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Preview: Latest Alcoholic Liver Disease News

Latest Alcoholic Liver Disease News



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Potential Emotional Factors Influence Alcohol Preference
(image) Alcohol is a drug. It is classed as a depressant, meaning that it slows down vital functions-resulting in slurred speech, unsteady movement, disturbed perceptions and an inability to react quickly. Different types of alcohol elicit different emotional responses, but spirits are most frequently associated with feelings of aggression, suggests research published in the online journal BMJ Open. To explore the potential emotional factors underpinning alcohol preference the researchers drew ...



Alcohol And Metabolic Factors Combined can Increase Liver Risk
(image) New insights into alcohol consumption and metabolic syndrome can help diagnose severe liver disease early among general population found a new study published in iHepatology/i journal. Multiple components of the metabolic syndrome and alcohol consumption at levels that are typically thought to not cause liver damage can also influence the risk. Worldwide there is an increasing burden of liver disease and liver cancer. The metabolic syndrome and heavy alcohol consumption are both associated ...



Gastric Sleeve Surgery Lowers Women's Alcohol Tolerance
(image) Women after undergoing gastric sleeve surgery need to reduce the number of alcohol drinks by half, as alcohol absorption to the bloodstream is much faster, reveals a new study. The new study was conducted by a team of researchers at the University of Illinois and Washington University School of Medicine in St. Louis. Sleeve gastrectomy, similar to another weight-loss surgery, Roux-en-Y gastric bypass (RYGB), speeds up alcohol absorption to the bloodstream. After drinking, blood alcohol ...



Scientists Discover How to Switch Liver Cancer Cell Growth
(image) Scientists have discovered how to make tiny colonies of cells grow in useful new ways inside petri dishes paving the way for testing experimental drugs in more realistic environments. The study took place at the National Institute of Standards and Technology (NIST). The research team's discoveries might help designers of miniature "lab-on-a-chip" technologies to grow three-dimensional colonies of liver cancer cells inside a chip's tiny chambers, rather than the merely two-dimensional colonies that they generally can culture now....



Coffee Consumption Lowers Risk of Liver Disease
(image) 'Looking after the liver: coffee, caffeine and lifestyle factors', a new report from the Institute for Scientific Information on Coffee (ISIC) highlights the potential role of coffee consumption in reducing the risk of liver diseases such as liver cancer and cirrhosis. Roundtable delegates including academics, media medics and representatives from national liver associations from across seven European countries, met to discuss the most recent research into coffee and liver health, and the potential ...



Smoking and Heavy Drinking Could be Linked to Aging Signs
(image) bHighlights/b liHeavy drinking and smoking may promote certain physical signs of aging/li liEarlobe creases, arcus corneae, yellow-orange plaques on the eyelids,male pattern baldness are some of the major signs of aging/li liConsistently heightened risk of looking older and developing arcus corneae, earlobe creases, and xanthelasmata among those who smoked and drank heavily could be linked/li/ul Heaving drinking and smoking can be linked to physical signs of aging, found ...



A Potential Vaccine may Prevent Liver Cancer
(image) Primary liver cancer is the second leading cause of cancer-related deaths worldwide, and its incidences and related-mortality are on the rise in the United States. There are no effective treatments or drugs in later stages of the malignancy making it deadly. An unexpected finding made by a team at the University of California San Diego School of Medicine sheds light on the development of a new strategy for prevention of liver cancer. While studying the pathogenic mechanisms of liver cancer, the ...



Ibuprofen may Treat Fetal Alcohol Spectrum Disorders
(image) bHighlights/b ul class = "group-list punch-points" liAnti-inflammatory drug such as ibuprofen can help delay harmful effects of alcohol on the baby's brain /li liIbuprofen can reduce neuroinflammation and behavioural signs of alcohol exposure in infants/li liFetal exposure to alcohol can lead to a cluster of cognitive impairment problems such as trouble learning, remembering and paying attention /li/ul Ibuprofen, an anti-inflammatory drug can delay the potentially harmful ...



