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Latest Anemia News



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Weight Loss Surgery Increases Risk of Anemia After 10 Years
(image) Patients who underwent Roux-en-Y gastric bypass are at risk of anemia even after 10 years of the surgery. Potential adverse outcomes of Roux-en-Y gastric bypass (RYGB), such as mineral and/or vitamin deficiency, are well documented. Dan Eisenberg, M.D., M.S., of the Palo Alto Veterans Affairs Health Care System, Palo Alto, and Stanford University, Stanford, Calif., and colleagues examined the prevalence of anemia 10 years after RYGB and assessed whether postoperative bariatric follow-up influences rates of anemia....



New Gene Mutation Associated With Defective DNA Repair and Fanconi Anemia
(image) Low platelet count and unusually large red blood cells characterize a rare genetic disease by hematologic symptoms known as Fanconi anemia. Mutations in nearly 20 genes have been identified as causative for Fanconi anemia, all of which encode proteins involved in DNA repair mechanisms. The failure to repair DNA is also considered the source of increased cancer risk in individuals with Fanconi anemia. This week in the JCI, a team led by Detlev Schindler at the University of Wurzburg describes ...



Blood Test To Predict Anemia Risk Post Malaria Treatment
(image) bHighlights/b li Anemia frequently affects patients treated for severe malaria with artemisinin drugs which kills malarial parasites. /li li But the deparasitized red blood cells retain the parasite histidine-rich protein 2 (HRP2). /li li HRP2 can be measured with a rapid diagnostic dipstick test that then can be used to predict the risk for delayed hemolysis and anemia. /li/ul An estimated 3.2 billion people in 95 countries are at risk of malaria infection, and even ...



In African Schools, Malaria Control Reduces Anemia Risk
(image) Malaria is a life-threatening blood disease caused by parasites transmitted to humans through the bite of the Anopheles mosquito. Congenital malaria occurs when a mother with malaria passes on the disease to her baby at birth. New research published in BMJ Global Health suggests that schools that provide prevention education, insecticide-treated nets and antimalarial treatment, in regions where malaria is highly seasonal, could reduce the risk of schoolchildren developing anaemia and improve their cognitive performance....



New Molecule That Could Lead to New Therapies for Anemia Identified
(image) A key molecule that could lead to new therapies for anemia and other iron disorders has been identified by a research team. "Without iron, life itself wouldn't be feasible," says Barry Paw, MD, PhD. "Iron transport is very important because of the role it plays in oxygen transport in blood, key metabolic processes and DNA replication." New findings reported in Science by a multi-institutional team, including researchers from University of Illinois, Dana-Farber/Boston Children's Cancer and Blood ...



Gene Therapy Saves Life of Teenager With Sickle Cell Anemia
(image) bHighlights/b ul class="group-list punch-points" liSickle cell anemia which is an inherited blood disorder causes the aggregation of sickle-shaped red blood cells in the blood vessels, blocking blood flow./li liPrevious treatments for sickle cell anemia like hematopoietic stem cell transplant, required a patient's bone marrow to be replaced with outside donors./li liIn gene therapy, the patient's bone marrow was removed and genetically altered to compensate for the defect in the DNA responsible for sickle cell disease....



Testosterone Treatment Improves Bone Density, Anemia In Older Men
(image) bHighlights/b ul class = "group-list punch-points" li Testosterone levels decrease as men age and the effect of testosterone treatment was unknown. /li li Testosterone treatment improved bone density and anemia for men over 65 with low testosterone. /li li The treatment increased the amount of plaque buildup in coronary arteries and did not improve cognitive function. /li/ul Testosterone treatment for men over 65 improved bone density and anemia but increased the amount ...



Aplastic Anemia Patients Treated Using Bone Marrow Transplants and Chemotherapy
(image) A recent report from the Johns Hopkins Kimmel Cancer Center Report stated that they have treated 16 patients with aplastic anemia ( a rare and lethal form of bone marrow failure) by using partially matched bone marrow transplants which was followed by two high doses of a common chemotherapy drug. The report on the new transplant-chemo transplantation is published online in iBiology of Blood and Marrow Transplantation/i. The research team also said, that it is been more than a year after ...



