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MedWorm: Rubella



MedWorm.com provides a medical RSS filtering service. Over 7000 RSS medical sources are combined and output via different filters. This feed contains the latest news and research in the Rubella category.



Last Build Date: Tue, 29 Mar 2016 12:11:37 +0100

 



Real time PCR for the diagnosis of Rubella Virus, Herpes Simplex virus-1 and Toxoplasma gondii in patients with congenital cataract

Tue, 29 Mar 2016 09:23:35 +0100

Background: Congenital cataract is most serious type of cataract and has the potential for inhibiting early visual development. Intrauterine infections with Rubella virus (RV), Herpes simplex virus-1 (HSV) and Toxoplasma gondii play an important role in the development of congenital cataract. The aim of present study was to know the contribution of RV, HSV-1 and T.gondii towards congenital cataract in children attending a tertiary care hospital in North India. (Source: International Journal of Infectious Diseases)

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Robert De Niro Pulls Controversial Anti-Vaccination Documentary From Tribeca Film Festival

Sun, 27 Mar 2016 00:38:53 +0100

A controversial anti-vaccination documentary has been pulled from the Tribeca Film Festival lineup after it was met with fierce criticism, festival co-founder Robert De Niro announced on Saturday. De Niro, who had just a day earlier defended showing "Vaxxed: From Cover-Up to Catastrophe," said in a statement "we do not believe it contributes to or furthers the discussion I had hoped for." The actor and the festival were hit with an onslaught of criticism for showing the documentary by the disgraced anti-vax doctor Andrew Wakefield. The documentary claims that the U.S. Centers for Disease Control and Prevention concocted a conspiracy to cover up the "true" reason for America’s rising autism diagnosis rates: vaccines. Extensive research, including studies by the World Health Organ...



Laboratory confirmation of rubella infection in suspected measles cases

Sat, 26 Mar 2016 23:00:00 +0100

This article is protected by copyright. All rights reserved (Source: Journal of Medical Virology)



Andrew Wakefield, Disgraced Anti-Vax Doctor, Returns With A Documentary At Tribeca Film Fest

Fri, 25 Mar 2016 18:04:09 +0100

Andrew Wakefield is back in the news, thanks to a new, controversial documentary set to premiere at the upcoming Tribeca Film Festival in New York. The film, directed by Wakefield himself, claims that the U.S. Centers for Disease Control and Prevention orchestrated a conspiracy to cover up the "true" reason for America's rising autism diagnosis rates: vaccines.  This is a widely and soundly discredited assertion. Studies from the independent, non-profit Institute of Medicine, the World Health Organization and the CDC have all found that there is no link between receiving vaccines and developing autism spectrum disorder. Instead, what these studies demonstrate is that vaccines are overwhelmingly safe, with very rare cases of side effects, and that they protect children f...



What are some of the myths – and facts – about vaccination?

Thu, 24 Mar 2016 00:00:00 +0100

What are some of the myths—and facts—about vaccination? (Source: WHO Feature Stories)



Anti-Vaxxers Are Officially To Blame For The Rise In 2 Preventable Diseases

Wed, 23 Mar 2016 19:48:40 +0100

The recent rise in the U.S. of vaccine-preventable diseases has been largely blamed on those who refuse to vaccinate their children. Previous analyses have linked anti-vaxxers to certain outbreaks -- like last year's Disneyland measles outbreak -- but there was still some controversy over the connection.  Now a new review funded by the National Institutes of Health has found a correlation between vaccine refusal and the rise of measles and whooping cough (also known as pertussis), two common vaccine-preventable conditions.  Researchers at Emory University and Johns Hopkins Bloomberg School of Health reviewed reported case data in conjunction with previously published studies to better understand the relationship between vaccine refusal, delay or exemption and the f...

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Effect of socioeconomic deprivation on uptake of measles, mumps and rubella vaccination in Liverpool, UK over 16 years: a longitudinal ecological study

Tue, 22 Mar 2016 13:34:21 +0100

Research Articles D. HUNGERFORD, P. MACPHERSON, S. FARMER, S. GHEBREHEWET, D. SEDDON, R. VIVANCOS, A. KEENAN, Epidemiology & Infection, Volume 144 Issue 06, pp 1201-1211Abstract (Source: Epidemiology and Infection)



Impact of State Public Health Spending on Disease Incidence in the United States from 1980 to 2009

Mon, 21 Mar 2016 00:00:00 +0100

ConclusionOur analysis indicates that there is evidence of a significant, negative relationship between a state's public health spending and the incidence of two VPDs, mumps and rubella, in the United States. (Source: Health Services Research)



A theoretical estimate of the risk of microcephaly during pregnancy with Zika virus infection

Fri, 18 Mar 2016 00:00:00 +0100

Conclusions The time interval between peaks of reported dengue-like illness and microcephaly was consistent with cause-outcome relationship. Our modeling framework predicts that the incidence of microcephaly is expected to steadily decline in early 2016, Brazil. (Source: Epidemics)



Microsynteny and phylogenetic analysis of tandemly organised miRNA families across five members of Brassicaceae reveals complex retention and loss history

Wed, 16 Mar 2016 00:00:00 +0100

Publication date: June 2016 Source:Plant Science, Volume 247 Author(s): Priyanka Rathore, R. Geeta, Sandip Das Plant genomes are characterized by the presence of large miRNA gene families which are few in number. The expansion of miRNA families is thought to be driven by gene and genome duplication. Some members of these miRNA gene families are tandemly arranged and their analysis is of interest because such organisation may indicate origin through tandem duplication and also to investigate whether some such tandem clusters have similar expression patterns, and whether these are regulated through a common set of cis-regulatory elements (eg. promoters and enhancers). As a first step, we undertake a comprehensive study using micro-synteny analyses of tandemly organised miRNA families ac...

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Efficacy of intralesional immunotherapy for the treatment of warts: A review of the literature

Tue, 15 Mar 2016 00:00:00 +0100

ABSTRACT Warts are common epidermal growths caused by human papillomavirus that often cause significant discomfort and embarrassment. Current treatment options include topical therapies, cryotherapy, laser vaporization, and surgical excision. Many of these options are destructive and may result in scarring, while less aggressive approaches can lead to lesion recurrence. Additionally, these local modalities are not practical for patients with a large number of warts. Systemic approaches such as immunotherapy have demonstrated success in treating multiple lesions by combining a targeted approach with upregulation of the host immune system. An extensive literature review was performed to evaluate the various vaccine antigens that have been used intralesionally to treat cutaneous and anogenita...



MMR vaccination call following recent measles cases

Mon, 14 Mar 2016 00:00:00 +0100

Increase in measles cases since February prompts measles mumps and rubella (MMR) vaccination call. (Source: NHS Networks)



Monitoring the process of measles elimination by serosurveillance data: The Apulian 2012 study.

Mon, 14 Mar 2016 00:00:00 +0100

Authors: Tafuri S, Gallone MS, Gallone MF, Pappagallo MT, Larocca A, Germinario C Abstract In 2003 Italy adopted the National Plan for Measles and Congenital Rubella Elimination, but some outbreaks of measles are still occurring, as the target coverage rate (≥95%) for new-borns has currently not been achieved. In order to support the monitoring of the measles elimination programme, the authors carried out a survey about the seroprevalence of measles among Apulia young adults. The study was carried out from May 2011 to June 2012 among blood donors of the Department of Transfusion Medicine of Policlinico General Hospital in Bari. Subjects were enrolled by a convenience sampling. For each enrolled patient we collected a 5mL serum sample. Collected sera were tested by chemiluminescen...



