Subscribe: MedWorm: Measles
http://www.medworm.com/rss/medicalfeeds/infectiousdiseases/Measles.xml
Added By: Feedage Forager Feedage Grade B rated
Language: English
Tags:
cases  children  diseases  health  measles  medworm sponsor  outbreak  outbreaks  source  sponsor message  vaccination  vaccine  virus 
Rate this Feed
Rate this feedRate this feedRate this feedRate this feedRate this feed
Rate this feed 1 starRate this feed 2 starRate this feed 3 starRate this feed 4 starRate this feed 5 star

Comments (0)

Feed Details and Statistics Feed Statistics
Preview: MedWorm: Measles

MedWorm: Measles



MedWorm.com provides a medical RSS filtering service. Over 7000 RSS medical sources are combined and output via different filters. This feed contains the latest news and research in the Measles category.



Last Build Date: Tue, 29 Mar 2016 16:31:22 +0100

 



Outbreak of measles in Bhelterghat, Ghanapara and Pekbeki, Goalpara, Assam, India, 2015

Tue, 29 Mar 2016 09:23:38 +0100

Background: Among 21.5 million children globally who did not receive a single dose of measles vaccine in 2013, 6.4 million (30%) were in India, resulting in a large susceptible population at risk for propagating measles outbreaks. On March 20, 2015, a single health facility in Goalpara District in Assam reported 73 children < 18 years with fever and rash. We investigated the suspected measles outbreak to confirm and describe the outbreak, estimate vaccine effectiveness, and propose recommendations for prevention and control measures. (Source: International Journal of Infectious Diseases)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.




Waning maternal measles antibodies in infants

Tue, 29 Mar 2016 09:23:38 +0100

Background: Measles continues to be a major cause globally of childhood morbidity and mortality and was responsible for 145,700 deaths worldwide in 2013. Many countries have now adopted measles elimination targets including China, which was originally slated for elimination in 2012 as part of the WHO's Western Pacific Region measles control plan. This elimination goal was not met despite China's intensive control efforts over several years, and sustained levels of transmission continue to characterize measles epidemiology there. (Source: International Journal of Infectious Diseases)



The impact of increased use of ASHAs on rural immunization coverage in India

Tue, 29 Mar 2016 09:23:38 +0100

Background: Accredited Social Health Activists (ASHAs) are located in rural Indian villages to promote positive health behaviors and facilitate better health care utilization, including vaccination. We calculated the average coverage of the Bacillus Calmette-Guérin vaccine (BCG); Diphtheria, Pertussis, and Tetanus vaccine (DPT); polio vaccine; measles vaccine, and full vaccine coverage (BCG, 3 doses of DPT, 3 doses of polio, and measles vaccine) across districts in India, and evaluated the impact of expanded ASHA presence on changes in district-level vaccine coverage. (Source: International Journal of Infectious Diseases)



Engineering of measles virus to target cancer cells, an attempt

Tue, 29 Mar 2016 09:23:36 +0100

Background: Regardless of general perception as potentially dangerous pathogens, viruses have been exploited and used as vaccine agents or as carriers for gene therapy. Similar positive effects have been observed in case of cancer patients getting infected with viruses, where infection has resulted in temporary tumor regression. Hence, the development of a recombinant virus that selectively infects and kills cancer cells can be a promising anti-cancer tool in near future. Here we made an attempt to generate an oncolytic virus using Measles viral genome (Edmonston strain) backbone and to further arm this recombinant virus with non viral genes of known anti-proliferative activity to enhance its antitumor activity. (Source: International Journal of Infectious Diseases)



An outbreak of measles in Ondo West LGA, Ondo State, Nigeria, February -May, 2013

Tue, 29 Mar 2016 09:23:35 +0100

Background: Measles is a febrile rash illness and highly contagious viral disease associated with high morbidity and mortality. It is the fifth leading cause of death among under-five children worldwide. On 6th May, 2013, suspected measles cases were reported from Ondo West LGA to State Ministry of Health Akure. We investigated the outbreak to confirm diagnosis of measles, assess the magnitude, identify the source of the infection and institute control measures. (Source: International Journal of Infectious Diseases)



Measles among pregnant women in South Kazakhstan in recent times

Tue, 29 Mar 2016 09:23:35 +0100

Background: In recent years, the measles incidence increase has been registered in many regions of Kazakhstan despite the fact that the national program of the infection elimination is in progress. There was its growth by 4,4 times in the Republic and by 2,2 times in the South-Kazakhstan oblast in the year 2014 compared to the year 2013. (Source: International Journal of Infectious Diseases)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.




Time trends in vaccine delivery over two decades in a full-time immunization clinic of a tertiary care centre

Tue, 29 Mar 2016 09:23:35 +0100

In this study we analyze time trends in vaccination provided by this clinic over two decades. (Source: International Journal of Infectious Diseases)



Robert De Niro Pulls Controversial Anti-Vaccination Documentary From Tribeca Film Festival

Sun, 27 Mar 2016 00:38:53 +0100

A controversial anti-vaccination documentary has been pulled from the Tribeca Film Festival lineup after it was met with fierce criticism, festival co-founder Robert De Niro announced on Saturday. De Niro, who had just a day earlier defended showing "Vaxxed: From Cover-Up to Catastrophe," said in a statement "we do not believe it contributes to or furthers the discussion I had hoped for." The actor and the festival were hit with an onslaught of criticism for showing the documentary by the disgraced anti-vax doctor Andrew Wakefield. The documentary claims that the U.S. Centers for Disease Control and Prevention concocted a conspiracy to cover up the "true" reason for America’s rising autism diagnosis rates: vaccines. Extensive research, including studies by the World Health Organ...



Laboratory confirmation of rubella infection in suspected measles cases

Sat, 26 Mar 2016 23:00:00 +0100

This article is protected by copyright. All rights reserved (Source: Journal of Medical Virology)



High-throughput screen identifies potential henipavirus drug target

Sat, 26 Mar 2016 04:00:00 +0100

(PLOS) The henipaviruses are deadly cousins of the more common mumps, measles, and respiratory syncytial viruses. Henipavirus outbreaks are on the rise, but little is known about them. A study published on March 24 in PLOS Pathogens reports the first high-throughput RNA interference screen for host genes that are essential for live henipavirus infection of human cells, and identifies a specific cell protein called fibrillarin as a potential target for drugs against henipaviruses and other paramyxoviruses. (Source: EurekAlert! - Infectious and Emerging Diseases)



Andrew Wakefield, Disgraced Anti-Vax Doctor, Returns With A Documentary At Tribeca Film Fest

Fri, 25 Mar 2016 18:04:09 +0100

Andrew Wakefield is back in the news, thanks to a new, controversial documentary set to premiere at the upcoming Tribeca Film Festival in New York. The film, directed by Wakefield himself, claims that the U.S. Centers for Disease Control and Prevention orchestrated a conspiracy to cover up the "true" reason for America's rising autism diagnosis rates: vaccines.  This is a widely and soundly discredited assertion. Studies from the independent, non-profit Institute of Medicine, the World Health Organization and the CDC have all found that there is no link between receiving vaccines and developing autism spectrum disorder. Instead, what these studies demonstrate is that vaccines are overwhelmingly safe, with very rare cases of side effects, and that they protect children f...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.




