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Preview: Latest Alcoholic Liver Disease News

Latest Alcoholic Liver Disease News



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Split Liver Transplantation in Children can Save More Lives
(image) Alternatives to whole liver transplants for children can increase organ supply, better use of those organs and gives a chance to save more lives. In a new Johns Hopkins study of patient and graft survival trends for pediatric liver transplant recipients between 2002 and 2015, researchers found that outcomes for alternatives to whole liver transplantation (WLT), such as splitting a liver for two recipients or using a part of a liver from a living donor, have improved significantly. The report ...



Neurotransmitter Plays a Role in Alcohol Cravings
(image) Neurotransmitter glutamate plays a role in some alcohol craving, shows a study on neurochemical changes associated with alcohol addiction led by Indiana University. The research team suggests that targeting glutamate levels in the brain may allow to develop new treatments for alcoholism and other forms of addiction Alcohol dependence and alcohol use disorders occur in about 30 percent of all Americans, taking a severe toll on people's lives, as well as on the health care system and economy. ...



Marketing Lower Strength Alcohol can Curb Drinking Appetite
(image) Drinking habits can be curbed if the main marketing messages promote lower strength alcohol products as a substitute for higher strength products rather than an extra which can be used on all occasions finds a new study. The findings of this study are published in the Journal of IBMC Public Health/I. Wines and beers are some products that have lower alcohol content. These products are not actively marketed as an alternative to regular strength alcohol products. A research team led by the ...



Public Consider Alcohol More Harmful Than Marijuana
(image) Younger people are more likely to consider alcohol more harmful to a person's health than marijuana, shows study published in iPreventive Medicine/i. The study, led by a research team at RTI International, surveyed more than 1,900 adults in Oregon prior to the legalization of marijuana in the state and found that more than half (52.5%) consider alcohol to be more harmful than marijuana while few (7.5%) believe marijuana is more harmful to a person's health. Nearly 6 in 10 Democrats (57.9%), Independents (56....



US Death Rates from Alcohol Abuse, Drugs and Suicides, on the Rise
(image) Drug abuse, alcohol abuse and suicides are contributing to an alarming drop in US life expectancy, shows study. Middle-aged white Americans and rural communities are particularly affected, warn experts. The study is published in iThe BMJ today/i. Steven Woolf at Virginia Commonwealth University and Laudan Aron at the Urban Institute in Washington DC, argue that the ideal of the "American Dream" is increasingly out of reach as social mobility declines, and fewer children face a better future than their parents....



Ultrasound With Blood Test Boosts Detection of Liver Cancer
(image) bHighlights:/b ul class = "group-list punch-points" liCombining ultrasound imaging with blood test boosts detection of liver cancer in patients with cirrhosis./li liCombination of these two tests yields better detection outcome than ultrasound alone./li liAbdominal ultrasound is traditionally used for liver cancer screening./li/ul bBenefits of a combination of ultrasound and blood test in liver cancer screening/b Detection of liver cancer in patients with cirrhosis ...



Novel Drug can Reverse Brain Deficits caused by Alcohol
(image) A new drug identified can help reboot the brain and reverse the damaging effects caused by heavy alcohol consumption. Queensland University of Technology (QUT) researchers conducted their studies in adult mice show that two weeks of daily treatment with the drug tandospirone reversed the effects of 15 weeks of binge-like alcohol consumption on neurogenesis - the ability of the brain to grow and replace neurons (brain cells). The findings have been published in iScientific Reports./iul ...



Fetal Alcohol Spectrum Disorders Often Left Unnoticed in Kids
(image) Fetal alcohol spectrum disorders (FASD) affect 1 to 5% of the children across four U.S. Communities. A study of more than 6,000 first-graders found that a significant number of the children have fetal alcohol spectrum disorders (FASD), which represent more accurate prevalence estimates of FASD among general U.S. communities than prior research. Previous FASD estimates were based on smaller study populations and did not reflect the overall U.S. population. FASD is an umbrella term for a range ...



