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Preview: Medscape Diabetes & Endocrinology Headlines

Medscape Diabetes & Endocrinology Headlines



Latest medical news, articles, and features from Medscape Diabetes & Endocrinology



 



Artificial Sweeteners Alter Gut Response to Glucose Artificial Sweeteners Alter Gut Response to Glucose

Wed, 20 Sep 2017 11:12:23 EDT

Large amounts of artificial sweeteners interfere with the gut's response to glucose, increasing both glucose absorption and glycemic response and inhibiting production of GLP-1.
Medscape Medical News



Long-term PTH Linked to Bone Improvements in Hypoparathyroidism Long-term PTH Linked to Bone Improvements in Hypoparathyroidism

Wed, 20 Sep 2017 09:22:08 EDT

Skeletal improvements are seen after 8 to 10 years of treatment; other research shows quality-of-life improvements.
Medscape Medical News



Aortic Aneurysm Risk Is Smaller in Type 2 Diabetes Patients Aortic Aneurysm Risk Is Smaller in Type 2 Diabetes Patients

Wed, 20 Sep 2017 07:52:24 EDT

"While it's good that people with diabetes may get less" aortic aneurysm, they still need to lower blood pressure, control lipids, and stop smoking to prevent overall cardiovascular risk, an expert noted.
Medscape Medical News



Fracture Risk, Bone Loss Increased in HIV-Infected Individuals Fracture Risk, Bone Loss Increased in HIV-Infected Individuals

Tue, 19 Sep 2017 13:09:39 EDT

Studies show an increased risk of vertebral fractures and increased bone loss in individuals with HIV infection, and document effects of vitamin D supplementation among this patient population.
Medscape Medical News



Evolocumab Doesn't Worsen Glycemia or Up Diabetes Risk: FOURIEREvolocumab Doesn't Worsen Glycemia or Up Diabetes Risk: FOURIER

Tue, 19 Sep 2017 12:04:41 EDT

In a large trial with more than 27,000 patients with preexisting CVD and uncontrolled LDL cholesterol, there was no signal of worsening or new-onset diabetes with the PCSK9 inhibitor evolocumab.
Medscape Medical News



Simple Discussion of Emotions Reduces Diabetes Distress in MalaysiaSimple Discussion of Emotions Reduces Diabetes Distress in Malaysia

Tue, 19 Sep 2017 09:09:38 EDT

Healthcare-provider-led discussion around emotions, social care, and healthcare services is as effective as a more complex educational program at reducing diabetes distress in Asia, new research indicates.
Medscape Medical News



Gastric-Bypass Bone Loss Continues 5 Years OutGastric-Bypass Bone Loss Continues 5 Years Out

Mon, 18 Sep 2017 16:09:41 EDT

Even 3 years after weight loss stabilizes, bone loss is shown to continue in various measures in one of the first studies to examine this issue long-term after bariatric surgery.
Medscape Medical News



CGM in Type 1 Diabetes in Pregnancy Cuts Adverse Neonate OutcomesCGM in Type 1 Diabetes in Pregnancy Cuts Adverse Neonate Outcomes

Mon, 18 Sep 2017 12:06:39 EDT

Pregnant women with type 1 diabetes using continuous glucose monitoring had modestly lower HbA1c and a 50% reduced risk of giving birth to a large-for-gestational-age baby in the CONCEPTT study.
Medscape Medical News



Minidose Glucagon for Exercise-Induced Hypoglycemia in T1DMinidose Glucagon for Exercise-Induced Hypoglycemia in T1D

Mon, 18 Sep 2017 08:43:31 EDT

Minidose glucagon given just before moderate intensity exercise prevents hypoglycemia--more so than insulin reduction--in patients with type 1 diabetes.
Medscape Medical News



Targeting Hypoglycemia and Glycemic Variability in T2D? More From DEVOTETargeting Hypoglycemia and Glycemic Variability in T2D? More From DEVOTE

