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Cancer diagnosis with a breath test

Fri, 21 Apr 2017 11:12:43 +0200

“Inhale deeply ... and exhale.” This is what a test for lung cancer could be like in future. Scientists at the Max Planck Institute for Heart and Lung Research in Bad Nauheim have developed a method that can detect the disease at an early stage. To this effect, they investigated the presence of trac...

Gut bacteria affect ageing

Fri, 21 Apr 2017 11:12:41 +0200

It loses its pigments, its motor skills and mental faculties decline, it gets cancer – the turquoise killifish (Nothobranchius furzeri) struggles with the same signs of old age that affect many other living creatures. Researchers at the Max Planck Institute for Biology of Ageing in Cologne have stud...

Fungi have enormous potential for new antibiotics

Fri, 21 Apr 2017 07:00:12 +0200

Fungi are a potential goldmine for the production of pharmaceuticals. This is shown by researchers at Chalmers University of Technology, who have developed a method for finding new antibiotics from nature’s own resources. The findings – which could prove very useful in the battle against antibiotic ...

Strawberries against breast cancer?

Fri, 21 Apr 2017 07:00:04 +0200

A study by European and Latin American researchers has shown that strawberry extract can inhibit the spread of laboratory-grown breast cancer cells, even when they are inoculated in female mice to induce tumours. However, the scientists do point out that these results from animal testing can not be ...

Frog slime kills flu virus

Fri, 21 Apr 2017 07:00:03 +0200

A component of the skin mucus secreted by South Indian frogs can kill the H1 variety of influenza viruses, researchers from Emory Vaccine Center and the Rajiv Gandhi Center for Biotechnology in India have discovered. Frogs' skins were known to secrete "host defense peptides" that defend them against...

Synthetic Carbohydrates against Autoimmune Diseases

Thu, 20 Apr 2017 07:00:08 +0200

Researchers are developing an innovative approach for the treatment of a rare autoimmune disease of the peripheral nervous system, using a type of molecular sponge consisting of carbohydrates to remove pathogenic antibodies from the bloodstream. Developed to treat anti-MAG neuropathy, the approach a...

Stress can increase empathy

Thu, 20 Apr 2017 07:00:07 +0200

Acute psychosocial stress leads to increased empathy and prosocial behavior. An international team of researchers led by Claus Lamm from the University of Vienna investigated the effects of stress on neural mechanisms and tested the relationship between empathy and prosocial behavior in a new experi...

Chaining up diarrhoea pathogens

Thu, 20 Apr 2017 07:00:04 +0200

Researchers have clarified how vaccinations can combat bacterial intestinal diseases: vaccine-induced antibodies in the intestine chain up pathogens as they grow in the intestine, which prevents disease and surprisingly also hinders the spread of antibiotic resistance. Vaccinations are known to prot...

Gelatine instead of forearm

Thu, 20 Apr 2017 07:00:03 +0200

The characteristics of human skin are heavily dependent on the hydration of the tissue - in simple terms, the water content. This also changes its interaction with textiles. Up to now, it has only been possible to determine the interaction between human skin and textiles by means of clinical trials ...

What makes pancreatic cancer so aggressive?

Thu, 20 Apr 2017 07:00:02 +0200

Pancreatic cancer is one of the most aggressive tumour types because it starts forming metastases early. The cancer itself, however, is usually only discovered late. This leads to a high patient mortality rate. Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have now discovere...

Drug pair slows progression of muscular dystrophy in animal models

Wed, 19 Apr 2017 14:00:01 +0200

A pair of protein-inhibiting compounds is effective at slowing the progression of a form of muscular dystrophy in animal models, a group of University of Florida Health researchers has found. The compounds of this novel drug class are particularly intriguing for use by Duchenne muscular dystrophy pa...

Merck Furthers Commitment Towards Elimination of Schistosomiasis

Wed, 19 Apr 2017 07:00:13 +0200

Merck announced it has formed a public-private partnership for the next three years with the Australian Institute of Tropical Health and Medicine (James Cook University, Queensland) and Baylor College of Medicine (Texas, USA) to strengthen the current work on diagnostic development in schistosomiasi...

Are tumor cells glutamine addicts?

Wed, 19 Apr 2017 07:00:12 +0200

Many tumors are thought to depend on glutamine, suggesting glutamine deprivation as therapeutic approach, but a new study shows that this effect might have been overestimated. Most cancers require large amounts of glutamine for rapid growth and there are numerous studies indicating that they cannot ...

