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Naked molecules dancing in liquid become visible

Mon, 25 Sep 2017 11:18:47 +0200

Moving, vibrating and leaping molecules make up our world. However, capturing their movement is not an easy task. IBS scientists at the Center for Soft and Living Matter, within the Institute for Basic Science (IBS), were able to see the movement of molecules stored inside a graphene pocket without ...

Cnidarians remotely control bacteria

Mon, 25 Sep 2017 07:00:15 +0200

In modern life sciences, a paradigm shift is becoming increasingly evident: life forms are no longer considered to be self-contained units, but instead highly-complex and functionally-interdependent communities of organisms. The exploration of the close links between multi-cellular and especially ba...

Steering the Immune Defense against Fungal Pathogens

Mon, 25 Sep 2017 07:00:14 +0200

Fungal infections represent an increasing health crisis, especially for immune-deficient patients. Scientists report that specific help could be provided by small-molecule immunotherapeutics with novel mechanism of action. They developed small bifunctional molecules that simultaneously bind both chi...

Virtual reality tool developed to untangle genes

Mon, 25 Sep 2017 07:00:09 +0200

Researchers from Oxford have been using virtual reality software to compile genetic data to create models which explain how genes are controlled within their natural chromosomal environments. The team from the MRC Weatherall Institute of Molecular Medicine (WIMM) have been working in collaboration w...

First immunotherapy for rare and aggressive skin cancer in the European Union approved

Fri, 22 Sep 2017 07:00:25 +0200

Merck and Pfizer Inc. announced that the European Commission (EC) has granted marketing authorization for BAVENCIO® (avelumab) as a monotherapy for the treatment of adult patients with metastatic Merkel cell carcinoma (mMCC), a rare and aggressive skin cancer. BAVENCIO will have marketing authorizat...

Atriva receives an additional seed financing to develop its influenza therapeutic to clinical stage

Fri, 22 Sep 2017 07:00:20 +0200

The next generation of Antiviral Therapies: Co-Led by Stichting Participatie Atriva and High-Tech Gründerfonds (HTGF), Atriva Therapeutics GmbH has received a second tranche of its running seed financing in total of € 3 Mn from Dutch, German and Canadian investors, after lead compound ATR-002 (Atriv...

Unique property of critical methane-producing enzyme discovered

Fri, 22 Sep 2017 07:00:16 +0200

An unexpected discovery has given scientists a greater understanding of an important methane-producing enzyme. A team of researchers at the Carl R. Woese Institute for Genomic Biology (IGB) at the University of Illinois at Urbana-Champaign outlined their findings on an enzyme called methyl-coenzyme ...

New biomaterial could replace plastic laminates, greatly reduce pollution

Fri, 22 Sep 2017 07:00:05 +0200

An inexpensive biomaterial that can be used to sustainably replace plastic barrier coatings in packaging and many other applications has been developed by Penn State researchers, who predict its adoption would greatly reduce pollution. Completely compostable, the material -- a polysaccharide polyele...

Immune cells may heal bleeding brain after strokes

Fri, 22 Sep 2017 07:00:00 +0200

While immune cells called neutrophils are known to act as infantry in the body's war on germs, a National Institutes of Health-funded study suggests they can act as medics as well. By studying rodents, researchers showed that instead of attacking germs, some neutrophils may help heal the brain after...

Only lethal if sugar is present

Thu, 21 Sep 2017 11:29:15 +0200

The plant toxin ricin is one of the most poisonous naturally occurring proteins, making it an extremely dangerous bioweapon. Ricin attacks have made the headlines a number of times over the years, including the spectacular “umbrella murder” in London in the 1970s, or more recently the ricin letters ...

Molecular Force Sensors

Thu, 21 Sep 2017 07:00:37 +0200

Proteins are often considered as molecular machines. To understand how they work, it is not enough to visualize the involved proteins under the microscope. Wherever machines are at work mechanical forces occur, which in turn influence biological processes. These extremely small intracellular forces ...

Evonik is investing in NUMAFERM

Thu, 21 Sep 2017 07:00:35 +0200

Through its Venture Capital unit, Evonik has invested in the start-up NUMAFERM and now holds a minority share in the spin-off of Heinrich Heine University Düsseldorf. The investment was made as part of a seed financing round and also includes investments by High-Tech Gründerfonds, the Business Angel...

