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Preview: Organic Process Research & Development: Latest Articles (ACS Publications)

Organic Process Research & Development: Latest Articles (ACS Publications)



latest articles published in Organic Process Research & Development



Copyright: Copyright 2017 American Chemical Society
 



Technoeconomic Evaluation of Multiple Mixed Suspension-Mixed Product Removal (MSMPR) Crystallizer Configurations for Continuous Cyclosporine Crystallization

Fri, 22 Sep 2017 04:15:13 GMT2017-09-22T04:15:13Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00225
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Process Development for the Synthesis of a Selective M1 and M4 Muscarinic Acetylcholine Receptors Agonist

Wed, 20 Sep 2017 17:11:00 GMT2017-09-20T17:11:00Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00236
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A Fully Continuous-Flow Process for the Synthesis of p-Cresol: Impurity Analysis and Process Optimization

Tue, 19 Sep 2017 17:50:22 GMT2017-09-19T17:50:22Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00250
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Development of a General Protocol To Prepare 2H-1,3-Benzoxazine Derivatives

Sat, 16 Sep 2017 12:00:10 GMT2017-09-16T12:00:10Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00209
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Rapid Turn-On Fluorescence Detection of Copper(II): Aromatic Substituent Effects on the Response Rate

Fri, 15 Sep 2017 13:06:08 GMT2017-09-15T13:06:08Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00269
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Use of a Polymer Additive To Enhance Impurity Rejection in the Crystallization of a Pharmaceutical Compound

Thu, 14 Sep 2017 14:50:19 GMT2017-09-14T14:50:19Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00145
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Highly Productive Continuous Flow Synthesis of Di- and Tripeptides in Water

Thu, 14 Sep 2017 14:49:41 GMT2017-09-14T14:49:41Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00214
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Potential Safety Hazards Associated with Using Acetonitrile and a Strong Aqueous Base

Thu, 14 Sep 2017 14:48:05 GMT2017-09-14T14:48:05Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00158
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Optimized Synthetic Route for Enantioselective Preparation of (S)-Metolachlor from Commercially Available (R)-Propylene Oxide

Tue, 12 Sep 2017 18:58:01 GMT2017-09-12T18:58:01Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00216
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The First Asymmetric Pilot-Scale Synthesis of TV-45070

Fri, 08 Sep 2017 15:37:56 GMT2017-09-08T15:37:56Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00237
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Development of a Safe Continuous Manufacturing Route to 2-(4-Isopropyl-1H-1,2,3-triazol-1-yl)acetic Acid

Fri, 08 Sep 2017 15:37:38 GMT2017-09-08T15:37:38Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00259
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Optimization of Manganese Coupling Reaction for Kilogram-Scale Preparation of Two Aryl-1,3-dione Building Blocks

Fri, 08 Sep 2017 14:26:36 GMT2017-09-08T14:26:36Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00241
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Eco-Friendly and Industrially Scalable Synthesis of the Sex Pheromone of Lobesia botrana. Important Progress for the Eco-Protection of Vineyard

Tue, 05 Sep 2017 17:33:14 GMT2017-09-05T17:33:14Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00206
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Development of a Kilogram-Scale Process for the Enantioselective Synthesis of 3-Isopropenyl-cyclohexan-1-one via Rh/DTBM-SEGPHOS-Catalyzed Asymmetric Hayashi Addition Enabled by 1,3-Diol Additives

Tue, 05 Sep 2017 04:42:46 GMT2017-09-05T04:42:46Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00253
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Microfluidic Synthesis of tert-Butyl Peresters via KI-Catalyzed Oxidative Coupling of Methyl Arenes and tert-Butyl Hydroperoxide

Fri, 01 Sep 2017 18:17:49 GMT2017-09-01T18:17:49Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00248
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Synthesis of Enantiomerically Pure N-Acyl Amino Nitriles via Catalytic Dehydration of Oximes and Application in a de Novo Synthesis of Vildagliptin

Fri, 01 Sep 2017 15:21:27 GMT2017-09-01T15:21:27Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00169
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Development of a Practical Enzymatic Process for Preparation of (S)-2-Chloro-1-(3,4-difluorophenyl)ethanol

Fri, 01 Sep 2017 13:25:24 GMT2017-09-01T13:25:24Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00230
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The Development and Scale-Up of an Antibody Drug Conjugate Tubulysin Payload

Tue, 29 Aug 2017 15:08:34 GMT2017-08-29T15:08:34Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00232
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Development of Pharmaceutically Acceptable Crystalline Forms of Drug Substances via Solid-State Solvent Exchange

Fri, 25 Aug 2017 12:32:10 GMT2017-08-25T12:32:10Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00114
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Fmoc-Amox, A Suitable Reagent for the Introduction of Fmoc

Thu, 24 Aug 2017 17:43:27 GMT2017-08-24T17:43:27Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00199
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Continuous Preparation and Use of Dibromoformaldoxime as a Reactive Intermediate for the Synthesis of 3-Bromoisoxazolines

Tue, 22 Aug 2017 13:17:56 GMT2017-08-22T13:17:56Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00229
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Multistep Flow Synthesis of Diazepam Guided by Droplet-Accelerated Reaction Screening with Mechanistic Insights from Rapid Mass Spectrometry Analysis

Tue, 22 Aug 2017 13:16:37 GMT2017-08-22T13:16:37Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00218
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Solubility and Crystallization Process of 2,2,6,6-Tetramethyl-4-piperidinol (TMP)

Mon, 21 Aug 2017 20:07:57 GMT2017-08-21T20:07:57Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00131
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Concise Synthesis of Key Intermediates of Pyriftalid and Paquinimod via Hydrogenation Method

Mon, 21 Aug 2017 18:46:39 GMT2017-08-21T18:46:39Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00177
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From Drying Kinetics, Solvate Structure, Particle Morphology, and Modeling to Optimal Drying Protocol

Mon, 21 Aug 2017 14:20:28 GMT2017-08-21T14:20:28Z

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Organic Process Research & Development
DOI: 10.1021/acs.oprd.7b00162
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