Subscribe: MedWorm: Antiphospholipid Syndrome
http://www.medworm.com/rss/medicalfeeds/conditions/Antiphospholipid-Syndrome.xml
Preview: MedWorm: Antiphospholipid Syndrome

MedWorm: Antiphospholipid Syndrome News



MedWorm.com provides a medical RSS filtering service. Thousands of medical RSS feeds are combined and output via different filters. This feed contains the latest news in Antiphospholipid Syndrome



Last Build Date: Sun, 31 Dec 2017 22:26:33 +0100

 



Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis

Tue, 28 Nov 2017 00:00:00 +0100

Blood coagulation functions as part of the innate immune system by preventing bacterial invasion, and it is critical to stopping blood loss (hemostasis). Coagulation involves the external membrane surface of activated platelets and leukocytes. Using lipidomic, genetic, biochemical, and mathematical modeling approaches, we found that enzymatically oxidized phospholipids (eoxPLs) generated by the activity of leukocyte or platelet lipoxygenases (LOXs) were required for normal hemostasis and promoted coagulation factor activities in a Ca2+- and phosphatidylserine (PS)–dependent manner. In wild-type mice, hydroxyeicosatetraenoic acid–phospholipids (HETE-PLs) enhanced coagulation and restored normal hemostasis in clotting-deficient animals genetically lacking p12-LOX or 12/15-LOX act...

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.




Heartbroken woman, 23, who lost five babies in six years

Wed, 08 Nov 2017 16:05:12 +0100

Shannon Reed, 23, from Prudhoe, near Newcastle, has been diagnosed with 'sticky blood syndrome', or antiphospholipid syndrome - after years of mystery surrounding her miscarriages. (Source: the Mail online | Health)



Antiphospholipid syndrome: diagnosis and management

Wed, 13 Sep 2017 13:19:52 +0100

Dr Anisur Rahman and Dr Salma Ahmed discuss the diagnosis and management of antiphospholipid syndrome (APS). (Source: GP Online Education)



Heparin, ASA Aids Live Birth With Antiphospholipid Antibody Heparin, ASA Aids Live Birth With Antiphospholipid Antibody

Thu, 20 Jul 2017 16:57:19 +0100

Unfractionated heparin added to aspirin is superior to aspirin alone in promoting live births among women with antiphospholipid syndrome and recurrent pregnancy loss, a meta-analysis shows.Medscape Medical News (Source: Medscape Medical News Headlines)



Prevalence of Antiphospholipid Syndrome Up for Roma SLE

Wed, 14 Jun 2017 17:00:00 +0100

Roma systemic lupus erythematosus patients also have significantly higher prevalence of abortions (Source: The Doctors Lounge - Oncology)



Antiphospholipid Syndrome: Role of Vascular Endothelial Cells Antiphospholipid Syndrome: Role of Vascular Endothelial Cells

Mon, 05 Jun 2017 05:14:47 +0100

This review explores the role of vascular endothelial cell dysfunction in antiphospholipid syndrome, an autoimmune prothrombotic condition. Might this pathway provide a viable target for therapy?Journal of the American College of Cardiology (Source: Medscape Today Headlines)

MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.




Gut bacteria may be a trigger for antiphospholipid syndrome

Sun, 13 Nov 2016 20:49:53 +0100

The gut microbiomes of patients with antiphospholipid syndrome show higher levels of phospholipid-producing bacteria, and this findings point to microbes being a trigger for this life-threatening disease, according to new research. (Source: ScienceDaily Headlines)



Rivaroxaban 'could be a safe treatment option for antiphospholipid syndrome'

Mon, 29 Aug 2016 23:00:00 +0100

The drug rivaroxaban could be an effective means of treating some patients with thromboticantiphospholipid syndrome, according to a new study. Led by University College London and funded byArthritis Research UK, the research has suggested that the drug - which works by inhibiting the formation of blood clots - could be a useful tool in the treatment of those with this serious condition, which affects approximately 15 per cent of patients withlupus and may also occur on its own. The danger of antiphospholipid syndrome Thrombotic antiphospholipid syndrome is classified as a rare condition, but is probably underdiagnosed. It is characterised by the formation of potentially dangerous blood clots in the veins or the arteries. Some patients also suffer recurrent miscarriages, though that aspect ...