Microsynteny and phylogenetic analysis of tandemly organized miRNA families across five members of Brassicaceae reveals complex retention and loss history

Fri, 11 Mar 2016 00:00:00 +0100

Publication date: Available online 10 March 2016 Source:Plant Science Author(s): Priyanka Rathore, R. Geeta, Sandip Das Plant genomes are characterized by the presence of large miRNA gene families which are few in number. The expansion of miRNA families is thought to be driven by gene and genome duplication. Some members of these miRNA gene families are tandemly arranged and their analysis is of interest because such organisation may indicate origin through tandem duplication and also to investigate whether some such tandem clusters have similar expression patterns, and whether these are regulated through a common set of cis-regulatory elements (eg. promoters and enhancers). As a first step, we undertake a comprehensive study using micro-synteny analyses of tandemly organized miRNA fa...



Waning immunity against mumps in vaccinated young adults, France 2013

Thu, 10 Mar 2016 00:00:00 +0100

In 2013, 15 clusters of mumps were notified in France; 72% (82/114) of the cases had been vaccinated twice with measles-mumps-rubella vaccine. To determine whether the risk of mumps increased with time since the last vaccination, we conducted a case-control study among clusters in universities and military barracks. A confirmed case had an inflammation of a salivary gland plus laboratory confirmation in 2013. A probable case presented with inflammation of a salivary gland in 2013 either lasting for?>?2 days or with epidemiological link to a confirmed case. Controls had no mumps symptoms and attended the same university course, student party or military barracks. We collected clinical and vaccination data via web questionnaire and medical records. We calculated adjusted odds ratios (aOR)...

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Waning immunity against mumps in vaccinated young adults, France 2013.

Thu, 10 Mar 2016 00:00:00 +0100

Authors: Vygen S, Fischer A, Meurice L, Mounchetrou Njoya I, Gregoris M, Ndiaye B, Ghenassia A, Poujol I, Stahl JP, Antona D, Le Strat Y, Levy-Bruhl D, Rolland P Abstract In 2013, 15 clusters of mumps were notified in France; 72% (82/114) of the cases had been vaccinated twice with measles-mumps-rubella vaccine. To determine whether the risk of mumps increased with time since the last vaccination, we conducted a case-control study among clusters in universities and military barracks. A confirmed case had an inflammation of a salivary gland plus laboratory confirmation in 2013. A probable case presented with inflammation of a salivary gland in 2013 either lasting for > 2 days or with epidemiological link to a confirmed case. Controls had no mumps symptoms and attended the sam...



Genotypes of rubella virus and the epidemiology of rubella infections in the Democratic Republic of the Congo, 2004–2013

Wed, 09 Mar 2016 01:19:05 +0100

ConclusionThis report provides the first information on the genotypes of rubella virus circulating in the DRC. These data contribute to a better understanding of rubella burden and the dynamics of rubella virus circulation in Africa. Efforts to establish rubella surveillance in the DRC are needed to support rubella elimination in Africa. This article is protected by copyright. All rights reserved (Source: Journal of Medical Virology)



Tip-localized receptors control pollen tube growth and LURE sensing in Arabidopsis

Wed, 09 Mar 2016 00:00:00 +0100

Authors: Hidenori Takeuchi & Tetsuya Higashiyama Directional control of tip-growing cells is essential for proper tissue organization and cell-to-cell communication in animals and plants. In the sexual reproduction of flowering plants, the tip growth of the male gametophyte, the pollen tube, is precisely guided by female cues to achieve fertilization. Several female-secreted peptides have recently been identified as species-specific attractants that directly control the direction of pollen tube growth. However, the method by which pollen tubes precisely and promptly respond to the guidance signal from their own species is unknown. Here we show that tip-localized pollen-specific receptor-like kinase 6 (PRK6) with an extracellular leucine-rich repeat domain is an essential receptor ...



Varicella zoster virus related deaths and hospitalizations in Brazil before the introduction of universal vaccination with the tetraviral vaccine.

Tue, 08 Mar 2016 00:00:00 +0100

CONCLUSIONS: Varicella is associated, in the pre-vaccine period, to significant morbidity and mortality in Brazil. The universal vaccination program is expected to decrease the disease burden from varicella. PMID: 26969400 [PubMed - as supplied by publisher] (Source: Jornal de Pediatria)



Parental Vaccine Hesitancy in Quebec (Canada)

Mon, 07 Mar 2016 16:00:05 +0100

This study aims to contribute to the ongoing reflections on tools and indicators of vaccine hesitancy by providing results of a survey on knowledge, attitudes and beliefs (KAB) of parents in Quebec (Canada). We have compared KAB of parents according to: 1) self-reported vaccination status of their child and 2) hesitation during the vaccination decision. Methods Data were collected through the 2014 Quebec study on vaccination against seasonal influenza and pneumococcal infections, a biennial repeated cross-sectional study in the province of Quebec, Canada. This paper presents the results pertaining to parents’ KAB about vaccination; the full report can be found elsewhere.15 Data were collected through a computer-assisted telephone interview survey conducted between March 18 and April 2...

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Hypothetical Pathogenesis of Rubella Induced Type 1 Diabetes

Mon, 07 Mar 2016 00:00:00 +0100

A hypothesis is advanced to explain how, in individuals with congenital rubella syndrome, the rubella virus produces what is commonly considered to be an autoimmune disease process, Type 1 diabetes. (Source: Medical Hypotheses)



Progress Toward Measles Elimination - Nepal, 2007-2014.

Sat, 05 Mar 2016 15:17:02 +0100

This report updates a previous report (4) and summarizes progress toward measles elimination in Nepal during 2007-2014. During 2007-2014, estimated coverage with the first MCV dose (MCV1) increased from 81% to 88%. Approximately 3.9 and 9.7 million children were vaccinated in SIAs conducted in 2008 and 2014, respectively (1). Reported suspected measles incidence declined by 13% during 2007-2014, from 54 to 47 cases per 1 million population. However, in 2014, 81% of districts did not meet the measles case-based surveillance performance indicator target of ≥2 discarded non-measles cases(¶) per 100,000 population per year. To achieve and maintain measles elimination, additional measures are needed to strengthen routine immunization services to increase coverage with MCV1 and a recently int...



Measles Virus Neutralizing Antibody Response, Cell-Mediated Immunity, and Immunoglobulin G Antibody Avidity Before and After Receipt of a Third Dose of Measles, Mumps, and Rubella Vaccine in Young Adults

Sat, 05 Mar 2016 00:00:00 +0100

Conclusions. Most subjects were seropositive before MMR3 receipt, and very few had a secondary immune response after MMR3 receipt. Similarly, CMI and avidity analyses showed minimal qualitative improvements in immune response after MMR3 receipt. We did not find compelling data to support a routine third dose of MMR vaccine. (Source: The Journal of Infectious Diseases)



Ten-day Measles, 3-day Measles, German Measles, and More

Fri, 04 Mar 2016 13:17:21 +0100

Rubeola, roseola, rubella -- oh my! See what you know about traditional lay terms for these diseases and how they are similar and different. (Source: ConsultantLive)



Severity of mumps disease is related to MMR vaccination status and viral shedding.

