Last Build Date: Tue, 29 Mar 2016 07:48:16 +0100
Mon, 28 Mar 2016 15:30:54 +0100Experts at Ramsay Health Care UK advise when stools are healthy - and when to visit a doctor. Bowel cancer is the third most common cancer, with 1.4 million new cases diagnosed each year. (Source: the Mail online | Health)
Sun, 27 Mar 2016 00:01:00 +0100LOSING her mother to bowel cancer has made ITV news presenter Charlene White more determined to help other sufferers. (Source: Daily Express - Health)
Thu, 10 Mar 2016 00:00:00 +0100Authors: Swash C Abstract In the UK, 62% of the population are now described as being either overweight or obese. People with weight-management issues are more likely to suffer from cardiovascular disease and diabetes, as well as having an increased risk of cancer, including bowel cancer. Following the initial National Institute for Health and Care Excellence guidance in 2006, revised in 2014, health professionals have a more proactive role in identifying people with weight-management issues and supporting them to achieve a weight that helps reduce their health risks. This includes referrals to bariatric surgeons for consideration for surgery if appropriate. One particular surgical procedure, the Roux-en-Y, is not reversible and alters the capacity of the stomach and function of th...
Sat, 05 Mar 2016 15:32:02 +0100CONCLUSION: Within 10 years of the introduction of screening colonoscopy in Germany, the incidence of bowel cancer in persons over age 55 fell by 17-26%, after having risen steadily over the preceding decades. PMID: 26940777 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Fri, 04 Mar 2016 17:42:00 +0100Long-term aspirin use is linked to lower risk for developing gastrointestinal tract cancers, according to US researchers. (Source: Nursing Times)
Fri, 04 Mar 2016 10:30:00 +0100ConclusionThis study has made use of long-term follow-up data from two large US studies to examine the link between regular aspirin use and risk of cancer. The research did find that regular use of aspirin was associated with a very small reduction in the overall risk of cancer. When looking by cancer type, the only cancer with a clear risk reduction from aspirin use seems to be bowel cancer. There were no significant links for any other cancer type (the definitions of a reduced risk for "gastrointestinal tract cancers" but no link for "other gastrointestinal tract cancers" seem rather unclear). The risk reduction for bowel cancer seems to start from taking 0.5 to 1.5 standard-dose tablets (325mg) per week, which is roughly equivalent to a daily low-dose aspirin. It s...
Thu, 03 Mar 2016 18:10:43 +0100People at risk of stomach and bowel cancer should consider taking aspirin if their doctor agrees, say health experts (Source: Telegraph Health)
Mon, 29 Feb 2016 23:00:00 +0100ConclusionOverall, two thirds of ileostomies were reversed within 18 months. Reversal rates were linked to patient and cancer characteristics (age, sex, fitness, and stage), mode of surgical access, and socioeconomic deprivation. Observed lower reversal rates in patients from poorer backgrounds may indicate inequity in access.This article is protected by copyright. All rights reserved. (Source: Colorectal Disease)
Sat, 27 Feb 2016 22:00:00 +0100Now free of stage four bowel cancer, the BBC newsreader says he wouldn't change anything about the previous year of his life (Source: Telegraph Health)
Fri, 26 Feb 2016 12:44:02 +0100Authors: Hingston G PMID: 26913916 [PubMed - as supplied by publisher] (Source: New Zealand Medical Journal)
Fri, 26 Feb 2016 00:00:00 +0100(Source: Asia-Pacific Journal of Clinical Oncology)
Mon, 22 Feb 2016 00:00:00 +0100ConclusionsPatients with NBCSP‐detected CRC have a markedly reduced risk of CRC recurrence and death compared with patients with a symptomatic presentation. The dominant driver of this appears to be earlier stage at diagnosis. Increased promotion of the impact of the NBCSP, including data related to the survival impact, should be undertaken to increase participation rates and achieve further survival gains. (Source: Internal Medicine Journal)
Thu, 18 Feb 2016 02:49:02 +0100Conclusion A pre-post design was considered more appropriate than a randomized control trial due to an inability to match pharmacies. Limitations of this study were: lack of control over adherence to the study protocol by pharmacy staff; no direct measure of client feedback on the JLT; and loss to follow-up. The JLT was effective in prompting decision-making by pharmacy staff and inter-professional care between pharmacies and general practice, in triage of clients at risk of bowel cancer. PMID: 26700973 [PubMed - as supplied by publisher] (Source: Current Medical Research and Opinion)
Wed, 17 Feb 2016 00:00:00 +0100Authors: Abstract Essential facts Colorectal cancer is the fourth most common cancer in the UK, after breast, lung and prostate cancer, with around 41,600 people in the UK diagnosed each year. It is the second most common cause of cancer death in the UK. According to the charity Bowel Cancer UK, 98% of people diagnosed at the earliest stage will survive, while less than 10% of those diagnosed at the latest stage will survive more than five years. PMID: 26884013 [PubMed - in process] (Source: Nursing Standard)
Sat, 13 Feb 2016 18:45:14 +0100You may have heard of Dry January, a campaign run in the U.K. by Alcohol Concern. To promote alcohol awareness, it involves (as you’ve likely gathered) completely abstaining from alcohol for the month of January. It’s a valuable campaign with noble intentions, but a minority of participants may unfortunately miss the wider point. A month of strict abstinence does lead some to drink more than they should come February 1. Remaining alcohol free for a month is an achievement which deserves to be rewarded, but compensatory drinking is not what Dry January is trying to advocate. A healthy attitude towards consumption (not necessarily total abstinence) is needed during every month of the year to reap lasting health benefits. Alcohol and Health The National Council on Alcoholism and Drug De...