Antiphospholipid Syndrome

Mon, 29 Aug 2016 07:00:00 +0100

Title: Antiphospholipid SyndromeCategory: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 8/29/2016 12:00:00 AM (Source: MedicineNet Arthritis General)



Pravastatin Shows Promise in Pregnant Women With Antiphospholipid Syndrome Pravastatin Shows Promise in Pregnant Women With Antiphospholipid Syndrome

Mon, 01 Aug 2016 20:47:59 +0100

Pravastatin may improve pregnancy outcomes in women with antiphospholipid syndrome (APS) refractory to standard antithrombotic therapy, a new study suggests.Reuters Health Information (Source: Medscape Medical News Headlines)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.




I Never Thought Stroke Would Happen to Me

Fri, 13 May 2016 22:07:31 +0100

by Myra Wilson, Stroke Survivor On November 3, 2014, I was in nursing school working as a student nurse at a hospital in Seattle. My first sign that something was not quite right was when I was walking through the nursing station and both of my eyes went blurry. I could still see color but I couldn't see letters. It was blurry for about 30 seconds before clearing up again. I was going to lunch and went to give a report to another nurse. The nurse noticed while I was speaking that I slurred my speech. I didn't notice my speech was slurred at all. It was at that time that I experienced a sudden sharp pain on the right side of my head. The nurse then expressed concern that I was having a stroke and called a code. I was told to sit in the nearby chair. Within minutes a team of people arr...



Can Infections Trigger Autoimmunity? (CME/CE)

Tue, 10 May 2016 16:35:03 +0100

(MedPage Today) -- Case reports suggest a post-infectious association with antiphospholipid syndrome (Source: MedPage Today State Required CME)



Newer Anticoagulants Helpful in Antiphospholipid Syndrome (CME/CE)

Fri, 12 Feb 2016 18:00:00 +0100

(MedPage Today) -- But lack of reversal agents for some complicates the picture (Source: MedPage Today Cardiovascular)



Osmosis Question of the Week Feb 5, 2016Osmosis Question of the Week Feb 5, 2016

Fri, 05 Feb 2016 14:37:41 +0100

This week's question involves antiphospholipid syndrome. Osmosis (Source: Medscape Today Headlines)



Antibody Signals Adverse Pregnancy Outcome (CME/CE)

Fri, 22 Jan 2016 13:38:27 +0100

(MedPage Today) -- Lupus anticoagulant was the only antiphospholipid antibody linked with poor birth outcome (Source: MedPage Today OB/GYN)

MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.




What Are Common Inherited Thrombophilias?

Mon, 25 May 2015 00:06:02 +0100

Discussion Thrombophilia is the increased risk of thromboembolic disease due to a disorder. Thrombophilia can be inherited or acquired (such as antiphospholipid syndrome). The risk of thromboembolic events is much lower in children than adults. At-risk patients should avoid: Dehydration Sitting for prolonged time periods during travel Obesity Smoking Estrogen containing oral contraceptives Common inherited thrombophilias include: Prothrombin (Factor II mutation) Second most common Genetics: 1-2% prevalence is variable depending on location and ethnic background. Cause: Abnormal point mutation of the prothrombin gene that causes increased levels of prothrombin, the precursor of thrombin. Protein C Relatively common Genetics and epidemiology – 0.2% prevalence of general populati...



Thrombotic Complications Still a Problem in APS (CME/CE)

Thu, 14 May 2015 19:30:00 +0100

(MedPage Today) -- Events and related deaths persist in patients with antiphospholipid syndrome. (Source: MedPage Today Cardiovascular)



Woman heartbroken after suffering SEVEN miscarriages finally has a baby

Thu, 19 Feb 2015 20:48:45 +0100

Samantha Bourner, 33, from Kent, suffered recurrent miscarriages due to Antiphospholipid syndrome, which increases the chance of blood clots and raises the risk of miscarriage. (Source: the Mail online | Health)



Genes Predict Thombotic Risk

Sat, 22 Nov 2014 03:13:03 +0100

(MedPage Today) -- Screen for antiphospholipid antibodies in patients with autoimmune diseases. (Source: MedPage Today Primary Care)



Drug Target Linked to Antiphospholipid SyndromeDrug Target Linked to Antiphospholipid Syndrome

Thu, 24 Jul 2014 15:42:11 +0100

The mammalian target of rapamycin complex pathway is activated in the vascular lesions that occur in patients with antiphospholipid syndrome. Medscape Medical News (Source: Medscape Medical News Headlines)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.




