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Molecule flash mob

Fri, 20 Jan 2017 13:00:05 +0100

Neurotransmitter transporters are some of the most popular transport proteins in research as they play a major role in the processing of signals in the brain. A joint study by TU Wien and the Medical University of Vienna has now successfully demonstrated for the first time the structural impact of m...

Gyros Protein Technologies appoints Gerrit van den Dool to Board of Directors

Fri, 20 Jan 2017 13:00:04 +0100

Gyros Protein Technologies AB, a pioneer in automated nanoliter-scale immunoassays and leading provider of peptide synthesizers and reagents, announced today the appointment of Gerrit van den Dool to its Board of Directors, as a Non-Executive Director. With more than 25 years’ experience in the life...

Sosei appoints Andrew Oakley as CFO

Fri, 20 Jan 2017 13:00:04 +0100

Sosei Group Corporation announces the appointment of Andrew Oakley as Chief Financial Officer (CFO) effective from February 1 2017. Mr Oakley will be based in Sosei’s Tokyo offices. Mr Oakley will succeed Mr Hidetoshi Torami who has resigned from Sosei for personal reasons. Mr Oakley, a Chartered Ac...

Avillion appoints Mark Weinberg as Chief Medical Officer

Fri, 20 Jan 2017 13:00:03 +0100

Avillion LLP, a co-developer and financier of late-stage pharmaceutical product candidates, announces the appointment of Mark Weinberg, MD MBA as Chief Medical Officer. Dr Weinberg will be based in Chicago, USA. Dr Weinberg has spent more than 17 years as a pharmaceutical and biotech executive with ...

WALDNER Laboreinrichtungen extends Management Board

Fri, 20 Jan 2017 11:42:20 +0100

Joerg Hoffmann has been appointed to the management board of WALDNER Laboreinrichtungen GmbH & Co. KG just over 100 days ago. Together with Horst Schierholz he is responsible for the corporation and will provide new impetus regarding international sales. “We have to position ourselves in an even mo...

Agilent Technologies extends collaboration on reproductive genetics

Fri, 20 Jan 2017 06:00:07 +0100

Agilent Technologies announced that it is extending its collaboration with the Centre for Human Genetics of the University of Leuven and the University Hospital of Leuven in Belgium. Joris Vermeesch, chair of the Centre for Human Genetics and a leading expert in human genetics, will coordinate the c...

Blood-repellent materials: A new approach to medical implants

Fri, 20 Jan 2017 06:00:05 +0100

Medical implants like stents, catheters and tubing introduce risk for blood clotting and infection - a perpetual problem for many patients. Colorado State University engineers offer a potential solution: A specially grown, "superhemophobic" titanium surface that's extremely repellent to blood. The m...

Toward a 'smart' patch that automatically delivers insulin when needed

Fri, 20 Jan 2017 06:00:03 +0100

Treatment for certain diabetes cases involves constant monitoring of blood-glucose levels and daily insulin shots. But scientists are now developing a painless "smart" patch that monitors blood glucose and releases insulin when levels climb too high. The device has been tested on mice. People with T...

Siemens and Biogen cooperate

Thu, 19 Jan 2017 13:21:22 +0100

Siemens Healthineers and Biogen announced that the companies plan to jointly develop magnetic resonance imaging (MRI) applications with the intent of quantifying key markers of multiple sclerosis (MS) disease activity and progression. Siemens Healthineers aims to enable healthcare providers to meet ...

Evotec enters into an integrated drug discovery collaboration with Asahi Kasei Pharma

Thu, 19 Jan 2017 13:00:08 +0100

Evotec AG announced it has entered into an integrated drug discovery collaboration on an ion channel target with Asahi Kasei Pharma Corporation, a wholly owned subsidiary of Asahi Kasei Corporation, Tokyo, Japan. Under the terms of the agreement, Evotec will apply its integrated drug discovery platf...

OCTIMET secures over EUR 11 million to develop its highly selective MET kinase inhibitors

Thu, 19 Jan 2017 13:00:02 +0100

OCTIMET Oncology NV, has secured EUR 11.3 million in a Series A investment round, enabling the company to accelerate the development of a clinically de-risked MET kinase inhibitor, as single agent or in combination with standard of care and targeted agents for the treatment of solid cancers. OCTIMET...

Merck opens production facility exclusively for meglumine in Spain

Thu, 19 Jan 2017 06:00:19 +0100

Merck announced the opening of a facility in Mollet des Vallès, Spain dedicated to the manufacture of meglumine, an FDA-approved excipient for pharmaceuticals and a component of medical imaging contrast media.The facility, validated by the FDA, is the only location in Europe that manufactures meglum...