Nonalcoholic Fatty Liver Disease May Up Risk of Various Cancers
(image) bHighlights/b ul class = (and) #23364;roup-list punch-points (and) #65533; liNonalcoholic fatty liver disease (NAFLD) is linked to hepatocellular carcinoma and also to cancers outside the liver like colorectal and breast cancer/li liNAFLD is the most prevalent liver disease in many countries around the world/li liNAFLD can increase the risk of liver, colorectal, and breast cancers/li/ul bNonalcoholic fatty liver disease (NAFLD),/b which is among one of the most common chronic ...



Insomnia in Young Adults Associated With Alcohol Use
(image) Frequency of alcohol intake is linked to insomnia among early adolescents, reports new study from Rutgers University-Camden research. "Parents, educators, and therapists should consider insomnia to be a risk marker for alcohol use, and alcohol use a risk marker for insomnia, among early adolescents," writes Rutgers-Camden researcher Naomi Marmorstein in the study, published recently in the journal Addictive Behaviors. Marmorstein, a professor of psychology at Rutgers-Camden, examined the ...



PEth Test Can Identify Alcohol Misuse in Critically Ill Patients
(image) PEth, a simple blood test helps in identifying alcohol misuse in critically ill hospital patients, reveals a new study. The finding is important because patients who misuse alcohol tend to have worse outcomes. If validated in further studies, the PEth test could help doctors anticipate and perhaps ward off alcohol-related complications such as organ failure and impaired healing of wounds and bones. The study, published in Alcoholism: Clinical (and) Experimental Research, included researchers from ...



Long-term Exposure to Alcohol Kills Stem Cells in the Brain
(image) Alcohol found to kill stem cells residing in adult mouse brains, reports a research team the University of Texas Medical Branch at Galveston. Brain stems cells are important in creating new nerve cells and maintaining normal cognitive function. The researchers also found that bbrain stem cells in key brain regions of adult mice respond differently to alcohol exposure, and they show for the first time that these changes are different for females and males/b. The findings are available in iStem Cell Reports/i....



Chronic Inflammation May Promote Liver Cancer
(image) Chronic liver inflammation promotes cancer by suppressing bimmunosurveillance/b, a natural defense mechanism in which it is thought the immune system suppresses cancer development, recent research at the University of California San Diego School of Medicine found. "Recent successes in cancer immunotherapy, in the form of immune checkpoint inhibitors and adoptive T cell transfer, demonstrate how activated immune cells can eradicate tumors, but until now we didn't fully appreciate immunosurveillance ...



New Targets Identified to Minimize Alcoholic Liver Disease's Ill Effects
(image) bHighlights/b ul class = "group-list punch-points" liInhibition of hepatic microRNA-34a (miR-34a) and it's expression may help reduce liver injury and liver fibrosis in ALD patients/li liChronic alcohol consumption can cause abnormal fat accumulation in liver cells (steatosis) and liver fibrosis, which can lead to hepatitis, cirrhosis, and sometimes liver cancer /li liUp-regulation of miR-34a during alcohol consumption contributes to the development of liver fibrosis during ...



Targeting Fat Hormone may be Effective in Treating Fatty Liver Disease
(image) The rising obesity epidemic has brought with it an army of maladies. Non-alcoholic fatty liver disease, in particular, is threatening to outpace many of the other obesity-linked disorders in terms of occurrence and severity. "I think in the coming decades, it's going to be a bigger problem than even diabetes," said University of Michigan cell biologist Jiandie Lin, senior author of a new study that identified a key driver of the progression to the most harmful form of the disease - non-alcoholic steatohepatitis, or NASH....



Higher Estrogen Levels Raises Alcohol Sensitivity in Brain's Reward Center
(image) Higher levels of estrogen in women increases alcohol sensitivity in the brain's reward center, reveals a new study. Led by Amy Lasek, assistant professor of psychiatry in the UIC College of Medicine, researchers found that neurons in a region of the brain called the ventral tegmental area, or VTA (also known as the "reward center"), fired most rapidly in response to alcohol when their estrogen levels were high. This response, according to their findings published online in the journal iPLOS ...



