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MedWorm: Nutrition provides a medical RSS filtering service. Over 7000 RSS medical sources are combined and output via different filters. This feed contains the latest news and research in Nutrition

Last Build Date: Sun, 27 Mar 2016 23:34:56 +0100


Saturated and Unsaturated Dietary Fats Differentially Modulate Ethanol-Induced Changes in Gut Microbiome and Metabolome in a Mouse Model of Alcoholic Liver Disease.

Sun, 27 Mar 2016 18:55:02 +0100

Authors: Kirpich IA, Petrosino J, Ajami N, Feng W, Wang Y, Liu Y, Beier JI, Barve SS, Yin X, Wei X, Zhang X, McClain CJ Abstract Alcoholic liver disease (ALD) ranks among major causes of morbidity and mortality. Diet and crosstalk between the gut and liver are important determinants of ALD. We evaluated the effects of different types of dietary fat and ethanol on the gut microbiota composition and metabolic activity and the effect of these changes on liver injury in ALD. Compared with ethanol and a saturated fat diet (medium chain triglycerides enriched), an unsaturated fat diet (corn oil enriched) exacerbated ethanol-induced endotoxemia, liver steatosis, and injury. Major alterations in gut microbiota, including a reduction in Bacteroidetes and an increase in Proteobacteria and Ac...

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Assessment of Aortic Elasticity in Patients with Celiac Disease.

Sun, 27 Mar 2016 13:03:02 +0100

CONCLUSION: Patients with CD had increased aortic stiffness and decreased aortic distensibility. Gluten-free diet enabled the patients with CD to have a reduction in the inflammatory parameters whereas the absence of a significant difference in the elastic properties of the aorta may suggest that the risk of cardiovascular disease persists in this patient group despite a gluten-free diet. PMID: 27014355 [PubMed] (Source: Korean Circulation Journal)

Eosinophilic Esophagitis: An Evidence-Based Approach to Therapy.

Sun, 27 Mar 2016 09:51:02 +0100

Authors: González-Cervera J, Lucendo AJ Abstract In recent years, several randomized controlled trials and meta-analyses have evaluated the efficacy of the various therapeutic options available for treating patients with eosinophilic esophagitis, including dietary modifications, proton pump inhibitors, topical corticosteroids, and endoscopic esophageal dilation. Proton pump inhibitors are currently considered the first-line treatment for eosinophilic esophagitis, achieving histological remission and improvement of symptoms in 50.5% and 60.8% of patients, respectively. The efficacy of topical corticosteroids in eosinophilic esophagitis has been assessed in several trials. Meta-analyses summarizing results indicate that budesonide and fluticasone propionate are significantly superio...

The Reasearch on the Anti-Fatigue Effect of Whey Protein Powder in Basketball Training.

Sun, 27 Mar 2016 08:04:02 +0100

Authors: Ronghui S Abstract In order to observe the effects of whey protein powder on hematological indexes of players majoring in physical education in the basketball training, the authors divided the players randomly into a control group and a nutrition group. Athletes complete the 30 minutes quantitative exercise using cycle ergometer respectively before the trial and after one month trial. Then we exsanguinated immediately after exercise, extracted heparin and measured hemoglobin, red blood cell count, hematocrit and mean corpuscular volume and other hematological indices. The results showed that after taking whey protein powder, the HB, RBC, HCT of nutrition group was significantly higher that the control group. This suggests that in high-intensity training, taking whey protei...

Research on Effects and Compatibility Taking of Different Sports Supplements on the Biochemical Indicators and Body Functions of Elite Walking Athletes.

Sun, 27 Mar 2016 08:04:02 +0100

Authors: Jia J Abstract Scientific training, elimination of fatigue, and reasonable nutrition is the three important parts of successful training. Especially in the fatigue recovery and reasonable nutrition of track and field endurance project, which is more important than other project significance? This paper is to more scientific nutritional intervention on the walking athletes to improve athletic performance and provide experimental evidence 12 male and 12 female athletes were selected from the Chinese national walking team were given the nutrition intervention of a variety of sports supplements for 9 weeks. The serum testosterone (T), blood urea (BU), and serum creative phosphokinase (CK) and other indicators were tested in several weekends. The results showed that the differe...

The Research on the Effect of the Food with Different Glycaemic Index and Glycaemic Load on the Immunity of Endurance Athletes.

Sun, 27 Mar 2016 08:04:02 +0100

Authors: Li D Abstract For studying the effect of eating the food containing carbohydrates with different glycaemic index and glycaemic load 2 hours before athletics on the exercise tolerance and immune function, select 10 men long-distance endurance athletes, use not completely random balance repeated testing methods, randomized complete the three endurance tests. And each test interval is not less than seven days. The results suggest that there is no apparent effect of eating the food containing carbohydrates with different glycaemic index and glycaemic load 2 hours before athletics on the exercise tolerance and immune function. Compared with the glycaemic index and glycaemic load of food, the carbohydrate content of the diet before athletics may be the more important factor affe...

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Sun, 27 Mar 2016 07:01:02 +0100

Authors: Abstract [This corrects the article DOI: 10.3164/jcbn.13-107.]. PMID: 27013785 [PubMed] (Source: Journal of Clinical Biochemistry and Nutrition)

Disorder of autonomic nervous system and its vulnerability to external stimulation in functional dyspepsia.

Sun, 27 Mar 2016 07:01:02 +0100

Authors: Tominaga K, Fujikawa Y, Tsumoto C, Kadouchi K, Tanaka F, Kamata N, Yamagami H, Tanigawa T, Watanabe T, Fujiwara Y, Arakawa T Abstract To elucidate the role of autonomic nervous system in functional dyspepsia patients, we examined 24-h heart rate variability: the basal levels, responses after lunch, cold pressor and mental arithmetic tests, and the efficacy of an autonomic drug (tofisopam). The high-frequency component (HF: 0.15-0.40 Hz) and the ratio of HF to the low-frequency component (LF: 0.04-0.15 Hz; LF/HF ratio) were used as indicators of parasympathetic and sympathetic autonomic nervous system function. The HF component in the 24-h, daytime, and nighttime was low in 86.7%, 97.8%, and 66.7% of patients (n = 45) and the LF/HF ratio was high in 51.1%, 73.3%, and 26...

Pain-reducing anesthesia prevents oxidative stress in human term placenta.

Sun, 27 Mar 2016 07:01:02 +0100

In this study, we immunohistochemically analyzed two markers for oxidative stress, namely 8-hydroxy-2'-deoxyguanosine (8-OHdG) and 4-hydroxy-2-nonenal-modified proteins (HNE), using placentas from 21 cases of normal tansvaginal delivery (V group), 20 Caesarean sections (C group), and 17 normal transvaginal deliveries with epidural anesthesia (E group). 8-OHdG staining in the nuclei of trophoblasts lining the chorionic villi was significantly stronger in the V group either compared with the C or E group (p<0.001), without significant differences in the C and E groups (p = 0.792). Moderate to intense staining by HNE of the intravascular serum of chorionic villi vasculature was frequently observed in the placentas from the V group, but less frequently of those in either C or E groups (p&...

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Chlorogenic acid from honeysuckle improves hepatic lipid dysregulation and modulates hepatic fatty acid composition in rats with chronic endotoxin infusion.

