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Merck expands distribution agreement with Roche

Fri, 02 Dec 2016 09:41:37 +0100

Merck announced an expansion of its distribution alliance with Roche to include the polymerase chain reaction (PCR) and quantitative real-time PCR (qPCR) enzyme products of Kapa Biosystems, a company acquired by Roche in 2015. The addition of the Kapa portfolio strengthens Merck’s existing distribut...

New strategy may drop cancer's guard

Fri, 02 Dec 2016 06:00:23 +0100

A drug used now to treat Type 2 diabetes may someday help beat breast and ovarian cancers, but not until researchers decode the complex interactions that in some cases help promote tumors, according to Rice University scientists. Rice bioscientist Daniel Carson and alumna Micaela Morgado researched ...

Drug delivery modification sidesteps allergic responses

Fri, 02 Dec 2016 06:00:14 +0100

Biomedical engineers at Duke University have reconfigured a popular drug-delivery technology to evade immune responses that have halted some clinical trials. Polyethylene glycol, commonly known as PEG, is a polymer commonly found in commercial products from toothpaste to cosmetics, and also in pharm...

Watson-Marlow Fluid Technology Group acquires Aflex Hose Ltd

Fri, 02 Dec 2016 06:00:11 +0100

Watson-Marlow Fluid Technology Group has acquired Aflex Hose Limited and its subsidiary Aflex Hose USA LLC (Aflex) through its parent company Spirax-Sarco Engineering plc, for £61.4 million. Aflex, based in Halifax, England and with a sales/assembly operation in Pennsylvania, USA, specializes in the...

Danaher announces leadership appointment

Fri, 02 Dec 2016 06:00:01 +0100

Danaher Corporation announced that effective January 1, 2017, Rainer Blair has been promoted to Executive Vice President of Danaher Corporation, with responsibility for the Company's $5 billion Life Sciences platform. Mr. Blair, 52 years old, has served in a series of progressively more responsible ...

Psilocybin eases existential anxiety in people with life-threatening cancer

Thu, 01 Dec 2016 13:00:09 +0100

In a small double-blind study, Johns Hopkins researchers report that a substantial majority of people suffering cancer-related anxiety or depression found considerable relief for up to six months from a single large dose of psilocybin -- the active compound in hallucinogenic "magic mushrooms." The r...

Zedira receives funding for the development of transglutaminase inhibitors

Thu, 01 Dec 2016 13:00:07 +0100

Zedira announced today that the BMBF will grant additional 1.5 million Euros funding to the company within the highly competitive SME-Innovative program over the next three years. The aim of the project is for Zedira to develop small molecule tissue transglutaminase inhibitors that are orally bioava...

New insights into skin cells could explain why our skin doesn't leak

Thu, 01 Dec 2016 10:11:19 +0100

The discovery of the shape and binding capability of epidermal cells could explain how skin maintains a barrier even when it is shedding. The authors of the study say their new understanding of how epidermal cells form a barrier may explain the paradox of how we can shed them without compromising ou...

Potential new tool to aid breast cancer surgery

Thu, 01 Dec 2016 06:00:27 +0100

University of Adelaide researchers have developed an s that distinguishes breast cancer tissue from normal tissue - potentially allowing surgeons to be much more precise when removing breast cancer. The device could help prevent follow-up surgery, currently needed for 15-20% of breast cancer surgery...

Takeda to invest more than 100 million Euros in dengue vaccine manufacturing plant

Thu, 01 Dec 2016 06:00:25 +0100

Takeda Pharmaceutical Company Limited announced that it will invest more than 100 Million Euros to build a new manufacturing plant for its dengue vaccine candidate in Singen, Germany. This represents a major step by Takeda toward meeting important unmet needs in dengue prevention. According to the W...

Peptides as tags in fluorescence microscopy

Thu, 01 Dec 2016 06:00:15 +0100

The Biocenter of the University of Würzburg in close collaboration with the University of Copenhagen has developed an alternative approach to fluorescent tagging of proteins. The new probes are practicable and compatible with high-resolution microscopic procedures. Fluorescence microscopy visualize...

ZEISS and EPFL begin long-term research collaboration

Thu, 01 Dec 2016 06:00:01 +0100

ZEISS will support innovative research projects at the Swiss Federal Institute of Technology in Lausanne (École polytechnique fédérale de Lausanne, abbr. EPFL). The company will make one million euros available for new research projects in key technology fields such as biomedical research, medical d...