Researchers zero-in on cholesterol's role in cells

Thu, 19 Jan 2017 06:00:07 +0100

Scientists have long puzzled over cholesterol. It's biologically necessary; it's observably harmful - and nobody knows what it's doing where it's most abundant in cells: in the cell membrane. Now, for the first time, chemists at the University of Illinois at Chicago have used a path-breaking optical...

World's first total-body PET scanner takes a big step forward

Thu, 19 Jan 2017 06:00:06 +0100

The UC Davis-based EXPLORER consortium, which aims to build a revolutionary total-body PET (positron emission tomography) scanner, has announced the selection of two industry partners to help build the prototype device. They are United Imaging Healthcare America, a North American subsidiary of Shang...

'5-D protein fingerprinting' could give insights into Alzheimer's, Parkinson's

Thu, 19 Jan 2017 06:00:05 +0100

In research that could one day lead to advances against neurodegenerative diseases like Alzheimer's and Parkinson's, University of Michigan engineering researchers have demonstrated a technique for precisely measuring the properties of individual protein molecules floating in a liquid. Proteins are ...

The computer as microscope

Wed, 18 Jan 2017 10:12:51 +0100

Protein switches are active everywhere in the body and often affect the generation of diseases. Thanks to a special method, researchers from Bochum have gained new insights into their workings. Using a combination of infrared spectroscopy and computer simulation, researchers at Ruhr-Universität Boch...

Every Meal Triggers Inflammation

Wed, 18 Jan 2017 06:00:07 +0100

When we eat, we do not just take in nutrients – we also consume a significant quantity of bacteria. The body is faced with the challenge of simultaneously distributing the ingested glucose and fighting these bacteria. This triggers an inflammatory response that activates the immune systems of health...

WILEX signs antibody license agreement with Telix Pharmaceuticals Limited

Wed, 18 Jan 2017 06:00:04 +0100

WILEX AG and Australian biopharmaceutical company Telix Pharmaceuticals Limited, announced that they have concluded a worldwide license agreement for the development and commercialization of the imaging agent REDECTANE®, a radiolabeled form of the monoclonal antibody Girentuximab. Girentuximab binds...

Nanoparticle Exposure Can Awaken Dormant Viruses

Wed, 18 Jan 2017 01:00:00 +0100

Nanoparticles from combustion engines can activate viruses that are dormant in in lung tissue cells. This is the result of a study by researchers of Helmholtz Zentrum München, a partner in the German Center for Lung Research (DZL). To evade the immune system, some viruses hide in cells of their hos...

Evotec and MaRS Innovation establish strategic partnership

Tue, 17 Jan 2017 13:00:01 +0100

Evotec AG and MaRS Innovation announced the launch of Fibrocor Therapeutics LP, a Toronto-based company focused on developing first-in-class therapeutics targeting fibrotic diseases. The company was launched with CDN $ 2.8 m (approx. $ 2.1 m) financing, which includes cash from MaRS Innovation. Evot...

With scissors and string  

Tue, 17 Jan 2017 08:58:18 +0100

Once together, never apart – isn’t that how the saying goes? Not so in meiosis, the special type of cell division in which gametes, sperm and egg cells are formed. At the start of meiosis the ring-shaped protein complex, referred to as cohesin, is the string that ties the chromosome strands together...

What makes erionite carcinogenic?

Tue, 17 Jan 2017 06:00:08 +0100

The mineral erionite is considered to be highly carcinogenic and is on the World Health Organisation’s list of substances that cause cancer. A few years ago, an entire village in Turkey actually had to be moved, because the substance was very common in the surrounding area and every second inhabitan...

High levels of hospital-acquired infection on children's intensive care wards

Tue, 17 Jan 2017 06:00:06 +0100

The report, published in The Lancet Infectious Diseases, found that one in six children in paediatric intensive care units, and one in ten babies in neonatal intensive care units had developed hospital infections while being treated. The study found that the pattern of hospital-acquired infections i...

Biofuel matchmaker: Finding the perfect algae for renewable energy

Tue, 17 Jan 2017 06:00:05 +0100

A dozen glass cylinders containing a potential payload of bright green algae are exposed to hundreds of multi-colored lights, which provide all of sunlight's natural hues. The tiny LEDs brighten and dim to mimic the outdoors' constantly changing conditions. To further simulate a virtual cloud passin...

Grünenthal introduces Latin America’s most modern Women’s Health Products plant

Mon, 16 Jan 2017 13:00:01 +0100

Grünenthal announced the introduction of its new women’s health products plant today. Grünenthal invested USD 14.5 million to build the 1,150 m 2 hormone plant, which is the company’s center of excellence for hormone production and the most modern in Latin America. The new facility will initially de...