Sun, 27 Mar 2016 07:01:02 +0100

In this study, we investigated the effect of chlorogenic acid in rats with chronic endotoxin infusion. The Sprague-Dawley rats with lipid metabolic disorder (LD group) were intraperitoneally injected endotoxin. And the rats of chlorogenic acid-LD group were daily received chlorogenic acid by intragastric administration. In chlorogenic acid-LD group, the area of visceral adipocyte was decreased and liver injury was ameliorated, as compared to LD group. In chlorogenic acid-LD group, serum triglycerides, free fatty acids, hepatic triglycerides and cholesterol were decreased, the proportion of C20:1, C24:1 and C18:3n-6, Δ9-18 and Δ6-desaturase activity index in the liver were decreased, and the proportion of C18:3n-3 acid was increased, compared to the LD group. Moreover, levels of phosphory...

Combined effects of soy isoflavones and milk basic protein on bone mineral density in hind-limb unloaded mice.

Sun, 27 Mar 2016 07:01:02 +0100

We examined whether the combination of isoflavone and milk basic protein both are reported to be effective for bone metabolism, prevents bone loss induced by skeletal hind-limb unloading in mice. Female ddY strain mice, aged 8 weeks, were divided into six groups (n = 6-8 each): (1) normally housed group, (2) loading group, (3) hind-limb unloading group fed a control diet, (4) hind-limb unloading group fed a 0.2% isoflavone conjugates diet, (5) hind-limb unloading group fed a 1.0% milk basic protein diet, and (6) hind-limb unloading group fed a 0.2% isoflavone conjugates and 1.0% milk basic protein diet. After 3 weeks, femoral bone mineral density was markedly reduced in unloading mice. The combination of isoflavone and milk basic protein showed cooperative effects in preventing bone loss...

Non-invasive measurement of skin autofluorescence to evaluate diabetic complications.

Sun, 27 Mar 2016 07:01:02 +0100

This study provides the first evidence that the accumulation of fluorophore in the fingertip increases with an increasing number of microvascular complications, demonstrating that the presence of diabetic microvascular complications may be predicted by measuring the fluorophore concentration in the fingertip. PMID: 27013780 [PubMed] (Source: Journal of Clinical Biochemistry and Nutrition)

Soft-shelled turtle eggs inhibit the formation of AGEs in the serum and skin of diabetic rats.

Sun, 27 Mar 2016 07:01:02 +0100

This report provides the first evidence that the oral administration of STE reduces the formation of AGEs, suggesting that one of the health effects of STE may be the inhibition of AGEs formation. PMID: 27013779 [PubMed] (Source: Journal of Clinical Biochemistry and Nutrition)

Dietary zinc deficiency induces oxidative stress and promotes tumor necrosis factor-α- and interleukin-1β-induced RANKL expression in rat bone.

Sun, 27 Mar 2016 07:01:02 +0100

Authors: Suzuki T, Katsumata S, Matsuzaki H, Suzuki K Abstract We investigated the effects of dietary zinc deficiency on oxidative stress and bone metabolism. Four-week-old male Wistar rats were randomly assigned to one of three groups for 4 weeks: a zinc-adequate group (30 ppm); a zinc-deficient group (1 ppm); and a pair-fed group (30 ppm) that was pair-fed to the zinc-deficient group. The iron content and the thiobarbituric acid reactive substance level in bone were higher in the zinc-deficient group than in the zinc-adequate and pair-fed groups. The mRNA expression level of osteoblastogenesis-related genes such as bone morphogenetic protein 2 and runt-related transcription factor 2 was lower in the zinc-deficient group than in the zinc-adequate and pair-fed groups. In contras...

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Tocotrienol improves learning and memory deficit of aged rats.

Sun, 27 Mar 2016 07:01:02 +0100

Authors: Kaneai N, Sumitani K, Fukui K, Koike T, Takatsu H, Urano S Abstract To define whether tocotrienol (T-3) improves cognitive deficit during aging, effect of T-3 on learning and memory functions of aged rats was assessed. It was found that T-3 markedly counteracts the decline in learning and memory function in aged rats. Quantitative analysis of T-3 content in the rat brain showed that the aged rats fed T-3 mixture-supplemented diet revealed the transport of α- and γ-T-3 to the brain. In contrast, normal young rats fed the same diet did not exhibit brain localization. Furthermore, the T-3 inhibited age-related decreases in the expression of certain blood brain barrier (BBB) proteins, including caludin-5, occludin and junctional adhesion molecule (JAM). It was found that the...

Down-regulation of dihydrofolate reductase inhibits the growth of endothelial EA.hy926 cell through induction of G1 cell cycle arrest via up-regulating p53 and p21(waf1/cip1) expression.

Sun, 27 Mar 2016 07:01:02 +0100

Authors: Fei Z, Gao Y, Qiu M, Qi X, Dai Y, Wang S, Quan Z, Liu Y, Ou J Abstract Folic acid supplementation may meliorate cardiovascular disease risk by improving vascular endothelial structure and function. However, the underlying mechanisms are still lack of a global understanding. To be used, folic acid must be converted to 7,8-dihydrofolate by dihydrofolate reductase to generate one-carbon derivatives serving as important cellular cofactors in the synthesis of nucleotides and amino acids required for cell growth. Therefore, this study explored the effect of dihydrofolate reductase knockdown on endothelial EA.hy926 cell growth and the mechanism involved. We found that down-regulation of dihydrofolate reductase inhibited EA.hy926 cell proliferation, and induced G1 phase arrest. Me...

Neutrophil myeloperoxidase and its substrates: formation of specific markers and reactive compounds during inflammation.

Sun, 27 Mar 2016 07:01:02 +0100

Authors: Kato Y Abstract Myeloperoxidase is an inflammatory enzyme that generates reactive hypochlorous acid in the presence of hydrogen peroxide and chloride ion. However, this enzyme also uses bromide ion or thiocyanate as a substrate to form hypobromous or hypothiocyanous acid, respectively. These species play important roles in host defense against the invasion of microorganisms. In contrast, these enzyme products modify biomolecules in hosts during excess inflammation, indicating that the action of myeloperoxidase is both beneficial and harmful. Myeloperoxidase uses other endogenous compounds, such as serotonin, urate, and l-tyrosine, as substrates. This broad-range specificity may have some biological implications. Target molecules of this enzyme and its products vary, includ...

Redox signaling regulated by electrophiles and reactive sulfur species.

Sun, 27 Mar 2016 07:01:02 +0100

Authors: Nishida M, Kumagai Y, Ihara H, Fujii S, Motohashi H, Akaike T Abstract Redox signaling is a key modulator of oxidative stress induced by nonspecific insults of biological molecules generated by reactive oxygen species. Current redox biology is revisiting the traditional concept of oxidative stress, such that toxic effects of reactive oxygen species are protected by diverse antioxidant systems upregulated by oxidative stress responses that are physiologically mediated by redox-dependent cell signaling pathways. Redox signaling is thus precisely regulated by endogenous electrophilic substances that are generated from reactive oxygen species and nitric oxide and its derivative reactive species during stress responses. Among electrophiles formed endogenously, 8-nitroguanosine ...

Seriously, get Splenda OUT of your diet if you haven't done so already

Sun, 27 Mar 2016 06:00:00 +0100

(NaturalNews) It's official: Splenda is definitely bad for you.If you've already begun to avoid most or all processed foods, choose kale instead of cake, and have even flirted with ditching all dairy products, then you're already well on your way to becoming healthier and better... (Source:

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Synchrotron X-ray Fluorescence Microscopy study of the diffusion of iron, manganese, potassium and zinc in parboiled rice kernels

Sat, 26 Mar 2016 23:00:00 +0100

Publication date: September 2016 Source:LWT - Food Science and Technology, Volume 71 Author(s): Prakash Oli, Rachelle Ward, Benu Adhikari, A. John Mawson, Raju Adhikari, Tim Wess, Laura Pallas, Kathryn Spiers, David Paterson, Peter Torley Parboiled rice is known to contain higher levels of nutrients than its non-parboiled counterpart. In order to study the diffusion of micronutrients into the starchy endosperm of the parboiled rice kernel, the parboiled paddy samples were prepared by combining different hydrothermal treatments (hydrated only, steamed-only, hydrated then steamed) employing two hydration temperatures (60 °C and 90 °C). The rice kernels were sectioned longitudinally into 90 μm thick sections after hydrothermal treatment, drying and milling. These rice kernel...

