Subscribe: MedWorm: Environmental Health
Preview: MedWorm: Environmental Health

MedWorm: Environmental Health provides a medical RSS filtering service. Over 7000 RSS medical sources are combined and output via different filters. This feed contains the latest news and research in Environmental Health

Last Build Date: Mon, 28 Mar 2016 04:14:15 +0100


See How Oil Drilling Created an Earthquake Crisis in Oklahoma

Sun, 27 Mar 2016 16:00:35 +0100

In the last few years, Oklahoma has become one of the most seismic places on the planet. Last year, there were almost 6,000 earthquakes, 900 of which were magnitude 3 or higher, according to the U.S. Geological Survey (USGS). Scientists say the increase is due to hundreds of saltwater disposal wells around the state that pump brackish water that comes up naturally during drilling back underground. The state’s quakes have become so frequent that the USGS will release a new nationwide hazard map Monday which will, for the first time, include manmade earthquakes and show parts of Oklahoma to be as seismic as California. See how oil drilling causes earthquakes in the video above, and read more about it here. (Source: Top Science and Health Stories)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

Exposure to hand-arm vibrations in orthopaedic plaster room: risk management.

Sun, 27 Mar 2016 15:04:02 +0100

CONCLUSIONS: The values of acceleration and noise detected on the instruments  were  in line with those reported in the literature. The preventive measure adopted (replacing plaster saws currently used in the hospital with similar ones with lower vibration emission) was an adequate means of protection. Health surveillance activities  recorded a higher level of wellbeing, both environmentally and individually and, specifically, an increased protection level for the hyper-susceptibility conditions observed during health checks of exposed personnel  which will be monitored regularly by the Occupational Health Service. PMID: 27015026 [PubMed - as supplied by publisher] (Source: Medicina del Lavoro)

Occupational asthma in a fruit and vegetables vendor.

Sun, 27 Mar 2016 15:04:02 +0100

CONCLUSIONS: The clinical history and the results of the allergologic investigations, plus an on-the-spot inspection, permitted us to ascertain that this subject had developed occupational asthma due to Pleurotus ostreatus spores. We advised her to stop handling and selling mushrooms, and she has no longer suffered asthmatic symptoms, over seven years of follow-up, and regularly continued to work without needing to take anti-asthma drugs. PMID: 27015024 [PubMed - as supplied by publisher] (Source: Medicina del Lavoro)

The retinoblastoma protein regulates hypoxia-inducible genetic programs, tumor cell invasiveness and neuroendocrine differentiation in prostate cancer cells.

Sun, 27 Mar 2016 05:28:02 +0100

In this report, we further characterized the role Rb plays in mediating hypoxia-regulated genetic programs by stably ablating Rb expression with retrovirally-introduced short hairpin RNA in LNCaP and 22Rv1 human prostate cancer cells. DNA microarray analysis revealed that loss of Rb in conjunction with hypoxia leads to aberrant expression of hypoxia-regulated genetic programs that increase cell invasion and promote neuroendocrine differentiation. For the first time, we have established a direct link between hypoxic tumor environments, Rb inactivation and progression to late stage metastatic neuroendocrine prostate cancer. Understanding the molecular pathways responsible for progression of benign prostate tumors to metastasized and lethal forms will aid in the development of more effective ...

Antimicrobial resistance in faecal Escherichia coli isolates from farmed red deer and wild small mammals. Detection of a multiresistant E. coli producing extended-spectrum beta-lactamase.

Sun, 27 Mar 2016 05:20:02 +0100

Authors: Alonso CA, González-Barrio D, Tenorio C, Ruiz-Fons F, Torres C Abstract Eighty-nine Escherichia coli isolates recovered from faeces of red deer and small mammals, cohabiting the same area, were analyzed to determine the prevalence and mechanisms of antimicrobial resistance and molecular typing. Antimicrobial resistance was detected in 6.7% of isolates, with resistances to tetracycline and quinolones being the most common. An E. coli strain carrying blaCTX-M-1 as well as other antibiotic resistant genes included in an unusual class 1 integron (Intl1-dfrA16-blaPSE-1-aadA2-cmlA1-aadA1-qacH-IS440-sul3-orf1-mef(B)Δ-IS26) was isolated from a deer. The blaCTX-M-1 gene was transferred by conjugation and transconjugants also acquired an IncN plasmid. This strain was typed as ST22...

Quality Issues of Research Antibodies.

Sun, 27 Mar 2016 04:42:02 +0100

This article tries to consolidate the remarkable variety of conclusions and suggested activities into a more coherent conception. It is concluded that funding agencies and journal publishers need to take first and immediate measures to resolve these problems and lead the way to a more sustainable way of bioanalytical research, on which all can rely with confidence. PMID: 27013861 [PubMed] (Source: Analytical Chemistry Insights)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

Regulation of signaling events involved in the pathophysiology of neovascular AMD.

Sun, 27 Mar 2016 01:44:02 +0100

Authors: Wang H, Hartnett ME Abstract Neovascular age-related macular degeneration (AMD) is a complex disease in which an individual's genetic predisposition is affected by aging and environmental stresses, which trigger signaling pathways involving inflammation, oxidation, and/or angiogenesis in the RPE cells and choroidal endothelial cells (CECs), to lead to vision loss from choroidal neovascularization. Antiangiogenic therapies have greatly improved clinical outcomes in the last decade; however, vision improves in less than half of patients treated for neovascular AMD, and treatments remain inadequate for atrophic AMD. Many studies focus on genetic predisposition or the association of outcomes in trials of human neovascular AMD but are unable to evaluate the effects between diff...

Scientists fly glacial ice to south pole to unlock secrets of global warming

Sun, 27 Mar 2016 00:03:01 +0100

High on Mont Blanc, huge ice cores are being extracted to help researchers study the alarming rate of glacial meltIn a few weeks, researchers will begin work on a remarkable scientific project. They will drill deep into the Col du Dôme glacier on Mont Blanc and remove a 130 metre core of ice. Then they will fly it, in sections, by helicopter to a laboratory in Grenoble before shipping it to Antarctica. There the ice core will be placed in a specially constructed vault at the French-Italian Concordia research base, 1,000 miles from the south pole.The Col du Dôme ice will become the first of several dozen other cores, extracted from glaciers around the world, that will be added to the repository over the next few years. The idea of importing ice to the south pole may seem odd – the polar...

Water resistant reactive microcapsules for self-healing coatings in harsh environments

Sat, 26 Mar 2016 23:00:00 +0100

Publication date: 17 May 2016 Source:Polymer, Volume 91 Author(s): Dawei Sun, He Zhang, Xiu-Zhi Tang, Jinglei Yang Double-shelled microcapsules containing liquid 4,4′-bis-methylene cyclohexane diisocyanate (HMDI) with outstanding water resistance are successfully synthesized via combination of interfacial and in-situ polymerization reactions in an oil-in-water emulsion. The diameter and shell thickness of microcapsules increased under lower agitation rate. The relative residue of core content of microcapsules remains more than 90% after 24 days in both ambient open air and water. Manually scratched polymer coatings with both fresh and conditioned microcapsules showed satisfactory anticorrosion performance in salt water via self-healing functionality. In addition, self-healing coati...

Increased resistance to detachment of adherent microspheres and Bacillus spores subjected to a drying step

Sat, 26 Mar 2016 23:00:00 +0100

In this study, we investigated the consequences of a drying step on the further ability of adherent bacterial spores to resist detachment. An initial series of experiment was set up with latex microspheres as a model. A microsphere suspension was deposited on a glass slide and incubated at 25, 35 and 50°C for times ranging from 1h to 48h. By subjecting the dried slides to increasing water flow rates, we showed that both time and temperature affected the ease of microsphere detachment. Similar observations were made for three Bacillus spores despite differences in their surface properties, especially regarding their surface physicochemistry. The differences in ease of adherent spore detachment could not be clearly linked to the minor changes in spore morphology, observed after drying in va...

