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Vitamin A orange maize improves night vision

Thu, 27 Oct 2016 07:00:15 +0200

A new study has found that vitamin A-biofortified orange maize significantly improves visual functions in children. The study was conducted among school-aged children (4 to 8 years old) in rural Zambia. Children who ate orange maize showed improved night vision within six months. Their eyes adapted ...

Evotec announces its intent to acquire Cyprotex PLC

Thu, 27 Oct 2016 07:00:10 +0200

Evotec AG announced that it has made an offer to acquire Cyprotex PLC, a specialist pre-clinical contract research organisation in ADME-Tox and DMPK. Cyprotex serves the industry's increasing requirement for earlier drug screening, regulatory requirements and reducing the reliance on animal testing....

First-time reconstruction of infectious bat influenza viruses

Thu, 27 Oct 2016 07:00:06 +0200

Now a team at the Institute for Virology of the Medical Center – University of Freiburg, Germany, together with scientists from Switzerland and the USA, report a break-through in isolating a bat influenza virus by reconstituting fully functional bat influenza viruses in the laboratory. Unexpectedly,...

Seeking balanced networks

Wed, 26 Oct 2016 14:00:10 +0200

Neurons adjust their synapses by altering the synthesis of hundreds of proteins to regulate synaptic strength and network activity. Learning and memory formation are based on our brain’s ability to adjust and regulate neuronal network activity. Neurons communicate at specialized structures known as...

Agendia expands its business activities in Germany

Wed, 26 Oct 2016 14:00:06 +0200

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, announces the expansion of its business activities in Germany. The Company has launched the “BRIDGE” patient initiative to enable more physicians and their patients to access the additional benefits of itsMamma...

Driving mosquito evolution to fight malaria

Wed, 26 Oct 2016 14:00:05 +0200

One of the frustrations of fighting malaria is that mosquitoes evolve resistance to the insecticides used to kill them. Now researchers from Exeter University in the United Kingdom and the University of California, Berkeley, propose using insect repellents along with insecticides to extend the lifet...

Parasitic plants may form weapons out of genes stolen from hosts

Wed, 26 Oct 2016 14:00:02 +0200

Sneaky parasitic weeds may be able to steal genes from the plants they are attacking and then use those genes against the host plant, according to a team of scientists. In a study, researchers detected 52 incidences of the nonsexual transfer of DNA -- known as horizontal gene transfer, or HGT -- fro...

Here comes the long-sought-after iron-munching microbe

Wed, 26 Oct 2016 11:20:03 +0200

A microbe that ‘eats’ both methane and iron: microbiologists have long suspected its existence, but were not able to find it - until now. Researchers at Radboud University and the Max Planck Institute for Marine Microbiology in Bremen discovered a microorganism that couples the reduction of iron to ...

Mixing energy drinks, alcohol may affect adolescent brains like cocaine

Wed, 26 Oct 2016 10:59:26 +0200

Drinking highly caffeinated alcoholic beverages triggers changes in the adolescent brain similar to taking cocaine, and the consequences last into adulthood as an altered ability to deal with rewarding substances, according to a Purdue University study. Richard van Rijn, an assistant professor of me...

How does the brain in schizophrenia work?

Wed, 26 Oct 2016 10:59:22 +0200

The brain of people suffering from schizophrenia works differently than those of healthy subjects – but how? Looking for the mechanism behind these differences, researcher from the Central Institute of Mental Health (CIMH) in Mannheim and the University of Philadelphia use brain scans to find new an...

Calcium Induces Chronic Lung Infections

Wed, 26 Oct 2016 10:58:36 +0200

The bacterium Pseudomonas aeruginosa is a life-threatening pathogen in hospitals. About ten percent of all nosocomial infections, in particular pneumonia, are caused by this pathogen. Researchers from the University of Basel’s Biozentrum, have now discovered that calcium induces the switch from acut...

The gene of autumn colors

Wed, 26 Oct 2016 02:00:00 +0200

In plants, the pigment chlorophyll plays a central role in photosynthesis: the process of converting sunlight to energy. This process involves creating a flow of electrons by removing one from a molecule and transferring it to another. The first step happens when an electron is transferred from chlo...

Sartorius Continues to Grow by Strong Double Digits

Tue, 25 Oct 2016 21:40:37 +0200

Sartorius closed the first nine months of 2016 with significant double-growth rates for sales revenue and earnings. "Both divisions are continuing to grow faster than their respective markets," stated Group CEO Dr. Joachim Kreuzburg, giving a positive summary of the Group's nine-month performance. "...

