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Comments on: Your Inner Blob





Last Build Date: Mon, 04 Feb 2013 17:13:44 +0000

 



By: Jo

Wed, 10 Jun 2009 19:41:29 +0000

Such a strange thing, to be informed of what my own cells are up to. All this activity going on, each one its own little entity going about its business, and collectively they are somehow 'me'. Life is fascinating.



By: Nike Kobe IV

Wed, 10 Jun 2009 14:49:36 +0000

Another point of added information I thought of while reading the last few paragraphs of your article was a recent seminar I saw by Scott A.



By: Kris

Wed, 10 Jun 2009 03:05:32 +0000

Great article Carl! I instantly thought of my housemate - Chi Pak- who has a wonderful article in Nature Neurosciecne http://www.nature.com/nrn/journal/v9/n2/abs/nrn2236.html explaining the different actin binding proteins/ depolymerizing factors that facilitate treadmilling in different ways. I did a rotation in Dr. James Bamburg's Lab (where Chi works) at Colorado State and man did I get a large does of ADF/Cofilin. It was great fun and I learned a lot. Another point of added information I thought of while reading the last few paragraphs of your article was a recent seminar I saw by Scott A. Weed PhD. he is researching "invadopodia" the cell protrusions that invade surrounding tissue during metastasis. He mentioned some specific compounds that are in phase 2 trials as anti-cancer that specifically target the moving "invadopdia" but leave the background cytoskeletons alone. The title of his talk was "Regulation of Cytoskeletal signaling pathways in tumor cell invasion" hope this gives you and your readers some worthy extra thoughts to ponder. Cheers -Kris



By: John S. Wilkins

Wed, 10 Jun 2009 00:35:25 +0000

I haven't read it yet, but I bet you're actin on inside information...