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Preview: Best Syndication - Genetics and Stem Cells

Best Syndication - Genetics and Stem Cells





 



Juxtapid (lomitapide) gains FDA approval

Thu, 27 Dec 2012 03:56:04 +0000

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(Best Syndication News) - The U.S. Food and Drug Administration (FDA) approved Juxtapid (lomitapide) to treat a rare homozygous familial hypercholesterolemia (HoFH) disorder. Juxtapid should lower the low-density lipoprotein (LDL) cholesterol levels, the total cholesterol, apolipoprotein B, and non-high-density lipoprotein (non-HDL) cholesterol. The drug should be prescribed in conjunction with a low fat diet and other lipid reduction treatments.

In the United States, around one in one million people have HoFH. People with the rare condition do not effectively remove “bad” LDL cholesterol from their body. This puts HoFH individuals at an increased risk for heart attacks and death, often before the age of 30.

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Scientist identify More Genetic causes of Coronary Artery Disease

Mon, 03 Dec 2012 04:00:52 +0000

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(Best Syndication News) - A large group of international scientists, including scientists from Standford University School of Medicine, has identified 15 new genetic areas that are related to coronary artery disease. With these new findings, there are now 46 genetic links related to heart disease. The research findings will be published in the December 2 online edition of Nature Genetics.

Coronary atherosclerosis, another name for plaque build-up in the artery wall of the heart vessels, is a condition that can cause a person to suffer chest pain or a heart attack. According the U.S. Centers for Disease Control, heart disease ranks as the leading cause of death in the United States.

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Hereditary High Blood Cholesterol not Identified and Treated Effectively

Fri, 02 Nov 2012 04:45:54 +0000

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(Best Syndication News) - A research study from the University of Copenhagen and Herleve Hospital found that more Danes than previously thought have hereditary high blood cholesterol, and the condition is not being treated optimally. The study results were published in The Journal of Clinical Endocrinology & Metabolism.

Dr Børge Nordestgaard, clinical professor at the Faculty of Health and Medical Sciences and senior physician at Herlev Hospital, said of the 69,000 Danes investigated, they found that 1 out of 137 people in Denmark had hereditary high blood cholesterol.

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New Treatment for Brain Swelling

Wed, 23 May 2012 07:29:39 +0000

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(Best Syndication News) European researchers say they have come up with a new treatment to save the life of people suffering from swelling of the brain. Their method can safely manipulate the blood vessels in the brain to allow for a periodic opening of the channels between the blood vessels and the brain cell lining.

The goal is to relieve acute pressure on the brain caused by stroke, brain injury, tumors, or other conditions that can cause swelling. Over the years, there has been little change in the treatment of this condition, according to Dr. Matthew Campbell, of the Ocular Genetics Unit at Trinity College Dublin.

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Coffee and Short Exercise Program Alters DNA

Thu, 08 Mar 2012 06:53:40 +0000

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(Best Syndication News) Scientists say that a small amount of exercise by people who are normally sedentary can change their DNA “immediately.” Caffeine could change the structure of the DNA of muscles in a similar way.

Juleen Zierath of Karolinska Institutet in Sweden says that our muscles are really “plastic.” Muscles adapt to what we do. While the underlying genetic code of the muscle isn’t changed, the molecular structure of the DNA is chemically and structurally altered, according to Zierath.

“If you don't use it, you lose it, and this is one of the mechanisms that allows that to happen," Zierath explained. The exercise appears to genetically reprogram the muscle tissue for strength.

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Breast Cancer Cells Transformed into Stem Cells via Radiation Treatments

Tue, 14 Feb 2012 05:46:33 +0000

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(Best Syndication News) Researchers say that radiation treatments can turn cancer tumor cells into “treatment resistant breast cancer stem cells.”

Researchers from the UCLA Department of Radiation Oncology at the Jonsson Comprehensive Cancer Center, say that if they can stop the transformation of these cancer cells into stem cells, radiation treatments could be even more effective.

Although half of the tumor cells are killed-off during radiation treatments, some that remain morph into these stem cells that are resistant to the treatments, according to Dr Frank Pajonk, who is also a scientist with the Eli and Edythe Broad Center of Regenerative Medicine at UCLA.

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Scientists investigate new ways to combat constantly changing Flu Virus

Sat, 28 Jan 2012 10:12:33 +0000

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(Best Syndication News) A University of Georgia research team is gaining headway in their attempt to understand the constantly evolving influenza virus. Ralph Tripp, a Georgia Research Alliance Eminent Scholar and Chair of Animal Health Vaccine Development in the UGA College of Veterinary Medicine, says that interfering with the way viruses replicate may provide a way to treat the flu.

Viruses replicate by attaching themselves to a host cell, and turning that cell into a factory. Tripp says that influenza binds with sugars found on the surface of host cells in the lung and respiratory tract. The virus then injects its genetic information into the nucleus of the cell and virus replication begins.

