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Preview: MedWorm: Lyme Disease

MedWorm: Lyme Disease



MedWorm.com provides a medical RSS filtering service. Over 7000 RSS medical sources are combined and output via different filters. This feed contains the latest news and research in the Lyme Disease category.



Last Build Date: Tue, 29 Mar 2016 16:31:40 +0100

 



Real-Time PCR studies regarding the borrelia burgdorferi, francisella tularensis, tick borne encephalitis virus (TBEv) and crimeean congo hemorrhagic fever virus (CCHFv) occurrence in the Romanian ticks

Tue, 29 Mar 2016 09:23:38 +0100

Background: Our studies undertaken between 2006-2015 have shown that the most frequent species of ticks in Romania is Ixodes ricinus. It was found that I. ricinus is the main vector in Romania for the Borrelia burgdorferi s.l. and for the TBEv, but no data were available for Francisella tularensis and CCHFv infectious agents occurrence into I.ricinus and Hyalomma sp. (Source: International Journal of Infectious Diseases)

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An Open Letter to the Boston Globe About Lyme Disease

Mon, 28 Mar 2016 19:45:00 +0100

Today, the Boston Globe editorial board spoke out against a bill "that would require insurers in Massachusetts to cover Lyme disease treatments for as long as a doctor says they're needed." The Globe writes: Lawmakers may have good intentions, but they don't possess the expertise to decide whether it's beneficial, cost-efficient, or safe, to keep using strong medicines to treat a condition the medical establishment doubts is real. Such questions should be resolved by a consensus of doctors and researchers -- and buttressed by convincing clinical date [sic] -- not determined by legislative mandate. Who among the Boston Globe editorial board possesses the medical expertise to make this call is not disclosed, but this information would be useful given that the Globe's stance presumes absolute...



Susceptibility, likelihood to be diagnosed, worry and fear for contracting Lyme disease

Fri, 25 Mar 2016 23:00:00 +0100

This study investigates the four separate outcomes of susceptibility, likelihood to be diagnosed, worry, and fear for contracting Lyme disease. University students (n=713) were surveyed about demographics, perceived health, Lyme disease knowledge, Lyme disease preventive behaviors, Lyme disease history, and Lyme disease miscellaneous variables. We found that women were associated with increased susceptibility and fear. (Source: Journal of Infection and Public Health)



Lyme: Fight Harder For Science and End This War

Fri, 25 Mar 2016 18:09:08 +0100

I just had a flashback. When I was diagnosed with Lyme, I knew little about it. I went to the first infectious disease doctor with my bullseye still present, asking lots of questions. Among them, are you sure this three weeks of doxycycline is enough. He smiled, and with his eyes fixed on his computer, he said, "Yes, it's more than enough. In fact, I could just tell you to take ten days but then you'd come back later if anything went haywire and ask why I didn't give you twenty-one." He looked up, "Call me if anything goes crazy." A month later, I called. I woke up with a very sore throat and fever two days before my brother's wedding and a gland in my neck that felt like a pulsating grape. It was movable but scarily large. He said if it didn't go down in a few weeks, to let him know. It d...



Antibiotics Side Effects on the Mitochondria

Fri, 25 Mar 2016 15:38:08 +0100

Science is just beginning to understand how important your mitochondria are to warding off the diseases of aging. And, as usual, mainstream medicine is lagging way behind. Along with your telomeres, the cellular time keepers at the ends of your chromosomes, your mitochondria are another key component of the anti-aging equation. You see, these tiny organelles in your cells are the power plants that turn fuel into energy for your body. Healthy mitochondria keep you young and energetic.  Research shows that damaged mitochondria can lead to: Schizophrenia and bipolar disorder; Alzheimer’s and Parkinson’s disease; Epilepsy, migraines, and nerve pain; Loss of muscle control and balance; Strokes, heart disease, and coronary artery disease; Chronic fatigue syndrome and fibromyalgia;...






The diagnostic accuracy of serological tests for Lyme borreliosis in Europe: a systematic review and meta-analysis

Fri, 25 Mar 2016 00:00:00 +0100

Interpretation of serological assays in Lyme borreliosis requires an understanding of the clinical indications and the limitations of the currently available tests. We therefore systematically reviewed the acc... (Source: BMC Infectious Diseases)



Serological survey on some pathogens in wild brown hares (Lepus europaeus) in Central Italy

Tue, 22 Mar 2016 23:00:00 +0100

Conclusion The obtained results showed that B. burgdorferi s.l. N. caninum, T. gondii, A. phagocytophilum and Leishmania sp circulate in wild brown hares in Central Italy, suggesting a possible role of L. europaeus as reservoir of these pathogens. The obtained results showed that autochthonous wild brown hares living in Central Italy have been exposed to several pathogens circulating in this area, suggesting a possible role of L. europaeus as reservoir. (Source: Asian Pacific Journal of Tropical Medicine)



An 89-year-old man presents with worsening heart failure

Tue, 22 Mar 2016 23:00:00 +0100

Clinical introduction An 89-year-old man with a history of heart failure with preserved ejection fraction presented with worsening dyspnoea, reduced exercise capacity and peripheral oedema. His medical history was significant for hypertension, paroxysmal atrial fibrillation (AF), chronic obstructive pulmonary disease and Lyme disease (1983). Admission cardiovascular medications included aspirin 75 mg once a day, perindopril 6 mg once a day, furosemide 40 mg two times a day, flecainide 100 mg two times a day and simvastatin 40 mg one a night. On examination, he was normothermic and clinically in heart failure with raised jugular venous pressure, bibasal pulmonary crepitations and oedema up to abdomen. Cardiac markers were negative. Other laboratory tests demonstrate...






Tick-borne bacterial pathogens in southwestern Finland

Tue, 22 Mar 2016 00:00:00 +0100

Ixodes ricinus and Ixodes persulcatus are the main vectors of Lyme borreliosis spirochetes and several other zoonotic bacteria in northern Europe and Russia. However, few studies scree... (Source: Parasites and Vectors)

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Id: 53: sever symptomatic babesiosis co-infection with lyme disease

Mon, 21 Mar 2016 23:00:00 +0100

Discussion Humans are opportunistic hosts to Babesia when bitten by nymph or adult ticks; the most known ticks are Ixodes. Babesiosis should be considered in patients who have a malaria-like illness in areas endemic for Babesia infection. The symptoms usually begin 2–4 weeks after a tick bite. The presentation includes constitutional symptoms, abdominal pain and dark urine. Labs finding include hemolytic anemia and elevated liver enzymes. Urinalysis reveals hemoglobinuria without red blood cells. The diagnosis of Babesiosis is usually established by microscopic examination of Giems or Wright-stained blood smears, indirect immunofluorescent antibody tests and PCR. In healthy individuals with intact spleens, the symptoms resolve spontaneously without treatment. For mild to moderate bab...



Id: 62: hemophagocytic lymphohistiocytosis caused by infection by ehrlichia chaffeensis: a case report.

