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Bacteria stab amoebae with daggers

Tue, 22 Aug 2017 11:02:36 +0200

Researchers from ETH Zurich and the University of Vienna have discovered a type of bacteria that uses tiny daggers to prevent itself from being eaten by amoebae. The scientists also resolved the three-dimensional structure of the mechanism that allows the micro-daggers to be shot quickly. Bacteria h...

ACHEMA 2018: Great Expectations for the World Forum of the Process Industries

Tue, 22 Aug 2017 02:00:00 +0200

Some 9 months before the start there are unmistakable signs that ACHEMA 2018 will be a crowd-puller. More than 2700 exhibitors from all around the globe have already booked a stand at this leading show for the process industries in Frankfurt am Main. From 11 to 15 June 2018 they will be showcasing t...

Nanomaterial wrap for improved tissue imaging

Tue, 22 Aug 2017 02:00:00 +0200

Researchers at Tokai University describe in Advanced Materials how wrapping biological tissue in a nanosheet of a particular organic material results in high-quality microscopy images.  Application of the wrap prevents the sample from drying out, and hence from shrinking, enabling larger image-recor...

Crowdfunding triggers Capital Increase of 800,000 Euros at Rodos Biotarget

Tue, 22 Aug 2017 02:00:00 +0200

Rodos Biotarget is the first German life-science company to initiate crowdfunding campaigns via two crowd platforms. In 2016, a first round took place with Seedmatch, and a current financing round is running with aescuvest. With this approach, in addition to raising capital for further corporate dev...


Tue, 22 Aug 2017 02:00:00 +0200

CHEMIE.DE Information Service GmbH, provider of market-leading B2B portals and newsletters covering chemistry, life science, lab equipment, pharma and analytics, is now operating under the new name of LUMITOS®. The motive for the name change is a significant enhancement of the company’s business mod...

A new method for the 3-D printing of living tissues

Mon, 21 Aug 2017 10:09:45 +0200

Scientists at the University of Oxford have developed a new method to 3D-print laboratory-grown cells to form living structures. The approach could revolutionise regenerative medicine, enabling the production of complex tissues and cartilage that would potentially support, repair or augment diseased...

Hemorrhagic Fevers: Countering Inflammation to Prevent Circulatory Failure

Mon, 21 Aug 2017 07:00:10 +0200

Hemorrhagic fevers are severe viral diseases that are often fatal. Researchers from the University of Basel have now identified messenger substances of the immune system, which in infected mice lead to the development of shock. These results open up new possibilities for the development of life-savi...

Are stem cells the link between bacteria and cancer?

Mon, 21 Aug 2017 07:00:08 +0200

Gastric carcinoma is one of the most common causes of cancer-related deaths, primarily because most patients present at an advanced stage of the disease. The main cause of this cancer is the bacterium Helicobacter pylori, which chronically infects around half of all humans. However, unlike tumour vi...

Using barcodes to trace cell development

Fri, 18 Aug 2017 11:29:55 +0200

There are various concepts about how blood cells develop. However, they are based almost exclusively on experiments that solely reflect snapshots. Scientists from the German Cancer Research Center in Heidelberg now present a novel technique that captures the process in a dynamic way. Using a "random...

Curetis Announces Management Board Changes

Fri, 18 Aug 2017 07:00:11 +0200

Curetis N.V. announced several changes in its Management Board. Andreas Boos, CTO and co-founder of Curetis, is stepping down from the Management Board of Curetis N.V. to focus on his role as the group´s CTO and program director for the Gyronimo platform development. Andreas will continue to serve a...

Immunotherapy treatment shows effectiveness against deadly brain tumor during early tests

Fri, 18 Aug 2017 07:00:07 +0200

Glioblastoma is an aggressive, stubborn brain tumor with low odds of survival for patients. Now, University of Florida Health researchers have found a way to target a molecule that lets the tumor grow, migrate and evade the body’s immune system. The molecule, known as CD70, is found on the surface o...

Chewing gum rapid test for inflammation

Thu, 17 Aug 2017 11:02:06 +0200

Dental implants occasionally entail complications: Six to fifteen percent of patients develop an inflammatory response in the years after receiving a dental implant. This is caused by bacteria destroying the soft tissue and the bone around the implant in the worst case. In future, patients will bene...