Fri, 15 Sep 2017 10:08:33 EDT

Secondary analyses from the DEVOTE trial comparing the ultralong-acting insulin degludec with insulin glargine examine associations between glycemic variability and severe hypoglycemia and outcomes.
Medscape Medical News



EXSCEL: 'Disappointment' Spurs Discussion on GLP-1 Agonists in DiabetesEXSCEL: 'Disappointment' Spurs Discussion on GLP-1 Agonists in Diabetes

Thu, 14 Sep 2017 16:24:09 EDT

Full details of EXSCEL with the GLP-1 agonist exenatide, in which the agent didn't show any cardiovascular benefit over placebo in type 2 diabetes, provide "some good news" but also "some disappointment."
Medscape Medical News



Acarbose Offers No CVD Protection in ACE, but May Cut Diabetes RiskAcarbose Offers No CVD Protection in ACE, but May Cut Diabetes Risk

Thu, 14 Sep 2017 11:33:32 EDT

A study of acarbose was conducted in a Chinese population with impaired glucose tolerance and established cardiovascular disease.
Medscape Medical News



DEPICT-1: Dapagliflozin Works in T1D With Little Ketoacidosis DEPICT-1: Dapagliflozin Works in T1D With Little Ketoacidosis

Thu, 14 Sep 2017 09:59:38 EDT

Dapagliflozin provided significant reductions in HbA1c, total daily insulin dose, and body weight in type 1 diabetes and was well tolerated, with no new safety signals, in a 24-week trial.
Medscape Medical News



Experts Still Confounded by How to Prevent, Manage HypoglycemiaExperts Still Confounded by How to Prevent, Manage Hypoglycemia

Thu, 14 Sep 2017 08:17:40 EDT

Clinicians, advocates, and federal officials said the pressing public-health problem of hypoglycemia should be considered an outcome, not a side effect, and noted it can occur outside of diabetes.
Medscape Medical News



Group CBT Does Not Maintain Weight Loss in Obese With Diabetes Group CBT Does Not Maintain Weight Loss in Obese With Diabetes

Wed, 13 Sep 2017 15:51:38 EDT

A randomized controlled trial in patients with both type 2 diabetes and obesity shows that cognitive behavior group therapy does not help maintain weight loss over 2 years.
Medscape Medical News



Gene Could Cause Missed Diabetes Diagnosis in African Americans Gene Could Cause Missed Diabetes Diagnosis in African Americans

Wed, 13 Sep 2017 15:42:29 EDT

The largest study of its kind finds a variant in G6PD gene could lead to inaccurate HbA1c results and missed type 2 diagnoses in African Americans. One in 10 black men, and one in 100 black women, could be affected.
Medscape Medical News



'Vote of Confidence for Sulfonylureas and Pioglitazone' in TOSCA IT'Vote of Confidence for Sulfonylureas and Pioglitazone' in TOSCA IT

Wed, 13 Sep 2017 14:23:26 EDT

"My bottom line is this is a vote of confidence for sulfonylureas and pioglitazone," said one expert. "You could use these data to perhaps finesse which patients you might give them to."
Medscape Medical News



InTandem3: Sotagliflozin Has Benefits and Risks in Type 1 DiabetesInTandem3: Sotagliflozin Has Benefits and Risks in Type 1 Diabetes

Wed, 13 Sep 2017 12:54:43 EDT

The largest of three phase 3 studies of the novel investigational SGLT1/SGLT2 inhibitor shows that it improves glycemic control and may reduce body weight and BP but also raises some risks, including DKA.
Medscape Medical News



Romosozumab in ARCH: Good Fracture Reduction, but CV Effects a Worry Romosozumab in ARCH: Good Fracture Reduction, but CV Effects a Worry

Wed, 13 Sep 2017 08:39:41 EDT

Results from the ARCH trial are encouraging for the anabolic drug, but experts' voice concern over cardiovascular events; for now, the drug is in regulatory limbo.
Medscape Medical News