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Survival Current Events and Survival News from Brightsurf



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ALEX study shows alectinib 600 mg more effective than crizotinib in Asian cancer patients

Fri, 17 Nov 17 00:10:00 -0800

A subanalysis of the phase III ALEX study has shown that alectinib 600 mg twice daily is more effective than standard of care crizotinib in Asian patients with anaplastic lymphoma kinase (ALK) positive non-small-cell lung cancer (NSCLC), researchers report at the ESMO Asia 2017 Congress.



When to fish: Timing matters for fish that migrate to reproduce

Fri, 17 Nov 17 00:12:50 -0800

A new University of Washington study points to yet another human factor that is hampering the ability of fish to reproduce: the timing of our fishing seasons. The study considers how the timing of fishing efforts might disproportionately target certain fish and change the life history patterns of entire populations.



Quality of care for older Texas patients with colon cancer on the rise, still room for improvement

Wed, 15 Nov 17 00:01:30 -0800

Research from The University of Texas MD Anderson Cancer Center finds adherence to surgical treatment guidelines has improved significantly among older Texas patients with colon cancer since 2001, while adherence to chemotherapy guidelines has remained largely unchanged. The study, published today in Cancer, identifies factors influencing adherence rates, including socioeconomic status and access to skilled physicians.



Insurance linked to black-white survival disparities in colorectal cancer

Tue, 14 Nov 17 00:11:50 -0800

Health insurance coverage differences account for nearly one-half of the black-white survival disparity in colorectal cancer patients, according to a new study.



Study: Process used to select lung transplant patients may need to be changed

Tue, 14 Nov 17 00:10:10 -0800

New research from the University of Maryland School of Medicine suggests that the system for choosing transplant recipients in chronic obstructive pulmonary disease (COPD) may underestimate how long a person might survive without a lung transplant and therefore, may mislead clinicians.



The first effective therapy against glioblastoma by attacking telomeres

Mon, 13 Nov 17 00:03:00 -0800

Researchers at the Spanish National Cancer Research Centre (CNIO) have shown that it is possible to block the growth of human and murine glioblastoma in mouse models by blocking the TRF1 protein; an essential component of the telomere-protective complex. The study, published in Cancer Cell, describes a new and promising way to combat this type of brain tumor by attacking its ability to regenerate and divide immortally.



Heart's pumping function is not an indicator of heart failure survival rates

Sun, 12 Nov 17 00:00:20 -0800

Contrary to popular practice, a measure of the heart's pumping function known as 'left ventricular ejection fraction' is not associated with the long-term outcomes of hospitalized heart failure patients, a UCLA-led study of Medicare patients has found. Hospitalized heart failure patients in all age groups within the study and with all levels of ejection fraction had significantly lower rates of survival after five years and a higher risk of re-hospitalization than people in the United States without heart failure.



Patients with depression and advanced cancer survive longer with palliative care intervention

Fri, 10 Nov 17 00:13:40 -0800

A new Dartmouth-led study finds that patients with depression and advanced cancer live longer when exposed to palliative care interventions designed to improve quality of life.



Study led by MIT Portugal faculty and alumni finds how to increase the survival time of stem cells

Thu, 09 Nov 17 00:12:00 -0800

A team of researchers from the Faculty of Medicine at the University of Coimbra, led by Dr. Lino Ferreira, MIT Portugal Program Faculty and researcher at the Center for Neuroscience and Cell Biology (CNC) in collaboration with Langer Lab at MIT (USA), has developed a new technology, which is promising to understand and treat ischemic diseases.



Not all milkweed is equal for egg-laying monarchs, U of G study reveals

Thu, 09 Nov 17 00:14:30 -0800

Milkweed plants in agricultural areas have 3 1/2 times more monarch butterfly eggs than milkweed growing in urban gardens, natural areas and roadsides, according to a new University of Guelph study. The researchers also found monarchs prefer small patches of the plant to larger ones. These findings have implications for current initiatives underway that involve planting milkweed to help the survival of this endangered butterfly.



Older donor lungs should be considered for transplantation

Thu, 09 Nov 17 00:16:10 -0800

With a scarcity of lungs available for transplantation, the use of lungs from donors older than age 60 has been shown to achieve reasonable outcomes and should be considered as a viable option, according to research published online today in The Annals of Thoracic Surgery.