Thu, 11 Feb 2016 13:52:02 +0100Researchers have discovered how cells in the human body build their own ‘railway networks’, throwing light on how diseases such as bowel cancer work. The microtubule tracks are vital for functions such as cell division and are a key target for key cancer drugs. Now researchers are studying how these microtubule tracks are assembled. (Source: ScienceDaily Headlines)
Thu, 11 Feb 2016 05:00:00 +0100(Cancer Research UK) A new test could help patients with advanced bowel cancer get the best treatment for their disease, according to a Cancer Research UK clinical trial published today in JAMA Oncology. (Source: EurekAlert! - Cancer)
Wed, 10 Feb 2016 12:31:01 +0100Conclusions: The present study highlights specific knowledge gaps and confusion with regard to bowel cancer and screening. Addressing these gaps through the provision of clear, coordinated information may shift attitudes to screening and increase participation.So what?: Given the Australian Government's recent commitment to expand the National Bowel Cancer Screening Program, insight into what is driving current perceptions, attitudes and subsequent participation in bowel cancer screening is crucial to the development and targeting of new approaches and initiatives. PMID: 26859797 [PubMed - as supplied by publisher] (Source: Health Promotion Journal of Australia)
Wed, 10 Feb 2016 06:00:00 +0100(NaturalNews) The U.S. government's policy on cancer is far from perfect. When it comes to this deadly disease, the strategy proposed is simple: chemotherapy, surgery and radiation. Just in the U.S.A, cancer takes the lives of almost 600,000 people every year, making it a significant... (Source: NaturalNews.com)
Mon, 08 Feb 2016 13:30:00 +0100Conclusion This is very early-stage laboratory research that aimed to explore new avenues that could detect and diagnose cancer earlier – and hopefully ultimately lead to earlier and more successful treatment, and so better cancer survival rates. The study indicates taking blood samples and detecting DNA methylation from tumours could be one possible early screening or diagnostic method, and shows this technique's use for indicating womb, lung, stomach, colon and breast tumours. However, there are likely to be many more stages of research necessary to build on these findings and check how reliable the test could be for different subtypes of these cancers, and also whether it could be used for other types of cancer. Even then, there are many things to be taken into account before con...
