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ACS Chemical Biology: Latest Articles (ACS Publications)



latest articles published in ACS Chemical Biology



Copyright: Copyright 2017 American Chemical Society
 



Rational Redesign of a Functional Protein Kinase-Substrate Interaction

Wed, 29 Mar 2017 12:00:11 GMT2017-03-29T12:00:11Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00089
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Recruitment and Regulation of the Non-ribosomal Peptide Synthetase Modifying Cytochrome P450 Involved in Nikkomycin Biosynthesis

Tue, 28 Mar 2017 18:12:43 GMT2017-03-28T18:12:43Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00081
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The Macrolide Toxin Mycolactone Promotes Bim-Dependent Apoptosis in Buruli Ulcer through Inhibition of mTOR

Mon, 27 Mar 2017 19:49:41 GMT2017-03-27T19:49:41Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00053
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Histo-Blood Group Antigen Presentation Is Critical for Binding of Norovirus VLP to Glycosphingolipids in Model Membranes

Mon, 27 Mar 2017 19:48:46 GMT2017-03-27T19:48:46Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00152
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Tracing Effects of Fluorine Substitutions on G-Quadruplex Conformational Changes

Mon, 27 Mar 2017 19:47:44 GMT2017-03-27T19:47:44Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01096
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Stepwise Loop Insertion Strategy for Active Site Remodeling to Generate Novel Enzyme Functions

Mon, 27 Mar 2017 19:45:48 GMT2017-03-27T19:45:48Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00018
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An Unusual Flavin-Dependent Halogenase from the Metagenome of the Marine Sponge Theonella swinhoei WA

Fri, 24 Mar 2017 17:01:00 GMT2017-03-24T17:01:00Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01115
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New Ulvan-Degrading Polysaccharide Lyase Family: Structure and Catalytic Mechanism Suggests Convergent Evolution of Active Site Architecture

Thu, 23 Mar 2017 04:03:32 GMT2017-03-23T04:03:32Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00126
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Selective Downregulation of JAK2 and JAK3 by an ATP-Competitive pan-JAK Inhibitor

Wed, 22 Mar 2017 14:52:23 GMT2017-03-22T14:52:23Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00116
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Novel Peptides Derived from Dengue Virus Capsid Protein Translocate Reversibly the Blood–Brain Barrier through a Receptor-Free Mechanism

Tue, 21 Mar 2017 04:33:41 GMT2017-03-21T04:33:41Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00087
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A Chemical Probe Strategy for Interrogating Inhibitor Selectivity Across the MEK Kinase Family

Mon, 20 Mar 2017 20:26:58 GMT2017-03-20T20:26:58Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01060
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Proteolysis-Targeting Chimeras: Induced Protein Degradation as a Therapeutic Strategy

Mon, 20 Mar 2017 15:29:36 GMT2017-03-20T15:29:36Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01068
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Meeting Proceedings ICBS2016Translating the Power of Chemical Biology to Clinical Advances

Fri, 17 Mar 2017 11:41:29 GMT2017-03-17T11:41:29Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00205
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Mechanism-Based Inhibition of the Mycobacterium tuberculosis Branched-Chain Aminotransferase by d- and l-Cycloserine

Thu, 16 Mar 2017 11:17:36 GMT2017-03-16T11:17:36Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00142
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Discovery of an Extended Austinoid Biosynthetic Pathway in Aspergillus calidoustus

Wed, 15 Mar 2017 15:20:24 GMT2017-03-15T15:20:24Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00003
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Glycation of Lysozyme by Glycolaldehyde Provides New Mechanistic Insights in Diabetes-Related Protein Aggregation

Tue, 14 Mar 2017 15:43:01 GMT2017-03-14T15:43:01Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01103
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Biased Signaling by Agonists of Protease Activated Receptor 2

Tue, 14 Mar 2017 13:39:17 GMT2017-03-14T13:39:17Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01088
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A Fluorescent Probe Distinguishes between Inhibition of Early and Late Steps of Lipopolysaccharide Biogenesis in Whole Cells

Thu, 09 Mar 2017 19:03:51 GMT2017-03-09T19:03:51Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00159
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Mapping Novel Metabolic Nodes Targeted by Anti-Cancer Drugs that Impair Triple-Negative Breast Cancer Pathogenicity

Wed, 08 Mar 2017 15:03:38 GMT2017-03-08T15:03:38Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01159
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A Near-Infrared, Wavelength-Shiftable, Turn-on Fluorescent Probe for the Detection and Imaging of Cancer Tumor Cells

Tue, 07 Mar 2017 13:30:14 GMT2017-03-07T13:30:14Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01094
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Ion Mobility-Mass Spectrometry Reveals a Dipeptide That Acts as a Molecular Chaperone for Amyloid β

Mon, 06 Mar 2017 15:47:49 GMT2017-03-06T15:47:49Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00045
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The Role of the Secondary Coordination Sphere in a Fungal Polysaccharide Monooxygenase

Fri, 03 Mar 2017 18:23:29 GMT2017-03-03T18:23:29Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00016
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Lysine-Tryptophan-Crosslinked Peptides Produced by Radical SAM Enzymes in Pathogenic Streptococci