Liberia: Measles Outbreak in Margibi

Fri, 25 Mar 2016 14:26:26 +0100

[LINA] Margibi County acting Health Officer has announced an outbreak of measles in the county. (Source: AllAfrica News: Health and Medicine)



Progress Toward Measles EliminationProgress Toward Measles Elimination

Fri, 25 Mar 2016 12:34:28 +0100

Find out what progress has been made to eradicate measles in Nepal. Have the current elimination strategies been effective? Morbidity & Mortality Weekly Report (Source: Medscape Today Headlines)



What are some of the myths – and facts – about vaccination?

Thu, 24 Mar 2016 00:00:00 +0100

What are some of the myths—and facts—about vaccination? (Source: WHO Feature Stories)



Anti-Vaxxers Are Officially To Blame For The Rise In 2 Preventable Diseases

Wed, 23 Mar 2016 19:48:40 +0100

The recent rise in the U.S. of vaccine-preventable diseases has been largely blamed on those who refuse to vaccinate their children. Previous analyses have linked anti-vaxxers to certain outbreaks -- like last year's Disneyland measles outbreak -- but there was still some controversy over the connection.  Now a new review funded by the National Institutes of Health has found a correlation between vaccine refusal and the rise of measles and whooping cough (also known as pertussis), two common vaccine-preventable conditions.  Researchers at Emory University and Johns Hopkins Bloomberg School of Health reviewed reported case data in conjunction with previously published studies to better understand the relationship between vaccine refusal, delay or exemption and the f...



Effect of socioeconomic deprivation on uptake of measles, mumps and rubella vaccination in Liverpool, UK over 16 years: a longitudinal ecological study

Tue, 22 Mar 2016 13:34:21 +0100

Research Articles D. HUNGERFORD, P. MACPHERSON, S. FARMER, S. GHEBREHEWET, D. SEDDON, R. VIVANCOS, A. KEENAN, Epidemiology & Infection, Volume 144 Issue 06, pp 1201-1211Abstract (Source: Epidemiology and Infection)



The inconvenient truth of vaccine refusal

Tue, 22 Mar 2016 13:30:07 +0100

Follow me at @drClaire When I talk to parents who are hesitant about vaccines, what they most want to talk to me about are possible side effects of the vaccine. They worry about everything from fevers and soreness to additives to possible links to autism. They rarely worry about the diseases that vaccines prevent—and that’s what worries me most of all. It is the inconvenient truth of vaccine refusal: when you don’t get vaccinated against an illness, you are more likely to catch it. A study just released in the Journal of the American Medical Association (JAMA) makes this very clear. Researchers looked at information about recent measles and pertussis outbreaks. They found that unvaccinated people made up the majority of those who caught measles and a large proportion of those who cau...



Epidemiology of laboratory confirmed measles virus cases in Amhara Regional State of Ethiopia, 2004–2014

Tue, 22 Mar 2016 00:00:00 +0100

Measles is a highly contagious viral infection causing large outbreaks all over the world. Despite the availability of safe and cost effective vaccine, measles remained endemic with persistent periodic outbrea... (Source: BMC Infectious Diseases)



Improved Measles Vaccination: Contributions of a Travel Clinic

Mon, 21 Mar 2016 23:00:00 +0100

(Source: Clinical Infectious Diseases)



Risk factors for measles infection in 0-7 month old children in China after the 2010 nationwide measles campaign: A multi-site case-control study, 2012-2013.

Sun, 20 Mar 2016 23:00:00 +0100

CONCLUSIONS: Hospital visitation was the largest risk factor for measles infection in infants. Improved hospital infection control practices would accelerate measles elimination in China. PMID: 27013438 [PubMed - as supplied by publisher] (Source: Vaccine)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.




Infectious disease outbreaks pose ongoing threats to health: US, global systems urged to take action

Fri, 18 Mar 2016 16:01:07 +0100

From multistate outbreaks of diseases such as measles among U.S. kids, to the deadly impact of Ebola in West Africa, infectious disease outbreaks pose an ongoing threat to human health. Unfortunately, gaps remain in protecting populations in the U.S. and beyond from those risks, according to experts. (Source: PHPartners.org)



Measles outbreak in a refugee settlement in Calais, France: January to February 2016

Thu, 17 Mar 2016 00:00:00 +0100

We report a measles outbreak in a refugee settlement in Calais, France, between 5 January and 11 February 2016. In total, 13 confirmed measles cases were identified among migrants, healthcare workers in hospital and volunteers working on site. A large scale vaccination campaign was carried out in the settlement within two weeks of outbreak notification. In total, 60% of the estimated target population of 3,500 refugees was vaccinated during the week-long campaign. (Source: Eurosurveillance)



Vaccine Refusal Puts Unvaccinated and Vaccinated at Risk Vaccine Refusal Puts Unvaccinated and Vaccinated at Risk

Wed, 16 Mar 2016 21:46:53 +0100

A recent literature review has revealed that many of the individuals who contracted measles and pertussis in recent outbreaks were either unvaccinated or undervaccinated. Medscape Medical News (Source: Medscape Allergy Headlines)



Unvaccinated kids driving measles, pertussis outbreaks

Wed, 16 Mar 2016 15:53:57 +0100

Steven Reinberg, HealthDay News A look at recent measles outbreaks in the United States finds more than half of the cases involved unvaccinated children. (Source: Health News - UPI.com)



Vaccine Refusal a Driving Force Behind Measles Outbreaks, Study Finds

Wed, 16 Mar 2016 07:00:00 +0100

Title: Vaccine Refusal a Driving Force Behind Measles Outbreaks, Study FindsCategory: Health NewsCreated: 3/15/2016 12:00:00 AMLast Editorial Review: 3/16/2016 12:00:00 AM (Source: MedicineNet Kids Health General)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.