Fri, 04 Mar 2016 00:00:00 +0100

CONCLUSIONS: MMR vaccination was associated with less severe disease among mumps patients. Systemic spread of virus was associated with more severe disease. The elevated salivary viral loads in patients with systemic mumps disease suggest that these patients pose a higher risk for mumps virus transmission. Our study contributes to the understanding of mumps virus pathogenesis and shows the protective effect of MMR vaccination on severity of disease. PMID: 26954106 [PubMed - as supplied by publisher] (Source: Vaccine)

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Ministerial conference concludes with pledge to improve access to vaccines

Tue, 01 Mar 2016 08:28:29 +0100

Photo courtesy of Translieu/David Mugithi29 February 2016 – At a landmark Ministerial Conference on Immunization in Africa held from 24 to 25 February, in Addis Ababa, Ethiopia, African Ministers of Health, Finance, Education, Social Affairs and local governments signed a declaration to promote the use of vaccines to protect people of all ages against vaccine-preventable diseases and to close the immunization gap by 2020. One in 5 African children still do not receive all of the most basic vaccines they need against three critical diseases — measles, rubella and neonatal tetanus. Read more  Declaration on universal access to immunization as a cornerstone for health and development in Africa Ministerial Conference on Immunization in Africa, Addis Ababa, 24–25 February 2016 Read mo...



Universal varicella vaccine immunization in Japan.

Tue, 01 Mar 2016 00:00:00 +0100

Authors: Yoshikawa T, Kawamura Y, Ohashi M Abstract In 1974, Japanese scientists developed a live attenuated varicella vaccine based on the Oka strain. The efficacy of the vaccine for the prevention of varicella has been primarily demonstrated in studies conducted in the United States following the adoption of universal immunization using the Oka strain varicella vaccine in 1996. Although the vaccine was developed by Japanese scientists, until recently, the vaccine has been administered on a voluntary basis in Japan resulting in a vaccine coverage rate of approximately 40%. Therefore, Japan initiated universal immunization using the Oka strain varicella vaccine in November 2014. Given the transition from voluntary to universal immunization in Japan, it will also be important to mon...



Zika fever and congenital Zika syndrome: an unexpected emerging arboviral disease?

Mon, 29 Feb 2016 00:00:00 +0100

Unlike its mosquito-borne relatives which can cause severe human diseases, including dengue, West Nile, and Japanese encephalitis viruses, Zika virus (ZIKV) has emerged from obscurity by its association with a suspected “congenital Zika syndrome”, while causing asymptomatic or mild exanthematous febrile infections which are dengue- or rubella-like in infected individuals. Despite having been discovered in Uganda for almost 60 years, (Source: Journal of Infection)



Zika fever and congenital Zika syndrome: An unexpected emerging arboviral disease

Mon, 29 Feb 2016 00:00:00 +0100

Unlike its mosquito-borne relatives, such as dengue, West Nile, and Japanese encephalitis viruses, which can cause severe human diseases, Zika virus (ZIKV) has emerged from obscurity by its association with a suspected “congenital Zika syndrome”, while causing asymptomatic or mild exanthematous febrile infections which are dengue- or rubella-like in infected individuals. Despite having been discovered in Uganda for almost 60 years, (Source: Journal of Infection)



Post-vaccination MDEM associated with MOG antibody in a subclinical infected boy

Wed, 24 Feb 2016 00:00:00 +0100

In this report, we describe the case of a 6-year-old Japanese boy who had multiphasic disseminated encephalomyelitis (MDEM), and was positive for both anti-myelin oligodendrocyte glycoprotein (MOG) antibodies and Chlamydophila pneumoniae antibodies. After vaccinations that were the second one for measles and rubella, and the booster immunization for Japanese encephalitis, the patient presented with fever, headache, vomiting, and a change in personality. (Source: Brain and Development)

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Post-vaccination MDEM associated with MOG antibody in a subclinical Chlamydia infected boy

Wed, 24 Feb 2016 00:00:00 +0100

In this report, we describe the case of a 6-year-old Japanese boy who had multiphasic disseminated encephalomyelitis (MDEM), and was positive for both anti-myelin oligodendrocyte glycoprotein (MOG) antibodies and Chlamydophila pneumoniae antibodies. After vaccinations that were the second one for measles and rubella, and the booster immunization for Japanese encephalitis, the patient presented with fever, headache, vomiting, and a change in personality. (Source: Brain and Development)



The Latest On Zika: Infection In Utero May Trigger Mental Illness

Mon, 22 Feb 2016 23:16:01 +0100

The Zika virus, which is spread by the Aedes aegypti mosquito, is strongly suspected to be linked to a new wave of microcephaly cases in Brazil. Babies born with the birth defect have smaller heads and sometimes brains that aren't fully developed, which can result in life-long developmental problems.    Zika is currently spreading through Central and South America and the Caribbean, and with the high volume of news about the virus, it's tough to stay up-to-date. Check out our full coverage, or read our daily recaps. Here are seven updates, opinions and developments to know about now:   1. Confirmation of Zika's connection to microcephaly is expected in May   The U.S. Centers for Disease Control and Prevention is launching the largest government-led s...



Zika News: Fetal Exposure & Mental Health Risk, WHO Guidelines, Symptom Stat Questioned (FREE)

Mon, 22 Feb 2016 00:00:00 +0100

By Amy Orciari Herman Edited by André Sofair, MD, MPH Here's the latest Zika news:Researchers are concerned that Zika infection in utero might predispose children to mental health conditions such as ADHD, autism, and schizophrenia, the New York Times reports. The virus "closely resembles" other infectious organisms (e.g., rubella) that … (Source: Physician's First Watch current issue)



Current views and advances on Paediatric Virology: An update for paediatric trainees.

Sat, 20 Feb 2016 10:15:03 +0100

Authors: Mammas IN, Greenough A, Theodoridou M, Kramvis A, Christaki I, Koutsaftiki C, Koutsaki M, Portaliou DM, Kostagianni G, Panagopoulou P, Sourvinos G, Spandidos DA Abstract Paediatric Virology is a bold new scientific field, which combines Paediatrics with Virology, Epidemiology, Molecular Medicine, Evidence-based Medicine, Clinical Governance, Quality Improvement, Pharmacology and Immunology. The Workshop on Paediatric Virology, which took place on Saturday October 10, 2015 in Athens, Greece, provided an overview of recent views and advances on viral infections occurring in neonates and children. It was included in the official programme of the 20th World Congress on Advances in Oncology and the 18th International Symposium on Molecular Medicine, which attracted over 500 del...



Use of rapid needs assessment as a tool to identify vaccination delays in Guatemala and Peru.

Fri, 19 Feb 2016 00:00:00 +0100

CONCLUSIONS: RNA is a fast and effective method to identify timely vaccine coverage and derive a hypothesis of factors possibly associated with vaccination delay. PMID: 26902545 [PubMed - as supplied by publisher] (Source: Vaccine)

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Isolation of vaccine-derived measles and rubella viruses, not as pathogens but by chance, from children with acute respiratory infections.

