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MedWorm: Radiology



MedWorm.com provides a medical RSS filtering service. Over 7000 RSS medical sources are combined and output via different filters. This feed contains the latest news and research in Radiology



Last Build Date: Mon, 28 Mar 2016 01:15:40 +0100

 



Carotid siphon morphology: Is it associated with posterior communicating aneurysms?

Sat, 26 Mar 2016 20:48:02 +0100

CONCLUSIONS: This case-control study shows that the carotid siphon morphology seems not to be related to PComA aneurysm formation or rupture. PMID: 27012777 [PubMed - as supplied by publisher] (Source: Interventional Neuroradiology)

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Calendar

Sat, 26 Mar 2016 09:34:56 +0100

(Source: Ultrasound in Medicine and Biology)



Contents

Sat, 26 Mar 2016 09:34:56 +0100

(Source: Ultrasound in Medicine and Biology)



Editorial Advisory Board

Sat, 26 Mar 2016 09:34:56 +0100

(Source: Ultrasound in Medicine and Biology)



Masthead

Sat, 26 Mar 2016 09:34:56 +0100

(Source: Ultrasound in Medicine and Biology)



Quantitative evaluation of left ventricular volume and function in middle‐aged healthy chinese people with 3 Tesla MRI

Sat, 26 Mar 2016 09:34:34 +0100

ConclusionThe left ventricular volume and function differs in women compared with men in the middle‐aged population, and these parameters have a tendency of decrease with ageing. J. Magn. Reson. Imaging 2016. (Source: Journal of Magnetic Resonance Imaging)

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Accelerated phase contrast flow imaging with direct complex difference reconstruction

Sat, 26 Mar 2016 09:34:23 +0100

ConclusionThe proposed method achieves improved accuracy over several state‐of‐the‐art methods for velocity reconstruction with highly accelerated ‐space data. Magn Reson Med, 2016. © 2016 Wiley Periodicals, Inc. (Source: Magnetic Resonance in Medicine)



Coarctation of the aorta diagnosed by cardiac computed tomography angiography in a 49-year-old man presenting with acute myocardial infarction

Sat, 26 Mar 2016 09:34:19 +0100

We report the case of a 49-year-old man with acute myocardial infarction and diagnosis of severe aortic coarctation in concomitance with a three-dimensional computed tomography scan. (Source: The International Journal of Cardiovascular Imaging)






Relationship of basal-septal fibrosis with LV outflow tract obstruction in hypertrophic cardiomyopathy: insights from cardiac magnetic resonance analysis

Sat, 26 Mar 2016 09:34:19 +0100

In conclusion, a significant association was observed between LVOT obstruction and basal septal fibrosis by LGE-CMR in HCM patients. In addition to negative impact of basal-septal fibrosis, basal-septal hypertrophy and preserved global LV contractility may be associated with the pathophysiological features of LVOT obstruction. (Source: The International Journal of Cardiovascular Imaging)



Epicardial myocardial strain abnormalities may identify the earliest stages of arrhythmogenic cardiomyopathy

Sat, 26 Mar 2016 09:34:19 +0100

Abstract The aim of this cohort study was to evaluate the value of echocardiographic multilayer strain analysis in the identification of arrhythmogenic cardiomyopathy (AC) in its earliest stages in which sudden cardiac death can occurs. Twenty seven asymptomatic relatives of AC probands (mean age 39.6 ± 19.5 years, 37 % male) with a desmosomal pathogenic mutation but no additional criteria for AC (group II) were compared to age and sex-matched healthy controls (group I). In addition, 70 patients harboring a pathogenic desmosomal mutation with “definitive” diagnosis of AC (group IV), and 19 subjects with “borderline” diagnosis (group III) were also studied. A standard echocardiographic evaluation plus left (LV) and right ventricular global and regional transmural, end...

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Are changes in the extent of left ventricular dyssynchrony as assessed by speckle tracking associated with response to cardiac resynchronization therapy?

Sat, 26 Mar 2016 09:34:19 +0100

Abstract Echocardiographic assessment of left ventricular (LV) dyssynchrony is used to predict response to cardiac resynchronization therapy (CRT). However, the association between reduction in the extent of speckle tracking based LV-dyssynchrony and echocardiographic response to CRT has not been explored yet. The aim of this study was to assess the changes in the extent of LV dyssynchrony as a result of CRT and its association with echocardiographic response to CRT in a large consecutive series of patients. We studied 138 patients with standard CRT indication. Time-based speckle tracking longitudinal strain (maximal delay between 6-segments in 4-chamber view) was performed to assess LV-dyssynchrony at baseline and after a mean follow-up of 22 ± 8 months. Echocardiographic CR...



Computed tomography perfusion imaging may predict cognitive impairment in patients with first-time anterior circulation transient ischemic attack

Sat, 26 Mar 2016 09:34:19 +0100

Abstract To determine whether computed tomography perfusion imaging (CTPI)-derived parameters are associated with vascular cognitive impairment (VCI) in patients with transient ischemic attack (TIA). Patients with first-time anterior circulation TIA (diagnosed within 24 h of onset) and normal cognition, treated between August 2009 and August 2014 at the Department of Neurology of Chengdu Military General Hospital, China, were analyzed retrospectively. Patients underwent whole-brain CTPI within 1 week of TIA to detect cerebral blood volume (CBV), cerebral blood flow (CBF), mean transit time (MTT) and time to peak (TTP) in the ischemic region. Based on cognitive function assessment 4 weeks after TIA, using the Montreal cognitive assessment (MoCA) and mini mental state examinatio...



Evaluation for abdominal aortic aneurysms is justified in patients with thoracic aortic aneurysms

Sat, 26 Mar 2016 09:34:19 +0100

Abstract Aortic aneurysms are a significant cause of mortality, and the presence of multiple aneurysms may affect treatment plans. The purpose of this study was to determine the frequency of abdominal aortic aneurysms (AAAs) in patients with thoracic aortic aneurysms (TAAs) and to establish whether patient specific factors, such as gender and comorbidities, influenced the frequency of AAAs, thereby indicating if and when abdominal aortic evaluation is justified. Electronic medical records were reviewed from 1000 patients with a computed tomography (CT) angiogram of the chest and abdomen and a clinical diagnosis of TAA from Cardiac Surgery clinic between 2008 and 2013. 538 patients with history of aortic intervention, dissection, rupture or trauma were excluded. The frequency of A...



