Last Build Date: Tue, 24 Jan 2017 17:14:50 +0000
Tue, 24 Jan 2017 02:00:00 +0000Professor Li-Huei Tsai Professor and Director - Picower Institute for Learning and Memory Department of Brain and Cognitive Sciences, Massachusetts Avenue, Cambridge MA 02139, USA Title: Using patterned neural activity to modify Alzheimers disease pathology
Mon, 30 Jan 2017 02:00:00 +0000Dr Jai Yu Howard Hughes Medical Institute, Department of Physiology, University of California, San Francisco, USA Title: Encoding and storing experience in hippocampal-cortical networks Abstract: While ongoing experience proceeds continuously, memories of past experience are often recalled as episodes with defined beginnings and ends. The neural mechanisms that transform the stream of neural activity patterns representing ongoing experience into discrete episodes are unknown. To investigate these mechanisms, we recorded neural activity in the hippocampus and prefrontal cortex, both of which are critical for memory processes. We show that during spatial navigation, hippocampal CA1 place cells maintain a continuous spatial representation across different states of motion (movement and immobility). In contrast, during sharp-wave ripples, when stored representations of experience are transiently expressed, movement and immobility-associated activity patterns are most often reactivated separately. Moreover, hippocampal reactivations of movement or immobility experiences are accompanied by distinct patterns of modulation in prefrontal cortex. These findings demonstrate a continuous representation of experience can be separated into independently reactivated memory representations across the hippocampal-cortical network.
Mon, 30 Jan 2017 02:00:00 +0000Dr. Ramkumar Menon, Associate Professor of Obstetrics and Gynecology, The University of Texas Medical Branch (UTMB) at Galveston, Texas, USA, has been working in the area of Perinatal Biology and Reproductive Immunology for the past 25 years to understand the pathways and mechanisms of spontaneous preterm birth (PTB) and preterm prelabor rupture of the membranes (pPROM). Earlier in his career, Dr. Menon, developed an in vitro organ explant system to determine the response of human fetal membranes in response to various risk factors of PTB and pPROM. This model and its variations are now widely used to understand fetal immune and endocrine responses by many investigators around the globe.upture of the membranes (pPROM). His work highlights how aging of fetal membranes generate specific signals and how they are propagated between feto-maternal tissues via exosomes. This novel signaling mechanism by exosomes is expected to contribute immensely to our understanding of parturition process at term and preterm.
Tue, 31 Jan 2017 02:00:00 +0000Dr Zhaoyu Li Research Investigator, Life Sciences Institute, University of Michigan, Ann Arbor, USA Title: Synaptic and circuit mechanisms of sensorimotor integration in C. elegans Abstract: How the nervous system encodes behaviors is a central question in neuroscience. Despite the incredible repertoire of activities performed by the brain, the fundamental units are synaptic connections between neurons in circuits. However, due to the huge numbers of neurons and synapses in the brain (e.g., ~100 billion neurons and ~100 trillion synapses in the human brain), it is a considerable challenge to elucidate the specific mechanisms by which neural circuits process sensory information to generate motor output. As the only multicellular organism with a completely mapped connectome, C. elegans provides the ideal platform to study basic principles underlying neural network computation and sensorimotor integration. By employing multidisciplinary approaches, including targeted optogenetics, in vivo calcium imaging, quantitative behavioral analysis, molecular genetics and behavioral genetics, I identified distinct circuit motifs involved in sensorimotor integration. I found one first layer interneuron that is primarily downstream of chemosensory neurons, recruits a divergent circuit to encode multiple motor outputs. In addition, I found multiple interneurons coordinate to fine tune a motor circuit activity and encode an adaptive motor behavior. My research elucidates the synaptic and circuit mechanisms of how the nervous system processes sensorimotor information and highlights how the model organism C. elegans can be used to answer fundamental questions in neuroscience.
Tue, 14 Feb 2017 02:00:00 +0000Dr Brown received his PhD from QUT studying under Professor Lavin at QIMR and subsequently moved to Galway, Ireland. He has worked in the Centre for Chromosome Biology, the Regenerative Medicine Institute/Systems Biology Ireland and is currently an Honorary Research Lecturer and Junior Group Leader (mentored by Professor Michael Kerin) at the Lambe Institute of Translational Research (School of Medicine National University of Ireland Galway). He has a strong research record and was awarded the prestigious European Association for Cancer Research young scientist award (2015) by the Irish association for Cancer Research (IACR) for his publication in Scientific Reports (Gao et al, 2014) developing and validating a novel compound that preferentially targets breast cancer. His group is currently focused on discovering and evaluating breast cancer biomarkers (microRNA or protein) found in circulation or in primary tumours.
Thu, 23 Feb 2017 08:00:00 +0000Australias ageing population presents major challenges to the health sector however it is not the main source of health expenditure growth. An increase in technological innovation is a driving force behind rising health care costs and together with income growth, population age and the widespread availability of insurance, Australia faces a major expenditure challenge. The Australian Treasury estimates that in the absence of disruption to current trends, health expenditure will increase from its current levelwhich is just over 9% of Gross Domestic Product (GDP)to more than 27% of GDP by 2050. This Global Leadership Series event will explore the opportunities and challenges faced by the Australian health sector and provide suggested solutions to enable Australia to innovate in the prevention and treatment of illness, while containing costs.
Sat, 05 Aug 2017 23:00:00 +0000Learning how to plan a successful QTAC application, hearing about scholarships and exchange opportunities and getting tips from current university students are all options for anyone attending the UQ St Lucia Open Day. Visitors to Open Day can explore the St Lucia campus, check out the world-class facilities, learn more about the unique courses and career options at the UQ Centre information hub, meet inspiring teachers and staff and experience the vibrant campus lifestyle.
Sun, 20 Aug 2017 23:00:00 +0000Sustainability Week is an opportunity for the UQ community to promote and celebrate sustainability across UQ`s campuses and sites. Throughout the week a range of activities and events are hosted across all areas of the University. The program typically includes: - specialist presentations and workshops - tree plantings, bird watching and garden tours - PV solar talks and site tours - forums and panel discussions - film screenings - competitions and challenges to inspire sustainable behaviours
Tue, 12 Sep 2017 14:00:00 +0000The UQ Advantage Office is proud to host the annual UQ Undergraduate Research Conference during UQ`s Research Week. The event showcases some of UQs finest undergraduate research projects through oral, poster and elevator pitch presentations. The university wide conference is a great way for students to develop their communication skills, meet other students, and present their research project to the wider UQ community. Students are asked to apply online to present at the conference. All students, staff, alumni and friends are welcome to attend to watch the presentations.
Wed, 20 Sep 2017 06:00:00 +0000Have your coursework and research questions answered, at UQ`s Postgraduate Advice Night. Discuss your study options, attend seminars, explore the campus and find out how UQ`s world-class postgraduate qualifications can help advance your career.
Mon, 30 Oct 2017 14:00:00 +0000Teaching and Learning Week is an opportunity for the UQ community to celebrate and share innovative and excellent teaching and learning practices that engage and inspire students. The program is designed to provide staff with opportunities to network and discuss teaching and learning in contemporary contexts, and how this impacts on the student experience and outcomes.