Antiphospholipid Antibodies and Bleeding From Renal BiopsyAntiphospholipid Antibodies and Bleeding From Renal Biopsy

Wed, 16 Jul 2014 14:41:03 +0100

A study identified the clinical and histologic risk factors for bleeding after renal biopsy in patients with lupus nephritis. Medscape Rheumatology (Source: Medscape Rheumatology Headlines)



Headaches, fatigue, dizziness and memory problems: Hughes Syndrome explained

Tue, 20 May 2014 23:01:00 +0100

AS PART of Hughes Syndrome Awareness Month, experts explain the little-known disease, also known as Antiphospholipid Syndrome and more common than Parkinson's and multiple sclerosis, and advise what to do if you think might be at risk (Source: Daily Express - Health)



Neonatal Antiphospholipid Syndrome

Thu, 01 May 2014 00:00:00 +0100

Antiphospholipid antibody syndrome (APS) during pregnancy may result in pregnancy morbidity and passive transfer of antibodies to the fetus, resulting in an increased risk of prematurity, intrauterine growth restriction, thrombocytopenia, and developmental delay. Antiphospholipid antibodies may have an impact on neurodevelopment during fetal life. Although rare, persistence of these antibodies in the neonate may lead to thromboembolism, particularly if there is a concurrent infection and/or inherited thrombophilic disorders. Affected pregnant women need to be identified early during gestation so that they can have close monitoring of the placental circulation, fetal growth and development, and testing of serum antiphospholipid antibody levels. Neonates born to mothers with antiphospholipid...



TLC Immunostaining for Detection of “Antiphospholipid” Antibodies

Fri, 07 Feb 2014 22:32:20 +0100

Thin-layer chromatography (TLC) is a nonquantitative technique, which has been employed in the detection of antiphospholipid (aPL) antibodies. Antiphospholipid syndrome (APS) is the most frequently acquired thrombophilia, characterized by thrombosis and obstetric manifestations associated to an autoimmune trait, represented by the positivity of antiphospholipid (aPL) antibodies. Immunoassays for anticardiolipin (aCL) and anti-β2 glycoprotein I (aβ2GPI) antibodies and clotting tests for lupus anticoagulant (LA) represent the standard tests for the routine detection of aPL. The term “seronegative APS” has been used to describe patients with clinical manifestation of APS and persistently negative aPL assessed with routine assays. TLC immunostaining is a useful method for...



Measurement of Malondialdehyde, Glutathione, and Glutathione Peroxidase in SLE Patients

Fri, 07 Feb 2014 22:32:19 +0100

Oxidative stress contributes to chronic inflammation of tissues and plays a central role in immunomodulation, which may lead to autoimmune diseases such as systemic lupus erythematosus (SLE) and antiphospholipid syndrome. Markers of oxidative damage include malondialdehyde (MDA), antioxidant scavengers as glutathione (GSH), and glutathione peroxidase (GSH Px), which all correlate well with SLE disease activity. Amelioration of some clinical manifestations of SLE may be expected by targeting lipid peroxidation with dietary or pharmacological antioxidants. (Source: Springer protocols feed by Immunology)

MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.