18 F-FDG PET/CT in the diagnosis of prosthetic valve endocarditis

Sat, 26 Mar 2016 09:34:19 +0100

Abstract Recent studies have shown promising results using 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in the diagnosis of prosthetic valve endocarditis (PVE). However, previous studies did not include negative controls. The aim of this study was to compare 18F-FDG-uptake around prosthetic aortic valves in patients with and without PVE and to determine the diagnostic performance of 18F-FDG PET/CT in the diagnosis of PVE. 18F-FDG PET/CT examinations in patients with a prosthetic aortic valve performed 2008–2014 were retrieved. Eight patients with a final diagnosis of definite PVE were included in the analysis of the diagnostic performance of 18F-FDG PET/CT. Examinations performed on suspicion of malignancy in patients without PVE (n ...



The advantages of live/real time three-dimensional transesophageal echocardiography during assessments of pulmonary stenosis

Sat, 26 Mar 2016 09:34:19 +0100

This study provides evidence of the incremental value of using 3D-TEE rather than 2D-TEE during assessments of PS, specifically in cases where special conditions (pregnancy, pulmonary regurgitation, and concomitant atrial septal defects) cause recordings of the transvalvular peak gradient to be inaccurate. Therefore, 3D-TEE should be used as a complementary imaging tool to 2D-TEE during routine echocardiographic examinations. (Source: The International Journal of Cardiovascular Imaging)

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Sequential radial and circumferential strain and oxidative stress assessment in dogs with tachycardia-induced cardiac dysfunction

Sat, 26 Mar 2016 09:34:19 +0100

Abstract Quantitative analysis of left ventricular (LV) deformation based on two-dimensional speckle tracking echocardiography (2D STE) has increasingly been used to assess segmental and global function because conventional echocardiography is influenced by tethering effects of adjacent myocardium and cardiac translational motion. Hypothesis: (1) 2D STE can be useful to detect subtle regional changes in the LV contractility during development of tachycardia-induced cardiomyopathy (TIC) to heart failure in awake dog; (2) oxidized glutathione (GSSG) and reduced glutathione (GSH) levels are associated with the development of its respective segmental wall motion abnormalities (WMA). 6 healthy canine female Beagles were examined using 2D STE myocardial strain analysis before and for 8...



Epicardial fat thickness: distribution and association with diabetes mellitus, hypertension and the metabolic syndrome in the ELSA-Brasil study

Sat, 26 Mar 2016 09:34:19 +0100

In conclusion, the amount of EFT in this large multiethnic population is smaller than reported in other populations. EFT reference values varied across demographic and clinical variables, EFT associations with cardiometabolic variables being largely explained by age, sex, ethnicity and central obesity. Although EFT can help identify individuals at increased cardiometabolic risk, it will likely have a limited additional role compared to current risk stratification strategies. (Source: The International Journal of Cardiovascular Imaging)



Sequential combination of k‐t principle component analysis (PCA) and partial parallel imaging: k‐t PCA GROWL

Fri, 25 Mar 2016 23:00:00 +0100

ConclusionBy sequentially combining the GRAPPA operator and k‐t PCA, the proposed k‐t PCA GROWL method outperformed k‐t PCA/SENSE in both reconstruction speed and accuracy, suggesting that k‐t PCA GROWL is a better combination scheme than k‐t PCA/SENSE. Magn Reson Med, 2016. © 2016 Wiley Periodicals, Inc. (Source: Magnetic Resonance in Medicine)



Quantitative 3D magnetic resonance elastography: Comparison with dynamic mechanical analysis

Fri, 25 Mar 2016 23:00:00 +0100

Conclusions3D MRE and DMA showed excellent consistency over a wide range of frequencies and stiffnesses. Magn Reson Med, 2016. © 2016 Wiley Periodicals, Inc. (Source: Magnetic Resonance in Medicine)



Characterization of anomalous relaxation using the time‐fractional Bloch equation and multiple echo T2*‐weighted magnetic resonance imaging at 7 T

Fri, 25 Mar 2016 23:00:00 +0100

ConclusionsWe were able to fit multiple echo time MRI data with high accuracy using the developed model. Parameters of the model likely capture information on microstructural and susceptibility‐induced changes in the human brain. Magn Reson Med, 2016. © 2016 Wiley Periodicals, Inc. (Source: Magnetic Resonance in Medicine)

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Evaluation of cisterna chyli diameter with MRI in patients with chronic kidney disease

Fri, 25 Mar 2016 23:00:00 +0100

ConclusionCC diameter is observed to be larger in patients with CKD than in the normal population. Additionally, CC diameter increased with more severe stages of CKD. According to our results, CC diameter might be used as an MRI marker to indicate the presence and severity of CKD. J. Magn. Reson. Imaging 2016. (Source: Journal of Magnetic Resonance Imaging)



Parameter optimization for reproducible cardiac 1H‐MR spectroscopy at 3 Tesla

Fri, 25 Mar 2016 23:00:00 +0100

ConclusionUsing approaches designed to optimize SNR and minimize the variation in inter‐average signal intensities and frequencies/phases, a protocol was developed to perform cardiac MR spectroscopy on a clinical 3T system with high reproducibility. J. Magn. Reson. Imaging 2016. (Source: Journal of Magnetic Resonance Imaging)



A wearable navigation display can improve attentiveness to the surgical field

Fri, 25 Mar 2016 23:00:00 +0100

Conclusions Attentiveness to the surgical field can be improved with the use of a light-weight, untracked, wearable display. A through-the-lens display performs better than a peripheral display, and both perform better than a computer monitor. Eye dominance should be considered when positioning the display. (Source: International Journal of Computer Assisted Radiology and Surgery)



Context region discovery for automatic motion compensation in fluoroscopy

Fri, 25 Mar 2016 23:00:00 +0100

Conclusion In this work, we open a new paradigm to provide dynamic real-time guidance for TAVI without user interventions, specially in case of severe occlusion where conventional tracking methods are challenged. (Source: International Journal of Computer Assisted Radiology and Surgery)



Alignment of the lower extremity mechanical axis by computer-aided design and application in total knee arthroplasty

Fri, 25 Mar 2016 23:00:00 +0100

Conclusions The navigation template produced through mechanical axis of lower extremity may provide a relative accurate and simple method for TKA. (Source: International Journal of Computer Assisted Radiology and Surgery)

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Deformable registration of trans-rectal ultrasound (TRUS) and magnetic resonance imaging (MRI) for focal prostate brachytherapy

Fri, 25 Mar 2016 23:00:00 +0100

Conclusions The proposed method provides a promising framework for TRUS–MRI registration in focal prostate brachytherapy. (Source: International Journal of Computer Assisted Radiology and Surgery)



Patient-individualized boundary conditions for CFD simulations using time-resolved 3D angiography

