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Last Build Date: Sat, 24 Jun 2017 08:56:22 GMT

 



Evolution

Sat, 24 Jun 2017 08:00:51 GMT

Names

← Older revision Revision as of 08:00, 24 June 2017
Line 2: Line 2:
{{KeyPointsBox|Evolutionary biology helps understanding of much human disease from the modern epidemics of obesity and diabetes to [[malaria]] and [[influenza]] and has practical application in modern therapy and interventions such as restricted antibiotic formularies.}}
{{KeyPointsBox|Evolutionary biology helps understanding of much human disease from the modern epidemics of obesity and diabetes to [[malaria]] and [[influenza]] and has practical application in modern therapy and interventions such as restricted antibiotic formularies.}}
-
See [[Wikipedia:Evolution]] for basic understanding which is assumed in this Wiki for a theory first announced formally in [[1858]]. This understanding simplifies the interpretation of the contents of this wiki and application of that knowledge.  
+
See [[Wikipedia:Evolution]] for basic understanding which is assumed in this Wiki for a theory first announced formally in [[1858]] based on the research of Alfred Russel Wallace and Charles Darwin. This understanding simplifies the interpretation of the contents of this wiki and application of that knowledge.  
A critical modern concept is that the genetic material of individual species does not just evolve through horizontal transmission through the species but also there has been critically evolutionarily interchange between species. Thus the genome of the bacterium [[Wolbachia]] is found almost intact in some filarial nematodes and humans incorporate genes from viruses associated with human disease. This concept results in what has been termed the Darwinian rhizome as a better model for evolutionary relationships than the faulty Darwinian tree of the text books.   
A critical modern concept is that the genetic material of individual species does not just evolve through horizontal transmission through the species but also there has been critically evolutionarily interchange between species. Thus the genome of the bacterium [[Wolbachia]] is found almost intact in some filarial nematodes and humans incorporate genes from viruses associated with human disease. This concept results in what has been termed the Darwinian rhizome as a better model for evolutionary relationships than the faulty Darwinian tree of the text books.   



Adrenomedullin

Fri, 23 Jun 2017 22:59:06 GMT

← Older revision Revision as of 22:59, 23 June 2017
(One intermediate revision not shown)
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{{BiochemistryBox||ADM, AM, ADM2, Intermedin-long,IMDL, Intermedin-short, IMDS}}
{{BiochemistryBox||ADM, AM, ADM2, Intermedin-long,IMDL, Intermedin-short, IMDS}}
-
adrenomedullin is a protein family of hormone signal peptides related to [[calcitonin]]. The adrenomedullin receptor protein complex shares components with the [[calcitonin gene-related peptide type 1]] receptor.
+
adrenomedullin is a protein family of hormone signal peptides related to [[calcitonin]]. The adrenomedullin receptor protein complex shares components with the [[calcitonin gene-related peptide type 1 receptor]].
==Adrenomedullin-1==
==Adrenomedullin-1==
-
Usually just termed '''adrenomedullin (AM, ADM)''' as it is in fairly high concentrations in the blood, it is a 52 aminoacid protein enzymatically formed from [[preproadrenomedullin]](ADM precursor) that acts as a :
+
Usually just termed '''adrenomedullin (AM, ADM)''' as it is in fairly high concentrations in the blood, it is a 52 amino acid protein enzymatically formed from [[preproadrenomedullin]](ADM precursor) that acts as a :
*[[Vasodilator]]
*[[Vasodilator]]
*[[Diuretic]]
*[[Diuretic]]