Vaccination aversion has fueled measles and whooping cough outbreaks, study finds

Wed, 16 Mar 2016 01:16:00 +0100

A comprehensive new study of measles and pertussis outbreaks in the United States suggests that adults’ reluctance or refusal to vaccinate themselves and their children has played a key role in the resurgence of diseases that had been largely eradicated in this country. In an analysis published... (Source: Los Angeles Times - Science)



Nonmedical Vaccine Exemptions Account for Large Portion of Recent Measles Cases (FREE)

Wed, 16 Mar 2016 00:00:00 +0100

By Amy Orciari Herman Edited by Lorenzo Di Francesco, MD, FACP, FHM Vaccine refusal accounts for a substantial portion of measles cases since the disease was declared eliminated in the U.S. in 2000, a JAMA … (Source: Physician's First Watch current issue)



Vaccine Refusal a Driving Force Behind Measles Outbreaks, Study Finds

Wed, 16 Mar 2016 00:00:00 +0100

As trend continues, researcher fears more outbreaks of whooping cough, too (Source: Pulmonary Medicine News - Doctors Lounge)



Over Half Of Measles Cases In U.S. Outbreaks Are Unvaccinated -- Often Intentionally

Tue, 15 Mar 2016 23:35:05 +0100

Intentionally unvaccinated individuals are at high risk for catching measles and pertussis and contribute to the measles outbreaks. (Source: Forbes.com Healthcare News)



New Study Shows Just How Dangerous It Is To NOT Vaccinate

Tue, 15 Mar 2016 19:38:09 +0100

Measles -- a disease that was completely eliminated in the United States 15 years ago -- has captured national attention recently, thanks to outbreaks among unvaccinated travelers who have contracted the disease abroad. At the same time, anti-vaccination sentiments have found footing among some parents worried over unfounded safety concerns.  Now, a new study shows just how closely the two phenomena are intertwined. More than half of reported measles cases in recent outbreaks in the U.S. were among unvaccinated individuals -- most of whom were intentionally unvaccinated for philosophical, rather than medical, reasons. In a third of the cases, researchers did not have enough information about the person's vaccination history to tell if they'd been immunized.  A similar patter...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.




Vaccine refusal tied to increased risk of measles and pertussis

Tue, 15 Mar 2016 19:27:52 +0100

Reuters Health - Parents who delay or skip childhood vaccinations even when kids have no medical reason to avoid their shots are contributing to U.S. outbreaks of measles and pertussis, a research review suggests. (Source: Reuters: Health)



No Surprise: Most Measles Victims Are Unvaccinated (CME/CE)

Tue, 15 Mar 2016 19:00:00 +0100

(MedPage Today) -- Pertussis outbreaks, however, have more complex origins (Source: MedPage Today Pediatrics)



Vaccine Refusal Drives Measles Outbreaks: Study

Tue, 15 Mar 2016 18:21:32 +0100

As trend continues, researcher fears more outbreaks of whooping cough, too (Source: WebMD Health)



Vaccine Refusal a Driving Force Behind Measles Outbreaks, Study Finds

Tue, 15 Mar 2016 16:00:00 +0100

As trend continues, researcher fears more outbreaks of whooping cough, too (Source: U.S. News - Health)



'Substantial proportion' of U.S. measles cases linked to anti-vaxxers, study suggests

Tue, 15 Mar 2016 15:01:52 +0100

A recently published study in the Journal of the American Medical Association says “the phenomenon of vaccine refusal” increases the risk for measles among individuals who are not or refuse to get vaccinated, and among those who are already fully vaccinated. (Source: CBC | Health)



Among recent U.S. measles patients, 42% intentionally unvaccinated

Tue, 15 Mar 2016 15:00:00 +0100

In approximately 42% of recent cases of measles in the United States, the patients were intentionally unvaccinated for nonmedical reasons such as religious or philosophical objections to vaccines,... (Source: Pediatric News)



Medical News Today: Refusal to immunize linked to outbreaks of measles and pertussis

Tue, 15 Mar 2016 15:00:00 +0100

As more people seek exemptions for immunization against infectious diseases, figures show that those who do not receive vaccinations are more likely to be involved in an outbreak. (Source: Health News from Medical News Today)



Vaccine Refusal a Driving Force Behind Measles Outbreaks, Study Finds

Tue, 15 Mar 2016 12:00:49 +0100

TUESDAY, March 15, 2016 -- A look at recent measles outbreaks in the United States finds more than half of the cases involved unvaccinated children. Vaccine refusal was also often the culprit in whooping cough (pertussis) outbreaks as well,... (Source: Drugs.com - Daily MedNews)



Efficacy of intralesional immunotherapy for the treatment of warts: A review of the literature

Tue, 15 Mar 2016 00:00:00 +0100

ABSTRACT Warts are common epidermal growths caused by human papillomavirus that often cause significant discomfort and embarrassment. Current treatment options include topical therapies, cryotherapy, laser vaporization, and surgical excision. Many of these options are destructive and may result in scarring, while less aggressive approaches can lead to lesion recurrence. Additionally, these local modalities are not practical for patients with a large number of warts. Systemic approaches such as immunotherapy have demonstrated success in treating multiple lesions by combining a targeted approach with upregulation of the host immune system. An extensive literature review was performed to evaluate the various vaccine antigens that have been used intralesionally to treat cutaneous and anogenita...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.




Causes of Outbreaks of Vaccine-Preventable Diseases in the United States

Tue, 15 Mar 2016 00:00:00 +0100

This evidence review summarizes published reports of measles and pertussis outbreaks to characterize associations with vaccine delay, vaccine refusal, and waning immunity. (Source: JAMA)



MMR vaccination call following recent measles cases

Mon, 14 Mar 2016 00:00:00 +0100

Increase in measles cases since February prompts measles mumps and rubella (MMR) vaccination call. (Source: NHS Networks)



Check your MMR status, public health doctors say

Mon, 14 Mar 2016 00:00:00 +0100

Some 20 cases of measles have been confirmed across England since February Related items from OnMedicaMMR uptake 'highest ever'Measles cases fall quickly after catch-up programmeThird of all measles cases linked to overseas travelMeasles vaccine protects against additional diseases (Source: OnMedica Latest News)



Monitoring the process of measles elimination by serosurveillance data: The Apulian 2012 study.

Mon, 14 Mar 2016 00:00:00 +0100

Authors: Tafuri S, Gallone MS, Gallone MF, Pappagallo MT, Larocca A, Germinario C Abstract In 2003 Italy adopted the National Plan for Measles and Congenital Rubella Elimination, but some outbreaks of measles are still occurring, as the target coverage rate (≥95%) for new-borns has currently not been achieved. In order to support the monitoring of the measles elimination programme, the authors carried out a survey about the seroprevalence of measles among Apulia young adults. The study was carried out from May 2011 to June 2012 among blood donors of the Department of Transfusion Medicine of Policlinico General Hospital in Bari. Subjects were enrolled by a convenience sampling. For each enrolled patient we collected a 5mL serum sample. Collected sera were tested by chemiluminescen...



Measles outbreak feared in South East

Fri, 11 Mar 2016 18:59:48 +0100

Doctors are concerned they are witnessing the start of a measles outbreak in London and the South East. (Source: BBC News | Health | UK Edition)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.