Fri, 25 Mar 2016 23:00:00 +0100

Conclusion The presented methods have the potential to accurately estimate patient-specific boundary conditions from a single dedicated rotational scan. (Source: International Journal of Computer Assisted Radiology and Surgery)



Intraoperative application of hand-held structured light scanning: a feasibility study

Fri, 25 Mar 2016 23:00:00 +0100

Conclusions The results of this preliminary study indicate that structured light scanning could be applied accurately and safely in a surgical environment. This could result in a variety of applications for these scanners in image-guided interventions as intraoperative imaging and registration tools. (Source: International Journal of Computer Assisted Radiology and Surgery)



Utility of multiplex real-time PCR in the diagnosis of extrapulmonary tuberculosis

Fri, 25 Mar 2016 23:00:00 +0100

Conclusion PCR can play an important role in rapid and accurate diagnosis of extrapulmonary tuberculosis. IS6110 alone is an effective target in our part of the country. (Source: The Brazilian Journal of Infectious Diseases)



Age-related changes in thickness of anterior lower uterine segment in normal singleton pregnancy during 20–35 weeks’ gestation

Fri, 25 Mar 2016 23:00:00 +0100

Conclusions The anterior LUS gradually thinned from Th0cm to Th3cm at 20–35 weeks’ gestation. Th3cm became increasingly thin between 20–23 and 28–31 weeks’ gestation. (Source: Journal of Medical Ultrasonics)

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Commentary on CT-guided percutaneous core-needle biopsy of pancreatic masses: comparison of the standard mesenteric/retroperitoneal versus the trans-organ approaches

Fri, 25 Mar 2016 23:00:00 +0100

In this issue of Clinical Radiology, Tseng et al. present their results of percutaneous core biopsy of the pancreas using computed tomography (CT) guidance. When a patient needs tissue confirmation of a pancreatic lesion they are often referred for endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA). Is this the right approach or should CT guided pancreatic biopsy be used? (Source: Clinical Radiology)



Post-Operative Spine Stereotactic Body Radiotherapy (SBRT): A critical review to guide practice

Fri, 25 Mar 2016 23:00:00 +0100

Post-operative stereotactic body radiotherapy (SBRT) for metastatic spinal tumors is increasingly being performed in clinical practice. Whereas the fundamentals of SBRT practice for intact spinal metastases are established, there are as yet no comprehensive practice guidelines for the post-operative indication. In particular, there are unique considerations for patient selection and treatment planning specific to post-operative spine SBRT that are critical for safe and effective management. The purpose of this critical review is to discuss the rationale for treatment, describe those factors impacting surgical decision making, introduce modern surgical trends, and summarize treatment outcomes for both conventional post-operative conventional external beam radiotherapy and post-operative spi...



Are Diagnostic Radiographers Image Acquisition Experts Within the General Radiographic Environment?

Fri, 25 Mar 2016 23:00:00 +0100

This article challenges whether diagnostic radiographers are image acquisition experts after the introduction of direct digital radiography (DDR). (Source: Journal of Medical Imaging and Radiation Sciences)



Process evaluation of treatment times in a large radiotherapy department

Fri, 25 Mar 2016 23:00:00 +0100

The Department of Health (DH) recognises access to appropriate and timely radiotherapy (RT) services as crucial in improving cancer patient outcomes, especially when facing a predicted increase in cancer diagnosis. There is a lack of ‘real-time’ data regarding daily demand of a linear accelerator, the impact of increasingly complex techniques on treatment times, and whether current scheduling reflects time needed for RT delivery, which would be valuable in highlighting current RT provision. (Source: Radiography)

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Will all patients with suspicion of prostate cancer undergo multiparametric MRI before biopsy in the future?

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: April 2016 Source:Diagnostic and Interventional Imaging, Volume 97, Issue 4 Author(s): O. Rouvière (Source: Diagnostic and Interventional Imaging)



Prostate Embolization as an Alternative to Open Surgery in Patients with Large Prostate and Moderate to Severe Lower Urinary Tract Symptoms

Fri, 25 Mar 2016 23:00:00 +0100

Conclusions PAE provides sustained short-, medium-, and long-term control for LUTS in patients with BPH and PV > 100 cm3. (Source: Journal of Vascular and Interventional Radiology)



Optimal HMPAO α value for Lassen’s correction algorithm obscured by statistical noise

Fri, 25 Mar 2016 23:00:00 +0100

Conclusion Despite this, adoption of the new, smaller α value of 0.5 would be more useful clinically in regaining the contrast between low-flow and high-flow areas of the brain. (Source: Annals of Nuclear Medicine)



Characterization of anomalous relaxation using the time-fractional Bloch equation and multiple echo T2 *-weighted magnetic resonance imaging at 7 T.

Fri, 25 Mar 2016 23:00:00 +0100

CONCLUSIONS: We were able to fit multiple echo time MRI data with high accuracy using the developed model. Parameters of the model likely capture information on microstructural and susceptibility-induced changes in the human brain. Magn Reson Med, 2016. © 2016 Wiley Periodicals, Inc. PMID: 27016390 [PubMed - as supplied by publisher] (Source: Magnetic Resonance in Medicine)

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Quantitative 3D magnetic resonance elastography: Comparison with dynamic mechanical analysis.

Fri, 25 Mar 2016 23:00:00 +0100

CONCLUSIONS: 3D MRE and DMA showed excellent consistency over a wide range of frequencies and stiffnesses. Magn Reson Med, 2016. © 2016 Wiley Periodicals, Inc. PMID: 27016276 [PubMed - as supplied by publisher] (Source: Magnetic Resonance in Medicine)



Sequential combination of k-t principle component analysis (PCA) and partial parallel imaging: k-t PCA GROWL.

Fri, 25 Mar 2016 23:00:00 +0100

CONCLUSION: By sequentially combining the GRAPPA operator and k-t PCA, the proposed k-t PCA GROWL method outperformed k-t PCA/SENSE in both reconstruction speed and accuracy, suggesting that k-t PCA GROWL is a better combination scheme than k-t PCA/SENSE. Magn Reson Med, 2016. © 2016 Wiley Periodicals, Inc. PMID: 27016133 [PubMed - as supplied by publisher] (Source: Magnetic Resonance in Medicine)



Accelerated phase contrast flow imaging with direct complex difference reconstruction.

