Subscribe: Brightsurf Science News :: Cell Biology News
Added By: Feedage Forager Feedage Grade A rated
Language: English
biology  brain  cancer  cell  cells  new  published  research  researchers  scientists  stem cells  stem  study  university 
Rate this Feed
Rate this feedRate this feedRate this feedRate this feedRate this feed
Rate this feed 1 starRate this feed 2 starRate this feed 3 starRate this feed 4 starRate this feed 5 star

Comments (0)

Feed Details and Statistics Feed Statistics
Preview: Brightsurf Science News :: Cell Biology News

Cell Biology Current Events and Cell Biology News from Brightsurf

Cell Biology Current Events and Cell Biology News Events, Discoveries and Articles from Brightsurf

Copyright: Copyright 2017,

University of Guelph professor identifies protein key to cancer cells ability to spread

Fri, 17 Nov 17 00:08:50 -0800

U of G scientists have made a discovery that could reduce the spread of cancer by hindering a protein that binds cancer cells together and allows them to invade tissues. The groundbreaking study identified a protein, known as cadherin-22, as a potential factor in cancer metastasis, or spread, and showed that hindering it decreased the adhesion and invasion rate of breast and brain cancer cells by up to 90 percent.

Inner clock: Biologists research the mechanism of an auxiliary clock

Fri, 17 Nov 17 00:11:20 -0800

In December, the Nobel Prize for Medicine and Physiology will be awarded for the identification of genes that control the inner clock. The honoured academics examined fruit flies to determine the biorhythm. Biochemist Professor Dr. Dorothee Staiger of Bielefeld University has been researching the inner clock of plants for twenty years. Her team has now published a new study in the research journal Genome Biology.

Investigating patterns of degeneration in Alzheimer's disease

Fri, 17 Nov 17 00:10:40 -0800

Alzheimer's disease (AD) is known to cause memory loss and cognitive decline, but other functions of the brain can remain intact. The reasons cells in some brain regions degenerate while others are protected is largely unknown. In a paper to be published in Stem Cell Reports, researchers from Brigham and Women's Hospital have found that factors encoded in the DNA of brain cells contribute to the patterns of degeneration, or vulnerability, in AD.

Secrets of succulents' water-wise ways revealed

Thu, 16 Nov 17 00:06:10 -0800

Plant scientists at the University of Liverpool have revealed new insights into the mechanisms that allow certain plants to conserve water and tolerate drought. The research, which is published in The Plant Cell, could be used to help produce new crops that can thrive in previously inhospitable, hot and dry regions across the world.

Yale team's advance allows gene editing with surgical precision

Thu, 16 Nov 17 00:08:50 -0800

Yale researchers report they have created a more precise and efficient technology to edit the genomes of living organisms, an ability that is transforming medicine and biotechnology. The new method, described Nov. 16 in the journal Cell, eliminates some of the drawbacks of genome editing technologies, which enables scientists to insert or eliminate genes within DNA.

To trim away a protein

Thu, 16 Nov 17 00:10:20 -0800

Scientists present a novel method to directly and rapidly destroy any protein in any kind of cell.

NIST scientists discover how to switch liver cancer cell growth from 2-D to 3-D structures

Thu, 16 Nov 17 00:10:10 -0800

A discovery might help designers of miniature 'lab-on-a-chip' technologies to grow three-dimensional colonies of cancer cells inside a chip's tiny chambers, rather than the merely two-dimensional colonies that they generally can culture now. Chips with 3-D cell arrays could furnish more realistic biological environments for drug testing.

Chance discovery of forgotten 1960s 'preprint' experiment

Thu, 16 Nov 17 00:15:40 -0800

Researchers in physics and mathematics have long used 'preprints' -- preliminary versions of their scientific findings published on internet servers for anyone to read. In 2013, similar services were launched for biology, but following a chance discovery, Matthew Cobb, a scientist and historian at the University of Manchester, has unearthed a long-forgotten experiment in biology preprints that took place in the 1960s. He has written about them in a study publishing Nov. 16 in the open-access journal PLOS Biology.

