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Preview: Brightsurf Science News :: Virus News

Virus Current Events and Virus News from Brightsurf

Virus Current Events and Virus News Events, Discoveries and Articles from Brightsurf

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Climate change promotes the spread of mosquito and tick-borne viruses

Fri, 16 Mar 18 00:02:50 -0700

Scientists at the Joint Research Centre, the European Commission's science and knowledge service, find that global warming has allowed disease-bearing insects to proliferate, increasing exposure to viral infections.

Viral hideout

Thu, 15 Mar 18 00:00:00 -0700

The ability of the 'cold sore' herpes simplex virus to establish quiet infections and reawaken periodically has long mystified scientists. A new study in mice reveals that a key host protein acts as a critical regulator of the virus's sleep-wake cycle.

False beliefs about MMR vaccine found to influence acceptance of Zika vaccine

Thu, 15 Mar 18 00:09:10 -0700

People's willingness to use a Zika vaccine, once it's available, will be influenced by how they weigh the risks associated with the disease and the vaccine, but also by their misconceptions about other vaccines.

New model links yellow fever in Africa to climate, environment

Thu, 15 Mar 18 00:13:20 -0700

The burden of yellow fever in any given area is known to be heavily dependent on climate, particularly rainfall and temperature which can impact both mosquito life cycle and viral replication. Now, researchers from Imperial College London and the World Health Organization (WHO) have developed a new model to quantify yellow fever dynamics across Africa using not only annual averages of these climatic measures, but seasonal dynamics. Their work is described in PLOS Neglected Tropical Diseases.

Zika: An accurate estimation of the neurological risks in unborn children

Wed, 14 Mar 18 00:13:30 -0700

Thanks to a study conducted in pregnant women and their unborn children during the Zika epidemic in the French territories in the Americas, researchers from Inserm, Institut Pasteur and the University Hospital of Guadeloupe have been able to accurately estimate the risk of severe neurological complications in babies. They have also determined that the first trimester of pregnancy is the period which presents the highest risk. This research has been published in NEJM.

Researchers identify key step in viral replication

Mon, 12 Mar 18 00:04:50 -0700

Pitt and UPMC researchers showed how a common virus hijacks a host cell's protein to assemble new viruses.

Mutating Ebola's key protein may stop replication

Mon, 12 Mar 18 00:09:40 -0700

Researchers were able to mutate Viral Protein 40 (VP40) in a way that changed the residues of the protein, blocking the budding and replication of Ebola virus in a model system.

ZMapp antibody delivered by viral vector protects against Ebola infection

Fri, 09 Mar 18 00:13:30 -0800

A new study comparing the effectiveness of individual ZMapp antibodies versus a cocktail of antibodies, administered to mice using recombinant adeno-associated virus (rAAV) delivery vectors, showed the ability to achieve 100% protection against infection by Ebola virus.

Antigen study supports new approach to vaccine for respiratory syncytial virus

Fri, 09 Mar 18 00:00:20 -0800

Medical researchers have been trying to develop a vaccine for respiratory syncytial virus (RSV) for more than 50 years, without success. New findings by researchers at UC Santa Cruz, however, point to a promising route for designing an effective vaccine.

Icelandic program seeks to eliminate HCV

Wed, 07 Mar 18 00:03:30 -0800

A new Journal of Internal Medicine study describes an innovative program to eliminate hepatitis C virus (HCV) as a public health threat in Iceland.

Discovery fills gap in search for better treatments for Ebola, other viruses

Wed, 07 Mar 18 00:12:20 -0800

University of Alberta researchers have found the Ebola polymerase (enzyme), which may lead to more effective research and better treatments for the often fatal infection, and other related viral diseases.

UC Davis researchers find new way to defeat HIV latency

Wed, 07 Mar 18 00:09:10 -0800

Researchers at UC Davis Health, together with colleagues at UC San Francisco and the University of North Carolina at Chapel Hill, have found a mechanism for making HIV come out of hiding and become susceptible to anti-HIV drugs. Their study is published in The Journal of Clinical Investigation.

New test extends window for accurate detection of zika

Tue, 06 Mar 18 00:00:10 -0800

Diagnosis of Zika infection is complex. Molecular tests for exposure are only reliable in the first two to three weeks after infection. Antibody tests are confounded by cross-reactivity of antibodies to Zika with similar viruses like dengue and yellow fever. A new blood test called ZIKV-NS2B-concat ELISA is faster, less expensive, and extends the window of accurate detection to months after onset of infection, giving clinicians a powerful tool to screen for Zika throughout pregnancy.