How protein islands form

Thu, 17 Aug 2017 07:00:06 +0200

The immune system protects humans from threats such as, for example, disease-causing bacteria, and cancer as well. Yet if the system malfunctions, it can attack the body it is supposed to defend and cause autoimmune diseases such as type one diabetes mellitus or multiple sclerosis. The working group...

Gold shines through properties of nano biosensors

Thu, 17 Aug 2017 07:00:02 +0200

With their remarkable electrical and optical properties, along with biocompatibility, photostability and chemical stability, gold nanoclusters are gaining a foothold in a number of research areas, particularly in biosensing and biolabeling. These gold nanoclusters are chemically protected by ligands...

Circular RNA linked to brain function

Wed, 16 Aug 2017 11:16:38 +0200

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders. While hundreds of...

RNA: a vicious pathway to cancer?

Wed, 16 Aug 2017 07:00:02 +0200

According to the current doctrine, cancer cells develop due to mutations in genomic DNA. But could it be also caused also by faulty RNA molecules? A number of clues are pointing to this surprising hypothesis. Rolf Marschalek from the Institute of Pharmaceutical Biology at Goethe University Frankfurt...

Cancer detection with sugar molecules

Tue, 15 Aug 2017 11:05:52 +0200

Scientists from the University of Würzburg have synthesized a complex sugar molecule which specifically binds to the tumor protein Galectin-1. This could help to recognize tumors at an early stage and to combat them in a targeted manner. Galectins are a family of proteins that have become a promisi...

Many proteins must set to work so as to activate fat

Tue, 15 Aug 2017 07:00:07 +0200

What happens and where, when the body’s fat stores are activated? With the support of the Austrian Science Fund FWF, the biochemist Ruth Birner-Grünberger investigates the complex interaction of activation and regulation in fat breakdown, thus providing a basis for new therapeutic approaches for ill...

Drug Approval: New Country Comparison Shows Great Savings Potential

Tue, 15 Aug 2017 07:00:05 +0200

The regulatory requirements for the approval of new drugs vary greatly internationally in regards to the resources allocated to the authorities, the evaluation periods for approval and the fees for the pharmaceutical companies. This reports a study of the European Center of Pharmaceutical Medicine a...

Eppendorf grows faster than the market

Mon, 14 Aug 2017 07:00:08 +0200

During the first half of 2017, the Eppendorf Group achieved group sales of €327.9 million (prior-year period: €305.5 million). At 7.3% (6.6% when adjusted for currency effects), growth in sales lay above average market growth in the life science industry. Income from operations (EBIT) climbed 9.1% t...

analytica China 2018: Bigger and new layout

Mon, 14 Aug 2017 07:00:06 +0200

Asia’s leading trade show for analysis, lab technology and biotechnology, analytica China, will open again at Hall E1 to E4, Shanghai New International Expo Center from October 31 to November 2, 2018. The exhibition is a spin-off of analytica in Germany—the leading international fair for laboratory ...

Cellular transport routes

Mon, 14 Aug 2017 07:00:02 +0200

Unlike many other organisms, plants can’t simply run away from environmental conditions that change for the worse. Nonetheless, plants have the ability to react to environmental effects. These reactions are initially subtle: they occur within their individual cells. Plants move proteins inside these...

Multi-nutrient rice against malnutrition

Fri, 11 Aug 2017 11:08:29 +0200

ETH researchers have developed a new rice variety that not only has increased levels of the micronutrients iron and zinc in the grains, but also produces beta-carotene as a precursor of vitamin A. This could help to reduce micronutrient malnutrition, or «hidden hunger», which is widespread in develo...

Researchers discover new genetic mutation that causes male infertility

Fri, 11 Aug 2017 07:00:12 +0200

Researchers at Ben-Gurion University of the Negev and Soroka University Medical Center in Beer-Sheva, Israel have discovered a new genetic mutation that prevents sperm production. Five percent of men suffer from infertility and approximately one percent suffer from azoospermia, which is a condition ...

How food preservatives may disrupt human hormones and promote obesity

Fri, 11 Aug 2017 07:00:03 +0200

Can chemicals that are added to breakfast cereals and other everyday products make you obese? Growing evidence from animal experiments suggests the answer may be "yes." But confirming these findings in humans has faced formidable obstacles - until now. A new study published in Nature Communications ...