Mon, 21 Mar 2016 23:00:00 +0100

We present a case of HLH triggered by severe infection with Ehrlichia chaffeensis in a patient taking methotrexate for seronegative spondyloarthropathy. A 45-year-old man with a history of ankylosing spondylitis taking methotrexate presented to a community hospital with acute onset of nausea, vomiting and diarrhea. Physical examination revealed a febrile patient with diffuse abdominal tenderness with splenomegaly and diffuse maculopapular rash involving the trunk and all extremities. Labs showed leukopenia and thrombocytopenia. Clinical course was complicated by development of acute renal failure, altered mental status and hypoxic respiratory failure requiring endotracheal intubation and mechanical ventilation. Plasmapheresis was initiated due to concern for thrombotic thrombocytopenic pur...



Controversial New Push to Tie Microbes to Alzheimer's Disease

Mon, 21 Mar 2016 20:00:00 +0100

A journal article says herpes virus and Lyme disease bacteria are behind the mind-robbing illness, but not all researchers are convinced -- Read more on ScientificAmerican.com (Source: Scientific American)



Borrelia miyamotoi: A human tick-borne relapsing fever spirochete in Europe and its potential impact on public health

Sun, 20 Mar 2016 23:00:00 +0100

Publication date: Available online 21 March 2016 Source:Advances in Medical Sciences Author(s): Edward Siński, Renata Welc-Falęciak, Joanna Zajkowska Borrelia miyamotoi is a tick-borne bacterium which has only recently been identified in Europe as a human pathogen causing relapsing fever and little is known about its local impact on human health. There are three types of B. miyamotoi: Asian (Siberian), European, and American. B. miyamotoi is transmitted by the same Ixodes ricinus-persulcatus species complex, which also transmits B. burgdorferi s.l., the Lyme borreliosis group. Both Borrelia groups are mostly maintained in natural rodent populations. The aim of this review is to summarize the available literature on B. miyamotoi, with the focus of attention falling on Europe, as well...



Nigeria: Emerging and Re-Emerging Diseases - Call for Timely Public Health Response in Nigeria

Fri, 18 Mar 2016 14:48:37 +0100

[Guardian] At present, the World Health Organisation (WHO) is monitoring a couple of infectious diseases, including: Ebola, Lassa fever, Severe Acute Respiratory Syndrome (SARS), Acquired Immune Deficiency Syndrome (AIDS), Haemorrhagic fever, West Nile Virus, and Lyme disease. The rate of re-emergence of infectious disease has been on the increase. Diseases such as cholera, tuberculosis, Influenza (flu), hepatitis and staphylococcus infections thought to have been controlled are re-emerging. A majority of the agents (Source: AllAfrica News: Health and Medicine)

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Statins reduce spirochetal burden and modulate immune responses in the C3H/HeN mouse model of Lyme disease

Wed, 16 Mar 2016 00:00:00 +0100

Publication date: Available online 16 March 2016 Source:Microbes and Infection Author(s): Tricia A. Van Laar, Camaron Hole, S.L. Rajasekhar Karna, Christine L. Miller, Robert Reddick, Floyd L. Wormley, J. Seshu Lyme disease (LD) is a systemic disorder caused by Borrelia burgdorferi. Lyme spirochetes encode for a functional 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGR EC 1.1.1.88) serving as a rate limiting enzyme of the mevalonate pathway that contribute to components critical for cell wall biogenesis. Statins have been shown to inhibit B. burgdorferi in vitro. Using a mouse model of Lyme disease, we found that statins contribute to reducing bacterial burden and altering the murine immune response to favor clearance of spirochetes. (Source: Microbes and Infection)



CD83 Modulates B Cell Activation and Germinal Center Responses.

Wed, 16 Mar 2016 00:00:00 +0100

Authors: Krzyzak L, Seitz C, Urbat A, Hutzler S, Ostalecki C, Gläsner J, Hiergeist A, Gessner A, Winkler TH, Steinkasserer A, Nitschke L Abstract CD83 is a maturation marker for dendritic cells. In the B cell lineage, CD83 is expressed especially on activated B cells and on light zone B cells during the germinal center (GC) reaction. The function of CD83 during GC responses is unclear. CD83(-/-) mice have a strong reduction of CD4(+) T cells, which makes it difficult to analyze a functional role of CD83 on B cells during GC responses. Therefore, in the present study we generated a B cell-specific CD83 conditional knockout (CD83 B-cKO) model. CD83 B-cKO B cells show defective upregulation of MHC class II and CD86 expression and impaired proliferation after different stimuli. Analys...



[Incidence of Lyme disease in Spain].

Tue, 15 Mar 2016 12:14:01 +0100

Authors: Bonet Alavés E, Guerrero Espejo A, Cuenca Torres M, Gimeno Vilarrasa F PMID: 26971976 [PubMed - as supplied by publisher] (Source: Medicina Clinica)



Blog: Preparing for insect borne diseases

Tue, 15 Mar 2016 12:09:19 +0100

Ticks carrying the bacteria ‘Borrelia’ causing Lyme disease are endemic throughout the UK, and reports of Lyme disease have been steadily increasing with the infection acquired in woodlands, moorlands and parks Hide related content:  Show related content read more (Source: Nursing in Practice)



Notes from the Field: Lymphocytic Choriomeningitis Virus Meningoencephalitis from a Household Rodent Infestation - Minnesota, 2015.

Fri, 11 Mar 2016 14:54:02 +0100

Authors: Talley P, Holzbauer S, Smith K, Pomputius W Abstract On April 20, 2015, a female aged 15 years sought care at her pediatrician's office after 5 days of fever, myalgia, left parietal headache, and photophobia. A rapid influenza assay was negative, and erythrocyte sedimentation rate and total white blood cell count were normal. She improved with symptomatic care at home, but returned to her pediatrician's office on April 28, reporting recurrence of her headache and photophobia and new onset of a stiff neck. She was admitted to the hospital, where she was febrile to 102.9°F (39.4°C) and had meningismus. Computed tomography scan of her head was normal, and a cerebrospinal fluid (CSF) analysis showed a markedly elevated white blood cell count with 68% lymphocytes, low glucose...

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Molecular identification of Borrelia genus in questing hard ticks from Portugal: Phylogenetic characterization of two novel Relapsing Fever-like Borrelia sp.

Fri, 11 Mar 2016 00:00:00 +0100

This study was designed to update the presence of B. burgdorferi s.l. species in ticks from several districts of mainland Portugal, where Ixodes ricinus had been previously described. Ticks (a total of 2915 specimens) were collected in seven districts throughout the country, and analyzed using molecular methods. Three nested-PCR protocols, targeting the flagellin gene (flaB), the intergenic spacer region (IGS) located between 5S and 23S rRNA, and the glpQ gene, and a conventional PCR targeting the 16S rRNA, were used for Borrelia DNA detection. Borrelia DNA was detected in 3% of the ticks from Braga, Vila Real, Lisboa, Setúbal, Évora and Faro districts. The obtained amplicons were sequenced and analyzed by BLASTn, and 15/63 (24%) matched with homologous sequences from Borrelia lusitaniae...



Serological Detection of Borrelia burgdorferi among Horses in Korea.