Fri, 19 Feb 2016 00:00:00 +0100

Authors: Aoki Y, Matoba Y, Tanaka S, Yahagi K, Ito S, Yoshida H, Itagaki T, Mizuta K PMID: 26902222 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)



World Health Organization responds to growing health needs in Yemen, calls for increased access

Thu, 18 Feb 2016 09:16:04 +0100

17 February 2016 Despite facing significant challenges as a result of the ongoing conflict in Yemen, WHO continues to respond to the increasing health needs of millions of people across the country. Since the beginning of the crisis, WHO has reached more than seven million people in 23 governorates through the provision of medicines, medical supplies, mobile medical teams and mobile clinics. More than five million children below the age of five have been vaccinated against polio, measles and rubella by WHO and partners. WHO has also provided more than 19 million litres of safe water and one million litres of fuel to health facilities and camps hosting internally displaced persons. In Taiz governorate, where hundreds of thousands of people are virtually cut off from humanitarian aid, WHO h...



Fuchs' Uveitis Syndrome: No Longer a Syndrome?

Wed, 17 Feb 2016 14:25:02 +0100

CONCLUSIONS: RV is the leading cause of FUS. Cytokine-based findings mirror a viral etiology and chronic low-grade inflammation. RV-associated FUS represents a common pathway of intraocular RV inoculation after congenital or acquired infection. Other causes, including HSV and CMV, may lead to FUS. PMID: 26222767 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)



Anti-infectious human vaccination in historical perspective.

Wed, 17 Feb 2016 14:23:02 +0100

Authors: D'Amelio E, Salemi S, D'Amelio R Abstract A brief history of vaccination is presented since the Jenner's observation, through the first golden age of vaccinology (from Pasteur's era to 1938), the second golden age (from 1940 to 1970), until the current period. In the first golden age, live, such as Bacille Calmette Guérin (BCG), and yellow fever, inactivated, such as typhoid, cholera, plague, and influenza, and subunit vaccines, such as tetanus and diphtheria toxoids, have been developed. In the second golden age, the cell culture technology enabled polio, measles, mumps, and rubella vaccines be developed. In the era of modern vaccines, in addition to the conjugate polysaccharide, hepatitis A, oral typhoid, and varicella vaccines, the advent of molecular biology enabled t...



Novel COL4A1 mutation in an infant with severe dysmorphic syndrome with schizencephaly, periventricular calcifications, and cataract resembling congenital infection

Tue, 16 Feb 2016 00:00:00 +0100

ConclusionWe suggest that COL4A1 testing should be considered in patients with schizencephaly as well as with phenotype suggesting TORCH infection without any proven etiological factors. Birth Defects Research (Part A), 2016. © 2016 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)

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What Sunglasses in New York and Vaccines Have in Common

Mon, 15 Feb 2016 22:16:08 +0100

Vaccines and autism are in the news... again. This time, Melinda Gates' recent remarks at Davos got me thinking about a strange vaccines analogy. Often, the lack of widespread vaccinations leads to unsettling news headlines. As an example from 2014, a record high number of measles cases (667) was uncovered since the disease was considered eliminated in 2000. This did not transpire in one of the African countries that the Gates Foundation targets for funding vaccine campaigns, but in one of the most developed countries in the world and in the history of time. Before I demystify my analogy, let me ask a question: How can a celebrity hide in plain sight in a place you normally don't find them? Let's say in downtown Berkeley, California where I went to college, a colorful place where tight-jea...



Analysis of the temperature sensitivity of Japanese rubella vaccine strain TO-336.vac and its effect on immunogenicity in the guinea pig.

Fri, 12 Feb 2016 00:00:00 +0100

In this study, we generated infectious clones of TO-336.vac, a Japanese domestic vaccine, TO-336.GMK5, the parental virus of TO-336.vac, and their mutants, and determined the molecular bases of their temperature sensitivity and immunogenicity in guinea pigs. The results revealed that Ser(1159) in the non-structural protein-coding region was responsible for the temperature sensitivity of TO-336.vac dominantly, while the structural protein-coding region affected the temperature sensitivity subordinately. The findings further suggested that the temperature sensitivity of TO-336.vac affected the antibody induction in guinea pigs after subcutaneous inoculation. PMID: 26878651 [PubMed - as supplied by publisher] (Source: Virology)



The Many Harms of Politicizing Fetal Tissue Research to Attack Abortion Rights

Wed, 10 Feb 2016 20:28:35 +0100

Fetal tissue research has led to major advances in human health, including the virtual elimination of diseases such as polio, measles and rubella in the United States. However, according to a new analysis in the Guttmacher Policy Review, this critical avenue of medical research now finds itself at the center of a political firestorm instigated by antiabortion activists and lawmakers, who are using it to attack abortion rights generally and the leading reproductive health provider Planned Parenthood in particular. (Source: The Guttmacher Institute)



A receptor heteromer mediates the male perception of female attractants in plants

Wed, 10 Feb 2016 00:00:00 +0100

Nature advance online publication 10 February 2016. doi:10.1038/nature16975 Authors: Tong Wang, Liang Liang, Yong Xue, Peng-Fei Jia, Wei Chen, Meng-Xia Zhang, Ying-Chun Wang, Hong-Ju Li & Wei-Cai Yang Sexual reproduction requires recognition between the male and female gametes. In flowering plants, the immobile sperms are delivered to the ovule-enclosed female gametophyte by guided pollen tube growth. Although the female gametophyte-secreted peptides have been identified to be the chemotactic attractant to the pollen tube, the male receptor(s) is still unknown. Here we identify a cell-surface receptor heteromer, MDIS1–MIK, on the pollen tube that perceives female attractant LURE1 in Arabidopsis thaliana. MDIS1, MIK1 and MIK2 are plasma-membrane-localized receptor-like kinases with e...



Nigeria: Nigeria Cracked Polio. So Why Does It Have 3.5 Million Unvaccinated Babies?

Tue, 09 Feb 2016 14:43:56 +0100

[The Conversation Africa] Over 20 million children across the globe have not been vaccinated against measles, tetanus, rubella or polio. Half of them come from ten countries, five of which are in Africa. (Source: AllAfrica News: Polio)



Matter: Scientists Seek Answers on Zika in Other Viruses

Mon, 08 Feb 2016 10:52:02 +0100

Researchers found clues about how infections like rubella injure fetuses. That can aid research into the potential link between Zika and microcephaly. (Source: NYT Health)



Scientists Investigate How Viruses Like Zika Cause Birth Defects

Mon, 08 Feb 2016 10:52:02 +0100

Understanding how infections like rubella injure fetuses may aid research into the potential link between Zika and microcephaly. (Source: NYT Health)



Slow Progress In Finalizing Measles And Rubella Elimination In The European Region [Eliminating Measles & Rubella]

Mon, 08 Feb 2016 00:00:00 +0100

All countries in the World Health Organization European Region committed to eliminating endemic transmission of measles and rubella by 2015, and disease incidence has decreased dramatically. However, there was little progress between 2012 and 2013, and the goal will likely not be achieved on time. Genuine political commitment, increased technical capacity, and greater public awareness are urgently needed, especially in Western Europe. (Source: Health Affairs)