Mon, 08 Feb 2016 09:12:11 +0100Former community nurse Max Neill, 49, of Preston, who suffers from an incurable form of bowel cancer, came up with the idea for a form helping terminally ill patients leave their final wishes. (Source: the Mail online | Health)
Sat, 06 Feb 2016 00:00:00 +0100ConclusionScreening and non‐screening colonoscopy differ in the GRS domains of completion and pathology detection. These differences need to be acknowledged when comparing screeners and non‐screeners using GRS within units.This article is protected by copyright. All rights reserved. (Source: Colorectal Disease)
Thu, 04 Feb 2016 00:00:00 +0100Conclusions The incidence of SBC has increased in recent decades, mainly because of a large increase in the incidence of duodenal adenocarcinomas, which are also associated with the poorest prognosis. (Source: Journal of Gastroenterology)
Wed, 03 Feb 2016 00:00:00 +0100Rising rates link to economic development, says studyRelated items from OnMedicaWide country and gender differences in bowel cancer deaths across EuropeGene found to be linked to increased risk of recurrence in bowel cancerVegetarians have lower bowel cancer risk than meat-eatersEarly stage bowel cancer more likely to be picked up by screeningNew test prompts rise in bowel screening uptake (Source: OnMedica Latest News)
Wed, 03 Feb 2016 00:00:00 +0100Conclusions: Colonoscopy experience was generally positive, suggesting high satisfaction with the BCSP. Reported pain and unexpected discomfort were more negative than most other outcomes (particularly for women); measures to improve this should be considered.[...]© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Abstract | Full text (Source: Endoscopy)
Tue, 02 Feb 2016 18:34:32 +0100Suzanne Dore, 42, of Rayne, Essex has been living with a colostomy bag for five years but struggles to find clothes that are both stylish and comfortable, so she started her own blog to help other women. (Source: the Mail online | Health)
Tue, 02 Feb 2016 12:01:32 +0100Suzanne Dore, 42, of Rayne, Essex has been living with a colostomy bag for five years but struggles to find clothes that are both stylish and comfortable, so she started her own blog to help other women. (Source: the Mail online | Health)
Tue, 02 Feb 2016 05:00:00 +0100(Cancer Research UK) Almost 40,000 more people might take a bowel cancer test in England each year if the letter inviting them to do so was endorsed by their GP. (Source: EurekAlert! - Cancer)
Tue, 02 Feb 2016 00:00:00 +0100Conclusion Our results suggest that people can accurately report whether they have ever taken part in CRC screening. The vast majority of those whose records were verified could also accurately report whether they had taken part in screening at least twice. They were somewhat less accurate in reporting whether they had responded to all screening invitations. (Source: Journal of Medical Screening)
Tue, 02 Feb 2016 00:00:00 +0100Authors: Rosalind Raine, Stephen W Duffy, Jane Wardle, Francesca Solmi, Stephen Morris, Rosemary Howe, Ines Kralj-Hans, Julia Snowball, Nicholas Counsell, Sue Moss, Allan Hackshaw, Christian von Wagner, Gemma Vart, Lesley M McGregor, Samuel G Smith, Stephen Halloran, Graham Handley, Richard F Logan, Sandra Rainbow, Steve Smith, Mary C Thomas & Wendy Atkin (Source: British Journal of Cancer)
Tue, 02 Feb 2016 00:00:00 +0100Authors: Benjamin Kearns, Sophie Whyte, Helen E Seaman, Julia Snowball, Stephen P Halloran, Piers Butler, Julietta Patnick, Claire Nickerson & Jim Chilcott (Source: British Journal of Cancer)
Mon, 01 Feb 2016 05:00:00 +0100(BMJ) There's a 10-fold difference worldwide in the numbers of new cases of bowel cancer and deaths from the disease, finds research published online in the journal Gut. (Source: EurekAlert! - Cancer)
Sun, 31 Jan 2016 22:57:43 +0100THE DRUG based on Chinese herbal medicine is being trialled on 140 patients in the UK (Source: Daily Express - Health)
Mon, 25 Jan 2016 00:00:00 +0100NHS patients will now get access to a drug which can extend lifeRelated items from OnMedicaImproving cancer diagnosis Early stage bowel cancer more likely to be picked up by screeningNICE approves skin cancer drug in final draft guidanceCancer drug improve Alzheimer’s symptomsExperts find gene fault behind ovarian cancer (Source: OnMedica Latest News)
Fri, 22 Jan 2016 13:34:43 +0100Bowel cancer is more likely to be diagnosed at the earliest stage if it is picked up by screening, according to new figures. (Source: ScienceDaily Headlines)
Fri, 22 Jan 2016 00:00:00 +0100More than one in five cases are late stage by the time people see their GPRelated items from OnMedicaScheme launched to personalise bowel cancer careBowel cancer patients still diagnosed too lateMore than half of new bowel cancer screen test invitees fail to take up offerGene found to be linked to increased risk of recurrence in bowel cancerGPs help in early cancer diagnosis rise (Source: OnMedica Latest News)
Thu, 21 Jan 2016 05:00:00 +0100(Cancer Research UK) Bowel cancer is more likely to be diagnosed at the earliest stage if it is picked up by screening, according to new figures released by Cancer Research UK and Public Health England's National Cancer Intelligence Network today. (Source: EurekAlert! - Cancer)
Tue, 19 Jan 2016 11:30:00 +0100ConclusionThis was an experimental animal study aiming to explore the possible biological mechanism by which obesity may be associated with the development of bowel cancer. The findings suggest it may be down to silencing a particular receptor – GUCY2C – located on the cells lining the bowel. The study found that excessive consumption of fat or carbohydrate in mice was associated with loss of the guanylin hormone responsible for turning on the GUCY2C receptor. Silencing this receptor led to tumour development. Further study confirmed this by showing that using a drug to increase production of guanylin reversed the effects of the high-calorie diet and prevented the mice developing tumours.The findings of this study are of interest and further our understanding of a possible mechanism ...