Thu, 10 Mar 2016 18:29:02 +0100

Authors: Lee SH, Yun SH, Choi E, Park YS, Lee SE, Cho GJ, Kwon OD, Kwak D Abstract Lyme disease is a tick-borne zoonotic infectious disease caused by Borrelia burgdorferi. The present study assessed the infection status of B. burgdorferi among horses reared in Korea using ELISA and PCR. Between 2009 and 2013, blood samples were collected from 727 horses throughout Korea. Data for each animal including age, gender, breed, and region of sample collection were used for epidemiological analysis. Overall, 38 (5.2%; true prevalence: 5.5%) of 727 horses were seropositive by ELISA. There were statistically significant differences according to breed and region (P<0.001) whose differences might be attributed to the ecology of vector ticks and climate conditions. Using 2 nested PCR, none o...



Sony musician Ren Gill to give up career amid Lyme disease battle

Thu, 10 Mar 2016 14:31:20 +0100

Ren Gill, 25, from Brighton, was first diagnosed with depression and bipolar disorder, then chronic fatigue syndrome but was finally diagnosed with Lyme disease at a clinic in Brussels. (Source: the Mail online | Health)



Linkages of Weather and Climate With Ixodes scapularis and Ixodes pacificus (Acari: Ixodidae), Enzootic Transmission of Borrelia burgdorferi, and Lyme Disease in North America

Tue, 08 Mar 2016 00:00:00 +0100

Lyme disease has increased both in incidence and geographic extent in the United States and Canada over the past two decades. One of the underlying causes is changes during the same time period in the distribution and abundance of the primary vectors: Ixodes scapularis Say and Ixodes pacificus Cooley and Kohls in eastern and western North America, respectively. Aside from short periods of time when they are feeding on hosts, these ticks exist in the environment where temperature and relative humidity directly affect their development, survival, and host-seeking behavior. Other important factors that strongly influence tick abundance as well as the proportion of ticks infected with the Lyme disease spirochete, Borrelia burgdorferi, include the abundance of hosts for the ticks and the capaci...



County-Scale Distribution of Ixodes scapularis and Ixodes pacificus (Acari: Ixodidae) in the Continental United States

Tue, 08 Mar 2016 00:00:00 +0100

The blacklegged tick, Ixodes scapularis Say, is the primary vector to humans in the eastern United States of the Lyme disease spirochete Borrelia burgdorferi, as well as causative agents of anaplasmosis and babesiosis. Its close relative in the far western United States, the western blacklegged tick Ixodes pacificus Cooley and Kohls, is the primary vector to humans in that region of the Lyme disease and anaplasmosis agents. Since 1991, when standardized surveillance and reporting began, Lyme disease case counts have increased steadily in number and in geographical distribution in the eastern United States. Similar trends have been observed for anaplasmosis and babesiosis. To better understand the changing landscape of risk of human exposure to disease agents transmitted by I. scapularis an...

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Infection of Immature Ixodes scapularis (Acari: Ixodidae) by Membrane Feeding

Tue, 08 Mar 2016 00:00:00 +0100

A reduction in the use of animals in infectious disease research is desirable for animal welfare as well as for simplification and standardization of experiments. An artificial silicone-based membrane-feeding system was adapted for complete engorgement of adult and nymphal Ixodes scapularis Say (Acari: Ixodidae), and for infecting nymphs with pathogenic, tick-borne bacteria. Six wild-type and genetically transformed strains of four species of bacteria were inoculated into sterile bovine blood and fed to ticks. Pathogens were consistently detected in replete nymphs by polymerase chain reaction. Adult ticks that ingested bacteria as nymphs were evaluated for transstadial transmission. Borrelia burgdorferi and Ehrlichia muris-like agent showed high rates of transstadial transmission to adult ...



New Records of Ixodes affinis (Acari: Ixodidae) Parasitizing Avian Hosts in Southeastern Virginia

Tue, 08 Mar 2016 00:00:00 +0100

This study presents evidence of I. affinis parasitizing five new host passerine species. During 2012–2014, 1,888 birds were captured and examined for ticks, and 18 immature I. affinis were collected from 12 birds—six Carolina Wrens (Thyrothorus ludovicianus); two Brown Thrashers (Toxostoma rufum); and one American Robin (Turdus migratorius), Eastern Towhee (Pipilo erythrophthalmus), Northern Cardinal (Cardinalis cardinalis), and White-throated Sparrow (Zonotrichia albicollis). Of 15 larvae and 3 nymphs collected, one nymph tested positive for B. burgdorferi DNA. I. affinis was found co-feeding on birds with immature Amblyomma americanum (L.), Ixodes brunneus Koch, Ixodes dentatus Marx, Ixodes scapularis Say, and Haemaphysalis leporispalustris Packard. The results of this resear...



Yamamoto new scalp acupuncture, applied kinesiology and breathing exercises for facial paralysis in a young boy caused by Lyme disease – A case report

Tue, 08 Mar 2016 00:00:00 +0100

Discussion The case shows a multimodal approach to facial paralysis integrating pharmacological treatment and CAM including YNSA, Applied Kinesiology and breathing exercises. (Source: EXPLORE: The Journal of Science and Healing)



Cardiac Tropism of

Tue, 08 Mar 2016 00:00:00 +0100

Fatal Lyme carditis caused by the spirochete Borrelia burgdorferi rarely is identified. Here, we describe the pathologic, immunohistochemical, and molecular findings of five case patients. These sudden cardiac deaths associated with Lyme carditis occurred from late summer to fall, ages ranged from young adult to late 40s, and four patients were men. Autopsy tissue samples were evaluated by light microscopy, Warthin-Starry stain, immunohistochemistry, and PCR for B. burgdorferi, and immunohistochemistry for complement components C4d and C9, CD3, CD79a, and decorin. (Source: American Journal of Pathology)



Borrelia burgdorferi induces a type I interferon response during early stages of disseminated infection in mice

Tue, 08 Mar 2016 00:00:00 +0100

Lyme borrelia genotypes differ in their capacity to cause disseminated disease. Gene array analysis was employed to profile the host transcriptome induced by Borrelia burgdorferi strains with different capacities... (Source: BMC Microbiology)

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Cardiac Tropism of Borrelia burgdorferi: An Autopsy Study of Sudden Cardiac Death Associated with Lyme Carditis.

Tue, 08 Mar 2016 00:00:00 +0100

Authors: Muehlenbachs A, Bollweg BC, Schulz TJ, Forrester JD, DeLeon Carnes M, Molins C, Ray GS, Cummings PM, Ritter JM, Blau DM, Andrew TA, Prial M, Ng DL, Prahlow JA, Sanders JH, Shieh WJ, Paddock CD, Schriefer ME, Mead P, Zaki SR Abstract Fatal Lyme carditis caused by the spirochete Borrelia burgdorferi rarely is identified. Here, we describe the pathologic, immunohistochemical, and molecular findings of five case patients. These sudden cardiac deaths associated with Lyme carditis occurred from late summer to fall, ages ranged from young adult to late 40s, and four patients were men. Autopsy tissue samples were evaluated by light microscopy, Warthin-Starry stain, immunohistochemistry, and PCR for B. burgdorferi, and immunohistochemistry for complement components C4d and C9, CD3,...



