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Parasites Current Events and Parasites News from Brightsurf

Parasites Current Events and Parasites News Events, Discoveries and Articles from Brightsurf

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AI 'scientist' finds that toothpaste ingredient may help fight drug-resistant malaria

Thu, 18 Jan 18 00:11:30 -0800

An ingredient commonly found in toothpaste could be employed as an anti-malarial drug against strains of malaria parasite that have grown resistant to one of the currently used drugs. This discovery, led by researchers at the University of Cambridge, was aided by Eve, an artificially intelligent 'robot scientist.'

Closed marriage: An orchid that never blooms

Thu, 11 Jan 18 00:03:20 -0800

'When plants give up photosynthesis, this changes their relationship with other organisms, such as the insects who may pollinate them', comments Professor Suetsugu.

How the malarial parasite is evading our arsenal of drugs

Thu, 11 Jan 18 00:15:00 -0800

A team of researchers has identified numerous mutations that allow the malaria-causing parasite Plasmodium falciparum to become resistant to treatment. Knowing the identity of genes that impart multidrug resistance is important for the design of new drugs, and for understanding how existing therapeutics can lose their efficacy in clinical settings.

Researchers map druggable genomic targets in evolving malaria parasite

Thu, 11 Jan 18 00:14:40 -0800

Researchers at University of California San Diego School of Medicine, with colleagues across the country and around the world, have used whole genome analyses and chemogenetics to identify new drug targets and resistance genes in 262 parasite cell lines of Plasmodium falciparum -- protozoan pathogens that cause malaria -- that are resistant to 37 diverse antimalarial compounds.

Experts raise concerns over raw meat diets for cats and dogs

Thu, 11 Jan 18 00:02:30 -0800

In the Vet Record today, a team of researchers based in The Netherlands say these diets may be contaminated with bacteria and parasites, and as such may pose a risk to both animal and human health.

Study: Sleeping sickness not just a sleeping disorder

Thu, 04 Jan 18 00:10:40 -0800

An international study from the Instituto de Medicina Molecular shows one of Africa's most lethal diseases is actually a circadian rhythm disorder caused by the acceleration of biological clocks controlling a range of vital functions besides sleep.

Hijacker parasite blocked from infiltrating blood

Thu, 04 Jan 18 00:05:20 -0800

A major international collaboration led by Melbourne researchers has discovered that the world's most widespread malaria parasite infects humans by hijacking a protein the body cannot live without. The researchers were then able to successfully develop antibodies that disabled the parasite from carrying out this activity.

A phospholipid pathway from plants to parasites

Fri, 29 Dec 17 00:01:30 -0800

Recent findings by researchers at Washington University in St. Louis may aid in the development of therapies to treat parasitic infections, including malaria, and may help plant scientists one day produce hardier crops. The research team's work will be published in the Dec. 29 issue of the Journal of Biological Chemistry.

The shrinking moose of Isle Royale

Mon, 18 Dec 17 00:10:20 -0800

Climate change and predator-prey dynamics with wolves make for smaller moose. Ecologists compare skull measurements spanning four decades gathered at Isle Royale National Park. For the booming moose population of Isle Royale, a key species in the world's longest running predator-prey study on the island, skulls have shrunk by about 16 percent over a 40-year period.

Researchers identify way to weaken malaria parasites against popular drug treatment

Thu, 14 Dec 17 00:03:30 -0800

Indiana University researchers have identified a way to block the ability of parasites that cause malaria to shield themselves against drug treatments in infected mice--a finding that could lead to the development of new approaches to combat this deadly disease in humans.

Finding a lethal parasite's vulnerabilities

Thu, 14 Dec 17 00:08:10 -0800

Researchers from Penn's School of Veterinary Medicine have landed on encouraging findings to take on Strongyloides stercoralis, a parasitic nematode that's infected millions of people around the world.

Does Chagas disease present a health risk to Canadians?

Wed, 13 Dec 17 00:03:30 -0800

Believe it or not, a tropical blood parasite native to Latin America could be harmful to Canadians. Infectious diseases like malaria or Zika may have dominated recent headlines but Chagas -- the 'Kissing Bug' disease -- is in the spotlight following the publication of a new case study in the Canadian Medical Association Journal. Experts from Winnipeg and Montreal warn natives of Latin America and their offspring are at risk of contracting Chagas disease.