Fetal Alcohol Exposure Increasing Among US Population
(image) Fetal alcohol spectrum disorders (FASD) were found to be more prevalent than before among the general population of the US. The study was conducted by a research team at University of California San Diego School of Medicine and was published online in the iJournal of the American Medical Association./i More than 6,000 first-graders in the Pacific Southwest, Midwest, Rocky Mountain and Southeast regions of the U.S. were evaluated. Researchers found that one to 5 percent of the children were determined to have FASD....



New Way to Kill Liver Cancer
(image) A new two-step process helps kill liver cancer cells and inhibit tumor growth, shows research team from the University of Delaware and the University of Illinois at Chicago. The first step involves silencing a key cellular enzyme, and then adding a powerful drug. The study is published in iNature Communications/i. This research could accelerate the development of new treatments for liver cancer, which is currently difficult to cure. Often surgery is not an option for liver cancer, and the available drugs are only modestly effective....



Symptoms of Alcoholism Make It Difficult to Take the Drug That Treats Alcoholism
(image) Symptoms of alcoholism make it difficult for some people to regularly take the drug naltrexone, which could help treat their disease, according to a new study by Oregon State. The findings are published in the iAnnals of Behavioral Medicine/i. The finding helps researchers better understand how to intervene with patients to improve the effectiveness of the medication, said Sarah Dermody, an assistant professor in the School of Psychological Science in OSU's College of Liberal Arts. "The ...



Moderate Alcohol Consumption may Damage Brain
(image) bHighlights:/b ul class = "group-list punch-points" liAlcohol consumption, even at a moderate level is associated with risk of adverse damage in brain structure and function./li liIt is associated with cognitive decline (i.e. decline in memory and thinking skills)./li liThe hippocampus (part of the brain associated with memory and reasoning) may shrink due to alcohol consumption./li/ul The harmful effects of alcohol on the body has been an area of interest for researchers in the past and present....



Health Benefits of Low Doses of Alcohol Consumption:Study
(image) Low doses of alcohol may tamp down inflammation and help the brain clear away toxins, finds new research. While excessive consumption of alcohol is a well-documented health hazard, the new study, published in the journal Scientific Reports, points to the health benefits of low doses of alcohol. "Prolonged intake of excessive amounts of ethanol is known to have adverse effects on the central nervous system," said lead author of the study Maiken Nedergaard from the University of Rochester Medical Center (URMC) in the US....



Liver Cancer Mortality Rates Nearly Double Since the 1990s
(image) Over the last two decades, liver cancer mortality rates have increased by 80%, making it one of the fastest-growing causes of cancer deaths worldwide. According to the Global Burden of Disease Study, the most comprehensive worldwide observational epidemiological study to date, 830,000 people died as a result of the disease in 2016 compared to 464,000 people in 1990.1 This makes liver cancer the second leading cause of cancer deaths worldwide, after lung cancer. Primary liver cancer, the most ...



Parental Provision of Alcohol may Not Cut Risky Drinking
(image) Adolescents' alcohol consumption is the leading factor for death and disability in teenagers globally. You may be wrong, if you think that sharing a peg with your teenaged son or daughter may teach them how to deal with alcohol responsibly and protect them from engaging in heavy drinking. Instead, the practice may lead them to addiction, researchers have warned. Alcohol consumption among teens is of concern as this is when alcohol-use disorders are most likely to develop, the researchers said....



Sugar Tax on Soft Drinks may Increase Alcohol Consumption
(image) People drink to socialize, celebrate, and relax. A sugar tax levied on soft drinks might have the unintended consequence of driving up alcohol consumption, but the picture is mixed, finds new research. The study got published online in the Journal of Epidemiology (and) Community Health. As many alcoholic drinks contain similar or greater amounts of sugar (43 kcals/100 ml for beer; 85 kcals for wine; 40 kcals for cola) and have other well known harms, a more nuanced approach across a range of beverages ...



Alcohol Consumption in Late Adolescence can lead to Chronic Liver Disease Later on
(image) bHighlights/b ul class="group-list punch-points" liDrinking during late adolescence could be the first step towards liver problems in later life./li liThe risk is dose-dependent with no threshold effect and is more pronounced in men consuming two drinks per day, about 20 grams or more./li liAlthough there is no approved treatment, alcohol-related liver disease is theoretically 100% preventable./li/ul How much you drink in your late teens can predict the risk of cirrhosis later in life, finds a new study....