Cardiac Tropism of Borrelia burgdorferi

Tue, 08 Mar 2016 00:00:00 +0100

Fatal Lyme carditis caused by the spirochete Borrelia burgdorferi rarely is identified. Here, we describe the pathologic, immunohistochemical, and molecular findings of five case patients. These sudden cardiac deaths associated with Lyme carditis occurred from late summer to fall, ages ranged from young adult to late 40s, and four patients were men. Autopsy tissue samples were evaluated by light microscopy, Warthin-Starry stain, immunohistochemistry, and PCR for B. burgdorferi, and immunohistochemistry for complement components C4d and C9, CD3, CD79a, and decorin. (Source: American Journal of Pathology)



Molecular survey on zoonotic tick-borne bacteria and chlamydiae in feral pigeons (Columba livia domestica)

Mon, 07 Mar 2016 00:00:00 +0100

Conclusions Feral pigeons living in urban and periurban areas are a hazard for the human health as source of several pathogens. The obtained results confirm pigeons as reservoirs of chlamydial agents and suggest that they may be involved in the epidemiology of zoonotic tick-borne infections too. (Source: Asian Pacific Journal of Tropical Medicine)



Postepy Hig Med Dosw 2016; 70:180-185 "Serum carnitine concentration is decreased in patients with Lyme borreliosis"

Sat, 05 Mar 2016 08:20:44 +0100

Conclusions: LB patients exhibit a significant decrease of their serum carnitine concentrations. The largest changes were in the NB and PLD patients. To prevent late complications of the disease a possibility of early supplementation with carnitine should be considered. Further studies are required to explain the pathophysiological significance of our findings. (Source: Postepy higieny i medycyny doswiadczalnej)



Geographical differences in seroprevalence of Borrelia burgdorferi antibodies in Norway, 2011–2013

Sat, 05 Mar 2016 00:00:00 +0100

Publication date: Available online 27 February 2016 Source:Ticks and Tick-borne Diseases Author(s): Didrik F. Vestrheim, Richard A. White, Ingeborg S. Aaberge, Audun Aase Detection of specific antibodies against Borrelia burgdorferi sensu lato is a useful aid for the diagnosis of Lyme borreliosis. However, antibodies are present in the general population. The seroprevalence increase with age, and varies according to the prevalence of infected ticks. We performed a seroprevalence study of IgM and IgG antibody reactivity against B. burgdorferi sensu lato in Norway by age-groups and geography, in order to provide a reference set of seroprevalence to inform the interpretation of positive test results. We used two commercially available enzyme immuno assays (EIA) and a multiplexed bead as...

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What Clinicians Should Know About the New Lyme SpeciesWhat Clinicians Should Know About the New Lyme Species

Tue, 01 Mar 2016 21:18:42 +0100

Borrelia burgdorferi isn't the only bacterial species causing Lyme disease in the United States. Learn about emerging tickborne infections and how they differ from 'traditional' Lyme disease. Medscape Infectious Diseases (Source: Medscape Infectious Diseases Headlines)



An Unrecognized Rash Progressing to Lyme Carditis: Important Features and Recommendations Regarding Lyme Disease

Tue, 01 Mar 2016 06:00:00 +0100

We present a case report of 46-year-old man with no medical history, who complained of extreme fatigue, near-syncope, and palpitations. He initially presented in complete heart block. A transvenous pacemaker was placed in the emergency department, and he was started empirically on Ceftriaxone for Lyme disease. He was admitted and over the course of the next few days, his rhythm regressed to Mobitz type I first-degree atrioventricular block and then to normal sinus rhythm. This case report highlights some important features regarding Lyme carditis, a rare presentation of early disseminated Lyme disease (seen in a few weeks to months after the initial tick bite). In 25%–30% of patients, the characteristic targetoid rash may not be seen, a likely culprit of the disease not being detected ea...



Tick-Borne Illnesses

Tue, 01 Mar 2016 06:00:00 +0100

Tick-borne diseases are prevalent throughout the United States. These illnesses are caused by a variety of different pathogens that use ticks as vectors, including bacteria, viruses, rickettsia, and protozoa. Some of the most common illnesses caused by ticks are Lyme disease, Rocky Mountain spotted fever, babesiosis, ehrlichiosis, anaplasmosis, tularemia, Colorado tick fever, tick-borne relapsing fever, and Powassan disease. Unique skin changes, fever, and influenza-like symptoms may indicate tick-borne disease. Early diagnosis can be difficult as well as nonspecific and can resemble overtraining syndrome. Diagnosis is important to facilitate early treatment to decrease morbidity and mortality and should often be initiated before a definitive diagnosis is made. Treatment guidelines are pub...



Emerging Cases of Powassan Virus Encephalitis in New England: Clinical Presentation, Imaging, and Review of the Literature

Tue, 01 Mar 2016 00:00:00 +0100

Conclusions. We describe 8 cases of POWV encephalitis in Massachusetts and New Hampshire in 2013–2015. Prior to this, there had been only 2 cases of POWV encephalitis identified in Massachusetts. These cases may represent emergence of this virus in a region where its vector, I. scapularis, is known to be prevalent or may represent the emerging diagnosis of an underappreciated pathogen. We recommend testing for POWV in patients who present with encephalitis in the spring to fall in New England. (Source: Clinical Infectious Diseases)



Lyme Disease Surveillance Using Sampling Estimation: Evaluation of an Alternative Methodology in New York State

Tue, 01 Mar 2016 00:00:00 +0100

Summary In the 14‐year period from 1993 to 2006, New York State (NYS) accounted for over one‐quarter (27.1%) of all confirmed Lyme disease (LD) cases in the United States. During that time period, a nine‐county area in south‐east NYS accounted for 90.6% of the reported LD cases in the state. Based on concerns related to diminishing resources at both the state and local level and the increasing burden of traditional LD surveillance, the NYS Department of Health (DOH) sought to develop an alternative to traditional surveillance that would reduce the investigative workload while maintaining the ability to track LD trends by developing a system to estimate county‐level LD cases based on a 20% random sample of positive laboratory reports. Estimates from this system were compared to ob...

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Yamamoto new scalp acupuncture, applied kinesiology and breathing exercises for facial paralysis in a young boy caused by Lyme disease – A case report

Tue, 01 Mar 2016 00:00:00 +0100

The case study reports on the effect of pharmacological, complementary and alternative medicine including YNSA, Applied Kinesiology and respiratory exercises in a 9-year old boy with facial paralysis. (Source: Explore)



Severe symptomatic babesiosis co-infection with Lyme disease

Tue, 01 Mar 2016 00:00:00 +0100

(Source: QJM)



Molecular epidemiological surveillance to assess emergence and re-emergence of tick-borne infections in tick samples from China evaluated by nested PCRs.