'Mysterious' non-protein-coding RNAs play important roles in gene expression

Mon, 16 Jan 2017 10:06:27 +0100

In cells, DNA is transcribed into RNAs that provide the molecular recipe for cells to make proteins. Most of the genome is transcribed into RNA, but only a small proportion of RNAs are actually from the protein-coding regions of the genome. "Why are the non-coding regions transcribed at all? Their f...

How well do we understand the relation between incorrect chromosome number & cancer?

Mon, 16 Jan 2017 06:00:06 +0100

Over a century ago, a German-born scientist experimenting with impregnated sea urchin eggs had an insight that led to one of the first modern theories of cancer. Theodor Boveri linked incorrect chromosome number in urchin embryos with abnormal development. In 1902 he reasoned that having the wrong n...

Merck Drives Business Opportunities in the U.S.

Mon, 16 Jan 2017 06:00:04 +0100

Merck announced two collaborations in the metropolitan area of San Francisco, California (USA). The company is now cooperating with Palantir Technologies Inc., Palo Alto, California, and with the Stanford Graduate School of Business (Stanford GSB), Stanford, California. In addition, Merck signed thr...

Crybaby: The vitamins in your tears

Fri, 13 Jan 2017 13:00:03 +0100

Babies cry easily, but those tears may help shed light on the role and potential uses of vitamins in tears. Maryam Khaksari, a research specialist at the Chemical Advanced Resolution Methods (ChARM) Laboratory at Michigan Tech, is the lead author of a paper on the subject. "Our goal was to seek the ...

Study outlines framework for identifying disease risk in genome sequence

Fri, 13 Jan 2017 13:00:02 +0100

Imagine a day when you visit the doctor's office for your annual physical. Your physician orders routine tests - cholesterol, glucose and blood count - but they also order a sequence of your genome, all 3 billion letters of it. Routine genomic testing is not far away, according to researchers at The...

Scientists reveal non-addictive pathway to pain relief

Fri, 13 Jan 2017 13:00:01 +0100

OHSU research suggests an avenue for developing treatments for chronic pain that harness the medicinal properties of cannabis while minimizing the threat of addiction. The study , conducted in a rodent model, provides additional rationale for the development of therapeutics using cannabinoid recepto...

Bacterial protein structure could aid development of new antibiotics

Fri, 13 Jan 2017 10:16:00 +0100

Bacterial cells have an added layer of protection, called the cell wall, that animal cells don't. Assembling this tough armor entails multiple steps, some of which are targeted by antibiotics like penicillin and vancomycin. Yet one step in the process has remained a mystery because the molecular str...

Manipulating signals in bacteria could reduce illnesses

Fri, 13 Jan 2017 06:00:13 +0100

The University of Illinois at Chicago College of Pharmacy has received a five-year, $1.25 million federal grant to continue its research into how bacteria that cause streptococcal infections can be manipulated. By studying the chemical signals of bacteria, Michael Federle, associate professor of med...

Stem cells used to regenerate the external layer of a human heart

Fri, 13 Jan 2017 06:00:12 +0100

A process using human stem cells can generate the cells that cover the external surface of a human heart -- epicardium cells -- according to a multidisciplinary team of researchers. "In 2012, we discovered that if we treated human stem cells with chemicals that sequentially activate and inhibit Wnt ...

Catching CRISPR in action

Fri, 13 Jan 2017 06:00:06 +0100

One of the most talked about biological breakthroughs in the past decade was the discovery of the genome editing tool CRISPR/Cas9, which can alter DNA and potentially remove the root causes of many hereditary diseases. Originally found as part of the immune system of the Streptococcus pyogenes bacte...

Merck Licenses Four Oncology Research and Development Programs from Vertex

Thu, 12 Jan 2017 13:00:06 +0100

Merck announced that it has entered into a licensing agreement with Vertex Pharmaceuticals Inc. for the worldwide development and commercialization of four promising research and development programs that represent novel approaches to the treatment of cancer.“With this strategic deal we significantl...

Using nature's weaving formula to engineer advanced functional materials

Thu, 12 Jan 2017 13:00:03 +0100

For the first time, UNSW biomedical engineers have woven a 'smart' fabric that mimics the sophisticated and complex properties of one nature's ingenious materials, the bone tissue periosteum. Having achieved proof of concept, the researchers are now ready to produce fabric prototypes for a range of ...

Tecan appoints Klaus Lun Head of the Life Sciences Business division

Thu, 12 Jan 2017 06:00:17 +0100

The Tecan Group announced that Dr. Klaus Lun, Head of Corporate Development and a member of the Management Board of the Tecan Group since June 2013, has been appointed Head of the Life Sciences Business division. On December 14, 2016, Tecan announced that Dr. Stefan Traeger, Head of the Life Science...