Mon, 18 Jan 2016 00:00:00 +0100In response to increasing calls to introduce warning labels on alcoholic beverages, this study investigated the potential effectiveness of alcohol warning statements designed to increase awareness of the alcohol–cancer link. A national online survey was administered to a diverse sample of Australian adult drinkers (n = 1,680). Along with attitudinal, intentions and demographic items, the survey included an online simulation that exposed respondents to one of six cancer warning statements delivered across a range of situational contexts. Half of the statements made general reference to cancer and half mentioned specific forms of cancer. Respondents reported on the believability, convincingness and personal relevance of the warning statements. Pre- and post-exposure data were captured ...
Sun, 17 Jan 2016 00:04:02 +0100Authors: Bolin TD, Korman MG, Nicholson F, Pezzullo L, Engelman J, Collings K, Creelman DG PMID: 26763806 [PubMed - in process] (Source: Medical Journal of Australia)
Fri, 15 Jan 2016 09:21:00 +0100WE ALL know carrying extra weight can be bad for your health but is the general public aware there is a link between obesity and cancer? (Source: Daily Express - Health)
Fri, 15 Jan 2016 00:00:00 +0100The UK national screening committee has proposed improvements to screening programmes. (Source: NHS Networks)
Mon, 11 Jan 2016 18:55:05 +0100Glen Williams was left with the huge protuberance after treatment for bowel cancer two years ago (Source: Telegraph Health)
Mon, 11 Jan 2016 15:50:51 +0100Glenn Williams, 67, from Leicester, developed the hernia following complications from bowel cancer surgery. He said his life had been transformed by the pioneering surgery to fix it. (Source: the Mail online | Health)
Tue, 29 Dec 2015 00:00:00 +0100This article is protected by copyright. All rights reserved. PMID: 26712035 [PubMed - as supplied by publisher] (Source: Biology of the Cell)
Wed, 23 Dec 2015 00:00:00 +0100Conclusion This case highlights an unusual but potentially life threatening complication following colonoscopy. Endoscopists and clinicians should be aware of the diagnosis to allow for early recognition and appropriate management. (Source: Annals of Medicine and Surgery)
Wed, 16 Dec 2015 20:50:36 +0100Specialists in Melbourne were better at detecting polyps and adenomas - both of which develop into bowel cancer - during colonoscopies, compared to doctors listening to pop music. (Source: the Mail online | Health)
Tue, 15 Dec 2015 15:08:51 +0100Stephen FellerMELBOURNE, Dec. 15 (UPI) -- Doctors in Australia report listening to the score from "Star Wars" while performing colonoscopies helped them detect bowel cancer in patients. (Source: Health News - UPI.com)
Tue, 15 Dec 2015 00:00:00 +0100Distributional cost-effectiveness analysis (DCEA) is a framework for incorporating health inequality concerns into the economic evaluation of health sector interventions. In this tutorial, we describe the technical details of how to conduct DCEA, using an illustrative example comparing alternative ways of implementing the National Health Service (NHS) Bowel Cancer Screening Programme (BCSP). The 2 key stages in DCEA are 1) modeling social distributions of health associated with different interventions, and 2) evaluating social distributions of health with respect to the dual objectives of improving total population health and reducing unfair health inequality. As well as describing the technical methods used, we also identify the data requirements and the social value judgments that have t...
Thu, 10 Dec 2015 00:00:00 +0100This study is registered, number ISRCTN74121020. Findings As all four trials were embedded in the screening programme, loss to follow-up was minimal (less than 0·5%). Trials 1 (n=163 525) and 2 (n=150 417) showed no effects on the socioeconomic gradient of uptake or overall uptake. Trial 3 (n=265 434) showed no effect on the socioeconomic gradient but was associated with increased overall uptake (adjusted odds ratio [OR] 1·07, 95% CI 1·04–1·10, p<0·0001). In trial 4 (n=168 480) a significant interaction was seen with socioeconomic status gradient (p=0·005), with a stronger effect in the most deprived quintile (adjusted OR 1·11, 95% CI 1·04–1·20, p=0·003) than in the least deprived (1·00, 0·94–1·06, p=0·98). Overall uptake was also increased (1·07, 1·03...
