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PENN Medicine Orthopaedics News



The latest news from the University of Pennsylvania School of Medicine and Health System.



Copyright: 2008, The Trustees of the University of Pennsylvania
 



Altering Stem Cell Perception of Tissue Stiffness May Help Treat Musculoskeletal Disorders, According to Penn Bioengineering Study

Thu, 25 Aug 2016 15:30:00 GMT

A new biomaterial can be used to study how and when stem cells sense the mechanics of their surrounding environment, found a team led by Robert Mauck, PhD, the Mary Black Ralston Professor for Education and Research in Orthopaedic Surgery, in the Perelman School of Medicine at the University of Pennsylvania.



Quieting Cells' Low-Oxygen Alarm Stops Flare-ups in Rare Bone Disorder, Penn Animal Study Finds

Mon, 02 May 2016 15:00:00 GMT

Scientists from the Center for Research in FOP and Related Disorders at the Perelman School of Medicine at the University of Pennsylvania and colleagues examined the critical role of tissue hypoxia, or oxygen starvation, in the induction and amplification of FOP lesions, also called flare-ups.



Drug Candidate Stops Extra Bone Growth in Animal Model of Rare, Genetic Disease

Wed, 13 Apr 2016 14:45:00 GMT

New preclinical research provides support to a drug that has been repurposed to possibly treat a rare and extremely disabling genetic bone disease, particularly in children. In that disease, fibrodysplasia ossificans progressiva (FOP), a mutation triggers bone growth in muscles, alters skeletal bone formation, and limits motion, breathing, and swallowing, among a host of progressive symptoms.



New Understanding of Knee Fibrocartilage Structure Could Aid in Development of Better Replacements and Injury Treatments

Fri, 08 Jan 2016 13:30:00 GMT

Fibrocartilage tissue in the knee is comprised of a more varied molecular structure than researchers previously appreciated, according to a new study by researchers from the Perelman School of Medicine at the University of Pennsylvania and the University of Delaware.



Penn-Sponsored Million Dollar Bike Ride to Raise Awareness about Rare Diseases

Tue, 28 Apr 2015 16:00:00 GMT

The second annual Million Dollar Bike Ride will be held on Saturday, May 9, 2015, to support research and raise awareness about rare diseases.



Malnourished Patients are More Likely to Suffer Postoperative Complications than Morbidly Obese Patients Following Knee, Hip Replacement, Penn Study Finds

Fri, 27 Mar 2015 15:00:00 GMT

Malnourished patients are more likely to have complications following total knee or hip replacement surgeries than morbidly obese patients,according to new research from researchers at the Perelman School of Medicine at the University of Pennsylvania.



Most NFL Players with Injuries to the Midfoot Return to Game Action, Penn Medicine Study Finds

Fri, 27 Mar 2015 04:01:00 GMT

Nearly 93 percent of National Football League (NFL) athletes who sustained traumatic injuries to the midfoot returned to competition less than 15 months after injury and with no statistically significant decrease in performance, according to new research from the Perelman School of Medicine at the University of Pennsylvania.



Penn Medicine Experts Unveil Two New Ways to Identify Joint Replacement Patients at Risk for Post-Operative Complications

Thu, 26 Mar 2015 00:01:00 GMT

Orthopedic surgeons from the Perelman School of Medicine at the University of Pennsylvania have developed two new prediction tools aimed at identifying total hip and knee replacement patients who are at-risk of developing serious complications after surgery.



Penn Medicine Study: In Debated Surgical Procedure, Technique Trumps Technology

Thu, 26 Mar 2015 00:01:00 GMT

A team of orthopedic surgeons from the Perelman School of Medicine at the University of Pennsylvania has found that modern technology for healing distal femur fractures is as safe and effective as its more established alternative, without a potential shortfall of the older approach.



Penn Scientist Given Prestigious Award for Young Orthopaedic Researchers

Thu, 26 Mar 2015 00:01:00 GMT

Robert L. Mauck, PhD, an associate professor of Orthopaedic Surgery at the Perelman School of Medicine at the University of Pennsylvania, is one of four scientists given awards by the Kappa Delta Sorority and the Orthopaedic Research and Education Foundation at the 2015 Annual Meeting of the American Academy of Orthopaedic Surgeons in Las Vegas.



Media Toolkit: Penn Medicine at the American Academy of Orthopaedic Surgeons 2015 Annual Meeting

Wed, 25 Mar 2015 16:00:00 GMT

Experts from the Perelman School of Medicine at the University of Pennsylvania will be moderating panels, serving as discussants and presenting research findings on the latest advances in orthopaedic surgery, research and education at the 2015 American Academy of Orthopaedic Surgerons Annual Meeting in Las Vegas, March 24-28, 2015.