The relationship of bone-tumor-induced spinal cord astrocyte activation and aromatase expression to mechanical hyperalgesia and cold hypersensitivity in intact female and ovariectomized mice

Sat, 26 Mar 2016 23:00:00 +0100

Publication date: 2 June 2016 Source:Neuroscience, Volume 324 Author(s): B.A. Smeester, E.E. O’Brien, K.S. Michlitsch, J.-H. Lee, A.J. Beitz Recently, our group established a relationship between tumor-induced spinal cord astrocyte activation and aromatase expression and the development of bone tumor nociception in male mice. As an extension of this work, we now report on the association of tumor-induced mechanical hyperalgesia and cold hypersensitivity to changes in spinal cord dorsal horn GFAP and aromatase expression in intact (INT) female mice and the effect of ovariectomy on these parameters. Implantation of fibrosarcoma cells produced robust mechanical hyperalgesia in INT animals, while ovariectomized (OVX) females had significantly less mechanical hyperalgesia. Cold hyperse...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

Link Adaptive One-Way Decode and Forward (DF) Relaying With Orthogonal Frequency Division Multiplexing (OFDM)

Sat, 26 Mar 2016 23:00:00 +0100

Publication date: 2016 Source:Materials Today: Proceedings, Volume 3, Issue 5 Author(s): Mete Yildirim, Hacı İlhan In this paper, link adaptive one-way decode and forward (DF) relaying with Orthogonal Frequency Division Multiplexing (OFDM) is proposed. The relay, in the proposed system, adapts the power level of each sub-carrier according to power scaling factor which is obtained from source-relay and relay-destination fading parameters. The fading parameters are assumed to have Nakagami-m distribution. The link adaptive system is compared to the non-link adaptive one in multi-carrier transmission. To reach concrete results, the performance of the considered system is examined for various link adaptive factors, and it is shown that the proposed system achieves better bit error rate (...

Individualized Household Allergen Intervention Lowers Allergen Level But Not Asthma Medication use: A Randomized Controlled Trial

Sat, 26 Mar 2016 23:00:00 +0100

Conclusions Targeted allergen avoidance measures do not allow for reduction in asthma pharmacologic therapy compared with usual care in patients already receiving optimal controller therapy. (Source: The Journal of Allergy and Clinical Immunology: In Practice)

Heterogeneity in individual adaptation action: Modelling the provision of a climate adaptation public good in an empirically grounded synthetic population

Sat, 26 Mar 2016 23:00:00 +0100

Publication date: Available online 26 March 2016 Source:Journal of Environmental Psychology Author(s): Friedrich Krebs Adaptation to climate change depends to a significant extent on behavioural change in the form of individual adaptation action. We investigate the case of urban neighbourhood activation for the support of the elderly during the more likely occurring extreme heat waves generated by climate change. The proposed integrative theoretical consideration makes on the one hand reference to social dilemma theory and on the other to concepts from behavioural theory and social psychology. The case context is particularly challenging because it involves intra-individual dynamics of psychological processes, inter-individual dynamics of social influence and environmental dynamics gove...

Activity-dependent plasticity in the isolated embryonic avian brainstem following manipulations of rhythmic spontaneous neural activity

Sat, 26 Mar 2016 23:00:00 +0100

Publication date: Available online 26 March 2016 Source:Respiratory Physiology & Neurobiology Author(s): Michael A. Vincen-Brown, Ann L. Revill, Jason Q. Pilarski When rhythmic spontaneous neural activity (rSNA) first appears in the embryonic chick brainstem and cranial nerve motor axons it is principally driven by nicotinic neurotransmission (NT). At this early age, the nicotinic acetylcholine receptor (nAChR) agonist nicotine is known to critically disrupt rSNA at low concentrations (0.1-0.5μM), which are levels that mimic the blood plasma levels of a fetus following maternal cigarette smoking. Thus, we quantified the effect of persistent exposure to exogenous nicotine on rSNA using an in vitro developmental model. We found that rSNA was eliminated by continuous bath applic...

Measuring Infrastructure: A Key Step in Program Evaluation and Planning

Sat, 26 Mar 2016 23:00:00 +0100

Publication date: Available online 26 March 2016 Source:Evaluation and Program Planning Author(s): Carol L. Schmitt, LaShawn Glasgow, S. Rene Lavinghouze, Patricia P. Rieker, Erika Fulmer, Kelly McAleer, Todd Rogers State tobacco prevention and control programs (TCPs) require a fully functioning infrastructure to respond effectively to the Surgeon General’s call for accelerating the national reduction in tobacco use. The literature describes common elements of infrastructure; however, a lack of valid and reliable measures has made it difficult for program planners to monitor relevant infrastructure indicators and address observed deficiencies, or for evaluators to determine the association among infrastructure, program efforts, and program outcomes. The Component Model of Infras...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

Evaluation of the RBC Pig-a assay and the PIGRET assay using benzo[a]pyrene in rats

Sat, 26 Mar 2016 23:00:00 +0100

Publication date: Available online 26 March 2016 Source:Mutation Research/Genetic Toxicology and Environmental Mutagenesis Author(s): Ryuta Kikuzuki, Haruka Sato, Ai Fujiwara, Tomoko Takahashi, Yosuke Ogiwara, Mihoko Sugiura The red blood cell (RBC) Pig-a assay has the potential to detect the in vivo mutagenicity of chemicals. Recently, use of the Pig-a assay with reticulocytes (the PIGRET assay) reportedly enabled the in vivo mutagenicity of chemicals to be detected earlier than using the RBC Pig-a assay. To evaluate whether the PIGRET assay is useful and effective as a short-term test, compared with the RBC Pig-a assay, we performed both assays using benzo[a]pyrene (BP), which is a well-known mutagen. BP was used to dose 8-week-old male rats orally at 0, 75.0, 150, and 300mg/kg a...

A Model For Sea Lice (Lepeophtheirus salmonis) Dynamics In A Seasonally Changing Environment

Sat, 26 Mar 2016 23:00:00 +0100

Publication date: Available online 26 March 2016 Source:Epidemics Author(s): Matthew A. Rittenhouse, Crawford W. Revie, Amy Hurford Sea lice (Lepeophtheirus salmonis) are a significant source of monetary losses on salmon farms. Sea lice exhibit temperature-dependent development rates and salinity-dependent mortality, but to date no deterministic models have incorporated these seasonally varying factors. To understand how environmental variation and life history characteristics affect sea lice abundance, we derive a delay differential equation model and parameterize the model with environmental data from British Columbia and southern Newfoundland. We calculate the lifetime reproductive output for female sea lice maturing to adulthood at different times of the year and find differences ...

Deoxynivalenol inhibits proliferation and induces apoptosis in human umbilical vein endothelial cells

Sat, 26 Mar 2016 23:00:00 +0100

In this study, we investigated the toxic and apoptotic effects of DON in human umbilical vein endothelial cells (HUVECs), a good model for studying inflammation. The results show that DON significantly inhibited the viability of HUVECs. DON could also inhibit the proliferation of HUVECs through G2/M phase arrest in cell cycle progression. Moreover, oxidative stress induced by DON was indicated by observations of increased levels of reactive oxygen species (ROS). In addition, DON also causes mitochondrial damage by decreasing the mitochondrial membrane potential and inducing apoptosis by up-regulation of apoptosis-related genes like caspase-3, caspase-9, and Bax genes, and down-regulation of Bcl-2 gene. These results together suggest that DON could induce cell cycle arrest, oxidative stress...

Nonylphenol-induced Hyperadrenalism Can Be Reversed/Alleviated by Inhibiting of 11-β Hydroxysteroid Dehydrogenase Type 1

Sat, 26 Mar 2016 23:00:00 +0100

This study examined the effect of PF915275 (a selective 11β-HSD1 inhibitor) on hyperadrenalism and adipogenesis in male rats exposed to NP during development. The results showed that treatment with the 11β-HSD1 inhibitor PF915275 reversed/alleviated NP-induced hyperadrenalism via the following mechanisms: (1) decreasing serum corticosterone, 11β-hydroxylase, and aldosterone synthase levels; (2) significantly increasing PPARα protein and mRNA expression. In adipose tissue, NP significantly increased PPARγ mRNA expression, whereas PF915275 significantly decreased the level of mRNA expression; and (3) the expression of key regulators/enzymes in the adipogenesis metabolic pathway was also modulated. (Source: Environmental Toxicology and Pharmacology)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

Fas ligand based immunotherapy: A potent and effective neoadjuvant with checkpoint inhibitor properties, or a systemically toxic promoter of tumor growth?