Tue, 08 Dec 2015 00:00:00 +0100Conclusion Patients with celiac disease should be carefully monitored and endoscopic or radiologic investigations should be carried out in patients with any doubtful symptoms. (Source: International Journal of Surgery Case Reports)
Tue, 08 Dec 2015 00:00:00 +0100Of four evidence-based interventions, the enhanced reminder letter reduced the socioeconomic gradient in screening uptake, but further reducing inequalities in screening uptake through written materials alone will be challenging. (Source: LANCET)
Thu, 03 Dec 2015 18:32:30 +0100Irish Cancer Society says wait, which is 12 days for private patients, unacceptable (Source: The Irish Times - Health)
Tue, 01 Dec 2015 00:00:00 +0100Authors: Lateef N, Basit KA, Abbasi N, Kazmi SM, Ansari AB, Shah M Abstract Along with graft vasculopathy, malignancies comprise a major complication after heart transplant, with a rate of occurrence of 39.1% in 10 years. Skin cancers and posttransplant lymphoproliferative disorder are more common in adults, whereas lymphoma is more often shown in children. A major cause of malignancies after heart transplant is the use of increased doses of prophylactics needed during immunosuppressive therapy. Data, however, are scarce regarding the association between a particular immunosuppressive drug and a posttransplant malignancy. Compared with the general population, recipients have a higher incidence of malignancies after heart transplant, with an early onset and more aggressive disease. ...
Tue, 01 Dec 2015 00:00:00 +0100This study looked to evaluate the effectiveness of the NBCSP against this aim. The study linked 2006–2008 NBCSP invitees to colorectal cancer incidence and mortality data and categorized NBCSP invitees diagnosed with colorectal cancer into screen‐detected, interval cancer and nonparticipant subgroups. Colorectal cancers in those not invited into the NBCSP were categorized as the never invited group. Proportional hazards and logistic regression were used to compare mortality, summary stage and other characteristics between groups. Of 12 689 people diagnosed with colorectal cancer in 2006–2008, the never invited group (10 080 cases) had a 15% higher risk of colorectal cancer death by 31 December 2011, compared with NBCSP invitees (after correcting for lead‐time bias). Of the colore...
Mon, 30 Nov 2015 17:00:59 +0100Julia Watson is, in many ways, a typical 41-year-old woman. A happily married mother of four young girls, she lives in Australia, where she juggles her busy family life with simultaneously studying for a diploma. However, in December, 2013, her world suddenly fell apart when she was diagnosed with stage IV bowel cancer. In this raw, honest, and emotive book, she shares her story. (Source: The Lancet Oncology)
Sat, 28 Nov 2015 00:00:00 +0100CONCLUSION monitoring of patients with celiac disease should be careful. Endoscopic or radiologic investigations should be indicated in front of any doubtful symptom. (Source: International Journal of Surgery Case Reports)
Sat, 28 Nov 2015 00:00:00 +0100This study aimed to explore couples' experiences of colorectal (bowel) cancer, focusing on the transition after treatment. (Source: European Journal of Oncology Nursing)
Sat, 28 Nov 2015 00:00:00 +0100CONCLUSIONS: The findings underscore the value of a systemic approach for supporting couples during recovery from colorectal cancer and demonstrate the need for consistency of healthcare provision across the cancer trajectory, including post-treatment. PMID: 26643399 [PubMed - as supplied by publisher] (Source: European Journal of Oncology Nursing)
Fri, 27 Nov 2015 00:00:00 +0100This study will take place across seven NHS Hospital Trusts: one in London and six within the Northern Region Endoscopy Group. A maximum of 10 colonoscopists per site will recruit a total of 1772 patients, with a maximum of four bowel screening colonoscopists permitted per site. Discussion: This is the first trial to evaluate the adenoma detection rate of Endocuff Vision™ in all screening, surveillance, and diagnostic patient groups. This timely study will guide clinicians as to the role of Endocuff Vision™ in routine colonoscopy.Study registration: ISRCTN11821044.[...]© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Abstract | open access Full text (Source: Endoscopy International Open)
Wed, 25 Nov 2015 00:00:00 +0100A report from a national bowel cancer charity sets out five ambitions for the future of bowel cancer care. (Source: NHS Networks)