Brain tissue from a petri dish

Wed, 19 Apr 2017 07:00:07 +0200

The most complex organ in humans is the brain. Due to its complexity and, of course, for ethical reasons, it is extremely difficult to do scientific experiments on it – ones that could help us to understand neurodegenerative diseases like Parkinson’s, for example. Scientists at the Luxembourg Centre...

High-salt diet decreases thirst, increases hunger

Wed, 19 Apr 2017 07:00:01 +0200

When you eat salty food, you get thirsty and drink water. Right? Maybe in the short-term, but within 24 hours, you actually get less thirsty because your body starts to conserve and produce more water. This counterintuitive discovery by scientists at Vanderbilt University and in Germany has upended ...

Due to an equipment failure the availability of albumin is currently limited

Tue, 18 Apr 2017 12:41:44 +0200

Biotest has started to inform its customers about an expected albumin supply shortage within the coming months. This is due to an equipment failure in the production of an albumin intermediate. The equipment failure has already been fixed. In accordance with the relevant authorities, Biotest decided...

LDC and SOTIO Enter License and Collaboration Agreement for First-in-class Cancer Metabolism Program

Tue, 18 Apr 2017 02:00:00 +0200

The Lead Discovery Center GmbH (LDC), Max Planck Innovation GmbH (MI) and SOTIO a.s. have signed a collaboration and license agreement providing SOTIO with exclusive rights to an oncology program addressing a novel target in tumor metabolism. It was discovered at the Max Planck Institute for Biology...

Autonomous sensor could aid in early detection of urinary tract infection

Tue, 18 Apr 2017 02:00:00 +0200

Urinary tract infections could one day be diagnosed faster than ever before with an autonomous sensor technology being developed at Purdue University. “Current testing relies on time-consuming and costly urine culture tests performed at medical facilities and on at-home testing using store-purchased...

Melatonin may protect the small intestine from oral radiation treatment in rats

Tue, 18 Apr 2017 02:00:00 +0200

Oral melatonin can protect the small intestine in rats subjected to radiotherapy of the tongue, according to a study by Germaine Escames from Universidad de Granada, Spain, and colleagues. Gut toxicity -- a debilitating condition involving deep ulcerations -- can limit the doses of radiotherapy giv...

Targeting blood vessels to improve cancer immunotherapy

Tue, 18 Apr 2017 02:00:00 +0200

EPFL scientists have improved the efficacy of cancer immunotherapy by blocking two proteins that regulate the growth of tumor blood vessels. Cancer immunotherapy aims to enhance or restore the ability of the patient's immune system - namely T cells - to recognize and attack cancer. But tumors use se...

Gene silencing shows promise for treating 2 fatal neurological disorders

Tue, 18 Apr 2017 02:00:00 +0200

In two studies of mice, researchers showed that a drug, engineered to combat the gene that causes spinocerebellar ataxia type 2 (SCA2), might also be used to treat amyotrophic lateral sclerosis (ALS). "Our results provide hope that we may one day be able to treat these devastating disorders," said S...

Algal residue - an alternative carbon resource for pharmaceuticals and polyesters

Tue, 18 Apr 2017 02:00:00 +0200

Microalgae have received much attention in biomass production due to many strains having a high biomass productivity per unit time and per unit area. Algae produce high levels of oil as well as carbohydrates, occurring mainly in the form of starch. They can survive in unfavorable, nutrient deficient...

From moo to goo

Thu, 13 Apr 2017 11:16:42 +0200

Oil and gas wells and even cattle release methane gas into the atmosphere, and researchers are working on ways to not only capture this gas but also convert it into something useful and less-polluting. Now scientists at the Department of Energy's Pacific Northwest National Laboratory have developed ...

Relocation of Proteins with a New Nanobody Tool

Thu, 13 Apr 2017 07:00:22 +0200

Researchers at the Biozentrum of the University of Basel have developed a new method by which proteins can be transported to a new location in a cell. The novel tool enables scientists to study the function of proteins depending on their position by using nanobodies. The tool can be used for a wide ...

Glowing bacteria detect buried landmines

Thu, 13 Apr 2017 07:00:03 +0200

The need for safe and efficient technologies for detecting buried landmines and unexploded ordnance is a humanitarian issue of immense global proportions. About half a million people around the world are suffering from mine-inflicted injuries, and each year an additional 15 to 20 thousand more peopl...