Stalking

Fri, 23 Jun 2017 13:00:09 GMT

← Older revision Revision as of 13:00, 23 June 2017 Line 1: Line 1: {{stub}}   {{stub}}   -Doctors may have patients who are (or believe themselves to be) victims if stalking. They may also be victims themselves.  +{{SubjectBox|}}  +{{QuotationBox|Stalking is a widespread phenomenon describing a pattern of intrusive and threatening behavior that leads to the victim's perception of being harassed, threatened and frightened. Physical assault and even homicide may sometimes occur in the context of stalking. For psychiatry the following tasks result: (1) diagnosis and classification of stalking cases, (2) risk assessment of stalking cases, (3) counselling and treatment of victims of stalking and, (4) treatment and assessment of stalkers.|Dressing[https://link.springer.com/article/10.1007%2Fs00115-013-3881-x Stalking: diagnostics, risk assessment, principles of treatment and forensic psychiatric assessment (original in German). Der Nervenarzt 2013;84(11):1385-94; quiz 1395-6  PMID: 24166016  doi: 10.1007/s00115-013-3881-x.]}}{{QuotationBox| …stalking is a widespread phenomenon… evidence suggests that serious violence and even homicide may occur in the context of stalking|Dressing, Kuehner & Gass.[https://insights.ovid.com/pubmed?pmid=16721170 Dressing H, Kuehner C, Gass P. The epidemiology and characteristics of stalking. Current opinion in psychiatry 2006;19(4):395-9  PMID: 16721170  doi: 10.1097/01.yco.0000228760.95237.f5]}}  +Doctors may have patients who are (or believe themselves to be) victims of stalking. They may also be victims themselves.   -Doctors' experiences of stalking range from inappropriate but harmless approaches approaches by patients through to a level of threat that makes it impossible to continue in practice.[https://www.google.co.uk/amp/s/amp.theguardian.com/society/2012/oct/28/lovesick-patients-stalk-doctors-online Denis Campbell. ''Infatuated patients use Facebook to stalk doctors''  +Doctors' experiences of stalking range from inappropriate but harmless approaches by patients through to a level of threat that makes it impossible to continue in practice.[https://www.google.co.uk/amp/s/amp.theguardian.com/society/2012/oct/28/lovesick-patients-stalk-doctors-online Denis Campbell. ''Infatuated patients use Facebook to stalk doctors'' 27 October 2012 Guardian][http://www.itv.com/news/west/2016-04-06/doctor-stalked-for-seven-years-backs-calls-for-longer-sentences/ Doctor stalked for seven years backs calls for longer sentences. ITV news 2016] -27 October 2012 Guardian][http://www.itv.com/news/west/2016-04-06/doctor-stalked-for-seven-years-backs-calls-for-longer-sentences/ Doctor stalked for seven years backs calls for longer sentences. ITV news 2016]+ Despite stalking being a criminal offence, there have been reports suggesting that police forces do not always take stalking seriously.    Despite stalking being a criminal offence, there have been reports suggesting that police forces do not always take stalking seriously.    [...]



Hepatitis B

Fri, 23 Jun 2017 10:54:07 GMT

Blood tests: ← Older revision Revision as of 10:54, 23 June 2017 Line 123: Line 123: ===Blood tests=== ===Blood tests=== There are a number of markers of hepatitis B infection, including the presence or absence of viral antigens, and [[Antibody|antibodies]] to these antigens, as well as markers of liver damage. The key antigens are the surface ('s'), core ('c') and 'e'-antigens (HBs, HBc, and HBe).   There are a number of markers of hepatitis B infection, including the presence or absence of viral antigens, and [[Antibody|antibodies]] to these antigens, as well as markers of liver damage. The key antigens are the surface ('s'), core ('c') and 'e'-antigens (HBs, HBc, and HBe).   -{{/Interpretation}}   +A consultation draft of a [[Standards for Microbiology Investigations|UK SMI (Standards for Microbiology Investigations]] was published on 12 June [[2017]].[https://www.gov.uk/government/consultations/uk-smi-v-4-investigation-of-hepatitis-b-infection-third-consultation Public Health England National Infection Service. ''UK Standards for Microbiology Investigations: Investigation of hepatitis B infection (consultation draft).'' London: National Infection Service, Public Health England, 2017 (June 12).] It provides a useful explanation of the tests and their interpretation. (Once published, the final draft is likely to be available via the [https://www.gov.uk/uk-standards-for-microbiology-investigations-smi-quality-and-consistency-in-clinical-laboratories UK SMI website]).  +  +{{/Interpretation}} ===Radiology=== ===Radiology=== [...]