Iron-Fortified Bars Can Help Combat Anemia
(image) bHighlights/b ul class="group-list punch-points"li Iron-deficiency anemia is the most common nutritional disorder mostly in women. /li li Iron supplement pills often have gastrointestinal side effects like constipation and are undesirable for many. /li li Daily consumption of an iron-supplement bar leads to increased hemoglobin concentrations in anemic women. /li/ul An iron supplement bar made with locally available iron-rich ingredients increased the hemoglobin and hematocrit ...



Delayed Clamping After Birth May Prevent Anemia in Children
(image) bHighlights/b ul class = "group-list punch-points" liAnaemia affects over 40% of all children under five years of age in the world. /li li Iron deficiency up to six months of age can be prevented when clamping of the umbilical cord after birth is delayed by 3 minutes./li/ul Iron deficiency up to six months of age can be prevented when clamping of the umbilical cord is delayed, according to a new study from Uppsala University, published in JAMA Pediatrics. Anaemia can impinge ...



Iron Deficiency Anemia in Kidney Disease can be Treated With Oral Ferric Citrate
(image) bHighlights/bul class="group-list punch-points"liOral ferric citrate increased hemoglobin levels in patients with chronic kidney disease. /liliThe treatment was effective in correcting anemia within 2 weeks of initiation./liliDiarrhea and constipation were the common adverse events but was manageable. /li/ul a href="http:www.medindia.net/patients/patientinfo/iron-deficiency-anemia.htm" target="_blank" class="vcontentshlink" alt="Information About Iron ...



Anemia Among African Children Offers Natural Protection Against Malaria
(image) bHighlights/b ul class="group-list punch-points" liIron deficiency anemia offers greater natural protection against blood-stage malaria infection./li liBut iron supplementation to combat anemia, reversed the protection and increased risk of Plasmodium falciparum malaria./li liThis is because Plasmodium falciparum parasite prefers young red blood cells, which is produced by iron supplementation, for their growth./li/ul Iron deficiency anemia protects children against ...



Hearing Loss is Linked to Iron Deficiency Anemia
(image) bHighlights/b ul class = "group-list punch-points" li Diagnosing and treating iron deficiency anemia may positively affect the overall health status of adults with hearing loss. /li li Understanding of the association between IDA and all types of hearing loss may help to open new possibilities for early identification and appropriate treatment. /li/ul Hearing loss and iron deficiency anemia (IDA) are associated with each other, according to a study published online by JAMA Otolaryngology-Head (and) Neck Surgery....



Signaling Pathways in the Pathogenesis of Diamond Blackfan Anemia
(image) Diamond Blackfan Anemia (DBA) is caused by a deficiency of some ribosomal proteins to properly process pre-ribosomal ribonucleic acid (RNA), which is ultimately important for the translation of the genome into functional proteins. The condition is characterized by a failure of the bone marrow to produce red blood cells, congenital abnormalities, and a predisposition to cancer. Current treatment options, including steroid treatments and chronic transfusions, can lead to significant morbidity....



Gene Therapy for Sickle Cell Anemia Using CRISPR
(image) bHighlights/bul class="group-list punch-points"liCRISPR gene editing tool is used as a gene therapy for sickle cell anemia patients./liliThe mutated gene was 'corrected' in the hematopoietic stem cells using the CRISPR tool./liliThe treated cells were found to thrive after 16 days, paving the way for better treatment modalities for sickle cell anemia. /li/ul a href="http:www.medindia.net/patients/patientinfo/sickle-cell-anemia.htm" target="_blank" class="vcontentshlink" alt="Information ...



Pre-Diabetes Detected Effectively Using Hemoglobin A1C
(image) bHighlights/bul class="group-list punch-points"liA study by Johns Hopkins Bloomberg School of Medicine tested the efficiency of prediabetes screening using hemoglobin A1C test and blood sugar test. /liliHemoglobin A1C test found to predict the risk of diabetes associated complications better than blood sugar test./liliThis study aids in consolidating evidence about the efficiency of hemoglobin A1C test in pre-diabetes testing./li/ulResearch study by Johns Hopkins Bloomberg ...