Fri, 25 Mar 2016 23:00:00 +0100

CONCLUSION: The proposed method achieves improved accuracy over several state-of-the-art methods for velocity reconstruction with highly accelerated (k,t)-space data. Magn Reson Med, 2016. © 2016 Wiley Periodicals, Inc. PMID: 27016025 [PubMed - as supplied by publisher] (Source: Magnetic Resonance in Medicine)



Digital Mammograms Could Also Reveal Heart Disease Risk

Fri, 25 Mar 2016 21:46:48 +0100

This study demonstrates that accurate cardiovascular risk can be determined by evaluating the extent of calcification in blood vessels seen on digital mammograms, without the use of any additional radiation or risk. These exciting findings will allow women to be screened for the two most frequent life-threatening diseases at once - breast cancer and cardiovascular disease - (and allow) for determination of cardiovascular risk in a large population of women who might otherwise not get this potentially life-saving information.”   SOURCE: http://bit.ly/1MESUa8 JACC: Imaging, released March 24, 2016. -- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website....



Evaluation of the effects of positioning and configuration on contrast to noise ratio in the quality control of a 3D Accuitomo 170 dental cone beam CT system.

Fri, 25 Mar 2016 19:17:01 +0100

CONCLUSIONS: The effects of phantom configuration and positioning on CNR measurements for dental CBCT QC were investigated, and possible remedial tolerances suggested. PMID: 27008106 [PubMed - as supplied by publisher] (Source: Dentomaxillofacial Radiology)



The value of thyroid shielding in intraoral radiography.

Fri, 25 Mar 2016 19:17:01 +0100

CONCLUSIONS: For the exposures in the upper anterior region, thyroid shield results in an important dose reduction for the thyroid. For the other exposures, thyroid shield augments little to the reduction achieved by rectangular collimation. The use of thyroid shield is to be advised when performing upper anterior radiography. PMID: 27008105 [PubMed - as supplied by publisher] (Source: Dentomaxillofacial Radiology)



Lyme: Fight Harder For Science and End This War

Fri, 25 Mar 2016 18:09:08 +0100

I just had a flashback. When I was diagnosed with Lyme, I knew little about it. I went to the first infectious disease doctor with my bullseye still present, asking lots of questions. Among them, are you sure this three weeks of doxycycline is enough. He smiled, and with his eyes fixed on his computer, he said, "Yes, it's more than enough. In fact, I could just tell you to take ten days but then you'd come back later if anything went haywire and ask why I didn't give you twenty-one." He looked up, "Call me if anything goes crazy." A month later, I called. I woke up with a very sore throat and fever two days before my brother's wedding and a gland in my neck that felt like a pulsating grape. It was movable but scarily large. He said if it didn't go down in a few weeks, to let him know. It d...



Evaluation of DNA damage induced by Auger electrons from (137)Cs.

Fri, 25 Mar 2016 17:58:03 +0100

CONCLUSIONS: The result supports the existing perception that the biological effects by internal and external exposure by (137)Cs are equivalent. PMID: 27010691 [PubMed - as supplied by publisher] (Source: International Journal of Radiation Biology)



Triple targeting of Auger emitters using octreotate conjugated to a DNA-binding ligand and a nuclear localizing signal.

Fri, 25 Mar 2016 17:58:03 +0100

CONCLUSIONS: The DNA-binding properties of PNO and its affinity for SSTR suggests that it could potentially be used for tumour-specific delivery of PIH labelled with an Auger emitter in SSTR expressing tumours. PMID: 27010622 [PubMed - as supplied by publisher] (Source: International Journal of Radiation Biology)



Hypoxia-inducible proteins HIF1α and lactate dehydrogenase LDH5, key markers of anaerobic metabolism, relate with stem cell markers and poor post-radiotherapy outcome in bladder cancer.

Fri, 25 Mar 2016 17:58:03 +0100

CONCLUSIONS: HIF1α and LDH5 are markers of poor outcome in patients with bladder cancer treated with radiotherapy. Blockage of anaerobic metabolism may prove of importance in clinical radiotherapy. PMID: 27010533 [PubMed - as supplied by publisher] (Source: International Journal of Radiation Biology)



A stochastic cascade model for Auger-electron emitting radionuclides.

Fri, 25 Mar 2016 17:58:03 +0100

Authors: Lee BQ, Nikjoo H, Ekman J, Jönsson P, Stuchbery AE, Kibédi T Abstract To benchmark a Monte Carlo model of the Auger cascade that has been developed at the Australian National University (ANU) against the literature data. The model is applicable to any Auger-electron emitting radionuclide with nuclear structure data in the format of the Evaluated Nuclear Structure Data File (ENSDF). Schönfeld's algorithms and the BrIcc code were incorporated to obtain initial vacancy distributions due to electron capture (EC) and internal conversion (IC), respectively. Atomic transition probabilities were adopted from the Evaluated Atomic Data Library (EADL) for elements with atomic number, Z = 1-100. Atomic transition energies were evaluated using a relativistic Dirac-Fock method. A...

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Disruption of the ovarian follicle reservoir of prepubertal rats following prenatal exposure to a continuous 900-MHz electromagnetic field.

Fri, 25 Mar 2016 17:58:03 +0100

Authors: Türedi S, Hancı H, Çolakoğlu S, Kaya H, Odacı E Abstract The effects on human health of electromagnetic field (EMF) have begun to be seriously questioned with the entry into daily life of devices establishing EMF, such as cell phones, wireless fidelity, and masts. Recent studies have reported that exposure to EMF, particularly during pregnancy, affects the developing embryo/fetus. The aim of this study was therefore to examine the effects of exposure to continuous 900-Megahertz (MHz) EMF applied in the prenatal period on ovarian follicle development and oocyte differentiation. Six pregnant Sprague Dawley rats were divided equally into a non-exposed control group (CNGr) and a group (EMFGr) exposed to continuous 900-MHz EMF for 1 h daily, at the same time every day, o...



Development of multimodal neuroimaging markers for neurological disorders - Part 2.

Fri, 25 Mar 2016 17:39:04 +0100

Authors: Wong KK, Wang D, Liang P PMID: 27002913 [PubMed - as supplied by publisher] (Source: Journal of X-Ray Science and Technology)



Altered regional homogeneity in epileptic patients with infantile spasm: A resting-state fMRI study.

Fri, 25 Mar 2016 17:39:04 +0100

Authors: Tan Z, Li Y, Zang D, Zhang H, Zhao C, Jiang H, Chen Y, Cao D, Chen L, Liao J, Chen Q, Luan G Abstract Infantile spasm (IS) syndrome is an age-related epileptic encephalopathy that occurs in children. The purpose of this study was to investigate regional homogeneity (ReHo) changes in IS patients. Resting-state fMRI was performed on 11 patients with IS, along with 35 age- and sex-matched healthy subjects. Group comparisons between the two groups demonstrate that the pattern of regional synchronization synchronization in IS patients is changed. Decreased ReHo values were found in default mode network, bilateral motor-related areas and left occipital gyrus of the patient group. Increased ReHo was found in regions of cingulum, cerebellum, supplementary motor area and brain deep...



