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ASN Kidney Week 2016 abstract book link (PDF, 50 mB file)

Mon, 31 Oct 2016 20:44:39 GMT

Here is the link to the 2016 Kidney Week abstracts



FDA warns about hepatitis B reactivation with direct acting hepatitis C antivirals.

Wed, 05 Oct 2016 17:18:08 GMT

Patients who have already been infected by the HB virus and those who have ongoing infection are likely to develop serious liver conditions or even death when treated with HC direct-acting antiviral drugs for HC infection. The FDA has mandated the inclusion of "Boxed Warning," a prominent warning concerning the risks of HB virus reactivation on the HC direct-acting antiviral drug labels.



HDCN key zone access password problem fixed.

Thu, 01 Sep 2016 15:07:50 GMT

Key zone access to HDCN has been fixed. Apologies to all for the server error message, which is due to a programming error made several days ago.



Good Staph. in the nose makes novel peptide antibiotic that kills bad Staph.

Thu, 28 Jul 2016 23:16:32 GMT

FoxNews (Reuters): Scientists in Germany have discovered a bacteria hiding out in peoples' noses that produces an antibiotic compound that can kill several dangerous pathogens, including the superbug MRSA.



Hemodialysis University Chicago, Sept. 9-10 (up to 12 CME/CEUs)

Sun, 24 Jul 2016 03:01:30 GMT

ISHD: Come to Chicago to experience a top tier educational activity hosted by the International Society for Hemodialysis, held in late summer / early fall, when Chicago is at its most beautiful (September 9th and 10th, 2016). The program is designed to foster discussion and questions and answers to practical problems faced in the dialysis unit.



Cyanobacteria becoming a widespread problem in U.S. lakes

Sat, 23 Jul 2016 15:32:41 GMT

Daily Mail: Meanwhile, all activities at Utah Lake have been canceled indefinitely after it was revealed the toxic algal bloom covering the water was becoming more hazardous. Cyanobacteria cells release higher levels of toxins into the water as they die - making the water more lethal even as the number of cells drop in the lake, which lies in Utah Valley. More than 100 people exposed to the bloom called the Utah Poison Control Center last Friday, reporting symptoms of vomiting, diarrhea, fever, skin and eye irritation and rashes. Although no definitive link has yet been made with the symptoms and the bloom, officials said they were consistent with cyanotoxin exposure. Read more: http://www.dailymail.co.uk/news/article-3704157/Mysterious-green-foam-bubbling-Utah-storm-drain.html#ixzz4FFKmMwLr Follow us: @MailOnline on Twitter | DailyMail on Facebook



Dr. Fred Coe vides on urine calcium supersaturation in stone disease.

Tue, 12 Jul 2016 15:53:58 GMT

Univ. of Chicago: This is a three part video about supersaturation, the most unique and critical measurement for evaluation and prevention of kidney stones. Specifically it is about the calcium crystal supersaturations, calcium oxalate and calcium phosphates. The main theme is how supersaturation can be produced and maintained.



FDA issues warning about Shiga-toxin producing E. Coli found in flour

Thu, 30 Jun 2016 16:19:09 GMT

Atlanta Journal Constitution: What’s the risk in dough? (Hint: It’s not the egg). The FDA says the risk comes not from the ingredient many would think – raw eggs – but instead from batches of flour contaminated with the E. coli bacteria Dozens have been sickened by the Shiga toxin-producing E. coli O121 after they ate raw flour. The flour was processed at a General Mills plant in Kansas City, Mo. General Mills has voluntarily recalled 10 million pounds of flour sold under the Gold Medal, Gold Medal Wondra and Signature Kitchen labels.



The Brigham Renal Board Review Course: August 8-12, 2016 in Boston

Wed, 01 Jun 2016 17:02:47 GMT

Brigham: Important Message from the Course Directors: We are extremely delighted to invite you to participate in the 2016 Brigham Renal Board Review Course at the Fairmont Copley Plaza Hotel in Boston. This year's Brigham Renal Board Review Course will focus on a systematic case-based approach in keeping with the style of the ABIM renal board examination. All lecturers will lead off with board-style question(s) to set the tone for the thought process, provide background key data & mechanisms, and provide you with case-based presentations to support diagnostic and therapeutic approaches. A special session on "How to Pass the Boards" will also be offered. Register today! Sincerely, ..... Joseph V. Bonventre, MD, PhD ....... Jamil R. Azzi, MD .......... Anil Chandraker, MD ........ Gearoid M. McMahon, MB BCh ......... Course Directors



Three days of fasting every 10 days improve autoimmune diseases (in mice).

Sun, 29 May 2016 15:22:00 GMT

EurekAlert: For the first part of the study, researchers put a group of mice with autoimmune disease on a fasting-mimicking diet for three days, every seven days for three cycles, with a control group on a standard diet for comparison. Results showed that the fasting-mimicking diet reduced disease symptoms in all the mice, and "caused complete recovery for 20 percent of the animals," the researchers wrote.



Nicotinamide riboside protects mice from effects of diabetes.

Sun, 29 May 2016 15:19:03 GMT

EurekAlert: A naturally occurring vitamin, nicotinamide riboside (NR), can lower blood sugar levels, reduce fatty liver, and prevent peripheral nerve damage in mouse models of prediabetes and type 2 diabetes (T2D), according to a new study by researchers at the University of Iowa and the Iowa City VA Health Care System.