Inadequate Monitoring and Treatment of Anemia Among Patients With Ulcerative Colitis
(image) Many patients with ulcerative colitis don't receive recommended testing and treatment for the common problem of iron deficiency anemia, reports a study published in Inflammatory Bowel Diseases, official journal of the Crohn's (and) Colitis Foundation of America (CCFA). The journal is published by Wolters Kluwer. About one-third of ulcerative colitis patients with anemia are not tested for iron deficiency--and nearly one-fourth of those diagnosed with iron deficiency anemia don't receive iron replacement ...



Higher Risk Of Death Common In Stroke Patients With Anemia
(image) Anemia, a lack of red blood cells, may be linked to a higher risk of death in older adults who have had a stroke, according to new research iniJournal of the American Heart Association/i, the Open Access Journal of the American Heart Association/American Stroke Association. Anemia is common in patients with acute stroke. Both anemia and low hemoglobin levels, which are proteins in red blood cells that carry oxygen throughout the body, are also common in older people, said Phyo Myint, M.D....



Cost Effective Target Hemoglobin in Chronic Kidney Disease
(image) bHighlights/bul class="group-list punch-points"liChronic Kidney Disease (CKD) is one of the major causes of morbidity and mortality/liliCKD and anemia go hand in hand - more the kidney damage, worse is the anemia/lili10.5g/dl is the adequate hemoglobin target in CKD patients, according to a study/liliOver-treating anemia does not improve the quality of life and only increases the cost of treatment/li/ul bResearchers found that a hemoglobin level of 10.5 g/dL is enough for patients with chronic kidney disease....



Anemia Negatively Influences the Outcome of Patients With Traumatic Brain Injuries
(image) Red blood cells contain hemoglobin, a protein crucial to the delivery of oxygenated blood. Approximately half of patients hospitalized with traumatic brain injuries are anemic, revealed recent studies, but anemia's effects on the recovery of these patients is not clear. Now, researchers from the University of Missouri School of Medicine have found evidence that anemia can negatively influence the outcomes of patients with traumatic brain injuries. "More research is needed to develop treatment ...



New Function of Genes Linked to Fanconi Anemia and Cancer
(image) Fanconi anemia (FA) is an incurable blood disorder affecting about 1 in every 130,000 people caused by mutations in any of 19 FA genes. Mutations in FA genes can lead to birth defects, cognitive impairment, bone marrow failure-related blood disorders, cancers that include pediatric leukemia, premature aging, and other abnormalities. Researchers from UT Southwestern Medical Center have identified an important new function of genes in the Fanconi anemia pathway - a finding that could have implications ...



3-D Printed Biomedical Device That can Rapidly Detect Anemia
(image) Anemia is a condition in which the blood does not have enough healthy red blood cells to transport oxygen to the body's organs. It affects about two billion people worldwide, including more than half of preschool children and pregnant women in developing countries and at least 30% of children and women in industrialized nations. US researchers have developed an inexpensive prototype of a biomedical device that can detect anemia simply by running a blood sample from a finger prick under a smartphone....



Priyanka Chopra Lends Support to National Campaign Against Anemia
(image) Anemia is a condition in which there is a deficiency of red blood cells or hemoglobin in the blood. Bollywood actress Priyanka Chopra will go on a nationwide tour to spread awareness on fighting anemia among adolescents, through a short movie. The actress was in the national capital on Wednesday, December 24, 2015, to launch the nationwide Weekly Iron and Folic Acid Supplement (WISF) awareness campaign along with Health Minister J.P. Nadda. Through the initiative, free pills would be distributed ...



Indian Health Ministry and UNICEF Launches Program to Curb Anemia Among Adolescents
(image) Health ministry has revamped the ongoing Weekly Iron and Folic Acid Supplementation (WIFS) Program after the rates of anemia increased drastically in India.The program has been initiated in 2012 but it has not received much awareness in the country. Therefore, health ministry has launched the awareness on anemia and malnutrition campaign with the UNICEF represented by board actor and UN Goodwill ambassador Priyanka Chopra.Health minister JP Nadda, called it as the world's largest public health program ...