Tue, 01 Mar 2016 00:00:00 +0100

Authors: Yu PF, Niu QL, Liu ZJ, Yang JF, Chen Z, Guan GQ, Liu GY, Luo JX, Yin H Abstract An investigation was performed to detect eight pathogens in ticks collected from grass tips or animals in the southern, central and northeast regions of China. DNA samples extracted from ticks were collected from ten different locations in eight provinces of China and subjected to screening for tick-borne pathogens, including Borrelia burgdorferi sensu lato, Ehrlichia spp., Rickettsia spp., Babesia/Theileria spp., Ehrlichia ruminantium, Coxiella burnetii, and Francisella tularensis, using nested PCR assays and sequencing analysis. The results indicated that Borrelia spp., Rickettsia spp., and Babesia/Theileria spp. were detected in all of the investigated provinces. Ehrlichia spp. was also foun...



Tick-Borne Illnesses.

Tue, 01 Mar 2016 00:00:00 +0100

Authors: Choi E, Pyzocha NJ, Maurer DM Abstract Tick-borne diseases are prevalent throughout the United States. These illnesses are caused by a variety of different pathogens that use ticks as vectors, including bacteria, viruses, rickettsia, and protozoa. Some of the most common illnesses caused by ticks are Lyme disease, Rocky Mountain spotted fever, babesiosis, ehrlichiosis, anaplasmosis, tularemia, Colorado tick fever, tick-borne relapsing fever, and Powassan disease. Unique skin changes, fever, and influenza-like symptoms may indicate tick-borne disease. Early diagnosis can be difficult as well as nonspecific and can resemble overtraining syndrome. Diagnosis is important to facilitate early treatment to decrease morbidity and mortality and should often be initiated before a de...



Turning #LymeintoLemonAid Thanks to My PICC Line

Tue, 01 Mar 2016 00:00:00 +0100

I was told that I was a moody teenage girl in need of antidepressants and psychotherapy, that I didn't stretch enough before and after sports so I should see a physical therapist, that I was tired because school started so early, that it was all in my head, and that I was just a clumsy person who should stop complaining. Seven years later, I was diagnosed with chronic neurologic Lyme disease and coinfections of Babesia and Bartonella. (Source: Journal of the Association for Vascular Access)

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Ageing, Drama and Creativity: Translating Research into Practice.

Sun, 28 Feb 2016 11:42:01 +0100

This article describes how the course was developed and how participants were selected; details its aims and objectives; provides an overview of the sessions and a flavour of some of the exercises that were used; and considers findings from the structured evaluation alongside written reflections from participants. PMID: 26905617 [PubMed - as supplied by publisher] (Source: Gerontology and Geriatrics Education)



Geographical differences in seroprevalence of Borrelia burgdorferi antibodies in Norway, 2011-2013

Sun, 28 Feb 2016 00:00:00 +0100

Publication date: Available online 27 February 2016 Source:Ticks and Tick-borne Diseases Author(s): Didrik F. Vestrheim, Richard A. White, Ingeborg S. Aaberge, Audun Aase Detection of specific antibodies against Borrelia burgdorferi sensu lato is a useful aid for the diagnosis of Lyme borreliosis. However, antibodies are present in the general population. The seroprevalence increase with age, and varies according to the prevalence of infected ticks. We performed a seroprevalence study of IgM and IgG antibody reactivity against B. burgdorferi sensu lato in Norway by age-groups and geography, in order to provide a reference set of seroprevalence to inform the interpretation of positive test results. We used two commercially available enzyme immuno assays (EIA) and a multiplexed bead as...



Lyme Disease 'Biofilm' Eludes Antibiotics

Thu, 25 Feb 2016 19:00:00 +0100

Germ forms slimy layer that makes it up to 1,000 times more resistant than other bacteria, researchers say Source: HealthDay Related MedlinePlus Pages: Antibiotics, Lyme Disease (Source: MedlinePlus Health News)



Lyme Disease 'Biofilm' Eludes Antibiotics: Report

Thu, 25 Feb 2016 19:00:00 +0100

Germ forms slimy layer that makes it up to 1,000 times more resistant than other bacteria, researchers say (Source: U.S. News - Health)



Phosphoenolpyruvate Phosphotransferase System Components Modulate Gene Transcription and Virulence of Borrelia burgdorferi [Molecular Pathogenesis]

Wed, 24 Feb 2016 00:00:00 +0100

We examined 12 PEP-PTS transporter component mutants by needle inoculation of mice to assess their ability to cause mouse infection. Transposon mutants with mutations in the EIIBC components (ptsG) (BB0645, thought to be involved in glucose-specific transport) were unable to cause infection in mice, while all other tested PEP-PTS mutants retained infectivity. Infectivity was partially restored in an in trans-complemented strain of the ptsG mutant. While the ptsG mutant survived normally in unfed as well as fed ticks, it was unable to cause infection in mice by tick transmission, suggesting that the function of ptsG is essential to establish infection by either needle inoculation or tick transmission. In Gram-negative organisms, the regulatory effects of the PEP-PTS are mediated by adenylat...



Tick Management Symposium to Be Held in DC in May

Tue, 23 Feb 2016 18:52:18 +0100

Annapolis, MD; February 23, 2016 – Ticks that transmit Lyme disease and other pathogens have been spreading geographically, and increased numbers of illnesses are being diagnosed. To address this issue, a symposium on Integrated Tick Management will be held May 16-17, 2016 in Washington, DC by the U.S. Centers for Disease Control and Prevention, the Entomological Society of America, the IPM Institute of North America, and the North Central IPM Center. The symposium aims to: read more (Source: ESA News)



4 ways to protect your family from mosquitoes

Tue, 23 Feb 2016 14:00:23 +0100

.Follow me at @drClaire The news about the Zika virus possibly causing microcephaly in infants has everyone talking about — and worried about — mosquitoes. It’s not just the Zika virus that can be spread by mosquitoes; these insects also spread other illnesses, such as malaria, dengue, chikungunya, yellow fever, West Nile virus, eastern equine encephalitis, and Japanese encephalitis. It should be said that most people who are bitten by mosquitoes don’t get sick with anything. But if you are living in or traveling to an area where these illnesses are prevalent, it’s important to know the four best ways to protect yourself and your family: Choose your clothes wisely. Lightweight long sleeves and long pants are your best bet; spraying clothing with insect repellent may help even mo...



Tick management symposium to be held in Washington, DC in May

Tue, 23 Feb 2016 05:00:00 +0100

(Entomological Society of America) Ticks that transmit Lyme disease and other pathogens have been spreading geographically, and increased numbers of illnesses are being diagnosed. To address this issue, a symposium on Integrated Tick Management will be held May 16-17, 2016 in Washington, DC by the US Centers for Disease Control and Prevention, the Entomological Society of America, the IPM Institute of North America, and the North Central IPM Center. (Source: EurekAlert! - Infectious and Emerging Diseases)



Genome reveals insights into tick that spreads Lyme disease

Tue, 23 Feb 2016 00:00:00 +0100

Researchers deciphered the genome of the blacklegged tick, which causes several diseases, including Lyme disease. The resource can aid development of new ways to control ticks. (Source: NIH Research Matters from the National Institutes of Health (NIH))

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Empirical third-generation cephalosporin therapy for adults with community-onset Enterobacteriaceae bacteraemia: impact of revised CLSI breakpoints

Tue, 23 Feb 2016 00:00:00 +0100

Bacteraemia is a life-threatening condition associated with high morbidity and mortality [1] and is typically complicated by severe sepsis or septic shock [2]. Third-generation cephalosporins (3GCs), such as cefotaxime (CTX) and ceftriaxone (CRO), have remarkable potency against all Enterobacteriaceae and have been established as an appropriate parenteral treatment of various community-onset infections caused by susceptible organisms, such as complicated urinary tract infections, lower respiratory tract infections, bacterial meningitis, bacteraemia, connective tissue infections, pelvic inflammatory disease, intra-abdominal infections and Lyme disease [3,4]. (Source: International Journal of Antimicrobial Agents)



Probable doxycycline-induced acute pancreatitis.