Alcohol Consumption Increases the Risk of Cancer
(image) bHighlights:/bul class="group-list punch-points"liDrinking alcohol causes permanent DNA damage to blood stem cells thereby increasing cancer risk./liliThe genetic damage is caused by acetaldehyde, a harmful chemical produced when the body processes alcohol./liliStudy shows a strong link between consumption of alcohol and the increased risk for 7 types of cancer including breast and bowel./li/ulWhile alcohol consumption in general is associated with several health risks ...



New Guidelines Help Physicians Improve Diagnosis of Liver Disease
(image) New guidelines developed help improve the use of liver blood tests in patients with liver disease. These guidelines can also prevent unnecessary repetition of tests, reveals a new study. The study was led by experts at the University of Birmingham and the recommendations were published in iGut/i. While the number of deaths from other common conditions is falling in the UK, those due to liver disease have been increasing dramatically, with a 400 percent increase in death rates between 1970 and 2010....



Alcohol Usage by Rural Middle School Students can be Reduced by Learning Aids
(image) The increased alcohol usage that occurs during the middle school years can be reduced when cooperative learning takes place, reveals a new study. Adolescents' use of alcohol is a risk factor for educational problems, diminished work capacity, disease, and later substance abuse and dependence. Many alcohol-prevention programs exist, but research has generally found their efficacy to be limited. In addition, these programs generally require schools to give up instructional time, which can negatively affect student achievement....



Alcosynth may replace Traditional Alcohol with Side Effects
(image) A synthetic alcohol product called alcosynth may replace real alcohol drinks within next 10 or 20 years, believe the top scientists. You can enjoy your favorite wine, cocktail or beer now as they believe alcosynth will become a preferred drink as it may not have real alcohol side effects such as hangover, etc. "Man-made liquor may have the same positive intoxicating effect on us, but won't harm our health," said the professor David Nutt, a former government drugs adviser of Imperial College London....



Blocking A Protein That Stimulates Fat Synthesis May Help Treat Liver Cancer
(image) The protein mTOR stimulates the production of lipids in liver tumors to satisfy the increased nutrient turnover and energy needs of cancer cells among other functions. Lipid, also known as fat, is an optimal energy source and an important cell component. Much is required for the rapid and uncontrolled growth of cancer cells. bLiver Cancer/b In Switzerland, about 650 new cases of liver cancer are diagnosed every year. The incidence of the malignant and aggressive liver cell carcinoma has ...



Liver of an Amphibian May be Used to Treat Cirrhosis
(image) The unique bliver function/b of a South American amphibian, bSiphonops annulatus/b, could pave the way to finding a cure to the devastating liver condition bcirrhosis/b. Research at the University of Surrey (UK), the Federal University of Sao Paulo and the Butantan Institute in Brazil used an innovative 3D liver cell examination to explore the liver function of this snake-like amphibian. During an in-depth examination, it was found that the liver of Siphonops annulatus produces blood ...



Toxicity of Alcohol Causes Changes in Skin Especially in Women
(image) Alcohol consumption can cause numerous diseases and health risks; adding on to the list is its effect on the skin. According to the research, consuming over 14 units of alcohol causes toxicity and immediate harm to a woman's facial skin that is visible the next morning. For women, 14 units of alcohol per week are considered healthy. The scientists found that while the hangover can subside after 24 hours, the effects on the skin for a woman aged 40 can last 28 days. Younger women bounce ...



Fetal Alcohol Syndrome Linked to Lithium Chloride
(image) New experiments in mice show that a single dose of lithium chloride, a drug used to treat bipolar disease and aggression, blocks the sleep disturbances, memory loss, and learning problems tied to fetal alcohol syndrome. Published in the journal Neuroscience online Nov. 26, and led by researchers at NYU School of Medicine, the new study found that giving the drug to newborn mice 15 minutes after "binge" alcohol consumption eliminated the hyperactivity and sleep deficits seen when rodents exposed to alcohol became adults....