Combining Global Elimination Of Measles And Rubella With Strengthening Of Health Systems In Developing Countries [Eliminating Measles & Rubella]

Mon, 08 Feb 2016 00:00:00 +0100

We describe lessons learned from the successful elimination of measles and rubella in the Americas and elsewhere that strive to strengthen national health systems to both improve vaccine uptake and confront emerging threats. The elimination of measles and rubella provides opportunities for nations to strengthen health systems and thus to both reduce inequities and ensure national health security. (Source: Health Affairs)

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Since The Start Of The Vaccines For Children Program, Uptake Has Increased, And Most Disparities Have Decreased [Children's Vaccination In The United States]

Mon, 08 Feb 2016 00:00:00 +0100

This study examined the impact that this intervention had on race and ethnicity–related and income-related disparities for diphtheria-tetanus-acellular pertussis, measles-mumps-rubella, and polio vaccinations, using data from the National Immunization Survey, 1995–2013. Vaccination rates increased across all races, ethnicities, and income groups following the introduction of the Vaccines for Children program. Disparities among race and ethnic groups narrowed considerably over time since the introduction of the vaccine program, although income-related disparities changed at different rates within racial and ethnic groups and in some cases increased. Government interventions aimed solely at reducing certain financial barriers to vaccination may fail to address other important asp...



Factors Associated with Parental Refusal of Routine Vaccination in the Czech Republic.

Thu, 04 Feb 2016 17:52:02 +0100

CONCLUSION: We observed increasing trend of routine vaccination refusal in children during the last ten years (compared to situation in the year 2004, p<0.001). The most important factors associated with this progression were distrust to vaccination, fear of some vaccine components and fear of adverse reactions. PMID: 26841145 [PubMed - as supplied by publisher] (Source: Central European Journal of Public Health)



Congenital rubella syndrome with death from interstitial pneumonia

Wed, 03 Feb 2016 00:00:00 +0100

We report the case of a patient with CRS who died of respiratory failure caused by interstitial pneumonia. Thrombocytopenia had been present for approximately 1 month after birth, and the patient presented with sudden lung hemorrhage at 64 days old. Thereafter, respiratory condition deteriorated, and the patient died at 107 days old. Given that infants with CRS who have thrombocytopenia and interstitial pneumonia have a high risk of death, they should be monitored carefully for potential complications. (Source: Pediatrics International)



The Latest On Zika: New Countries Are Added To The CDC's Watch List

Tue, 02 Feb 2016 20:15:29 +0100

On Monday the U.S. Centers for Disease Control and Prevention added four countries and territories to its growing list of places with active Zika virus transmissions, which means that the cases occurred locally, rather than in travelers returning from a place where they acquired the virus. So far, no local cases of Zika have been reported in the United States.  The virus, which is spread by the Aedes aegypti mosquito, is strongly suspected to be linked to a new wave of microcephaly cases in Brazil. Babies born with the birth defect have smaller heads and brains that aren't fully developed, which can result in life-long developmental problems.    With the high volume of news about the Zika virus, it's tough to stay up-to-date. Check out our full coverage, or re...



Zika Virus Prompts Activists To Push For Legal Abortions In Brazil

Tue, 02 Feb 2016 17:21:33 +0100

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Brazil Wages War against Zika Virus on Several Fronts

Tue, 02 Feb 2016 14:08:52 +0100

In the country’s capital, Brazilian President Dilma Rousseff oversees one of the military operations against the Aedes Aegypti mosquito carried out at a national level in the last few days to curb the spread of the Zika virus. Credit: Roberto Stuckert Filho/PRBy Mario OsavaRIO DE JANEIRO, Feb 2 2016 (IPS)Brazil is deploying 220,000 troops to wage war against the Zika virus, in response to the alarm caused by the birth of thousands of children with abnormally small heads. But eradicating the Aedes aegypti mosquito requires battles on many fronts, including science and the pharmaceutical industry.The Zika virus, transmitted by the Aedes aegypti mosquito, like dengue and Chikungunya fever, is blamed for the current epidemic of microcephaly, which has frightened people in Brazil and could hu...



Ophthalmological findings in infants with microcephaly and presumable intra-uterus Zika virus infection

Tue, 02 Feb 2016 13:36:02 +0100

Conclusions: Patients presented normal anterior segment and important macular and optic nerve abnormalities. Further studies will assess the visual significance of these alterations.RESUMO Introdução: No ano de 2015, foi identificado no Brasil um aumento da prevalência de microcefalia em vinte vezes. Esta malformação foi associada pelo Ministério da Saúde à transmissão vertical do Zika vírus (ZIKV). Método: Investigamos dez lactentes com diagnóstico clínico presumido de microcefalia relacionada à ZIKV, que apresentavam anormalidades oculares, nascidos entre maio e dezembro de 2015. Resultados: Sete mães (70,0%) relataram sintomas (mal-estar, rash e artralgia) durante a gestação, sendo seis (85,7%) no primeiro trimestre. No dia da avaliação nenhuma alteração ocular foi ...



From Rubella to Zika: pregnancy, disability, abortion | Salim Al-Gailani

Fri, 29 Jan 2016 08:26:10 +0100

Current concerns about Zika and microcephaly recall similar anxieties about maternal infection with Rubella in the 1940s, ’50s and ’60s. Salim Al-Gailani explains what we can learn by comparing the two diseases. It’s early spring in London. Some of Britain’s leading medical researchers have convened to discuss alarming new evidence linking a virus long presumed to be harmless with a spate of defects in newborn babies. It’s not 2016, it’s 1946, and the disease is not Zika, but German Measles, or Rubella. For most patients Rubella produces only a minor rash and fever. But when contracted by women during early pregnancy, the virus may result in miscarriage, infant death, or a range of often life-shaping disabilities, such as deafblindness. Increased awareness of the risk of matern...



Local Strep B guidelines must be reviewed regularly, audit says

Fri, 29 Jan 2016 00:00:00 +0100

Royal College of Obstetricians and Gynaecologists’ audit finds care in many trusts is out of step with national guidelinesRelated items from OnMedicaPregnant women will no longer to be screened for rubella susceptibilityScreen pregnant women for group Strep BDoctors and midwives welcome clear alcohol adviceVBAC clinically safe choice for most women (Source: OnMedica Latest News)



Insights into epidemiology of human parvovirus B19 and detection of an unusual genotype 2 variant, Bulgaria, 2004 to 2013

Thu, 28 Jan 2016 00:00:00 +0100

The present study aimed to determine the role of human parvovirus ?19 (B19V) as an aetiological agent in measles and rubella negative fever/rash patients from Bulgaria between 2004 and 2013. A total of 1,266 sera from all over the country were tested for B19V IgM antibodies and all positives were further investigated by polymerase chain reaction (PCR). Overall, 280 sera (22%) were B19V IgM positive and 227 of these (81%) were also PCR positive. The highest number of IgM positives was found among five to nine year-old children (27%). Eight infected women gave birth to healthy children; one fetus was aborted with hydrops fetalis. Of the 55 genetic sequences obtained, 54 belonged to genotype 1a and one grouped as a genotype 2 outlier. Phylogenetic analysis of all available genotype 2 sequence...