Spider peptides battle superbugs and cancer

Fri, 11 Aug 2017 07:00:01 +0200

As antibiotic resistance rises and fears over superbugs grow, scientists are looking for new treatment options. One area of focus is antimicrobial peptides (AMPs), which could someday be an alternative to currently prescribed antibiotics, many of which are becoming increasingly useless against some ...

High resolution without particle accelerator

Thu, 10 Aug 2017 11:04:22 +0200

A visit to the optometrist often involves optical coherence tomography. This imaging process uses infrared radiation to penetrate the layers of the retina and examine it more closely in three dimensions, without having to touch the eye at all. This allows eye specialists to diagnose diseases such as...

New therapy to combat skin cancer

Thu, 10 Aug 2017 09:37:49 +0200

In the field of dermatology, Zimmer MedizinSysteme GmbH, a company based in Neu-Ulm (southern Germany), has long been the global market leader for cryotherapy products. In founding the spin-off Zimmer BioTech, the company is now taking another step forward and utilising its wealth of experience to t...

Medication for the unborn baby

Thu, 10 Aug 2017 07:00:06 +0200

An Empa team has succeeded in developing a new three-dimensional cell model of the human placental barrier. The "model organ" can quickly and reliably deliver new information on the intake of substances, such as nano-particles, by the placental barrier and on any possible toxic effects for the unbor...

Merck and Baylor College of Medicine Advance Vaccine Development and Manufacturing for Neglected Diseases

Thu, 10 Aug 2017 07:00:03 +0200

Merck announced that it has formed a strategic alliance with Baylor College of Medicine (Texas, U.S.) and its vaccine product development partnership (PDP), Texas Children’s Hospital Center for Vaccine Development (Texas Children’s CVD), to advance vaccine research and development for neglected and ...

New anti-malarial lead compound successfully tested

Wed, 09 Aug 2017 11:08:34 +0200

Researchers in a team headed by Professor Thomas Kurz at the Institute of Pharmaceutical and Medicinal Chemistry of Heinrich Heine University Düsseldorf (HHU) have successfully tested an optimised lead compound in animal experiments that acts against plasmodia, i.e. malaria parasites. Lead compounds...

Medigene announces formation of new Scientific Advisory Board

Wed, 09 Aug 2017 07:00:08 +0200

Medigene AG announced the appointment of eight leading experts to its new immuno-oncology-focused Scientific Advisory Board (SAB). The SAB will consult the company with regard to strategic options and future perspectives within its research and development activities. The SAB will thereby further st...

Common, edible mushroom has potential to kill one type of leukemia cell

Wed, 09 Aug 2017 07:00:07 +0200

An edible, shaggy-looking mushroom contains a protein that is a potent killer of a certain leukemia cell, a group of University of Florida researchers has found. The Coprinus comatus mushroom, commonly known as the lawyer’s wig or shaggy mane, killed human T-cell leukemia cells during laboratory tes...

New biomarker found for group of rare metabolic diseases

Wed, 09 Aug 2017 07:00:05 +0200

A newly discovered biomarker associated with a rare metabolic disorder may facilitate better diagnosis and identification of new drugs for clinical trials for the disease, according to researchers in the Perelman School of Medicine at the University of Pennsylvania. Development of treatments for the...

"Origami organs" can potentially regenerate tissues

Tue, 08 Aug 2017 14:00:01 +0200

Northwestern Medicine scientists and engineers have invented a range of bioactive "tissue papers" made of materials derived from organs that are thin and flexible enough to even fold into an origami bird. The new biomaterials can potentially be used to support natural hormone production in young can...

New, more sensitive sensor for evaluating drug safety

Tue, 08 Aug 2017 11:29:22 +0200

A new technique for evaluating drug safety can detect stress on cells at earlier stages than conventional methods, which mostly rely on detecting cell death. The new method uses a fluorescent sensor that is turned on in a cell when misfolded proteins begin to aggregate -- an early sign of cellular s...

Microbot origami can capture, transport single cells

Tue, 08 Aug 2017 07:00:09 +0200

Researchers at North Carolina State University and Duke University have developed a way to assemble and pre-program tiny structures made from microscopic cubes - "microbot origami" - to change their shape when actuated by a magnetic field and then, using the magnetic energy from their environment, p...

Financial decisions influenced by intensity of light

Tue, 08 Aug 2017 07:00:08 +0200

A study of more than 2,500 people provides new evidence about the effects of luminance on the quality and consistency of our financial decision-making. Luminance is a measurement of the amount of light that falls on the earth's surface, which can be affected by cloud cover, humidity, suspended parti...

