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ACS Chemical Biology: Latest Articles (ACS Publications)



latest articles published in ACS Chemical Biology



Copyright: Copyright 2017 American Chemical Society
 



Extensive Turnover of Compatible Solutes in Cyanobacteria Revealed by Deuterium Oxide (D2O) Stable Isotope Probing

Wed, 18 Jan 2017 20:18:23 GMT2017-01-18T20:18:23Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00890
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Fluorescent Branched RNAs for High-Throughput Analysis of Dbr1 Enzyme Kinetics and Inhibition

Wed, 18 Jan 2017 05:37:18 GMT2017-01-18T05:37:18Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00971
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Hepta-Mutant Staphylococcus aureus Sortase A (SrtA7m) as a Tool for in Vivo Protein Labeling in Caenorhabditis elegans

Wed, 18 Jan 2017 05:36:19 GMT2017-01-18T05:36:19Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00998
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Arylsulfatase K is the Lysosomal 2-Sulfoglucuronate Sulfatase

Tue, 17 Jan 2017 05:15:11 GMT2017-01-17T05:15:11Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01033
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Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis

Fri, 13 Jan 2017 19:43:35 GMT2017-01-13T19:43:35Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01031
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Inactivation of the Nuclear Orphan Receptor COUP-TFII by Small Chemicals

Fri, 13 Jan 2017 18:26:37 GMT2017-01-13T18:26:37Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00593
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An Allosteric Inhibitor Scaffold Targeting the PIF-Pocket of Atypical Protein Kinase C Isoforms

Fri, 13 Jan 2017 18:26:00 GMT2017-01-13T18:26:00Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00827
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Development of an Azoreductase-based Reporter System with Synthetic Fluorogenic Substrates

Fri, 13 Jan 2017 14:53:01 GMT2017-01-13T14:53:01Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00852
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Structural and Functional Basis of C-Methylation of Coumarin Scaffolds by NovO

Fri, 13 Jan 2017 14:06:48 GMT2017-01-13T14:06:48Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01053
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A Highly Promiscuous ß-Ketoacyl-ACP Synthase (KAS) III-like Protein Is Involved in Pactamycin Biosynthesis

Thu, 12 Jan 2017 18:56:13 GMT2017-01-12T18:56:13Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01043
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Chemical Modifications to RNA: A New Layer of Gene Expression Regulation

Thu, 12 Jan 2017 18:23:51 GMT2017-01-12T18:23:51Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00960
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Development of Autologous C5 Vaccine Nanoparticles to Reduce Intravascular Hemolysis in Vivo

Thu, 12 Jan 2017 18:23:00 GMT2017-01-12T18:23:00Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00994
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Global N-Glycan Site Occupancy of HIV-1 gp120 by Metabolic Engineering and High-Resolution Intact Mass Spectrometry

Mon, 09 Jan 2017 19:12:01 GMT2017-01-09T19:12:01Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00854
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N@a and N@d: Oligomer and Partner Specification by Asparagine in Coiled-Coil Interfaces

Mon, 09 Jan 2017 14:52:17 GMT2017-01-09T14:52:17Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00935
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Iterative Focused Screening with Biological Fingerprints Identifies Selective Asc-1 Inhibitors Distinct from Traditional High Throughput Screening

Fri, 06 Jan 2017 16:59:21 GMT2017-01-06T16:59:21Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00913
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Duration Control of Protein Expression in Vivo by Light-Mediated Reversible Activation of Translation

Wed, 04 Jan 2017 06:00:07 GMT2017-01-04T06:00:07Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00684
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Profiling Protease Specificity: Combining Yeast ER Sequestration Screening (YESS) with Next Generation Sequencing

Tue, 03 Jan 2017 18:05:49 GMT2017-01-03T18:05:49Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00547
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Translocation of an Intracellular Protein via Peptide-Directed Ligation

Tue, 03 Jan 2017 05:11:45 GMT2017-01-03T05:11:45Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01013
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A Photoactivatable Innate Immune Receptor for Optogenetic Inflammation

Thu, 29 Dec 2016 19:39:43 GMT2016-12-29T19:39:43Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01012
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Exploring the Structural Compliancy versus Specificity of the Estrogen Receptor Using Isomeric Three-Dimensional Ligands

Thu, 29 Dec 2016 19:14:00 GMT2016-12-29T19:14:00Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00918
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Kinetic Isotope Effects and Transition State Structure for Human Phenylethanolamine N-Methyltransferase

Wed, 28 Dec 2016 18:31:43 GMT2016-12-28T18:31:43Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00922
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Trapping Reactions of the Sulfenyl and Sulfinyl Tautomers of Sulfenic Acids

Wed, 28 Dec 2016 18:30:43 GMT2016-12-28T18:30:43Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00980
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Characterization of Two Late-Stage Enzymes Involved in Fosfomycin Biosynthesis in Pseudomonads