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The effect of sucrose as pain relief/comfort during immunisation of 15‐month‐old children in health care centres: a randomised controlled trial

Thu, 28 Jan 2016 00:00:00 +0100

ConclusionThis trial revealed that 30% sucrose orally has a calming and pain‐relieving effect on 15‐month‐old infants during immunisation. Relevance to clinical practicePublic health nurses should use a 30% sucrose solution for pain relief during immunisation of 15‐month‐old infants. (Source: Journal of Clinical Nursing)



Pregnant women will no longer to be screened for rubella susceptibility

Thu, 28 Jan 2016 00:00:00 +0100

Screening of pregnant women in England on 1 April, Public Health England saysRelated items from OnMedicaGlobal measles deaths reach historic lowMeasles rates show steady declinePregnant women to be offered pertussis vaccine (Source: OnMedica Latest News)



Insights into epidemiology of human parvovirus B19 and detection of an unusual genotype 2 variant, Bulgaria, 2004 to 2013.

Thu, 28 Jan 2016 00:00:00 +0100

Authors: Ivanova SK, Mihneva ZG, Toshev AK, Kovaleva VP, Andonova LG, Muller CP, Hübschen JM Abstract The present study aimed to determine the role of human parvovirus В19 (B19V) as an aetiological agent in measles and rubella negative fever/rash patients from Bulgaria between 2004 and 2013. A total of 1,266 sera from all over the country were tested for B19V IgM antibodies and all positives were further investigated by polymerase chain reaction (PCR). Overall, 280 sera (22%) were B19V IgM positive and 227 of these (81%) were also PCR positive. The highest number of IgM positives was found among five to nine year-old children (27%). Eight infected women gave birth to healthy children; one fetus was aborted with hydrops fetalis. Of the 55 genetic sequences obtained, 54 belonged to...



Pregnant women will no longer be screened for rubella after cases are 'virtually eliminated' by MMR vaccine 

Wed, 27 Jan 2016 23:40:24 +0100

Public Health England said infection rates for the virus, also known as German measles, are so low in the UK that rubella in pregnancy is now 'very rare' and screening will end in April. (Source: the Mail online | Health)



Rubella screenings cut for pregnant women

Wed, 27 Jan 2016 16:21:39 +0100

From 1 April 2016, pregnant women in England will no longer be given rubella (German measles) susceptibility screening, Public Health England (PHE) confirmed.c Health England (PHE) confirmed Hide related content:  Show related content read more (Source: Nursing in Practice)

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Rubella screening to end next April

Wed, 27 Jan 2016 15:13:04 +0100

From 1 April 2016, pregnant women in England will no longer be given rubella (German measles) susceptibility screening, Public Health England (PHE) confirmed. Hide related content:  Show related content read more (Source: Management in Practice)



Rubella screening in pregnancy to end as disease 'eliminated' in Britain

Wed, 27 Jan 2016 14:23:35 +0100

Pregnant women will no longer be screened for rubella susceptibility after Public Health England said the disease was now considered to be eliminated in Britain (Source: Telegraph Health)



Rubella screening to end in England

Wed, 27 Jan 2016 13:50:46 +0100

Pregnant women will no longer have rubella screening in England, officials announce. (Source: BBC News | Health | UK Edition)



Assessing herd immunity against rubella in Japan: a retrospective seroepidemiological analysis of age-dependent transmission dynamics

Wed, 27 Jan 2016 00:00:00 +0100

Conclusions An elevated age at rubella virus infection and the presence of susceptible pockets among adults were observed in Japan. Although, overall, the absolute number of rubella cases has steadily declined in Japan, the elevated age of rubella cases, along with increased numbers of susceptible adults, contributed to the observation of as many as 45 congenital rubella syndrome (CRS) cases, which calls for supplementary vaccination among susceptible adults. Assessing herd immunity is considered essential for routinely monitoring the risk of future rubella epidemics and CRS cases. (Source: BMJ Open)



Rubella screening in pregnancy to end

Wed, 27 Jan 2016 00:00:00 +0100

Public Health England has announced that rubella (German measles) susceptibility screening in pregnancy will end in England on 1 April 2016. (Source: NHS Networks)

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Well begun is half done: rubella virus perturbs autophagy signalling, thereby facilitating the construction of viral replication compartments

Wed, 27 Jan 2016 00:00:00 +0100

The rubella virus is the causative agent of postnatal German measles and the congenital rubella syndrome. The majority of the rubella virus replication complexes originate from the endomembrane system. The rubella virus perturbs the signalling pathways regulating the formation of autophagic membranes in the infected cells, including the Ras/Raf/MEK/ERK and PI3K/Akt pathways. It is widely accepted that these pathways inhibit autophagy. In contrast, the class III PI3K enzymes are essential for autophagy initiation. (Source: Medical Hypotheses)



Well begun is half done: Rubella virus perturbs autophagy signaling, thereby facilitating the construction of viral replication compartments

Wed, 27 Jan 2016 00:00:00 +0100

The rubella virus is the causative agent of postnatal German measles and the congenital rubella syndrome. The majority of the rubella virus replication complexes originate from the endomembrane system. The rubella virus perturbs the signaling pathways regulating the formation of autophagic membranes in the infected cells, including the Ras/Raf/MEK/ERK and PI3K/Akt pathways. It is widely accepted that these pathways inhibit autophagy. In contrast, the class III PI3K enzymes are essential for autophagy initiation. (Source: Medical Hypotheses)



Researchers study motivations of parents who refuse to vaccinate children

Sun, 24 Jan 2016 03:26:57 +0100

Pilot study investigates why parents choose not to vaccinate and why many do not to disclose that their children aren’t immunised, potentially putting others at riskThe health of pregnant women and their babies is at risk from parents who refuse to disclose that their children have not been vaccinated, according to researchers in Western Australia who have launched a pilot study to investigate the motivations of anti-vaccinators.Dr Bronwyn Harman, a families researcher with Edith Cowan University’s school of psychology and social science in Western Australia, said unvaccinated children could be carrying diseases such as rubella and whooping cough that are dangerous to pregnant women and newborns. Continue reading... (Source: Guardian Unlimited Science)



Why Facebook founder Mark Zuckerberg was RIGHT to vaccinate daughter

Thu, 21 Jan 2016 19:27:54 +0100

Failing to vaccinate children leaves them at risk of catching life-threatening diseases such as meningitis, tetanus and rubella, says Dr Anita Milicic of the University of Oxford. (Source: the Mail online | Health)



Gambia: Keep It Up!

Tue, 19 Jan 2016 14:06:36 +0100

[The Point] The Ministry of Health and Social Welfare has re-committed itself to embarking on a measles-Rubella prevention campaign next month. (Source: AllAfrica News: Health and Medicine)

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Evaluation of measles-rubella vaccination for mothers in early puerperal phase.