Dinosaur parasites trapped in 100-million-year-old amber tell blood-sucking story

Tue, 12 Dec 17 00:09:10 -0800

Fossilized ticks discovered trapped and preserved in amber show that these parasites sucked the blood of feathered dinosaurs almost 100 million years ago, according to a new article published in Nature Communications today.

Turning pathogens against each other to prevent drug resistance

Mon, 11 Dec 17 00:11:30 -0800

Limiting a much-needed resource could pit pathogens against one another and prevent the emergence of drug resistance. New research demonstrates that harnessing competition among pathogens inside a patient could extend the life of existing drugs where resistance is already present and prevent resistance to new drugs from emerging. A paper describing this ecological approach to drug resistance appears the week of Dec. 11 in the journal Proceedings of the National Academy of Sciences.

How malaria tricks the immune system

Thu, 07 Dec 17 00:12:00 -0800

The new study suggest a possible defense in the battle against this deadly disease.

How the cat parasite exploits immune cells to reach the brain

Thu, 07 Dec 17 00:03:50 -0800

Scientists have previously shown that a parasite from cats can infect people's brain and affect our behaviour. Now, researchers at Stockholm University have discovered how the parasite takes control of our cells.

Dibenzoazepine defender: Drug found to be effective against resistant hepatitis C

Wed, 06 Dec 17 00:06:50 -0800

Osaka University researchers identify class of chemicals that can combat resistant strains of the hepatitis C virus, as well as parasites that cause malaria and toxoplasmosis

Discovery of key molecules involved in severe malaria

Mon, 04 Dec 17 00:14:40 -0800

A research group led by Osaka University found that proteins called RIFIN expressed on erythrocytes infected with Plasmodium falciparum help the parasite to suppress the host immune response, causing severe malaria. These findings are expected to contribute to the development of effective vaccines and therapeutic drugs against malaria.

A new research agenda to accelerate malaria elimination and eradication

Thu, 30 Nov 17 00:07:20 -0800

Over 180 scientists, malaria programme managers and policy makers from around the world have come together through a consultative process to update the research agenda for malaria elimination and eradication, first produced in 2011. The outcome is a series of seven 'malERA Refresh' papers published in PLOS Medicine. This forward-looking research and development agenda should help accelerate progress towards a malaria-free world.

Malaria: Protective antibodies following natural infection

Tue, 28 Nov 17 00:01:20 -0800

No effective vaccine exists to date against the tropical disease malaria. Scientists from the German Cancer Research Center have now studied how the human immune system responds to natural infection by the malaria parasite. Analyzing individual immune cells, they discovered that the immune system produces antibodies that are protective against the disease in mice. In addition, long-lived memory cells are formed and produce this antibody again if needed. These findings will help develop more specific next-generation vaccines.

Strong hosts help parasites spread farther

Wed, 22 Nov 17 00:09:20 -0800

Large, physically strong Masu salmon disperse farther when infected with parasites, potentially escaping from further infections at the contaminated site but ironically resulting in the greater expansion of the parasite, according to Hokkaido University researchers.

The genome of Leishmania reveals how this parasite adapts to environmental changes

Wed, 22 Nov 17 00:01:50 -0800

Scientists demonstrate that Leishmania adaptation results from frequent and reversible chromosomal amplifications. This novel insight into Leishmania genomic instability should pave the way for the identification of parasite drug resistance mechanisms and help discover biomarkers.

Penn study identifies new malaria parasites in wild bonobos

Tue, 21 Nov 17 00:04:40 -0800

Malaria parasites, although widespread among wild chimpanzees and gorillas, have not been detected in bonobos, a chimp cousin. Although the researchers saw evidence of a new malaria species in bonobos, it was limited to one small area of their range. This work helps the hunt for biological loopholes to potentially exploit the life history of ape pathogens to better understand how they cross over to humans.

Newly found immune defence could pave way to treat allergies

Thu, 16 Nov 17 00:05:20 -0800

Scientists have made a fundamental discovery about how our body's immune system clears harmful infections.

Tapeworm drug fights prostate cancer

Wed, 15 Nov 17 00:00:30 -0800

A medicine against parasites contains a substance that kills prostate and colon cancer.

