Preview: Forthcoming article in Acta Crystallographica Section F: Structural Biology and Crystallization Communications
Forthcoming article in Acta Crystallographica Section F Structural Biology Communications
Acta Crystallographica Section F: Structural Biology Communications is a rapid all-electronic journal, which provides a home for short communications on the crystallization and structure of biological macromolecules. Structures determined through structur
Crystal structure of truncated human coatomer protein complex subunit ζ1 (Copζ1)
Selective targeting of the ζ1 subunit of the human coatomer protein complex I (Copζ1) is a promising avenue for anticancer therapy, as knockouts of ζ1 have been shown to specifically kill both proliferating and nondividing tumour-cell populations. In order to provide a structural basis for rational drug design, the high-resolution crystal structure of Copζ1 is reported.