University of Guelph researchers reveal new way to potentially fight Ebola

Tue, 06 Mar 18 00:12:20 -0800

University of Guelph researchers have shown an innovative antibody delivery method could be an effective way to prevent and treat Ebola infection. They proved that delivering a monoclonal antibody gene to a cell through a viral vector -- a process that bypasses the need for the host to generate a natural immune response -- provided up to 100-per-cent protection against infection in mice. The mice expressed the antibody for more than 300 days.

Broad spectrum antiviral drug inhibits a range of emerging coronaviruses

Tue, 06 Mar 18 00:14:40 -0800

Researchers have long known that RNA viruses called coronaviruses cause the common cold and pneumonia. In the last two decades or so, though, researchers have found that these viruses can jump between animal and human hosts. In recent years, coronaviruses have caused lethal outbreaks of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) that span multiple continents. To date, no retroviral drug has been approved to treat these infections.

Mosquito gut may hold the key to preventing Dengue and Zika

Tue, 06 Mar 18 00:14:50 -0800

A mosquito's ability to replicate and transmit a virus depends on the metabolic environment of tissues in its midgut: the primary site of infection. By targeting the sphingolipid pathway, which links together several pathways important for cell signaling and subcellular structure that are altered by virus infection, researchers could devise strategies that stall viral replication in the mosquito and prevent its transmission to humans.

Linking virus sensing with gene expression, a plant immune system course-corrects

Tue, 06 Mar 18 00:00:20 -0800

Researchers at Durham University in the UK have identified a crucial link in the process of how plants regulate their antiviral responses. The research is published in the March 2 issue of the Journal of Biological Chemistry.

Social status influences infection risk and disease-induced mortality

Tue, 06 Mar 18 00:02:30 -0800

Spotted hyena cubs of high-ranking mothers have a lower probability of infection with and are more likely to die from canine distemper virus than cubs of low-ranking mothers. In subadults and adults, the picture is reversed -- high-ranking females exhibit a higher infection probability than low-ranking females whereas mortality was similar for both groups. These are the results of a long-term study conducted by scientists at the German Leibniz Institute for Zoo and Wildlife Research.

Why the latest shingles vaccine is more than 90 percent effective

Tue, 06 Mar 18 00:07:10 -0800

A new study has shown how the body's immune system responds to the new shingles vaccine, Shingrix, making it more than 90 percent effective at protecting against the virus.

Broadly neutralizing antibody treatment may target viral reservoir in monkeys

Sun, 04 Mar 18 00:12:00 -0800

After receiving a course of antiretroviral therapy for their HIV-like infection, half of a group of monkeys infused with a broadly neutralizing antibody to HIV paired with an immune stimulatory compound suppressed the virus for over 4 months without additional treatment, according to NIAID-supported scientists. The therapy may have targeted the viral reservoir. The addition of the immune stimulatory compound appears to have extended the duration and amount of viral suppression.

How reliable is diagnostic testing for Zika?

Thu, 01 Mar 18 00:08:00 -0800

Molecular diagnostic tests for the Zika virus in Brazil are not always reliable.

MSU researchers reveal findings about virus that lives in Yellowstone hot springs

Thu, 01 Mar 18 00:14:00 -0800

Rebecca Hochstein, who earned her doctorate in MSU's Department of Microbiology and Immunology in 2015, is lead author of a study that explains how a lemon-shaped virus assembles itself and how the virus ejects the DNA it carries into host cells.

New insights into how a virus-blocking bacterium operates in mosquitos

Thu, 01 Mar 18 00:00:10 -0800

New research reveals details of the mechanism by which the bacterium Wolbachia blocks viruses in mosquito cells, suggesting that it reduces viral replication inside cells and that rapid degradation of viral RNA is involved. Professor Scott O'Neill, Program Director of the World Mosquito Program, led by Australia's Monash University, and colleagues report their findings in PLOS Pathogens.

Yellow fever virus is detected in urine and semen almost a month after infection

Thu, 01 Mar 18 00:14:40 -0800

The confirmation involved one single patient; Brazilian investigators say it suggests the virus may be contagious for a period which stretches longer than previously thought. Scientists especulate whether the use of urine samples could allow for positive diagnosis in asymptomatic patients, who comprise half of the cases of yellow fever's infection.