Mon, 23 Nov 2015 22:50:29 +0100Katie Warrent, Kristal Ford-Spencer and Cassie Ford baffled doctors when they were all diagnosed with cancer within six weeks of each other. Katie with bowel cancer and Kristal and Cassie, breast cancer. (Source: the Mail online | Health)
Mon, 23 Nov 2015 13:52:11 +0100LONDON (Reuters) - Sales of pre-packed sausages and bacon fell sharply at Britain's top grocers in the weeks following publication of a World Health Organisation (WHO) report, which said eating processed meat can cause bowel cancer, data published on Monday showed. (Source: Reuters: Health)
Fri, 20 Nov 2015 10:50:04 +0100CONCLUSION: The characteristics of the patients were generally consistent with those described in the literature. Capsule endoscopy and balloon assisted enteroscopy are useful in the diagnosis, management and surveillance of small bowel cancer. PMID: 26574979 [PubMed - as supplied by publisher] (Source: Acta Medica Portuguesa)
Wed, 11 Nov 2015 00:00:00 +0100Authors: Abstract Women with naturally higher levels of oestrogen are less likely to develop bowel cancer after menopause than women with low levels, new study results suggest. PMID: 26554968 [PubMed - in process] (Source: Nursing Standard)
Sun, 08 Nov 2015 12:26:53 +0100BBC presenter George Alagiah's world crumbled when he was diagnosed with 'stage four' bowel cancer in April 2014. But on Tuesday, he will return to the nation's screens on the Six O'Clock News. (Source: the Mail online | Health)
Sat, 07 Nov 2015 00:00:00 +0100ConclusionThe UK bowel cancer awareness campaigns appear to have improved public awareness of CRC and encouraged symptomatic individuals to seek urgent medical attention. The increase in 2WW referrals has not translated into better survival for symptomatic patients, partly due to the proportion presenting with advanced disease. (Source: Colorectal Disease)
Fri, 06 Nov 2015 00:00:00 +0100ConclusionsCMMRD is rare, but, especially in areas where founder mutations for LS and consanguinity are common, pediatricians should be aware of it since they are the first to encounter these children. Early diagnosis will enable tailored cancer surveillance in the entire family and a discussion regarding prenatal genetic diagnosis. (Source: Pediatric Blood and Cancer)
Thu, 05 Nov 2015 00:00:00 +0100Publication date: Available online 4 November 2015 Source:Clinics and Research in Hepatology and Gastroenterology Author(s): Yosra Zaaimi, Thomas Aparicio, Pierre Laurent-Puig, Julien Taieb, Aziz Zaanan Small bowel cancer represents less than 5% of all gastrointestinal cancers, while small bowel adenocarcinoma (SBA) accounts for about one third of all cancers of the small bowel. Although SBA frequently appears sporadically, some diseases are risk factors, such as Crohn's disease and some genetic predispositions to cancer. Progress in the identification of molecular alterations suggests some similarities in carcinogenesis between SBA and colorectal cancer. Evidence levels for the treatment and prognosis of these tumors are insufficient because of the scarcity of this disease and the ...
Wed, 04 Nov 2015 00:00:00 +0100Authors: Zaaimi Y, Aparicio T, Laurent-Puig P, Taieb J, Zaanan A Abstract Small bowel cancer represents less than 5% of all gastrointestinal cancers, while small bowel adenocarcinoma (SBA) accounts for about one third of all cancers of the small bowel. Although SBA frequently appears sporadically, some diseases are risk factors, such as Crohn's disease and some genetic predispositions to cancer. Progress in the identification of molecular alterations suggests some similarities in carcinogenesis between SBA and colorectal cancer. Evidence levels for the treatment and prognosis of these tumors are insufficient because of the scarcity of this disease and the absence of randomized trials. Chemotherapy based on fluoropyrimidine plus a platinum salt appears to be the most effective treat...
Tue, 03 Nov 2015 19:07:57 +0100Unless you've been hiding under a rock, you'll know that earlier this week the World Health Organization declared processed meat as definitively carcinogenic to humans and red meat as "probably" carcinogenic. As a nutritionist and an avid follower of dietary trends and analysis, I found this one interesting. Vegetarians and vegans rejoiced and the media cranked out a combination of sensationalist and alarmist headlines. Carnivores wept and twitter became the venue for massive amounts of bacon-related defiance and hilarity: @thepunningman "In your face, World Health Organisation. The bacon I bought this morning said it was cured." So I started to investigate, trying to find some objectivity in amongst all the hysteria. An unexpected part of my job has to become a voice of reason in dietary...