Tue, 27 Dec 2016 14:31:33 GMT2016-12-27T14:31:33Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00939
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hBfl-1/hNOXA Interaction Studies Provide New Insights on the Role of Bfl-1 in Cancer Cell Resistance and for the Design of Novel Anticancer Agents

Tue, 27 Dec 2016 14:18:29 GMT2016-12-27T14:18:29Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00962
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Heat Capacity Changes for Transition-State Analogue Binding and Catalysis with Human 5′-Methylthioadenosine Phosphorylase

Tue, 27 Dec 2016 14:06:52 GMT2016-12-27T14:06:52Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00885
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Rapid Chagas Disease Drug Target Discovery Using Directed Evolution in Drug-Sensitive Yeast

Fri, 23 Dec 2016 18:35:07 GMT2016-12-23T18:35:07Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01037
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Discovery of Inhibitors of MicroRNA-21 Processing Using Small Molecule Microarrays

Fri, 23 Dec 2016 05:46:34 GMT2016-12-23T05:46:34Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00945
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The GLO1 Gene Is Required for Full Activity of O-Acetyl Homoserine Sulfhydrylase Encoded by MET17

Thu, 22 Dec 2016 21:22:21 GMT2016-12-22T21:22:21Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00815
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A Rationally Designed, General Strategy for Membrane Orientation of Photoinduced Electron Transfer-Based Voltage-Sensitive Dyes

Thu, 22 Dec 2016 14:42:13 GMT2016-12-22T14:42:13Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00981
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Proteoform-Specific Protein Binding of Small Molecules in Complex Matrices

Wed, 21 Dec 2016 21:23:24 GMT2016-12-21T21:23:24Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01018
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Mechanism of the Spontaneous and Directional Membrane Insertion of a 2-Transmembrane Ion Channel

Wed, 21 Dec 2016 18:12:10 GMT2016-12-21T18:12:10Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01085
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Heparin-Promoted Cellular Uptake of the Cell-Penetrating Glycosaminoglycan Binding Peptide, GBPECP, Depends on a Single Tryptophan

Wed, 21 Dec 2016 15:59:27 GMT2016-12-21T15:59:27Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00864
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SIRT7 Is an RNA-Activated Protein Lysine Deacylase

Tue, 20 Dec 2016 20:20:49 GMT2016-12-20T20:20:49Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00954
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Engineering High Affinity Protein–Protein Interactions Using a High-Throughput Microcapillary Array Platform

Tue, 20 Dec 2016 20:20:19 GMT2016-12-20T20:20:19Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00794
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Engineering Cyclohexanone Monooxygenase for the Production of Methyl Propanoate

Tue, 20 Dec 2016 15:10:51 GMT2016-12-20T15:10:51Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00965
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Internal Structure and Preferential Protein Binding of Colloidal Aggregates

Fri, 16 Dec 2016 05:52:10 GMT2016-12-16T05:52:10Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00791
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A Look into the Biochemistry of Magnetosome Biosynthesis in Magnetotactic Bacteria

Fri, 16 Dec 2016 05:12:50 GMT2016-12-16T05:12:50Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b01000
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Lipidomics Characterization of Biosynthetic and Remodeling Pathways of Cardiolipins in Genetically and Nutritionally Manipulated Yeast Cells

Fri, 16 Dec 2016 16:58:50 GMT2016-12-16T16:58:50Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00995
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LSD1 Substrate Binding and Gene Expression Are Affected by HDAC1-Mediated Deacetylation

Thu, 15 Dec 2016 21:20:54 GMT2016-12-15T21:20:54Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00776
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Elucidating the Origin of Long Residence Time Binding for Inhibitors of the Metalloprotease Thermolysin

Tue, 13 Dec 2016 19:18:15 GMT2016-12-13T19:18:15Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00979
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Transformation of the Non-Selective Aminocyclohexanol-Based Hsp90 Inhibitor into a Grp94-Seletive Scaffold

Tue, 13 Dec 2016 05:50:34 GMT2016-12-13T05:50:34Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00747
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High-throughput Identification of DNA-Encoded IgG Ligands that Distinguish Active and Latent Mycobacterium tuberculosis Infections

Tue, 13 Dec 2016 12:20:05 GMT2016-12-13T12:20:05Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00855
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A Chemical Biology Solution to Problems with Studying Biologically Important but Unstable 9-O-Acetyl Sialic Acids

Mon, 12 Dec 2016 05:16:18 GMT2016-12-12T05:16:18Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00928
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Probing the Binding Interfaces of Histone-Aptamer by Photo Cross-Linking Mass Spectrometry

Mon, 12 Dec 2016 05:16:17 GMT2016-12-12T05:16:17Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00797
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Cell-Density Dependence of Host-Defense Peptide Activity and Selectivity in the Presence of Host Cells