Inflammation Triggers Unsustainable Immune Response to Chronic Viral Infection

Tue, 25 Oct 2016 21:40:09 +0200

Scientists at the University of Basel discovered a fundamental new mechanism explaining the inadequate immune defense against chronic viral infection. These results may open up new avenues for vaccine development. In the course of an infection or upon vaccination, specialized cells of our immune sys...

Precision medicine test helps guide breast cancer patients' chemotherapy decision

Tue, 25 Oct 2016 21:39:52 +0200

One of the earliest widespread applications of precision medicine in cancer care is helping patients and physicians decide whether chemotherapy is needed, a new study finds. Researchers looked at a test available to help assess the risk of breast cancer recurrence and whether chemotherapy is likely ...

Sunovion Pharmaceuticals completes acquisition of Cynapsus Therapeutics

Tue, 25 Oct 2016 21:39:28 +0200

Sunovion Pharmaceuticals Inc. (“Sunovion”) and Cynapsus Therapeutics Inc. (“Cynapsus”) announced that Sunovion has completed, through its wholly owned subsidiary, Sunovion CNS Development Canada ULC (the “Purchaser”), the previously announced acquisition of Cynapsus (the “Acquisition”). The Acquisit...

DNA damage response protein

Tue, 25 Oct 2016 21:39:16 +0200

Researchers at Vanderbilt University and Vanderbilt University Medical Center have determined that a previously uncharacterized protein called ETAA1 is a “replication stress response protein” with an essential role in maintaining the integrity of the genome. The finding by David Cortez , Ph.D., Walt...

First cyborg bacteria developed

Mon, 24 Oct 2016 11:38:30 +0200

ETH scientists have constructed bacteria in which growth can be controlled fully automatically by a computer. The interface between computer and bacteria is based on red and green light. The approach could help to optimise the biotechnological production of molecules. Researchers at ETH Zurich’s Dep...

Advances in Alzheimer’s research

Mon, 24 Oct 2016 07:00:07 +0200

The research team of Dr. Caghan Kizil at the DFG-Center for Regenerative Therapies Dresden (CRTD) - Cluster of Excellence at the TU Dresden, achieved a major advance in Alzheimer’s research. They showed how a diseased vertebrate brain can naturally react to Alzheimer’s pathology by forming more neur...

Imaging technique maps serotonin activity in living brains

Mon, 24 Oct 2016 07:00:01 +0200

Serotonin is a neurotransmitter that's partly responsible for feelings of happiness and for mood regulation in humans. This makes it a common target for antidepressants, which block serotonin from being reabsorbed by neurons after it has dispatched its signal, so more of it stays floating around the...

A look at the 'marijuana' receptor

Fri, 21 Oct 2016 14:00:05 +0200

Researchers have the clearest picture yet of the receptor that causes the "high" associated with marijuana. The three-dimensional image of cannabinoid receptor 1, revealed October 20 in Cell, reveals how molecules like THC bind to cannabinoid receptor 1, which is found to be embedded in the surface ...

Bacterial Genes Boost Current in Human Cells

Fri, 21 Oct 2016 07:00:13 +0200

Duke University biomedical engineers have harvested genes for ion channels from bacteria that, with a few tweaks, can create and enhance electrical signaling in human cells, making the cells more electrically excitable.   The technique could one day be used to treat cardiac arrhythmia or to restore ...

MorphoSys Receives Clinical Milestone for Start of Phase 1 Trial with Novel Cancer Antibody

Fri, 21 Oct 2016 07:00:09 +0200

MorphoSys AG announced that it has received a milestone payment from Novartis in connection with the initiation of a phase 1 clinical trial with a novel HuCAL antibody. The antibody will be tested in the field of cancer. Financial details were not disclosed. "This is the 13th therapeutic antibody ba...

Evotec and UCB sign multi-year CNS pharmacology agreement

Fri, 21 Oct 2016 07:00:07 +0200

Evotec AG announced a collaboration with UCB to provide a broad range of in vitro pharmacology services. Under the terms of the three-year agreement, Evotec will support UCB's in vitro pharmacology team in drug discovery projects across multiple target classes, particularly in the CNS space. Key act...

Portable smartphone laboratory detects cancer

Thu, 20 Oct 2016 12:08:08 +0200

Washington State University researchers have developed a low-cost, portable laboratory on a smartphone that can analyze several samples at once to catch a cancer biomarker, producing lab quality results. The research team, led by Lei Li, assistant professor in the School of Mechanical and Materials ...