The changes of HRV in refractory epilepsy: The potential index to predict the onset of epilepsy in children.

Fri, 25 Mar 2016 17:39:04 +0100

In this study, we examine the potential of heart rate variability (HRV) as an efficient tool for predicting the onset of epilepsy in children. We totally collected 53 seizures EEG and ECG data using Video - EEG - ECG monitoring system. We then separated the ECG data into three segments: ten-minute before onset of each seizure, five-minute before onset of each seizure, and five-minute from the onset of each seizure. After the HRV parameters in all segments were calculated, we compared the differences between pre-ictal period and ictal period. We found that the values of meanHR, LF and LF/HF were greater in onset period. And the values of meanRR and the HF were less in ictal period. And it presented the similar changes when seizures occurred in the daytime and seizures occurred in the nightt...



Cerebral activation effects of acupuncture using Zusanli (ST36) and Yanglingquan (GB34) points based on regional homogeneity indices: A resting-state fMRI study.

Fri, 25 Mar 2016 17:39:04 +0100

CONCLUSION: The results of our neuroimaging study suggest that the combination of acupoints could more widely activate areas of the brain compared to a single acupoint. Additionally, the combination of acupoints can activate some new brain areas and generate new curative effects. PMID: 27002910 [PubMed - as supplied by publisher] (Source: Journal of X-Ray Science and Technology)

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Differentially disrupted functional connectivity of the subregions of the amygdala in Alzheimer's disease.

Fri, 25 Mar 2016 17:39:04 +0100

Authors: Wang Z, Zhang M, Han Y, Song H, Guo R, Li K Abstract The amygdala is an important brain area involved in cognitive procession and emotional regulation. Previous studies have typically considered the amygdala as a single structure, which likely masks contribution of individual amygdala subdivisions. Actually, the amygdala is heterogeneous and composed of structurally and functionally distinct nuclei, which may present different connectivity patterns and predict to relevant cognitive deficits in Alzheimer's disease (AD). However, little is known about functional connectivity of amygdala subregions in the resting state in AD subjects. Here, we employed resting-state functional MRI (fMRI) to examine functional connectivity changes of subregions comparing the AD patients with t...



Basal vein in the posterior incisural space: An anatomical comparison based on autopsy, digital subtraction angiography and computed tomographic venography.

Fri, 25 Mar 2016 17:39:04 +0100

CONCLUSIONS: Preoperative DSA and CTV are useful in the design of individualized surgical approaches and the preservation of the basal vein in the posterior incisural space. PMID: 27002908 [PubMed - as supplied by publisher] (Source: Journal of X-Ray Science and Technology)



Development of multimodal neuroimaging markers for neurological disorders - Part 1.

Fri, 25 Mar 2016 17:39:04 +0100

Authors: Wong KK, Wang D, Liang P PMID: 27002907 [PubMed - as supplied by publisher] (Source: Journal of X-Ray Science and Technology)



Influence of the X-ray beam quality on the dose increment in CT with iodinated contrast medium.

Fri, 25 Mar 2016 17:39:04 +0100

CONCLUSIONS: The dosimetric method for contrast-enhanced CT can be applied to all CT scanners by adopting average simulative parameters and by carrying out a simple measurement with a series of iodine contrast solutions. The novel experimental methodology introduced can provide a direct measurement of iodine attenuation properties. PMID: 27002906 [PubMed - as supplied by publisher] (Source: Journal of X-Ray Science and Technology)



Quantification of fat deposition in bone marrow in the lumbar vertebra by proton MRS and in-phase and out-of-phase MRI for the diagnosis of osteoporosis.

Fri, 25 Mar 2016 17:39:04 +0100

Authors: Zhang L, Li S, Hao S, Yuan Z Abstract The goal for this study was to investigate if proton MRS (1H-MRS) and out-of-phase and in-phase MRI can quantify the fat deposition in bone marrow within the lumbar vertebra that can be used to distinguish well between osteoporosis patients and healthy control subjects. 68 subjects participated in this study. The diagnostic results from dual-energy x-ray absorptiometry served as the gold standard, which was able to separate the subjects into osteoporosis (38 subjects) and non-osteoporosis group (30 subjects). Then the 68 subjects were further scanned by 1H-MRS and in-phase and out-of-phase MRI and the findings from the imaging methods were also compared and analyzed. It was found that the measured signal intensity ratio(SIR), lipid-wat...

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X-ray CT geometrical calibration via locally linear embedding.

Fri, 25 Mar 2016 17:39:04 +0100

Authors: Chen M, Xi Y, Cong W, Liu B, Wei B, Wang G Abstract For X-ray computed tomography (CT), geometric calibration and rigid patient motion compensation are inter-related issues for optimization of image reconstruction quality. Non-calibrated system geometry and patient movement during a CT scan will result in streak-like, blurring and other artifacts in reconstructed images. In this paper, we propose a locally linear embedding approach to address this challenge under a rigid 2D object assumption and a more general way than what has been reported before. In this method, projections are linearly represented by up-sampled neighbors via locally linear embedding, and CT system parameters are iteratively estimated from projection data themselves. Numerical and experimental studies s...



Ordered-subset Split-Bregman algorithm for interior tomography.

Fri, 25 Mar 2016 17:39:04 +0100

Authors: Kong H, Liu R, Yu H Abstract Inspired by the Compressed Sensing (CS) theory, it has been proved that the interior problem of computed tomography (CT) can be accurately and stably solved if a region-of-interest (ROI) is piecewise constant or polynomial, resulting in the CS-based interior tomography. The key is to minimize the total variation (TV) of the ROI under the constraint of the truncated projections. Coincidentally, the Split-Bregman (SB) method has attracted a major attention to solve the TV minimization problem for CT image reconstruction. In this paper, we apply the SB approach to reconstruct an ROI for the CS-based interior tomography assuming a piecewise constant imaging model. Furthermore, the ordered subsets (OS) technique is used to accelerate the convergence...



Temporal sparsity exploiting nonlocal regularization for 4D computed tomography reconstruction.

Fri, 25 Mar 2016 17:39:04 +0100

Authors: Kazantsev D, Guo E, Kaestner A, Lionheart WR, Bent J, Withers PJ, Lee PD Abstract X-ray imaging applications in medical and material sciences are frequently limited by the number of tomographic projections collected. The inversion of the limited projection data is an ill-posed problem and needs regularization. Traditional spatial regularization is not well adapted to the dynamic nature of time-lapse tomography since it discards the redundancy of the temporal information. In this paper, we propose a novel iterative reconstruction algorithm with a nonlocal regularization term to account for time-evolving datasets. The aim of the proposed nonlocal penalty is to collect the maximum relevant information in the spatial and temporal domains. With the proposed sparsity seeking app...