The Role of Vitamin E in Breast Cancer...

Sat, 26 Mar 2016 23:00:00 +0100

Does vitamin E have a role in either the prevention or treatment of breast cancer, and how do dietary sources differ from food sources? (Source: Breast Cancer)

Losing Unwanted Weight During Chemotherapy

Sat, 26 Mar 2016 23:00:00 +0100

Even if you're looking to lose a few pounds, you don't want to begin while on chemotherapy. Your body needs the nutrients to heal and repair damaged tissues. (Source: Colon Cancer)

Antiangiogenic activity of 2-formyl-8-hydroxy-quinolinium chloride

Sat, 26 Mar 2016 23:00:00 +0100

Publication date: May 2016 Source:Biomedicine & Pharmacotherapy, Volume 80 Author(s): K.-H. Lam, K.K.-H. Lee, S.H.-L. Kok, R.S.-M. Wong, F.-Y. Lau, G.Y.-M. Cheng, W.-Y. Wong, S.-W. Tong, K.-W. Chan, R.Y.-K. Chan, J.C.-O. Tang, C.-H. Cheng, D.K.-P. Hau, Z.-X. Bian, R. Gambari, C.-H. Chui Tumour growth is closely related to the development of new blood vessels to supply oxygen and nutrients to cancer cells. Without the neovascular formation, tumour volumes cannot increase and undergo metastasis. Antiangiogenesis is one of the most promising approaches for antitumour therapy. The exploration of new antiangiogenic agents would be helpful in antitumour therapy. Quinoline is an aromatic nitrogen compound characterized by a double-ring structure which exhibits a benzene ...

PodMed: A Medical News Roundup From Johns Hopkins (with audio)

Sat, 26 Mar 2016 18:00:00 +0100

(MedPage Today) -- This weeks topics include early parental nutrition, meditation for low back pain, use of complementary medicine by seniors, and non-invasive ventilation after abdominal surgery (Source: MedPage Today Psychiatry)

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Dry matter and digesta particle size gradients along the goat digestive tract on grass and browse diets

Sat, 26 Mar 2016 17:22:19 +0100

Summary Physical properties of the digesta vary along the ruminant digestive tract. They also vary within the forestomach, leading to varying degrees of rumen contents stratification in ‘moose‐type’ (browsing) and ‘cattle‐type’ (intermediate and grazing) ruminants. We investigated the dry matter concentration (DM) and the mean digesta particle size (MPS) within the forestomach and along the digestive tract in 10 goats fed grass hay or dried browse after a standardized 12‐h fast, euthanasia and freezing in the natural position. In all animals, irrespective of diet, DM showed a peak in the omasum and an increase from caecum via colon towards the faeces and a decrease in MPS between the reticulum and the omasum. Both patterns are typical for ruminants in general. In the forestom...

Evidence for, and Associated Risks with, the Human Chorionic Gonadotropin Supplemented Diet.

Sat, 26 Mar 2016 16:51:01 +0100

Authors: Butler SA, Cole LA Abstract Trend diets can be commonplace amongst those who are trying to lose weight but in most cases there is some shred of evidence to suggest they might be of some benefit. Seldom is there a diet which is such a fad that it is not only completely unfounded but also potential harmful. The human chorionic gonadotropin or "hCG diet" is such a diet, which after half a century still has no evidence to support its efficacy; in fact all scientific publications subsequent to the original article counter these claims. In this short communication, we review the literature and present data on exactly what some of the hCG diet preparations actually contain and highlight that, based on current data, these may do more harm than good. It is worrying that more consid...

A review of prevention strategies for gestational diabetes: is there a missing x-factor?

Sat, 26 Mar 2016 11:41:02 +0100

Authors: Castorino K, Bradley PK, Truong L, Martinez J Abstract Gestational Diabetes affects up to one in five pregnancies and can have significant consequences for both mother and baby. There have been great efforts to identify strategies to prevent gestational diabetes during pregnancy. These efforts have been extended to the pre-pregnancy and postpartum periods to address limitations during pregnancy. In this review we explore how diet, exercise and lifestyle modification can be used to prevent gestational diabetes. PMID: 27012154 [PubMed - as supplied by publisher] (Source: Minerva Endocrinologica)

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Influences of Nutrition Supply and Pathways on the Degenerative Patterns in Human Intervertebral Disc

Sat, 26 Mar 2016 08:25:24 +0100

Conclusion. Impairment of different nutrition pathways results in different degenerative patterns. Level of Evidence: N/A (Source: Spine)

A Common Clinical Dilemma: Management of Abnormal Vaginal Cytology and Human Papillomavirus Test Results

Sat, 26 Mar 2016 08:13:15 +0100

Conclusions: Vaginal cancer is rare, and asymptomatic low-risk women should not be screened. An algorithm based on expert opinion is proposed for managing women with abnormal vaginal test results. (Source: Journal of Lower Genital Tract Disease)

Medical News Today: Fruit juices and smoothies have 'unacceptably high' sugar content

Sat, 26 Mar 2016 07:00:00 +0100

Fruit juices and smoothies may contain more sugar than you expect. New research reveals that one juice may contain a child's recommended sugar intake for a whole day. (Source: Health News from Medical News Today)

NewsCAP: New U.S. dietary guidelines focus on healthy eating patterns and exercise.

Sat, 26 Mar 2016 06:14:02 +0100

Authors: PMID: 27011125 [PubMed - in process] (Source: The American Journal of Nursing)

Serum Phosphate modifies the vascular response to vitamin D receptor activation in Chronic Kidney Disease (CKD) patients

Fri, 25 Mar 2016 23:00:00 +0100

Conclusions The beneficial effect of PCT on endothelial function in CKD is maximal in patients with no or minimal changes in phosphate and it is abolished in patients with a pronounced phosphate rise. These findings generate the hypothesis that the endothelium protective effect by VDRA may be potentiated by phosphate lowering interventions. (Source: Nutrition, Metabolism and Cardiovascular Diseases)

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Brain-specific natriuretic peptide receptor-B deletion attenuates high-fat diet-induced visceral and hepatic lipid deposition in mice

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: Available online 25 March 2016 Source:Peptides Author(s): Yui Yamashita, Nobuko Yamada-Goto, Goro Katsuura, Yukari Ochi, Yugo Kanai, Yuri Miyazaki, Koichiro Kuwahara, Naotetsu Kanamoto, Masako Miura, Akihiro Yasoda, Kousaku Ohinata, Nobuya Inagaki, Kazuwa Nakao C-type natriuretic peptide (CNP) and its receptor, natriuretic peptide receptor-B (NPR-B), are abundantly distributed in the hypothalamus. To explore the role of central CNP/NPR-B signaling in energy regulation, we generated mice with brain-specific NPR-B deletion (BND mice) by crossing Nestin-Cre transgenic mice and mice with a loxP-flanked NPR-B locus. Brain-specific NPR-B deletion prevented body weight gain induced by a high-fat diet (HFD), and the mesenteric fat and liver weights were significant...