L.B. Bohle: Robin Meier new Head of Technology Center

Thu, 20 Oct 2016 07:00:11 +0200

All it took were two short discussions to sort out the details: Robin Meier (30) joined L.B. Bohle Maschinen + Verfahren GmbH as Manager Scientific Operations on 15 August 2016. Robin Meier, who was born in Essen, explains the pragmatic decisions as follows: “I knew the company from my doctoral stud...

Biochemistry: Combining two catalytic worlds

Thu, 20 Oct 2016 07:00:08 +0200

Chemical and biological catalysts tend to require very different reaction conditions, making their combination challenging. Researchers of the Ruhr-Universität Bochum have succeeded in taking this hurdle by using a special gel matrix to compartmentalize both types of catalysts. The results obtained ...

A dangerous bond

Thu, 20 Oct 2016 07:00:02 +0200

Helicobacter pylori is a bacterium that can colonize the human stomach – sometimes with fatal consequences. A research group led by Prof. Markus Gerhard of the Technical University of Munich (TUM) and Assistant Professor Dr. Bernhard B. Singer of the Institute for Anatomy at the Faculty of Medicine ...

PerkinElmer Elects Samuel Chapin to Board of Directors

Wed, 19 Oct 2016 07:00:05 +0200

PerkinElmer, Inc. announced that Samuel R. Chapin has been elected to the Company's Board of Directors. "I am pleased to welcome Samuel to our Board, as he brings extensive experience in strategic advisory, mergers and acquisitions, and deal financing for a wide range of transactions, along with dee...

From the plant to the microreactor

Wed, 19 Oct 2016 07:00:03 +0200

Scientists at the Leibniz-Institute of Plant Biochemistry (IPB) in Halle/Saale (Germany) have fully elucidated the biosynthesis of carnosic acid. This discovery allowed the plant researchers around Prof. Alain Tissier to produce the economically valuable plant material by biotechnological means in y...

Peptides vs. superbugs

Wed, 19 Oct 2016 07:00:00 +0200

Several peptides have an antibacterial effect - but they are broken down in the human body too quickly to exert this effect. Empa researchers have now succeeded in encasing peptides in a protective coat, which could prolong their life in the human body. This is an important breakthrough because pept...

Merck Expands Biotech Production Capacity in Spain

Tue, 18 Oct 2016 14:00:01 +0200

Merck KGaA, Darmstadt, Germany, a leading science and technology company, today celebrated a major expansion of its biotech plant in Tres Cantos, Madrid, Spain, resulting in a 50% increase in the facility’s production capacity. Tres Cantos is the main site of Merck KGaA, Darmstadt, Germany, for the ...

Scientists create novel imaging technique with potential for medical diagnostics

Tue, 18 Oct 2016 07:00:09 +0200

A unique new imaging method, called "polarized nuclear imaging" - combining powerful aspects of both magnetic resonance imaging and gamma-ray imaging and developed by two physicists in the University of Virginia's departments of Physics and Radiology has potential for new types of high-resolution me...

Researchers develop DNA-based single-electron electronic devices

Tue, 18 Oct 2016 07:00:07 +0200

Nature has inspired generations of people, offering a plethora of different materials for innovations. One such material is the molecule of the heritage, or DNA, thanks to its unique self-assembling properties. Researchers at the Nanoscience Center (NSC) of the University of Jyväskylä and BioMediTec...

Artificial enzyme for asymmetric synthesis using a synthetic chiral polymer

Tue, 18 Oct 2016 07:00:06 +0200

Enzymes, high-molecular-weight chiral polymeric compounds, are complex biological catalysts. Capture of the substrate molecule, catalyzing the reaction, and release of the product are three important events performed by enzymes. In order to accomplish these important events using a synthetic catalys...

analytica Anacon India and India Lab Expo 2016 in the starting blocks

Mon, 17 Oct 2016 10:56:15 +0200

analytica Anacon India and India Lab Expo, leading trade fairs for laboratory technology, analysis, biotechnology and diagnostics is scheduled from October 20 to 22 at the HITEX Exhibition Center, Hyderabad. The trade fairs will bring together manufacturers, suppliers, business experts and buyers on...

Crystal clear imaging

Mon, 17 Oct 2016 10:12:13 +0200

Detailing the molecular makeup of materials -- from solar cells to organic light-emitting diodes (LEDs) and transistors, and medically important proteins -- is not always a crystal-clear process. To understand how materials work at these microscopic scales, and to better design materials to improve ...

Silver nanoparticle concentration too low to be harmful in water supply

Mon, 17 Oct 2016 07:00:10 +0200

Silver nanoparticles have a wide array of uses, one of which is to treat drinking water for harmful bacteria and viruses. But do silver nanoparticles also kill off potentially beneficial bacteria or cause other harmful effects to water-based ecosystems? A new paper from a team of University of Misso...