Monte-Carlo simulation of a slot-scanning digital mammography systemfor tomosynthesis.

Fri, 25 Mar 2016 17:39:04 +0100

CONCLUSIONS: The simulation tool is suitable for slot-scanning FFDM and DBT and may be used for the design and comparison of mammography systems. PMID: 27002901 [PubMed - as supplied by publisher] (Source: Journal of X-Ray Science and Technology)



Photon source term after single collision in targets of silicon, copper and lead for 50-500 keV X-ray beams.

Fri, 25 Mar 2016 17:39:04 +0100

Authors: Nariyama N Abstract Single-scattered X-ray doses at 1 m from silicon, copper and lead targets were calculated using an analytical point-kernel method considering the self-absorption, and the calculated values were compared with detailed results of a Monte Carlo calculation with respect to the emission angle. In the calculations, a slab slanted at 3° to the beam axis was used for silicon in addition to the cylindrical targets for the three materials, and the slab geometry showed the largest doses. The analytical calculations were underestimated compared with the Monte Carlo calculations by less than 24% for silicon and 40% for copper, particularly at large-angle scattering, which was attributable to the buildup effect of the single-scattered X-rays in the targets. By con...



PET/CT links stress with heart trouble

Fri, 25 Mar 2016 17:17:51 +0100

Using PET/CT, researchers have linked a higher radiopharmaceutical activity...Read more on AuntMinnie.comRelated Reading: PET/CT could predict cardiac sarcoidosis outcomes The big question: CT, MRI, or nuclear for coronary artery disease diagnosis? Hybrid imaging gathers momentum in cardiac indications Study shows feasibility of cardiac PET/MRI -- with caveats (Source: AuntMinnie.com Headlines)



Incidental Thyroid Nodules in Non-FDG PETIncidental Thyroid Nodules in Non-FDG PET

Fri, 25 Mar 2016 16:20:18 +0100

A recent retrospective analysis of non-FDG PET nuclear medicine studies shows that although incidental focal thyroid findings are few, they come with a fairly high rate of malignancy. Medscape Radiology (Source: Medscape Today Headlines)



Fostering a Culture of Respect

Fri, 25 Mar 2016 14:35:02 +0100

When you are content to be simply yourself and don’t compare or compete, everybody will respect you.—Lao Szu (Source: Current Problems in Diagnostic Radiology)



Second Malignancies After Radiotherapy for Prostate CancerSecond Malignancies After Radiotherapy for Prostate Cancer

Fri, 25 Mar 2016 14:34:21 +0100

Might irradiation of the prostate contribute to secondary cancers of other organs, such as bladder, colon, lung, and rectum? British Medical Journal (Source: Medscape Radiology Headlines)



Chronic pancreatitis: Bently says he’s ‘ready for a new belly’

Fri, 25 Mar 2016 12:28:24 +0100

  Bently Barnes (center) with Dr. Victor Fox and Dr. Amit Grover, co-directors of the Pancreatic Disorders Program Four-year-old Bently Barnes needed to get ready. He opened the closet door, reached for his camouflage backpack, then scanned his bedroom for the essentials. He grabbed his favorite stuffed animal named, “Marshall,” a truck, tractor and his most prized possession – his blanket. He placed them in his backpack with care, zipped the travel bag and placed it next to his bed. Bently told his mom he was packed and ready to travel from their home in North Carolina to Boston Children’s Hospital. And he was “ready for a new belly,” he said. Early signs of chronic pancreatitis Bently’s mom, Nicole Barnes says her son’s stomach pain began well before his 2...



Reversible mycordial perfusion defects in patients not suffering from obstructive epicardial coronary artery disease as assessed by coronary angiography: a review of the literature.

Fri, 25 Mar 2016 10:50:01 +0100

Authors: VAN DE Wiele C, Rimbu A, Belhocine T, DE Spiegeleer B, Sathekge M, Maes A Abstract In approximately 10-30% of patients presenting with angina complaints, normal or non- obstructive coronary arteries are found on angiography. In this review paper, available literature on the underlying pathophysiological substrate explaining these discrepancies is reviewed. Both histological studies as well as studies using intravascular ultrasound e.g. the PROSPECT trial, show that epicardial coronary vessel significant lumen stenosis may be delayed until a plaque occupies 40% of the internal elastic lamina area. Limited available data suggest that these angiographically undetectable plaques are associated with an abnormal vasodilation capacity of the coronary circulation and may results i...



The proposed physiology-based FDG PET/CT criteria in reducing false-positive results in advanced head and neck cancer after chemoradiotherapy.

Fri, 25 Mar 2016 10:50:01 +0100

CONCLUSION: By incorporating physiological changes following CCRT, our visual rating criteria improved the accuracy of the currently used FDG PET/CT visual rating system, especially the number of false-positive cases with advanced HNSCC after CCRT. PMID: 27007664 [PubMed - as supplied by publisher] (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)

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Interventional technologists have higher cancer risk

Fri, 25 Mar 2016 07:00:00 +0100

Radiologic technologists who perform fluoroscopically guided interventional...Read more on AuntMinnie.comRelated Reading: Interventional radiology needs accurate dose tracking Interventional radiology sees many code changes in 2016 Interventional radiologists need to follow shielding protocols Cardiac cath delivers high radiation doses to operators Protective device makes interventional procedures safer for radiologists (Source: AuntMinnie.com Headlines)



Varian opens office in Algeria

Fri, 25 Mar 2016 07:00:00 +0100

Radiation therapy firm Varian Medical Systems has expanded its operations in...Read more on AuntMinnie.comRelated Reading: Varian launches new Beacon transponder Varian preps new products for ECR 2016 Varian posts mixed Q1 results Varian gets Saudi OK for proton therapy system Varian sees slight revenue increase in 2015 (Source: AuntMinnie.com Headlines)



CDC: Progress stalls in tuberculosis fight

Fri, 25 Mar 2016 07:00:00 +0100

The annual incidence of tuberculosis has leveled off in the U.S., arresting...Read more on AuntMinnie.comRelated Reading: TB screening may not be needed for Canadian immigrants Technique boosts x-ray CAD results for TB PET/CT identifies tuberculosis drug efficacy Chest x-ray still has value for tuberculosis screening Russia pursues reform of TB screening system (Source: AuntMinnie.com Headlines)



