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Preview: ACS Chemical Biology: Latest Articles (ACS Publications)

ACS Chemical Biology: Latest Articles (ACS Publications)



latest articles published in ACS Chemical Biology



Copyright: Copyright 2016 American Chemical Society
 



Catalytic Promiscuity of O-GlcNAc Transferase Enables Unexpected Metabolic Engineering of Cytoplasmic Proteins with 2-Azido-2-deoxy-glucose

Fri, 09 Dec 2016 16:16:27 GMT2016-12-09T16:16:27Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00876
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Histone Ketoamide Adduction by 4-Oxo-2-nonenal Is a Reversible Posttranslational Modification Regulated by Sirt2

Wed, 07 Dec 2016 19:14:33 GMT2016-12-07T19:14:33Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00713
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Live Cell Imaging of Endogenous mRNA Using RNA-Based Fluorescence “Turn-On” Probe

Wed, 07 Dec 2016 05:27:33 GMT2016-12-07T05:27:33Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00586
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Assigning the Algal Source of Dimethylsulfide Using a Selective Lyase Inhibitor

Tue, 06 Dec 2016 16:06:57 GMT2016-12-06T16:06:57Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00844
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What Can We Learn from Bioactivity Data? Chemoinformatics Tools and Applications in Chemical Biology Research

Mon, 05 Dec 2016 21:33:05 GMT2016-12-05T21:33:05Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00706
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Disruption of Mycobacterial AftB Results in Complete Loss of Terminal β(1 → 2) Arabinofuranose Residues of Lipoarabinomannan

Mon, 05 Dec 2016 15:33:29 GMT2016-12-05T15:33:29Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00898
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Observing Biosynthetic Activity Utilizing Next Generation Sequencing and the DNA Linked Enzyme Coupled Assay

Mon, 05 Dec 2016 15:15:28 GMT2016-12-05T15:15:28Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00652
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Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis

Fri, 02 Dec 2016 16:42:47 GMT2016-12-02T16:42:47Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00849
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Sudemycin K: A Synthetic Antitumor Splicing Inhibitor Variant with Improved Activity and Versatile Chemistry

Thu, 01 Dec 2016 05:34:11 GMT2016-12-01T05:34:11Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00562
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Mapping the Phosphorylation Pattern of Drosophila melanogaster RNA Polymerase II Carboxyl-Terminal Domain Using Ultraviolet Photodissociation Mass Spectrometry

Thu, 01 Dec 2016 16:54:17 GMT2016-12-01T16:54:17Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00729
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Structure and Function of a C–C Bond Cleaving Oxygenase in Atypical Angucycline Biosynthesis

Wed, 30 Nov 2016 05:53:51 GMT2016-11-30T05:53:51Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00621
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Phenotypic Screen for Cardiac Regeneration Identifies Molecules with Differential Activity in Human Epicardium-Derived Cells versus Cardiac Fibroblasts

Wed, 30 Nov 2016 15:03:43 GMT2016-11-30T15:03:43Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00683
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Genome Mining of Amino Group Carrier Protein-Mediated Machinery: Discovery and Biosynthetic Characterization of a Natural Product with Unique Hydrazone Unit

Wed, 30 Nov 2016 13:47:44 GMT2016-11-30T13:47:44Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00818
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Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering

Tue, 29 Nov 2016 05:47:47 GMT2016-11-29T05:47:47Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00732
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An Advance in Prescription Opioid Vaccines: Overdose Mortality Reduction and Extraordinary Alteration of Drug Half-Life

Tue, 29 Nov 2016 16:39:51 GMT2016-11-29T16:39:51Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00977
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Complete Tetrasaccharide Repeat Unit Biosynthesis of the Immunomodulatory Bacteroides fragilis Capsular Polysaccharide A

Mon, 28 Nov 2016 15:58:55 GMT2016-11-28T15:58:55Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00931
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Targeting NF-κB p65 with a Helenalin Inspired Bis-electrophile

Mon, 28 Nov 2016 15:58:21 GMT2016-11-28T15:58:21Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00751
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Structure Based Substrate Specificity Analysis of Heparan Sulfate 6-O-Sulfotransferases

Tue, 22 Nov 2016 19:49:21 GMT2016-11-22T19:49:21Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00841
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Activation Pathway of a Nucleoside Analog Inhibiting Respiratory Syncytial Virus Polymerase

Tue, 22 Nov 2016 12:35:39 GMT2016-11-22T12:35:39Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00788
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An Effective Bacterial Fucosidase for Glycoprotein Remodeling

Fri, 18 Nov 2016 18:52:47 GMT2016-11-18T18:52:47Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00821
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A Malaria Transmission-Blocking (+)-Usnic Acid Derivative Prevents Plasmodium Zygote-to-Ookinete Maturation in the Mosquito Midgut

Thu, 17 Nov 2016 20:38:07 GMT2016-11-17T20:38:07Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00902
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Elucidating the Rimosamide-Detoxin Natural Product Families and Their Biosynthesis Using Metabolite/Gene Cluster Correlations

Tue, 15 Nov 2016 18:00:23 GMT2016-11-15T18:00:23Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00779
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Probing the Catalytic Charge-Relay System in Alanine Racemase with Genetically Encoded Histidine Mimetics

Tue, 15 Nov 2016 18:00:22 GMT2016-11-15T18:00:22Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00940
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A Cell-Permeable Biscyclooctyne As a Novel Probe for the Identification of Protein Sulfenic Acids

Fri, 11 Nov 2016 18:29:12 GMT2016-11-11T18:29:12Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00742
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Interrogating Key Positions of Size-Reduced TALE Repeats Reveals a Programmable Sensor of 5-Carboxylcytosine