Standards for Microbiology Investigations

Fri, 23 Jun 2017 10:03:49 GMT

New page

{{stub}}
[[Category: Microbiology]]
[[Category: Mycology]]
[[Category: Virology]]
[[Category: Parasitology]]

{{UK|UK SMIs}}
A suite of UK Standards for Microbiology Investigations (UK SMIs) is being developed.

According to the metadata information in one consultation draft SMI:[https://www.gov.uk/government/consultations/uk-smi-v-4-investigation-of-hepatitis-b-infection-third-consultation Public Health England National Infection Service. ''UK Standards for Microbiology Investigations: Investigation of hepatitis B infection (consultation draft).'' London: National Infection Service, Public Health England, 2017 (June 12).]
:"UK Standards for Microbiology Investigations (UK SMIs) are developed under the auspices of Public Health England (PHE) working in partnership with the National Health Service (NHS), Public Health Wales and with the professional organisations whose logos are displayed below and listed on the website https://www.gov.uk/uk-standards-for-microbiology-investigations-smi-quality-and-consistency-in-clinical-laboratories. UK SMIs are developed, reviewed and revised by various working groups which are overseen by a steering committee (see https://www.gov.uk/government/groups/standards-for-microbiology-investigations-steering-committee).
:"The contributions of many individuals in clinical, specialist and reference laboratories who have provided information and comments during the development of this document are acknowledged. We are grateful to the medical editors for editing the medical content.

"Website: [https://www.gov.uk/uk-standards-for-microbiology-investigations-smi-quality-and-consistency-in-clinical-laboratories https://www.gov.uk/uk-standards-for-microbiology-investigations-smi-quality-and-consistency-in-clinical-laboratories]"


NB - for this purposes of the UK SMIs:
:''"Microbiology is used as a generic term to include the two GMC-recognised specialties of Medical Microbiology (which includes Bacteriology, Mycology and Parasitology) and Medical Virology."''

{{Refsec}}



Abbreviations

Fri, 23 Jun 2017 09:55:33 GMT

S:

← Older revision Revision as of 09:55, 23 June 2017
Line 722: Line 722:
*SMA - superior mesenteric artery
*SMA - superior mesenteric artery
*SMC - [[Scottish Medicines Consortium]]. The Scottish equivalent of [[NICE]]
*SMC - [[Scottish Medicines Consortium]]. The Scottish equivalent of [[NICE]]
 +
*SMI - [[Standards for Microbiology Investigations]]
*SLS - Selected List Scheme (used in [[BNF]])
*SLS - Selected List Scheme (used in [[BNF]])
*SLUNGS - Self Limited Unusual No Great Significance (Many conditions seen in primary care are SLUNGS. Abbreviation invented by a [https://www.doctors.net.uk/Forum/viewPost.aspx?post_id=4645525&forum_id=11 DNUKer].)  
*SLUNGS - Self Limited Unusual No Great Significance (Many conditions seen in primary care are SLUNGS. Abbreviation invented by a [https://www.doctors.net.uk/Forum/viewPost.aspx?post_id=4645525&forum_id=11 DNUKer].)  



Category:EZH2 inhibitors

Fri, 23 Jun 2017 07:44:48 GMT

categorise

New page

[[Category:drug classes]]
Inhibitors of [[histone methyltransferase EZH2]] acting upon regulation of [[chromatin]] structure and [[gene]] expression.



Tazemetostat

Fri, 23 Jun 2017 07:43:07 GMT

new class of drugs

New page

{{PharmacologyBox||EPZ-6438}}
Tazemetostat is a [[EZH2]] inhibitor being developed for treatment of soft tissue [[sarcoma]]s, [[mesothelioma]] and [[lymphoma]]s (such as [[diffuse large B-cell lymphoma]], DLBCL). EZH2-activating mutations are important in such tumours as post-translational modification of [[:Category:histones|histones]] is critical for regulation of [[chromatin]] structure and gene expression. [[EZH2]] codes for the catalytic subunit of the [[polycomb repressive complex 2]] (PRC2), also known as [[histone methyltransferase EZH2]].
[[Category:EZH2 inhibitors]]
[[Category:Unlicensed medicines]]