Multiple roles of glucose metabolism in platelet activation and survival identified

Mon, 07 Aug 2017 14:00:02 +0200

Platelets, the cells in blood that enable clotting, are highly reliant on their ability to metabolize glucose, according to a new study by researchers at the University of Iowa. The findings may have implications for understanding the increased risk of thrombosis--blood clots inside blood vessels--i...

Drug short-circuits cancer signaling

Mon, 07 Aug 2017 14:00:00 +0200

Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have published a study shedding new light on how K-80003 (TX803), an anti-cancer agent discovered at the Institute, prevents activation of the PI3K pathway, resulting in inhibition of cancer cell growth. Because the PI3K pathway...

Immune cells may be key to better allergy, infection therapies

Mon, 07 Aug 2017 11:26:17 +0200

By learning how a recently discovered immune cell works in the body, researchers hope to one day harness the cells to better treat allergies and infections, according to new Cornell University research. Type 1 regulatory (Tr1) cells are a type of regulatory immune cell that help suppress immune resp...

Researchers discover Achilles' heel of bacteria

Mon, 07 Aug 2017 11:17:27 +0200

Salmonellae are particularly resistant to antibiotics since they possess not only one, but two membranes that protect them from harmful substances. This makes them members of the so-called Gram-negative bacteria. Since Salmonella infections are becoming increasingly difficult to treat with antibioti...

Unknown virus in ‘throwaway’ DNA discovered

Mon, 07 Aug 2017 10:58:27 +0200

In research scientists from Oxford University’s Department of Zoology have revealed that Next-Generation Sequencing and its associated online DNA databases could be used in the field of viral discovery. They have developed algorithms that detect DNA from viruses that happen to be in the blood or tis...

Lonza Acquires Micro-Macinazione

Mon, 07 Aug 2017 07:00:07 +0200

Lonza has acquired Micro-Macinazione, providing micronization of active ingredients for the pharmaceutical and fine chemical industries. Micro-Macinazione, which had sales of ~ CHF 20 million in 2016, has 120 employees and is based in Monteggio, Switzerland. Micro-Macinazione was purchased from Cros...

More functional DNA in mitochondria cures male infertility

Mon, 07 Aug 2017 07:00:01 +0200

Male infertility can be caused by mutations in the DNA of mitochondria, the powerhouses of cells. By increasing the total DNA amount in mitochondria, scientists from the Max Planck Institute for Biology of Ageing in Cologne restored testis function and semen quality in infertile mice. Worldwide app...

EPA to Grant Merck’s Patent Application for CRISPR Technology

Fri, 04 Aug 2017 14:00:01 +0200

Merck announced the European Patent Office (EPO) has issued a “Notice of Intention to Grant” for Merck’s patent application covering the company’s CRISPR technology used in a genomic integration method for eukaryotic cells. The patent will provide Merck’s CRISPR genomic integration technology with b...

Executive Board Changes at Merck

Fri, 04 Aug 2017 07:00:12 +0200

The Personnel Committee of E. Merck KG has decided on changes in the responsibilities of the Executive Board of Merck KGaA, Darmstadt, effective September 1, 2017. Walter Galinat (61) will hand over responsibility for the Performance Materials business of Merck to his Executive Board colleague Kai B...

Imaging tracer allows early assessment of abdominal aortic aneurysm risk

Fri, 04 Aug 2017 07:00:10 +0200

Yale University researchers have developed a way in which medical imaging could potentially be used to assess a patient's rupture risk for abdominal aortic aneurysm. Delaying surgical treatment can be life-threatening, and this new type of imaging could allow physicians to diagnose disease and bette...

Merck Sets Course for Future Growth

Fri, 04 Aug 2017 07:00:08 +0200

Merck reported an increase in sales in the second quarter of 2017 along with a decline in EBITDA pre exceptionals compared with the year-earlier period. Merck confirmed its earnings guidance following the first six months of 2017. “We have set the course for future growth. By focusing on innovative ...

Safely releasing genetically modified genes into the wild

Thu, 03 Aug 2017 14:00:06 +0200

So, you've genetically engineered a malaria-resistant mosquito, now what? How many mosquitos would you need to replace the disease-carrying wild type? What is the most effective distribution pattern? How could you stop a premature release of the engineered mosquitos? Releasing genetically engineered...