Cocoa compound linked to some cardiovascular biomarker improvements

Mon, 17 Oct 2016 07:00:08 +0200

To the tantalizing delight of chocolate lovers everywhere, a number of recent studies employing various methods have suggested that compounds in cocoa called flavanols could benefit cardiovascular health. Now a systematic review and meta-analysis of 19 randomized controlled trials (RCTs) of cocoa co...

Going viral: Insights on Zika

Mon, 17 Oct 2016 07:00:07 +0200

The Zika virus (ZIKV) is not a new contagion; researchers have known about the virus since the 1950s. However, not much was known about the virus until recent outbreaks cropped up with debilitating impacts. While searching for targets that could be used to generate antibodies against the virus, biol...

Sleeping cells' survival instincts: A double-edged sword?

Mon, 17 Oct 2016 07:00:05 +0200

For researchers who study aging, a central riddle remains: If the human body has evolved to protect itself, why are cells unable to cope with the challenges associated with getting old? By creating a new experimental model to study quiescent -- or "sleeping" -- human cells, Drexel University researc...

Jellyfish help scientists to fight food fraud

Fri, 14 Oct 2016 11:11:10 +0200

Animals feeding at sea inherit a chemical record reflecting the area where they fed, which can help track their movements, according to a new study by scientists from the University of Southampton. Chemical testing of the source of marine food products could be a powerful tool to help to fight food ...

Merck Sets its Sights on 2018 and Outlines Future Strategic Roadmap

Fri, 14 Oct 2016 07:00:08 +0200

Merck informed analysts and investors at its 2016 Capital Market Day about the progress it has made in achieving its objectives up to the year 2018. In addition, CEO Stefan Oschmann and CFO Marcus Kuhnert provided a look at the period after 2018, the year which marks the company’s 350th anniversary....

Efficiency plus versatility

Fri, 14 Oct 2016 07:00:07 +0200

Antimicrobial cutting boards. Flame-retardant carpets. Friction-resistant bearings. Engineered surfaces add value to the things we use, providing extra layers of safety, easing their operation, preserving their quality or adding utility. At UC Santa Barbara, materials researchers are looking to grea...

Scientists find new metabolic pathways to resist viruses

Fri, 14 Oct 2016 07:00:02 +0200

Viral infection is one of the leading medical challenges of the 21st Century, ranging from the Hepatitis C Virus (HCV) epidemic affecting 3% of the global population, to recent outbreaks of West Nile, Zika, and Ebola viruses. Viruses are parasites that lack the basic metabolic machinery needed to re...

PhoreMost Ltd and University of Cambridge collaborate

Fri, 14 Oct 2016 07:00:00 +0200

PhoreMost Ltd (PhoreMost), a biopharmaceutical company dedicated to drugging ‘undruggable’ disease targets, has entered into a research collaboration with the laboratory of Professor David Rubinsztein at the University of Cambridge. The groups will study and translate essential cellular mechanisms o...

A step forward in building functional human tissues

Thu, 13 Oct 2016 11:04:54 +0200

Toward the ultimate goal of engineering human tissues and organs that can mimic native function for use in drug screening, disease modeling, and regenerative medicine, a Wyss Institute team led by Core Faculty member Jennifer Lewis, Sc.D., has made another foundational advance using three-dimensiona...

Physicists demonstrate method to study atoms critical to medicine

Thu, 13 Oct 2016 07:00:15 +0200

UCLA physicists have shown that shining multicolored laser light on rubidium atoms causes them to lose energy and cool to nearly absolute zero. This result suggests that atoms fundamental to chemistry, such as hydrogen and carbon, could also be cooled using similar lasers, an outcome that would allo...

SCIENION opens French subsidiary Cellenion with focus on controlled cell dispensing technologies

Thu, 13 Oct 2016 07:00:06 +0200

SCIENION AG, a provider for ultra-low volume liquid handling applications, announced that its new subsidiary Cellenion S.A.S. started operations in Lyon, France back in May 2016. Cellenion focuses on controlled cell dispensing technologies in the fields of bioprinting and single-cell dispensing. R&D...

Energy hijacking pathway found within photosynthesis

Wed, 12 Oct 2016 14:00:03 +0200

An unexpected source of inefficiency within a photosynthetic enzyme has been identified by scientists. The issue also adversely affects the performance of devices which are used to model artificial photosynthesis - a biomimicry process which is central to efforts to generate sustainable fuel by conv...