function and understand the biological processes.



NHS bowel scope uptake boosted by a fifth when patients sent reassuring reminders

Sun, 14 Jan 18 00:12:00 -0800

Bowel scope screening increased by more than a fifth (21.5 percent) when people were sent additional reminders with a leaflet that addressed common concerns, according to a new study funded by Cancer Research UK.



New epidemiological study finds no connection between cases of cancer and use of plant protection products containing glyphosate

Fri, 12 Jan 18 00:07:30 -0800

BfR Communication No. 036/2017 from 22 December 2017 Epidemiological studies are a central element of public discussion in the debate surrounding the carcinogenic potential of glyphosate. A publication that appeared in the USA in November examined whether there is a possible connection between the use of glyphosate containing plant protection products and cases of cancer among people who work in agriculture using a significantly broader data base.



New biomarkers for colorectal cancer

Thu, 11 Jan 18 00:04:30 -0800

Researchers from the University of Luxembourg found a new biomarker for colorectal cancer (CRC) that might improve therapy and survival rates of patients. Biomarkers are measurable biological indicators for a specific disease, such as changes in the amounts of certain proteins that occur in combination with certain illnesses. Such biomarkers help physicians to diagnose a condition, identify the disease stage, and determine a patient's risk for recurrence of the disease. This supports the doctor in choosing the best-fitting treatment plan.



Education and income determine whether women participate in cervical screening

Thu, 11 Jan 18 00:05:30 -0800

The impression that foreign-born women in Sweden more often are excluded from gynecological cancer screening needs to be reconsidered. A study from Sahlgrenska Academy, published in the journal PLOS One, makes it clear that foreign-born women participate to the same extent as women born in Sweden with a corresponding educational level and income.



Estrogen-mimicking compounds in foods may reduce effectiveness of breast cancer treatment

Thu, 11 Jan 18 00:10:10 -0800

Scientists from The Scripps Research Institute have discovered that two estrogen-mimicking compounds found in many foods appear to potently reverse the effects of palbociclib/letrozole, a popular drug combination for treating breast cancer.



NIH researchers report first 3-D structure of DHHC enzymes

Thu, 11 Jan 18 00:15:40 -0800

The first three-dimensional structure of DHHC proteins -- enzymes involved in many cellular processes, including cancer -- explains how they function and may offer a blueprint for designing therapeutic drugs.



Researchers demonstrate RAS dimers are essential for cancer

Thu, 11 Jan 18 00:13:40 -0800

Researchers at UT Southwestern's Simmons Cancer Center have shown that RAS molecules act in pairs, known as dimers, to cause cancer, findings that could help guide them to a treatment.



Certain factors may predict lung cancer patients' response to chemotherapy

Wed, 10 Jan 18 00:14:20 -0800

In a retrospective analysis of 73 lung squamous cell carcinoma patients treated with the chemotherapy regimen of gemcitabine plus cisplatin, higher body mass index and younger age were linked with longer progression-free survival, the length of time that a patient lives with cancer but it does not get worse. Patients with better response to treatment and higher body mass index had longer overall survival in the Thoracic Cancer analysis.



New research improves our understanding of cancer cell regulation

Wed, 10 Jan 18 00:05:10 -0800

New research measures how changes in kinase activity can influence the growth, development and regulation of cancer cells. They measure kinase network rewiring that occurs in cancer patients so that they can identify new strategies for killing cancer cells.



Biomarkers may help predict outcomes in gastric cancer patients who abuse alcohol

Wed, 10 Jan 18 00:06:10 -0800

Alcohol consumption has been identified as a modifiable risk factor for cancers such as gastric cancer. A new report in the the American Journal of Pathology sheds light on how specific proteins interact with alcohol, and how that interplay impacts survival and response to platinum-based adjuvant chemotherapy in patients with gastric cancer who may or may not still be drinking.



With these special bacteria, a broccoli a day can keep the cancer doctor away

Wed, 10 Jan 18 00:08:50 -0800

NUS Medicine researchers have engineered bacteria that specifically targets colorectal cancer cells and converts a substance in some vegetables into an anticancer agent. The system reduced the number of tumors by 75 percent and shrank the remaining tumors by threefold in a mouse model of colorectal cancer. Published in Nature Biomedical Engineering, the study suggests that the probiotics taken together with a diet rich in cruciferous vegetables could help prevent colorectal cancer and its recurrence.



Salk scientists curb growth of cancer cells by blocking access to key nutrients

Wed, 10 Jan 18 00:10:40 -0800

Salk researchers have discovered how to curb the growth of cancer cells by blocking the cells' access to certain nutrients.



New prostate cancer risk score could help guide screening decisions

Wed, 10 Jan 18 00:01:10 -0800

A new score for predicting a man's genetic risk of developing aggressive prostate cancer could help guide decisions about who to screen and when, say researchers in The BMJ today.



Scientists identify breast cancer patients who may develop incurable secondary cancers

Tue, 09 Jan 18 00:12:30 -0800

Scientists from King's College London, funded by Breast Cancer Now, believe they have found a way to identify lymph-node positive breast cancer patients who are most likely to develop incurable secondary tumors (metastases) and those who are less at risk. The research is published on the Jan. 9 in The Journal of Pathology: Clinical Research.



New treatments, screening methods dramatically reduce breast cancer deaths, study finds

Tue, 09 Jan 18 00:02:50 -0800

Six groups of researchers, including one from Stanford, collaborated to study the effect of advances in breast cancer screening and treatment on mortality rates.



Targeting breast cancer through precision medicine

Tue, 09 Jan 18 00:05:20 -0800

University of Alberta researchers have discovered a mechanism that may make cancer cells more susceptible to treatment. The research team found that the protein RYBP prevents DNA repair in cancer cells, including breast cancer.



UC researchers find protein that mediates formation of HER2-driven breast cancer

Tue, 09 Jan 18 00:09:10 -0800

Researchers at the University of Cincinnati College of Medicine have identified for the first time that the estrogen receptor-binding protein MED1 is a critical mediator of HER2-driven breast cancer, identifying it as a potential therapeutic target.



Female night shift workers may have increased risk of common cancers

Mon, 08 Jan 18 00:15:50 -0800

Night shift work was associated with women having an increased risk of breast, skin, and gastrointestinal cancer, according to a meta-analysis.



Study uncovers healthcare disparities among octogenarians and nonagenarians with advanced lung cancer

Mon, 08 Jan 18 00:03:40 -0800

A new study reveals that, among patients of advanced age with stage III lung cancer, African Americans and individuals who live in lower income areas are more likely to not receive any treatment.



The Academy of Breastfeeding Medicine issues guidance on informal milk sharing

Mon, 08 Jan 18 00:08:40 -0800

In response to the increasing informal sharing of human milk, the Academy of Breastfeeding Medicine (ABM) has published guidelines to minimize the risk of this practice while enhancing the health benefits.



Gene test to predict breast cancer recurrence less cost effective in real world practice
The most commonly used gene expression profile test, Oncotype DX