A glimpse into the workings of the baby brain

Thu, 12 Jan 2017 06:00:15 +0100

In adults, certain regions of the brain’s visual cortex respond preferentially to specific types of input, such as faces or objects — but how and when those preferences arise has long puzzled neuroscientists. One way to help answer that question is to study the brains of very young infants and compa...

Pharmaron Acquires Xceleron Inc.

Thu, 12 Jan 2017 06:00:13 +0100

Pharmaron, a fully integrated contract research organization offering R&D services for the life science industry, today announced the acquisition of Xceleron Inc. Xceleron is a Maryland, US-based globally leading Accelerator Mass Spectrometry (AMS) specialist for life sciences. The AMS platform deve...

LabCorp to acquire assets of Mount Sinai Health System Clinical Outreach Laboratories

Thu, 12 Jan 2017 06:00:13 +0100

Laboratory Corporation of America ® Holdings and the Mount Sinai Health System have entered into a definitive agreement for LabCorp to acquire assets of Mount Sinai’s Clinical Outreach Laboratories. When the transaction is complete, LabCorp will be available to provide comprehensive laboratory servi...

New subtype of cervical cancer discovered

Thu, 12 Jan 2017 06:00:05 +0100

A team of University of South Carolina scientists led by Carolyn Banister and Phillip Buckhaults has identified a new subtype of cervical cancer that, like most cervical cancers, is triggered by human papillomavirus (HPV) but whose growth is not directed by the virus, suggesting that therapy targeti...

The strange double life of Dab2

Wed, 11 Jan 2017 06:00:12 +0100

Sometimes proteins do a lot more than we expect. Dab2, for example, has long been linked to cancer. The molecule is associated with a chain of signaling proteins called the Ras-MAPK pathway. In many cancers, elements of Ras-MAPK mutate and start telling cells to grow uncontrollably. Sylvester Compre...

For chemicals, mega is out and bio is in

Wed, 11 Jan 2017 06:00:09 +0100

Ramon Gonzalez sees flares burning methane from the stacks above Houston’s refineries and thinks, “What a waste.” He believes that methane represents an opportunity for biomanufacturing that should not be missed. The Rice University professor and director of its new Advanced Biomanufacturing Initiat...

QIAGEN enhances bioinformatics portfolio with acquisition of OmicSoft

Wed, 11 Jan 2017 06:00:04 +0100

QIAGEN announced the acquisition of OmicSoft Corporation, providing access to OmicSoft’s powerful multi-omics data management infrastructure solution as well as expertly curated ‘omics’ data sets that complement QIAGEN’s bioinformatics portfolio that are relied upon by customers worldwide to gain va...

New insights into mechanisms of breast cancer development and resistance to therapy

Wed, 11 Jan 2017 06:00:01 +0100

Why does breast cancer develop and how come certain patients are resistant to established therapies? Researchers from the University of Basel have gained new insights into the molecular processes in breast tissue. They identified the tumor suppressor LATS as a key player in the development and treat...

Merck and MD Anderson Cancer Center Enter Three-Year Strategic Collaboration

Tue, 10 Jan 2017 13:00:04 +0100

Merck and The University of Texas MD Anderson Cancer Center announced a three-year strategic collaboration, with the aim of more quickly advancing the development of investigational cancer therapies in four cancers – breast, colorectal, glioblastoma and leukemia. “This collaboration illustrates our ...

Aggressive prostate cancer secrets revealed

Tue, 10 Jan 2017 13:00:03 +0100

A landmark study, led by Monash University's Biomedicine Discovery Institute with the involvement of the Peter MacCallum Cancer Centre, has revealed the reason why men with a family history of prostate cancer who also carry the BRCA2 gene fault have a more aggressive form of prostate cancer. The stu...

Transfusions of 'old' blood may harm some patients

Tue, 10 Jan 2017 13:00:01 +0100

The oldest blood available for transfusions releases large and potentially harmful amounts of iron into patients' bloodstreams, a new study by researchers at Columbia University Medical Center (CUMC) has found. Based on the new findings, the researchers recommend that the FDA reduce the maximum stor...

Progesterone may be key to preventing recurrent miscarriage

Tue, 10 Jan 2017 13:00:00 +0100

For women who suffer multiple pregnancy losses in the first four to six weeks of gestation, the hormone progesterone could offer hope for a successful birth, according to a new study by Yale School of Medicine researchers and their colleagues at University of Illinois at Chicago. Fetal death, or int...