Here's how viruses inactivate the immune system, causing cancer

Thu, 01 Mar 18 00:05:30 -0800

'The same mechanisms that viruses use to cause cancer may be key in combating tumors with immune-based therapies or in keeping cancer from developing in the first place,' says Sharon Kuss-Duerkop, PhD.

Planning for smallpox outbreak must consider immunosuppression

Thu, 01 Mar 18 00:11:00 -0800

New research from UNSW Sydney reveals that the number of people living with weakened immune systems must be examined when planning for the real risk of smallpox re-emerging in the world. The research poses a warning after Canadian scientists last year created a smallpox-like virus in a lab using just mail order DNA.

Massive data analysis shows what drives the spread of flu in the US

Tue, 27 Feb 18 00:13:40 -0800

Using several large datasets describing health care visits, geographic movements and demographics of more than 150 million people over nine years, researchers at the University of Chicago have created models that predict the spread of influenza throughout the United States each year.

Powerful new imaging method reveals in detail how particles move in solution

Tue, 27 Feb 18 00:04:50 -0800

New research published in Nature Methods will dramatically improve how scientists 'see inside' molecular structures in solution, allowing for much more precise ways to image data in various fields, from astronomy to drug discovery.

Children's Colorado doctors conclude EV-D68 likely cause of acute flaccid myelitis

Mon, 26 Feb 18 00:12:00 -0800

A team of doctors and scientists from the US and Europe led by Kevin Messacar, MD, an infectious disease specialist from Children's Hospital Colorado (Children's Colorado), has found that Enterovirus D68 (EV-D68) is a likely cause of Acute Flaccid Myelitis (AFM), a rare illness that affects the nervous system of children. The research was published late Friday, Feb. 23 in The Lancet Infectious Diseases.

Genetics makes Asians and Europeans susceptible to severe dengue

Fri, 23 Feb 18 00:03:30 -0800

As globalization and climate change spread tropical infectious diseases around the globe, not all populations have the same degree of susceptibility. Researchers from the Institut Pasteur, CNRS and the Institute for Research and Innovation in Health-University of Porto (i3S) identified gene variants common in people of Asian and European ancestry, making them more prone than those of African origin to developing severe dengue, which can lead to potentially fatal dengue shock syndrome.

The Australian government's plan for the biocontrol of the common carp presents several risks

Thu, 22 Feb 18 00:09:00 -0800

Belgian, English and Australian scientists are calling on the Australian authorities to review their decision to introduce the carp herpes virus as a way to combat the common carp having colonised the country's rivers. In a letter published in the journal Science, they not only believe that this measure will be ineffective but that it also represents a risk to ecosystems.

NYU researchers adapt HIV test in developing rapid diagnostic test for Zika virus

Thu, 22 Feb 18 00:14:40 -0800

Researchers at New York University College of Dentistry, in collaboration with Rheonix, Inc., are developing a novel test for Zika virus that uses saliva to identify diagnostic markers of the virus in a fraction of the time of current commercial tests.

Mutation explains why some people are more vulnerable to viral brain infection

Thu, 22 Feb 18 00:15:30 -0800

Scientists identified mutations in a single gene that impair immunity to viruses in a region of the brain called the brain stem.

Researchers bring high res magnetic resonance imaging to nanometer scale

Wed, 21 Feb 18 00:16:10 -0800

A new technique that brings magnetic resonance imaging to the nanometer scale with unprecedented resolution will open the door for major advances in understanding new materials, virus particles and proteins that cause diseases like Parkinson's and Alzheimer's.

Zika virus could help combat brain cancer

Wed, 21 Feb 18 00:00:20 -0800

Study by Brazilian researchers shows infection by Zika caused death of cells from glioblastoma, the most common and aggressive kind of malignant brain tumor in adults. Scientists foresee the use of genetic engineering to neutralize Zika virus' infectious whilst preserving the viral particles which induce the death of tumoral cells.

Past encounters with the flu shape vaccine response

Tue, 20 Feb 18 00:12:50 -0800

Researchers from the University of Chicago, Harvard University and others show that poor immune responses, not egg adaptions, may explain the low effectiveness of the vaccine that year.

Infection site affects how a virus spreads through the body

Mon, 19 Feb 18 00:04:40 -0800

A person is more likely to get infected by HIV through anal intercourse than vaginal, but no one knows quite why. A new study by scientists at the Gladstone Institutes shows that infection sites could affect the immune system's response to a virus and the way the virus spreads through the body.

