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Last Build Date: Mon, 30 Jan 2017 21:27:52 +0000

 



From de novo protein design to molecular machine systems

Mon, 30 Jan 2017 21:25:28 +0000

A review from the group leading recent rapid progress in de novo protein design describes the successes, identifies the remaining challenges, and heralds the advance "from the Stone Age to the Iron Age" in protein design.



Two-component, 120-subunit icosahedral cage extends protein nanotechnology

Sat, 28 Jan 2017 23:32:59 +0000

Ten designs spanning three types of icosahedral architectures produce atomically precise multi-megadalton protein cages to deliver biological cargo or serve as scaffolds for organizing various molecular functions.



Cleanly placing atomically precise graphene nanoribbons

Mon, 23 Jan 2017 23:25:05 +0000

Atomically precise chevron-shaped graphene nanoribbons were purified after solution synthesis, cleanly placed by dry contact transfer on a hydrogen-passivated Si surface, imaged and manipulated by scanning tunneling microscopy, and covalently bonded to depassivated surface positions.



Designing novel protein backbones through digital evolution

Tue, 17 Jan 2017 18:12:50 +0000

Computational recombination of small elements of structure from known protein structures generates a vast library of designs that balance protein stability with the potential for new functions and novel interactions.



Adding modular hydrogen-bond networks to protein design

Sun, 15 Jan 2017 23:58:28 +0000

Computer designed networks of hydrogen bonds allow programming specific interactions of protein interfaces, facilitating programming molecular recognition.



A brief history of nanotechnology

Tue, 03 Jan 2017 21:35:04 +0000

A historian looks at nanotechnology as utopian or dystopian vision, real-life research and development, and why emerging technologies are such compelling topics.



New Funding Opportunity from U.S. DOE

Mon, 02 Jan 2017 04:05:51 +0000

A new funding opportunity from the Advanced Manufacturing Office, U.S. Department of Energy, incudes a subtopic on Atomically Precise Manufacturing



DOE office focusing on atomically precise manufacturing

Sun, 01 Jan 2017 04:01:03 +0000

Longtime Foresight member Dave Forrest is leading DOE's Advanced Manufacturing Office in advocating atomically precise manufacturing to transform the U.S. manufacturing base.



Nobel Prize in Chemistry recognizes molecular machines

Mon, 10 Oct 2016 21:38:45 +0000

Sir J. Fraser Stoddart, winner of 2007 Foresight Feynman Prize for Experiment, shares the 2016 Chemistry Nobel for the design and synthesis of molecular machines.



Assembling a large, stable, icosahedral protein molecular cage

Fri, 09 Sep 2016 23:29:49 +0000

A trimeric protein was designed to self assemble into a 60 unit icosahedron with a roomy interior that might find use to ferry molecular cargo into cells or as a chemical reactor.