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Last Build Date: Thu, 23 Oct 2014 23:35:53 GMT

Copyright: Copyright 2018,

Renal Disease and Electrolyte Course, Aspen, CO; July 23-27, 2018

Thu, 15 Mar 2018 15:08:59 GMT

University of Colorado: Registration: To register visit or contact Pam Welker at (303)724-3551 or at

USRDS Annual Report 2017

Mon, 12 Mar 2018 16:00:23 GMT

USRDS: US Renal Data System 2017 Annual Data Report: Epidemiology of Kidney Disease in the United States

In ICU, Ringer's lactate also better than saline.

Thu, 01 Mar 2018 05:12:32 GMT

NEJM: Conclusions: Among critically ill adults, the use of balanced crystalloids for intravenous fluid administration resulted in a lower rate of the composite outcome of death from any cause, new renal-replacement therapy, or persistent renal dysfunction than the use of saline.

Ringer's lactate causes less kidney injury than saline.

Thu, 01 Mar 2018 05:10:13 GMT

NEJM: Balanced crystalloids resulted in a lower incidence of major adverse kidney events within 30 days than saline (4.7% vs. 5.6%; adjusted odds ratio, 0.82; 95% CI, 0.70 to 0.95; P=0.01).

Lp(a) in the news in the New York Times

Fri, 12 Jan 2018 05:26:08 GMT

NY Times (Anahad O'Connor): “Only a small percentage of physicians know about this,” she said. “The biggest challenge for patients is finding knowledgeable physicians who know about this and can help them.”

Inhibitors of NMMT reduce obesity by increasing fat cell metabolism.

Tue, 09 Jan 2018 20:55:32 GMT

Biochem Pharmacol (Neelakantan et al): Research scientists at the University of Texas Medical Branch (UTMB) at Galveston say they developed a promising new drug that curbs obesity without dieting and, based upon preliminary study findings, they may be on their way to unleashing a breakthrough for the millions who struggle with their weight. "Treatment of diet-induced obese mice systemically with a potent NNMT inhibitor significantly reduced body weight and white adipose mass, decreased adipocyte size, and lowered plasma total cholesterol levels. Notably, administration of NNMT inhibitors did not impact total food intake nor produce any observable adverse effects."

J-curve in BP studies is an artifact - similar to dose targeting bias in HEMO.

Thu, 04 Jan 2018 23:09:41 GMT

Circulation (Kalkman et al): Conclusions: Low on-treatment SBP levels are associated with increased cardiovascular events and all-cause mortality. This association is independent of the attained blood pressure level because the J curve aligns with the SBP target. Our results suggest that the benefit or risk associated with intensive blood pressure–lowering treatment can be established only via randomized clinical trials.

Toxic algae now a nationwide threat.

Fri, 17 Nov 2017 02:22:54 GMT

AP: MONROE, Mich. (AP) — Competing in a bass fishing tournament two years ago, Todd Steele cast his rod from his 21-foot motorboat — unaware that he was being poisoned. A thick, green scum coated western Lake Erie. And Steele, a semipro angler, was sickened by it.

HDCN server move still in progress

Mon, 13 Nov 2017 23:16:04 GMT

We are still in the process of moving our sever. The CME and CEU certificates don't yet work, so please hold off in taking any tests on the site. The old audio files from ASN and other meetings should work now. Suggest you use VLC player to access them -- even the old Windows Media player files as well as the Real Media files open well using this player. Get the VLC player at

HDCN moving its registration and CME server

Wed, 08 Nov 2017 03:43:33 GMT

We are in the process of moving our registration and CME server, and all emails related to this server. There may be problems for the next few days until this server move is finished.

Hypervirulent, carbipenem-resistant Klebsiella pneumonia outbreak in China.

Wed, 06 Sep 2017 02:38:59 GMT

Ibankcoin: Scientists in Hangzhou, China have discovered a new strain of antibiotic-resistant pneumonia which spreads incredibly fast, after a 2016 outbreak in a hospital ICU led to the deaths of five patients ranging in age from 53 to 73. In findings published in The Lancet, researchers conclude that the new superbug poses a “substantial threat to human health” due to the fact that it is “simultaneously hypervirulent, multidrug resistant, and highly transmissible.”

ISHD Hemodialysis University, Chicago, IL Sept. 7-9, 2017; with CVC insertion precourse

Fri, 18 Aug 2017 20:55:19 GMT

ISHD: Come to the ISHD 2-day Hemodialysis University, to be held in Chicago at the Oak Lawn Hilton (4 miles south of Midway Airport), Sept. 7-9th. On Thursday, September 7th, registration permitting, we will hold a precourse focusing on CVC catheter insertion. For program and registration form click on the hyperlink, or go to

NEJM: Idarucizumab effective for reversal of dabigatran effects.

Sat, 12 Aug 2017 04:17:08 GMT

NEJM: Conclusions. In emergency situations, idarucizumab rapidly, durably, and safely reversed the anticoagulant effect of dabigatran.

Immunotherapy may arrest damage of beta cells in type 1 diabetes.

Fri, 11 Aug 2017 00:59:32 GMT

LA Times: After a quarter-century of failed efforts to treat diabetes with an immune therapy, the experimental treatment appeared to quell the immune system’s assaults on the body’s insulin-production machinery. The authors of the new study call their experimental treatment “an appealing strategy for prevention,” both in the earliest stages of Type-1 diabetes and in children who are at high genetic risk of developing the disease.

Fresenius inks deal to acquire NxStage.

