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Nature Biotechnology journal featuring biotechnology articles and science research papers of commercial interest in pharmaceutical, medical, and environmental sciences.



 



Off the grid

2016-09-08

The rapid growth of private clinics touting unproven stem cell therapies warrants increased regulatory scrutiny and better tracking of patient outcomes.






























A spark at the periphery

2016-09-08

Electroceutical devices that stimulate the peripheral nervous system come to the fore. Emily Waltz reports.



Where the bodies lie

2016-09-08

Some suggestions for avoiding common mistakes made in life sciences startups.









Which patent and where? Why international patent transparency by companies is needed for medicines

2016-09-08

A common method for determining the patent status of medicines internationally is highly imprecise and complicates medicine access by obscuring the true medicine patent landscape for policymakers and procurement officers.






Super-resolution microscopy writ large

2016-09-08

Improved expansion microscopy provides a super-resolution method that is accessible to any laboratory with a fluorescence microscope.



Precision medicine for autoimmune disease

2016-09-08

An antigen-specific cell therapy for autoimmune disease avoids compromising immunity as a whole.



Research Highlights

2016-09-08







Applications of CRISPR technologies in research and beyond

2016-09-08

The unique capabilities of CRISPR technologies have enabled a broad range of applications in biomedicine and agriculture.



Systematic improvement of amplicon marker gene methods for increased accuracy in microbiome studies

2016-07-25

Sources of error and bias in PCR amplification of microbial samples for 16S rRNA gene sequencing are systematically evaluated, and best-practice recommendations for reliable amplification are made.



Genetic improvement of tomato by targeted control of fruit softening

2016-07-25

Softening in tomatoes is uncoupled from ripening by silencing a pectate lyase, thereby identifying a route to engineering (or breeding) tomatoes with better shelf life and flavor.



Co-ChIP enables genome-wide mapping of histone mark co-occurrence at single-molecule resolution

2016-07-25

Co-ChIP, a method for measuring the genome-wide co-occurrence of histone marks, sheds light on the complexity of the histone code.



Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq

2016-08-01

Oncogenic driver mutations are identified in single cells by a transposon-based sequencing method.



Multiplexed and scalable super-resolution imaging of three-dimensional protein localization in size-adjustable tissues

2016-07-25

Protease-free expansion of organ-size tissue enables multiplexed super-resolution imaging of protein organization from the tissue-wide scale down through the nanoscale.



Engineered non-Mendelian inheritance of entire parental genomes in C. elegans

2016-08-01

Mendelian inheritance is abolished in C. elegans to create worms that are a genetic clone of one grandparent.



Protein-retention expansion microscopy of cells and tissues labeled using standard fluorescent proteins and antibodies

2016-07-04

Improved expansion microscopy method preserves signal from fluorescent proteins and antibodies using off-the-shelf reagents.



A survival guide for interdisciplinary PhD students

2016-09-08

Interdisciplinary studies come with high risk, but the prospects of both advancing science and pushing forward one's professional career make for high rewards.



People

2016-09-08