Fri, 03 Mar 2017 12:59:26 GMT2017-03-03T12:59:26Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01069
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NMR and Molecular Recognition of N-Glycans: Remote Modifications of the Saccharide Chain Modulate Binding Features

Fri, 03 Mar 2017 11:14:30 GMT2017-03-03T11:14:30Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01116
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Mitochondrial Cysteine Desulfurase and ISD11 Coexpressed in Escherichia coli Yield Complex Containing Acyl Carrier Protein

Thu, 02 Mar 2017 14:27:24 GMT2017-03-02T14:27:24Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01005
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Fluorescent Hexose Conjugates Establish Stringent Stereochemical Requirement by GLUT5 for Recognition and Transport of Monosaccharides

Thu, 02 Mar 2017 12:17:13 GMT2017-03-02T12:17:13Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01101
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Discovery and Characterization of a Potent and Specific Peptide Ligand Targeting Endothelial Progenitor Cells and Endothelial Cells for Tissue Regeneration

Thu, 02 Mar 2017 11:34:56 GMT2017-03-02T11:34:56Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00118
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The GCaMP-R Family of Genetically Encoded Ratiometric Calcium Indicators

Wed, 01 Mar 2017 18:41:05 GMT2017-03-01T18:41:05Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00883
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Argininosuccinate Synthase 1 is a Metabolic Regulator of Colorectal Cancer Pathogenicity

Wed, 01 Mar 2017 14:26:02 GMT2017-03-01T14:26:02Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01158
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A Fluorescent Hsp90 Probe Demonstrates the Unique Association between Extracellular Hsp90 and Malignancy in Vivo

Thu, 23 Feb 2017 04:05:30 GMT2017-02-23T04:05:30Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00006
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Iron Release from the Siderophore Pyoverdine in Pseudomonas aeruginosa Involves Three New Actors: FpvC, FpvG, and FpvH

Thu, 23 Feb 2017 14:24:11 GMT2017-02-23T14:24:11Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01077
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Highly Potent Cell-Permeable and Impermeable NanoLuc Luciferase Inhibitors

Wed, 22 Feb 2017 20:09:47 GMT2017-02-22T20:09:47Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01129
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O-GlcNAcylation of α-Synuclein at Serine 87 Reduces Aggregation without Affecting Membrane Binding

Wed, 22 Feb 2017 20:08:47 GMT2017-02-22T20:08:47Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00113
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Eg5 Inhibitors Have Contrasting Effects on Microtubule Stability and Metaphase Spindle Integrity

Wed, 22 Feb 2017 04:54:49 GMT2017-02-22T04:54:49Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01040
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Mechanistic Debris Generated by Twister Ribozymes

Tue, 21 Feb 2017 19:01:52 GMT2017-02-21T19:01:52Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00010
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The Activity of JmjC Histone Lysine Demethylase KDM4A is Highly Sensitive to Oxygen Concentrations

Mon, 20 Feb 2017 15:50:58 GMT2017-02-20T15:50:58Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00958
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Evolution and Distribution of C7–Cyclitol Synthases in Prokaryotes and Eukaryotes

Fri, 17 Feb 2017 18:19:16 GMT2017-02-17T18:19:16Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00066
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Control of an Unusual Photo-Claisen Rearrangement in Coumarin Caged Tamoxifen through an Extended Spacer

Fri, 17 Feb 2017 15:25:12 GMT2017-02-17T15:25:12Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00999
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Determinants of BH3 Sequence Specificity for the Disruption of Bcl-xL/cBid Complexes in Membranes

Fri, 17 Feb 2017 15:24:34 GMT2017-02-17T15:24:34Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01084
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Modification of the Orthosteric PPARγ Covalent Antagonist Scaffold Yields an Improved Dual-Site Allosteric Inhibitor

Thu, 16 Feb 2017 18:04:11 GMT2017-02-16T18:04:11Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01015
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Characterization of CYP115 As a Gibberellin 3-Oxidase Indicates That Certain Rhizobia Can Produce Bioactive Gibberellin A4

Thu, 16 Feb 2017 18:03:10 GMT2017-02-16T18:03:10Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01038
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The SUV39H1 Protein Lysine Methyltransferase Methylates Chromatin Proteins Involved in Heterochromatin Formation and VDJ Recombination

Thu, 16 Feb 2017 13:28:29 GMT2017-02-16T13:28:29Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01076
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Identifying Functional Cysteine Residues in the Mitochondria

Wed, 15 Feb 2017 18:43:33 GMT2017-02-15T18:43:33Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01074
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Chemoproteomic Screening of Covalent Ligands Reveals UBA5 As a Novel Pancreatic Cancer Target

Wed, 15 Feb 2017 18:41:23 GMT2017-02-15T18:41:23Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00020
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Structural and Epimeric Isomers of HPPH [3-Devinyl 3-{1-(1-hexyloxy) ethyl}pyropheophorbide-a]: Effects on Uptake and Photodynamic Therapy of Cancer

Wed, 15 Feb 2017 18:21:44 GMT2017-02-15T18:21:44Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00023
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Chemically-Modified Peptides Targeting the PDZ Domain of GIPC as a Therapeutic Approach for Cancer

Tue, 10 Mar 2015 04:40:22 GMT2015-03-10T04:40:22Z

ACS Chemical Biology
DOI: 10.1021/cb500865a
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