Study reveals large disparities in survival for patients with HPV-associated cancers

Mon, 06 Nov 17 00:15:50 -0800

A new study found large disparities by sex, race, and age in survival for patients diagnosed with different cancers caused by the human papillomavirus (HPV).



How caries-causing bacteria can survive in dental plaque

Thu, 02 Nov 17 00:16:00 -0700

Extracellular polysaccharides play a central role in the survival capabilities of caries-causing bacteria in dental plaque, report researchers from the University of Basel's Preventative Dentistry and Oral Microbiology Clinic and Department of Biomedical Engineering in the journal Plos One.



Onalespib could be an effective treatment for glioblastoma, preclinical studies show

Thu, 02 Nov 17 00:02:10 -0700

This study showed that the targeted drug onalespib reduced the expression of cell-survival proteins such as AKT and endothelial growth factor receptor in glioma cell lines and glioma stem cells from patient tumors. This, in turn, reduced the survival, proliferation, invasion and migration of the cells. In animal models of glioblastoma the agent crossed the blood-brain barrier and showed effectiveness as a single agent and greater effectiveness in combination with temozolomide.



Unveiling gut microbes' influence on cancer patient response to immunotherapy

Thu, 02 Nov 17 00:11:40 -0700

Two new studies in cancer patients demonstrate how the composition of gut bacteria can influence response to immunotherapy. Antibiotics, one study showed, render such treatments less effective.



Scientists link pancreatic cancer survival to four genes

Thu, 02 Nov 17 00:13:30 -0700

Alterations in four main genes are responsible for how long patients survive with pancreatic cancer, according to a new study in Jama Oncology.



Ensuring the survival of elephants in Laos: A matter of economics

Wed, 01 Nov 17 00:12:10 -0700

Asian elephant populations in Laos, which are under a process of commodification, have dropped by half in the last 30 years. According to researchers from CNRS and Beauval Nature, the dynamics of elephant populations depend heavily on the socioeconomic practices of the country and elephant owners. The setting-up of a 'maternity leave' system to compensate owners for their losses of income during breeding period would contribute to the species' long-term survival.



Experts call for virtual European cancer institute/infrastructure

Tue, 31 Oct 17 00:15:10 -0700

A new article that addresses the challenges of cancer proposes combining innovative prevention and treatment strategies in a state-of-the-art virtual European Cancer Institute/Infrastructure that promotes sharing of the highest standards of practices and big data among countries and centers across Europe and beyond.



Orphaned elephants' social lives substantially altered by poaching

Tue, 31 Oct 17 00:03:20 -0700

Colorado State University researchers found that orphaned elephants have less access to mature, dominant individuals than non-orphaned elephants, whose dominant social partners are their mothers and aunts.



Cancer trial led by University of Minnesota Medical School's Dr. Clark Chen shows promise

Fri, 27 Oct 17 00:07:30 -0700

New data from a Phase I clinical trial led by Clark Chen, M.D., Ph.D., Lyle French Chair in Neurosurgery and Head of the University of Minnesota Medical School Department of Neurosurgery shows more than a quarter of patients with recurrent high-grade glioma, a form of brain cancer, were alive more than three years after treatment.



Kidney transplantation may prolong the survival of patients on long-term dialysis

Thu, 26 Oct 17 00:13:10 -0700

In a recent analysis of individuals on dialysis for at least 10 years, those who then received a kidney transplant lived longer than those who stayed on dialysis. Transplant recipients were at higher risk of death for 180 days after transplantation, however, and they did not derive survival benefit until 657 days after transplantation.



Translocated hawks thrive in Hispaniola

Wed, 25 Oct 17 00:09:00 -0700

Species translocation -- capturing animals in one place and releasing them in another -- is a widely used conservation method for establishing or reestablishing populations of threatened species. However, translocation projects often fail when the transplanted animals fail to thrive in their new home. A new study demonstrates how close monitoring of the animals being released into a new area is helping wildlife managers gauge the success of their effort to save the Ridgway's hawk of Hispaniola.



Proton therapy for prostate cancer is advantageous to imrt according to new study

Wed, 25 Oct 17 00:10:50 -0700

Proton therapy treatment for prostate cancer is associated with higher survival rates and decreased risk of complications compared to intensity-modulated radiation therapy (IMRT) according to a new study by researchers at the Northwestern Medicine Chicago Proton Center.