Soil microbial carbon use efficiency and biomass turnover in a long-term fertilization experiment in a temperate grassland

Fri, 25 Mar 2016 23:00:00 +0100

In conclusion, the study shows that N availability can control soil C cycling by affecting microbial CUE, while plant community-mediated changes in organic matter inputs and P and K availability played no important role for C partitioning of the microbial community in this temperate grassland. (Source: Soil Biology and Biochemistry)

Human xanthine oxidase recombinant in E. coli: a whole cell catalyst for preparative drug metabolite synthesis

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: Available online 25 March 2016 Source:Journal of Biotechnology Author(s): Márcia Ferreira Antunes, Fabian Kurt Eggimann, Matthias Kittelmann, Stephan Lütz, Steven P. Hanlon, Beat Wirz, Thorsten Bachler, Margit Winkler Human xanthine oxidoreductase (XOR), which is responsible for the final steps of the purine metabolism pathway and involved in oxidative drug metabolism, was successfully expressed in Escherichia coli BL21(DE3) Gold. Recombinant human (rh) XOR yielded higher productivity with the gene sequence optimized for expression in E.coli than with the native gene sequence. Induction of XOR expression with lactose or IPTG resulted in complete loss of activity whereas shake flasks cultures using media rather poor in nutrients resulted in functional XOR expre...

Clove bud (Syzygium aromaticum) improved blood and hepatic antioxidant indices in laying hens receiving low n‐6 to n‐3 ratios

Fri, 25 Mar 2016 23:00:00 +0100

This study was carried out to investigate the effects of different levels of clove bud (Syzygium aromaticum) powder and vitamin E on serum lipid profile, enzyme activities and antioxidant indices, as well as hepatic biochemical and histological alterations in laying hens receiving different n‐6 to n‐3 ratios. A total of 160 laying hens, 43 weeks of age, were allotted to 8 experimental diets with 5 cages of 4 birds each. Dietary treatments consisted of two ratios of n‐6 to n‐3 (16.71 and 2.35), three levels of clove bud (0.0, 2.0 and 4.0 g/kg) and a high vitamin E level (200 mg/kg, as a positive control in each level of n‐6 to n‐3 ratio) in a 2 × 4 factorial arrangement during 70 days of the experiment. Results showed that a decline in the n‐6 to n‐3 ratio led to a red...

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Fatty acid synthase (FASN) gene polymorphism and early lactation milk fat composition in Xinong Saanen goats

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: Available online 26 March 2016 Source:Small Ruminant Research Author(s): Abiel Berhane Haile, Wei Zhang, Wei Wang, Dikun Yang, Yongqing Yi, Jun Luo Fatty Acid Synthase (FASN) is a multifunctional protein, catalyzing the de novo fatty acid (FA) synthesis, its high mRNA expression in goat mammary epithelial cells (GMECs) substantiated by the medium to high heritability of milk fat, makes it a candidate gene for association analysis with milk fat profile. The study aimed to develop markers of Capra hircus FASN to improve healthfulness of goat milk FAs and to investigate early lactation MF profile. 300 milk samples were collected, 30days postpartum, from 300 Saanen does, from 2 herds sired by 73 bucks, and were analyzed with gas-chromatography. Linear mixed models, th...

Effect of dietary extract and dried areal parts of Rosmarinus officinalis on performance, immune responses and total serum antioxidant activity in broiler chicks

Fri, 25 Mar 2016 23:00:00 +0100

Conclusions In conclusion, RP1 and RE1 deteriorated body weight of chickens in different periods. Inclusion of RP2 and RE1 resulted in improved total serum antioxidant activity. (Source: Asian Pacific Journal of Tropical Disease)

Quercetin: A wonder bioflavonoid with therapeutic potential in disease management

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: March 2016 Source:Asian Pacific Journal of Tropical Disease, Volume 6, Issue 3 Author(s): Alka Gupta, Kavita Birhman, Indira Raheja, Surender Kumar Sharma, Hemant Kumar Kar In the last decade, considerable efforts have been made to develop health promising nutritional supplements. Quercetin is a plant-derived bioflavonoid which is recently gaining scientific interest for its antioxidant free radical scavenging effects and anti-inflammatory properties. This wonder flavanol exhibits therapeutic potential in various ailments like cancer, coronary artery, asthma and alzheimer (neurodegeneration) diseases. Additional clinical uses include treatment of inflammatory conditions like gout, pancreatitis and prostatitis. It has been extensively studied for its gastroprotectiv...

High use of complementary and alternative medicine among a large cohort of women with a family history of breast cancer: the Sister Study

Fri, 25 Mar 2016 23:00:00 +0100

Abstract Use of complementary and alternative medicine (CAM) is high among U.S. women, yet information is limited on use among women at increased breast cancer risk. We analyzed CAM use among women with a family history of breast cancer. CAM use was analyzed among women enrolled 2003–2009 in the Sister Study cohort. Eligible women were aged 35–74, U.S. or Puerto Rican residents, no personal history of breast cancer, and had ≥1 sister with breast cancer. Baseline data on CAM use in the past year were available for 49,734 women. Logistic regression models examined the association between CAM use and Gail Model breast cancer risk score. Results were compared to female participants in the 2007 National Health Interview Survey (n = 7965). Among Sister Study participants, there ...

Wild food plants used in traditional vegetable mixtures in Italy

Fri, 25 Mar 2016 23:00:00 +0100

Conclusions Nineteen edible wild plants, such as Asparagus albus L., Campanula trachelium L., Hypochaeris laevigata (L.) Benth. & Hook f., Phyteuma spicatum L., Scolymus grandiflorus Desf., are not yet studied as regards their phytochemical and nutritional profile. Some plants should be avoided due to the presence of toxic compounds such as Adenostyles alliariae (Gouan) A. Kern or Ranunculus repens L. Graphical abstract (Source: Journal of Ethnopharmacology)

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Inhibition of extracellular matrix production and remodeling by Doxycycline in Smooth Muscle Cells

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: Available online 25 March 2016 Source:Journal of Pharmacological Sciences Author(s): Rogelio Palomino-Morales, Carolina Torres, Sonia Perales, Ana Linares, Maria Jose Alejandre Alterations in the extracellular matrix (ECM) production and remodeling of smooth muscle cells (SMCs) have been implicated in processes related to the differentiation in atherosclerosis. Due to the anti-atherosclerotic properties of the tetracyclines, we aimed to investigate whether cholesterol supplementation changes the effect of doxycycline over the ECM proteins synthesis and whether isoprenylated proteins and Rho A protein activation are affected. SMC primary culture isolated from chicks exposed to atherogenic factors in vivo (a cholesterol-rich diet, SMC-Ch), comparing it with control c...

Cytokine Signaling in Skeletal Muscle Wasting

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: Available online 26 March 2016 Source:Trends in Endocrinology & Metabolism Author(s): Jin Zhou, Bin Liu, Chun Liang, Yangxin Li, Yao-Hua Song Skeletal muscle wasting occurs in a variety of diseases including diabetes, cancer, Crohn's disease, chronic obstructive pulmonary disease (COPD), disuse, and denervation. Tumor necrosis factor α (TNF-α) is involved in mediating the wasting effect. To date, a causal relationship between TNF-α signaling and muscle wasting has been established in animal models. However, results from clinical trials are conflicting. This is partly due to the fact that other factors such as TNF-like weak inducer of apoptosis (TWEAK) and interleukin 6 (IL-6) are also involved in skeletal muscle wasting. Because muscle wasting is often a...