[Correspondence] Changing oral vaccine to inactivated polio vaccine might increase mortality

Fri, 11 Mar 2016 06:34:04 +0100

We, the undersigned, write as physicians and scientists committed to optimising the beneficial effects of vaccines to reduce infant mortality worldwide. In settings with high childhood mortality, live vaccines such as oral polio vaccine (OPV), BCG vaccine, and measles vaccine might have heterologous (non-specific) effects that reduce mortality from diseases other than poliomyelitis, tuberculosis, and measles, respectively, whereas inactivated vaccines might increase all-cause mortality.1 The importance of these effects is controversial. (Source: LANCET)



Waning immunity against mumps in vaccinated young adults, France 2013

Thu, 10 Mar 2016 00:00:00 +0100

In 2013, 15 clusters of mumps were notified in France; 72% (82/114) of the cases had been vaccinated twice with measles-mumps-rubella vaccine. To determine whether the risk of mumps increased with time since the last vaccination, we conducted a case-control study among clusters in universities and military barracks. A confirmed case had an inflammation of a salivary gland plus laboratory confirmation in 2013. A probable case presented with inflammation of a salivary gland in 2013 either lasting for?>?2 days or with epidemiological link to a confirmed case. Controls had no mumps symptoms and attended the same university course, student party or military barracks. We collected clinical and vaccination data via web questionnaire and medical records. We calculated adjusted odds ratios (aOR)...



The impact of Supplementary Immunization Activities on the epidemiology of measles in Tianjin, China

Thu, 10 Mar 2016 00:00:00 +0100

(Source: International Journal of Infectious Diseases)



Waning immunity against mumps in vaccinated young adults, France 2013.

Thu, 10 Mar 2016 00:00:00 +0100

Authors: Vygen S, Fischer A, Meurice L, Mounchetrou Njoya I, Gregoris M, Ndiaye B, Ghenassia A, Poujol I, Stahl JP, Antona D, Le Strat Y, Levy-Bruhl D, Rolland P Abstract In 2013, 15 clusters of mumps were notified in France; 72% (82/114) of the cases had been vaccinated twice with measles-mumps-rubella vaccine. To determine whether the risk of mumps increased with time since the last vaccination, we conducted a case-control study among clusters in universities and military barracks. A confirmed case had an inflammation of a salivary gland plus laboratory confirmation in 2013. A probable case presented with inflammation of a salivary gland in 2013 either lasting for > 2 days or with epidemiological link to a confirmed case. Controls had no mumps symptoms and attended the sam...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.




Genotypes of rubella virus and the epidemiology of rubella infections in the Democratic Republic of the Congo, 2004–2013

Wed, 09 Mar 2016 01:19:05 +0100

ConclusionThis report provides the first information on the genotypes of rubella virus circulating in the DRC. These data contribute to a better understanding of rubella burden and the dynamics of rubella virus circulation in Africa. Efforts to establish rubella surveillance in the DRC are needed to support rubella elimination in Africa. This article is protected by copyright. All rights reserved (Source: Journal of Medical Virology)



Timely immunization completion among children in Vietnam from 2000 to 2011: a multilevel analysis of individual and contextual factors.

Wed, 09 Mar 2016 00:42:01 +0100

CONCLUSION: The EPI should include 'timely immunization completion' as a quality indicator. There should also be greater focus and targeting in rural areas, and among women who have relatively low education, belong to minority groups, and have less household wealth. Further research on this topic using multilevel analysis is needed to better understand how these factors interact. PMID: 26950555 [PubMed - as supplied by publisher] (Source: Global Health Action)



Varicella zoster virus related deaths and hospitalizations in Brazil before the introduction of universal vaccination with the tetraviral vaccine.

Tue, 08 Mar 2016 00:00:00 +0100

CONCLUSIONS: Varicella is associated, in the pre-vaccine period, to significant morbidity and mortality in Brazil. The universal vaccination program is expected to decrease the disease burden from varicella. PMID: 26969400 [PubMed - as supplied by publisher] (Source: Jornal de Pediatria)



Parental Vaccine Hesitancy in Quebec (Canada)

Mon, 07 Mar 2016 16:00:05 +0100

This study aims to contribute to the ongoing reflections on tools and indicators of vaccine hesitancy by providing results of a survey on knowledge, attitudes and beliefs (KAB) of parents in Quebec (Canada). We have compared KAB of parents according to: 1) self-reported vaccination status of their child and 2) hesitation during the vaccination decision. Methods Data were collected through the 2014 Quebec study on vaccination against seasonal influenza and pneumococcal infections, a biennial repeated cross-sectional study in the province of Quebec, Canada. This paper presents the results pertaining to parents’ KAB about vaccination; the full report can be found elsewhere.15 Data were collected through a computer-assisted telephone interview survey conducted between March 18 and April 2...



Nigeria: War Against VPD - After Polio, Measles Should Be Next

Mon, 07 Mar 2016 05:38:23 +0100

[Leadership] When the World Health Organization (WHO) declared Nigeria polio-free, it was celebrated after fighting the battle since 1976. This battle also forced the federal government to set up the National Programme on Immunization (NPI) in the same year. Though the effort failed woefully but in 1979 it was reactivated, leading to the emergence of the Expanded Programme on Immunisation (EPI).The same can be done to other Vaccine Preventable Diseases (VPD), ODIRI UCHENUNU writes. (Source: AllAfrica News: Polio)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.




Exploring models for the roles of health systems' responsiveness and social determinants in explaining universal health coverage and health outcomes.

Sun, 06 Mar 2016 00:54:02 +0100

CONCLUSIONS: This paper adds to the literature on comparative health systems research. National and international health monitoring frameworks need to incorporate indicators on trends in and impacts of other policy sectors on health. This will empower the health sector to carry out public health practices that promote health and health equity. PMID: 26942516 [PubMed - as supplied by publisher] (Source: Global Health Action)



Progress Toward Measles Elimination - Nepal, 2007-2014.

Sat, 05 Mar 2016 15:17:02 +0100

This report updates a previous report (4) and summarizes progress toward measles elimination in Nepal during 2007-2014. During 2007-2014, estimated coverage with the first MCV dose (MCV1) increased from 81% to 88%. Approximately 3.9 and 9.7 million children were vaccinated in SIAs conducted in 2008 and 2014, respectively (1). Reported suspected measles incidence declined by 13% during 2007-2014, from 54 to 47 cases per 1 million population. However, in 2014, 81% of districts did not meet the measles case-based surveillance performance indicator target of ≥2 discarded non-measles cases(¶) per 100,000 population per year. To achieve and maintain measles elimination, additional measures are needed to strengthen routine immunization services to increase coverage with MCV1 and a recently int...