Sat, 26 Mar 2016 21:34:04 +0100

Authors: Modiano JF, Bellgrau D Abstract Fas ligand (FasL, CD95L) is a 40-kDa type II transmembrane protein that binds to Fas (CD95) receptors and promotes programmed cell death. Fas receptors are expressed at higher levels in many tumors than in normal cells; however, systemic administration of FasL or agonistic anti-Fas antibodies to mice with tumors caused lethal hepatitis. Somewhat paradoxically, elimination of Fas or FasL from tumors also leads to death induced by CD95 receptor/ligand elimination (DICE). At face value, this suggests that Fas signaling not only kills normal cells, but that it also is essential for tumor cell survival. Targeting this pathway may not only fail to kill tumors, but instead may even enhance their growth, leading some to report the demise of Fas liga...

Eastern Monarch Butterflies May Be At Risk Of Extinction Within 20 Years

Sat, 26 Mar 2016 20:51:30 +0100

North America’s eastern monarch butterflies may still be at risk of extinction, despite recent increases in their population. The population of eastern monarchs has declined 84 percent from the winter of 1996-1997 to the winter of 2014-1015, according to a Scripps Institution of Oceanography study. (Western monarch butterflies, which live west of the Rocky Mountains and migrate to California, were not included in the study. However, other studies indicate they are experiencing population declines of their own.) This long-term decline means there is a “substantial chance” that monarchs become “quasi-extinct” within the next 20 years, researchers wrote in the study, published Monday in in the journal Scientific Reports. This means that a spec...

Sustained release of neurotrophin‐3 via calcium phosphate‐coated sutures promotes axonal regeneration after spinal cord injury

Sat, 26 Mar 2016 20:22:17 +0100

This study uses peripheral nerve grafts (PNGs) as scaffolds for axonal growth while delivering neurotrophin‐3 (NT‐3) via calcium phosphate (CaP) coatings on surgical sutures. CaP coating was grown on sutures, and NT‐3 binding and release were characterized in vitro. Then, the NT‐3‐loaded sutures were tested in a complete SCI model. Rats were analyzed for functional improvement and axonal growth into the grafts. The CaP‐coated sutures exhibited a burst release of NT‐3, followed by a sustained release for at least 20 days. Functionally, the rats with PNGs + NT‐3‐loaded sutures and the rats treated with PNGs scored significantly higher than controls on day 56 postoperatively. However, functional scores in rats treated with PNGs + NT‐3‐loaded suture were not signi...

Spatial data warehouses and spatial OLAP come towards the cloud: design and performance

Sat, 26 Mar 2016 15:07:09 +0100

Abstract Cloud computing systems handle large volumes of data by using almost unlimited computational resources, while spatial data warehouses (SDWs) are multidimensional databases that store huge volumes of both spatial data and conventional data. Cloud computing environments have been considered adequate to host voluminous databases, process analytical workloads and deliver database as a service, while spatial online analytical processing (spatial OLAP) queries issued over SDWs are intrinsically analytical. However, hosting a SDW in the cloud and processing spatial OLAP queries over such database impose novel obstacles. In this article, we introduce novel concepts as cloud SDW and spatial OLAP as a service, and afterwards detail the design of novel schemas for cloud SDW and spa...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

Chronos: a NoSQL system on flash memory for industrial process data

Sat, 26 Mar 2016 15:07:09 +0100

Abstract Within Électricité de France (EDF) hydroelectric power stations, IGCBoxes are industrial mini PCs dedicated to industrial process data archiving. These equipments expose distinctive features, mainly on their storage system based exclusively on flash memory due to environmental constraints. This type of memory had notable consequences on data acquisition performance, with a substantial drop compared with hard disk drives. In this setting, we have designed Chronos, an open-source NoSQL system for sensor data management on flash memories. Chronos includes an efficient quasi-sequential write pattern along with an index management technique adapted for process data management. As a result, Chronos supports a higher velocity for inserted data, with acquisition rates improved...

Photokeratitis Linked to Metal Halide Bulbs in Two Gymnasiums - Philadelphia, Pennsylvania, 2011 and 2013.

Sat, 26 Mar 2016 14:09:02 +0100

Authors: Finn LE, Gutowski J, Alles S, Mirowitz N, Johnson C, Osterhoudt KC, Patel A Abstract In December 2011 and December 2013, the Philadelphia Department of Public Health (PDPH) received separate reports of clusters of photokeratitis linked to gymnasium events. Photokeratitis, a painful eye condition resulting from unprotected exposure to ultraviolet radiation, has previously been linked to metal halide lamps with broken outer envelopes (1,2). To investigate the cause of these clusters and further characterize patients with photokeratitis, PDPH administered questionnaires to potentially exposed persons, established a case definition, and conducted environmental assessments of both gymnasiums. Because event attendee registration information was available, a cohort study was cond...

Environment-induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children.

Sat, 26 Mar 2016 11:56:02 +0100

Authors: Bauer T, Trump S, Ishaque N, Thürmann L, Gu L, Bauer M, Bieg M, Gu Z, Weichenhan D, Mallm JP, Röder S, Herberth G, Takada E, Mücke O, Winter M, Junge KM, Grützmann K, Rolle-Kampczyk U, Wang Q, Lawerenz C, Borte M, Polte T, Schlesner M, Schanne M, Wiemann S, Geörg C, Stunnenberg HG, Plass C, Rippe K, Mizuguchi J, Herrmann C, Eils R, Lehmann I Abstract Epigenetic mechanisms have emerged as links between prenatal environmental exposure and disease risk later in life. Here, we studied epigenetic changes associated with maternal smoking at base pair resolution by mappingDNAmethylation, histone modifications, and transcription in expectant mothers and their newborn children. We found extensive global differential methylation and carefully evaluated these changes to separate...

Road traffic accidents: patterns and predisposing factors - Prasanna VK, Vanaja D, Bellara R.

Sat, 26 Mar 2016 11:13:34 +0100

Background Road traffic accidents are multifactorial in nature which involves human, environmental factors and vehicular factors. The present study will help us to shed light into factors facilitating the occurrence of accidents. Objectives To st... (Source: SafetyLit)

Shock tubes and blast injury modeling - Ning YL, Zhou YG.

Sat, 26 Mar 2016 11:13:34 +0100

Explosive blast injury has become the most prevalent injury in recent military conflicts and terrorist attacks. The magnitude of this kind of polytrauma is complex due to the basic physics of blast and the surrounding environments. Therefore, development o... (Source: SafetyLit)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

A contrast study of the traumatic condition between the wounded in 5.12 Wenchuan earthquake and 4.25 Nepal earthquake - Ding S, Hu Y, Zhang Z, Wang T.

Sat, 26 Mar 2016 11:13:34 +0100

PURPOSE 5.12 Wenchuan earthquake and 4.25 Nepal earthquake are of the similar magnitude, but the climate and geographic environment are totally different. Our team carried out medical rescue in both disasters, so we would like to compare the different tra... (Source: SafetyLit)

Emergency medicine for disaster rescue - Wang ZG, Zhang L, Zhao WJ.

Sat, 26 Mar 2016 11:13:34 +0100

The word "disaster" refers to a sudden environmental megaevolution which causes casualties, property loss and ecological damage. Disaster is defined by the WHO as an event that causes facility damage, human casualties, worsening conditions of health and sa... (Source: SafetyLit)

Prediction of drivers' visual strategy using an analytical model - Bosurgi G, D’Andrea A, Pellegrino O.

Sat, 26 Mar 2016 11:13:34 +0100

The proposed research addresses the problem of predicting driver's visual behavior. Notably, this issue is of great importance for road safety because it provides information about the true perception of the road environment. This need is particularly felt... (Source: SafetyLit)

Development of composite road environment safety index - Hussain H, Suhana MRI, Law TH, farhan MSA.