Severe Headache or Migraine History Is Inversely Correlated With Dietary Sodium Intake: NHANES 1999–2004

Fri, 25 Mar 2016 23:00:00 +0100

ConclusionsThis study is the first evidence of an inverse relationship between migraine and dietary sodium intake. These results are consistent with altered sodium homeostasis in migraine and our hypothesis that dietary sodium may affect brain extracellular fluid sodium concentrations and neuronal excitability. (Source: Headache: The Journal of Head and Face Pain)

Systematic Review of Factors Influencing Farmers’ Market Use Overall and among Low-Income Populations

Fri, 25 Mar 2016 23:00:00 +0100

Recent evidence indicates a widening gap in fruit and vegetable (F/V) consumption between high- and low-income Americans. This gap is related, in part, to decreased access to food retailers that sell fresh F/V in low-income communities. Farmers’ markets are identified as a strategy for improving F/V consumption by increasing access to these foods. (Source: Journal of the American Dietetic Association)

Moderately high-dose of the artificial sweetener saccharin potentially induces sleep disorders in mice

Fri, 25 Mar 2016 23:00:00 +0100

Caloric sweeteners such as sugar and honey are replaced in thousands of food products by non-caloric artificial sweeteners (NAS). The present study aimed to determine the effects of chronic NAS intake on circadian sleep regulation. (Source: Nutrition)

Systematic Review of Factors Influencing Farmers’ Market Use Overall and among Low-Income Populations

Fri, 25 Mar 2016 23:00:00 +0100

Conclusions There is a need to establish valid and reliable metrics and reporting standards for evaluating farmers’ markets. Findings may inform interventions, programs, and policies to promote farmers’ market use. (Source: Journal of the Academy of Nutrition and Dietetics)

The Biology of Stature

Fri, 25 Mar 2016 23:00:00 +0100

Most pediatricians are attuned to their patients' linear growth (height gain). At each visit, the child's height should be carefully measured and plotted. The clinician can then scrutinize the temporal pattern, and, if the linear growth appears abnormal, initiate an investigation to uncover the underlying problem. Despite this close interest in our patients' statural gains, linear growth itself often is considered as a “black box,” a mysterious process regulated by nutrition, hormones, genetics, and overall health. (Source: The Journal of Pediatrics)

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Correlates of US Adult Physical Activity and Sedentary Behavior Patterns

Fri, 25 Mar 2016 23:00:00 +0100

Conclusions Correlates of physical activity and sedentary behavior patterns were identified from all domains (socio-demographic, acculturation, cardiovascular, and health history). Most correlates that were positively associated with physical activity were negatively associated with sedentary behavior. Better understanding of the correlates of physical activity and sedentary behavior patterns can inform interventions to promote physical activity and reduce sedentary behavior. (Source: Journal of Science and Medicine in Sport)

Prevalence of intestinal helminthic infections and malnutrition among schoolchildren of the Zegie Peninsula, northwestern Ethiopia

Fri, 25 Mar 2016 23:00:00 +0100

A cross-sectional study involving 408 schoolchildren was performed from November 2013 to February 2014 to assess the prevalence of intestinal helminthic infections and malnutrition among schoolchildren of the Zegie Peninsula, northwestern Ethiopia. A structured questionnaire was used to gather data on the demographic and risk factors associated with intestinal helminthic infections. Stool samples were collected and examined for helminth eggs using the formalin–ether concentration technique. In addition, anthropometric measurements were performed to assess the nutritional status of the schoolchildren. (Source: Journal of Infection and Public Health)

IJERPH, Vol. 13, Pages 373: Pathway Analysis Revealed Potential Diverse Health Impacts of Flavonoids that Bind Estrogen Receptors

Fri, 25 Mar 2016 23:00:00 +0100

Flavonoids are frequently used as dietary supplements in the absence of research evidence regarding health benefits or toxicity. Furthermore, ingested doses could far exceed those received from diet in the course of normal living. Some flavonoids exhibit binding to estrogen receptors (ERs) with consequential vigilance by regulatory authorities at the U.S. EPA and FDA. Regulatory authorities must consider both beneficial claims and potential adverse effects, warranting the increases in research that has spanned almost two decades. Here, we report pathway enrichment of 14 targets from the Comparative Toxicogenomics Database (CTD) and the Herbal Ingredients’ Targets (HIT) database for 22 flavonoids that bind ERs. The selected flavonoids are confirmed ER binders from our earlier studies, and...

Influence of nutrient media on callus induction, somatic embryogenesis and plant regeneration in selected Turkish crocus species

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: Available online 26 March 2016 Source:Biotechnology Reports Author(s): Sandeep Kumar Verma, Ashok Kumar Das, Gunce Sahin Cingoz, Emel Uslu, Ekrem Gurel Callus induction, somatic embryogenesis and plant regeneration were initiated in selected five species of Turkish crocus using three diffrent explants (leaf, stem and corm) cultured on four different media (MS, GB5, LS and CHE). The highest frequencies of callus induction (100%) and shoot regeneration (70%, with 7.2 shoots/callus) were found in the crocus species Crocus oliveri ssp. Oliveri, using the MS medium containing 5% (w/v) sucrose supplemented with (4mg/L NAA+4mg/L TDZ) and (2mg/L IAA+2mg/L TDZ+2mg/L BAP). When the embryogenic calli were transferred into the four nutrient media containing (2mg/L IAA+2mg/L TD...

Celastrus Orbiculatus Thunb. Reduces Lipid Accumulation by Promoting Reverse Cholesterol Transport in Hyperlipidemic Mice

Fri, 25 Mar 2016 23:00:00 +0100

Abstract Previously, we found that Celastrus orbiculatus Thunb. (COT) decreases athero-susceptibility in lipoproteins and the aorta of guinea pigs fed a high-fat diet, and increases high-density lipoprotein (HDL). In the present study, we investigated the effect of COT in reducing lipid accumulation and promoting reverse cholesterol transport (RCT) in vivo and vitro. Healthy male mice were treated with high-fat diet alone, high-fat diet with COT (10.0 g/kg/d), or general fodder for 6 weeks. Serum levels of total cholesterol (TC), triglyceride (TG), HDL-C, non-HDL-C, and 3H-cholesterol in plasma, liver, bile, and feces were determined. Pathological changes and the levels of TC and TG in liver were examined. The expression of hepatic genes and protein associated with RCT were anal...

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Severe Headache or Migraine History Is Inversely Correlated With Dietary Sodium Intake: NHANES 1999-2004.

Fri, 25 Mar 2016 23:00:00 +0100

CONCLUSIONS: This study is the first evidence of an inverse relationship between migraine and dietary sodium intake. These results are consistent with altered sodium homeostasis in migraine and our hypothesis that dietary sodium may affect brain extracellular fluid sodium concentrations and neuronal excitability. PMID: 27016121 [PubMed - as supplied by publisher] (Source: Headache)

Effects of Maternal Marginal Iodine Deficiency on Dendritic Morphology in the Hippocampal CA1 Pyramidal Neurons in Rat Offspring

Fri, 25 Mar 2016 23:00:00 +0100

Abstract Although the salt iodization programmes are taken to control iodine deficiency (ID), some regions are still suffering from marginal ID. During pregnancy, marginal ID frequently leads to subtle insufficiency of thyroid hormones, characterized as low serum T4 levels. Therefore, the present research was to explore the effects of maternal marginal ID exposure on dendritic arbor growth in the hippocampal CA1 region and the underlying mechanisms. We established Wistar rat models with ID diet during pregnancy and lactation. The overall daily iodine intakes of the rats were estimated as 7.0, 5.0 and 1.5 μg/day in the control, marginal ID and severe ID groups, respectively. To study the morphological alterations of pyramidal neurons, Golgi–Cox procedure was conducted in the hi...