Recipharm signs manufacturing agreement and acquires facility in Spain

Thu, 21 Sep 2017 07:00:16 +0200

Recipharm AB announces that it has entered into collaboration with Roche and signed a long-term manufacturing agreement whereby Recipharm will manufacture a range of solid dose products. Recipharm will also acquire a manufacturing facility currently employing approximately 200 people located in Lega...

Enterome to move its research laboratories

Thu, 21 Sep 2017 07:00:16 +0200

Enterome, a pioneer of innovative therapies for microbiome-related diseases announced that the Company is moving its research laboratories to Genopole, a leading biocluster dedicated to biotechnology and research in genomics and genetics. The new laboratories brings Enterome closer to its existing a...

Fluorescence microscopy on a chip -- no lenses required

Thu, 21 Sep 2017 07:00:09 +0200

Fluorescence microscopy gives researchers incredible power to illuminate the tiniest structures and capture the real-time activities of live cells by tagging biological molecules with a veritable rainbow of fluorescent dyes. This power comes at a cost: The technology can be expensive and time-consum...

Molecular Devices and Cytena Partner collaborate in single cell printing

Wed, 20 Sep 2017 13:13:07 +0200

Molecular Devices, LLC announced a partnership with Cytena GmbH to launch the CloneSelect™ Single-Cell Printer™ in North America. This system utilizes microfluidics-based technology and real-time image analysis to isolate single cells and provide visual documentation of monoclonality for use in cell...

Nanocapsules Enable Cell-Inspired Metabolic Reactions

Wed, 20 Sep 2017 11:27:32 +0200

Researchers at the University of Basel succeeded in developing capsules capable of producing the bio-molecule glucose-6-phosphate that plays an important role in metabolic processes. The researchers were able to produce the metabolite in conditions very similar to the biochemical reaction inside nat...

High-Tech Gründerfonds starts lining up investments for HTGF III fund

Wed, 20 Sep 2017 07:00:07 +0200

High-Tech Gründerfonds’ third fund is now operational After announcing the successful first close at the 2017 Family Day – the biggest event of the year for the venture capital sector in Germany – HTGF has now begun approving investments from the new fund. The launch coincides with HTGF’s publicatio...

Eurofins to acquire EAG Laboratories

Wed, 20 Sep 2017 07:00:04 +0200

Eurofins Scientific announces that it has signed an agreement to acquire EAG Laboratories, a scientific services company providing analytical testing and consulting solutions to a diverse and demanding set of end markets, from Odyssey Investment Partners. The transaction is expected to close in the ...

Kit will identify genetic variations without need for lab analysis

Tue, 19 Sep 2017 11:17:51 +0200

Scheme Lab, a biotech startup incubated at the Center for Innovation, Entrepreneurship & Technology (CIETEC), in São Paulo, Brazil, is developing genetic tests that can be used anywhere - in factories, on farms, or even at home - without the need for analysis by specialized laboratories. These "poin...

US publication provides wrong calculation of development costs of cancer drugs

Tue, 19 Sep 2017 07:00:09 +0200

In a recent study, the US physicians Vinay Prasad and Sham Mailankody from clinics in Portland and New York have calculated the average research and development costs for cancer drugs too low. This is demonstrated by methodological deficiencies in their work: the authors base their research on a sam...

3D-printing materials for wound care and decorative elements

Tue, 19 Sep 2017 07:00:04 +0200

Cellulose nanofibrils have properties that can improve the characteristics of bio-based 3D-printing pastes. VTT Technical Research Centre of Finland is developing a 3D wound care product for monitoring wound condition in hospital care. However, the first commercial nanocellulose applications will be...

Hints from hemoglobin lead to better carbon monoxide storage

Mon, 18 Sep 2017 14:00:09 +0200

Carbon monoxide is an insidious poison because it loves the iron in our blood; it pushes oxygen out of iron-based hemoglobin, leading to painful asphyxiation. This affinity for iron comes in handy in a newly created material that can absorb carbon monoxide far better than other materials, with poten...

Membrane vesicles released by bacteria may play different roles during infection

Mon, 18 Sep 2017 14:00:07 +0200

Bacteria release membrane-derived vesicles (MVs), which are small particles that can transport virulence factors to neighbouring bacteria or to the cells of a mammalian host. This special MV-based system for delivering toxic proteins and nucleic acids in a protected manner to the target cells may ha...

A fat-regulating enzyme could hold the key to diseases

Mon, 18 Sep 2017 14:00:05 +0200

It had already been known that the enzyme known as phosphatidic acid phosphatase plays a crucial role in regulating the amount of fat in the human body. Controlling it is therefore of interest in the fight against obesity. But scientists at Rutgers University-New Brunswick have now found that gettin...