Tue, 19 Jan 2016 00:00:00 +0100

CONCLUSION: MR vaccination in the early puerperal phase is considered an effective way to prevent the diseases, regardless of the mother's immunological status and hormonal milieu. PMID: 26801065 [PubMed - as supplied by publisher] (Source: Vaccine)



Chemical Constituents of Adina rubella

Sat, 16 Jan 2016 00:00:00 +0100

(Source: Chemistry of Natural Compounds)



Migration & Measles Prevention

Thu, 14 Jan 2016 15:57:52 +0100

Story by Carmela Burke, American Red Cross Volunteer, Los Angeles, California Migrants’ stories and photos appear above the newspaper fold line.  Images dominate traditional and social media which draw attention to their harrowing journeys through Asia, the Middle East, and Europe. Rand Corporation analyst Shelly Culbertson cites a staggering statistic from the United Nations Refugee Agency, (UNHCR): “60 million people have been displaced due to war, conflict and persecution—the highest level of displacement in the history of the world.” In light of current events, the terms “migrant” and “refugee” are used interchangeably referring to people who flee war, conflict and/or persecution. The American Red Cross continues to work with the global Red Cross and Red Crescent netwo...



The key role of rubella virus glycoproteins in the formation of immune response, and perspectives on their use in the development of new recombinant vaccines.

Thu, 14 Jan 2016 00:00:00 +0100

Authors: Petrova EK, Dmitrieva AA, Trifonova EA, Nikitin NA, Karpova OV Abstract Rubella is a highly contagious viral disease which is mostly threatens to women of reproductive age. Existent live attenuated vaccines are effective enough, but have some drawbacks and are unusable for a certain group of people, including pregnant women and people with AIDS and other immunodeficiency. Thereby the development of alternative non-replicating, recombinant vaccines undoubtedly is needed. This review discusses the protein E1 and E2 role in formation of immune response and perspectives in development of new generation recombinant vaccines using them. PMID: 26776468 [PubMed - as supplied by publisher] (Source: Vaccine)



Vaccinations and childhood type 1 diabetes mellitus: a meta-analysis of observational studies

Wed, 13 Jan 2016 22:45:25 +0100

Conclusions/interpretation This study provides no evidence of an association between routine vaccinations and childhood type 1 diabetes. (Source: Diabetologia)

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Unusual clinical manifestations of rubella in the elderly

Mon, 11 Jan 2016 00:00:00 +0100

(Source: International Journal of Dermatology)



Vaccination and Induction of Autoimmune Diseases.

Mon, 04 Jan 2016 00:00:00 +0100

Authors: Toussirot É, Bereau M Abstract Vaccines have been suspected of playing a role in inducing autoimmune disease (AID) for a long time. However, apart from certain specific vaccine strains and complications (such as the swine flu vaccine and Guillain- Barré syndrome in 1976, thrombocytopenia and the Measles-Mumps-Rubella vaccine), this role has not been established. In spite of this, many isolated cases or series of cases of arthritis, vasculitis, and central or peripheral nervous system symptoms following vaccination have been reported. These cases tend to be very infrequent and usually only the short-term outcomes are described. This paper will examine the arguments for and against the relationship between vaccines and AID, bearing in mind that no association between the t...



Neuroimaging in Aicardi-Goutieres syndrome: Biomarkers for a progressive encephalopathy

Mon, 28 Dec 2015 00:00:00 +0100

In 1984, 2 pediatric neurologists, Jean Aicardi and Françoise Goutières, published their seminal case report of 8 patients (from 5 families) with a devastating neonatal encephalopathy characterized by striking cerebral calcifications, white matter hypodensities, visualized on CT, accompanied by a persistent CSF lymphocytosis.1 Notably, the neuroradiologic findings suggested a perinatal toxoplasmosis, other (syphilis, varicella-zoster, parvovirus b19), rubella, cytomegalovirus, and herpes (TORCH) infection, and these patients often have an elevation of interferon-α in the CSF.2,3 Three decades of highly productive clinical and scientific investigation of Aicardi-Goutières syndrome (AGS) has led to the discovery of 7 causative genes and the realization that mutatio...



Applications of geographic information systems in public health: A geospatial approach to analyzing MMR immunization uptake in Alberta.

Mon, 21 Dec 2015 22:04:02 +0100

CONCLUSION: This research provides a localized geographic approach to assessing MMR immunization rates in Alberta. Findings from this research can be used to target public health interventions to specific areas that exhibit the lowest immunization rates. These results can also be used for hypothesis generation in future research on barriers to immunization uptake. PMID: 26680425 [PubMed - in process] (Source: Canadian Journal of Public Health)



Epidemiological characteristics of rubella and congenital rubella syndrome in the 2012-2013 epidemics in Tokyo, Japan.

Fri, 18 Dec 2015 08:28:03 +0100

Authors: Sugishita Y, Shimatani N, Katow S, Takahashi T, Hori N Abstract A large rubella outbreak has been observed since June 2012 in Tokyo, Japan, and a rapid increase in the number of congenital rubella syndrome (CRS) cases have also been reported in Japan since October 2012. All the clinically diagnosed and laboratory-confirmed rubella cases reported in Tokyo from January 2012 to December 2013 and all the laboratory-confirmed CRS cases from January 2012 to March 2014 were analyzed. In total, 4,116 rubella cases were reported in Tokyo. Of these, 77.2% (n=3,176) were male; the highest number of cases occurred in males aged 35-39 years and in females aged 20-24 years. Complications included arthralgia/arthritis (19.4%), thrombocytopenic purpura (0.5%), hepatic dysfunction (0.3%), ...

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Serological statuses of pregnant women in an urban Brazilian population before and after the 2008 rubella immunization campaign.

Fri, 18 Dec 2015 00:00:00 +0100

CONCLUSIONS: The decline in the prevalence of pregnant women who were seronegative for rubella to <5% indicates that the 2008 Brazilian rubella immunization campaign was successful in Maceió. PMID: 26707222 [PubMed - as supplied by publisher] (Source: Vaccine)



High sensitivity, high surface area Enzyme-linked Immunosorbent Assay (ELISA).

Thu, 17 Dec 2015 00:00:00 +0100

CONCLUSIONS: The increased surface area of the 3DStack developed using nanoimprinting and press stamping technologies, and the flow pattern between sheets generated by rotating the 3DStack were potential contributors to a more sensitive ELISA-based diagnostic device. PMID: 26684884 [PubMed - in process] (Source: Bio-Medical Materials and Engineering)



The intrathecal, polyspecific antiviral immune response in neurosarcoidosis, acute disseminated encephalomyelitis and autoimmune encephalitis compared to multiple sclerosis in a tertiary hospital cohort

Sun, 13 Dec 2015 00:00:00 +0100

Background: A polyspecific, intrathecal humoral immune response against the neurotropic viruses, measles, rubella and varicella zoster virus, called “MRZ reaction” (MRZR), is present in the majority of patients with multiple sclerosis (MS). Neurosarcoidosis (NS) and acute disseminated encephalomyelitis (ADEM) are important clinical differential diagnoses of MS. Autoimmune encephalitis (AIE) represents a well characterized autoimmune CNS disorder with intrathecal antibody synthesis. The aim of this study was to investigate the specificity of MRZR for MS in patients with NS, ADEM and AIE for the first time, and to compare it with the diagnostic value of oligoclonal bands (OCB).Patients and methodsTwenty-two patients with NS, 17 with AIE, 8 with ADEM and 33 with MS serving as controls wer...