Resurgence of measles in Serbia 2010–2011 highlights the need for supplementary immunization activities

Sat, 05 Mar 2016 13:19:18 +0100

Research Articles J. NEDELJKOVIĆ, S. RAKIĆ ADROVIĆ, G. TASIĆ, V. KOVAČEVIĆ-JOVANOVIĆ, G. LONČAREVIĆ, J. M. HÜBSCHEN, C. P. MULLER, Epidemiology & Infection, Volume 144 Issue 05, pp 1121-1128Abstract (Source: Epidemiology and Infection)



Measles Virus Neutralizing Antibody Response, Cell-Mediated Immunity, and Immunoglobulin G Antibody Avidity Before and After Receipt of a Third Dose of Measles, Mumps, and Rubella Vaccine in Young Adults

Sat, 05 Mar 2016 00:00:00 +0100

Conclusions. Most subjects were seropositive before MMR3 receipt, and very few had a secondary immune response after MMR3 receipt. Similarly, CMI and avidity analyses showed minimal qualitative improvements in immune response after MMR3 receipt. We did not find compelling data to support a routine third dose of MMR vaccine. (Source: The Journal of Infectious Diseases)



Measles and Zika: The Known and Unknown

Fri, 04 Mar 2016 15:42:32 +0100

The mysteries of Zika persist but the tragic similarity between the measles and this virus is that both are devastating to a fetus. (Source: ConsultantLive)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.




Ten-day Measles, 3-day Measles, German Measles, and More

Fri, 04 Mar 2016 13:17:21 +0100

Rubeola, roseola, rubella -- oh my! See what you know about traditional lay terms for these diseases and how they are similar and different. (Source: ConsultantLive)



Progress Toward Measles Elimination — Nepal, 2007–2014

Fri, 04 Mar 2016 12:30:00 +0100

(Source: CDC Morbidity and Mortality Weekly Report)



Spillover effect of HIV-specific foreign aid on immunization services in Nigeria

Fri, 04 Mar 2016 00:00:00 +0100

Conclusions HIV-specific aid had a negative spillover effect on immunization services in Nigeria over the study period. Donors may need to rethink their funding strategies in favour of more horizontal approaches. (Source: International Health)



Progress towards measles elimination in Nepal, 2007–2014.

Fri, 04 Mar 2016 00:00:00 +0100

Authors: PMID: 26946541 [PubMed - in process] (Source: Weekly Epidemiological Record)



Severity of mumps disease is related to MMR vaccination status and viral shedding.

Fri, 04 Mar 2016 00:00:00 +0100

CONCLUSIONS: MMR vaccination was associated with less severe disease among mumps patients. Systemic spread of virus was associated with more severe disease. The elevated salivary viral loads in patients with systemic mumps disease suggest that these patients pose a higher risk for mumps virus transmission. Our study contributes to the understanding of mumps virus pathogenesis and shows the protective effect of MMR vaccination on severity of disease. PMID: 26954106 [PubMed - as supplied by publisher] (Source: Vaccine)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.




Adenovirus Type 7 Pneumonia in Children Who Died from Measles-Associated Pneumonia, Hanoi, Vietnam, 2014.

Thu, 03 Mar 2016 14:05:02 +0100

Authors: Hai le T, Thach HN, Tuan TA, Nam DH, Dien TM, Sato Y, Kumasaka T, Suzuki T, Hanaoka N, Fujimoto T, Katano H, Hasegawa H, Kawachi S, Nakajima N Abstract During a 2014 measles outbreak in Vietnam, postmortem pathologic examination of hospitalized children who died showed that adenovirus type 7 pneumonia was a contributory cause of death in children with measles-associated immune suppression. Adenovirus type 7 pneumonia should be recognized as a major cause of secondary infection after measles. PMID: 26926035 [PubMed - in process] (Source: Emerging Infectious Diseases)



Nigeria: Sokoto Immunises One Million Children Against Measles

Thu, 03 Mar 2016 12:52:01 +0100

[This Day] Sokoto government has immunised one million children against measles and other child killer diseases across the state in the last three months. (Source: AllAfrica News: Health and Medicine)



Stability, biophysical properties and effect of ultracentrifugation and diafiltration on measles virus and mumps virus

Thu, 03 Mar 2016 00:00:00 +0100

Abstract Measles virus and mumps virus (MeV and MuV) are enveloped RNA viruses used for production of live attenuated vaccines for prophylaxis of measles and mumps disease, respectively. For biotechnological production of and basic research on these viruses, the preparation of highly purified and infectious viruses is a prerequisite, and to meet that aim, knowledge of their stability and biophysical properties is crucial. Our goal was to carry out a detailed investigation of the stability of MeV and MuV under various pH, temperature, shear stress, filtration and storage conditions, as well as to evaluate two commonly used purification techniques, ultracentrifugation and diafiltration, with regard to their efficiency and effect on virus properties. Virus titers were estimated by CC...



The measles outbreak in Bulgaria, 2009-2011: An epidemiological assessment and lessons learnt

Thu, 03 Mar 2016 00:00:00 +0100

Measles re-emerged in a nationwide outbreak in Bulgaria from 2009 to 2011 despite reported high vaccination coverage at national level. This followed an eight-year period since the last indigenous cases of measles were detected. The Bulgarian National Centre of Infectious and Parasitic Diseases collated measles surveillance data for 2009-2011. We analysed data for age group, sex, ethnicity, diagnosis confirmation, vaccination, hospitalisation, disease complications, and death and describe the outbreak control measures taken. The outbreak started in April 2009 following an importation of measles virus and affected 24,364 persons, predominantly Roma. Most cases (73%) were among children < 15 years old. Vaccination status was available for 52% (n = 12,630) of cases. Of children 1-14 yea...



Do selective immunisation against tuberculosis and hepatitis B reach the targeted populations? A nationwide register-based study evaluating the recommendations in the Norwegian Childhood Immunisation Programme.

Thu, 03 Mar 2016 00:00:00 +0100

CONCLUSIONS: Children targeted by selective vaccination had lower coverage of the target vaccines than of vaccines in the universal programme, indicating that selective vaccination is challenging. Improved routines for identifying eligible children and delivering the target vaccines are needed. Universal vaccination of all children with these vaccines could be considered. PMID: 26947498 [PubMed - as supplied by publisher] (Source: Vaccine)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.




The measles outbreak in Bulgaria, 2009-2011: An epidemiological assessment and lessons learnt.