Mon, 22 Feb 2016 21:17:04 +0100

CONCLUSION: A man developed AP three days after starting therapy with oral doxycycline, and the association between drug and reaction was determined to be probable. His case appears to be the third of doxycycline-associated AP, although tigecycline, tetracycline, and minocycline have also been implicated as causes of AP. PMID: 26896500 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)



Efficacy of sarolaner in the prevention of Borrelia burgdorferi and Anaplasma phagocytophilum transmission from infected Ixodes scapularis to dogs

Sun, 21 Feb 2016 00:00:00 +0100

Publication date: Available online 20 February 2016 Source:Veterinary Parasitology Author(s): Nicole A. Honsberger, Robert H. Six, Thomas J. Heinz, Angela Weber, Sean P. Mahabir, Thomas C. Berg The efficacy of sarolaner (Simparica™, Zoetis) to prevent transmission primarily of Borrelia burgdorferi and secondarily of Anaplasma phagocytophilum from infected wild-caught Ixodes scapularis to dogs was evaluated in a placebo-controlled laboratory study. Twenty-four purpose-bred laboratory Beagles seronegative for B. burgdorferi and A. phagocytophilum antibodies were allocated randomly to one of three treatment groups: placebo administered orally on Days 0 and 7, or sarolaner at 2mg/kg administered orally on Day 0 (28 days prior to tick infestation) or on Day 7 (21 days prior to tick in...



Larvae of Ixodes ricinus transmit Borrelia afzelii and B. miyamotoi to vertebrate hosts

Sat, 20 Feb 2016 00:00:00 +0100

Lyme borreliosis is the most common tick-borne human disease and is caused by Borrelia burgdorferi sensu lato (s.l.). Borrelia miyamotoi, a relapsing fever spirochaete, is transmitted transovarially, whereas this... (Source: Parasites and Vectors)



Lyme Disease in Hispanics, United States, 2000-2013.

Fri, 19 Feb 2016 22:56:03 +0100

Authors: Nelson CA, Starr JA, Kugeler KJ, Mead PS Abstract Hispanics comprise a growing portion of the US population and might have distinct risk factors for tickborne diseases. During 2000-2013, a total of 5,473 Lyme disease cases were reported among Hispanics through national surveillance. Hispanics were more likely than non-Hispanics to have signs of disseminated infection and onset during fall months. PMID: 26889721 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)

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IV Therapy “Cocktail” For a Cancer Patient

Fri, 19 Feb 2016 17:40:19 +0100

Today, I want to talk to you about my patient D.B. A key treatment I offer at the Sears Institute for Anti-Aging Medicine turned her life around and boosted her chances of recovering from cancer. D.B had been a vivacious 47-year-old woman, who’d always led a healthy life. For years, she’d watched her diet carefully and exercised regularly. But then she was diagnosed with endometrial cancer. This is cancer of the inner lining of the uterus. When she came to my clinic, she’d already undergone a hysterectomy and chemotherapy. Unsurprisingly, she felt terrible. She was pale. She felt lethargic and she was experiencing severe mental fog. Every moment of her life had become a struggle. It was clear right away that D.B. was deficient in several important nutrients. It was also clear her im...



Lyme: The Infectious Disease Equivalent of Cancer, Says Top Duke Oncologist

Fri, 19 Feb 2016 16:50:57 +0100

Last week, I mentioned the case of Dr. Neil Spector, whose long-undiagnosed Lyme Disease resulted in irreversible heart failure and ultimately, a heart transplant. Dr. Spector, author of Gone in a Heartbeat: A Physician's Search for True Healing, is the Sandra Coates Associate Professor of Medicine and Associate Professor of Pharmacology and Cancer Biology at Duke University School of Medicine. As the Director of Developmental Therapeutics at the Duke Cancer Institute, he's a leader in applying translational research to the clinical development of molecularly targeted personalized cancer therapies. Here, Dr. Spector shares his story, explains what Lyme and cancer have in common (hint: a LOT), and encourages us with his vision for the future. Like so many of us, your Lyme was missed by mu...



New Bacterial Species Causes Lyme DiseaseNew Bacterial Species Causes Lyme Disease

Thu, 18 Feb 2016 17:24:36 +0100

U.S. researchers say they have discovered a new bacterial species that causes Lyme disease in humans. Reuters Health Information (Source: Medscape Pathology Headlines)



[PCR-based detection of pathogens in clinical rheumatology].

Thu, 18 Feb 2016 00:00:00 +0100

Authors: Ehrenstein B, Reischl U Abstract In the differential diagnostics of autoimmune-mediated rheumatic diseases, rheumatologists often have to consider infections (e. g. Lyme arthritis) or reactive diseases (e. g. reactive arthritis after urogenital bacterial infections). Furthermore, infections with an atypical presentation or caused by atypical pathogens (opportunistic infections) can complicate the immunosuppressive therapy of autoimmune diseases. For this purpose not only conventional microbiological culture methods but also PCR-based methods are increasingly being applied for the direct detection of pathogens in clinical specimens. The aim of this overview is to present commonly used PCR methods in the clinical practice of rheumatology and to describe their benefits an...



New Cause for Lyme Disease Complicates Already Murky Diagnosis

Tue, 16 Feb 2016 15:00:00 +0100

Scientists claim a novel bacterium causes some different symptoms, adding to the body of research showing the complexity of the disease  -- Read more on ScientificAmerican.com (Source: Scientific American)

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A New Culprit in Lyme Disease

Mon, 15 Feb 2016 21:15:38 +0100

Researchers have discovered a second bacterium that may cause the condition. (Source: NYT Health)



New Gene Discovery Could Lead To Earlier Lyme Test And Diagnosis

Mon, 15 Feb 2016 05:05:00 +0100

An experimental new test holds great promise for diagnosing Lyme disease soon after infection, well before current tests are able to detect infection. (Source: Forbes.com Healthcare News)



Sexual transmission of Lyme disease: challenging the tickborne disease paradigm.