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Mesothelioma - Genetic Mutation increases Cancer Risk

Mon, 29 Aug 2011 18:21:39 +0000

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(Best Syndication News) - Researchers believe they have found a genetic link between developing mesothelioma and Melanoma of the eye. Mutations in the BAP1 gene is associated with an increased risk for developing these two cancers. The study is in the online August 28, 2011 edition of Nature Genetics.

The study was funded by the National Cancer Institute (NCI) and was conducted by researchers from the University of Hawaii Cancer Center, Honolulu, and Fox Chase Cancer Center, Philadelphia.

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Master Switch that controls fat found

Tue, 17 May 2011 09:32:02 +0000

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(Best Syndication News) Researchers at the King’s College in London and the University of Oxford found a gene that controls fat cells. It was already known that the KLF14 gene is linked to type-2 diabetes and cholesterol levels, but researchers now know it controls much more.

They say there is an “association” between the KLF14 gene and the expression levels of multiple distant genes found in fat tissue. The KLF14 gene is a “master switch”. It controls the body-mass index (obesity), cholesterol, insulin and glucose levels.

The metabolic traits are inherited from the mother. “The copy of KLF14 from the father is switched off, meaning that the copy from the mother is the active gene,” the King’s College reported Monday.

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Reprogrammed Sperm Cells Could Cure Type 1 Diabetes

Mon, 13 Dec 2010 11:16:45 +0000

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(Best Syndication News) Scientists from the Georgetown University Medical Center (GUMC) say that men with type-1 diabetes may be able to grow their own insulin producing cells.

Researchers reported their findings to an audience at the 50th annual meeting of the American Society of Cell Biology conference in Philadelphia. They found that human spermatogonial stem cells (SSCs) extracted from testicular tissue can change into insulin-secreting beta islet cells.

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Scientists turns Human Skin into Blood

Sun, 07 Nov 2010 21:08:20 +0000

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Best Syndication News

(Best Syndication News) - Scientists from McMaster University Stem Cell and Cancer Research Institue which is part of the Michael G. DeGroote School of Medicine made a breakthrough discovery to turn a person's skin into human blood. The groundbreaking research is be published in the current issue of the science journal 'Nature.'

Mick Bhatia, who is the scientific director at the McMaster Stem Cell and Cancer Research Institute along with his colleagues demonstrated that making blood from skin is a direct conversion process. The scientists showed that this worked using human skin as well. They tested duplicated the process of turning skin into blood and it works with all ages or people. Hope for clinical trials studies are anticipated by the researchers to be as soon as 2012.

If the process of making blood from human skin develops into a medical application it could be possible for people could make their own blood from their skin from anything from blood needed for surgical procedures, cancer treatments and certain anemia conditions.

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Gene Patent Lawsuit Settle In Favor Of ACLU

Thu, 01 Apr 2010 21:37:59 +0000

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Gene in Relation to Double Helix

(Best Syndication News) Over the past couple decades the patent laws have been changing to include patents on life, genes and even processes and ideas. Earlier this week Judge Robert Sweet (U.S. District Court) ruled that seven patent relating to the BRCA 1 and BRCA 2 genes were invalid.

This is a blow to the company which submitted the patents, Myriad Genetics. The company says they will appeal the decision to the Court of Appeals for the Federal Circuit and will continue and “vigorously defend this litigation”. Myriad points out that there are still 164 claims remaining under these seven patents which were not challenged.

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Insulin and Glucose Regulation Genes Identified

Sun, 17 Jan 2010 20:15:57 +0000

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[Best Syndication News] Researchers of an international research consortium have identified 13 new genetic variants related to blood glucose, insulin secretion, and insulin resistance. Out of the newly identified genes, five of variants increase the risk of a person developing type 2 diabetes. These findings were largely the results of two studies that were conducted by the Meta-Analyses of Glucose and Insulin Related Traits Consortium (MAGIC). The study was funded partly by the National Institutes of Health and the studies will in the January 17th, 2010 online edition of Nature Genetics.

The researchers analyzed around 2.5 million gene variants in the 21 genome-wide association studies (GWAS) of around 46,186 individuals that were not diagnosed with diabetes, but had been tested for glucose and insulin regulation. The found that the most common variation was the single nucleotide polymorphism (SNP) which is a single base pair change in one part of the building blocks of DNA.

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Documentary 'The Mermaid Girl: The Last Six Months' Special on TLC

Sat, 12 Dec 2009 01:29:30 +0000

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[Best Syndication News] A special documentary will air called 'The Mermaid Girl: The Last Six Months' on TLC channel this Sunday, December 13th, which will follow the last months of Shiloh Pepin, who was called a living mermaid because her legs are fused together from a birth defect. The show was to cover her reaching the milestone of turning 10 years old. Shortly after her birthday unfortunately she fell ill and died on October 23, 2009, at Maine Medical Center in Portland, Maine.

Pepin was born with a condition called Sirenomelia, which is also called Mermaid Syndrome. This is an extremely rare birth deformity where the legs are fused together which gives the appearance of the person having a mermaid tail.