Targeting cancer without destroying healthy T-cells

Wed, 15 Nov 17 00:05:50 -0800

A unique approach to targeting the abnormal T-cells that cause T-cell lymphomas could offer hope to patients with the aggressive and difficult-to-treat family of cancers, finds a study involving researchers from Cardiff University.

Stem cells fail to alleviate peripheral artery disease

Wed, 15 Nov 17 00:08:50 -0800

A stem cell therapy did not improve walking ability in people with peripheral artery disease, although exercise did lead to significant improvements, according to a new study. This is the largest trial of this type of therapy in people with blockages in leg arteries. Scientists were disappointed that stem cell therapy didn't improve walking, because earlier research suggested it could be beneficial.

Protein synthesis machinery from bacterial consortia in one shot

Wed, 15 Nov 17 00:13:00 -0800

A new technique developed at UC Davis may have broken the barrier to rapid assembly of pure protein synthesis machinery outside of living cells.

UT study IDs potential cell receptors to reduce antibiotic resistance

Wed, 15 Nov 17 00:13:50 -0800

The bacterium Pseudomonas aeruginosa is the leading cause of hospital-acquired infections. The pathogen is resistant to many antibiotics so treating those infections, particularly in patients with compromised immune systems, is difficult. A new study from UT has identified certain chemical receptors in cells that could deceive the bacteria and improve patient response to drugs.

Stem cells express genes differently in the lab dish than in the body, study finds

Tue, 14 Nov 17 00:06:10 -0800

Stem cells in the body have a significantly different gene-expression profile than do the same cells when they're isolated in a lab dish, according to researchers at the Stanford University School of Medicine.

Cornell study reveals why testicular cancer is so responsive to chemo

Tue, 14 Nov 17 00:05:40 -0800

Cornell researchers have taken a major step toward answering a key question in cancer research: Why is testicular cancer so responsive to chemotherapy, even after it metastasizes?

Finding a key to unlock blocked differentiation in microRNA-deficient embryonic stem cells

Tue, 14 Nov 17 00:11:40 -0800

In a study published in Stem Cell Reports, Rui Zhao and colleagues have partly solved a long-unanswered basic question about stem cells -- why are pluripotent stem cells that have mutations to block the production of microRNAs unable to differentiate?

Epigenetic editing reveals surprising insights into early breast cancer development

Mon, 13 Nov 17 00:04:00 -0800

Changing the epigenetic code of a single gene is enough to cause a healthy breast cell to begin a chain reaction and become abnormal, according to research by Queen Mary University of London (QMUL).

Engineering non-immune cells to kill cancer cells

Mon, 13 Nov 17 00:14:20 -0800

ETH researchers have reprogrammed normal human cells to create designer immune cells capable of detecting and destroying cancer cells.

Zipping DNA

Mon, 13 Nov 17 00:13:50 -0800

ETH researchers have developed a method that allows large amounts of genetic information to be compressed and then decompressed again in cells. This could aid in the development of new therapies.

Harder for T cells to fight cancer in absence of VEGF-A

Mon, 13 Nov 17 00:02:00 -0800

Contrary to what was previously believed, the immune system's cancer-killing T cells are more effective in a tumour's anoxic environment when they have access to growth factor VEGF-A. In a study from Karolinska Institutet published in Cancer Cell, the researchers show how the T cells not only survive in this oxygen-depleted micro-environment with the help of transcription factor HIF-1a but also become more effective at killing cancer cells inside it.

Study led by MIT Portugal faculty and alumni finds how to increase the survival time of stem cells

Thu, 09 Nov 17 00:12:00 -0800

A team of researchers from the Faculty of Medicine at the University of Coimbra, led by Dr. Lino Ferreira, MIT Portugal Program Faculty and researcher at the Center for Neuroscience and Cell Biology (CNC) in collaboration with Langer Lab at MIT (USA), has developed a new technology, which is promising to understand and treat ischemic diseases.

