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Last Build Date: Sun, 25 Feb 2007 03:05:09 GMT

 



Vaccine Against Colorectal Cancer

Sun, 25 Feb 2007 03:05:09 GMT

(image) British scientists have developed a vaccine that stimulates colorectal cancer patients' immune systems to fight malignant cells. In a clinical trial of 67 patients, scientists at the University of Nottingham found that when the vaccines were administered before and after surgery to remove malignant tumors, they helped stimulated immune cell production in up to 70 percent of patients. These results are reported in the November 15 issue of Clinical Cancer Research........



Virtual Colonoscopy More Expensive

Sun, 25 Feb 2007 03:05:09 GMT

(image) Wake Forest University Baptist Medical Center scientists have observed that "virtual" colonoscopy using a computer tomography (CT) scanner is considerably more expensive than the traditional procedure due to the detection of suspicious images outside of the colon. "Virtual colonoscopy will certainly play a role in the future of colon cancer screening," said gastroenterologist Richard S. Bloomfeld, M.S., M.D., assistant professor of medicine at Wake Forest Baptist and a member of the research team. "It is important to understand the implications of findings outside the colon before we advocate wide-spread use of this technology"........



New Way To Treat Colon Cancer?

Sun, 25 Feb 2007 03:05:09 GMT

(image) Scientists at University of Utah's Huntsman Cancer Institute have discovered a new target for possible future colon cancer therapys a molecule that is implicated in 85 percent of colon cancer cases. These findings were published online Oct. 6, 2006, in the Journal of Biological Chemistry. By knocking out that is, genetically disabling a molecule called C-Terminal Binding Protein (CTBP) scientists were able to rescue zebrafish from the effects of a mutation in the adenomatous polyposis coli (APC) gene........



Scientists Stop Colon Cancer Growth In Mice

Sun, 25 Feb 2007 03:05:09 GMT

(image) Scientists from Texas were able to stop the growth of colon cancer in mice by blocking just one enzyme. They say that this is a big step against conquering cancer. Even though this was an experiment on mice, these scientists hope that their findings might soon find its way to human cancers including colon cancer........



Curry And Onions May Prevent Colon Cancer

Sun, 25 Feb 2007 03:05:09 GMT

(image) A small but informative clinical trial by Johns Hopkins researchers shows that a pill combining chemicals found in turmeric, a spice used in curries, and onions reduces both the size and number of premalignant lesions in the human intestinal tract. In the study, reported in the recent issue of Clinical Gastroenterology and Hepatology, five patients with an inherited form of premalignant polyps in the lower bowel known as familial adenomatous polyposis (FAP) were treated with regular doses of curcumin (the chemical found in turmeric) and quercetin, an antioxidant in onions, over an average of six months. The average number of polyps dropped 60.4 percent, and the average size dropped by 50.9 percent, as per a team led by Francis M. Giardiello, M.D., at the Division of Gastroenterology, The Johns Hopkins University School of Medicine, and Marcia Cruz-Correa, M.D., Ph.D., at Johns Hopkins and the University of Puerto Rico School of Medicine........



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Sun, 25 Feb 2007 03:05:09 GMT

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Avastin And Taxol For Breast Cancer

Sun, 25 Feb 2007 03:05:09 GMT

Avastin, and anti-angiogenesis drug is now showing promise in the treatment of patients with metastatic breast cancer. A new research led by Dr Robin Zon, of Michiana Hematology-Oncology, PC in South Bend, Indiana has shown that combining Avastin with Taxol improves outcome in patients with metastatic breast cancer. The study has shown that a combination of Avastin and Taxol is more effective in prevention of progression of breast cancer compared to using Taxol alone........



Pharmacogenomics For Colorectal Cancer Treatment

Sun, 25 Feb 2007 03:05:09 GMT

University of Chicago scientists have licensed a genetic test that determines which patients are likely to have a serious adverse reaction to irinotecan hydrochloride (Camptosarandreg;), a key component of the standard first-line therapy for advanced cancers of the colon and rectum, to Mayo Clinic........



Merry Christmas To All Our Readers

Sun, 25 Feb 2007 03:05:09 GMT

Medicineworld wishes all our readers merry Christmas. Oh, jingle bells, jingle bells Jingle all the way......



Test For Patients With Colorectal Cancer

Sun, 25 Feb 2007 03:05:09 GMT

University of Chicago scientists have licensed a genetic test that determines which patients are likely to have a serious adverse reaction to irinotecan hydrochloride (Camptosarandreg;), a key component of the standard first-line therapy for advanced cancers of the colon and rectum, to Mayo Clinic.......



Computer-Aided Polyp Detection Software

Sun, 25 Feb 2007 03:05:09 GMT

A study led by the National Institutes of Health Clinical Center finds that computer-aided detection (CAD) software in conjunction with a procedure usually called virtual colonoscopy can deliver results comparable to conventional optical colonoscopy for detecting the most worrisome types of polyps.......



Preventing bowel cancer in high risk families

Sun, 25 Feb 2007 03:05:09 GMT

BOWEL cancer rates could be reduced by up to 80 per cent in people with a moderate family history of the disease by screening with colonoscopy, according to new research published in the British Medical Journal.*.But the research shows that most people, even those who have two or three relatives with the disease, do not need to be screened before the age of 45 or need to be screened very frequently.......



Adiponectin And Risk Of Colon Cancer

Sun, 25 Feb 2007 03:05:09 GMT

High plasma levels of adiponectin, an insulin-sensitizing hormone secreted by fat cells, are associated with a decreased risk of colorectal cancer, a new study has found.Adiponectin concentrations are inversely associated with body fat (that is, people with higher amounts of body fat tend to have lower circulating levels of adiponectin), and low levels of adiponectin are associated with insulin resistance and hyperinsulinemia. To determine whether plasma levels of adiponectin are associated with the risk of colorectal cancer, Esther K. Wei, Sc.D., of the Channing Laboratory at Brigham and Women's Hospital in Boston, and his colleagues compared the baseline plasma adiponectin levels of 179 men in the Health Professionals Follow-up Study who developed colorectal cancer with those of 356 men who did not develop cancer.......



Panitumumab Significantly Improves Progression-Free Survival in Metastatic Colorectal Cancer

Sun, 25 Feb 2007 03:05:09 GMT

Amgen and Abgenix, Inc. has recently announced that a pivotal Phase 3 study of panitumumab met the primary endpoint of improving progression-free survival in patients with metastatic colorectal cancer (mCRC) who had failed standard chemotherapy. In this randomized Phase 3 trial involving 463 patients, those who received panitumumab every two weeks showed a 46 percent decrease in tumor progression rate versus those who received best supportive care alone (p less than 0.000000001).......



Drink Coffee To Reduce Risk Of Colorectal Cancer

Sun, 25 Feb 2007 03:05:09 GMT

Drinking coffee may help prevent colon cancer, say German scientists, who have identified a potent antioxidant compound in the popular beverage that increased protection against the disease in animal studies.Researchers have suspected for years that coffee could offer some protection against cancer thanks to its high antioxidant content, but for the first time they identified a specific, highly active anticancer compound in the drink that boosts the activity of phase II enzymes.......