Marijuana and Alcohol Use in Teens Lessens Life Success
(image) If marijuana and alcohol are used at the same time there is a greater likelihood of negative side-effects occurring either physically or psychologically. Young adults dependent on marijuana and alcohol are less likely to achieve adult life goals. This is according to new research by UConn Health scientists presented November 5 at the American Public Health Association 2017 Annual Meeting (and) Expo. UConn Health researchers examined data from the Collaborative Study on the Genetics of Alcoholism ...



Psoriasis (PsO) Heightens Risk for Serious Liver Disease
(image) bHighlights:/b ul class = "group-list punch-points" liPsoriasis (PsO) are at higher risk for serious liver disease than patients with rheumatoid arthritis./li liPatients with psoriasis taking a systemic therapy drug like methotrexate have the highest risk./li liSystemic inflammation may play a significant role in development of liver disease in psoriasis patients./li/ul Patients with psoriasis (PsO) are at higher risk for serious liver disease than patients with rheumatoid ...



Drug and Alcohol Addicts Quit Their Habit Without Assistance
(image) For the first time, the number of Americans who have overcome serious problems with the use of alcohol or other drugs has been analyzed. More than 9 percent of those responding to their survey of a nationally representative sample of U.S. adults indicated they had previously had such a problem but no longer did, and a little more than half of them reported accomplishing this with some sort of assistance. Only 46 percent of successful respondents considered themselves to be "in recovery." "The ...



Alcohol is Potentially Detrimental to Brain Development
(image) Binge drinking involves a dangerous pattern of excessive alcohol consumption. Binge-drinking behavior as teenagers can lead to problems with alcohol and other drug dependence later on in life. That's according to researchers from the University of Adelaide, who are making advances in an emerging field of research highlighting the importance of the brain's immune system in our desire to drink alcohol. The Adelaide researchers have made a discovery that may eventually help to switch off binge-drinking ...



Drinking Wine Boost a Woman's Chances of Becoming Pregnant
(image) Alcohol consumption during pregnancy is strictly prohibited across the globe. Resveratrol found in red wine has long been linked to a host of health benefits. Resveratrol has been linked to promoting good skin, slow doing ageing and provide a dose of antioxidants to the body. Moderate red wine consumption has also been linked to promoting hair and heart health, inducing sleep and guarding against cognitive decline. Research from the Washington University School of Medicine in the US revealed ...



Poor Nutritional Status Needs to be Addressed in Patients With Liver Failure
(image) Poor nutritional status need to be addressed in patients with cirrhosis who had a liver transplant and emphasis needs to be made in screening these patients, reveals a new study. Poor nutrition is common in patients with liver failure, or cirrhosis, and it can lead to muscle wasting, weakness, fatigue, and worse outcomes before and after patients undergo liver transplantation. The new review was published in iLiver Transplantation/i. "Muscle wasting is frequently overlooked in liver ...



Alcohol Abuse in Family Linked With Teenage Dating Violence
(image) Drinking alcohol is not necessarily a problem but drinking too much can cause a range of consequences. Having a parent with an alcohol use disorder increases the risk for dating violence among teens, shows a study from the University at Buffalo Research Institute on Addictions. In addition, researchers found that the root causes of teen dating violence can be seen as early as infancy. "Although teen dating violence is typically viewed as a problem related specifically to adolescent development, ...



Herbal Remedies that Contain Aristolochic Acid Causes Liver Cancer
(image) bHighlights/b ul class = "group-list punch-points" liAristolochic acid (AA) is an herbal compound found in many traditional medicines and can cause liver cancers/li liAA containing herbs have been restricted or banned in some countries like Europe, Singapore, Taiwan and China/li liThere is a great need for creating awareness and educating the public to avoid exposure to these AA-containing herbs and remedies/li/ul bAristolochic Acids (AA)/b are natural products of some plants that are used in herbal remedies....



Cause of Rare Form of Liver Cancer Found
(image) A research team at the University of Copenhagen conducted research on mice and found that the coupling of two genes called bDnajb and Prkaca/b through a mutation causes a cancer tumour to develop in the liver. The researchers have made sure the genetic composition of the mutation in the mice is identical with the mutation found in human patients. This makes the researchers conclude that the gene mutation also leads to cancer in humans. There is no effective treatment for the cancer form found ...