Aminoacyl-Transfer RNA Synthetases: Connecting Nutrient Status to Angiogenesis Through the Unfolded Protein Response.

Fri, 25 Mar 2016 22:59:02 +0100

Authors: Lounsbury KM, Francklyn CS PMID: 27010025 [PubMed - in process] (Source: Arteriosclerosis, Thrombosis and Vascular Biology)

αVβ3 integrin-targeted microSPECT/CT imaging of inflamed atherosclerotic plaques in mice.

Fri, 25 Mar 2016 22:35:02 +0100

CONCLUSIONS: (99m)Tc-maraciclatide allows in vivo detection of inflamed atherosclerotic plaques in mice and may represent a non-invasive approach for identifying high-risk plaques in patients. PMID: 27009066 [PubMed] (Source: Atherosclerosis)

The Three Biggest Mistakes That I've Made (So Far) As a Health and Wellness Practitioner

Fri, 25 Mar 2016 21:51:58 +0100

I had my first client in 2001 while I was still in massage school. It was in the living-room of the dusty apartment of my neighbor on the big purple massage table that I carted along with me. I remember being terrified that my massage routine wouldn't be long enough to fill the entire 60 minutes (it was--but barely). Despite my initial jitters (and thanks to my very grateful new client), I discovered that I loved doing massage. I kept at it and, quickly realizing that I wanted to learn a lot more about health and wellness so I signed up for as many workshops and trainings as I could in nutrition, energy medicine, yoga, meditation and more. Flash forward several certifications and 15 years later, and I still love health and wellness. While I realize that in the grand scheme of things, 15 ye...

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Nutritionists say 'baffling' official guidance to halve dairy food intake puts public health at risk

Fri, 25 Mar 2016 21:30:30 +0100

Public Health England, the Government's official advisory body on diet, says reducing milk and cheese is vital to cut obesity (Source: Telegraph Health)

What Can The Evolution Of Our Sleep Habits Teach Us?

Fri, 25 Mar 2016 21:20:52 +0100

When Amy Ozski started experiencing insomnia last August, it wasn't due to anything drastic. She recalls a heat wave in the Boston area where she lives, a bit more stress at work, and her schedule being thrown off for a few consecutive days. But the combination was enough to trigger a pattern: Ozski started having trouble falling asleep, and before long the problem snowballed into a chronic issue. Sometimes it would take her hours to fall asleep, or she'd wake up in the middle of the night and struggle to conk out again. Sleep -- and the lack of it -- took over her life. "It was all I thought about during the day," she says. "I was miserable." Ozski tried everything she could think of to fix the problem, from transcendental meditation to acupuncture, but to no avail. Finally, she sought he...

Well: Fruits and Vegetables to Fight Cataracts

Fri, 25 Mar 2016 20:24:19 +0100

Here’s another reason to eat your veggies and fruits high in vitamin C: You may reduce your risk of vision loss from cataracts. (Source: NYT)

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The Icy Fire Beneath Norway's Seabed

Fri, 25 Mar 2016 20:09:38 +0100

This article originally appeared on Arctic Deeply. For weekly updates about Arctic geopolitics, economy, and ecology, you can sign up to the Arctic Deeply email list. -- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website. (Source: Science - The Huffington Post)

Well: Fruits and Vegetables to Fight Cataracts

Fri, 25 Mar 2016 19:42:16 +0100

Here’s another reason to eat your veggies and fruits high in vitamin C: You may reduce your risk of vision loss from cataracts. (Source: NYT)

Impact of Severe Obesity and Weight Loss on Systolic Left Ventricular Function and Morphology: Assessment by 2-Dimensional Speckle-Tracking Echocardiography.

Fri, 25 Mar 2016 19:32:04 +0100

Authors: Karimian S, Stein J, Bauer B, Teupe C Abstract Obesity is associated with an increased risk of heart failure. Little is known about the impact of dietary changes on the cardiac sequelae in obese patients. Twenty-one obese subjects underwent a 12-week low calorie fasting phase of a formula diet. Transthoracic two-dimensional speckle-tracking echocardiography was performed to obtain systolic left ventricular strain before and after weight loss. Body mass index decreased significantly from 38.6 ± 6.2 to 31.5 ± 5.3 kg/m(2), and the total percentage fat loss was 19%. Weight reduction was associated with a reduction in blood pressure and heart rate. Left ventricular longitudinal global peak systolic strain was in the lower normal range (-18.7 ± 3.2%) before weight loss and ...

Well: Fruits and Vegetables to Fight Cataracts

Fri, 25 Mar 2016 19:29:50 +0100

Here’s another reason to eat your veggies and fruits high in vitamin C: You may reduce your risk of vision loss from cataracts. (Source: NYT Health)

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Well: Seeking Painkillers in the Emergency Room

Fri, 25 Mar 2016 19:29:15 +0100

“Why wouldn’t I give patients a Percocet prescription? It makes their life easier and my life easier,” a colleague said to me recently. But that’s not the answer to the opioid epidemic. (Source: NYT)

Relative Abundance in Bacterial and Fungal Gut Microbes in Obese Children: A Case Control Study.

Fri, 25 Mar 2016 19:29:01 +0100

CONCLUSION: Taking into account the complexity of obesity, our data suggest that differences in relative abundance of some core microbial species, preexisting or diet driven, could actively be part of its etiology. This study improved our knowledge about the fungal population in the pediatric school-age population and highlighted the need to consider the influence of cross-kingdom relationships. PMID: 27007700 [PubMed - as supplied by publisher] (Source: Childhood Obesity)

Cells in standby mode

Fri, 25 Mar 2016 18:06:01 +0100

Normally, cells are highly active and dynamic: in their liquid interior, called the cytoplasm, countless metabolic processes occur in parallel, proteins and particles jiggle around wildly. If, however, those cells do not get enough nutrients, their energy level drops. During such unfavorable conditions, the cytoplasm can solidify and protect the cell from death, new research shows. (Source: ScienceDaily Headlines)

Heart Attack Patients Are Getting Younger And Sicker

Fri, 25 Mar 2016 17:00:06 +0100

People who experience the most severe type of heart attack have become younger and more obese in the past two decades, according to a new study. This group is also increasingly more likely to smoke, and to have high blood pressure and diabetes, all of which are preventable risk factors for a heart attack, the researchers found. "On the whole, the medical community has done an outstanding job of improving treatments for heart disease, but this study shows that we have to do better on the prevention side," study co-author Dr. Samir Kapadia, an interventional cardiologist at Cleveland Clinic, said in a statement. "When people come for routine checkups, it is critical to stress the importance of reducing risk factors through weight reduction, eating a healthy diet and being physically active."...

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EndoBreak: Vit D Errors? Docs' Diet Books; Orgasmic Blueberries

Fri, 25 Mar 2016 16:36:01 +0100

(MedPage Today) -- News and highlights from around the endocrinology world (Source: MedPage Today Endocrinology)

Physical activity and screen time in adolescents in the chronic kidney disease in children (CKiD) cohort

Fri, 25 Mar 2016 16:22:21 +0100

Conclusions Adolescents with CKD engage in significantly less PA and greater screen time than healthy youth in the United States, and this may worsen over time. (Source: Pediatric Nephrology)

Scientific and regulatory perspectives in herbal and dietary supplement associated hepatotoxicity in the United States - Avigan MI, Mozersky RP, Seeff LB.