Idebenone

Fri, 23 Jun 2017 07:32:41 GMT

tradename ← Older revision Revision as of 07:32, 23 June 2017 Line 1: Line 1: -{{PharmacologyBox||SNT-MC17|[[image:{{PAGENAME}}Molecule.png|thumb|{{PAGENAME}} Molecule]]|[[image:{{PAGENAME}}.png|center]]||synthetic analogue of [[Coenzyme Q10]]|}}+{{PharmacologyBox||SNT-MC17, Raxone|[[image:{{PAGENAME}}Molecule.png|thumb|{{PAGENAME}} Molecule]]|[[image:{{PAGENAME}}.png|center]]||synthetic analogue of [[Coenzyme Q10]]|}} Orphan drug in development. Appears to improve energy production within nerve and muscle cells in patients with [[Friedreich's ataxia]] and [[Duchenne muscular dystrophy]][http://www.ncbi.nlm.nih.gov/sites/entrez?itool=abstractplus&db=pubmed&cmd=Retrieve&dopt=abstractplus&list_uids=25907158  Buyse GM, Voit T, Schara U, Straathof CS, D'Angelo MG, Bernert G, Cuisset JM, Finkel RS, Goemans N, McDonald CM, Rummey C, Meier T. Efficacy of idebenone on respiratory function in patients with Duchenne muscular dystrophy not using glucocorticoids (DELOS): a double-blind randomised placebo-controlled phase 3 trial. Lancet. 2015 Apr 20.](Epub ahead of print) ([http://dx.doi.org/10.1016/S0140-6736(15)60025-3 Link to article] – subscription may be required.), protecting these cells from cell death. Orphan drug in development. Appears to improve energy production within nerve and muscle cells in patients with [[Friedreich's ataxia]] and [[Duchenne muscular dystrophy]][http://www.ncbi.nlm.nih.gov/sites/entrez?itool=abstractplus&db=pubmed&cmd=Retrieve&dopt=abstractplus&list_uids=25907158  Buyse GM, Voit T, Schara U, Straathof CS, D'Angelo MG, Bernert G, Cuisset JM, Finkel RS, Goemans N, McDonald CM, Rummey C, Meier T. Efficacy of idebenone on respiratory function in patients with Duchenne muscular dystrophy not using glucocorticoids (DELOS): a double-blind randomised placebo-controlled phase 3 trial. Lancet. 2015 Apr 20.](Epub ahead of print) ([http://dx.doi.org/10.1016/S0140-6736(15)60025-3 Link to article] – subscription may be required.), protecting these cells from cell death. It is a CoQ10 analogue and is being tried in a wide range of mitochondrial metabolic conditions such as [[Mitochondrial diseases|Leber's hereditary optic neuropathy]] and hepatic injury . [[Category:Ubiquinones]][[Category:Medicines]] It is a CoQ10 analogue and is being tried in a wide range of mitochondrial metabolic conditions such as [[Mitochondrial diseases|Leber's hereditary optic neuropathy]] and hepatic injury . [[Category:Ubiquinones]][[Category:Medicines]] [[Category:Orphan drugs]] [[Category:Orphan drugs]] {{refsec}} {{refsec}} [...]



RAMP2

Fri, 23 Jun 2017 07:27:59 GMT

subclude

New page

{{GeneticsBox}}
[[Category:Genes]]
{{:Receptor activity-modifying protein 2}}



RAMP3

Fri, 23 Jun 2017 07:27:43 GMT

subclude

New page

{{GeneticsBox}}
[[Category:Genes]]
{{:Receptor activity-modifying protein 3}}



Receptor activity-modifying protein 3

Fri, 23 Jun 2017 07:27:07 GMT

for subclusion

New page


{{BiochemistryBox|||Calcitonin-receptor-like receptor activity-modifying protein 3, CRLR activity-modifying protein 3}}
[[Category:Transport proteins]]
[[Category:Transporter proteins]]
[[Category:Receptor proteins]]

The [[RAMP3]] gene at 7p13 codes for the 148 amino acid [[receptor activity-modifying protein 3]]. This allows the transport of the [[calcitonin gene-related peptide type 1 receptor]] to the plasma membrane where the complex acts as a receptor for [[adrenomedullin]].