Global ultrasound market will top $6.8B by 2020

Fri, 25 Mar 2016 07:00:00 +0100

The worldwide ultrasound market will reach $6.86 billion by 2020, according...Read more on AuntMinnie.comRelated Reading: Report pegs digital x-ray market to reach $10.5B by 2020 Report: Healthcare 3D printing market ready to explode Breast cancer diagnostic devices sector set for growth Electronic health records market to reach $24B by 2020 Global digital x-ray market could reach $8.7B (Source: AuntMinnie.com Headlines)

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NIST publishes breast MRI standards

Fri, 25 Mar 2016 07:00:00 +0100

The U.S. National Institute of Standards and Technology (NIST) has released...Read more on AuntMinnie.comRelated Reading: Video from ECR 2016: Dr. Christiane Kuhl on breast MRI Short is just as sweet for breast MRI protocol Breast imaging method yields quantitative analysis Clinical audit sheds light on breast MRI performance NIST requests EHRs to evaluate usability (Source: AuntMinnie.com Headlines)



Study uses US to investigate pregnancy complications

Fri, 25 Mar 2016 07:00:00 +0100

Researchers from Virginia and Texas have received a grant for $2.7 million...Read more on AuntMinnie.comRelated Reading: Toshiba completes $6B deal to sell medical unit to Canon Reuters: Fuji questions Toshiba's Canon pick Toshiba taps Canon as exclusive suitor for medical division Report: Toshiba to make medical unit decision this week New angio x-ray unit paces Toshiba's ECR 2016 product launches (Source: AuntMinnie.com Headlines)



Mammography could help screen for heart disease

Fri, 25 Mar 2016 07:00:00 +0100

Routine mammography screening could be a useful tool for identifying women...Read more on AuntMinnie.comRelated Reading: Automated CAC fares well in CT lung screening scans Coronary CTA yields prognostic boost over CAC Study on CT calcium testing redefines who needs statins US spots subclinical atherosclerosis in low-risk women NIH study ties soft plaque on CT to cardiac risk factors (Source: AuntMinnie.com Headlines)



Mammograms May Also Help Spot Heart Disease, Study Suggests

Thu, 24 Mar 2016 23:00:00 +0100

The breast screening test compared well to heart CT scans, researchers say (Source: The Doctors Lounge - Oncology)



Connectivity-based parcellation increases network detection sensitivity in resting state fMRI: An investigation into the cingulate cortex in autism

Thu, 24 Mar 2016 23:00:00 +0100

Publication date: Available online 25 March 2016 Source:NeuroImage: Clinical Author(s): Joshua H. Balsters, Dante Mantini, Matthew A.J. Apps, Simon B. Eickhoff, Nicole Wenderoth Although resting state fMRI (RS-fMRI) is increasingly used to generate biomarkers of psychiatric illnesses, analytical choices such as seed size and placement can lead to variable findings. Seed placement especially impacts on RS-fMRI studies of Autism Spectrum Disorder (ASD), because individuals with ASD are known to possess more variable network topographies. Here, we present a novel pipeline for analysing RS-fMRI in ASD using the cingulate cortex as an exemplar anatomical region of interest. Rather than using seeds based on previous literature, or gross morphology, we used a combination of structural info...

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Reliability of the modified Tufts Lumbar Degenerative Disc Classification between neurosurgeons and neuroradiologists

Thu, 24 Mar 2016 23:00:00 +0100

Publication date: Available online 25 March 2016 Source:Journal of Clinical Neuroscience Author(s): Shane M. Burke, Steven W. Hwang, William A. Mehan, Harprit S. Bedi, Richard Ogbuji, Ron I. Riesenburger Cross-specialty inter-rater reliability has not been explicitly reported for imaging characteristics that are thought to be important in lumbar intervertebral disc degeneration. Sufficient cross-specialty reliability is an essential consideration if radiographic stratification of symptomatic patients to specific treatment modalities is to ever be realized. Therefore the purpose of this study was to directly compare the assessment of such characteristics between neurosurgeons and neuroradiologists. Sixty consecutive patients with a diagnosis of lumbago and appropriate imaging were s...



A parameterized logarithmic image processing method with Laplacian of Gaussian filtering for lung nodule enhancement in chest radiographs

Thu, 24 Mar 2016 23:00:00 +0100

Abstract The enhancement of lung nodules in chest radiographs (CXRs) plays an important role in the manual as well as computer-aided detection (CADe) lung cancer. In this paper, we proposed a parameterized logarithmic image processing (PLIP) method combined with the Laplacian of a Gaussian (LoG) filter to enhance lung nodules in CXRs. We first applied several LoG filters with varying parameters to an original CXR to enhance the nodule-like structures as well as the edges in the image. We then applied the PLIP model, which can enhance lung nodule images with high contrast and was beneficial in extracting effective features for nodule detection in the CADe scheme. Our method combined the advantages of both the PLIP algorithm and the LoG algorithm, which can enhance lung nodules in c...



Non-neoplastic variants of the sternum detected on bone scintigraphy using a hybrid SPECT/CT machine

Thu, 24 Mar 2016 23:00:00 +0100

Conclusion Increased sternal uptake is significantly associated with CT structural abnormalities and knowledge of these non-neoplastic variants is essential for correct interpretation of SPECT/CT bone scans especially in patients with known cancers. (Source: The Egyptian Journal of Radiology and Nuclear Medicine)



CT negative attenuation pixel distribution and texture analysis for detection of fat in small angiomyolipoma on unenhanced CT

Thu, 24 Mar 2016 23:00:00 +0100

Conclusion CT negative attenuation pixel distribution analysis does not identify fat in AML beyond subjective evaluation. Addition of skewness by texture analysis may help improve identifying fat in AML. (Source: Abdominal Imaging)

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Imaging patients with renal impairment

Thu, 24 Mar 2016 23:00:00 +0100

Abstract Imaging with intravascular contrast media is generally considered safe, particularly in patients without renal failure. However, as renal function deteriorates, the potential risk of nonallergic-type adverse events increases. This presents a unique challenge, particularly when the use of intravenous contrast media is deemed essential for diagnostic purposes. Following a discussion regarding the definition and epidemiology of kidney injury, this review focuses on the evolving understanding of both contrast-induced nephropathy and nephrogenic systemic fibrosis and discusses preventative strategies aimed at minimizing the risk of developing these entities. Alternative non-contrast imaging techniques are also discussed. (Source: Abdominal Imaging)



Fatal pleural mesothelioma in Japan (2003–2008): evaluation of computed tomography findings