Sat, 26 Mar 2016 11:13:34 +0100

This study aims to develop a road safety index that combines selected road environmental characteristics in Malaysia. Firstly, 14 indicators that generally portray the Malaysian road environments were selected. Then, the final list of specific indicators f... (Source: SafetyLit)

The Effect of Intermittent Arm and Shoulder Cooling on Baseball Pitching Velocity

Sat, 26 Mar 2016 10:25:17 +0100

This study investigated the effects of intermittent cryotherapy on pitching velocity and subjective measures of recovery and exertion in a simulated baseball game. Trained college-aged male baseball pitchers (n = 8) threw 12 pitches (1 pitch every 20 seconds) per inning for 5 total innings during a simulated pitching start. Between each inning, pitchers received shoulder and arm cooling (AC) or, on a separate occasion, no cooling (NC). All sessions took place in a temperate environment (18.3 ± 2.8° C; 49 ± 4% relative humidity). Pitch speeds were averaged for each participant each inning and overall for 5 innings. Perceived exertion (rating of perceived exertion [RPE]) was recorded at the end of each simulated inning. Perceived recovery (perceived recovery scale [PRS]) was recorded afte...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

Acute Pneumonia

Sat, 26 Mar 2016 07:44:23 +0100

Acute pneumonia is an active infection of the lungs that results when an individual at risk gets exposed to a particular microbiological pathogen. Acute pneumonia is the leading cause of death in the United States that is attributable to an infection. The risk factors, pathogenesis, and microbiological organisms involved differ if the pneumonia develops in the community versus health care-associated environment. The development of concise and comprehensive guidelines has led to an improvement in the management of the problem. However, the emergence of multidrug-resistant organisms and the increase in the percentage of elderly population keep mortality risk very substantial. (Source: Critical Care Nursing Quarterly)

EPA spends nearly $300k to track energy and water use of office workers while doing nothing about children drinking lead-laced water

Sat, 26 Mar 2016 06:00:00 +0100

(NaturalNews) While lead-laden water has destroyed the lives of many U.S. residents, the Environmental Protection Agency (EPA) has remained disturbingly hands-off in the matter, if not ignoring the problem entirely.One case where their disregard for human safety is evident involves... (Source:

Climate vs. Primate: Dawn of Extinction?

Sat, 26 Mar 2016 03:52:00 +0100

A new study finds that every single primate species will be adversely affected by rising temperatures and changing rainfall levels -- Read more on (Source: Scientific American)

Weekend Roundup: Between Engagement and Terror

Sat, 26 Mar 2016 02:39:56 +0100

This week we witnessed a world coming together and a world falling apart, a world between engagement and terror. For the first time in nearly 90 years, an American president visited Cuba, turning upside down the anti-Yanqui narrative that has been the raison d'être of one of the Western Hemisphere's most longest-lasting dictatorships. In Havana, President Barack Obama promised to work toward lifting the embargo on Cuba just as he has done in Iran, where the advance of reformists in last month's election has already demonstrated the fruits of that opening. In Brussels, it appears that some children of Muslim immigrants expressed their explosive alienation in terror attacks in the very city many of them grew up, which also happens to be the capital of Europe. As the French scholar Olivier ...

The 5 Best Remedies For Sinus Problems

Sat, 26 Mar 2016 01:42:43 +0100

SPECIAL FROM Here’s an appetizing tidbit: Your sinus produces one to two liters of mucus every day—that’s the size of two large soda bottles. Under normal conditions, most of the mucus dribbles undetected down your throat. Yes, it’s gross but also very important: Mucus filters out bacteria, viruses, and fungi in the air that we breathe, and moistens the nasal passages and sinuses, allowing us to breathe easier and lessen risk of infections.  Sometimes, due to allergens, environmental pollution, nasal obstruction or inflammation, the system goes haywire, filling you with congestion. According to American Family Physician, “sinusitis is one of the most common conditions treated by primary care physicians. Each year in the United States, sinusitis affe...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

Autism and chromosome abnormalities – A Review

Sat, 26 Mar 2016 01:25:04 +0100

This article is protected by copyright. All rights reserved. (Source: Clinical Anatomy)

Flint task force report identifies failures

Sat, 26 Mar 2016 01:23:24 +0100

Government failed Flint at every single level and, in turn, shaped a "clear case" of environmental injustice against the majority African-American community, a task force commissioned by Michigan Gov. Rick Snyder to study the city's water crisis foun... (Source: - Health)

PMC: Public Access Expansion

Sat, 26 Mar 2016 00:50:11 +0100

From NLM: As of March 2015, the following additional agencies are using the NIH Manuscript Submission (NIHMS) system to facilitate the deposit in PMC of peer-reviewed manuscripts that fall under their public access policies: Centers for Disease Control and Prevention (CDC/HHS), Food and Drug Administration (FDA/HHS), National Institute of Standards and Technology (NIST), and U.S. Department of Veterans Affairs (VA) Additionally, the following additional HHS and other federal agencies have announced public access plans and have committed to using PMC as the repository for agency-funded publications: Administration for Community Living (ACL/HHS) Agency for Healthcare Research Quality (AHRQ/HHS) Assistant Secretary for Preparedness and Response (ASPR/HHS) Environmental Protection Agency (E...

Procedures to Assist Health Care Providers to Determine When Home Assessments for Potential Mold Exposure Are Warranted

Fri, 25 Mar 2016 23:00:00 +0100

We present the procedures in the form of a guided 2-part interview. The first part has 5 questions that triage the patient toward a more detailed questionnaire that reflects features of housing conditions known to be reliably associated with exposures to mold and dampness contaminants. We chose the questions based on the conditions associated with moisture problems in homes across the United States and Canada. The goal is to facilitate the clinician's effort to help patients reduce exposure to environmental triggers that elicit symptoms to better manage their disease. (Source: The Journal of Allergy and Clinical Immunology: In Practice)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

Occupational exposure to volatile anaesthetics: a systematic review

Fri, 25 Mar 2016 23:00:00 +0100

Conclusions Evidence for adverse effects of volatile anaesthetics on exposed personnel is scarce and inconsistent, but there is no evidence of adverse effects when environmental levels are kept within legal threshold values. Further studies are needed to improve our knowledge of the effects of occupational exposure to volatile anaesthetics. New surveillance methods that include systematic data collection, clinical signs and biomarkers of exposure are required to formulate consistent and reproducible surveillance criteria for exposed personnel. (Source: Occupational Medicine)

Decision-making in job attendance within health care--a qualitative study

Fri, 25 Mar 2016 23:00:00 +0100

Conclusions The findings highlight the complexity of managing work when experiencing musculoskeletal symptoms, and the dilemmas faced by those affected. The importance of work environment factors and the fact that some women feel compelled to work part-time in order to prioritize their own health require further consideration. (Source: Occupational Medicine)

Intraoperative application of hand-held structured light scanning: a feasibility study

Fri, 25 Mar 2016 23:00:00 +0100

Conclusions The results of this preliminary study indicate that structured light scanning could be applied accurately and safely in a surgical environment. This could result in a variety of applications for these scanners in image-guided interventions as intraoperative imaging and registration tools. (Source: International Journal of Computer Assisted Radiology and Surgery)

Variation in the abundance of Pseudo-nitzschia and domoic acid with surf zone type

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: May 2016 Source:Harmful Algae, Volume 55 Author(s): Alan L. Shanks, Steven G. Morgan, Jamie MacMahan, Ad J.H.M Reniers, Raphael Kudela, Marley Jarvis, Jenna Brown, Atsushi Fujimura, Lisa Ziccarelli, Chris Griesemer Most harmful algal blooms (HAB) originate away from the shore and, for them to endanger human health, they must be first transported to shore after which they must enter the surf zone where they can be feed upon by filter feeders. The last step in this sequence, entrance into the surf zone, depends on surf zone hydrodynamics. During two 30-day periods, we sampled Pseudo-nitzschia and particulate domoic acid (pDA) in and offshore of a more dissipative surf zone at Sand City, California (2010) and sampled Pseudo-nitzschia in and out of reflective surf...