Receptor activity-modifying protein 2

Fri, 23 Jun 2017 07:26:58 GMT

for subclusion

New page


{{BiochemistryBox|||Calcitonin-receptor-like receptor activity-modifying protein 2, CRLR activity-modifying protein 2}}
[[Category:Transport proteins]]
[[Category:Transporter proteins]]
[[Category:Receptor proteins]]

The [[RAMP2]] gene at 17q21.31 codes for the 175 amino acid [[receptor activity-modifying protein 2]]. This allows the transport of the [[calcitonin gene-related peptide type 1 receptor]] to the plasma membrane where the complex acts as a receptor for [[adrenomedullin]].



RAMP1

Fri, 23 Jun 2017 07:22:59 GMT

subclude

New page

{{GeneticsBox}}
[[Category:Genes]]
{{:Receptor activity-modifying protein 1}}



Receptor activity-modifying protein 1

Fri, 23 Jun 2017 07:22:08 GMT

for subclusion

New page


{{BiochemistryBox|||Calcitonin-receptor-like receptor activity-modifying protein 1, CRLR activity-modifying protein 1}}
[[Category:Transport proteins]]
[[Category:Transporter proteins]]
[[Category:Receptor proteins]]

The [[RAMP1]] gene at 2q37.3 codes for the 148 amino acid [[receptor activity-modifying protein 1]]. This allows the transport of the [[calcitonin gene-related peptide type 1 receptor]] to the plasma membrane where the complex acts as a receptor for [[Calcitonin gene-related peptide 1|calcitonin-gene-related peptide]].



Calcitonin-gene-related peptide

Fri, 23 Jun 2017 07:20:51 GMT

redirect

New page

#redirect[[Calcitonin gene-related peptide 1]]



Adrenomedullin

Fri, 23 Jun 2017 07:11:03 GMT

receptor

← Older revision Revision as of 07:11, 23 June 2017
Line 1: Line 1:
{{BiochemistryBox||ADM, AM, ADM2, Intermedin-long,IMDL, Intermedin-short, IMDS}}
{{BiochemistryBox||ADM, AM, ADM2, Intermedin-long,IMDL, Intermedin-short, IMDS}}
-
A protein family of hormone signal peptides related to [[calcitonin]]. An adrenomedullin receptor protein exists.
+
adrenomedullin is a protein family of hormone signal peptides related to [[calcitonin]]. The adrenomedullin receptor protein complex shares components with the [[calcitonin gene-related peptide type 1]] receptor.
==Adrenomedullin-1==
==Adrenomedullin-1==
Usually just termed '''adrenomedullin (AM, ADM)''' as it is in fairly high concentrations in the blood, it is a 52 aminoacid protein enzymatically formed from [[preproadrenomedullin]](ADM precursor) that acts as a :
Usually just termed '''adrenomedullin (AM, ADM)''' as it is in fairly high concentrations in the blood, it is a 52 aminoacid protein enzymatically formed from [[preproadrenomedullin]](ADM precursor) that acts as a :



CALCRL

Thu, 22 Jun 2017 22:39:55 GMT

subclude

New page

{{GeneticsBox|||CGRPR}}
[[Category:Genes]]
{{:Calcitonin gene-related peptide type 1 receptor}}



Calcitonin gene-related peptide type 1 receptor

Thu, 22 Jun 2017 22:38:25 GMT

for subclusion

New page


{{BiochemistryBox|||CGRP type 1 receptor, calcitonin receptor-like receptor}}
[[Category:Membrane proteins]]
[[Category:G-protein coupled receptors]]

The [[CALCRL]] gene at 2q32.1 codes for the 461 amino-acid [[calcitonin gene-related peptide type 1 receptor]]. This forms a heterodimer with its transport protein [[receptor activity-modifying protein 1]] that binds [[calcitonin gene-related peptide 1]] which is important in [[migraine]]. It also can form heterodimers with [[receptor activity-modifying protein 2]] and [[receptor activity-modifying protein 3]] to act as the receptor for [[adrenomedullin]] another vasodilator peptide.