Breaking good

Thu, 01 Dec 2016 01:00:00 +0100

Sydney Grammar students, under the supervision of the University of Sydney and global members of the Open Source Malaria consortium, have reproduced an essential medicine in their high school laboratories. The drug, Daraprim, had been the subject of controversy when the price was hiked from US $13.5...

FDA Accepts the Biologics License Application for Avelumab for Priority Review

Wed, 30 Nov 2016 13:00:02 +0100

Merck and Pfizer Inc. announced that the US Food and Drug Administration (FDA) has accepted for Priority Review the Biologics License Application (BLA) for avelumab, which was submitted by EMD Serono, the biopharmaceutical business of Merck in the US and Canada. This review relates to avelumab’s pro...

Creation of micro muscles aids better understanding of muscle efficiency

Wed, 30 Nov 2016 13:00:01 +0100

A biomedical research scientist is taking the lead in the creation of muscle cells and micro muscles to test muscle efficiency in the laboratory - and he is able to carry out this new and innovative work thanks to the support he has received to get him back into science after a career break. Anthony...

Zika & Chikungunya Vaccine Development Boosted By Cash Injection

Wed, 30 Nov 2016 06:00:13 +0100

Themis Bioscience successfully closed a Series B financing round of 10 Mio Euro. The fresh capital will be used to complete a phase 2 clinical trial of its lead product, a vaccine candidate against Chikungunya fever. Further products that will benefit include the company's Zika virus vaccine whose d...

Successfully Treating Genetically Determined Autoimmune Enteritis

Wed, 30 Nov 2016 06:00:11 +0100

Using targeted immunotherapy, doctors have succeeded in curing a type of autoimmune enteritis caused by a recently discovered genetic mutation. This report comes from researchers at the Department of Biomedicine of the University of Basel and University Hospital Basel. Their results raise new possib...

Sometimes just watching hurts - and the signs of pain are seen in the brain

Wed, 30 Nov 2016 06:00:06 +0100

Some people claim to experience pain just watching something painful to happen. This is true especially of people suffering from complex regional pain syndrome (CRPS), a disabling chronic pain disorder in a limb. In CPRS patients, both own movements and just observing other persons' movements may ag...

Mysteries of enzyme mechanism revealed

Wed, 30 Nov 2016 06:00:04 +0100

An international research team led by the University of Leicester has made a breakthrough advance by trapping an intermediate in the mechanism of enzymes called heme peroxidases and determining its structure using a beam of neutrons from the heart of a nuclear reactor. The Leicester team members say...

Staph uses nitric oxide enzyme to colonize noses

Wed, 30 Nov 2016 06:00:00 +0100

Staph bacteria colonize nasal passages through a newly discovered function for a primeval biochemical mechanism. The interior of the nose is a prime dwelling place for some forms of staph. More than one-third of the population has a chronic presence of Staphylococcus aureus in their nostrils and sin...

SYGNIS AG reinforces its proteomics portfolio with two patents granted in Europe and China

Tue, 29 Nov 2016 12:25:15 +0100

SYGNIS AG announced it had been granted broad patents in Europe and China. The patent granted by the European Patent Office (EPO) titled: “Methods and Kits for Folding Proteins in the Presence of Linear or Branched Sugar Polymers” covers SYGNIS’ NVoy technology for use in protein folding application...

Zika-bearing mosquitoes quickly invade and adapt to new environments

Tue, 29 Nov 2016 06:00:06 +0100

The Zika-bearing mosquito Aedes aegypti is not only spreading rapidly but has shown a remarkable ability to adapt quickly to different locales and climates, according to Jeffrey Powell, professor of ecology and evolutionary biology and environmental health sciences. The mosquito species, which also ...

Targeting breast cancer metabolism to fight the disease

Mon, 28 Nov 2016 13:00:07 +0100

How does a cancer cell burn calories? New research from Thomas Jefferson University shows that breast cancer cells rely on a different process for turning fuel into energy than normal cells. "Our finding is part of a growing interest in studying the metabolic function of cancer," says Ubaldo Martine...

Enough is enough

Mon, 28 Nov 2016 13:00:04 +0100

The transcription factor Nanog plays a crucial role in the self-renewal of embryonic stem cells. Previously unclear was how its protein abundance is regulated in the cells. Researchers at the Helmholtz Zentrum München and the Technical University of Munich, working in collaboration with colleagues f...

Breaking new territory analyzing DNA modifications in glioblastoma

Mon, 28 Nov 2016 13:00:03 +0100

Using state-of-the-art molecular biology and statistical approaches, researchers at Dartmouth's Norris Cotton Cancer Center (NCCC) have identified the functional role of two distinct DNA modifications in glioblastoma (GBM) tissues. The signature of one of these pattern disruptions in particular, 5hm...