Mon, 02 Nov 2015 08:45:56 +0100Scientists warn that just two portions a week increases the risk by almost a fifth (Source: Telegraph Health)
Thu, 29 Oct 2015 13:50:01 +0100[News24Wire] A review of around 800 epidemiological studies by the WHO's International Agency for Research on Cancer (IARC), released on Monday 25 October, showed that eating processed meats like hot dogs, biltong, sausages or bacon can lead to bowel cancer in humans. (Source: AllAfrica News: Health and Medicine)
Wed, 28 Oct 2015 07:00:28 +0100A major study shows that the chance of an early cancer diagnosis is 20 per cent higher in some parts of the country, compared with others (Source: Telegraph Health)
Wed, 28 Oct 2015 00:00:00 +0100Cancer Research UK reveals that a patient’s chances of early diagnosis varies according to where they liveRelated items from OnMedicaNHS tests system for cancer diagnosis is failing More than half of new bowel cancer screen test invitees fail to take up offerNICE guidance aims at earlier cancer diagnosis by GPsTwo-week urgent referrals for suspected cancer linked to lower death rates £400m cancer revamp calls for speedy GP referral (Source: OnMedica Latest News)
Tue, 27 Oct 2015 17:07:16 +0100Eating just 50g a day of processed meats increases the risk of bowel cancer by 18 per cent, the World Health Organisation report said. 50g a day includes half a hot dog or 1.7 shop bought meatballs... (Source: the Mail online | Health)
Tue, 27 Oct 2015 11:48:16 +0100New research shows an increased risk of large bowel cancer for each 1 cm rise in waist circumference. In addition, in men, there is now evidence that increasing waist circumference in middle age is associated with increased bowel cancer risk. (Source: ScienceDaily Headlines)
Tue, 27 Oct 2015 11:10:00 +0100What is the issue? "Processed meat ranks alongside smoking as major cause of cancer, World Health Organisation [WHO] says," The Daily Telegraph reports. They have been ranked as a group one carcinogen – the same ranking as cigarettes, alcohol and asbestos. The WHO's International Agency for Research on Cancer (IARC) released a report evaluating the link between the consumption of red and processed meat and cancer. A question and answer factsheet was also published. The report explained red meat refers to unprocessed meat such as beef, veal, pork and lamb, while processed meat has been transformed through salting, curing, fermentation, smoking, or other processes. The largest body of evidence is for the link with colorectal (bowel) cancer. How was the report received by t...
Tue, 27 Oct 2015 04:00:00 +0100(Spink Health) New research shows an increased risk of large bowel cancer for each 1 cm rise in waist circumference. In addition, in men, there is now evidence that increasing waist circumference in middle age is associated with increased bowel cancer risk. (Source: EurekAlert! - Cancer)
Tue, 27 Oct 2015 00:27:40 +0100World Health Organisation finds processed meats such as sausages and ham carry an increased risk of bowel cancer, and red meat ‘probably’ does tooAustralians do not need to stop eating red meat but should limit their intake, say experts responding to international research showing it can increase the risks for certain types of cancer. Related: Barnaby Joyce plays down research linking processed meats to cancer Continue reading... (Source: Guardian Unlimited Science)
Mon, 26 Oct 2015 14:24:46 +0100PARIS (Reuters) - Eating processed meats like hot dogs, sausages or bacon can lead to bowel cancer in humans and red meat is a likely cause of the disease, World Health Organisation (WHO) experts said. (Source: Reuters: Health)
Mon, 26 Oct 2015 12:30:51 +0100UN health body says bacon, sausages and ham among most carcinogenic substances along with cigarettes, alcohol, asbestos and arsenicBacon, ham and sausages rank alongside cigarettes as a major cause of cancer, the World Health Organisation has said, placing cured and processed meats in the same category as asbestos, alcohol, arsenic and tobacco.The report from the WHO’s International Agency for Research on Cancer said there was enough evidence to rank processed meats as group 1 carcinogens because of a causal link with bowel cancer. Continue reading... (Source: Guardian Unlimited Science)
Mon, 26 Oct 2015 11:46:31 +0100Very sad news for bacon lovers. The World Health Organization announced Monday that cured and processed meats like bacon, sausage, hot dogs and ham cause cancer, adding the foods to a top-tier list of carcinogenic substances that includes alcohol, cigarettes, asbestos, and arsenic. Processed meats can be bundled with these threatening carcinogens because of their link with bowel cancer, according to a report from WHO's International Agency for Research on Cancer, though their inclusion doesn't mean that bacon causes cancer at the same rate as, say, smoking. "For an individual, the risk of developing colorectal (bowel) cancer because of their consumption of processed meat remains small, but this risk increases with the amount of meat consumed," IARC epidemiologist Dr. K...