How to Tackle Problems Associated With Alcohol Consumption?
(image) People drink to socialize, celebrate, and relax. Countries with populations that value autonomy and harmony tend to have higher average levels of alcohol consumption than countries with more traditional values, such as hierarchy and being part of a collective. This new research finding, published in open-access journal Frontiers in Psychology, may have important implications for international public health organizations aiming to tackle problems associated with alcohol consumption. Understanding ...



Potential Emotional Factors Influence Alcohol Preference
(image) Alcohol is a drug. It is classed as a depressant, meaning that it slows down vital functions-resulting in slurred speech, unsteady movement, disturbed perceptions and an inability to react quickly. Different types of alcohol elicit different emotional responses, but spirits are most frequently associated with feelings of aggression, suggests research published in the online journal BMJ Open. To explore the potential emotional factors underpinning alcohol preference the researchers drew ...



Alcohol And Metabolic Factors Combined can Increase Liver Risk
(image) New insights into alcohol consumption and metabolic syndrome can help diagnose severe liver disease early among general population found a new study published in iHepatology/i journal. Multiple components of the metabolic syndrome and alcohol consumption at levels that are typically thought to not cause liver damage can also influence the risk. Worldwide there is an increasing burden of liver disease and liver cancer. The metabolic syndrome and heavy alcohol consumption are both associated ...



Gastric Sleeve Surgery Lowers Women's Alcohol Tolerance
(image) Women after undergoing gastric sleeve surgery need to reduce the number of alcohol drinks by half, as alcohol absorption to the bloodstream is much faster, reveals a new study. The new study was conducted by a team of researchers at the University of Illinois and Washington University School of Medicine in St. Louis. Sleeve gastrectomy, similar to another weight-loss surgery, Roux-en-Y gastric bypass (RYGB), speeds up alcohol absorption to the bloodstream. After drinking, blood alcohol ...



Scientists Discover How to Switch Liver Cancer Cell Growth
(image) Scientists have discovered how to make tiny colonies of cells grow in useful new ways inside petri dishes paving the way for testing experimental drugs in more realistic environments. The study took place at the National Institute of Standards and Technology (NIST). The research team's discoveries might help designers of miniature "lab-on-a-chip" technologies to grow three-dimensional colonies of liver cancer cells inside a chip's tiny chambers, rather than the merely two-dimensional colonies that they generally can culture now....



Coffee Consumption Lowers Risk of Liver Disease
(image) 'Looking after the liver: coffee, caffeine and lifestyle factors', a new report from the Institute for Scientific Information on Coffee (ISIC) highlights the potential role of coffee consumption in reducing the risk of liver diseases such as liver cancer and cirrhosis. Roundtable delegates including academics, media medics and representatives from national liver associations from across seven European countries, met to discuss the most recent research into coffee and liver health, and the potential ...



Smoking and Heavy Drinking Could be Linked to Aging Signs
(image) bHighlights/b liHeavy drinking and smoking may promote certain physical signs of aging/li liEarlobe creases, arcus corneae, yellow-orange plaques on the eyelids, male pattern baldness are some of the major signs of aging/li liConsistently heightened risk of looking older and developing arcus corneae, earlobe creases, and xanthelasmata among those who smoked and drank heavily could be linked/li/ul Heaving drinking and smoking can be linked to physical signs of aging, found ...



A Potential Vaccine may Prevent Liver Cancer
(image) Primary liver cancer is the second leading cause of cancer-related deaths worldwide, and its incidences and related-mortality are on the rise in the United States. There are no effective treatments or drugs in later stages of the malignancy making it deadly. An unexpected finding made by a team at the University of California San Diego School of Medicine sheds light on the development of a new strategy for prevention of liver cancer. While studying the pathogenic mechanisms of liver cancer, the ...



Ibuprofen may Treat Fetal Alcohol Spectrum Disorders
(image) bHighlights/b ul class = "group-list punch-points" liAnti-inflammatory drug such as ibuprofen can help delay harmful effects of alcohol on the baby's brain /li liIbuprofen can reduce neuroinflammation and behavioural signs of alcohol exposure in infants/li liFetal exposure to alcohol can lead to a cluster of cognitive impairment problems such as trouble learning, remembering and paying attention /li/ul Ibuprofen, an anti-inflammatory drug can delay the potentially harmful ...