Effects of the bloom of harmful benthic dinoflagellate Ostreopsis cf. ovata on the microphytobenthos community in the northern Adriatic Sea

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: May 2016 Source:Harmful Algae, Volume 55 Author(s): Stefano Accoroni, Tiziana Romagnoli, Salvatore Pichierri, Cecilia Totti Composition and temporal variation of the microphytobenthos communities of the Conero Riviera (northern Adriatic Sea) were investigated in the course of an annual cycle, focusing on their relationships with blooms of the benthic dinoflagellate Ostreopsis cf. ovata. Sampling was carried out from March 2009 to March 2010 on undisturbed benthic substrata (macroalgae and pebbles). Samples for the study of microphytobenthos were collected with a monthly frequency, while those for the study of Ostreopsis bloom weekly. Benthic diatoms dominated the microphytobenthos communities for most of the annual cycle (except the summer), both in terms of abundan...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

Ultrasensitive photoelectrochemical determination of chromium(VI) in water samples by ion-imprinted/formate anion-incorporated graphitic carbon nitride nanostructured hybrid

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: 15 July 2016 Source:Journal of Hazardous Materials, Volume 312 Author(s): Tian Fang, Xiaomin Yang, Lizhi Zhang, Jingming Gong A rapid and highly sensitive photoelectrochemical (PEC) method has been proposed for the determination of trace amounts of chromium in water samples under visible-light irradiation. Here, a unique nanostructured hybrid of formate anion incorporated graphitic carbon nitride (F-g-C3N4) is smartly integrated with a Cr(VI) ion-imprinted polymer (IIP) as a photoactive electrode (denoted as IIP@F-g-C3N4). The nanohybrid of F-g-C3N4 exhibits an enhanced charge separation with substantially improved PEC responses versus g-C3N4. The newly designed IIP@F-g-C3N4 PEC sensor exhibits high sensitivity and selectivity for the determination of Cr(VI) because...

Time-dependent effects of [apyr]BF4 and key contributors to their mixture stimulation on Vibrio qinghaiensis sp.-Q67 at apical and biochemical levels

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: 15 July 2016 Source:Journal of Hazardous Materials, Volume 312 Author(s): ZhenYang Yu, Jing Zhang Earlier reports studied the time-dependent effects of imidazolium-based ionic liquids ([amim]X) in the aspect of biochemical explanation and that of key contributor in mixture effects. Presently, the effects of N-alkylpyridinium-based ILs ([apyr]BF4) were studied combining the above two aspects, i.e., the time-dependent effects of [bpyr]BF4, [hpyr]BF4 and [opyr]BF4 on luminescence and biochemical indicators in Vibrio qinghaiensis sp.-Q67, and those of the mixtures. In individual results, the inhibition on luminescence increased over concentrations and the side chain length, showing concentration- and side chain-dependence. Moreover, the inhibition of [apyr]BF4 decreased f...

Synergistic effects of plant growth-promoting Neorhizobium huautlense T1-17 and immobilizers on the growth and heavy metal accumulation of edible tissues of hot pepper

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: 15 July 2016 Source:Journal of Hazardous Materials, Volume 312 Author(s): Ling Chen, Lin-yan He, Qi Wang, Xia-fang Sheng A plant growth-promoting Neorhizobium huautlense T1-17 was evaluated for its immobilization of Cd and Pb in solution. Meanwhile, the impacts of T1-17, immobilizers (vermiculite and peat) and their combination on the fruit biomass and heavy metal accumulation of hot pepper were characterized. T1-17 could significantly reduced water-soluble Cd and Pb in solution. T1-17, vermiculite+T1-17, peat, and peat+T1-17 significantly increased the fruit biomass (ranging from 45% to 269%) and decreased the fruit Cd (ranging from 66% to 87%) and Pb (ranging from 30% to 56%) contents and water-soluble Cd and Pb (ranging from 23% to 59%) contents of the rhizospher...

Molecular distribution and toxicity assessment of praseodymium by Spirodela polyrrhiza

Fri, 25 Mar 2016 23:00:00 +0100

In this study, the physiological, biochemical, and ultrastructural responses of Spirodela polyrrhiza to elevated concentrations of praseodymium (Pr), ranging from 0 to 60μM, were investigated over 20 d exposure. The results showed that the accumulation of Pr in S. polyrrhiza occurred in a concentration-dependent manner. The accumulation of Pr in biomacromolecules decreased in the order of cellulose and pectin (65–69%), crude proteins (18–25%), crude polysaccharides (6–10%), crude lipids (3%–4%). Significant increases in malondialdehyde (MDA), and decreases in photosynthetic pigment, soluble protein, and unsaturated fatty acids showed that Pr induced oxidative stress. Inhibitory effects on photosystem II and the degradation of the reaction center proteins D1 and D2 were revealed by...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

Using paired soil and house dust samples in an in vitro assay to assess the post ingestion bioaccessibility of sorbed fipronil

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: 15 July 2016 Source:Journal of Hazardous Materials, Volume 312 Author(s): James M. Starr, Weiwei Li, Stephen E. Graham, Karen D. Bradham, Daniel M. Stout II, Alan Williams, Jason Sylva For children, ingestion of soils and house dusts can be an important exposure pathway for regulated organic compounds. Following ingestion, the extent to which compounds desorb and become bioaccessible is a critical determinant of systemic adsorption. We characterized the physicochemical properties of 37 soil and house dust pairs collected during a national survey of United States homes. For each sample, we measured the bioaccessibility of fipronil, a phenylpyrazole insecticide using an in vitro, three- compartment digestive system, then modeled the physicochemical predictors of fi...

Nitrate removal from aqueous solution using granular chitosan-Fe(III)–Al(III) complex: Kinetic, isotherm and regeneration studies

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: Available online 25 March 2016 Source:Journal of the Taiwan Institute of Chemical Engineers Author(s): Qili Hu, Nan Chen, Chuanping Feng, Weiwu Hu, Jing Zhang, Hengyuan Liu, Qiaochong He In order to effectively remove nitrate from aqueous solution and reduce environmental and health risks caused by excess nitrate in natural water bodies, granular chitosan-Fe(III)-Al(III) complex was prepared through precipitation method and characterized using some techniques such as SEM, XRD, BET, FTIR and XPS. Adsorption performance was optimized by full factorial design. Kinetic and isotherm models were used to analyse experimental data, and reusability was also investigated. Adsorption mechanisms were primarily dominated by ion exchange and electrostatic attraction. pH and te...

Speciation analysis and fractionation of manganese: A review

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: June 2016 Source:TrAC Trends in Analytical Chemistry, Volume 80 Author(s): Emilia Grygo-Szymanko, Anna Tobiasz, Stanisław Walas Manganese as an essential element is required by organisms from simple bacteria to plants, animals and human beings. The identification and determination of organic or inorganic manganese forms are important from many viewpoints, such as their bioavailability or bioactivity. A review of the use of different analytical methods, which allow manganese speciation and fractionation in various types of matrices, such as soils, sediments, air, aerosols, water, plants, animals and polluted environmental samples, is presented in this study. The presented approaches assume mainly the use of indirect techniques from simple ones, such as extraction, th...

iTRAQ-based proteomic analysis reveals the mechanisms of silicon-mediated cadmium tolerance in rice (Oryza sativa) cells

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: July 2016 Source:Plant Physiology and Biochemistry, Volume 104 Author(s): Jie Ma, Huachun Sheng, Xiuli Li, Lijun Wang Silicon (Si) can alleviate cadmium (Cd) stress in rice (Oryza sativa) plants, however, the understanding of the molecular mechanisms at the single-cell level remains limited. To address these questions, we investigated suspension cells of rice cultured in the dark environment in the absence and presence of Si with either short- (12 h) or long-term (5 d) Cd treatments using a combination of isobaric tags for relative and absolute quantitation (iTRAQ), fluorescent staining, and inductively coupled plasma mass spectroscopy (ICP-MS). We identified 100 proteins differentially regulated by Si under the short- or long-term Cd stress. 70% of these proteins...