Sun, 14 Feb 2016 16:32:09 +0100

Authors: Stricker RB, Middelveen MJ Abstract Lyme disease caused by the spirochete Borrelia burgdorferi has become a major worldwide epidemic. In this article, we explore the clinical, epidemiological and experimental evidence for sexual transmission of Lyme disease in animal models and humans. Although the likelihood of sexual transmission of the Lyme spirochete remains speculative, the possibility of Lyme disease transmission via intimate human contact merits further study. PMID: 26489537 [PubMed - in process] (Source: Expert Review of Anti-Infective Therapy)



Big data and patient-powered research aim to solve complex diseases

Sat, 13 Feb 2016 05:00:00 +0100

(LymeDisease.org) Big data and patient-driven research networks have the power to accelerate our understanding of some of today's most complex diseases. Lorraine Johnson, CEO of Lymedisease.org, will give a presentation at the AAAS meeting on Feb. 13 on 'Big Data and Patient Powered Networks.' She will discuss how MyLymeData, the first and only national patient-powered research project on chronic Lyme disease, is being embraced by thousands of patients, anxious for answers that will improve their lives. (Source: EurekAlert! - Infectious and Emerging Diseases)



Vector competence of the blacklegged tick, Ixodes scapularis, for the recently recognized Lyme borreliosis spirochete Borrelia mayonii

Sat, 13 Feb 2016 00:00:00 +0100

Publication date: Available online 12 February 2016 Source:Ticks and Tick-borne Diseases Author(s): Marc C. Dolan, Andrias Hojgaard, J. Charles Hoxmeier, Adam J. Replogle, Laurel B. Respicio-Kingry, Christopher Sexton, Martin A. Williams, Bobbi S. Pritt, Martin E. Schriefer, Lars Eisen A novel species within the Borrelia burgdorferi sensu lato complex, provisionally named Borrelia mayonii, was recently found to be associated with Lyme borreliosis in the Upper Midwest of the United States. Moreover, B. mayonii was detected from host-seeking Ixodes scapularis, the primary vector of Borrelia burgdorferi sensu stricto in the eastern United States. We therefore conducted a study to confirm the experimental vector competence of I. scapularis for B. mayonii (strain MN14-1420), using c...

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New experimental test detects signs of Lyme disease near time of infection

Fri, 12 Feb 2016 21:39:19 +0100

An experimental method developed by researchers appears capable of detecting the stealthy culprit Lyme bacteria at the earliest time of infection, when currently available tests are often still negative. (Source: ScienceDaily Headlines)



Gene signature could lead to a new way of diagnosing Lyme Disease

Fri, 12 Feb 2016 14:37:02 +0100

Researchers may have found a new way to diagnose Lyme disease, based on a distinctive gene “signature” they discovered in white blood cells of patients infected with the tick-borne bacteria. (Source: ScienceDaily Headlines)



Gene Discovery Could Point to New Lyme Disease Test: Study

Fri, 12 Feb 2016 14:00:00 +0100

Researchers say patients have tell-tale genetic signatures, even after taking antibiotics (Source: U.S. News - Health)



New experimental test detects signs of Lyme disease near time of infection

Fri, 12 Feb 2016 05:00:00 +0100

(National Institute of Standards and Technology (NIST)) Team from NIST and Johns Hopkins suggests the novel approach might also be useful for early detection of other elusive bacterial infections. (Source: EurekAlert! - Infectious and Emerging Diseases)

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Gene signature could lead to a new way of diagnosing Lyme

Fri, 12 Feb 2016 05:00:00 +0100

(University of California - San Francisco) Researchers at UC San Francisco and Johns Hopkins may have found a new way to diagnose Lyme disease, based on a distinctive gene 'signature' they discovered in white blood cells of patients infected with the tick-borne bacteria. (Source: EurekAlert! - Infectious and Emerging Diseases)






Borrelia mayonii is new cause of Lyme disease variant

Thu, 11 Feb 2016 14:52:06 +0100

A new species of Borrelia has been linked to a variant of Lyme disease with symptoms that differ somewhat from typical Lyme borreliosis. Of 100,545 routine clinical specimens tested at the... (Source: Rheumatology News)



How Lyme disease is spread is revealed by unraveling tick's DNA

Thu, 11 Feb 2016 06:03:54 +0100

Scientists from Purdue University in Indiana found the genome of Lyme disease-spreading ticks is 'far more similar to mammals than insects' - and that the ticks' saliva allows them to feed off a host for days. (Source: the Mail online | Health)



Medical Evidence Supports Denial Of LTD Claim, Federal Judge Determines

Wed, 10 Feb 2016 05:07:20 +0100

PITTSBURGH - Because there is significant medical evidence supporting a disability plan's denial of a claim for long-term disability (LTD) benefits related to Lyme disease, a Pennsylvania federal judge on Feb. 1 denied the claimant's motion for summary judgment and granted the plan's motion for summary judgment (Elizabeth L. Ryan v. PNC Financial Services Group Inc., et al., No. 14-1048, W.D. Pa.; 2016 U.S. Dist. LEXIS 11518). (Source: LexisNexis® Mealey's™ Disability Insurance Legal News)



Tick tock -- sequencing the tick genome could help defuse the Lyme disease time bomb

Wed, 10 Feb 2016 05:00:00 +0100

(Swiss Institute of Bioinformatics) After a decade-long research effort the genome of the deer tick has been sequenced by an international team of scientists, including researchers from the SIB Swiss Institute of Bioinformatics. Studying the tick genome sheds light on how ticks function and will help to develop novel tick control programs by interfering with the processes of disease transmission. (Source: EurekAlert! - Biology)

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Lyme Disease in Hispanics, United States, 2000–2013

Wed, 10 Feb 2016 05:00:00 +0100

C. Nelson et al. (Source: Emerging Infectious Diseases Journal)



Unilateral sequential papillophlebitis and central retinal artery occlusion in a young healthy patient

Wed, 10 Feb 2016 00:00:00 +0100

Gülizar Demirok, Mehmet Fatih Kocamaz, Yasemin Topalak, Ahmet Sengün, Berati HasanreisogluIndian Journal of Ophthalmology 2015 63(12):921-924A 23-year-old girl presented to the clinic with metamorphopsia and photopsia in her left eye. After detailed ophthalmic examination, central retinal vein occlusion with optic disc edema was detected in that eye. Three days after diagnosis, the patient returned to our clinic with visual acuity decrease. Central retinal artery occlusion sparing cilioretinal artery was detected. All the laboratory tests were normal except for heterozygous methylenetetrahydrofolate reductase mutation (A1298C genotypes) and an indefinite Lyme disease seropositivity. Symptoms and visual disturbance recovered without any further treatment other than acetylsalic...