Nonalcoholic Fatty Liver Disease May Up Risk of Various Cancers
(image) bHighlights/b ul class = group-list punch-points liNonalcoholic fatty liver disease (NAFLD) is linked to hepatocellular carcinoma and also to cancers outside the liver like colorectal and breast cancer/li liNAFLD is the most prevalent liver disease in many countries around the world/li liNAFLD can increase the risk of liver, colorectal, and breast cancers/li/ul bNonalcoholic fatty liver disease (NAFLD),/b which is among one of the most common chronic liver diseases ...



Insomnia in Young Adults Associated With Alcohol Use
(image) Frequency of alcohol intake is linked to insomnia among early adolescents, reports new study from Rutgers University-Camden research. "Parents, educators, and therapists should consider insomnia to be a risk marker for alcohol use, and alcohol use a risk marker for insomnia, among early adolescents," writes Rutgers-Camden researcher Naomi Marmorstein in the study, published recently in the journal Addictive Behaviors. Marmorstein, a professor of psychology at Rutgers-Camden, examined the ...



PEth Test Can Identify Alcohol Misuse in Critically Ill Patients
(image) PEth, a simple blood test helps in identifying alcohol misuse in critically ill hospital patients, reveals a new study. The finding is important because patients who misuse alcohol tend to have worse outcomes. If validated in further studies, the PEth test could help doctors anticipate and perhaps ward off alcohol-related complications such as organ failure and impaired healing of wounds and bones. The study, published in Alcoholism: Clinical (and) Experimental Research, included researchers from ...



Long-term Exposure to Alcohol Kills Stem Cells in the Brain
(image) Alcohol found to kill stem cells residing in adult mouse brains, reports a research team the University of Texas Medical Branch at Galveston. Brain stems cells are important in creating new nerve cells and maintaining normal cognitive function. The researchers also found that bbrain stem cells in key brain regions of adult mice respond differently to alcohol exposure, and they show for the first time that these changes are different for females and males/b. The findings are available in iStem Cell Reports/i....



Chronic Inflammation May Promote Liver Cancer
(image) Chronic liver inflammation promotes cancer by suppressing bimmunosurveillance/b, a natural defense mechanism in which it is thought the immune system suppresses cancer development, recent research at the University of California San Diego School of Medicine found. "Recent successes in cancer immunotherapy, in the form of immune checkpoint inhibitors and adoptive T cell transfer, demonstrate how activated immune cells can eradicate tumors, but until now we didn't fully appreciate immunosurveillance ...



New Targets Identified to Minimize Alcoholic Liver Disease's Ill Effects
(image) bHighlights/b ul class = "group-list punch-points" liInhibition of hepatic microRNA-34a (miR-34a) and it's expression may help reduce liver injury and liver fibrosis in ALD patients/li liChronic alcohol consumption can cause abnormal fat accumulation in liver cells (steatosis) and liver fibrosis, which can lead to hepatitis, cirrhosis, and sometimes liver cancer /li liUp-regulation of miR-34a during alcohol consumption contributes to the development of liver fibrosis during ...



Targeting Fat Hormone may be Effective in Treating Fatty Liver Disease
(image) The rising obesity epidemic has brought with it an army of maladies. Non-alcoholic fatty liver disease, in particular, is threatening to outpace many of the other obesity-linked disorders in terms of occurrence and severity. "I think in the coming decades, it's going to be a bigger problem than even diabetes," said University of Michigan cell biologist Jiandie Lin, senior author of a new study that identified a key driver of the progression to the most harmful form of the disease - non-alcoholic steatohepatitis, or NASH....



Higher Estrogen Levels Raises Alcohol Sensitivity in Brain's Reward Center
(image) Higher levels of estrogen in women increases alcohol sensitivity in the brain's reward center, reveals a new study. Led by Amy Lasek, assistant professor of psychiatry in the UIC College of Medicine, researchers found that neurons in a region of the brain called the ventral tegmental area, or VTA (also known as the "reward center"), fired most rapidly in response to alcohol when their estrogen levels were high. This response, according to their findings published online in the journal iPLOS ...