Thu, 03 Mar 2016 00:00:00 +0100

Authors: Muscat M, Marinova L, Mankertz A, Gatcheva N, Mihneva Z, Santibanez S, Kunchev A, Filipova R, Kojouharova M Abstract Measles re-emerged in a nationwide outbreak in Bulgaria from 2009 to 2011 despite reported high vaccination coverage at national level. This followed an eight-year period since the last indigenous cases of measles were detected. The Bulgarian National Centre of Infectious and Parasitic Diseases collated measles surveillance data for 2009-2011. We analysed data for age group, sex, ethnicity, diagnosis confirmation, vaccination, hospitalisation, disease complications, and death and describe the outbreak control measures taken. The outbreak started in April 2009 following an importation of measles virus and affected 24,364 persons, predominantly Roma. Most case...



Eradication of measles: remaining challenges

Wed, 02 Mar 2016 00:00:00 +0100

Abstract Measles virus (MeV) is an aerosol-borne and one of the most contagious pathogenic viruses known. Almost every MeV infection becomes clinically manifest and can lead to serious and even fatal complications, especially under conditions of malnutrition in developing countries, where still 115,000 to 160,000 patients die from measles every year. There is no specific antiviral treatment. In addition, MeV infections cause long-lasting memory B and T cell impairment, predisposing people susceptible to opportunistic infections for years. A rare, but fatal long-term consequence of measles is subacute sclerosing panencephalitis. Fifteen years ago (2001), WHO has launched a programme to eliminate measles by a worldwide vaccination strategy. This is promising, because MeV is a hu...



Ministerial conference concludes with pledge to improve access to vaccines

Tue, 01 Mar 2016 08:28:29 +0100

Photo courtesy of Translieu/David Mugithi29 February 2016 – At a landmark Ministerial Conference on Immunization in Africa held from 24 to 25 February, in Addis Ababa, Ethiopia, African Ministers of Health, Finance, Education, Social Affairs and local governments signed a declaration to promote the use of vaccines to protect people of all ages against vaccine-preventable diseases and to close the immunization gap by 2020. One in 5 African children still do not receive all of the most basic vaccines they need against three critical diseases — measles, rubella and neonatal tetanus. Read more  Declaration on universal access to immunization as a cornerstone for health and development in Africa Ministerial Conference on Immunization in Africa, Addis Ababa, 24–25 February 2016 Read mo...



Adenovirus Type 7 Pneumonia in Children Who Died from Measles-Associated Pneumonia, Hanoi, Vietnam, 2014

Tue, 01 Mar 2016 05:00:00 +0100

L. Hai et al. (Source: Emerging Infectious Diseases Journal)



Storytelling in the context of vaccine refusal: a strategy to improve communication and immunisation

Tue, 01 Mar 2016 00:00:00 +0100

The December 2014 outbreak of measles in California impacted over 100 children and served as a reminder that this disease still plagues the USA, even 50 years following the first licensed vaccine. Refusal of vaccination is a complicated and multifaceted issue, one that clearly demands a closer look by paediatricians and public health officials alike. While medical doctors and scientists are trained to practice ‘evidence-based medicine’, and studies of vaccine safety and efficacy speak the language of statistics, there is reason to believe that this is not the most effective strategy for communicating with all groups of parents. Herein, we consider other methods such as narrative practices that employ stories and appeal more directly to parents. We also examine how doctors ...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.




The economic cost of measles: Healthcare, public health and societal costs of the 2012-13 outbreak in Merseyside, UK.

Tue, 01 Mar 2016 00:00:00 +0100

Authors: Ghebrehewet S, Thorrington D, Farmer S, Kearney J, Blissett D, McLeod H, Keenan A Abstract BACKGROUND: Measles is a highly contagious vaccine-preventable infection that caused large outbreaks in England in 2012 and 2013 in areas which failed to achieve herd protection levels (95%) consistently. We sought to quantify the economic costs associated with the 2012-13 Merseyside measles outbreak, relative to the cost of extending preventative vaccination to secure herd protection. METHODS: A costing model based on a critical literature review was developed. A workshop and interviews were held with key stakeholders in the Merseyside outbreak to understand the pathway of a measles case and then quantify healthcare activity and costs for the main NHS providers and public health...



Universal varicella vaccine immunization in Japan.

Tue, 01 Mar 2016 00:00:00 +0100

Authors: Yoshikawa T, Kawamura Y, Ohashi M Abstract In 1974, Japanese scientists developed a live attenuated varicella vaccine based on the Oka strain. The efficacy of the vaccine for the prevention of varicella has been primarily demonstrated in studies conducted in the United States following the adoption of universal immunization using the Oka strain varicella vaccine in 1996. Although the vaccine was developed by Japanese scientists, until recently, the vaccine has been administered on a voluntary basis in Japan resulting in a vaccine coverage rate of approximately 40%. Therefore, Japan initiated universal immunization using the Oka strain varicella vaccine in November 2014. Given the transition from voluntary to universal immunization in Japan, it will also be important to mon...



When Zika Turns Deadlier: How Anti-Vaccination Misinformation Could Exacerbate an International Health Emergency

Mon, 29 Feb 2016 21:47:04 +0100

The world is in a frenzy over the Zika virus. Researchers established a link between its rise in Brazil and cases of congenital microcephaly in babies of infected pregnant women, with infants born with smaller than expected heads and improper brain development. As of November last year, Brazil's northeastern state of Pernambuco recorded 646 babies born with microcephaly. On February 1, the World Health Organization (WHO) declared the virus and its suspected link to birth defects an international public health emergency. Though we don't yet understand the exact relationship between Zika and microcephaly, there is clear cause for concern. But even more troubling is a virus brewing beneath the surface: rumors circulating online that this birth abnormality is actually caused by the Tdap vacci...



Africa: DRC - Children Who Survived Measles Are Now Suffering From Malnutrition and Malaria

Mon, 29 Feb 2016 14:09:47 +0100

[MSF] As the measles epidemic gradually fades in the Tanganyika province of the Democratic Republic of Congo, malaria and malnutrition often form a deadly combination for children. In order to face this situation, MSF - in collaboration with the Congolese Ministry of Health - continues to support the Manono health zone for the management of severe acute malnutrition and pediatric emergencies and is opening a similar project in Kabalo. (Source: AllAfrica News: Health and Medicine)



Nigeria: Sokoto Tackles Polio Vaccine Rejection, One Million Immunized Against Measles

Mon, 29 Feb 2016 13:48:04 +0100

[Daily Trust] Sokoto -One million children have been immunised against measles and other child killer diseases in the last three months in Sokoto State, Commissioner of Health, Dr. Shehu Kakale has said. (Source: AllAfrica News: Polio)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.