UTEP team advances in developing vaccine for cutaneous leishmaniasis

Wed, 15 Nov 17 00:05:40 -0800

A research team at The University of Texas at El Paso is one step closer to developing an effective human vaccine for cutaneous leishmaniasis. During the team's more than four years of research at UTEP's Border Biomedical Research Center, they discovered a vaccine formulation that resulted in a 96 percent decrease in the lesions caused by the illness and showed an 86 percent protection rate from the disease in mice.

Protein synthesis machinery from bacterial consortia in one shot

Wed, 15 Nov 17 00:13:00 -0800

A new technique developed at UC Davis may have broken the barrier to rapid assembly of pure protein synthesis machinery outside of living cells.

Parasites suck it up

Thu, 09 Nov 17 00:00:30 -0800

Depletion of a fatty molecule in human blood propels malaria parasites to stop replicating and causing illness in people and instead to jump ship to mosquitoes to continue the transmission cycle, according to a new study by an international research team.

Reducing the burden of neglected tropical diseases requires investments in basic research

Thu, 09 Nov 17 00:04:30 -0800

International support for measures to prevent neglected tropical diseases has resulted in public health gains, but eliminating these debilitating conditions will require significant investments in basic research, argues Dr. Peter Hotez in a new article publishing Nov. 9 in the open-access journal PLOS Biology.

Cell phone-based microscope leads to possible strategy for treating river blindness

Wed, 08 Nov 17 00:09:30 -0800

River blindness, or onchocerciasis, is a disease caused by a parasitic worm (Onchocerca volvulus) found primarily in Africa. Ivermectin is used to treat onchocerciasis. This treatment can be fatal when a person has high blood levels of another worm, Loa loa. In a paper published in NEJM, scientists describe how a cell phone-based videomicroscope can provide fast, effective testing for L. loa parasites, allowing these individuals to be protected from the adverse effects of ivermectin.

Fish provide insight into the evolution of the immune system

Mon, 06 Nov 17 00:04:50 -0800

New research reveals how immune systems can evolve resistance to parasites. The study published in Nature Communications, solves the enigma of how species can adapt and change their immune system to cope with new parasitic threats -- whilst at the same time showing little or no evolutionary change in critical immune function over millions of years. It help to explain why we humans have some immune genes that are almost identical to those of chimpanzees.

Could this be malaria's Achilles heel?

Mon, 06 Nov 17 00:07:50 -0800

Portuguese researchers at Instituto de Medicina Molecular (iMM) Lisboa have identified a defence mechanism by which the malaria parasite can survive inside its host's liver cells.

Biological clock found in fungal parasite sheds more light on 'zombie ants' phenomenon

Mon, 06 Nov 17 00:15:30 -0800

A working biological clock has been found in a fungal parasite that infects ants to control their behavior and lead them away from their nests in an effort to spread their fungal spores more effectively.

Digger wasps and their chemistry

Fri, 03 Nov 17 00:01:10 -0700

Astonishing evolution: Because digger wasps switched prey, the chemical protective layer of their skin changed, too.

SUTD researchers solve mystery behind red blood cell maturation

Thu, 02 Nov 17 00:16:20 -0700

A team of SUTD researchers profiled the human red blood cell proteome and discovered which proteins were changed during the maturation accounting for the transition in shape and deformability of reticulocytes.

Malaria parasite in the Americas is more genetically diverse than previously thought

Fri, 27 Oct 17 00:03:50 -0700

Researchers discover that populations of Plasmodium vivax on the continent are as genetically diverse as in Southeast Asia, where malaria transmission is more frequent. Vivax's greater genetic diversity in the Americas in comparison with Falciparum species might be explained by a wider range of migratory routes.

Discovery of a potential therapeutic target to combat trypanosomes

Thu, 26 Oct 17 00:05:20 -0700

Using cryo-electron microscopy, French researchers at the Institut de Biologie Moléculaire et Cellulaire (CNRS/Université de Strasbourg) have analyzed the structure of trypanosomes parasites in details and revealed one of their potential weak points, which has remained undetected until now. This discovery opens the path to the development of new safer therapies that are less toxic and more specific against trypanosomes, the parasites causing the Chagas disease and the African sleeping sickness.