Erenumab

Thu, 22 Jun 2017 22:23:27 GMT

will be more publicised next few days

New page

{{PharmacologyBox||AMG 334}}
Erenumab is a anti-CGRP monoclonal antibody that blocks the calcitonin gene-related peptide ([[Calcitonin gene-related peptide 1|CGRP]]) receptor which is a heterodimer of [[calcitonin gene-related peptide type 1 receptor]] and its transport protein [[receptor activity-modifying protein 1]]. It is in advanced development for the treatment of [[migraine]][https://www.ncbi.nlm.nih.gov/sites/entrez?itool=abstractplus&db=pubmed&cmd=Retrieve&dopt=abstractplus&list_uids=28460892 Tepper S, Ashina M, Reuter U, Brandes JL, Doležil D, Silberstein S, Winner P, Leonardi D, Mikol D, Lenz R. Safety and efficacy of erenumab for preventive treatment of chronic migraine: a randomised, double-blind, placebo-controlled phase 2 trial. The Lancet. Neurology. 2017 Jun; 16(6):425-434.](Print-Electronic) ([http://dx.doi.org/10.1016/s1474-4422(17)30083-2 Link to article] – subscription may be required.) with phase 3 trials complete. It is likely the dose will be 70mg monthly subcutaneously.
[[Category:neurology]]
[[Category:Monoclonal antibodies]]
{{refsec}}



Talk:Stalking

Thu, 22 Jun 2017 16:24:56 GMT

Created page with "Inspired by [https://m.facebook.com/groups/725958714116851?view=permalink&id=1569396369773077 a post] on the (closed) ''Resilient GP'' Facebook group."

New page

Inspired by [https://m.facebook.com/groups/725958714116851?view=permalink&id=1569396369773077 a post] on the (closed) ''Resilient GP'' Facebook group.



Stalking

Thu, 22 Jun 2017 16:18:34 GMT

Created page with "{{stub}} Doctors may have patients who are (or believe themselves to be) victims if stalking. They may also be victims themselves. Doctors' experiences of stalking range from ..."

New page

{{stub}}
Doctors may have patients who are (or believe themselves to be) victims if stalking. They may also be victims themselves.

Doctors' experiences of stalking range from inappropriate but harmless approaches approaches by patients through to a level of threat that makes it impossible to continue in practice.[https://www.google.co.uk/amp/s/amp.theguardian.com/society/2012/oct/28/lovesick-patients-stalk-doctors-online Denis Campbell. ''Infatuated patients use Facebook to stalk doctors''
27 October 2012 Guardian]
[http://www.itv.com/news/west/2016-04-06/doctor-stalked-for-seven-years-backs-calls-for-longer-sentences/ Doctor stalked for seven years backs calls for longer sentences. ITV news 2016]

Despite stalking being a criminal offence, there have been reports suggesting that police forces do not always take stalking seriously.

Some doctors have reported that a charity, [http://paladinservice.co.uk Paladin-National Stalking Advocacy Service], can provide valuable support to people experiencing stalking.