Laboratory Tests for the Antiphospholipid Syndrome

Fri, 07 Feb 2014 22:32:18 +0100

Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by recurrent vascular thrombosis (VT) and/or pregnancy morbidity (PM) in the presence of persistent antiphospholipid antibodies (aPL), detected by lupus anticoagulant (LA), anticardiolipin (aCL) antibody, and/or anti‐β2 glycoprotein I (aβ2GPI) antibody assays. These aPL, considered to be diagnostic markers and pathogenic drivers of APS, are a heterogeneous group of antibodies directed against anionic phospholipids, phospholipid-binding plasma proteins, and phospholipid–protein complexes. Although APS is currently considered as a single disease, it presents with a wide range of clinical symptoms and biological characteristics. The clinical diagnosis of APS in a patient with symptoms and signs is de...



IgA Antiphospholipid Antibodies: Growing Clinical RelevanceIgA Antiphospholipid Antibodies: Growing Clinical Relevance

Fri, 17 Jan 2014 13:00:00 +0100

Testing for these autoantibodies may identify additional patients with clinical features of antiphospholipid antibody syndrome. Medscape Rheumatology (Source: Medscape Rheumatology Headlines)



Antiphospholipid Syndrome

Fri, 10 Jan 2014 07:00:00 +0100

Title: Antiphospholipid SyndromeCategory: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 1/10/2014 12:00:00 AM (Source: MedicineNet Arthritis General)



Biomarker Predicts Poor Pregnancy Outcomes in Lupus, APLBiomarker Predicts Poor Pregnancy Outcomes in Lupus, APL

Tue, 29 Oct 2013 19:37:46 +0100

Angiogenic factor dysregulation early in pregnancy can predict pre-eclampsia and poor fetal and maternal outcomes, enabling early intervention in women with lupus or antiphospholipid syndrome (APL). Medscape Medical News (Source: Medscape Today Headlines)



Aspirin Prophylaxis Adequate for Antiphospholipid AntibodiesAspirin Prophylaxis Adequate for Antiphospholipid Antibodies

Tue, 22 Oct 2013 16:00:00 +0100

Adding warfarin to aspirin doesn't seem to improve thromboprophylaxis in patients with antiphospholipid antibodies (aPL), according to results from the ALIWAPAS study. Reuters Health Information (Source: Medscape Medical News Headlines)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.




Invasive Aspergillosis vs Antiphospholipid SyndromeInvasive Aspergillosis vs Antiphospholipid Syndrome

Tue, 24 Sep 2013 20:19:07 +0100

Invasive aspergillosis is a frequently missed diagnosis. This case study tells why. American Journal of Critical Care (Source: Medscape Today Headlines)



Antiphospholipid Antibodies and Increased Stillbirth RiskAntiphospholipid Antibodies and Increased Stillbirth Risk

Mon, 19 Aug 2013 16:00:00 +0100

Women with increased antiphospholipid antibody levels face a threefold increased risk of stillbirth, a new study shows. Reuters Health Information (Source: Medscape Medical News Headlines)



Genetics Home Reference: antiphospholipid syndrome

Thu, 13 Jun 2013 13:20:28 +0100

(Source: NLM General Announcements)



Rituximab for the Antiphospholipid Antibody SyndromeRituximab for the Antiphospholipid Antibody Syndrome

Thu, 14 Mar 2013 14:35:14 +0100

Dr. Kevin Deane comments on a pilot study of rituximab for the treatment of antiphospholipid syndrome. Medscape Rheumatology (Source: Medscape Today Headlines)



HPV, tetanus vaccines causes deadly new autoimmune disease known as antiphospholipid syndrome

Tue, 12 Feb 2013 06:00:00 +0100

One of the latest technologies being employed in the production of new vaccines involves the use of outer membrane vesicles (OMVs), a type of pathogenic bacteria that mimics the phospholipids naturally found in the human body, as customizable vaccine adjuvants. But vaccines... (Source: NaturalNews.com)

MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.




Revised Article-Antiphospholipid Antibody Syndrome

Wed, 23 May 2012 00:00:00 +0100

Antiphospholipid antibody syndrome is an autoimmune disorder. (Source: National Heart, Lung, and Blood Institute Health Topics)



Revised Article-Antiphospholipid Antibody Syndrome-APS

Wed, 01 Sep 2010 00:00:00 +0100

Antiphospholipid antibody syndrome, APS, is an autoimmune disorder. (Source: National Heart, Lung, and Blood Institute Health Topics)