Removal of Damaged Mitochondria may Help Treat Liver Cancer
(image) The mechanism of how cancer stem cells survive has been identified by a research team at Keck School of Medicine. This finding may one day lead to new therapies for a type of cancer with the highest incidence rates in the United States--Liver cancer. "Liver cancer is difficult to treat, and most patients who are diagnosed with it will die within a five-year period," said Jing-Hsiung James Ou, senior author of a new study and a professor of molecular microbiology and immunology at the Keck School of Medicine....



Drugs That Reduce Gastric Acid Secretion Can Cause Liver Disease
(image) bHighlights/b ul class = "group-list punch-points" li Drugs that block the secretion of gastric acids can increase risk of chronic liver disease. /li li Proton pump inhibitor (PPI) drugs block stomach acid secretions and relieve symptoms of frequent heartburn, acid reflux. /li li Gastric acid suppression alters specific gut bacteria in a way that promotes liver injury and progression of three types of chronic liver disease. /li/ul Proton pump inhibitor (PPI) drugs which ...



Liquid Biopsy With Tumor DNA - New Detection of Liver Cancer
(image) bHighlights:/b ul class = (and) #23364;roup-list punch-points (and) #65533; liDNA-based liquid biopsies offer quicker detection for liver cancer./li liThey are minimally invasive./li liThey represent the entire molecular picture of a patient's malignancy./li/ul A team of researchers at University of California San Diego School of Medicine and Moores Cancer Center have developed a new diagnostic and prognosis method for early detection of hepatocellular carcinoma (HCC), based on ...



New Liver Cancer Cases Increased 75% Between 1990 and 2015
(image) Liver cancer is cancer that begins in the cells of your liver. Liver cancer is among the leading causes of cancer death worldwide. A new study reports the results of the Global Burden of Disease 2015 study on primary liver cancer incidence, death and years of healthy life lost in 195 countries or territories from 1990 to 2015. The article was published by JAMA Oncology. The article by the Global Burden of Disease Liver Cancer Collaboration and corresponding author Christina Fitzmaurice, M.D....



Alcohol Aversion Drug Can Treat Chemo-resistant Lung Cancer
(image) Disulfiram, a well-known alcohol aversion drug when combined with chemotherapy can be effective in killing drug resistant lung cancer stem cells in non-small cell lung cancer (NSCLC), which is the most common type of lung cancer, reveals a new study. The findings from the scientists at Trinity College Dublin and St James's Hospital, Dublin, Ireland, have been published in the leading international journal iOncotarget./i Chemotherapy forms the backbone of many treatment plans for lung ...



Alcohol can Cause Neurological Damage Without Involving Brain's Immune System
(image) Fetal alcohol spectrum disorders (FASD) are seen in children who are exposed to alcohol while in the womb. Lately, the theory that the cells in the brain's immune system cause neurological damage is being questioned by scientists, reveals a new study. "In order to develop treatments for this condition, we must first understand how alcohol affects the developing brain," said Ania Majewska, Ph.D., an associate professor in the Department of Neuroscience at the University of Rochester Medical Center (URMC) and lead author of the study....



Mexican-Americans at a Higher Risk for Liver Cancer
(image) Mexican-Americans living in the United States demonstrated more risk factors for liver cancer than their counterparts in Mexico, according to results of a study presented at the 10th AACR Conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved. "Liver cancer incidence and mortality have been on the rise in the United States, despite a steady decline in overall cancer incidence and mortality over the past 15 years," said the study's lead author, Yvonne N....



Alcohol And Relative Diet Intake May Influence Liver Problems
(image) bHigh alcohol preferential mice did not exhibit the most serious liver injuries when placed on controlled diet/b found a new study published in iAlcohol and Alcoholism/i journal. Alcoholic liver disease is a global health burden and refers to various symptoms ranging from hepatomegaly (enlargement of the liver) and simple fatty liver, to more severe pathologies such as alcoholic steatohepatitis and hepatic cirrhosis (thickening and scarring of the liver). bIn the United States ...