{{Refsec}}



Parental responsibility and parental rights

Wed, 21 Jun 2017 10:57:46 GMT

Parental responsibility: ← Older revision Revision as of 10:57, 21 June 2017 Line 3: Line 3: {{QuotationBox|The law in relation to parental responsibility has recently been revised. In relation to children born after 1 December 2003 (England and Wales), 15 April 2002 (Northern Ireland) or 4 May 2006 (Scotland), both of a child’s legal parents have parental responsibility if they are registered on the child's birth certificate. {{QuotationBox|The law in relation to parental responsibility has recently been revised. In relation to children born after 1 December 2003 (England and Wales), 15 April 2002 (Northern Ireland) or 4 May 2006 (Scotland), both of a child’s legal parents have parental responsibility if they are registered on the child's birth certificate. -Throughout the United Kingdom, a mother automatically acquires parental responsibility at birth. However, the acquisition of parental responsibility by a father varies according to where and when the child's birth was registered.|BMA[http://bma.org.uk/-/media/files/pdfs/practical%20advice%20at%20work/ethics/parentalresponsibility.pdf BMA. ''Parental responsibility: Guidance from the Ethics Department October 2008.'' Last viewed April 11 2015.]}}+Throughout the United Kingdom, a mother automatically acquires parental responsibility at birth. However, the acquisition of parental responsibility by a father varies according to where and when the child's birth was registered.|BMA ([[2008]])[http://bma.org.uk/-/media/files/pdfs/practical%20advice%20at%20work/ethics/parentalresponsibility.pdf BMA. ''Parental responsibility: Guidance from the Ethics Department October 2008.'' Last viewed April 11 2015.]}} Somebody with ''parental responsibility'' has 'all the rights, duties, powers, responsibilities and authority' that go with being a parent, and can give [[consent]] on behalf of a child who is a [[minors|minor]] (i.e. under the age of 18), and who lacks [[Capacity|capacity]] or [[Minors|competence]] to do so for him- or herself. Somebody with ''parental responsibility'' has 'all the rights, duties, powers, responsibilities and authority' that go with being a parent, and can give [[consent]] on behalf of a child who is a [[minors|minor]] (i.e. under the age of 18), and who lacks [[Capacity|capacity]] or [[Minors|competence]] to do so for him- or herself. [http://bma.org.uk/-/media/files/pdfs/practical%20advice%20at%20work/ethics/parentalresponsibility.pdf BMA. ''Parental responsibility: Guidance from the Ethics Department October 2008.'' Last viewed April 11 2015.] [http://bma.org.uk/-/media/files/pdfs/practical%20advice%20at%20work/ethics/parentalresponsibility.pdf BMA. ''Parental responsibility: Guidance from the Ethics Department October 2008.'' Last viewed April 11 2015.] [...]



Reports for the police

Tue, 20 Jun 2017 14:54:43 GMT

Other requests for information from the police: ← Older revision Revision as of 14:54, 20 June 2017 Line 50: Line 50: ==Other requests for information from the police== ==Other requests for information from the police==  +(Update - please note the statement from the BMA [[#Message from the BMA Professional Fees Committee, 20 June 2017|below]].)  + Sometimes police officer approach doctors and ask for information about their patients. Sometimes police officer approach doctors and ask for information about their patients. Line 62: Line 64: There is a useful scenario described by one of the [[Medical indemnity|medical defence organisations]] (the MDU) [http://www.themdu.com/guidance-and-advice/journals/inpractice-december-2013/disclosure-to-the-police here]. This also points out that it might be in the patient's interests to disclose information (e.g. to a [[Clinical forensic medicine|police surgeon]] - properly known as a forensic physician - so that appropriate care can be provided); but without the patient's consent such disclosure should be limited to the information that is needed for the purpose, and ideally should be given directly to the person to whom it is most relevant, such as a police surgeon or other appropriate healthcare professional. There is a useful scenario described by one of the [[Medical indemnity|medical defence organisations]] (the MDU) [http://www.themdu.com/guidance-and-advice/journals/inpractice-december-2013/disclosure-to-the-police here]. This also points out that it might be in the patient's interests to disclose information (e.g. to a [[Clinical forensic medicine|police surgeon]] - properly known as a forensic physician - so that appropriate care can be provided); but without the patient's consent such disclosure should be limited to the information that is needed for the purpose, and ideally should be given directly to the person to whom it is most relevant, such as a police surgeon or other appropriate healthcare professional.  +  +====Message from the BMA Professional Fees Committee, 20 June 2017====  +The following message was sent out by the [[British Medical Association|BMA's]] Professional Fees Committee on 20 June [[2017]]:  +  +:"The BMA professional fees committee has received new legal advice regarding medical note requests received from the police, which are detailed below.  +  +:"There is clear guidance regarding the obligations that GPs have with respect to copying and/or release of the GP record. For your reference, these circumstances are:  +  +:*"If the police do not have a court order or warrant they may request voluntary disclosure of a patient’s health records under section 29 of the Data Protection Act 1998.  +:*"However, while health professionals have the power to disclose the records to the police where section 29 applies, there is no obligation to do so.  +:*"In such cases health professionals remain bound by the long-established common law duty of confidentiality and may only disclose information where the patient has given consent, or there is an overriding public interest. They may also be required to defend their decision to disclose before the GMC which is a statutory tribunal.  +:*"Disclosures in the public interest based on common law are made where disclosure is essential to prevent a seriou[...]