Crested pigeons use feathers to sound the alarm

Thu, 09 Nov 17 00:01:20 -0800

Many animals will sound an alarm to alert other members of their group of impending danger. Now, researchers reporting in Current Biology on Nov. 9 have shown that crested pigeons do this in a surprisingly non-vocal way. One of their main flight feathers produces a critical high-pitched sound as the birds fly away. As they flap faster to escape a predator, that alarm signal automatically increases in tempo.

How to control traffic on cellular highways

Thu, 09 Nov 17 00:00:50 -0800

Inside cells, protein 'motors' act like trucks on tiny cellular highways to deliver life-sustaining cargoes. Now a team led by Rutgers University-New Brunswick researchers has discovered how cells deploy enzymes to place traffic control and 'roadway under construction' signs along cellular highways.

Frequent alcohol drinking kills new brain cells in adults, females are more vulnerable

Thu, 09 Nov 17 00:00:40 -0800

Researchers from The University of Texas Medical Branch at Galveston recently discovered that alcohol killed the stem cells residing in adult mouse brains. The researchers also found that brain stem cells in key brain regions of adult mice respond differently to alcohol exposure, and they show for the first time that these changes are different for females and males. The findings are available in Stem Cell Reports.

Scientists figure out how cell division timer works

Thu, 09 Nov 17 00:00:20 -0800

Human cells use a timer to divide: each cell gets at least 30 minutes to divide its genetic material between the nuclei of two daughter cells. Researchers at KU Leuven, Belgium, have unravelled how this timer is switched on and off. Their findings open up perspectives for the treatment of cancer, as keeping the timer going would stop cancer cells from dividing.

Reducing the burden of neglected tropical diseases requires investments in basic research

Thu, 09 Nov 17 00:04:30 -0800

International support for measures to prevent neglected tropical diseases has resulted in public health gains, but eliminating these debilitating conditions will require significant investments in basic research, argues Dr. Peter Hotez in a new article publishing Nov. 9 in the open-access journal PLOS Biology.

Size matters: How thrips choose their partners

Wed, 08 Nov 17 00:10:20 -0800

The bigger the male, the higher his chances to successfully mate -- this applies, at least, to thrips, insects that are hard to recognise with the naked eye. The larger males not only drive off their smaller rivals, they also have better immune systems and produce more sperm. This is a discovery that was made by biologists at Martin Luther University Halle-Wittenberg (MLU) that recently appeared in the international Journal of Insect Behaviour.

Early intervention may hold key to treatment of Friedreich's ataxia

Wed, 08 Nov 17 00:11:30 -0800

Current treatments may be administered too late to target Friedreich's ataxia effectively. New research using a slow-onset frataxin knock-in/knockout mouse model showed significantly reduced levels of mitochondrial biosynthesis proteins and early mitochondrial deficiency in the cerebellar cortex, even at pre-symptomatic stages of development. This suggests that the progressive degeneration in mitochondrial function seen in individuals with Friedreich's ataxia is not only the mechanism causing the disease, but also a potential biomarker and therapeutic target.

Protect the skin, build barriers: Old acquaintance in a new role

Wed, 08 Nov 17 00:13:40 -0800

To ensure the barrier function of the skin, mutual regulation of connections between epidermal cells and a receptor for growth factors is necessary. These findings can help to reduce the effects of inflammatory skin diseases and the decreased barrier function of the aged skin. The mechanism was described by a team of researchers led by Carien Niessen of the Cluster of Excellence for aging research, CECAD/Cologne. The results have been published in Nature Communications.

Star-shaped brain cells orchestrate neural connections

Wed, 08 Nov 17 00:01:50 -0800

The unique architecture of star-shaped brain cells called astrocytes plays a key role in regulating the development and function of neural synapses in the brain, says new research by Duke University. The findings indicate that astrocyte dysfunction may underlie neuronal problems observed in devastating diseases like autism, schizophrenia and epilepsy.

Inner ear stem cells may someday restore hearing

Tue, 07 Nov 17 00:03:10 -0800

Want to restore hearing by injecting stem cells into the inner ear? Well, that can be a double-edged sword. Inner ear stem cells can be converted to auditory neurons that could reverse deafness, but the process can also make those cells divide too quickly, posing a cancer risk, according to a study led by Rutgers University-New Brunswick scientists.