Fri, 25 Mar 2016 16:13:53 +0100

In the United States (US), the risk of hepatotoxicity linked to the widespread use of certain herbal products has gained increased attention among regulatory scientists. Based on current US law, all dietary supplements sold domestically, including botanica... (Source: SafetyLit)

Development of the Community Health Improvement Navigator Database of Interventions

Fri, 25 Mar 2016 16:00:56 +0100

This report describes the development of the database of interventions included in the Community Health Improvement Navigator. The database of interventions allows the user to easily search for multisector, collaborative, evidence-based interventions to address the underlying causes of the greatest morbidity and mortality in the United States: tobacco use and exposure, physical inactivity, unhealthy diet, high cholesterol, high blood pressure, diabetes, and obesity. (Source:

Antibiotics Side Effects on the Mitochondria

Fri, 25 Mar 2016 15:38:08 +0100

Science is just beginning to understand how important your mitochondria are to warding off the diseases of aging. And, as usual, mainstream medicine is lagging way behind. Along with your telomeres, the cellular time keepers at the ends of your chromosomes, your mitochondria are another key component of the anti-aging equation. You see, these tiny organelles in your cells are the power plants that turn fuel into energy for your body. Healthy mitochondria keep you young and energetic.  Research shows that damaged mitochondria can lead to: Schizophrenia and bipolar disorder; Alzheimer’s and Parkinson’s disease; Epilepsy, migraines, and nerve pain; Loss of muscle control and balance; Strokes, heart disease, and coronary artery disease; Chronic fatigue syndrome and fibromyalgia;...

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Why are there apes? Evidence for the co-evolution of ape and monkey ecomorphology.

Fri, 25 Mar 2016 14:43:02 +0100

Authors: Hunt KD Abstract Apes, members of the superfamily Hominoidea, possess a distinctive suite of anatomical and behavioral characters which appear to have evolved relatively late and relatively independently. The timing of paleontological events, extant cercopithecine and hominoid ecomorphology and other evidence suggests that many distinctive ape features evolved to facilitate harvesting ripe fruits among compliant terminal branches in tree edges. Precarious, unpredictably oriented, compliant supports in the canopy periphery require apes to maneuver using suspensory and non-sterotypical postures (i.e. postures with eccentric limb orientations or extreme joint excursions). Diet differences among extant species, extant species numbers and evidence of cercopithecoid diversificat...

A Survey on the Effect of Livestock Production System and Finishing Diet on Sensory Characteristics of Foal Meat Using Generalized Procrustes Analysis.

Fri, 25 Mar 2016 14:23:02 +0100

This study concluded that sensory characteristics of foal meat from a Semi-Extensive Production System with a finishing diet of 3 kg concentrate were more preferable than the other ones. PMID: 27006978 [PubMed - in process] (Source: The Scientific World Journal)

Archaeal Community Changes Associated with Cultivation of Amazon Forest Soil with Oil Palm.

Fri, 25 Mar 2016 14:21:02 +0100

This study compared soil archaeal communities of the Amazon forest with that of an adjacent area under oil palm cultivation by 16S ribosomal RNA gene pyrosequencing. Species richness and diversity were greater in native forest soil than in the oil palm-cultivated area, and 130 OTUs (13.7%) were shared between these areas. Among the classified sequences, Thaumarchaeota were predominant in the native forest, whereas Euryarchaeota were predominant in the oil palm-cultivated area. Archaeal species diversity was 1.7 times higher in the native forest soil, according to the Simpson diversity index, and the Chao1 index showed that richness was five times higher in the native forest soil. A phylogenetic tree of unclassified Thaumarchaeota sequences showed that most of the OTUs belong to Miscellaneo...

Brain Stimulation May Help People With Anorexia

Fri, 25 Mar 2016 14:00:00 +0100

Depression treatment cut urge to restrict food, study says (Source: The Doctors Lounge - Psychiatry)

A twist on the genetic link between Alzheimer’s and heart disease

Fri, 25 Mar 2016 13:30:03 +0100

Alzheimer’s disease often strikes fear in people’s hearts because it gradually erodes a person’s ability to remember, think, and learn. There is no cure, and available treatments alleviate symptoms only temporarily. An estimated 5.3 million Americans currently have Alzheimer’s disease, yet this brain disorder is far less common than heart disease. More than 85 million people in the United States are living with some form of cardiovascular disease or the after-effects of stroke, which also affects brain function. Many people don’t realize that Alzheimer’s and heart disease share a genetic link: the apolipoprotein E gene, also known as ApoE. Genetic testing for ApoE — which is done mainly in research settings and isn’t yet widely available — cannot predict whether a per...

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GI Dynamics taps medtech vet Schorer for CEO | Personnel Moves March 25, 2016

Fri, 25 Mar 2016 13:20:30 +0100

GI Dynamics taps medtech vet Schorer for CEO Troubled GI Dynamics (ASX:GID) said this week that it named a veteran medical device executive, Scott Schorer, to be its new president & CEO effective immediately. Schorer spent the last 6 years as a consultant, advising and helping run companies including stealthy Auris Robotics and Neograft Technologies, and led sales improvement efforts at Medtronic (NYSE:MDT), Zimmer Biomet (NYSE:ZBH), Covidien, Teleflex (NYSE:TFX) and Stryker (NYSE:SYK), according to his LinkedIn profile. He spent a year as Americas president at Systagenix, the wound care business spun out of JNJ in 2009. Schorer was also founder & CEO of Innovative Spinal Technologies for 8 years, before that company declared bankruptcy and was sold to Integra LifeSciences fo...

Pretty Much Nobody In The U.S. Leads A Healthy Lifestyle

Fri, 25 Mar 2016 12:45:07 +0100

Only 2.7 percent of U.S. adults hit the four key metrics of living a healthy lifestyle -- abstaining from smoking, eating well, exercising and maintaining a healthy body fat percentage -- according to a disheartening new study. The study's lifestyle benchmarks for health weren't particularly high. Being smoke-free, exercising moderately and eating USDA recommended foods don't seem like particularly difficult marks to hit. So why do so many Americans fall short of living healthy lives?  "That is the million dollar question," Ellen Smit, a senior author of the study and an associate professor at the Oregon State University College of Public Health and Human Sciences, told The Huffington Post. "We did not look at why few Americans have healthy lifestyles in this study, but I can spe...

New technique promises to banish chunky ankles in 15 minutes

Fri, 25 Mar 2016 12:44:47 +0100

Zebun Islam, a 44-year-old paralegal from London, is a delighted convert to the cankle lift and is thrilled with the results she's got from it. Cankles are probably genetic and are impervious to dieting. (Source: the Mail online | Health)

NewsCAP: New U.S. dietary guidelines focus on healthy eating patterns and exercise

Fri, 25 Mar 2016 12:44:15 +0100

No abstract available (Source: AJN)

CE: Original Research: An Investigation into the Health-Promoting Lifestyle Practices of RNs

Fri, 25 Mar 2016 12:44:15 +0100

Conclusion: This study's findings provided baseline data that will be useful in planning health-promoting lifestyle interventions for participants specific to their institutions, and may help guide future research and educational initiatives related to numerous issues common to the RN workforce. The failure of many nurses to take adequate care of themselves needs to be better understood and addressed, by both individual nurses and their employers. (Source: AJN)

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Well: The Only Girl at Her Science Camp

Fri, 25 Mar 2016 11:22:16 +0100

As a Latina girl who dreams of being a NASA inventor, my 7-year-old daughter’s path is unlikely to be smooth, and the deck remains stacked against her. (Source: NYT)

Longitudinal Changes and Seasonal Variation in Body Composition in Professional Australian Football Players.