Sus scrofa

Sun, 18 Jun 2017 10:00:45 GMT

start

New page

{{SpeciesBox}}
Pigs and wild boar. Their meat and secretions are a common cause of human disease, from influenza to worms.
[[Category:Zoonoses]]



Nipah virus

Sun, 18 Jun 2017 09:55:54 GMT

for info

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{{SpeciesBox}}
Nipah virus (Niv) is a virus of the genus ''Henipavirus'' transmitted from several bats including fruit bats of the Pteropodidae family, Pteropus genus (pteropid bats, flying foxes) in South East Asia. Human infection can be asymptomatic, associated with respiratory illness but also can have a high fatality rate from acute or relapsing encephalitis. Transmission is from exposure to fruit bat secretion (eg in date palm sap) or via intermediate hosts (pigs and man). Cases and the areas affected have increased since it was first identified in [[1998]][https://www.ncbi.nlm.nih.gov/sites/entrez?itool=abstractplus&db=pubmed&cmd=Retrieve&dopt=abstractplus&list_uids=10366143 Update: outbreak of Nipah virus--Malaysia and Singapore, 1999. MMWR. Morbidity and mortality weekly report. 1999 Apr; 48(16):335-337.](Print) whre pig meat exposure was important[https://www.ncbi.nlm.nih.gov/sites/entrez?itool=abstractplus&db=pubmed&cmd=Retrieve&dopt=abstractplus&list_uids=10520634 Paton NI, Leo YS, Zaki SR, Auchus AP, Lee KE, Ling AE, Chew SK, Ang B, Rollin PE, Umapathi T, Sng I, Lee CC, Lim E, Ksiazek TG. Outbreak of Nipah-virus infection among abattoir workers in Singapore. Lancet (London, England). 1999 Oct; 354(9186):1253-1256.](Print) ([http://dx.doi.org/10.1016/s0140-6736(99)04379-2 Link to article] – subscription may be required.). It is related to [[Hendra virus]] in Australia where the rapid characterisation of the epidemiology started much better understanding of bat transmitted virus infection[https://www.ncbi.nlm.nih.gov/sites/entrez?itool=abstractplus&db=pubmed&cmd=Retrieve&dopt=abstractplus&list_uids=28616459 Black P, Douglas I, Field H. This could be the start of something big-20 years since the identification of bats as the natural host of Hendra virus. One health (Amsterdam, Netherlands). 2015 Dec; 1:14-16.](Electronic-eCollection) ([http://dx.doi.org/10.1016/j.onehlt.2015.07.001 Link to article] – subscription may be required.). Proven hosts are:
* ''[[Pteropus hypomelanus]]'' (Island flying fox, variable flying fox)
* ''[[Cynopterus brachyotis]]'' (Lesser short-nosed fruit bat, ''Pachysoma brachyotis'')
* ''[[Eonycteris spelaea]]'' (Lesser dawn bat, ''Macroglossus spelaeus'')
* ''[[Pteropus vampyrus]]'' (Large flying fox)
* ''[[Scotophilus kuhlii]]'' (Lesser asiatic yellow bat)
* ''[[Sus scrofa]]'' (Pig)
* ''[[Homo sapiens]]'' (Human)
==Taxonomy==
{{TaxonomyParamyxovirinae}}
*******'''Genus''' ''Henipavirus''
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[[Category:Virology]]
[[Category:Emerging diseases]]
[[Category:Zoonoses]]
[[Category:Mononegavirales]]
[[Category:Paramyxoviridae]]
[[Category:Paramyxovirinae]]