Thu, 10 Nov 2016 18:57:53 GMT2016-11-10T18:57:53Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00627
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ATP Recycling with Cell Lysate for Enzyme-Catalyzed Chemical Synthesis, Protein Expression and PCR

Thu, 10 Nov 2016 05:10:46 GMT2016-11-10T05:10:46Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00838
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Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition

Thu, 10 Nov 2016 15:51:01 GMT2016-11-10T15:51:01Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00677
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Native Design of Soluble, Aggregation-Resistant Bioactive Peptides: Chemical Evolution of Human Glucagon

Tue, 08 Nov 2016 05:06:21 GMT2016-11-08T05:06:21Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00923
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Phenyl Glycolipids with Different Glycosyl Groups Exhibit Marked Differences in Murine and Human iNKT Cell Activation

Tue, 08 Nov 2016 15:54:36 GMT2016-11-08T15:54:36Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00650
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Comprehensive Analysis of a Novel Ketoreductase for Pentangular Polyphenol Biosynthesis

Tue, 08 Nov 2016 14:44:00 GMT2016-11-08T14:44:00Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00658
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Temporal Analysis of PP2A Phosphatase Activity During Insulin Stimulation Using a Direct Activity Probe

Mon, 07 Nov 2016 21:36:01 GMT2016-11-07T21:36:01Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00697
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Host Cell Interactions Are a Significant Barrier to the Clinical Utility of Peptide Antibiotics

Mon, 07 Nov 2016 16:10:03 GMT2016-11-07T16:10:03Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00843
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Chemical Proteomics and Structural Biology Define EPHA2 Inhibition by Clinical Kinase Drugs

Mon, 07 Nov 2016 15:44:50 GMT2016-11-07T15:44:50Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00709
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Deciphering Piperidine Formation in Polyketide-Derived Indolizidines Reveals a Thioester Reduction, Transamination, and Unusual Imine Reduction Process

Thu, 03 Nov 2016 15:36:08 GMT2016-11-03T15:36:08Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00875
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Nitrilase-Activatable Noncanonical Amino Acid Precursors for Cell-Selective Metabolic Labeling of Proteomes

Wed, 02 Nov 2016 15:42:53 GMT2016-11-02T15:42:53Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00765
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A TPX2 Proteomimetic Has Enhanced Affinity for Aurora-A Due to Hydrocarbon Stapling of a Helix

Tue, 01 Nov 2016 05:26:04 GMT2016-11-01T05:26:04Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00727
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Quantitative Chemical Proteomic Profiling of Ubiquitin Specific Proteases in Intact Cancer Cells

Mon, 31 Oct 2016 15:47:05 GMT2016-10-31T15:47:05Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00766
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Molecular Mechanism for Isoform-Selective Inhibition of Acyl Protein Thioesterases 1 and 2 (APT1 and APT2)

Mon, 31 Oct 2016 12:33:51 GMT2016-10-31T12:33:51Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00720
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Development of Rare Bacterial Monosaccharide Analogs for Metabolic Glycan Labeling in Pathogenic Bacteria

Fri, 28 Oct 2016 12:16:28 GMT2016-10-28T12:16:28Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00790
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Ligand Optimization by Improving Shape Complementarity at a Hepatitis C Virus RNA Target

Thu, 27 Oct 2016 19:28:18 GMT2016-10-27T19:28:18Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00687
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Diazo Compounds: Versatile Tools for Chemical Biology

Wed, 26 Oct 2016 19:27:57 GMT2016-10-26T19:27:57Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00810
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Characterization of Hedgehog Acyltransferase Inhibitors Identifies a Small Molecule Probe for Hedgehog Signaling by Cancer Cells

Tue, 25 Oct 2016 21:28:17 GMT2016-10-25T21:28:17Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00896
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Immune Response Modulation of Conjugated Agonists with Changing Linker Length

Tue, 25 Oct 2016 18:51:56 GMT2016-10-25T18:51:56Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00895
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The Plasma Protein Binding Proteome of Ertapenem: A Novel Compound-Centric Proteomic Approach for Elucidating Drug–Plasma Protein Binding Interactions

Tue, 25 Oct 2016 14:43:11 GMT2016-10-25T14:43:11Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00700
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Discovery and Characterization of Allosteric WNK Kinase Inhibitors

Wed, 19 Oct 2016 15:11:30 GMT2016-10-19T15:11:30Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00511
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Domain Organization and Active Site Architecture of a Polyketide Synthase C-methyltransferase

Tue, 18 Oct 2016 21:17:56 GMT2016-10-18T21:17:56Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00759
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Boc3Arg-Linked Ligands Induce Degradation by Localizing Target Proteins to the 20S Proteasome

Tue, 18 Oct 2016 05:03:16 GMT2016-10-18T05:03:16Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00656
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K-CLASP: A Tool to Identify Phosphosite Specific Kinases and Interacting Proteins

Mon, 17 Oct 2016 05:25:26 GMT2016-10-17T05:25:26Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00289
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A Unique Mdm2-Binding Mode of the 3-Pyrrolin-2-one- and 2-Furanone-Based Antagonists of the p53-Mdm2 Interaction

Mon, 17 Oct 2016 16:12:13 GMT2016-10-17T16:12:13Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00596
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Click-MS: Tagless Protein Enrichment Using Bioorthogonal Chemistry for Quantitative Proteomics

Mon, 17 Oct 2016 15:09:15 GMT2016-10-17T15:09:15Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00520
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Chemically-Modified Peptides Targeting the PDZ Domain of GIPC as a Therapeutic Approach for Cancer

Tue, 10 Mar 2015 05:40:22 GMT2015-03-10T05:40:22Z

ACS Chemical Biology
DOI: 10.1021/cb500865a
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