Strong Alcohol Policies Help Reduce Alcohol-Involved Homicides
(image) Stronger alcohol policies, including taxes and sales restrictions, have been shown to reduce the likelihood of alcohol involvement among homicide victims, according to a new study from Boston Medical Center (BMC) and Boston University. The study, published online in the iJournal of Studies on Alcohol and Drugs/i, supports the importance of alcohol control policies to reduce violence, including homicide. Alcohol is an established risk factor for homicide perpetration and victimization. In the U....



Alcohol Use Affects Levels of Cholesterol Regulator
(image) In an analysis of the epigenomes of people and mice, researchers at Johns Hopkins Medicine and the National Institutes of Health report that drinking alcohol may induce changes to a cholesterol-regulating gene. The findings suggest that these changes to the gene, known as PCSK9, may explain at least some of the differences in how cholesterol is processed in people who drink alcohol, or may affect those taking a relatively new class of PCSK9 cholesterol-lowering drugs designed to reduce LDL cholesterol, commonly known as bad cholesterol....



Heavy Drinking Can Lower Chances of Finding a Job After College
(image) The probability of a new college graduate finding a job reduces by 10 percent when they binge drink six times a month, reveals a new study. The study conducted was according to Tel Aviv University and Cornell University research published in the iJournal of Applied Psychology./i Previous studies were unable to determine the precise effect of alcohol consumption on first-time employment. But according to the new study, each individual episode of student binge-drinking during a month-long ...



YouTube Videos Promoting 'Fun' Side of Alcohol on the Rise
(image) Alcohol is a drug. It is classed as a depressant, meaning that it slows down vital functions - resulting in slurred speech, unsteady movement, disturbed perceptions and an inability to react quickly. Turns out, many YouTube videos glorifying alcohol are being heavily viewed. Researchers looked at 137 YouTube videos that featured alcohol brands popular with underage drinkers - from beer to vodka to cognac. Together, the videos had been viewed nearly 97 million times. Most often, 40 percent of ...



Alcohol Alters Expression of Genes That Regulate Cholesterol
(image) Drinking alcohol may induce changes to a cholesterol-regulating gene. The findings of a recent study suggest that these changes to the gene, known as PCSK9, may explain at least some of the differences in how cholesterol is processed in people who drink alcohol. The research team caution that their analysis looked at and found only associations between alcohol consumption and epigenetic changes, not cause-and-effect, and that more studies are needed to demonstrate any direct link. "Small ...



Gene Therapy Aids in Treating Alcoholism
(image) A novel gene therapy discovered aids in treating alcoholism by using shRNA technology delivered, which reduces aldehyde dehydrogenase (ALDH2) expression, reveals a new study. Researchers used gene transfer to block the expression of one of the two main enzymes that break down alcohol in the liver, leading to the accumulation in liver cells of acetaldehyde, a metabolic byproduct of ethanol. The inability to metabolize acetaldehyde produces strong effects in people, such as dizziness and ...



Liver Cancer in Children Needs Better Modes Of Diagnosis
(image) Metabolic differences between hepatoblastoma subtypes, and several biomarkers that can help obtain more accurate subtyping of the disease has been identified. Hepatoblastoma is a rare pediatric liver cancer, usually diagnosed in the first three years of life. Histological methods are used to distinguish between the different subtypes of hepatoblastoma. There are many subtypes of hepatoblastoma, the two major ones being fetal and embryonal. Clinically, pure fetal cases have the best prognosis....



Brain's Immune System Linked to the Desire to Drink Alcohol
(image) The link between the brain's immunity and the motivation to drink alcohol at night has been identified by a research team at the University of Adelaide. The team was able to switch off the impulse to drink alcohol in mice by giving a drug that blocks a specific response from the immune system in the brain. The study published in the journal iBrain, Behavior and Immunity/i, this research is one of the first of its kind to show a link between the brain's immunity and the urge to drink alcohol at night....



Chronic Cell Death Promotes Liver Cancer
(image) Liver cancer occurs predominantly in patients whose liver has been damaged as a result of chronic disease. Until now it has remained in the dark how these events are linked at molecular level. An international team of scientists from the German Cancer Research Center and the University of Zurich has now shown that chronic cell death promotes the development of cancer. The more cells die, the more the remaining cells have to divide. In this process, they accumulate mutations: fertile ground for liver cancer to develop....