Fri, 11 Aug 2017 00:56:29 GMT

Medical Device Online: Fresenius Medical Care intends to acquire all outstanding shares of NxStage through a merger for USD 30.00 per common share, thus the transaction would be valued at approximately USD 2.0 billion. The merger, which has been approved by NxStage’s board, is subject to approval of NxStage stockholders, receipt of regulatory approvals and other customary closing conditions. Fresenius Medical Care currently expects the closing to occur in 2018.

Gene-editing of pigs increases suitability of their organs for transplant into humans.

Fri, 11 Aug 2017 00:53:54 GMT

Telegraph (Sarah Knapton): Pig organs could soon be transplanted into patients after Harvard University genetically removed a virus inherent in the animal’s DNA which makes it incompatible with humans.

Can LIF be used to cure autoimmune diseases such as multiple sclerosis? and more?

Tue, 13 Jun 2017 05:28:23 GMT

Cambridge News: Dr. Su Metcalfe of LIFNano: "We’re not using any drugs, we’re simply switching on the body’s own systems of self-tolerance and repair. There aren’t any side effects because all we’re doing is tipping the balance. Auto-immunity happens when that balance has gone awry slightly, and we simply reset that. Once you’ve done that, it becomes self-sustaining and you don’t have to keep giving therapy, because the body has its balance back."

Dr. Fred Coe's Kidney Stone Guide Book - a work in progress.

Tue, 06 Jun 2017 16:13:42 GMT

Dr. Coe: "As a way to fulfil that idea I have made and remade this book through many forms by now. Some of you have, perhaps, encountered earlier versions appearing and disappearing like ghosts. Gradually, I settled on the idea of a guide book. Here and there, in the past, I have written like a guide. My walking tours of supersaturation, for example. But this is more ambitious. I am after synthesis and cohesion because I believe they will make it easier for patients to follow the story and achieve stone prevention"

Late-breaking clinical trials at the ERA-EDTA

Sun, 04 Jun 2017 14:24:22 GMT

ERA-EDTA: NEFIGAN Trial... Novel targeted-release formulation of budesonide reduced proteinuria in IGAN patients ........................................... New insights from the COSMOS study... 12% mortality reduction, if serum phosphate levels are brought into the target range of 3.6 to 5.2 mg/dL. .................................................. Whom to treat – and not to treat – with immunosuppressive drugs?... High serum levels of Gd-IgA1 predict poor renal outcomes in IgAN ................................... Results of the EXCITE trial... A home-based exercise program significantly improves physical performance in dialysis patients ..................................... Active Vitamin D does not prevent cardiovascular disease J-DAVID Trial shows no benefit ................................ AURA-LV trial shows promising results!... Complete remission of lupus nephritis is three times more likely with voclosporin

Novel wireless device accurately measures walking speed.

Tue, 02 May 2017 22:28:34 GMT

Yahoo News: New York, May 2 (IANS) Researchers at Massachusetts Institute of Technology (MIT) have developed a device that can measure the walking speed of people with 95 to 99 per cent accuracy using wireless signals, without requiring that the person wear or carry a sensor. A growing body of research suggests that how fast one walks could tell a lot about health issues like cognitive decline, falls, and even certain cardiac or pulmonary diseases.

High salt diet makes subjects drink less and eat more !?

Tue, 18 Apr 2017 18:46:19 GMT

News Talk 770: Consuming salt does not make you thirsty – but it does make you hungry, a new study suggests. Eating salt is known to stimulate the production of urine, a fact that had many in the scientific community believe that salt makes one thirstier. However, it’s a myth that has now been busted in a Mars spaceflight simulation study led by researchers at the Vanderbilt University Medical Center in the U.S. and the Max-Delbrueck Center for Molecular Medicine in Germany. To find this out, scientists kept 10 healthy men within sealed living quarters and fed them a controlled high-salt diet for 205 days.

Device extracts water from air with relative humidity as low as 20%

Sat, 15 Apr 2017 15:33:42 GMT

NY Post (article published in Science): Engineers at MIT and the University of California Berkeley have designed a system, powered by sunlight, that can turn air into liters of drinkable water. This box has the potential to help drought-stricken communities, desert explorers or — someday — astronauts traveling to dry, dusty planets. The report was published April 13 in Science.

Graphene sieve membrane turns seawater drinkable.

Tue, 04 Apr 2017 15:15:53 GMT

Yahoo, Nature Nanotechnology: A study published in the journal Nature Nanotechnology describes how the filtration system works by precisely controling the membrane’s pore size to sieve common salts out of salty water. “Realization of scalable membranes with uniform pore size down to atomic scale is a significant step forward and will open new possibilities for improving the efficiency of desalination technology,” said Professor Rahul Nair.

Lungs play a role in making platelets in mice.

Thu, 23 Mar 2017 16:32:14 GMT

Fox News (reporting on study in Nature): Scientists studying the lungs of mice discovered to their surprise that the lungs produced about half the platelets, blood components necessary for stanching, in the creatures' circulation, according to a release.

Smartphones to become pocket doctors.

Wed, 22 Feb 2017 07:47:42 GMT

Telegraph: Professor Shwetak Patel, of the University of Washington is currently devising an app which can detect red blood cell levels simply by placing a finger over the camera and flash, so that a bright beam of light shines through the skin. Such a blood screening tool could quickly spot anaemia.

Pharmacies miss some drug interactions that are known to cause serious issues.

Wed, 28 Dec 2016 13:50:40 GMT

Chicago Tribune: The Tribune reporter walked into an Evanston CVS pharmacy carrying two prescriptions: one for a common antibiotic, the other for a popular anti-cholesterol drug. Taken alone, these two drugs, clarithromycin and simvastatin, are relatively safe. But taken together they can cause a severe breakdown in muscle tissue and lead to kidney failure and death...