Rapid detection of measles virus using reverse transcription loop-mediated isothermal amplification coupled with a disposable lateral flow device

Mon, 29 Feb 2016 00:00:00 +0100

The measles virus (MeV) causes a highly contagious disease and efforts to reduce its spread are critical. A reverse transcription loop-mediated isothermal amplification assay coupled with a disposable lateral flow device (RT-LAMP-LFD) was developed for the rapid detection of MeV. The assay was performed in 40 min at an optimal temperature of 58°C, with endpoint results visualized directly. A probe that was complementary to the RT-LAMP amplicon was designed to enhance assay specificity. Detection limit of the assay was 8.8 copies/μL synthetic RNA, which equals the sensitivity of real-time RT-PCR. (Source: Diagnostic Microbiology and Infectious Disease)



Single motherhood and neonatal and infant mortality in Sierra Leone, Burkina Faso and Burundi

Mon, 29 Feb 2016 00:00:00 +0100

Childhood mortality is a stubborn problem and remains highest in Sub-Saharan Africa (SSA). Existing research on childhood mortality in SSA indicate that most of the childhood deaths are from preventable causes such as diarrhoea, pneumonia, measles, malaria, HIV and underlying malnutrition, acute respiratory infections, whooping cough, tuberculosis, bronchopneumonia, dirty feeding bottles and utensils, inadequate disposal of household refuse and poor storage of drinking water. However, insufficient attention has been given to maternal marital status and childhood mortality relationships. (Source: Public Health)



Mapping the evolutionary trajectories of morbilliviruses: what, where and whither

Sun, 28 Feb 2016 00:00:00 +0100

Publication date: February 2016 Source:Current Opinion in Virology, Volume 16 Author(s): Sham Nambulli, Claire R Sharp, Andrew S Acciardo, J Felix Drexler, W Paul Duprex Morbilliviruses are pathogens of humans and other animals. Live attenuated morbillivirus vaccines have been used to end endemic transmission of measles virus (MV) in many parts of the developed world and to eradicate rinderpest virus. Entry is mediated by two different receptors which govern virus lymphotropism and epitheliotropism. Morbillivirus transmissibility is unparalleled and MV represents the most infectious human pathogen on earth. Their evolutionary origins remain obscure and their potential for adaption to new hosts is poorly understood. It has been suggested that MV could be eradicated. Therefore it is i...



Nigeria: 20 Children Die of Measles in Sokoto State

Fri, 26 Feb 2016 09:20:37 +0100

[Daily Trust] Sokoto -Twenty children have died of measles out of the over 300 cases of the disease recorded in Sokoto State, the Executive Secretary of the state's Primary Healthcare Development Agency, Dr Sani Labaran, said yesterday. (Source: AllAfrica News: Health and Medicine)



Measles: A Canary in the Coal Mines?

Thu, 25 Feb 2016 19:34:54 +0100

(Source: Indian Journal of Pediatrics)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.




Comparison of the immunogenicity and safety of pentavalent vaccine Quinvaxem in a compact prefilled auto-disabled (cPAD) injection system versus single-dose vials in healthy infants: a phase 3, open-label, randomized, parallel-group, non-inferiority study

Thu, 25 Feb 2016 00:00:00 +0100

Immunization is a cost-effective and life-saving intervention that prevents an estimated two to three million deaths every year from vaccine-preventable diseases.1,2 The aim of the World Health Organization (WHO) Expanded Programme on Immunization (EPI) is to protect children against life-threatening diseases like tuberculosis, diphtheria, neonatal tetanus, whooping cough, poliomyelitis, and measles, as well as hepatitis B3 and Haemophilus influenzae type b (Hib).4 According to the WHO, approximately 22.6 million children worldwide did not receive the full three doses of diphtheria–tetanus–pertussis (DTP3) vaccine in 2012. (Source: International Journal of Infectious Diseases)



Post-vaccination MDEM associated with MOG antibody in a subclinical infected boy

Wed, 24 Feb 2016 00:00:00 +0100

In this report, we describe the case of a 6-year-old Japanese boy who had multiphasic disseminated encephalomyelitis (MDEM), and was positive for both anti-myelin oligodendrocyte glycoprotein (MOG) antibodies and Chlamydophila pneumoniae antibodies. After vaccinations that were the second one for measles and rubella, and the booster immunization for Japanese encephalitis, the patient presented with fever, headache, vomiting, and a change in personality. (Source: Brain and Development)



Post-vaccination MDEM associated with MOG antibody in a subclinical Chlamydia infected boy

Wed, 24 Feb 2016 00:00:00 +0100

In this report, we describe the case of a 6-year-old Japanese boy who had multiphasic disseminated encephalomyelitis (MDEM), and was positive for both anti-myelin oligodendrocyte glycoprotein (MOG) antibodies and Chlamydophila pneumoniae antibodies. After vaccinations that were the second one for measles and rubella, and the booster immunization for Japanese encephalitis, the patient presented with fever, headache, vomiting, and a change in personality. (Source: Brain and Development)



Understanding a role of folliculotropic viral infections in the pathogenesis of psoriasis

Sun, 21 Feb 2016 00:00:00 +0100

The renewed interest for focal infections in pathogenesis of psoriasis [1,2], prompted us to some considerations about viral infections with particular follicular tropism. Varicella-zoster (VZV) and measles are good examples of folliculotropic viral infections. VZV is among the most prevalent viruses affecting the human race and measles persists despite widespread use of vaccine and remains endemic in any country resulting occasionally in local outbreaks. (Source: Medical Hypotheses)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.




Current views and advances on Paediatric Virology: An update for paediatric trainees.

Sat, 20 Feb 2016 10:15:03 +0100

Authors: Mammas IN, Greenough A, Theodoridou M, Kramvis A, Christaki I, Koutsaftiki C, Koutsaki M, Portaliou DM, Kostagianni G, Panagopoulou P, Sourvinos G, Spandidos DA Abstract Paediatric Virology is a bold new scientific field, which combines Paediatrics with Virology, Epidemiology, Molecular Medicine, Evidence-based Medicine, Clinical Governance, Quality Improvement, Pharmacology and Immunology. The Workshop on Paediatric Virology, which took place on Saturday October 10, 2015 in Athens, Greece, provided an overview of recent views and advances on viral infections occurring in neonates and children. It was included in the official programme of the 20th World Congress on Advances in Oncology and the 18th International Symposium on Molecular Medicine, which attracted over 500 del...



Immunization Innovations: Improving Post-Transplant Vaccination Rates

Fri, 19 Feb 2016 10:35:12 +0100

The recent increased incidence of preventable communicable diseases has compromised “herd immunity”1 and places immunocompromised patients at increased risk of infection and mortality. The Centers for Disease Control reported over 600 cases of measles and 32,000 cases of pertussis in the United States in 20142, making post-transplant vaccination more important than ever before. (Source: Biology of Blood and Marrow Transplantation)



'Do not resist, show me your body!': Encounters Between the Jarwas of the Andamans and Medicine (1858-2004).