Safety and Immunogenicity of a Quadrivalent Meningococcal Conjugate Vaccine and Commonly Administered Vaccines After Coadministration

Sat, 12 Dec 2015 19:03:42 +0100

Conclusions: With no clinically relevant vaccine interactions or impact on vaccine reactogenicity or safety, these results support the coadministration of MenACWY-CRM with routine vaccines in all age groups. (Source: The Pediatric Infectious Disease Journal)



Vaccine attitude change: What works, what doesn't [Social Sciences]

Tue, 08 Dec 2015 00:00:00 +0100

Betsch et al. (1) argue that our intervention failed to affect “true” vaccine skeptics’ attitudes, and that the findings of our paper (2) actually support the use of an intervention aimed at dispelling myths linking measles, mumps, and rubella (MMR) vaccines and autism. Our paper (2) focuses on analyses of... (Source: Proceedings of the National Academy of Sciences)



Survival Analysis for Predictive Factors of Delay Vaccination in Iranian Children

Fri, 04 Dec 2015 20:30:00 +0100

Conclusions: Delay time duration of vaccination increased by faring from capital to the east south. Moreover, concentration of foreign immigrants in big cities and low level of mother education are the most predictors of delayed vaccination. Educational intervention should focus on immigrants and mothers with low education level.Keywords: Children, delay vaccination, Iran, mumps‑measles‑rubella, risk factors, survival analysis (Source: International Journal of Preventive Medicine)



Rubella antibody status of patients attending a south-west London antenatal clinic, 2007-2012.

Wed, 02 Dec 2015 21:26:18 +0100

In this study, samples were collected in serum separator tubes at the West Middlesex University Hospital (WMUH) ANC and sent to the laboratory. Rubella status was determined using a third-generation rubella IgG enzyme immunoassay. Any negative results were retested and confirmed using an alternative method. The concentrations were expressed as iu/mL (World Health Organization [WHO] standard). Over a five-year period, the number of rubella-susceptible patients increased from 4.1% to 6.8% of the total number of specimens tested. The current population susceptibility levels seem to be influenced by a number of factors: the target population, age at vaccination and the level of coverage, and exposure to wild virus. PMID: 25265756 [PubMed - indexed for MEDLINE] (Source: British Journal of B...



IJERPH, Vol. 12, Pages 15285-15297: Awareness of Cytomegalovirus Infection among Pregnant Women in Geneva, Switzerland: A Cross-sectional Study

Wed, 02 Dec 2015 00:00:00 +0100

Conclusions: Most women were unaware of CMV infection and its potential risks during pregnancy. It is crucial to improve CMV information given to pregnant women to prevent the risks for the fetus/newborn. (Source: International Journal of Environmental Research and Public Health)

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[Vaccinations in dentistry. An update].

Mon, 30 Nov 2015 22:04:02 +0100

Authors: Abstract The purpose of this current paper is to give a simple update and overview about vaccinations for dental health care workers considering the new guidelines published in February 2014 by the Swiss Federal Office of Public Health. It is recommended to have at least a valid protection against hepatitis B, measles, mumps, rubella, influenza, varicella, diphtheria, tetanus, poliomyelitis and pertussis. Dental health care workers are highly exposed and high risk carriers for inoculable diseases, therefore regular refreshment of vaccinations is necessary for public health and their own health. PMID: 26168689 [PubMed - indexed for MEDLINE] (Source: Schweizer Monatsschrift fur Zahnmedizin)



[Preventive vaccinations in dentistry].

Mon, 30 Nov 2015 22:04:02 +0100

Authors: Rostetter C, Lübbers HT, Kruse AL, Metzler P Abstract The purpose of this current paper is to give a simple update and overview about vaccinations for dental health care workers considering the new guidelines published in February 2014 by the Swiss Federal Office of Public Health. It is recommended to have at least a valid protection against hepatitis B, measles, mumps, rubella, influenza, varicella, diphtheria, tetanus, poliomyelitis and pertussis. Dental health care workers are highly exposed and high risk carriers for inoculable diseases, therefore regular refreshment of vaccinations is necessary for public health and their own health. PMID: 25734399 [PubMed - indexed for MEDLINE] (Source: Schweizer Monatsschrift fur Zahnmedizin)



Analysis of the Auckland 2014 measles outbreak indicates that adolescents and young adults could benefit from catch-up vaccination.

Mon, 30 Nov 2015 21:52:01 +0100

CONCLUSION: Results suggest that an adolescent catch-up immunisation programme would prevent further outbreaks of imported measles. PMID: 26411847 [PubMed - in process] (Source: New Zealand Medical Journal)



Viral Skin Diseases.

Mon, 30 Nov 2015 02:50:19 +0100

Authors: Ramdass P, Mullick S, Farber HF Abstract In the vast world of skin diseases, viral skin disorders account for a significant percentage. Most viral skin diseases present with an exanthem (skin rash) and, oftentimes, an accompanying enanthem (lesions involving the mucosal membrane). In this article, the various viral skin diseases are explored, including viral childhood exanthems (measles, rubella, erythema infectiosum, and roseola), herpes viruses (herpes simplex virus, varicella zoster virus, Kaposi sarcoma herpes virus, viral zoonotic infections [orf, monkeypox, ebola, smallpox]), and several other viral skin diseases, such as human papilloma virus, hand, foot, and mouth disease, molluscum contagiosum, and Gianotti-Crosti syndrome. PMID: 26612372 [PubMed - in process...



The role of infection in miscarriage

Mon, 30 Nov 2015 00:00:00 +0100

CONCLUSIONS Further research is required to clarify whether certain infections do increase miscarriage risk and whether screening of newly pregnant women for treatable infections would improve reproductive outcomes. (Source: Human Reproduction Update)

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The 2013 measles outbreak in Sri Lanka: experience from a rural district and implications for measles elimination goals

Mon, 30 Nov 2015 00:00:00 +0100

Conclusion Because the first cases of this outbreak were infants, an increase in susceptible infants due to the change in the vaccine schedule could partly explain the outbreak. (Source: Infectious Diseases of Poverty)



Rubella in a returned traveller.

Mon, 30 Nov 2015 00:00:00 +0100

Authors: Chan T, MacFadden DR, Leis JA PMID: 26622002 [PubMed - as supplied by publisher] (Source: cmaj)



[Measles, mumps, and rubella vaccine. Resurgence of measles in Europe].

Sun, 29 Nov 2015 04:43:35 +0100

Authors: Garcés-Sánchez M, Renales-Toboso M, Bóveda-García M, Díez-Domingo J Abstract Measles is a rash illness of moderate severity and high risk of serious complications, with recovery in several weeks. It is a viral disease caused by one of the most infectious and contagious pathogens that exists, whose only known reservoir is human. In 1998, the European Region of the WHO set a target of eliminating measles by 2010. This goal has not been achieved. Furthermore, it has been observed the resurgence of the disease in some parts of Europe. We review the disease and its vaccines as well as the epidemiological and social factors that have so far prevented the total control of the disease. PMID: 26611100 [PubMed - as supplied by publisher] (Source: Enfermedades Infecciosas y ...