Inhibiting obesity

Mon, 18 Sep 2017 14:00:05 +0200

NAPEs, a family of lipid molecules, are produced in the intestinal tract after food intake and exert leptin-like effects: they reduce food intake and weight gain. Given their potential importance in regulating satiety and inhibiting obesity, Sean Davies , Ph.D., and colleagues are exploring NAPE act...

How Blood Vessels Are Formed

Mon, 18 Sep 2017 14:00:02 +0200

New insights into the development of the vascular system: researchers in the team of Dr Carmen Ruiz de Almodóvar of the Heidelberg University Biochemistry Center have discovered a crucial biological step that regulates the formation of blood vessels. They were able to show that the proteins YAP and ...

Edstrom Industriesa acquires Triple Red

Mon, 18 Sep 2017 14:00:02 +0200

Edstrom Industries LLC announced it has completed the acquisition of Triple Red Ltd. The acquisition furthers Edstrom Industries' efforts to offer a broader range of products and solutions to the research community. Based in the United Kingdom, Triple Red manufactures and sells a broad range of equi...

New dyes detect disease through heartbeat signals

Mon, 18 Sep 2017 11:06:20 +0200

Vibrant tones of yellow, orange, and red move in waves across the screen. Although the display looks like psychedelic art, it's actually providing highly technical medical information -- the electrical activity of a beating heart stained with voltage-sensitive dyes to test for injury or disease. The...

Liquid cats, disgust for cheese and reversed genitalia

Mon, 18 Sep 2017 07:00:13 +0200

This year's ceremony of the Ig Nobel Prize awards again shows how precious some areas of research can be. We had insights into research, which is not common, applicable or believable. Despite earlier awards all winners received the prize personally or send video messages to claim their interest. Her...

Is the Alzheimer's gene the ring leader or the sidekick?

Mon, 18 Sep 2017 07:00:07 +0200

The notorious genetic marker of Alzheimer's disease and other forms of dementia, ApoE4, may not be a lone wolf. Researchers from USC and the University of Manchester have found that another gene, TOMM40, complicates the picture. Although ApoE4 plays a greater role in some types of aging-related memo...

How does a cell maintain its identity during replication?

Mon, 18 Sep 2017 07:00:03 +0200

Prior to cell division, chromosomes are seemingly a jumbled mess. During cell division, parent cell chromosomes and their duplicates sort themselves out by condensing, becoming thousands of times more compact than at any other time. Researchers have long assumed that genes become "silent" during cel...

New genetic cause discovered for photosensitive blood disorder

Mon, 18 Sep 2017 07:00:00 +0200

Researchers from BWH have uncovered a new genetic cause for erythropoietic protoporphyria (EPP), a photosensitive blood disorder. In the past, the most well-known causes for EPP were two specific genetic disorders, but using an extended pedigree from France, the investigators found that EPP can also...

Fast, convenient & standardized: New lab innovation for automated tissue engineering & drug testing

Fri, 15 Sep 2017 11:13:56 +0200

MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing. This lab innovation...

Sartorius Campus expands: Official opening of the new manufacturing facility for laboratory instruments

Fri, 15 Sep 2017 07:00:19 +0200

With its new facility for the manufacture of laboratory instruments, Sartorius provides high-quality production conditions and an advanced, efficient work environment. The biopharmaceutical and laboratory equipment supplier officially opened its approximately 42-million-euro new building as part of ...

Asthma drug from the garden center

Fri, 15 Sep 2017 07:00:14 +0200

The coralberry could offer new hope for asthmatics: researchers at the University of Bonn have extracted a new kind of active pharmaceutical ingredient from its leaves to combat this widespread respiratory disease. In mice, it almost completely inhibits the characteristic contraction of the airways....

Low-level radiation less harmful to health than other lifestyle risks

Fri, 15 Sep 2017 07:00:12 +0200

Low-level radiation exposure poses less of a health risk than other modern lifestyle threats, such as smoking, obesity and air pollution, according to Oxford University research. Human populations have always been exposed to ionizing radiation, and more so in modern life due to its use in medicine, ...

Multifunctional nano-sized drug carriers based on reactive polypept(o)ides

Fri, 15 Sep 2017 07:00:08 +0200

In cooperation with researchers from the University of Tokyo and Gutenberg Research Awardee Prof. Kazunori Kataoka, Chemists from Mainz have been able to demonstrate that reactive polypept(o)ides constitute ideal building blocks to control morphology and function of carrier systems in a simple but p...