Newly Established Link Between Anemia and Mild Cognitive Impairment
(image) Anemia refers to a condition when hemoglobin 13 g/dl in men and 12 g/dl in women. In a large population-based study of randomly selected participants in Germany, researchers found that participants with anemia showed lower performances in verbal memory and executive functions. Furthermore, mild cognitive impairment (MCI) occurred almost twice more often in participants diagnosed with anemia. This study is published in the iJournal of Alzheimer's Disease/i. Because dementia is the end stage ...



Indian-American Couple to Raise Funds for Sickle Cell Anemia Research
(image) Sickle cell anemia is a hereditary disorder characterized by an abnormality in the oxygen-carrying hemoglobin molecule in red blood cells. A charity organization in Washington that is run by an Indian-origin couple will start a fund raising campaign on Saturday, September 5, 2015, to benefit sickle cell disease research in the US. Sanjay Patel said, "There are 250 million people in the world that carry the sickle cell gene. It is a very cruel disease, you just never know what is going to happen....



UNICEF Goodwill Ambassador, Actress Priyanka Chopra Emphasizes The Need To Fight Anemia
(image) A short film was released by UNICEF in which its Goodwill Ambassador Priyanka Chopra and others emphasized on the importance of stepping up fight against adolescent anemia. Adolescent anemia is regarded as a major health problem among adolescents in developing countries including India. In the film released on the occasion of World Youth Day, Chopra said, "One out of two young girls and one out of three young boys in India are anemic. Anaemia is a serious health problem not only in rural but also in the urban areas....



Patients in India With Sickle Cell Anemia Suffer Due To Insufficient Healthcare Services
(image) World Sickle Cell Day with the theme strengthening the primary health services for sickle cell patients is commemorated on June 19 every year. World Health Organization (WHO) estimates that 5% of the world's population is afflicted by genetic blood disorders like sickle cell anemia. In India, Nagpur is in the center of sickle cell belt and the health services in the city cater to patients from all over Central India. These services, however, leave a lot of scope for improvement. Maharashtra fares poorly in this regard....



Masimo's Root Monitoring System Records BP, Temperature and Hemoglobin
(image) Masimo's root patient monitoring and connectivity system that includes blood pressure monitoring from SunTech Medical and a thermometer by Welch Allyn by has won European CE mark of approval. The unit has a bright touchscreen, measures BP and body temperature in anyone from adults to neonates, and features Masimo's signature Radical-7 handheld unit for SET Measure-through Motion and Low Perfusion pulse oximetry and continuous hemoglobin monitoring, among other parameters. Instead of the ...



Assam's 600,000 Tribal Kids to be Screened This Year for Sickle Cell Anaemia
(image) In Assam, India, the union tribal affairs ministry will cover at least six lakh tribal children under its sickle cell anemia screening program within this year. Sickle cell anemia is a hereditary blood disorder that results in abnormality in hemoglobin, which carries oxygen from the lungs to the body parts. "Sickle cell anemia is highest among malaria patients. Fifty percent of the malaria cases in the country have been found to be among the tribals although they constitute only eight percent ...



Sebia Introduces Its Hemoglobin Atlas
(image) Hemoglobinopathies are inherited single-gene disorders leading to production of abnormal hemoglobin or low hemoglobin. Approximately 7% of the global population are carriers and 2.7 per 1000 conceptions are affected by these disorders. The most common hemoglobinopathies are Sickle cell anemia and thalassemia. Sebia is a market leader in manufacturing diagnostic tests for hemoglobin disorders and a href="http:www.medindia.net/bloodtest/immunology/protein_electrophoresis_serum.htm" target="_blank" ...



Low-Dose Oral Iron Supplementation Improves Hemoglobin Recovery Time After Blood Donation
(image) Among blood donors with normal hemoglobin levels, low-dose oral iron supplementation, compared with no supplementation, reduced recovery time of the post-donation decrease in hemoglobin concentration in donors with low or higher levels of ferritin (a marker of overall iron storage), revealed researchers at Institute for Transfusion Medicine, Pittsburgh. It is estimated that 25-35 percent of blood donors become iron depleted from regular blood donation. Recovery of hemoglobin to the currently ...