Thu, 24 Mar 2016 23:00:00 +0100

Conclusions Upon examination of the CT scans at diagnosis, 18 % of mesothelioma cases did not show a clear irregularity. When diagnosing pleural effusion of unknown etiology, it is necessary to consider the possibility of mesothelioma even when no plaque and pleural irregularity are observed. (Source: Japanese Journal of Radiology)



Abdominal fat distribution and carotid atherosclerosis in a general population: a semi-automated method using magnetic resonance imaging

Thu, 24 Mar 2016 23:00:00 +0100

Conclusions A higher amount of visceral fat, measured by a semi-automated technique using MRI, is associated with increased IMT and having more than one carotid plaque in a general population, while subcutaneous fat measures are poor indicators for identifying carotid atherosclerosis. (Source: Japanese Journal of Radiology)



Integrating health education and physical activity programming for cardiovascular health promotion among female inmates: A proof of concept study

Thu, 24 Mar 2016 23:00:00 +0100

This study will test proof of concept, feasibility, and potential efficacy of a multiple health behavior change intervention that integrates CV-health promotion education delivered during a physical activity (PA) program (indoor cycling) tailored to this population. (Source: Contemporary Clinical Trials)



Results of a National Radiology Attending Physician Survey: The Effects of In-House Late and Overnight Attending Coverage on Radiology Resident Training

Thu, 24 Mar 2016 23:00:00 +0100

Over the past 10 years, there has been increased attending-level image interpretation during what has typically been considered the on-call period. The purpose of this study is to survey radiology attending physicians and assess their perceptions about how the presence of radiology attending physicians during the on-call period affects patient care and resident education. Two hundred eighty-eight radiology attendings completed the online survey. 70% believe that after hours final reads by radiology attendings improves patient care. (Source: Current Problems in Diagnostic Radiology)



Characterization of Adrenal Adenoma by Gaussian Model-Based Algorithm

Thu, 24 Mar 2016 23:00:00 +0100

We confirmed that computed tomography (CT) attenuation values of pixels in an adrenal nodule approximate a Gaussian distribution. Building on this and the previously described histogram analysis method, we created an algorithm that uses mean and standard deviation to estimate the percentage of negative attenuation pixels in an adrenal nodule, thereby allowing differentiation of adenomas and nonadenomas. The institutional review board approved both components of this study in which we developed and then validated our criteria. (Source: Current Problems in Diagnostic Radiology)



Disappearing Acts: The Many Causes of Rapidly Destructive Arthritis

Thu, 24 Mar 2016 23:00:00 +0100

We describe both the common and less common etiologies of rapidly destructive arthropathy that one should consider, with imaging examples, and present discriminative factors when present. (Source: Current Problems in Diagnostic Radiology)



Rating and Classification of Incident Reporting in Radiology in a Large Academic Medical Center

Thu, 24 Mar 2016 23:00:00 +0100

The purpose of this article is to provide a rate of safety incident report of adverse events in a large academic radiology department and to share the various types that may occur. This is a Health Insurance Portability and Accountability Act compliant, institutional review board–approved study. Consent requirement was waived. All incident reports from April 2006-September 2012 were retrieved. Events were further classified as follows: diagnostic test orders, identity document or documentation or consent, safety or security or conduct, service coordination, surgery or procedure, line or tube, fall, medication or intravenous safety, employee general incident, environment or equipment, adverse drug reaction (ADR), skin or tissue, and diagnosis or treatment. (Source: Current Problems in Dia...



Cost-Savings Analysis of Renal Scintigraphy, Stratified by Renal Function Thresholds: Mercaptoacetyltriglycine Versus Diethylene Triamine Penta-Acetic Acid

Thu, 24 Mar 2016 23:00:00 +0100

To determine the financial implications of switching technetium (Tc)-99m mercaptoacetyltriglycine (MAG-3) to Tc-99m diethylene triamine penta-acetic acid (DTPA) at certain renal function thresholds before renal scintigraphy. (Source: Journal of the American College of Radiology : JACR)

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Prostate Embolization as an Alternative to Open Surgery in Patients with Large Prostate and Moderate to Severe Lower Urinary Tract Symptoms

Thu, 24 Mar 2016 23:00:00 +0100

To evaluate efficacy of prostate artery embolization (PAE) in patients with benign prostatic hyperplasia (BPH), prostate volume (PV) > 100 cm3. (Source: Journal of Vascular and Interventional Radiology : JVIR)



Correlation between the severity of cetuximab-induced skin rash and clinical outcome for head and neck cancer patients: The XXXX experience

Thu, 24 Mar 2016 23:00:00 +0100

Present study evaluated the severity of cetuximab-induced skin rash and its correlation with clinical outcome and late skin toxicity in patients HNSCC treated with chemoradiotherapy and cetuximab in two prospective randomized trials. Grade 2-4 cetuximab rash was associated with better survival possibly due to reduction of distant metastasis. This observation was noted mainly in p16 negative patients. Grade 2-4 acute in-field radiation dermatitis was associated with higher rate of late Grade 2-4 skin fibrosis. (Source: International Journal of Radiation Oncology * Biology * Physics)



Personalized Management Approaches in Lymphoma

Thu, 24 Mar 2016 23:00:00 +0100

This article summarizes the most up-to-date literature surrounding the topic of PET/CT-adaptive treatment of different lymphoma subjects. Although more studies are necessary to solidify the role of PET/CT, it is clear that this imaging modality holds much promise for the development of response-adaptive treatment algorithms in the future. (Source: PET Clinics)

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Dependence of treatment planning accuracy in peptide receptor radionuclide therapy on the sampling schedule

Thu, 24 Mar 2016 23:00:00 +0100

Conclusions When using a priori information of a PBPK model structure combined with Bayesian information about PBPK model parameter distribution, the administered activity could be determined with acceptable accuracy using only two time points (4 h, 2 d) and thus allow a considerable reduction of needed data for individual dosimetry. (Source: EJNMMI Research)



Intramuscular migration of calcific tendinopathy in the rotator cuff: ultrasound appearance and a review of the literature

Thu, 24 Mar 2016 23:00:00 +0100

We present four cases of an even more rare condition, not well described in literature yet, the intramuscular migration of calcium. (Source: Journal of Ultrasound)



Cost-Savings Analysis of Renal Scintigraphy, Stratified by Renal Function Thresholds: Mercaptoacetyltriglycine Versus Diethylene Triamine Penta-Acetic Acid

Thu, 24 Mar 2016 23:00:00 +0100

Conclusions Reserving MAG-3 utilization for patients who have impaired renal function can impart substantial annual cost savings to a radiology department. (Source: Journal of the American College of Radiology)