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Antibiotic Kills Cancer Stem Cells

Fri, 14 Aug 2009 04:06:17 +0000

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(Best Syndication News) In an effort that would have made Thomas Edison envious, scientists at the Massachusetts Institute of Technology (MIT) tested 16,000 chemicals to find one that would kill cancer stem cells. This is important because some conventional chemotherapy treatments are unable to kill cancer stem cells that reside in tumors.

Out of the 16,000 natural and commercial chemical compounds the researchers found 32 that worked. Out of those they found one “clear winner” that is readily available. That compound is salinomycin, an antibiotic that disturbs the cell potassium balance. .

According to research published in the August 13th 2009 issue of the journal Cell it is uncertain how it works or if it will ever be available as a treatment, but scientists will certainly use it as a tool for manipulating cancer stem cell numbers and for observing the effects on cancer's spread and progression.

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Sperm Created By Embryonic Stem Cells

Thu, 09 Jul 2009 19:08:32 +0000

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Sperm - source: wik

(Best Syndication News) Scientists in the United Kingdom say they have created new sperm cells from embryonic stem cells (ESC). The research could lead to more than a solution for male infertility, but could also help explain why children with leukemia later become infertile and explanations to other genetic abnormalities (see video below).

In the July 8th 2009 academic journal Stem Cells and Development, Professor Karim Nayernia and colleagues at the Newcastle University and the NorthEast England Stem Cell Institute (NESCI) report that they have created human sperm in the laboratory. This will lead to a better understanding of “infertility in men” and the effect of toxins on reproduction.

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Gene Therapy And Stem Cells Can Cure Genetic Diseases - Fanconi anemia Cystic fibrosis, Sickle cell anemia Rett syndrome and mor

Tue, 02 Jun 2009 03:47:40 +0000

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Fanconi anemia - Source: RadsWiki

(Best Syndication News) Amazing research from the Salk Institute has demonstrated that human genetic diseases can be cured using a combination of gene therapy and stem cells. In the past this research has been conducted on mice, but now Salk colleagues and researchers around the world have cured diseased human cells.

Doctor Juan-Carlos Izpisúa Belmonte, Ph.D., professor in the Expression Laboratory and director of the Center of Regenerative Medicine in Barcelona (CMRB), Spain says they have used induced pluripotent stem (iPS) cells, not embryonic stem cells, to cure Fanconi anemia (FA) in human cells. The doctor used the word “cure” to describe their findings.

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Psoriasis Risk Factor For Diabetes Hypertension And Death – Harvard Study Links High Blood Pressure and Type-2 With Skin Disease

Mon, 20 Apr 2009 21:38:45 +0000

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Psoriasis source - wik

(Best Syndication News) Psoriasis may affect more than the skin and may lead to high blood pressure and even diabetes. People with Psoriasis are at an increased risk for death, developing diabetes and hypertension (high blood pressure), according to Harvard Medical School Researchers.

Doctor Abrar A. Qureshi, M.D., M.P.H., of Brigham and Women's Hospital and Harvard Medical School, Boston compared women with psoriasis and women without it using data from the Nurses' Health Study II, a group of female nurses who were between the ages of 27 and 44 in 1991. The study included 78,061 women.

What is Psoriasis?

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Dr. Oz and Michael J. Fox talk about Parkinson’s disease on Oprah

Wed, 01 Apr 2009 00:09:41 +0000

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Always Looking Up CD - Fox

[Best Syndication News] ‘The Oprah Winfrey’ show had an interesting show with Dr. Oz and Michael J. Fox discussing Parkinson’s disease. Fox has been living with Parkinson’s disease and has shown on the show today that even though he is suffering from this nervous system disease he doesn’t stop living his life. He has had Parkinson’s for the past 18 years.

Fox’s wife Tracy Pollen has been his rock he said to Dr. Oz. Fox meant that as a compliment. They seemed to really love each other and have been married for 20 years.

Dr. Oz asked Pollen how their relationship has changed since being diagnosed with Parkinson’s. She said that when they were first married he was working all the time, which has changed and he now has more time with her. The children said that he is shaky. Pollen said that their children are extremely empathetic. Fox said that sometimes it can be difficult if he has to do something with them at school. Fox seemed to value his time with his children.

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Neanderthal Genome Mapping Research Presents At AAAS – German Scientists Close To Finding Genetic Links To Humans

Mon, 16 Feb 2009 02:05:04 +0000

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Johannes Krause, Adrian Briggs, Richard E. Green,
Svante Pääbo (from left to right)

(Best Syndication News) Scientists at the Max Planck Institute for Evolutionary Anthropology in Munich Germany say they have mapped nearly 63 percent of the 3.2 billion base pairs in the Neanderthal genome. An announcement that they have completed their “first draft” of the genome was made at the 2009 Annual Meeting of the American Association for the Advancement of Science (AAAS).

Using novel methods developed by Professor Svante Pääbo, Director of the Institute’s Department of Evolutionary Anthropology, the team sequenced more than one billion DNA fragments extracted from three Croatian Neanderthal fossils. They believe that this research will help clarify the evolutionary relationship between humans and the prehistoric Neanderthal.

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