Why plants form sprouts in the dark

Tue, 07 Nov 17 00:07:00 -0800

A signal from the cell wall decides that, in the dark, seeds grow into long yellow sprouts, instead of turning green and forming leaves. The signal that switches on the darkness programme in seedling development has not hitherto been identified. Earlier studies had shown that these processes involve photoreceptors inside plant cells. One vital signal outside the cells has now been described by a team from Germany, Australia, France, and Switzerland in the journal Current Biology.

A little stress is good for cellular health and longevity

Tue, 07 Nov 17 00:13:50 -0800

Northwestern University molecular bioscientists have discovered that a little stress can be good for cellular health. The findings will help researchers better understand the molecular mechanisms that drive aging and risk for age-associated degenerative diseases.

Not so different after all: Human cells, hardy microbes share common ancestor

Tue, 07 Nov 17 00:08:40 -0800

Researchers have found striking parallels between how archaeal cells and more complex cells, including humans' and animals', package and store their genetic material. The breakthrough study, published in Science earlier this year, provided evidence that archaea and eukaryotic cells share a common mechanism to compact, organize and structure their genomes.

Researchers discover new pathway for handling stress

Mon, 06 Nov 17 00:01:00 -0800

Researchers at the University of California San Diego studying how animals respond to infections have found a new pathway that may help in tolerating stressors that damage proteins. Naming the pathway the Intracellular Pathogen Response or 'IPR,' the scientists say it is a newly discovered way for animals to cope with certain types of stress and attacks, including heat shock.

Breaking cell symmetry

Mon, 06 Nov 17 00:02:20 -0800

A team of researchers from the Mechanobiology Institute, Singapore at the National University of Singapore, along with colleagues from Temasek Life Sciences Laboratory and A*STAR's Institute of Molecular and Cell Biology in Singapore, has uncovered a novel mechanism for establishing cell polarity that relies on tension force induced clustering of proteins.

Stem cells pave the way for new treatment of diabetes

Mon, 06 Nov 17 00:05:40 -0800

A new stem cell study conducted at the University of Copenhagen shows how we may increase the vital production of insulin in patients suffering from diabetes. The discovery helps to more efficiently at less cost make insulin-producing beta cells from human stem cells. Therefore, the research paves the way for more effective treatment of diabetes. The method may also prove significant to the treatment of a series of other diseases.

Immune cells mistake heart attacks for viral infections

Mon, 06 Nov 17 00:08:00 -0800

A study led by Kevin King, a bioengineer and physician at the University of California San Diego, has found that the immune system plays a surprising role in the aftermath of heart attacks. The research could lead to new therapeutic strategies for heart disease. Researchers present the findings in the Nov. 6 issue of Nature Medicine.

Subset of carbon nanotubes poses cancer risk similar to asbestos in mice

Mon, 06 Nov 17 00:12:50 -0800

Researchers have shown for the first time in mice that long and thin nanomaterials called carbon nanotubes may have the same carcinogenic effect as asbestos: they can induce the formation of mesothelioma. The findings were observed in 10 percent -- 25 percent of the 32 animals included in the study, which has not yet been replicated in humans. The work appears Nov. 6 in Current Biology.

For these baleen whales, hunting requires little more than treading water

Mon, 06 Nov 17 00:12:40 -0800

Rorqual whales are known for their lunge-feeding behavior. As the name suggests, this method involves lunging forward with mouth opened wide to engulf large quantities of water, which is then strained through baleen plates to leave tiny prey behind. But researchers have made the surprising discovery that Bryde's whales also find food in a much more relaxed way: they simply lift their heads at the surface, allowing water and prey to flow in.

Flavonoid derivatives targeting NF-kappaB

Mon, 06 Nov 17 00:13:30 -0800

The aim of the study was to develop new synthetic anti-inflammatory and cytotoxic agents targeting NF-kappaB.