Deoxygenated Hemoglobin in RBCs Converts Nitrite to Nitric Oxide
(image) Researchers from Wake Forest University have shown that conversion of nitrite to nitric oxide by deoxygenated hemoglobin in red blood cells affects blood flow and clotting. It reduces platelet activation, and this action has implications in treatments to reduce clotting in pathological conditions including sickle cell disease, hypertension, heart attack and stroke.The researchers used several biophysical techniques to measure nitric oxide production from nitrite and red blood cells and examined the mechanism of nitric oxide production....



Hydroxyurea Therapy Offers Effective Disease Management of Sickle Cell Anemia
(image) Conclusive data of a key clinical trial studying the drug's efficacy show that hydroxyurea therapy offers safe and effective disease management of sickle cell anemia (SCA). And it also reduces the risk of stroke, prompting early termination. The National Heart Lung and Blood Institute (NHLBI) officials issued the announcement about one year before the study was originally scheduled to end. Going by the title TWiTCH (TCD With Transfusions Changing to Hydroxyurea), the Phase III randomized clinical trial at 25 medical centers in the U....



SiRNA Drug can Boost EPO Production by Stimulating Liver in Anemia Patients
(image) Using a small interfering RNA (siRNA) drug to stimulate natural EPO production by the liver can help avoid the risks associated with recombinant human EPO therapy for treating patients with debilitating anemia associated with reduced erythropoietin (EPO) production, a new study published in the journal Nucleic Acid Therapeutics reveals. The peer-reviewed journal is available from Mary Ann Liebert, Inc publishers/a. The article is available free on the Nucleic Acid Therapeutics website until November 16, 2014....



Key Component In Household Vinegar Could Treat Anemia
(image) Researchers at UT Southwestern Medical Center have found that giving acetate, a key component in household vinegar, to anemic mice stimulated the formation of new red blood cells. The study sought novel ways to treat anemia. Currently, the hormone erythropoietin is administered to treat anemia, but this treatment carries with it side effects such as hypertension and thrombosis (blood clotting). The new research, which was performed in mice, suggests that acetate supplements could eventually be ...



Rapid Point-of-Care Anemia Test Shows Promise
(image) New research suggests that a simple point-of-care testing device for anemia could provide more rapid diagnosis of the common blood disorder. Furthermore, it could also allow inexpensive at-home self-monitoring of persons with chronic forms of the disease. The disposable self-testing device analyzes a single droplet of blood using a chemical reagent that produces visible color changes corresponding to different levels of anemia. The basic test produces results in about 60 seconds and requires no electrical power....



Potential Treatment for Common Anemia Represented by Drug
(image) Treatment for anemia of inflammation could be possible with an experimental drug designed to help regulate the blood's iron supply, suggest results from the first human study of the treatment published online today in iBlood/i, the Journal of the American Society of Hematology. Anemia is a condition that occurs when red blood cells are in short supply or do not function properly. When an individual has anemia, the body does not get enough oxygen, since there are fewer red blood cells to ...



Risk of Recurrent Blockage of Brain Blood in Sickle Cell Anemia Children can be Reduced Through Regular Blood Transfusions
(image) A new study published in the New England Journal of Medicine suggests that providing regular blood transfusions can prevent recurrent blockage of brain blood among children with sickle cell anemia. In the United States, approximately 100,000 people, primarily African-Americans, live with sickle cell anemia, a genetic disorder in which red blood cells, which should be round, can take on abnormal, crescent-like shapes. These sickle cells are stickier than regular cells and can block blood flow, resulting in pain, organ damage and strokes....



Hemoglobin Produced by Altering Biological Events in Red Blood Cells Could Lead to Development of New Therapies for Sickle Cell Disease
(image) A new form of hemoglobin, produced by the red blood cells after researchers altered key biological events in the cells, could form the basis of new therapies for sickle cell disease as it is not affected by the inherited genetic mutations that cause the debilitating blood disorder. The novel approach uses protein-engineering techniques to force chromatin fiber, the substance of chromosomes, into looped structures that contact DNA at specific sites to preferentially activate genes that regulate hemoglobin....