Prehospital blood transfusion among combat casualties associated with improved survival

Tue, 24 Oct 17 00:16:10 -0700

Among medically evacuated US military combat causalities in Afghanistan, blood product transfusion within minutes of injury or prior to hospitalization was associated with greater 24-hour and 30-day survival than delayed or no transfusion, according to a study published by JAMA.



Weak social ties a killer for male whales

Tue, 24 Oct 17 00:07:20 -0700

Male killer whales are more likely to die if they are not at the center of their social group, new research suggests.



Novel therapies for multidrug-resistant bacteria

Mon, 23 Oct 17 00:06:40 -0700

Scientists at the University of Surrey in collaboration with research partners at the University of Sheffield and University of Würzburg, Germany, have developed novel antimicrobials, which could be used to treat infections, caused by multidrug-resistant bacteria.



Canada geese give hunters the slip by hiding out in Chicago

Mon, 23 Oct 17 00:15:50 -0700

It's open season for Canada geese in Illinois from mid-October to mid-January. Unfortunately for hunters, Canada geese are finding a new way to stay out of the line of fire. Rather than being 'sitting ducks' in a rural pond, they're setting up residence in the city. University of Illinois ornithologist Mike Ward says he and a team of researchers conducted a recent study to try to find out why there were so many Canada geese in Chicago in the winter.



Older Neandertal survived with a little help from his friends

Mon, 23 Oct 17 00:06:00 -0700

An older Neandertal from about 50,000 years ago, who had suffered multiple injuries and other degenerations, became deaf and must have relied on the help of others to avoid prey and survive well into his 40s, indicates a new analysis published Oct. 20 in the online journal PLoS ONE.



Early data shows nearly 2x prolonged median survival for inoperable pancreatic cancer

Thu, 19 Oct 17 00:10:00 -0700

A retrospective review of 42 inoperable, locally-advanced pancreatic cancer patients treated at four institutions found that higher delivered radiation doses enabled via ViewRay's MRIdian adaptive MR-guided radiation therapy showed a near doubling of median overall survival (27.8 months compared to 14.8 months) and resulted in favorably lower toxicities (0 percent compared to 15.8 percent grade 3 or higher toxicity).



Declining baby songbirds need forests to survive drought

Wed, 18 Oct 17 00:16:00 -0700

A team of Smithsonian biologists led by Brandt Ryder worked closely with Ben Vernasco, a doctoral candidate in biology at Virginia Tech, on a study that aimed to identify characteristics that promote healthy wood thrush populations on US Department of Defense land.



Cleveland clinic study: Timing of melanoma diagnosis, treatment critical to survival

Tue, 17 Oct 17 00:00:40 -0700

A new Cleveland Clinic study underscores the importance of early detection and treatment of melanoma, the deadliest form of skin cancer. The research, published online today in the Journal of the American Academy of Dermatology, indicates that the sooner patients were treated, the better their survival, particularly for stage I melanoma.



'Busybody' protein may get on your nerves, but that's a good thing

Tue, 17 Oct 17 00:11:00 -0700

Salk researchers find that p75 protein is vital for signaling pain in nervous system.



Study cites race and socioeconomic factors as influential in NSCLC patient survival rates

Mon, 16 Oct 17 00:14:30 -0700

New research found race and specific socioeconomic factors to have a significant influence on disparities in the survival rates of non-small cell lung cancer (NSCLC) patients. Dr. Yanyan Lou of the Mayo Clinic in the United States presented these findings today at the International Association for the Study of Lung Cancer (IASLC) 18th World Conference on Lung Cancer (WCLC) in Yokohama, Japan.



Treatment based On BRCA1 level does not increase survival of stage II/III NSCLC N+ resected patients

Mon, 16 Oct 17 00:01:40 -0700

Research shows that treating stage II and III non-small cell lung cancer (NSCLC) N+ resected patients with customized chemotherapy treatment based on their specific BRCA1 expression levels, as opposed to providing the standard treatment, did not increase overall survival rates among those patients who received individualized CT treatment. Dr. Bartomeu Massuti of Alicante University Hospital in Spain presented his findings today at the International Association for the Study of Lung Cancer (IASLC) 18th World Conference on Lung Cancer (WCLC) in Yokohama, Japan.