Fri, 09 Dec 2016 19:51:31 GMT2016-12-09T19:51:31Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00910
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Catalytic Promiscuity of O-GlcNAc Transferase Enables Unexpected Metabolic Engineering of Cytoplasmic Proteins with 2-Azido-2-deoxy-glucose

Fri, 09 Dec 2016 16:16:27 GMT2016-12-09T16:16:27Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00876
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Histone Ketoamide Adduction by 4-Oxo-2-nonenal Is a Reversible Posttranslational Modification Regulated by Sirt2

Wed, 07 Dec 2016 19:14:33 GMT2016-12-07T19:14:33Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00713
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Live Cell Imaging of Endogenous mRNA Using RNA-Based Fluorescence “Turn-On” Probe

Wed, 07 Dec 2016 05:27:33 GMT2016-12-07T05:27:33Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00586
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Assigning the Algal Source of Dimethylsulfide Using a Selective Lyase Inhibitor

Tue, 06 Dec 2016 16:06:57 GMT2016-12-06T16:06:57Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00844
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What Can We Learn from Bioactivity Data? Chemoinformatics Tools and Applications in Chemical Biology Research

Mon, 05 Dec 2016 21:33:05 GMT2016-12-05T21:33:05Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00706
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Disruption of Mycobacterial AftB Results in Complete Loss of Terminal β(1 → 2) Arabinofuranose Residues of Lipoarabinomannan

Mon, 05 Dec 2016 15:33:29 GMT2016-12-05T15:33:29Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00898
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Observing Biosynthetic Activity Utilizing Next Generation Sequencing and the DNA Linked Enzyme Coupled Assay

Mon, 05 Dec 2016 15:15:28 GMT2016-12-05T15:15:28Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00652
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Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis

Fri, 02 Dec 2016 16:42:47 GMT2016-12-02T16:42:47Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00849
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Sudemycin K: A Synthetic Antitumor Splicing Inhibitor Variant with Improved Activity and Versatile Chemistry

Thu, 01 Dec 2016 05:34:11 GMT2016-12-01T05:34:11Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00562
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Mapping the Phosphorylation Pattern of Drosophila melanogaster RNA Polymerase II Carboxyl-Terminal Domain Using Ultraviolet Photodissociation Mass Spectrometry

Thu, 01 Dec 2016 16:54:17 GMT2016-12-01T16:54:17Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00729
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Structure and Function of a C–C Bond Cleaving Oxygenase in Atypical Angucycline Biosynthesis

Wed, 30 Nov 2016 05:53:51 GMT2016-11-30T05:53:51Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00621
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Phenotypic Screen for Cardiac Regeneration Identifies Molecules with Differential Activity in Human Epicardium-Derived Cells versus Cardiac Fibroblasts

Wed, 30 Nov 2016 15:03:43 GMT2016-11-30T15:03:43Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00683
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Genome Mining of Amino Group Carrier Protein-Mediated Machinery: Discovery and Biosynthetic Characterization of a Natural Product with Unique Hydrazone Unit

Wed, 30 Nov 2016 13:47:44 GMT2016-11-30T13:47:44Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00818
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Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering

Tue, 29 Nov 2016 05:47:47 GMT2016-11-29T05:47:47Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00732
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An Advance in Prescription Opioid Vaccines: Overdose Mortality Reduction and Extraordinary Alteration of Drug Half-Life

Tue, 29 Nov 2016 16:39:51 GMT2016-11-29T16:39:51Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00977
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Complete Tetrasaccharide Repeat Unit Biosynthesis of the Immunomodulatory Bacteroides fragilis Capsular Polysaccharide A

Mon, 28 Nov 2016 15:58:55 GMT2016-11-28T15:58:55Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00931
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Targeting NF-κB p65 with a Helenalin Inspired Bis-electrophile

Mon, 28 Nov 2016 15:58:21 GMT2016-11-28T15:58:21Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00751
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Structure Based Substrate Specificity Analysis of Heparan Sulfate 6-O-Sulfotransferases

Tue, 22 Nov 2016 19:49:21 GMT2016-11-22T19:49:21Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00841
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Activation Pathway of a Nucleoside Analog Inhibiting Respiratory Syncytial Virus Polymerase

Tue, 22 Nov 2016 12:35:39 GMT2016-11-22T12:35:39Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00788
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An Effective Bacterial Fucosidase for Glycoprotein Remodeling

Fri, 18 Nov 2016 18:52:47 GMT2016-11-18T18:52:47Z

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ACS Chemical Biology
DOI: 10.1021/acschembio.6b00821
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Chemically-Modified Peptides Targeting the PDZ Domain of GIPC as a Therapeutic Approach for Cancer

Tue, 10 Mar 2015 05:40:22 GMT2015-03-10T05:40:22Z

ACS Chemical Biology
DOI: 10.1021/cb500865a
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