Eradication of Biofilm-Like Microcolony Structures of Borrelia burgdorferi by Daunomycin and Daptomycin but not Mitomycin C in Combination with Doxycycline and Cefuroxime

Wed, 10 Feb 2016 00:00:00 +0100

Jie Feng, Megan Weitner, Wanliang Shi, Shuo Zhang, Ying Zhang (Source: Frontiers in Microbiology)



Mayo Clinic Minute: Lyme Disease Discovery

Wed, 10 Feb 2016 00:00:00 +0100

Mayo Clinic researchers have discovered a new Lyme disease-causing organism that is capable of creating more intense symptoms. In this Mayo Clinic Minute, Jeff Olsen speaks with Dr. Bobbi Pritt, director of the Clinical Parasitology Laboratory at Mayo Clinic, about the new findings. Watch the Mayo Clinic Minute https://www.youtube.com/watch?v=r7TxQs4FIVs&feature=youtu.be Journalists: Broadcast quality video is available [...] (Source: News from Mayo Clinic)



New Bacteria That Causes Lyme Disease Discovered

Tue, 09 Feb 2016 23:33:59 +0100

Researchers from the Mayo Clinic and the CDC made the discovery. (Source: ABC News: Health)

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New species of bacteria causes Lyme disease in humans, scientists warn

Tue, 09 Feb 2016 22:52:50 +0100

The Centers for Disease Control and Prevention revealed a new bacteria also causes Lyme disease - with more severe symptoms, such as nausea and rash, than a previously found bacteria. (Source: the Mail online | Health)



Taking Concussions Head-On: Part II

Tue, 09 Feb 2016 20:16:58 +0100

Recognizing the Breadth of the Problem and the Search for Answers Previously, I discussed the serious issue of concussions in sports - at all levels - and some of the efforts being pursued to combat it. Much is being done, but one simple and effective path bears further exploration. There may be reason to believe that the secret to diagnosing a concussion could reside in our saliva, offering for the first time an avenue to quickly and accurately provide a definitive diagnosis. Developing a Spit Test Long regarded as the sole domain of the dentist, the medical community in recent years has begun to recognize the mouth as a vital gateway to identifying and evaluating overall body wellness. One initiative helping to change this perception is the emergence of salivary diagnostics. Saliva, it...



New Lyme Disease Bacteria Discovered: CDC

Tue, 09 Feb 2016 18:16:38 +0100

Infection may trigger nausea, vomiting and a more widespread rash, officials say (Source: WebMD Health)



Scientists Discover New Bacteria Responsible For Lyme Disease

Tue, 09 Feb 2016 17:26:57 +0100

ATLANTA (Reuters) - Researchers have discovered a new bacteria that causes Lyme disease in humans, a U.S. health agency said Monday. The Centers for Disease Control and Prevention, working with the Mayo Clinic and health officials from Minnesota, Wisconsin and North Dakota, discovered the new bacteria, called Borrelia mayonii, the CDC said in a statement. Previously, only one bacteria, Borrelia burgdorferi, was believed to cause human Lyme disease, which is transmitted through bites from by the blacklegged "deer" tick, the CDC statement said. The new bacteria has so far only been detected in the upper Midwest region of the United States, the CDC said. Researchers discovered Borrelia mayonii after studying blood samples of patients in Minnesota, Wisconsin, and North Dakota who were suspecte...



New Lyme Disease Bacteria Discovered in Upper Midwest: CDC

Tue, 09 Feb 2016 17:00:00 +0100

Infection may trigger nausea, vomiting and a more widespread rash, officials say Source: HealthDay Related MedlinePlus Pages: Lyme Disease, Tick Bites (Source: MedlinePlus Health News)

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Medical News Today: New bacteria discovered that cause Lyme disease

Tue, 09 Feb 2016 15:00:00 +0100

Scientists have found new bacteria that cause Lyme disease. They produce symptoms similar to those of the known bacteria, but they also cause nausea, vomiting and diffuse rashes. (Source: Health News from Medical News Today)



Scientists confirm second, more intense form of Lyme disease

Tue, 09 Feb 2016 14:59:39 +0100

Stephen FellerATLANTA, Feb. 9 (UPI) -- The CDC and Mayo Clinic confirmed a second species of bacteria causing Lyme disease in the upper Midwest area of the United States. (Source: Health News - UPI.com)



New Lyme Disease Bacteria Discovered in Upper Midwest: CDC

Tue, 09 Feb 2016 12:02:25 +0100

TUESDAY, Feb. 9, 2016 -- A new Lyme disease-causing bacteria has been identified in the United States, and it may bring even worse symptoms, health officials said. Borrelia burgdorferi was the only bacteria species believed to cause Lyme disease in... (Source: Drugs.com - Daily MedNews)



Scientists Found A New Bacteria Causing Lyme Disease: Borrelia Mayonii

Tue, 09 Feb 2016 12:00:00 +0100

There’s a new Borrelia bacterium on the block, joining its cousin in causing Lyme disease. B. mayonii has recently been identified as a new cause of Lyme in the Midwest. (Source: Forbes.com Healthcare News)



Studying Tick Biology With Lyme Prevention in Mind

Tue, 09 Feb 2016 09:02:35 +0100

TUESDAY, Feb. 9, 2016 -- Scientists who sequenced the genome, or genetic composition, of the Lyme disease-transmitting deer tick hope the achievement will lead to new ways to control the blood-sucking parasites. The decade-long effort involved an... (Source: Drugs.com - Daily MedNews)

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Tick genome reveals inner workings of a resilient blood-guzzler

Tue, 09 Feb 2016 05:00:00 +0100

(Purdue University) An international team of scientists led by Purdue University has sequenced the genome of the tick that transmits Lyme disease, the most common vector-borne illness in North America. (Source: EurekAlert! - Infectious and Emerging Diseases)



Lyme disease just got nastier

Tue, 09 Feb 2016 03:57:23 +0100

Until now, scientists thought only one species of bacteria was responsible for the tick-borne Lyme disease (Source: Health News: CBSNews.com)



Pilot Cross-Sectional Study of Three Zoonoses (Lyme Disease, Tularaemia, Leptospirosis) among Healthy Blood Donors in Eastern Slovakia.

Tue, 09 Feb 2016 01:52:02 +0100

CONCLUSIONS: ELPAGA seroprevalence for TUL was significantly higher in blood donors working in the agricultural area in the direct contact with hay, straw, manure, and agricultural land. Our outputs determine tick bite as a significant risk factor for LB. The study confirms the explosion of tick-borne diseases in the healthy population of people. The exposure risk for leptospirosis seems to be minimal. PMID: 26851418 [PubMed - as supplied by publisher] (Source: Central European Journal of Public Health)



New Bacteria Species that Causes Lyme Disease Discovered (FREE)

Tue, 09 Feb 2016 00:00:00 +0100

By Kelly Young Edited by Jaye Elizabeth Hefner, MD Scientists report the discovery of a new species of bacteria (Borrelia mayonii) in the upper Midwest of the U.S. that causes a unique presentation of Lyme disease. Their findings appear in the Lancet Infectious Diseases.Researchers screened … (Source: Physician's First Watch current issue)



Changes in the Proteome of Langat-Infected Ixodes scapularis ISE6 Cells: Metabolic Pathways Associated with Flavivirus Infection

Tue, 09 Feb 2016 00:00:00 +0100

Conclusions/Significance Proteomic analyses revealed ISE6 proteins that were differentially expressed at the peak of LGTV replication. Proteins with increased expression following infection were associated with cellular metabolic pathways and glutaminolysis. In vitro assays using small molecules implicate malate dehydrogenase (MDH2), the citrate cycle, cellular acetylation, and electron transport chain processes in viral replication. Proteins were identified that may be required for TBF infection of ISE6 cells. These proteins are candidates for functional studies and targets for the development of transmission-blocking vaccines and drugs. (Source: PLoS Neglected Tropical Diseases)

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