Marijuana and Alcohol Use in Teens Lessens Life Success
(image) If marijuana and alcohol are used at the same time there is a greater likelihood of negative side-effects occurring either physically or psychologically. Young adults dependent on marijuana and alcohol are less likely to achieve adult life goals. This is according to new research by UConn Health scientists presented November 5 at the American Public Health Association 2017 Annual Meeting (and) Expo. UConn Health researchers examined data from the Collaborative Study on the Genetics of Alcoholism ...



Psoriasis (PsO) Heightens Risk for Serious Liver Disease
(image) bHighlights:/b ul class = "group-list punch-points" liPsoriasis (PsO) are at higher risk for serious liver disease than patients with rheumatoid arthritis./li liPatients with psoriasis taking a systemic therapy drug like methotrexate have the highest risk./li liSystemic inflammation may play a significant role in development of liver disease in psoriasis patients./li/ul Patients with psoriasis (PsO) are at higher risk for serious liver disease than patients with rheumatoid ...



Drug and Alcohol Addicts Quit Their Habit Without Assistance
(image) For the first time, the number of Americans who have overcome serious problems with the use of alcohol or other drugs has been analyzed. More than 9 percent of those responding to their survey of a nationally representative sample of U.S. adults indicated they had previously had such a problem but no longer did, and a little more than half of them reported accomplishing this with some sort of assistance. Only 46 percent of successful respondents considered themselves to be "in recovery." "The ...



Alcohol is Potentially Detrimental to Brain Development
(image) Binge drinking involves a dangerous pattern of excessive alcohol consumption. Binge-drinking behavior as teenagers can lead to problems with alcohol and other drug dependence later on in life. That's according to researchers from the University of Adelaide, who are making advances in an emerging field of research highlighting the importance of the brain's immune system in our desire to drink alcohol. The Adelaide researchers have made a discovery that may eventually help to switch off binge-drinking ...



Drinking Wine Boost a Woman's Chances of Becoming Pregnant
(image) Alcohol consumption during pregnancy is strictly prohibited across the globe. Resveratrol found in red wine has long been linked to a host of health benefits. Resveratrol has been linked to promoting good skin, slow doing ageing and provide a dose of antioxidants to the body. Moderate red wine consumption has also been linked to promoting hair and heart health, inducing sleep and guarding against cognitive decline. Research from the Washington University School of Medicine in the US revealed ...



Poor Nutritional Status Needs to be Addressed in Patients With Liver Failure
(image) Poor nutritional status need to be addressed in patients with cirrhosis who had a liver transplant and emphasis needs to be made in screening these patients, reveals a new study. Poor nutrition is common in patients with liver failure, or cirrhosis, and it can lead to muscle wasting, weakness, fatigue, and worse outcomes before and after patients undergo liver transplantation. The new review was published in iLiver Transplantation/i. "Muscle wasting is frequently overlooked in liver ...



Alcohol Abuse in Family Linked With Teenage Dating Violence
(image) Drinking alcohol is not necessarily a problem but drinking too much can cause a range of consequences. Having a parent with an alcohol use disorder increases the risk for dating violence among teens, shows a study from the University at Buffalo Research Institute on Addictions. In addition, researchers found that the root causes of teen dating violence can be seen as early as infancy. "Although teen dating violence is typically viewed as a problem related specifically to adolescent development, ...



Herbal Remedies that Contain Aristolochic Acid Causes Liver Cancer
(image) bHighlights/b ul class = "group-list punch-points" liAristolochic acid (AA) is an herbal compound found in many traditional medicines and can cause liver cancers/li liAA containing herbs have been restricted or banned in some countries like Europe, Singapore, Taiwan and China/li liThere is a great need for creating awareness and educating the public to avoid exposure to these AA-containing herbs and remedies/li/ul bAristolochic Acids (AA)/b are natural products of some plants that are used in herbal remedies....