Phenolic compounds as indicators of drought resistance in shrubs from Patagonian shrublands (Argentina)

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: July 2016 Source:Plant Physiology and Biochemistry, Volume 104 Author(s): M. Celeste Varela, Idris Arslan, Mariana A. Reginato, Ana M. Cenzano, M. Virginia Luna Summary Plants exposed to drought stress, as usually occurs in Patagonian shrublands, have developed different strategies to avoid or tolerate the lack of water during their development. Production of phenolic compounds (or polyphenols) is one of the strategies used by some native species of adverse environments to avoid the oxidative damage caused by drought. In the present study the relationship between phenolic compounds content, water availability and oxidative damage were evaluated in two native shrubs: Larrea divaricata (evergreen) and Lycium chilense (deciduous) of Patagonian shrublands by their mean...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

Role of patulin in post-harvest diseases

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: Available online 24 March 2016 Source:Fungal Biology Reviews Author(s): Shiri Barad, Edward Sionov, Dov Prusky Storage of freshly harvested deciduous fruits is a key factor in modulating their supply for several months after harvest. Penicillium expansum is a post-harvest pathogen that colonises these fruit during storage, having penetrated the fruit through wounds incurred at harvest. The fungus macerates the host tissue during the long periods of storage and simultaneously accumulates significant amounts of the mycotoxin patulin. Fungal decay is a concern for both retailers and consumers, due to the presence of mycotoxins that may appear in fresh fruit as well in their derived products, and patulin levels are therefore monitored. Patulin is a toxic secondary metabo...

The response of mesophyll conductance to nitrogen and water availability differs between wheat genotypes.

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: Available online 25 March 2016 Source:Plant Science Author(s): Margaret M. Barbour, Brent N. Kaiser Increased mesophyll conductance (gm) has been suggested as a target for selection for high productivity and high water-use efficiency in crop plants, and genotypic variability in gm has been reported in several important crop species. However, effective selection requires an understanding of how gm varies with growth conditions, to ensure that the ranking of genotypes is consistent across environments. We assessed the genotypic variability in gm and other leaf gas exchange traits, as well as growth and biomass allocation for six wheat genotypes under different water and nitrogen availabilities. The wheat genotypes differed in their response of gm to growth conditions, r...

Insulin-like growth factor 1 (IGF-1) therapy: Mitochondrial dysfunction and diseases

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: Available online 25 March 2016 Source:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease Author(s): M.C. Sádaba, I. Martín-Estal, J.E. Puche, I. Castilla-Cortázar This review resumes the association between mitochondrial function and diseases, especially neurodegenerative diseases. Additionally, it summarizes the major role of IGF-1 as a mitochondrial protector, as studied in several experimental models (cirrhosis, aging…). The contribution of mitochondrial dysfunction to impairments in insulin metabolic signaling is also suggested by gene array analysis showing that reductions in gene expression, that regulates mitochondrial ATP production, are associated with insulin resistance and type 2 diabetes mellitus. Moreover, reductions in oxidative capa...

Sensors, Vol. 16, Pages 447: Concrete Condition Assessment Using Impact-Echo Method and Extreme Learning Machines

Fri, 25 Mar 2016 23:00:00 +0100

The impact-echo (IE) method is a popular non-destructive testing (NDT) technique widely used for measuring the thickness of plate-like structures and for detecting certain defects inside concrete elements or structures. However, the IE method is not effective for full condition assessment (i.e., defect detection, defect diagnosis, defect sizing and location), because the simple frequency spectrum analysis involved in the existing IE method is not sufficient to capture the IE signal patterns associated with different conditions. In this paper, we attempt to enhance the IE technique and enable it for full condition assessment of concrete elements by introducing advanced machine learning techniques for performing comprehensive analysis and pattern recognition of IE signals. Specifically, we u...

Sensors, Vol. 16, Pages 444: A Virtual Environment to Improve the Detection of Oral-Facial Malfunction in Children with Cerebral Palsy

Fri, 25 Mar 2016 23:00:00 +0100

The importance of an early rehabilitation process in children with cerebral palsy (CP) is widely recognized. On the one hand, new and useful treatment tools such as rehabilitation systems based on interactive technologies have appeared for rehabilitation of gross motor movements. On the other hand, from the therapeutic point of view, performing rehabilitation exercises with the facial muscles can improve the swallowing process, the facial expression through the management of muscles in the face, and even the speech of children with cerebral palsy. However, it is difficult to find interactive games to improve the detection and evaluation of oral-facial musculature dysfunctions in children with CP. This paper describes a framework based on strategies developed for interactive serious games t...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

Organic enrichment effects on a marine meiofauna community, with focus on Kinorhyncha

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: Available online 26 March 2016 Source:Zoologischer Anzeiger - A Journal of Comparative Zoology Author(s): Matteo Dal Zotto, Andrea Santulli, Roberto Simonini, M. Antonio Todaro Within the framework of a programme aimed at monitoring the impact of fish farming on the marine biota, we have had the opportunity to study the effect of the organic enrichment caused by the fish farm on meiofauna abundances and Kinorhyncha communities’ structure over two farming cycles. Up to now, studies on kinorhynchs have focussed mostly on the taxonomy, biogeography, and the ultrastructure, and, more recently, on the phylogenetic aspects of the taxon. Only few studies have dealt with the ecology of these creatures and studies focusing on the response of these animals to disturbances o...

An optimized second order stochastic learning algorithm for neural network training

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: 19 April 2016 Source:Neurocomputing, Volume 186 Author(s): Shan Sung Liew, Mohamed Khalil-Hani, Rabia Bakhteri This paper proposes an improved stochastic second order learning algorithm for supervised neural network training. The proposed algorithm, named bounded stochastic diagonal Levenberg–Marquardt (B-SDLM), utilizes both gradient and curvature information to achieve fast convergence while requiring only minimal computational overhead than the stochastic gradient descent (SGD) method. B-SDLM has only a single hyperparameter as opposed to most other learning algorithms that suffer from the hyperparameter overfitting problem due to having more hyperparameters to be tuned. Experiments using the multilayer perceptron (MLP) and convolutional neural network (CNN) mod...

Advances and trends in visual crowd analysis: A systematic survey and evaluation of crowd modelling techniques

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: 19 April 2016 Source:Neurocomputing, Volume 186 Author(s): M. Sami Zitouni, H. Bhaskar, J. Dias, M.E. Al-Mualla Visual recognition of crowd dynamics has had a huge impact on several applications including surveillance, situation awareness, homeland security and intelligent environments. However, the state-of-the-art in crowd analysis has become diverse due to factors such as: (a) the underlying definition of a crowd, (b) the constituent elements of the crowd processing model, (c) its application, hence (d) the dataset and (e) the evaluation criteria available for benchmarking. Although such diversity is healthy, the techniques for crowd modelling thus developed have failed to establish credibility therefore becoming unreliable and of questionable validity across dif...

Dynamic blind source separation based on source-direction prediction

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: 12 April 2016 Source:Neurocomputing, Volume 185 Author(s): Yangjie Wei, Yi Wang Deterministic techniques are based on the source-directions and multipath characteristics of the reverberant environment for different source signals. However, searching for the desired directions of the time-block sequence of an acoustic signal is time consuming, and existing deterministic methods rarely consider the motion properties of the acoustic source. In this paper, a dynamic source-direction prediction method for real-time blind convolutive mixtures based on a Kalman filter is proposed. First, the convolutive mixture signals captured by the coincident array geometry are formulated, and the relationship between source-direction and source separation is developed. Second, motion pre...

The sensori-motor model of the hippocampal place cells

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: 12 April 2016 Source:Neurocomputing, Volume 185 Author(s): Anu Aggarwal Hippocampal place cells are important in spatial navigation as their place specific firing provides a spatial map of the environment. Empirically, the place cell firing pattern seems to be determined by both the sensory and the motor inputs. However, the current models of the place cells assign either the sensory or the motor integration as the reason for their firing. In this paper, we propose an explanation for place cell firing based on integration of both sensory (vision, auditory, olfactory etc.) and motor inputs (through grid cells which process head direction cell and vestibular inputs). The inspiration for this model is the difference in visual information processing in animals with and wit...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

Intra-specific competitive co-evolutionary artificial neural network for data classification

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: 12 April 2016 Source:Neurocomputing, Volume 185 Author(s): Bee Yan Hiew, Shing Chiang Tan, Way Soong Lim This paper presents an alternative approach of competitive co-evolutionary (ComCoE) artificial neural network (ANN) developed for data classification. The motivation of this work is to employ an interactive game-based fitness evaluation method within a CoE framework to develop a compact and accurate ANN model. The proposed model uses only one population of radial basis function artificial neural networks (RBFANNs) in the CoE framework to find out an optimised RBFANN. In the ComCoE process, the RBFANNs compete in an intra-specific competition environment, which is driven by a game-based fitness evaluation method. The fitness evaluation for each RBFANN is made by co...