A spectroscopic 'science camera' system for smartphones

Fri, 15 Sep 2017 07:00:01 +0200

The latest versions of most smartphones contain at least two and sometimes three built-in cameras. Researchers at the University of Illinois would like to sell mobile device manufactures on the idea of adding yet another image sensor as a built-in capability for health diagnostic, environmental moni...

Transplanted hearts reveals risk gene for cardiovascular disease

Thu, 14 Sep 2017 14:00:03 +0200

In the largest transcriptome study to date, an international research team analysed the RNA of transplanted hearts and discovered a number of new risk factors for dilated cardiomyopathy and other heart conditions which could thus be recognised more easily in future. We know of many genes with varia...

Bristol-Myers Squibb Names Karen Vousden to Board of Directors

Thu, 14 Sep 2017 14:00:03 +0200

Bristol-Myers Squibb Company announced that its Board of Directors has elected Karen Vousden, Ph.D., to the Board, effective January 1, 2018. Dr. Vousden will serve as a member of the Science and Technology Committee of the Board of Directors. Dr. Vousden, 60, is currently group leader at the Franci...

To operate, insert dimers

Thu, 14 Sep 2017 14:00:00 +0200

The presence of DNA in mammalian cell cytoplasm triggers an immune response by binding to a dimeric enzyme, which inserts between DNA double helices to form the “rungs” of a ladder-like structure, as an LMU team has now shown. In higher organisms, the genetic material is normally confined to the cel...

Flexible rechargeable batteries for pacemakers

Thu, 14 Sep 2017 11:13:30 +0200

Experts at Queen’s University Belfast have designed a flexible and organic alternative to the rigid batteries that power up medical implants. Currently, devices such as pacemakers and defibrillators are fitted with rigid and metal based batteries, which can cause patient discomfort. Dr Geetha Sriniv...

EMBO at Basel Life

Thu, 14 Sep 2017 07:00:23 +0200

EMBO and Basel Life hosted EMBO at Basel Life conference. A committee of leading scientists had organized this international and broad-scope scientific conference on current and emerging life science research to be held as part of Basel Life. “Established and young researchers will present and discu...

Affimed Appoints Dr. Wolfgang Fischer as Chief Operating Officer

Thu, 14 Sep 2017 07:00:03 +0200

Affimed N.V. announced  the appointment of Dr. Wolfgang Fischer as Chief Operating Officer. "We are very pleased that Dr. Wolfgang Fischer has joined our management team as COO," said Dr. Adi Hoess, Chief Executive Officer of Affimed. "With his solid track record in drug development and project mana...

Toxic chemicals in building materials even in "green housing"

Wed, 13 Sep 2017 11:22:55 +0200

Indoor air pollution can be a problem in many homes, even in eco-friendly buildings. Thanks to a new innovative study led by Silent Spring Institute, researchers have a better idea of where these pollutants come from--which ones come from chemicals leaching out of building materials and which ones f...

Flying with fuel from sugarcane

Wed, 13 Sep 2017 07:00:06 +0200

A Boeing 747 burns one gallon of jet fuel each second. A recent analysis from researchers at the University of Illinois estimate that this aircraft could fly for 10 hours on bio-jet fuel produced on 54 acres of specially engineered sugarcane. Plants Engineered to Replace Oil in Sugarcane and Sweet S...

Next generation of neuroscience tools

Wed, 13 Sep 2017 07:00:04 +0200

UAlberta chemistry professor Robert Campbell is developing new ways to see and manipulate the activity of neurons in the brain, which could revolutionize the way we understand the organ that controls most of the activities of the body. "We want to help other researchers apply these new neuroscience ...

Revolutionary process could signal new era for gene synthesis

Wed, 13 Sep 2017 07:00:02 +0200

A team of scientists led by the University of Southampton has demonstrated a groundbreaking new method of gene synthesis - a vital research tool with real-world applications in everything from growing transplantable organs to developing treatments for cancer. Current methods for synthesizing genes m...

Eva van Pelt will become new member of the Management Board of Eppendorf AG

Wed, 13 Sep 2017 07:00:01 +0200

On October 1, 2017, Eva van Pelt will assume Management Board responsibility for the area of Commercial Organization and thus worldwide responsibility for sales, marketing and service in the Eppendorf Group. This Management Board mandate was newly created at the end of 2016, and has been under the i...