Smoking increases risk of CKD progression in African Americans

Sun, 29 May 2016 15:17:18 GMT

EurekAlert: After adjustment for factors such as age, gender, physical activity, diabetes, hypertension and prevalent cardiovascular disease, researchers found that: the decline in kidney function was 83 percent higher overall in current smokers compared to those who had never smoked; the rate of kidney decline worsened with more smoking: those who smoked up to 19 cigarettes daily had 75 percent greater decline in kidney function; while those who smoked 20 or more cigarettes a day had a 97 percent greater decline in kidney function.



CRIC study shows a high urinary sodium excretion in CKD linked to higher CV risk.

Tue, 24 May 2016 18:15:37 GMT

JAMA: Conclusions and Relevance Among patients with CKD, higher urinary sodium excretion was associated with increased risk of CVD.



SPRINT shows lower than 120 BP systolic target in elderly results in improved outcomes

Fri, 20 May 2016 18:02:53 GMT

JAMA: Conclusions and Relevance Among ambulatory adults aged 75 years or older, treating to an SBP target of less than 120 mm Hg compared with an SBP target of less than 140 mm Hg resulted in significantly lower rates of fatal and nonfatal major cardiovascular events and death from any cause.



Tetraspanin-7 as an antibody target for type 1 diabete

Wed, 27 Apr 2016 05:52:30 GMT

Capitalberg.com: Finally understanding exactly how the disease works, the team of scientists from the UK and Italy discovered the fifth molecule affected by the condition – tetraspanin-7. Not only will the fact that the scientists know all five molecules affect detection methods for the condition, but it might also help in developing a proper treatment other than constant insulin injections.



New bacteria called Elizabethkingia affecting Midwest patients.

Thu, 14 Apr 2016 01:51:53 GMT

CBS: A bacterial infection called Elizabethkingia has already claimed at least 20 lives in Wisconsin and Michigan. Now, the first case has been confirmed in Illinois and has taken another life, reports CBS Chicago.



AC6 gene therapy improves cardiac function in patients with heart failure.

Wed, 30 Mar 2016 20:11:40 GMT

UPI: Patients seemed to stay healthier after the treatment, too. According to the researchers, while 29 percent of those on a placebo ended up admitted to the hospital for heart failure over the year of follow-up, only 9.5 percent of those who got the gene transfer therapy did so.



Oops! Vegetarian diet may have some drawbacks.

Wed, 30 Mar 2016 19:20:12 GMT

Telegraph (Sarah Knapton): Long term vegetarianism can lead to genetic mutations which raise the risk of heart disease and cancer, scientists have found. Populations who have had a primarily vegetarian diet for generations were found to be far more likely to carry DNA which makes them susceptible to inflammation. Scientists in the US believe that the mutation occured to make it easier for vegetarians to absorb essential fatty acids from plants.



Updated CKD booklet for professionals released

Thu, 17 Mar 2016 16:45:45 GMT

Dr. Jerry Yee has released the 7th edition of his CKD Booklet for professionals. The booklet can be downloaded in .pdf format via the following link: http://ghsrenal.com/ckd/HFHS_CKD_GUIDELINES_V7.0.pdf



NEJM article re desensitization to HLA-incompatible live donors.

Thu, 10 Mar 2016 03:33:28 GMT

NEJM: Conclusions. This multicenter study validated single-center evidence that patients who received kidney transplants from HLA-incompatible live donors had a substantial survival benefit as compared with patients who did not undergo transplantation and those who waited for transplants from deceased donors.



Desensitization procedure allows kidney transplants from any (living) donor.

Thu, 10 Mar 2016 03:31:04 GMT

NY Times: In the new study, published Wednesday in The New England Journal of Medicine, doctors successfully altered patients’ immune systems to allow them to accept kidneys from incompatible donors. Significantly more of those patients were still alive after eight years than patients who had remained on waiting lists or received a kidney transplanted from a deceased donor.



ISHD publishes practical manual for implementing home hemodialysis

Wed, 09 Mar 2016 19:44:56 GMT

ISHD: The manual is designed to help caregivers set-up or expand a program of delivering hemodialysis in the home, and also contains useful information for patients who want to pursue this option. It is now available via amazon.com and on-line at the ishd.org website.



Is the FDA allowing promotion of off-label uses of drugs as free speech?

Wed, 09 Mar 2016 19:42:23 GMT

UPI: The U.S. Food and Drug Administration agreed to allow a pharmaceutical company to promote off-label uses not approved by the agency for one of its drugs, based on its right to free speech, according to the company.



Phage Therapy 2016 World Congress meets this June in Paris.

Mon, 29 Feb 2016 20:50:25 GMT

TID: On behalf of Taskforce for Infectious Diseases Committee, it is our pleasure to announce the 4th World Congress on Targeting Infectious Diseases dedicated to Phage Therapy. This international conference is scheduled in Paris, next June 2-3, 2016.



When will be see phage therapy for exit site and access infections?

Mon, 29 Feb 2016 20:44:28 GMT

Yahoo News: Within hours, he was on a plane to Tblisi. "Without it, I wouldn't be here," Novou told AFP on the sidelines of a conference in Paris about the mostly forgotten therapy, which remains marginal outside a few former Soviet bloc countries.



Treatment of BP below 140 systolic in persons with diabetes may be counterproductive.

Sat, 27 Feb 2016 16:30:36 GMT

MedPageToday: In diabetic patients with systolic blood pressure (SBP) less than 140 mm Hg at baseline, additional antihypertensive treatment increased the risk of cardiovascular mortality by 15%, reported co-authors Mattias Brunstroem a doctoral student, and Bo Carlberg, MD, of Umea niversity in Sweden.