High levels of heavy metal accumulation in dental calculus of smokers: a pilot inductively coupled plasma mass spectrometry study

Fri, 25 Mar 2016 23:00:00 +0100

ConclusionWithin the limitations of this study, it can be concluded that the elementary composition of dental calculus may be affected by environmental factors such as tobacco smoke. Therefore, dental calculus may be utilized as a non‐invasive diagnostic biological material for monitoring chronic oral heavy metal exposition. However, further studies are required to evaluate its diagnostic potential. (Source: Journal of Periodontal Research)

A review of factors affecting electrostatic charging of pharmaceuticals and adhesive mixtures for inhalation

Fri, 25 Mar 2016 23:00:00 +0100

This article reviews the factors affecting the electrostatic charging of pharmaceutical powders with a focus on dry powder inhalations. The influences of particle resistivity, size distribution, shape distribution, surface roughness, polymorphic form and hygroscopicity, as well as the effects of moisture uptake, environmental conditions, pharmaceutical processing (i.e., milling, sieving, spray drying and blending), and storage on the electrostatic charge behaviours of pharmaceuticals, with focus on inhalation powders, were reviewed. The influence of electrostatic charge on the performance of dry powder inhaler formulations in terms of drug content homogeneity, the passage of drug through the inhaler device, drug–carrier adhesion/detachment, and drug deposition on the respiratory airways ...

The effects of the integration of external and internal communication features in digital magazines on consumers' magazine attitude

Fri, 25 Mar 2016 23:00:00 +0100

This study investigates the effects of external and internal communication features on consumers' digital magazine attitude, and the processes (i.e., perceived interactivity and social presence) underlying these effects. Both feature types enable communication between two or more people. Though, in the case of external communication features, the interactions take place outside the digital magazine (e.g., on Facebook), whereas in the case of internal communication features, the communication takes place inside the digital environment of the magazine. In a two-wave experiment with a 2 (external communication features: present/absent) × 2 (internal communication features: present/absent) between-subjects design, 192 participants were exposed to a digital tablet magazine in which the prese...

Exploring user satisfaction for e-learning systems via usage-based metrics and system usability scale analysis

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: August 2016 Source:Computers in Human Behavior, Volume 61 Author(s): Nouzha Harrati, Imed Bouchrika, Abdelkamel Tari, Ammar Ladjailia The use of e-learning technology is incontestably recognized as an important and integral part of the educational process. Considerable research studies are carried out in order to apprehend how effective and usable e-learning systems. In this paper, an empirical-based study is conducted to explore how lecturers interact with an e-learning environment based on a predefined task model describing low-level interactions. Client-side log data is collected from university lecturers from the Electrical and Computer Science departments. Subsequently, data analysis is conducted to infer the usability degree from the estimated usage metrics to...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

Social media users and their social adaptation process in virtual environment: Is it easier for Turkish Cypriots to be social but virtual beings?

Fri, 25 Mar 2016 23:00:00 +0100

This study examined the relationship and difference between offline life and virtual environment social adaptation among Turkish Cypriots. A total of 113 male and female Turkish Cypriot Facebook users were surveyed using the modified “Hacettepe Personality Inventory” to measure their social adaptation. The results revealed a negative relationship between offline life and virtual environment social adaptation and a statistically significant difference. No gender difference was found in offline and online social adaptation. There was a significant association between the type of pictures participants prefer to upload and their perceived others self-evaluation. (Source: Computers in Human Behavior)

Are Diagnostic Radiographers Image Acquisition Experts Within the General Radiographic Environment?

Fri, 25 Mar 2016 23:00:00 +0100

This article challenges whether diagnostic radiographers are image acquisition experts after the introduction of direct digital radiography (DDR). (Source: Journal of Medical Imaging and Radiation Sciences)

IJERPH, Vol. 13, Pages 374: Identification of Haplotype Tag Single-Nucleotide Polymorphisms within the PPAR Family Genes and Their Clinical Relevance in Patients with Major Trauma

Fri, 25 Mar 2016 23:00:00 +0100

Conclusions: The rs10865710 polymorphism in the PPARγ gene might be used to assess the risk of sepsis and multiple organ dysfunction syndrome (MODS) in trauma patients. (Source: International Journal of Environmental Research and Public Health)

IJERPH, Vol. 13, Pages 373: Pathway Analysis Revealed Potential Diverse Health Impacts of Flavonoids that Bind Estrogen Receptors

Fri, 25 Mar 2016 23:00:00 +0100

Flavonoids are frequently used as dietary supplements in the absence of research evidence regarding health benefits or toxicity. Furthermore, ingested doses could far exceed those received from diet in the course of normal living. Some flavonoids exhibit binding to estrogen receptors (ERs) with consequential vigilance by regulatory authorities at the U.S. EPA and FDA. Regulatory authorities must consider both beneficial claims and potential adverse effects, warranting the increases in research that has spanned almost two decades. Here, we report pathway enrichment of 14 targets from the Comparative Toxicogenomics Database (CTD) and the Herbal Ingredients’ Targets (HIT) database for 22 flavonoids that bind ERs. The selected flavonoids are confirmed ER binders from our earlier studies, and...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

Molecules, Vol. 21, Pages 414: Effect of Genotype and Environment on Salvia miltiorrhiza Roots Using LC/MS-Based Metabolomics

Fri, 25 Mar 2016 23:00:00 +0100

This study found that both the same S. miltiorrhiza genotype growing at three different locations and four S. miltiorrhiza genotypes growing at the same location had significant metabonomic differences identified by the principal component analysis (PCA) approach. By using orthogonal projection to latent structure with discriminant analysis (OPLS-DA), 16 and 14 secondary metabolites can be used as potential location-specific and genotype-specific markers in S. miltiorrhiza, respectively. The specificity of LC/MS profiles offered a powerful tool to discriminate S. miltiorrhiza samples according to genotypes or locations. (Source: Molecules)

Homology Modeling and Molecular Docking Studies of Drosophila and Aedes Sex Peptide Receptors

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: Available online 25 March 2016 Source:Journal of Molecular Graphics and Modelling Author(s): Jeong-hyun Kim, Soo-Kyung Kim, Jae-Hyuk Lee, Young-Joon Kim, William A. Goddard, Yong-Chul Kim The Drosophila melanogaster sex peptide receptor (DrmSPR), which is a G protein-coupled receptor (GPCR), is known as the specific receptor for sex peptide (SP). It is responsible for the reproductive behavior in the Drosophila model system; in particular, it is involved in the post-mating responses such as the increase in egg-laying ability and decrease in receptivity in females. In a previous study, we discovered a small molecule agonist of DrmSPR for the first time, which could not, however, activate Aedes aegypti SPR (AedesSPR). To investigate the binding mechanism of the smal...

Chloroquine inhibits Rhodococcus equi replication in murine and foal alveolar macrophages by iron-starvation

Fri, 25 Mar 2016 23:00:00 +0100

Publication date: Available online 26 March 2016 Source:Veterinary Microbiology Author(s): Leticia T. Gressler, Angela I. Bordin, Cole M. McQueen, Noah D. Cohen, Agueda Castagna de Vargas Rhodococcus equi preferentially infects macrophages causing pyogranulomatous pneumonia in young foals. Both the vapA and rhbC genes are up-regulated in an iron (Fe)-deprived environment, such as that found within macrophages. Chloroquine (CQ) is a drug widely used against malaria that suppresses the intracellular availability of Fe in eukaryotic cells. The main objective of this study was to evaluate the ability of CQ to inhibit replication of virulent R. equi within murine (J774A.1) and foal alveolar macrophages (AMs) and to verify whether the mechanism of inhibition could be Fe-deprivation-depend...