Fri, 19 Feb 2016 07:46:02 +0100

Authors: Pandya V Abstract Based on fieldwork and archival studies carried out since 1995, this paper is an analysis of the dialogue between the Jarwas and the outside world. The Jarwa tribal community on the Andaman Islands has a long history of voluntary isolation and pronounced hostility towards outsiders. This situation only started to change in the mid-1990s, when a young Jarwa was successfully treated at a local hospital. The Jarwas' sudden fascination with modern medicine was less to do with its therapeutic powers than the fact that, on each visit, hospital staff gave them food, clothes, and various consumer items. This paper describes events in the Jarwas' 'junket to modernity'. Before discussing recent events, the paper first retraces the history of relations between the J...



Development of the World Health Organization Measles Programmatic Risk Assessment Tool Using Experience from the 2009 Measles Outbreak in Namibia

Fri, 19 Feb 2016 00:00:00 +0100

This article provides a description of pilot testing of the tool in Namibia using comparisons of high‐risk districts identified using 2006–2008 data with reported measles cases and incidence during the 2009 outbreak. Of the 34 health districts in Namibia, 11 (32%) were classified as high risk or very high risk, including the district of Engela where the outbreak began in 2009. The district of Windhoek, including the capital city of Windhoek, had the highest overall risk score—driven primarily by poor population immunity and immunization program performance—and one of the highest incidences during the outbreak. Other high‐risk districts were either around the capital district or in the northern part of the country near the border with Angola. Districts categorized as high or very ...



Use of rapid needs assessment as a tool to identify vaccination delays in Guatemala and Peru.

Fri, 19 Feb 2016 00:00:00 +0100

CONCLUSIONS: RNA is a fast and effective method to identify timely vaccine coverage and derive a hypothesis of factors possibly associated with vaccination delay. PMID: 26902545 [PubMed - as supplied by publisher] (Source: Vaccine)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.




Isolation of vaccine-derived measles and rubella viruses, not as pathogens but by chance, from children with acute respiratory infections.

Fri, 19 Feb 2016 00:00:00 +0100

Authors: Aoki Y, Matoba Y, Tanaka S, Yahagi K, Ito S, Yoshida H, Itagaki T, Mizuta K PMID: 26902222 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)



World Health Organization responds to growing health needs in Yemen, calls for increased access

Thu, 18 Feb 2016 09:16:04 +0100

17 February 2016 Despite facing significant challenges as a result of the ongoing conflict in Yemen, WHO continues to respond to the increasing health needs of millions of people across the country. Since the beginning of the crisis, WHO has reached more than seven million people in 23 governorates through the provision of medicines, medical supplies, mobile medical teams and mobile clinics. More than five million children below the age of five have been vaccinated against polio, measles and rubella by WHO and partners. WHO has also provided more than 19 million litres of safe water and one million litres of fuel to health facilities and camps hosting internally displaced persons. In Taiz governorate, where hundreds of thousands of people are virtually cut off from humanitarian aid, WHO h...



Postexposure Management of Vaccine-Preventable Diseases

Thu, 18 Feb 2016 02:08:54 +0100

Because some parents are choosing to not vaccinate or only partially vaccinate their children, vaccine-preventable diseases that once were rarely seen in pediatric practice must now be considered part of the differential diagnosis when caring for these children. Measles, mumps, varicella, meningococcal disease, pertussis, and influenza are reviewed. Recommendations for prevention and treatment of these vaccine-preventable diseases are discussed. (Source: Journal of Pediatric Health Care)



Anti-infectious human vaccination in historical perspective.

Wed, 17 Feb 2016 14:23:02 +0100

Authors: D'Amelio E, Salemi S, D'Amelio R Abstract A brief history of vaccination is presented since the Jenner's observation, through the first golden age of vaccinology (from Pasteur's era to 1938), the second golden age (from 1940 to 1970), until the current period. In the first golden age, live, such as Bacille Calmette Guérin (BCG), and yellow fever, inactivated, such as typhoid, cholera, plague, and influenza, and subunit vaccines, such as tetanus and diphtheria toxoids, have been developed. In the second golden age, the cell culture technology enabled polio, measles, mumps, and rubella vaccines be developed. In the era of modern vaccines, in addition to the conjugate polysaccharide, hepatitis A, oral typhoid, and varicella vaccines, the advent of molecular biology enabled t...



Measles virus nucleocapsid protein increases osteoblast differentiation in Paget’s disease

Tue, 16 Feb 2016 22:19:01 +0100

Paget’s disease (PD) is characterized by focal and dramatic bone resorption and formation. Treatments that target osteoclasts (OCLs) block both pagetic bone resorption and formation; therefore, PD offers key insights into mechanisms that couple bone resorption and formation. Here, we evaluated OCLs from 3 patients with PD and determined that measles virus nucleocapsid protein (MVNP) was expressed in 70% of these OCLs. Moreover, transgenic mice with OCL-specific expression of MVNP (MVNP mice) developed PD-like bone lesions that required MVNP-dependent induction of high IL-6 expression levels in OCLs. In contrast, mice harboring a knockin of p62P394L (p62-KI mice), which is the most frequent PD-associated mutation, exhibited increased bone resorption, but not formation. Evaluation of OCLs ...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.




Molecular Characterization of Wild Type Measles Virus from Adult Patients in Northern China, 2014

Tue, 16 Feb 2016 00:00:00 +0100

(Source: International Journal of Infectious Diseases)



What Sunglasses in New York and Vaccines Have in Common

Mon, 15 Feb 2016 22:16:08 +0100

Vaccines and autism are in the news... again. This time, Melinda Gates' recent remarks at Davos got me thinking about a strange vaccines analogy. Often, the lack of widespread vaccinations leads to unsettling news headlines. As an example from 2014, a record high number of measles cases (667) was uncovered since the disease was considered eliminated in 2000. This did not transpire in one of the African countries that the Gates Foundation targets for funding vaccine campaigns, but in one of the most developed countries in the world and in the history of time. Before I demystify my analogy, let me ask a question: How can a celebrity hide in plain sight in a place you normally don't find them? Let's say in downtown Berkeley, California where I went to college, a colorful place where tight-jea...



Mitigating measles outbreaks in West Africa post-Ebola.

Sun, 14 Feb 2016 16:32:09 +0100

Authors: Truelove SA, Moss WJ, Lessler J Abstract The Ebola outbreak in 2014-2015 devastated the populations, economies and healthcare systems of Guinea, Liberia and Sierra Leone. With this devastation comes the impending threat of outbreaks of other infectious diseases like measles. Strategies for mitigating these risks must include both prevention, through vaccination, and case detection and management, focused on surveillance, diagnosis and appropriate clinical care and case management. With the high transmissibility of measles virus, small-scale reactive vaccinations will be essential to extinguish focal outbreaks, while national vaccination campaigns are needed to guarantee vaccination coverage targets are reached in the long term. Rapid and multifaceted strategies should care...