Alcohol Industry Misrepresenting the Link Between Alcohol and Cancer
(image) Not everyone who drinks alcohol will develop cancer. But on the whole, scientists have found that some cancers are more common in people who drink more alcohol than others. Recently scientists have claimed that in a bid to protect its profits, alcohol industry is misleading the public by downplaying and misrepresenting the link between alcohol and cancer - especially breast cancer. The researchers from the London School of Hygiene (and) Tropical Medicine with the Karolinska Institutet, Sweden ...



Alcohol During Pregnancy? A Strict No! - Fetal Alcohol Syndrome Awareness Day
(image) h2 class="all"Highlights:/h2ul class="group-list punch-points"liFetal alcohol syndrome refers to the various neurological and physical complications in the fetus associated with maternal alcohol intake./liliFetal alcohol syndrome is the most important cause of preventable mental handicap in children in the Western world./liliFetal alcohol syndrome day is observed on the 9supth/sup September annually aims to raise awareness about the dangers to the fetus ...



Does Alcohol Affect the Risk of Developing an Abdominal Aortic Aneurysm?
(image) In an analysis of published studies, lower levels of alcohol consumption were associated with a lower risk of abdominal aortic aneurysm until approximately 15 to 20 g/day, with an increasing risk thereafter. In the iBritish Journal of Surgery/i analysis, the increase in risk beyond 2 units/day was stronger in men than in women. An abdominal aortic aneurysm occurs when an area of the aorta--the main blood vessel that supplies blood to the abdomen, pelvis, and legs--becomes very large or balloons out....



Combining Substance Abuse Treatment With Regular Medical Care can Beat Opioid or Alcohol Addiction
(image) Alcohol abuse can harm your relationships, cause you to miss work, and lead to legal problems such as driving while drunk. When you abuse alcohol, you continue to drink even though you know your drinking is causing problems. Combining substance abuse treatment with regular medical care can successfully treat people with opioid or alcohol addiction. According to researchers, this model can be a lower-cost and more-accessible way to treat opioid addiction than expanding the nation's supply of specialty care clinics....



Binge Drinking in Early 20s can Alter Brain Functioning
(image) Binge drinking is the practice of consuming large quantities of alcohol in a single session, usually defined as five or more drinks at one time for a man, or four or more drinks at one time for a woman. Moderate drinking is fine, but beware, binge drinking in early 20's can alter your brain functioning, especially for men. According to researchers, brain functions in young men and women, aged 23 to 28, are changed by long-term alcohol use, but that these changes are significantly different in men and women....



Alcohol Consumption Alters Brain Functioning Differently in Young Men and Women
(image) Many people start to drink alcohol during adolescence and young adulthood. Long-term alcohol consumption may alter brain functioning differently in young men and women, reveals a new study. This indicates not only that young people might be at increased risk of long-term harm from alcohol use, but also that the risks are probably different in men and women, with men possibly more at risk. This work is presented at the ECNP meeting in Paris. A Finnish research group worked with 11 young men ...



Enzyme Produced in the Liver Can Treat Fatty Liver Disease
(image) Increased production of the enzyme DPP4 by the liver promotes an increase in body fat, the development of non-alcoholic fatty liver disease and insulin resistance, reveals a new study. "In combination with our observations from additional human and cell studies, these results indicate that increased DPP4 production by the liver is the cause rather than the consequence of a fatty liver and insulin resistance," says the head of the study, Annette Schurmann from the German Institute for Human ...



Early Detection of Liver Cancer Possible With Rapid Home Blood Test
(image) bHighlights/b: ul class="group-list punch-points"liLiver (hepatocellular) cancer is a leading cause of cancer-related deaths worldwide; in 2015 alone 788000 persons died due to liver cancer according to a World Health Organization (WHO) estimate/li/ul ul class="group-list"liEarly diagnosis and treatment remains a challenge as the disease does not become symptomatic until the advanced stages/li/ul ul class="group-list"liNew rapid and ...