Trajectories of quality of life in patients with traumatic limb injury: a 2-year follow-up study

Fri, 25 Mar 2016 23:00:00 +0100

Conclusions This study found that the trajectories in the 4 QOL domains were cubic trajectories in patients with TLI. These findings indicate that clinicians should pay additional attention to improve the patients’ QOL in the first 6 months after injury and to prevent or reduce QOL deterioration at 6–12 months. (Source: Quality of Life Research)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

This Woman Fit 3 Years Of Her Trash In A Freaking Mason Jar

Fri, 25 Mar 2016 22:16:34 +0100

Sustainability never looked so stylish -- or straightforward. Lauren Singer runs Trash Is for Tossers, a no-waste lifestyle blog that is brimming with smart, simple and sleek-looking tips, tricks and DIY projects for adopting a more sustainable life. "I would like people to take away that we can all, regardless of our background, our beliefs, where we live or our socioeconomic status, take simple steps to reduce our environmental impact. It is simple to say no to a plastic straw or carry a reusable bag," Singer told The Huffington Post. Singer’s environmental epiphany struck her three years ago when she was a senior at NYU, where she was earning a degree in environment studies. “One day after class I went home to make dinner and opened my refrigerator and saw that everything i...

On Prevention: Why Yoga Is Good for Mental Health

Fri, 25 Mar 2016 21:34:09 +0100

"I am strong, I am bold... my own power, I can hold." -- Bent on Learning Student Mantra In keeping with our series inspired by the Kennedy Forum's Mental Health State of the Union, this week we focus on prevention. Recently, we attended a gala to benefit Bent on Learning, a nonprofit that brings yoga classes to thousands of New York City public school students each week. Organizations like Bent on Learning are at the forefront of prevention, equipping students with skills that help them maintain good holistic health. Being a young person these days can be tough -- from navigating the academic pressures to succeed in a competitive environment to managing healthy social relationships both online and off -- growing up can be full of stressors, especially when you're a student in a large ...

Abiotic Protein Fragmentation by Manganese Oxide: Implications for a Mechanism to Supply Soil Biota with Oligopeptides

Fri, 25 Mar 2016 20:15:10 +0100

Environmental Science & TechnologyDOI: 10.1021/acs.est.5b04622 (Source: Environmental Science and Technology)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

Oxidative Dissolution of Silver Nanoparticles by Chlorine: Implications to Silver Nanoparticle Fate and Toxicity

Fri, 25 Mar 2016 20:14:35 +0100

Environmental Science & TechnologyDOI: 10.1021/acs.est.6b00037 (Source: Environmental Science and Technology)

The Icy Fire Beneath Norway's Seabed

Fri, 25 Mar 2016 20:09:38 +0100

This article originally appeared on Arctic Deeply. For weekly updates about Arctic geopolitics, economy, and ecology, you can sign up to the Arctic Deeply email list. -- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website. (Source: Science - The Huffington Post)

Thermal Reactor Model for Large-Scale Algae Cultivation in Vertical Flat Panel Photobioreactors

Fri, 25 Mar 2016 20:07:51 +0100

Environmental Science & TechnologyDOI: 10.1021/acs.est.5b05414 (Source: Environmental Science and Technology)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

Response to Comment on “Damages and expected deaths due to excess NOx emissions from 2009–2015 Volkswagen diesel vehicles”

Fri, 25 Mar 2016 20:07:28 +0100

Environmental Science & TechnologyDOI: 10.1021/acs.est.6b01157 (Source: Environmental Science and Technology)

Comment on “Damages and Expected Deaths Due to Excess NOx Emissions from 2009 to 2015 Volkswagen Diesel Vehicles”

Fri, 25 Mar 2016 20:06:28 +0100

Environmental Science & TechnologyDOI: 10.1021/acs.est.6b00856 (Source: Environmental Science and Technology)

Health system makes cutting-edge telemedicine affordable

Fri, 25 Mar 2016 20:04:00 +0100

With the right kind of equipment, can a video conference between an ambulance and an on-call neurologist deliver the same stroke assessment results as at the bedside in the emergency room? The University of Virginia Health System, after over one year of research, is poised to find out. Previously, AMA Wire® brought you the theory behind the University of Virginia (UVA) Health System’s research efforts to bring telemedicine to the ambulance so they can improve care for patients who are experiencing a stroke. We recently caught up with the UVA team to find out that their telestroke model iTreat is now in action. Andrew M. Southerland, MD, a neurologist with UVA, and his team already have provided this advanced telemedicine service to patients. “We have enrolled seven patients thus f...

To the Harvard 19: Do Better

Fri, 25 Mar 2016 19:56:52 +0100

To: Elizabeth Bartholet, Scott Brewer, Charles Donahue, Jr., Nancy Gertner, Janet Halley, Bruce L. Hay, Philip B. Heymann, David W. Kennedy, Duncan M. Kennedy, Randall L. Kennedy, Charles J. Ogletree, Jr., Richard D. Parker, J. Mark Ramseyer, David Rosenberg, Lewis D. Sargentich, David L. Shapiro, Henry J. Steiner, Jeannie C. Suk, Laurence H. Tribe There was no mutuality that night. The sense of entitlement to grope, mount, fondle, even penetrate  --  to any extent  --  any female body within reach that has a pulse, is not something that anyone should accept as reasonable, non-abusive, excusable behavior, even for a drunk guy. When this sense of entitlement is demonstrated, admittedly acted upon, and defended as such, it is clear that the person responsible, as well as the communit...

Sulfur Isotopic Fractionation of Carbonyl Sulfide during Degradation by Soil Bacteria

Fri, 25 Mar 2016 19:22:51 +0100

Environmental Science & TechnologyDOI: 10.1021/acs.est.5b05325 (Source: Environmental Science and Technology)

If Everyone Were Vegetarian, This Is How The World Would Look

Fri, 25 Mar 2016 19:16:33 +0100

Vegan butcher shops exist in the U.S. now, but only about three percent of the American population is fully vegetarian.  Imagine, for a moment, if steak houses became seitan houses and not a single person on the planet consumed meat. How would the world look? Very different, as the AsapScience video above explains. Without meat-eaters, the planet would have a lot more land available that could be restored from dry pastures into grasslands or forests. This could help counteract the intense climate change we're seeing today. In fact, many scientists believe consuming less meat could make a big impact on climate: Livestock production is responsible for about 15 percent of global greenhouse emissions, which contribute to global warming. Despite what we know about the environment...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

Effects of Lampricide on Olfaction and Behavior in Young-of-the-Year Lake Sturgeon (Acipenser fulvescens)

Fri, 25 Mar 2016 19:12:36 +0100

Environmental Science & TechnologyDOI: 10.1021/acs.est.6b01051 (Source: Environmental Science and Technology)

NGO Pledges $500 Million Towards Sustainable Development Goals

Fri, 25 Mar 2016 17:10:50 +0100

On the right Bruce Wilkinson, President and CEO of CMMB - Healthier Lives Worldwide. Next to him (in the middle) stands Ambassador Mwaba Kasese-Bota, Permanent Representative of the Mission of Zambia to the United Nations, at the CMMB conference on $500 million for the U.N. SDGs, event on March 21. Photo: CMMBBy Valentina IeriUNITED NATIONS, Mar 25 2016 (IPS)The Catholic Medical Mission Board (CMMB) – a leading international nonprofit health non-governmental organisation (NGO) – has pledged 500 million dollars to help implement the UN’s Sustainable Development Goals (SDGs)– with a specific focus on maternal, newborn, child and adolescent health. The money will be deployed through the NGO’s flagship initiatives CHAMPS – which is a maternal and child health progra...

Continuing education—“The action level”®

Fri, 25 Mar 2016 16:25:02 +0100

(Source: Journal of Occupational and Environmental Hygiene)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.


Fri, 25 Mar 2016 16:25:02 +0100

(Source: Journal of Occupational and Environmental Hygiene)

A method for evaluating aerosol leakage through the interface between protective suits and full-face respirators

Fri, 25 Mar 2016 16:25:02 +0100

(Source: Journal of Occupational and Environmental Hygiene)

Long duration measurements of whole-body vibration exposures associated with surface coal mining equipment compared to previous short-duration measurements

Fri, 25 Mar 2016 16:25:02 +0100

(Source: Journal of Occupational and Environmental Hygiene)

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.