Penn Study Finds Smoking Prolongs Fracture Healing and Increases Risk of Infection

Fri, 22 March 2012 14:30:00 GMT

Research has long shown the negative effects cigarette smoking has on cardiovascular health. But now, a new study from the Department of Orthopaedic Surgery at the Perelman School of Medicine at the University of Pennsylvania corroborates early evidence showing that cigarette smoking leads to longer healing times and an increased rate of post-operative complication and infection for patients sustaining fractures or traumatic injuries to their bone. The full results of the study are being presented this week at the 2013 American Academy of Orthopaedic Surgeons annual meeting in Chicago.



Pre-Op Triage of Total Hip Replacement Patients Improves Outcomes

Fri, 22 March 2012 14:30:00 GMT

According to a new study by researchers from the Perelman School of Medicine at the University of Pennsylvania, pre-operatively identifying patients with certain comorbid risk factors that may increase their chance of being admitted to the ICU following total hip replacement surgery results in fewer deaths, post-surgery complications, and unplanned ICU admissions. The full results of the study will be presented at the 2013 American Academy of Orthopaedic Surgeons Annual Meeting this week in Chicago.



Penn Study Questions Efficacy and Unintentional Affects of Patient/Physician Shared Decision-Making

Fri, 22 March 2012 14:30:00 GMT

Shared decision-making between patients and physicians about health care decisions has previously been presented as superior to an approach that emphasizes physicians taking a leading role in directing key aspects of a patient's care. But now, a new study by researchers from the Perelman School of Medicine at the University of Pennsylvania, calls into question the efficacy of shared decision-making as a tool for eliciting a patient's genuine preference for care. The results of the study will be presented this week at the 2013 American Academy of Orthopaedic Surgeons Annual Meeting in Chicago.



Differences in Bone Healing in Young Vs. Old Mice May Hold Answers to Better Bone Healing for Seniors

Wed, 20 March 2012 14:00:00 GMT

By studying the underlying differences in gene expression during healing after a bone break in young versus aged mice, Jaimo Ahn, MD, PhD, assistant professor of Orthopaedic Surgery at the Perelman School of Medicine, University of Pennsylvania, and his colleagues aim to find specific pathways of fracture healing in humans.



Penn Orthopaedics at Penn Presbyterian Medical Center Receives Gold Seal of Approval from The Joint Commission

Tue, 14 August 2012 13:00:00 GMT

Penn Presbyterian Medical Center (PPMC) has earned the Gold Seal of Approval from The Joint Commission for its hip and knee joint replacement services.



Misplaced Metamorphosis: Penn Researchers Identify Source of Cells that Spur Aberrant Bone Growth

Tue, 03 March 2009 17:30:00 GMT

Researchers at the University of Pennsylvania School of Medicine and the University of Connecticut have pinpointed the source of immature cells that spur misplaced bone growth. Unexpectedly, the major repository of bone-forming cells originates in blood vessels deep within skeletal muscle and other connective tissues, not from muscle stem cells themselves. The work also shows that cells important in the inflammatory response to injury trigger skeleton-stimulating proteins to transform muscle tissue into bone.



Penn Medicine Appoints L. Scott Levin, MD, FACS, Chair of Orthopaedic Surgery

Tue, 19 May 2009 15:30:00 GMT

L. Scott Levin, MD, FACS, has been appointed the new Chair of the Department of Orthopaedic Surgery of Penn Medicine, effective July 1, 2009.



Acid Suppression Medication Linked With Increased Risk of Hip Fracture
Use of proton pump inhibitor (PPI) drugs for the treatment of acid-related diseases such as gastroesophageal reflux disease (GERD) is associated with a greater risk of hip fracture, according to a study in the December 27 issue of the Journal of the American Medical Association.



Targeting a Single Gene Could Inhibit Bone Decay and Stimulate Bone Growth
Researchers at the University of Pennsylvania School of Medicine have found by targeting the function of a single gene that it is possible to inhibit bone decay while simultaneously stimulating bone formation. This concept may lead to drug treatments for osteoporosis and other bone diseases. Senior author Yongwon Choi, PhD, professor of Pathology and Laboratory Medicine at the University of Pennsylvania and colleagues report their findings in the December issue of Nature Medicine.



Penn Orthopaedic Surgeon Wins First Annual Health Breakthrough Award
Mary Ann Keenan, MD, Chief of Neuro-Orthopaedics for the University of Pennsylvania Health System, has been named a recipient of the first-annual Ladies' Home Journal Health Breakthrough Awards. The award recognizes leading medical professionals who are making life-saving and life-enhancing discoveries in research, treatment and diagnostics that have significantly helped women and families.