Fri, 25 Mar 2016 11:19:02 +0100

CONCLUSIONS: Early career players may benefit from greater emphasis upon specific nutrition and resistance training strategies aimed at increasing FFSTM, whilst all players should balance training and diet towards the end of season to minimise increases in FM. PMID: 27002304 [PubMed - as supplied by publisher] (Source: International Journal of Sports Physiology and Performance)

Symptom Association: An Imperfect Pairing

Fri, 25 Mar 2016 11:13:48 +0100

No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)

The Gut Is a Key Player in Cystic Fibrosis Malnutrition

Fri, 25 Mar 2016 11:13:48 +0100

No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)

Fe-D Up: Ending Iron and Vitamin D Deficiency in Toddlers

Fri, 25 Mar 2016 11:13:48 +0100

No abstract available (Source: Journal of Pediatric Gastroenterology and Nutrition)

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Epigenetics in Paediatric Gastroenterology, Hepatology, and Nutrition: Present Trends and Future Perspectives

Fri, 25 Mar 2016 11:13:48 +0100

ABSTRACT: Epigenetics can be defined as stable, potentially heritable changes in the cellular phenotype caused by mechanisms other than alterations to the underlying DNA sequence. As such, any observed phenotypic changes including organ development, aging, and the occurrence of disease could be driven by epigenetic mechanisms in the presence of stable cellular DNA sequences. Indeed, with the exception of rare mutations, the human genome-sequence has remained remarkably stable over the past centuries. In contrast, substantial changes to our environment as part of our modern life style have not only led to a significant reduction of certain infectious diseases but also seen the exponential increase in complex traits including obesity and multifactorial diseases such as autoimmune disorders. ...

Serum Autotaxin Activity Correlates With Pruritus in Pediatric Cholestatic Disorders

Fri, 25 Mar 2016 11:13:48 +0100

Objective: Pruritus is a common symptom of cholestatic liver disorders. The present study aimed at evaluating autotaxin (ATX), a lysophospholipase recently identified as potential cause for cholestatic pruritus, in pediatric cholestatic diseases presenting with or without itching. Methods: A cohort of 45 children consisting of 14 patients experiencing itching (Alagille syndrome [n = 10], complete extrahepatic biliary atresia [n = 2], neonatal sclerosing cholangitis (n = 1), progressive familial intrahepatic cholestasis type 2 [n = 1]), 9 patients with bile acid synthesis defects (3β-hydroxy-C27-steroid-oxidoreductase [n = 7] and Δ4–3-oxosteroid-5β-reductase deficiency [n = 2]), and 22 healthy children were studied. Serum ATX activity and total serum bile salt ...

Home-Based Screening for Biliary Atresia Using Infant Stool Color Cards in Canada: Quebec Feasibility Study

Fri, 25 Mar 2016 11:13:48 +0100

Conclusions: The high enrollment and utilization rates in this screening study strongly support the feasibility of implementing a Canadian SCC screening program to improve outcomes of children with BA. (Source: Journal of Pediatric Gastroenterology and Nutrition)

Hepatoblastoma in Children With Congenital Portosystemic Shunts

Fri, 25 Mar 2016 11:13:48 +0100

ABSTRACT: Two children developed hepatoblastoma concurrent with congenital portosystemic shunts (PSSs) (Abernethy malformations). Both underwent operative ligation of their PSSs. One received concurrent tumor resection, whereas the other was deemed initially unresectable and underwent biopsy followed by neoadjuvant chemotherapy. Although benign hepatic masses, such as focal nodular hyperplasia and nodular regenerative hyperplasia, are common in patients with Abernethy malformations, malignant tumors have also been documented and should always be considered in the differential diagnosis of a patient with a congenital PSS and a hepatic mass. (Source: Journal of Pediatric Gastroenterology and Nutrition)

Resolution of Hepatic Artery Thrombosis in 2 Pediatric Liver Transplant Patients

Fri, 25 Mar 2016 11:13:48 +0100

ABSTRACT: Hepatic artery thrombosis (HAT) is a serious complication after liver transplantation. This is the first report of spontaneous resolution of HAT in pediatric liver transplant patients on low molecular weight heparin therapy. A total of 2 patients, a 26-month-old boy who presented with acute liver failure and required emergent liver transplantation and a 15-year-old boy with ulcerative colitis and autoimmune hepatitis-primary sclerosing cholangitis overlap underwent liver transplantation for progressive cirrhosis; both developed HAT during the postoperative period. They were both treated with low molecular weight heparin. Follow-up imaging for both patients showed resolution of HAT without evidence of collateral flow. (Source: Journal of Pediatric Gastroenterology and Nutrition)

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Liver Disease in Pediatric Patients With Ataxia Telangiectasia: A Novel Report

Fri, 25 Mar 2016 11:13:48 +0100

Objective: Ataxia telangiectasia (A-T) is a rare genetic multiorgan disease. Although gastrointestinal involvement is known, hepatic involvement in A-T has not been investigated. We aimed to study the hepatic involvement in a large cohort of patients with A-T. Methods: A retrospective review of patients, studied from January 1986 to January 2015 at a National A-T Center. Clinical data including demographic, genetic, laboratory, nutritional, radiographic, and histological data were retrieved. Results: Fifty-three patients, 27 (49%) boys, age 14.6 ± 5.2 years (range 5.9–26.1 years), were included. Twenty-three patients (43.4%), age 9.9 ± 5.1 years, had consistently abnormal liver enzymes. The mean enzyme levels were alanine aminotransferase 76.8 ± 73.8 IU/L, aspartate am...

Temporal Association Between Reflux-like Behaviors and Gastroesophageal Reflux in Preterm and Term Infants

Fri, 25 Mar 2016 11:13:48 +0100

Conclusions: The prevalence of GER as detected by MII-pH was low (10%) in symptomatic preterm and term infants. The incidence and pattern of GER was similar in preterm and term infants. The majority of suspected clinical reflux behaviors did not correlate with reflux events. (Source: Journal of Pediatric Gastroenterology and Nutrition)

Endoscopic Surveillance After Repair of Oesophageal Atresia: Longitudinal Study in 209 Patients

Fri, 25 Mar 2016 11:13:48 +0100

Conclusions: EFU revealed frequent oesophagitis and metaplasia, but no dysplasia or cancer. Routine endoscopic surveillance had limited benefit and seems unnecessary during childhood after repair of OA. (Source: Journal of Pediatric Gastroenterology and Nutrition)

Novel Associations Between Major Histocompatibility Complex and Pediatric-onset Inflammatory Bowel Disease

Fri, 25 Mar 2016 11:13:48 +0100

This study focused on MHC association of genes with pediatric-onset IBD and its different phenotypes. Methods: Blood samples of 103 patients with pediatric IBD (Crohn disease or ulcerative colitis) were collected at Children's Hospital, University of Helsinki, Finland. HLA-A, -B, -DRB1 alleles and complement C4A and C4B gene copy numbers were determined and constructed into haplotypes by a Bayesian algorithm (PHASE). A general population cohort (n = 149) served as a control. HLA-alleles and C4 deficiency frequencies were compared between patients and controls with χ2-squared and Fisher exact test with Bonferroni correction (Pcorr). Results: One MHC haplotype HLA-A*03; HLA-B*07; 1 C4A gene; 1 C4B gene; HLA-DRB1*15 was more common in Crohn disease and ulcerative colitis than in contro...