Mon, 26 Oct 2015 11:33:55 +0100WHO experts said eating processed meat can cause bowel cancer in humans while red meat is a likely cause of the disease. (Source: The Economic Times)
Mon, 26 Oct 2015 11:31:46 +0100Red meat also classified as a ‘probable’ carcinogen, in findings that could sharpen debate over meat-based diets (Source: The Irish Times - Health)
Mon, 26 Oct 2015 11:31:46 +0100Red meat also classified as a ‘probable’ carcinogen, in findings that could sharpen debate over meat-based diets (Source: The Irish Times - Health)
Mon, 26 Oct 2015 00:00:00 +0100Both red and processed meat heighten riskRelated items from OnMedicaDeep-fried foods linked to prostate cancerEating processed meat raises risk of premature deathBig rise in bowel cancer among older menHealthy diet linked to lower COPD riskBreast cancer risk may rise with red meat intake (Source: OnMedica Latest News)
Thu, 22 Oct 2015 15:18:34 +0100EXCLUSIVE: The 'scaremongering' over the link between red meat and cancer is based on 'notoriously inaccurate' dietary studies, says Roger Leicester, of St George's Hospital, London. (Source: the Mail online | Health)
Sat, 17 Oct 2015 00:00:00 +0100Bowel cancer patients with the gene are likely to have shorter survivalRelated items from OnMedicaNew test prompts rise in bowel screening uptakeBowel cancer patients still diagnosed too lateScreening drop-out rate higher after abnormal FOB testScheme launched to personalise bowel cancer careBreakthrough in pancreatic cancer diagnosis (Source: OnMedica Latest News)
Fri, 16 Oct 2015 07:00:00 +0100A newly discovered gene, which appears to indicate whether a patient's bowel cancer is likely to recur, could lead to more personalized treatment. (Source: Health News from Medical News Today)
Thu, 15 Oct 2015 04:00:00 +0100(BMJ) Scientists have discovered a new gene linked to an increased risk of bowel cancer recurrence and shortened survival, reveals research in the journal Gut. (Source: EurekAlert! - Cancer)
Wed, 14 Oct 2015 16:05:00 +0100Conclusion Based on genes, the findings of this study allowed researchers to broadly classify colorectal cancer into four main types: CMS1, CMS2, CMS3 and CMS4. To address the issue of inconsistent reporting of colorectal cancer types, researchers from different parts of the world formed an international consortium dedicated to large-scale data sharing and analysis. They pooled pre-existing data on gene expression from colorectal cancer patients to assess the previously published colorectal cancer types. While this study extends our understanding of the different types of colorectal cancer and in the future may lead to more targeted treatments for better outcomes, the results must be interpreted with caution. The study does have strengths in its large sample size. However, although rese...
Tue, 13 Oct 2015 03:39:22 +0100, each with a different prognosis, scientists have discovered. (Source: BBC News | Health | UK Edition)
Mon, 12 Oct 2015 19:51:30 +0100The discovery may lead to doctors treating each type of disease differently, and assist the development of more targeted drugs, say scientists from the Institute of Cancer Research, London. (Source: the Mail online | Health)
Mon, 12 Oct 2015 04:00:00 +0100(Institute of Cancer Research) Bowel cancer can be divided up into four distinct diseases, each with its own set of biological characteristics, a major new study reports. The research could allow doctors to treat each type of bowel cancer differently - and drive the design of distinct sets of targeted drugs for each type. (Source: EurekAlert! - Cancer)
Sun, 11 Oct 2015 04:00:00 +0100(University of Melbourne) A new study into rates of bowel (colorectal) cancer in Europe reveals a significant reduction in deaths from the disease in women, but more deaths in men. (Source: EurekAlert! - Cancer)
Fri, 09 Oct 2015 12:28:30 +0100Wil Handford, 24, of Barrowford, Lancashire, died on Wednesday night. He was diagnosed with cancer in 2014 after losing 2st in a matter of weeks, struggling to eat and suffering stomach pains. (Source: the Mail online | Health)
Wed, 07 Oct 2015 00:00:00 +0100This is despite overall falls in rates across the regionRelated items from OnMedicaScheme launched to personalise bowel cancer careBowel cancer patients still diagnosed too lateReport reveals ‘alarming’ death rate for bowel surgeryMore than half of new bowel cancer screen test invitees fail to take up offerSurviving colorectal cancer twice as likely after surgery (Source: OnMedica Latest News)
Tue, 06 Oct 2015 04:00:00 +0100(Cancer Research UK) Thousands more people would take part in bowel cancer screening if the kit included extras, such as gloves and 'poo catchers,' according to a Cancer Research UK study published Wednesday in Biomed Research International. (Source: EurekAlert! - Medicine and Health)
Tue, 06 Oct 2015 04:00:00 +0100(BMJ) Over the past 40 years, deaths from bowel (colorectal) cancer have been falling in an increasing number of European countries. Yet considerable disparities still exist between men and women and between specific regions in Europe, finds a study in The BMJ this week. (Source: EurekAlert! - Cancer)