New method could deliver DNA-based vaccines in pill form

Thu, 13 Apr 2017 07:00:02 +0200

A microscopic corn-and-shrimp cocktail could eventually make DNA-based vaccinations and cancer-treating gene therapies an easier pill to swallow, according to new research from the University of Nebraska-Lincoln. In a recent study, the researchers demonstrated that nesting a specialized nanoparticle...

Enzymicals AG is a new 4chiral member

Thu, 13 Apr 2017 02:00:00 +0200

Enzymicals has been a member of the network 4chiral since 28.03.2017. With the slogan "Our core competence in organic synthesis", the network is conducting research and development projects in the field of organic synthesis. Enzymicals is now expanding the possibilities of the network by its experti...

SYGNIS AG successfully completes integration of recently acquired C.B.S. Scientific

Wed, 12 Apr 2017 14:00:03 +0200

SYGNIS AG announced the successful completion of the integration of C.B.S. Scientific Company Inc. (C.B.S.), a life sciences tools company located in San Diego, CA, USA. SYGNIS had announced the acquisition of C.B.S. in December 2016 and completed it in early January 2017. C.B.S. will be consolidate...

One step closer to crack the mystery of bacterial adaptation to antibiotics

Wed, 12 Apr 2017 11:17:51 +0200

An international team including researchers from MIPT's Laboratory for Advanced Studies of Membrane Proteins have proposed an explanation of the way bacteria process external signals. By identifying the detailed structure of the protein complex used by bacteria, the scientists gained insights into t...

Adding to theory about Huntington's mechanism

Wed, 12 Apr 2017 07:00:07 +0200

Rice University researchers are starting to understand how protein fragments influence the fiber aggregation suspected as a cause of Huntington's disease. In their computer simulations, Rice bioscientist Peter Wolynes and graduate student Mingchen Chen show that the N-terminal sequence in huntingtin...

Graphene and electricity to change stem cells for nerve regrowth

Wed, 12 Apr 2017 07:00:05 +0200

Schwann cells are an example. They form sheaths around axons, the tail-like parts of nerve cells that carry electrical impulses. They promote regeneration of those axons. And they secrete substances that promote the health of nerve cells. In other words, they're very useful to researchers hoping to ...

Tuberculosis: Researchers Uncover how Bacteria Burst our Cells

Tue, 11 Apr 2017 14:00:04 +0200

Scientists based in Vienna unveil the complex molecular structure that causes lethal infections by Mycobacterium tuberculosis (Mtb). Their findings might have implications for potential therapies against antibiotic-resistant tuberculosis. An international team of scientists across Europe, including ...

Recipharm appoints Henrik Stenqvist as new Chief Financial Officer

Tue, 11 Apr 2017 14:00:04 +0200

Recipharm AB today announced the appointment of Henrik Stenqvist as Recipharm’s new Executive Vice President and Chief Financial Officer, effective on April 24, 2017. He will be based at the company’s headquarters in Stockholm, Sweden and reports to Thomas Eldered, Chief Executive Officer of Recipha...

A moldable scaffold for bone

Tue, 11 Apr 2017 11:09:28 +0200

A team including researchers at Rensselaer Polytechnic Institute is developing a new material that can be used to replace skull bone lost to injury, surgery, or birth defect. The bioactive foam is malleable when exposed to warm saline, allowing surgeons to easily shape it to fit irregular defects in...

Breast milk as a weapon against cancer

Tue, 11 Apr 2017 07:00:11 +0200

In a project supported by the Austrian Science Fund FWF, scientists at the University of Graz modified and reinforced a host defence peptide from breast milk so as to enable it to specifically detect cancer cells. The active substance can then induce cell death. Research continues on this new therap...

Protein that increases effectiveness of vaccines detected

Tue, 11 Apr 2017 07:00:07 +0200

Researchers have discovered a protein they believe would help make vaccinations more effective and provide protection from other diseases such as cancer. The findings allows for greater understanding of how vaccine enhancers work and can best be used. Researchers from Boston University School of Med...

Rescue protein gives doomed cells a stay of 'execution'

Tue, 11 Apr 2017 07:00:05 +0200

A research team led by St. Jude Children's Research Hospital immunologists has discovered how a set of proteins delays the "executioner" machinery that kills damaged or infected cells in a process called necroptosis. The scientists believe the finding may have wide clinical implications if researche...