Tosoh to Increase Production Capacity of Liquid Chromatography Separation and Purification Media

Mon, 28 Nov 2016 11:52:09 +0100

Tosoh Corporation has announced that it will be increasing the production capacity of its Toyopearl liquid chromatography separation and purification media at its Nanyo Complex, in Shunan, Yamaguchi Prefecture. The nearly 50% production capacity increase is in response to growing global demand for p...

analytica 2018: Preparations for the upcoming exhibition are underway

Mon, 28 Nov 2016 06:00:15 +0100

Exhibitors can now register for analytica 2018. As the leading international trade fair for the analysis, laboratory technology and biotechnology industry, analytica has been a gathering for decision-makers and users in the laboratory community for 50 years. The next edition of analytica takes place...

Depression in Young People Affects the Stomach, Anxiety the Skin

Mon, 28 Nov 2016 06:00:13 +0100

Mental disorders and physical diseases frequently go hand in hand. For the first time, psychologists at the University of Basel and Ruhr University Bochum have identified temporal patterns in young people: arthritis and diseases of the digestive system are more common after depression, while anxiety...

Cholesterol an Important Piece of the Puzzle for Fat-Burning

Mon, 28 Nov 2016 06:00:09 +0100

Gut bacteria play a little-understood role in the body’s energy balance, which is influenced by diet. However, the crucial nutritional components are unknown. A team at the Technical University of Munich (TUM) was able to demonstrate for the very first time that mice without gastrointestinal microbi...

Total and Corbion form a Joint Venture in bioplastics

Fri, 25 Nov 2016 13:00:04 +0100

Total and Corbion are joining forces to develop bioplastics by creating a 50/50 joint venture to produce and market polylactic (PLA) polymers. The two partners plan to build a world-class PLA polymerization plant with a capacity of 75,000 tons per year at Corbion’s site in Thailand that already has ...

Missed Connections

Fri, 25 Nov 2016 13:00:03 +0100

Studies of brain activity typically draw their findings from measurement averages across entire groups of subjects. But new research out of UC Santa Barbara that highlights a novel method of characterizing and comparing the brain dynamics in individuals may signal a shift in that approach. While UCS...

Bringing silicon to life

Fri, 25 Nov 2016 10:55:53 +0100

A new study is the first to show that living organisms can be persuaded to make silicon-carbon bonds--something only chemists had done before. Scientists at Caltech "bred" a bacterial protein to make the man-made bonds--a finding that has applications in several industries. Molecules with silicon-ca...

Multi-organ platform for risk assessment of nanomaterials

Fri, 25 Nov 2016 10:13:17 +0100

Nanomaterials are already part of everyday life in our modern society. New applications, along with continuously rising quantities being produced, have led to an increased exposure to nanomaterials for both people and the environment. Predicting the behaviour of nanomaterials in organisms and extens...

The birth of the brightest red glowing protein

Fri, 25 Nov 2016 06:00:11 +0100

The brightest red fluorescent protein ever, mScarlet, has just been engineered by researchers at the University of Amsterdam, the Institut de Biologie Structurale, IBS (CEA/CNRS/University Grenoble Alpes) and the European Synchrotron (ESRF) in France. mScarlet can be used to monitor the activity in ...

The full spectrum of lab technology - in May 2017 in Hannover

Fri, 25 Nov 2016 06:00:05 +0100

Less than six months to go until the beginning of LABVOLUTION/BIOTECHNICA 2017, and the objective is already clear: The European trade fair for the full spectrum of laboratory technology is primed to prove the aptness of its new course next spring. Following a series of far-reaching changes, the eve...

Cancer cells 'talk' to their environment, and it talks back

Thu, 24 Nov 2016 13:00:09 +0100

Interactions between an animal cell and its environment, a fibrous network called the extracellular matrix, play a critical role in cell function, including growth and migration. But less understood is the mechanical force that governs those interactions. A multidisciplinary team of Cornell engineer...

Brain activity predicts the force of your actions

Thu, 24 Nov 2016 13:00:06 +0100

Researchers have found a link between the activity in nerve clusters in the brain and the amount of force generated in a physical action, opening the way for the development of better devices to assist paralysed patients. A clear link between the activity in nerve clusters in the brain and the amoun...