Smartphone App Helps Diagnose Anemia from Selfies
(image) Selfies may now be used as a simple and effortlessly accessible tool to detect Anemia, thanks to the efforts of two medicine students of iMonash University/i. Jarrel Seah and Jennifer Tang have created Eyenaemia, a smartphone app that helps diagnose Anemia from selfies. Sources said that the app won Microsoft's 2014 Imagine World Cup and its developers werelikely to get a private meeting with none other than Bill Gates. The traditional method emof diagnosing anemia/em ...



Kidney Disease Patients may be Affected by Anemia from Common Virus
(image) A virus that is present in a latent state most people may induce or exacerbate anemia in patients with kidney disease, a new study found. The findings point to a new therapeutic target for affected individuals. Chronic kidney disease (CKD) patients and kidney transplant recipients often develop anemia, or low levels of red blood cells. This is often because they do not produce enough erythropoietin (EPO), a hormone that is made in the kidney and stimulates production of red blood cells. Lynn ...



Low Levels of Hemoglobin Associated With a Lower Risk of Health Care-Associated Infections
(image) Restricting red blood cell (RBC) transfusions among hospitalized patients to those with hemoglobin (the iron-containing protein in RBCs) measures below a certain level is associated with a lower risk of health care-associated infections. This is according to a study in the April 2 issue of iJAMA/i. Efforts to prevent health care-associated infection are among the priorities for the U.S. Department of Health and Human Services. The estimated annual direct medical costs of health care-associated infections to U....



Medtech Startup Wrig Nanosystems Launches Haemoglobin Measurement Device
(image) To help eradicate anaemia in the country, Medtech startup Wrig Nanosystems launched a first of its kind ultra-convenient haemoglobin measurement device, TrueHb Hemometer. The hemometer is compact, ultra-convenient and a portable device with 99 percent accuracy which has been validated at All India Institute of Medical Science (AIIMS). It is rechargeable and has high precision at a low price. "Currently, the availability and proximity of blood testing facilities is a challenge, globally....



Sickle Cell Trait Could be Responsible for Higher Dosing of Anemia Drugs Among African-American Dialysis Patients
(image) A new study published in the Journal of the American Society of Nephrology suggests that one of the major reasons why African Americans who are on dialysis require higher doses of an anemia medication could be due to the presence of sickle cell trait. Sickle cell trait represents the carrier state of sickle cell disease and is present in roughly 6% to 8% of African Americans. In sickle cell disease, individuals have two copies of a genetic mutation that produces an abnormal change in hemoglobin, ...



Research: Rare Cause of Anemia in Newborns is Often Overlooked
(image) Scientists from Dana-Farber/Boston Children's Cancer and Blood Disorders Center say that some babies diagnosed with and treated for a bone marrow failure disorder, called Diamond Blackfan Anemia, may actually be affected by a very rare anemia syndrome that has a different disease course and treatment. Genetic analysis of DNA from 175 patients believed to have Diamond Blackfan Anemia, identified eight that showed hallmarks of Pearson Marrow Pancreas syndrome, according to research presented ...



Scientists are No Closer to Understanding Anemia in Female Athletes
(image) Kaitlyn Patterson knew something was very wrong when her fatigue progressed to hyperventilating even during slow runs. Later on it forced her to quit high school distance running for the season. Patterson had exercise-induced iron-deficiency anemia, a common, perplexing problem among elite female athletes, especially endurance runners. Later, as a University of Michigan sophomore, she was so interested in the topic that she applied for an undergraduate research position in the lab of Peter Bodary, ...



Low Vitamin D Levels Raise Anemia Risk in Children
(image) Low levels of vitamin D increase the risk of anemia in children, finds research published in the iJournal of Pediatrics/i. The researchers caution that their results are not proof of cause and effect, but rather evidence of a complex interplay between low vitamin D levels and hemoglobin, the oxygen-binding protein in red blood cells. The investigators say several mechanisms could account for the link between vitamin D and anemia, including vitamin D's effects on red blood cell production ...



Anemia and High Altitude Increase Pneumonia in Children
(image) The leading cause of death of young children around the world is pneumonia. A study from an international group of researchers now finds that the risk of poor outcomes - including persistent pneumonia, secondary infections, organ failure or death - in children who contract pneumonia is four times higher in those who also have anemia and live at high altitudes (over 2,000 meters or about 6,500 feet). The report in the November issue of iPediatrics/i has been released online. "We know ...