NIH study identifies new targets for anti-malaria drugs

Thu, 26 Oct 17 00:10:20 -0700

The deadliest malaria parasite needs two proteins to infect red blood cells and exit the cells after it multiplies, a finding that may provide researchers with potential new targets for drug development, according to researchers funded by the National Institutes of Health. Their study appears in the latest issue of Science.

A new weapon against malaria

Thu, 26 Oct 17 00:10:00 -0700

Malaria is a parasitic disease transmitted between humans through the bite of a mosquito. By identifying two proteases essential for the parasite's survival and dissemination as well as a molecule capable of inhibiting them, researchers at UNIGE and UNIBE bring a new hope in the fight against malaria. Their discovery could lead to the development of drugs blocking not only the parasite development in human beings, but also the human to mosquito transmission and vice-versa.

New combination therapy of registered drugs shortens anti-Wolbachia therapy

Tue, 24 Oct 17 00:11:50 -0700

Researchers from LSTM's Research Centre for Drugs and Diagnostics have found a way of significantly reducing the treatment required for lymphatic filariasis and onchocerciasis from several weeks to seven days. By targeting Wolbachia, a bacterial symbiont that the filarial parasites need to live, the team has discovered a drug synergy that enables effective treatment over a shorter time.

Immune reaction to sandfly saliva varies between individuals living in endemic areas

Thu, 12 Oct 17 00:16:30 -0700

The Phlebotomus papatasi sandfly is responsible for spreading Leishmania throughout the tropics and subtropics. How individuals in areas endemic for Leishmania infection react to sandfly saliva depends on their long-term exposure to the flies, researchers now report PLOS Neglected Tropical Diseases TK.

Parasite study paves way for therapies to tackle deadly infections

Tue, 10 Oct 17 00:13:40 -0700

New understanding of a parasite that causes a million cases of disease each year could point towards effective drug treatments.

Genetic advance for male birth control

Tue, 10 Oct 17 00:14:40 -0700

When it comes to birth control, many males turn to two options: condoms or vasectomies. While the two choices are effective, both methods merely focus on blocking the transportation of sperm.

Study warns of pumpkin-colored zombies

Mon, 09 Oct 17 00:07:30 -0700

Salt marsh research shows that growing abundance of tiny shrimp infected by a microscopic parasite may portend future threats to humankind through disease.

Research identifies potential targets for treatment of leishmaniasis

Thu, 05 Oct 17 00:01:20 -0700

Brazilian scientists show that parasite's penetration of host cells increases expression of certain microRNAs capable of inhibiting action of immune system.

Researchers demonstrate engineering approach to combine drugs, control parasitic worms

Wed, 04 Oct 17 00:10:30 -0700

An international research team that includes engineers from Iowa State University has demonstrated that an engineering technology that's been used in cell studies can also be used for drug testing on parasitic roundworms used as a model whole organism. In this case, the technology quickly developed a cocktail of four drugs that was effective in paralyzing the roundworms. The discovery is reported in the journal Science Advances.

Tiny poisonous Brazilian frogs are 'deaf' to their own call

Tue, 03 Oct 17 00:05:40 -0700

Tiny Brazilian frogs still 'sing' despite not being able to hear themselves -- this is the surprising discovery of new scientific research.

Central America 'kissing bug' carries two main subtypes of Chagas disease parasite

Thu, 28 Sep 17 00:13:20 -0700

Trypanosoma cruzi, the parasite that causes Chagas disease, is divided into six strains, each of which differs in where they are found and in how important they are in human infections. Now, researchers have found that most T. cruzi parasites in Central America belong to just two of those strains. The results are detailed this week in PLOS Neglected Tropical Diseases.

Promising results for 2 genetic weapons against malaria

Thu, 28 Sep 17 00:13:10 -0700

Antimalarial bacteria and immune-boosted mosquitoes show strong potential to spread in the wild.

Disease resistance successfully spread from modified to wild mosquitoes

Thu, 28 Sep 17 00:10:10 -0700

Using genetically modified mosquitoes to reduce or prevent the spread of disease is a rapidly expanding field of investigation. One challenge is ensuring that GM mosquitoes can mate with their wild counterparts so the desired modification is spread in the wild population. Investigators at Johns Hopkins University have engineered mosquitoes with an altered microbiota that suppresses human malaria-causing parasites. These GM mosquitos preferred to mate with wild mosquitoes and passed the desired protection to offspring.