Rapid synthesis towards optically active alpha-aminocarbonyl therapeutics

Thu, 24 Nov 2016 10:19:12 +0100

A team of organic chemists at ITbM, Nagoya University, has developed a new reaction to directly install amines into carbonyl compounds using their unique phase-transfer catalyst. This unprecedented method leads to the rapid formation of optically active (chiral) α-aminocarbonyls, which are structura...

First-ever Buyer-Seller Forum at analytica Vietnam

Thu, 24 Nov 2016 06:00:18 +0100

Having the right contacts and a good network are indispensible in the business world. To help exhibitors and visitors make business contacts that suit them to a tee, for the first time ever analytica 2017 will feature a platform for pre-arranged meetings at a Buyer-Seller Forum. The Buyer-Seller For...

Catching molecular dance moves in slow motion by adding white noise

Thu, 24 Nov 2016 06:00:15 +0100

In extreme slow-motion, a molecule of medicine entering a cell receptor would look a little like a Soyuz space capsule docking at the International Space Station. It would brake here, boost there; rotate, translate and then, with a light jolt, lock into place. In real time, large molecules interact ...

Mystery of how plants produce oxygen soon solved

Thu, 24 Nov 2016 06:00:09 +0100

With the help of experimental studies on molecular level, researchers are acquiring increased knowledge on how plants form oxygen from water molecules. An international research team has now found a way to visualise this reaction in high-resolution images of photosystem II. "This work is a breakthro...

With a little help from my fungus

Wed, 23 Nov 2016 10:23:29 +0100

Plants are constantly challenged by hungry animals and infectious microbes. Tomato plants, for example, are often infested with little worms that feed on their roots. A fungus can help them to better defend themselves against these attacks. In the future, farmers and gardeners might benefit from the...

Medigene appoints Dr. Thomas Taapken as Chief Financial Officer

Wed, 23 Nov 2016 06:00:13 +0100

Medigene AG announced that its Supervisory Board has appointed Dr. Thomas Taapken as Chief Financial Officer (CFO) as of 1 January 2017.  As a member of Executive Management working at the Munich headquarters of Medigene, Dr. Taapken will assume the CFO responsibilities which were temporarily taken ...

No fear! Neuropeptide may aid targeted anxiety therapy

Wed, 23 Nov 2016 06:00:12 +0100

The targeted control of biochemical processes and neuronal signalling pathways using the messenger substance neuropeptide Y could help in the future treatment of anxiety disorders. Palpitations, sweating and sleep problems – most people have already experienced symptoms of anxiety. As a response to ...

New antiretroviral drugs decrease chances of HIV sexual transmission

Wed, 23 Nov 2016 06:00:06 +0100

More than 2 million people got infected by human immunodeficiency virus (HIV) in 2015, being sexual transmission the main channel of infection. Researchers from the Infections of the Respiratory Tract and in Immunocompromised Patients group of the Bellvitge Biomedical Research Institute (IDIBELL), l...

Arrowhead Pharmaceuticals Announces closing of collaboration agreement with Amgen

Wed, 23 Nov 2016 06:00:03 +0100

Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) announced that the license and collaboration agreement between Arrowhead and Amgen covering the novel RNAi ARC-LPA program has closed, following early termination of the waiting period. About ARC-LPA ARC-LPA is designed to reduce production of apolipopr...

Turning Back the Aging Clock

Tue, 22 Nov 2016 06:00:18 +0100

Researchers from Caltech and UCLA have developed a new approach to removing cellular damage that accumulates with age. The technique can potentially help slow or reverse an important cause of aging. Led by Nikolay Kandul, senior postdoctoral scholar in biology and biological engineering in the labor...

Targeting the “un-targetable”

Tue, 22 Nov 2016 06:00:16 +0100

Triple negative breast cancers (TNBC) are so named because they lack common genetic “target” mutations that can be easily treated with specific cancer drugs. However Deborah Lannigan , Ph.D., and colleagues investigated a new target involved in TNBC called RSK. They demonstrated that RSK can help ca...

Dissecting bacterial infections at the single-cell level

Tue, 22 Nov 2016 06:00:12 +0100

Technological advances are making the analysis of single bacterial infected human cells feasible, Würzburg researchers have used this technology to provide new insight into the Salmonella infection process. Infectious diseases are a leading cause of mortality worldwide. The development of novel the...

Updating embryo research guidelines

Mon, 21 Nov 2016 13:00:06 +0100

With advancing lab technology perhaps calling into question a longstanding guideline that prohibits experimentation on human embryos older than 14 days, scientists and ethicists gathered at Harvard Law School recently to discuss whether and how that stricture should be revised. Some speakers at the ...