Grünenthal Group announced the acquisition of Adhesys Medical

Mon, 10 Apr 2017 14:00:03 +0200

The acquisition of Adhesys Medical and its highly innovative pipeline of surgical sealants, together with the underlying technology platform, allows Gruenenthal to tap into the global $1 billion surgical sealants market - This contributes to Gruenenthal's ambition to reach EUR2 billion in annual sal...

Solving medical 'cold cases' through genetics

Mon, 10 Apr 2017 14:00:00 +0200

Researchers have identified the genetic mutation responsible for one patient's serious health problems, finally solving a medical mystery that has endured for over 30 years. Thanks to this discovery, the researcher developed a therapy that could also help a lot of people who have problems related to...

Discovered: Novel Group of Giant Viruses

Mon, 10 Apr 2017 12:40:02 +0200

Viruses have a ubiquitous presence in the world. Their population is estimated to be 1031, 10 times greater than the nonillion (1030) of microbes on the planet—a figure that surpasses the number of stars in the Milky Way. Giant viruses are characterized by disproportionately large genomes and virion...

Structure of tuberculosis drug target determined

Mon, 10 Apr 2017 07:00:04 +0200

Rutgers University scientists have determined the three-dimensional structure of the target of the first-line anti-tuberculosis drug rifampin. They have also discovered a new class of potential anti-tuberculosis drugs that kill rifampin-resistant and multi-drug-resistant tuberculosis bacteria. Tuber...

Homing system delivers drugs to specific neurons

Mon, 10 Apr 2017 07:00:03 +0200

Biomedical engineers have developed a way to deliver drugs to specific types of neurons in the brain, providing an unprecedented ability to study neurological diseases while also promising a more targeted way to treat them. Drugs are the tool of choice for studying the connections between neurons, a...

Making spines from sea water

Mon, 10 Apr 2017 07:00:02 +0200

Some sea creatures cover themselves with hard shells and spines, while vertebrates build skeletons out of the same minerals. How do these animals get the calcium they need to build these strong mineral structures? Professors Lia Addadi and Steve Weiner of the Weizmann Institute of Science's Structur...

Feeding fat to fungi: Evidence for lipid transfer in arbuscular mycorrhiza

Mon, 10 Apr 2017 07:00:01 +0200

Nearly all organisms live in symbiosis with a vast, diverse array of microbes. Arbuscular mycorrhizal (AM) symbiosis is the interaction between plants and a group of fungi called Glomeromycota. Most land plants, including several crop species, are able to interact with these fungi, which have been l...

analytica Vietnam on a growth course

Fri, 07 Apr 2017 13:18:29 +0200

The fifth edition of analytica Vietnam, which was held from March 29 to 31, 2017, in the International Center for Exhibition (I.C.E) in Hanoi, produced an excellent overall result. 121 exhibitors from 17 countries, more nations than ever before, presented their products and solutions for the laborat...

No sugar coating, but sweet nonetheless

Fri, 07 Apr 2017 11:36:05 +0200

Complex neurotechnological devices are required to directly select and influence brain waves inside the skull’s interior. Although it has become relatively easy to implement the devices, researchers are still faced with challenges when trying to keep them running properly in living organisms over ti...

Unexpected protein structure findings could lead to new therapies

Fri, 07 Apr 2017 07:00:09 +0200

Scientists have determined unexpected characteristics of a key protein linked to blood pressure control and to nerve growth, pain control and heart tissue regeneration. The findings opens doors to potential new therapies to control cardiovascular disease and pain. The protein, called AT2, is one of ...

Deep sleep may act as fountain of youth in old age

Fri, 07 Apr 2017 07:00:07 +0200

As we grow old, our nights are frequently plagued by bouts of wakefulness, bathroom trips and other nuisances as we lose our ability to generate the deep, restorative slumber we enjoyed in youth. But does that mean older people just need less sleep? Not according to UC Berkeley researchers, who argu...

Researchers develop Marburg virus treatment effective five days after infection

Fri, 07 Apr 2017 07:00:03 +0200

An antibody treatment successfully protected nonhuman primates against the deadly Marburg and Ravn viruses even when given five days after becoming infected, according to the latest findings of a collaborative team from The University of Texas Medical Branch at Galveston, Mapp Biopharmaceutical Inc....

Newly discovered chemical reaction in eye may improve vision

Fri, 07 Apr 2017 07:00:01 +0200

A light-sensing pigment found in everything from bacteria to vertebrates can be biochemically manipulated to reset itself, an important therapeutic advantage, according to new research out of Case Western Reserve University School of Medicine. In a study researchers successfully used a modified form...