First multiplex test for tick-borne diseases

Fri, 16 Feb 18 00:13:40 -0800

A new blood test called the Tick-Borne Disease Serochip (TBD Serochip) promises to revolutionize the diagnosis of tick-borne disease by offering a single test to identify and distinguish between Borrelia burgdorferi, the pathogen responsible for Lyme disease, and seven other tick-borne pathogens. Led by scientists at the Center for Infection and Immunity (CII) at Columbia University's Mailman School of Public Health, the research team report details on the new test in the journal Nature: Scientific Reports.

Gene taxi with turbo drive

Thu, 15 Feb 18 00:16:30 -0800

Scientists at the German Primate Center improve DNA transfer in gene therapy.

Antioxidant treatment prevents sexual transmission of Zika in mice

Thu, 15 Feb 18 00:09:50 -0800

The antioxidant drug ebselen can prevent sexual transmission of Zika virus from male to female mice, according to new research published in PLOS Pathogens by Yogy Simanjuntak and colleagues at Academia Sinica, Taipei, Taiwan. The results hint at a potential role for ebselen in preventing Zika spread among humans.

Biochemical networks mapped in midgut of Aedes aegypti mosquitoes

Thu, 15 Feb 18 00:08:30 -0800

Scientists have mapped for the first time the midgut metabolites of the Aedes aegypti, the mosquito that can transmit viruses that cause dengue, Zika, chikungunya and yellow fever to humans.

Organ-on-chip technology enters next stage as experts test hepatitis B virus

Wed, 14 Feb 18 00:15:40 -0800

Scientists at Imperial College London have become the first in the world to test how pathogens interact with artificial human organs.

A new class of drug to treat herpes simplex virus-1 infection

Wed, 14 Feb 18 00:08:30 -0800

Researchers at the University of Illinois at Chicago have now identified a small drug molecule that can clear the HSV-1 infection in the cells of the cornea -- the clear outer layer of the eyeball -- and works completely differently than the currently-available drugs, making it a promising potential option for patients who have developed resistance.

Understanding how the body builds immunity, to build better influenza vaccines

Wed, 14 Feb 18 00:08:20 -0800

Scientists are now equipped with a more detailed picture of the human immune system's response to influenza vaccination, thanks to the results of a new investigation.

Cancer-killing virus acts by alerting immune system

Tue, 13 Feb 18 00:08:20 -0800

A new UC San Francisco study has shown that a cancer-killing ('oncolytic') virus currently in clinical trials may function as a cancer vaccine - in addition to killing some cancer cells directly, the virus alerts the immune system to the presence of a tumor, triggering a powerful, widespread immune response that kills cancer cells far outside the virus-infected region.

Smart bomb virus shows promise as brain tumor immunotherapy

Mon, 12 Feb 18 00:09:30 -0800

A common cold virus engineered to attack the most common and deadly of brain tumors allowed 20 percent of patients with recurrent glioblastoma to live for three years or longer, researchers from The University of Texas MD Anderson Cancer Center report on a phase I clinical trial in the Journal of Clinical Oncology.

Special UV light safely kills airborne flu virus, finds study

Fri, 09 Feb 18 00:00:40 -0800

Overhead far-UVC light, a type of ultraviolet light that is harmless to humans, effectively killed airborne flu virus, found researchers at Columbia University. The lighting may offer a new weapon against the spread of flu virus in public spaces.

Chicken pox vaccine linked with shingles at the vaccination site in some children

Fri, 09 Feb 18 00:04:20 -0800

New research in Pediatric Dermatology reports several cases of shingles that developed at the original vaccination site in healthy children after they were immunized against chicken pox.

Compounds isolated from rattlesnake venom show activity against hepatitis C virus

Thu, 08 Feb 18 00:02:00 -0800

Studies conducted by Brazilian researchers and published in PLOS ONE and Scientific Reports also found compounds derived from Brazilian plants to be promising against hepatitis C. In spite of the virus' resistance, tests yielded a sharp decline in viral activities such as reproduction and cell invasion.

Ebola virus infects reproductive organs in monkeys

Thu, 08 Feb 18 00:03:30 -0800

Ebola virus can infect reproductive organs of male and female macaques, according to a new study, suggesting humans could be similarly infected. Prior studies have revealed sexual transmission of Ebola virus, and viral RNA persisting in semen following recovery. While little is known about viral persistence in female reproductive tissues, pregnant women with Ebola virus disease have a maternal death rate of more than 80 percent and a fetal death rate of nearly 100 percent.