Potential new treatment for Fragile X targets one gene to affect many

Fri, 03 Nov 17 00:05:20 -0700

Scientists found that inhibiting a regulatory protein alters the intricate signaling chemistry that is responsible for many of the disease's symptoms. The findings provide a path to possible therapeutics for disorders associated with Fragile X.

Study refutes using anti-malaria drug to treat diabetes

Fri, 03 Nov 17 00:05:50 -0700

A drug used to treat malaria does not, after all, create new insulin-producing cells, according to a new paper from researchers at UC Davis. The work, published in Cell Metabolism Nov. 3, refutes a study published in Cell in January.

Scratching the surface of mature monocytes...and coming up with CXCR7

Fri, 03 Nov 17 00:05:40 -0700

New research published online in the Journal of Leukocyte Biology showed for the first time that mature monocytes (a specific type of white blood cell) express the CXCR7 receptor on their surface. This receptor may be a therapeutic target for controlling inflammation in the brain associated with diseases like multiple sclerosis, Parkinson's and AIDS

Scientists decipher mechanisms underlying the biology of aging

Thu, 02 Nov 17 00:02:40 -0700

Scientists have helped decipher the dynamics that control how our cells age, and with it implications for extending human longevity. The group employed a combination of technologies to analyze molecular processes that influence aging. Using cutting-edge computational and experimental approaches the scientists discovered that a complete loss of chromatin silencing leads to accelerated cell aging and death. However, the researchers similarly found that continuous chromatin silencing also leads cells to a shortened lifespan.

New insights into the release of molecules involved in inflammatory diseases

Thu, 02 Nov 17 00:04:50 -0700

In a recent study published in Cell Reports, a research team led by Colin Adrain, from the Instituto Gulbenkian de Ciência (IGC, Portugal), discovered the mechanism that controls the release of important molecules that trigger the inflammatory response during the clearance of infections. When this machinery is deregulated it can contribute to important chronic diseases such as inflammatory bowel disease, arthritis, and cancer.

Male mammoths more often fell into 'natural traps' and died, DNA evidence suggests

Thu, 02 Nov 17 00:08:50 -0700

Researchers who have sexed 98 woolly mammoth specimens collected from various parts of Siberia have discovered that the fossilized remains more often came from males of the species than females. They speculate that this skewed sex ratio exists in the fossil record because inexperienced male mammoths more often traveled alone and got themselves killed by falling into natural traps that made their preservation more likely. The findings are reported in Current Biology on Nov. 2.

Newly discovered orangutan species is 'among the most threatened great apes in the world'

Thu, 02 Nov 17 00:08:40 -0700

Scientists have long recognized six living species of great ape aside from humans: Sumatran and Bornean orangutans, eastern and western gorillas, chimpanzees, and bonobos. But researchers reporting in Current Biology on Nov. 2 have now made it seven, based on a collection of evidence showing that an isolated population of orangutans living in Sumatra is actually its own unique species. They've named the new species the Tapanuli orangutan (Pongo tapanuliensis).

How chromosomes 'cheat' for the chance to get into an egg

Thu, 02 Nov 17 00:10:30 -0700

Chromosomes can 'cheat,' biasing the chance that they will make it into a sex cell. A team from the University of Pennsylvania shows how this bias arises in female cells, detecting molecular signals that create an asymmetry in the machinery that drives meiosis, the cell-division process that gives rise to gametes.

Fantastic journey: How newborn neurons to find their proper place in the adult brain

Thu, 02 Nov 17 00:12:40 -0700

This week in the Journal of Cell Biology, Professor Linda Van Aelst and colleagues at Cold Spring Harbor Laboratory (CSHL) describe for the first time (in mice) how baby neurons -- precursors called neuroblasts, generated from a permanent pocket of stem cells in a brain area called the V-SVZ -- make an incredible journey from their place of birth through a special tunnel called the RMS to their target destination in the olfactory bulb.

Scientists trace the stem cells that repopulate bone marrow after transplantation

Wed, 01 Nov 17 00:05:50 -0700

Scientists have finally tracked down the precise subset of blood-forming (also known as hematopoietic) stem cells, or HSCs, that are capable of fully repopulating the bone marrow after transplantation in nonhuman primates.