Immune response to ovarian cancer may predict survival, Mayo-led study finds

Thu, 12 Oct 17 00:07:20 -0700

A group of international cancer researchers led by investigators from Mayo Clinic and University of New South Wales Sydney has found that the level of a type of white blood cell, called tumor-infiltrating lymphocytes, present in the tumors of patients with high-grade ovarian cancer may predict a patient's survival.



Even modest oil exposure can harm coastal and marine birds

Thu, 12 Oct 17 00:13:30 -0700

Many birds and other wildlife die following an oil spill, but there are also other potential long-terms effects of oil exposure on animals.



Livestock grazing management compatible with nesting greater sage-grouse

Thu, 12 Oct 17 00:01:30 -0700

A new study published in the Journal of Wildlife Management looks at whether management of livestock grazing may help protect sagebrush and birds that depend on it.



Safety, not food, entices geese to cities

Wed, 11 Oct 17 00:13:10 -0700

Canada Geese have shifted their winter range northward in recent years by taking advantage of conditions in urban areas -- but what specific features of cities make this possible? A new study from The Condor: Ornithological Applications suggests that rather than food, geese are seeking safety, congregating in areas where they can avoid hunters and be buffered from the coldest winter temperatures.



International experts describe a new way of cells behaving when submitted to chemotherapy

Tue, 10 Oct 17 00:13:00 -0700

The experts indicate a new way via which cells can respond to chemotherapy. This knowledge has to help constitute the basis for future tools as well as the prognosis of therapeutic interventions, That is to say, on one hand, the functionality of this method can be used to predict the response of the tumor to chemotherapy, which can help with the stratification of patients and the design of personalized treatments.



Insight into our 50-plus lifespan still evolving, genetic study shows

Mon, 09 Oct 17 00:04:10 -0700

The scientific reasons why people live beyond the age of 50 are more complex than thought, according to a new genetic study.



Penn team shows how seemingly acute viral infections can persist

Fri, 06 Oct 17 00:03:10 -0700

Led by Carolina López of the University of Pennsylvania, a multi-disciplinary research team has resolved a paradox of viral infection. They've identified how a viral product can both trigger an immune response aimed at eliminating the virus or, conversely, allow the virus to survive and persist.



Use of CPR, defibrillators improves after public health initiatives

Wed, 04 Oct 17 00:05:10 -0700

After coordinated and comprehensive public health initiatives in North Carolina, more patients received bystander CPR and first-responder defibrillation at home and in public, which was associated with improved survival, according to a study published by JAMA Cardiology.



No clear evidence that most new cancer drugs extend or improve life

Wed, 04 Oct 17 00:15:10 -0700

The majority of cancer drugs approved in Europe between 2009 and 2013 entered the market without clear evidence that they improved survival or quality of life for patients, finds a study published by The BMJ today.



Trastuzumab treatment need not delay breast reconstruction following mastectomy

Tue, 03 Oct 17 00:10:20 -0700

Treatment with trastuzumab (Herceptin/Genentech) of breast cancers that express the HER-2 protein does not increase the risk for complications at the surgical site for women who undergo immediate breast reconstruction after mastectomy. The first study to assess the effect of trastuzumab on surgical wound complications indicates that breast reconstruction need not be delayed because of the type or length of this form of adjuvant therapy.



Researchers look to protect 'self-reactive' immune cells so they can fight melanoma

Thu, 28 Sep 17 00:09:30 -0700

UNC Lineberger Comprehensive Cancer Center researchers and colleagues report on a potential new way to fight melanoma by blocking one of the immune system's checks and balances.



Study examines survival of very low birthweight babies

Wed, 27 Sep 17 00:09:10 -0700

A new study published in Acta Paediatrica indicates that survival of babies born weighing ?500 g is poor despite advances in neonatal care.



Back from the brink

Wed, 27 Sep 17 00:11:40 -0700

UCSB biologists explore the molecular underpinnings of cells that recover from the verge of programmed death.



DNA-level biomarker can predict overall survival for rare brain tumors

Tue, 26 Sep 17 00:12:30 -0700

MGMT promoter methylation status -- information gathered at a DNA-level -- can help predict overall survival for patients with a rare form of brain cancer known as anaplastic astrocytoma, according to a new analysis from The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James).