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Nature Biotechnology



Covering the science and business of biotechnology.



 



Wanted: biotech for an aging population

2017-07-12

Digital medicine's extraordinary ability to communicate with patients, especially in under-served communities, could help reorient the biotech industry to better address aging and its associated diseases.
























An emerging model for life sciences commercialization

2017-07-12

There are challenges in transplanting the US–European technology transfer model to emerging economies.















Public biotech in 2016—the numbers

2017-07-12

The anticipated decline in the biotech industry's ability to raise capital from public investors and an accompanying slump in biotech markets materialized in 2016, but all is not gloom and doom.



CRISPR–Cas9 claim sets and the potential to stifle innovation

2017-07-12

Extremely broad claims surrounding Cas9 nucleases have the potential to stifle innovation in the field of genome editing.






Single-cell genomics for the masses

2017-07-12

Microbial communities are rapidly sequenced at the single-cell level using droplet microfluidics.



Algal oil productivity gets a fat bonus

2017-07-12

Partitioning of carbon to lipids is engineered to improve oil accumulation in an industrial alga.



Research Highlights

2017-07-12







Single-cell genome sequencing at ultra-high-throughput with microfluidic droplet barcoding

2017-05-29

More than 50,000 single-cell genomes are sequenced in a single run using droplet barcoding.



Lipid production in Nannochloropsis gaditana is doubled by decreasing expression of a single transcriptional regulator

2017-06-19

Lipid production in the oleaginous microalga Nannocholoropsis gaditana is doubled by decreasing the expression of a transcriptional regulator identified through a CRISPR–Cas9 reverse-genetics approach.



Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation

2017-05-29

An engineered commensal E. coli strain can function as a living diagnostic for a marker of inflammation in the murine gut for 200 days.



Guided self-organization and cortical plate formation in human brain organoids

2017-05-31

Engineering human brain organoids with floating scaffolds enhances the maturity and reproducibility of cortical tissue structure.



Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site

2017-06-12

A method to target trimeric membrane proteins by designing geometrically matched trimeric protein binders is demonstrated for the influenza-virus glycoprotein hemagglutinin.



Digital-to-biological converter for on-demand production of biologics

2017-05-29

Sequence information is converted into nucleic acids, proteins and phage particles without human intervention to enable on-demand bio-manufacturing.



1,003 reference genomes of bacterial and archaeal isolates expand coverage of the tree of life

2017-06-12

Metagenomic and microbial sequence data are made easier to interpret with the addition of 1,003 genomes to the Genomic Encyclopedia of Bacteria and Archaea.



Unlocking Big Data for better health

2017-07-12

As the volume of biomedical data being created grows, so does the need for data analytics training for life science researchers.



People

2017-07-12