Thu, 25 Aug 2016 08:00:00 EDTThe invention relates to unpowered respiratory protective headsets for personal protective equipment and personal protective bodysuits with an unpowered respiratory protective headset.
Thu, 25 Aug 2016 08:00:00 EDTA system for delivering gas to a patient. The system includes a gas control unit, a breathing circuit, a control switch, and a patient interface. The gas control unit has a main gas outlet. The breathing circuit has a main gas line having a first end. The first end of the main gas line is coupled to the main gas outlet. The control switch may be a pneumatic switch, in which case the breathing circuit further has a pilot control line for pneumatically controlling the gas control unit to deliver gas to the main gas line via the main gas outlet. The control switch may be an electrical switch, in which case the breathing circuit may use electrical control of the gas delivery or electrical and pneumatic control of the gas delivery. Other embodiment of the gas control unit may include a continuous positive airway pressure branch.
Thu, 25 Aug 2016 08:00:00 EDTA high flow ventilation system delivers oxygen-enriched air to a patient at flow rates greater than 10 L/min using only conventional wall flow meters as found in most hospitals. The ventilation system combines the output of a plurality of wall flow meters into a specially configured gas mixing apparatus. The gas mixing apparatus provides oxygen-enriched air with an FiO2 (fraction of inspired oxygen) of approximately 21-100% with a total oxygen flow rate of 10-20 L/min or higher as required for high flow ventilation therapy. The oxygen-enriched air is delivered to the patient through a bite block device that allows insertion of an endoscope while simultaneously delivering high flow ventilation therapy to the patient through a large annular air flow passage around the endoscope.
Thu, 25 Aug 2016 08:00:00 EDTDescribed are systems and methods for compensating long term sensitivity drift of catalytic type electrochemical gas sensors used in systems for delivering therapeutic nitric oxide (NO) gas to a patient by compensating for drift that may be specific to the sensors atypical use in systems for delivering therapeutic nitric oxide gas to a patient. In at least some instances, the long term sensitivity drift of catalytic type electrochemical gas sensors can be addressed using calibration schedules, which can factor in the absolute change in set dose of NO being delivered to the patient that can drive one or more baseline calibrations. The calibration schedules can be used reduce the amount of times the sensor goes offline. Systems and methods described may factor in in actions occurring at the delivery system and/or aspects of the surrounding environment, prior to performing a baseline calibration, and may postpone the calibration and/or rejected using the sensor's output for the calibration.
Thu, 25 Aug 2016 08:00:00 EDTA medical headgear is disclosed having a flexible band having an inner surface and an opposite outer surface. The band includes a non-stretch central portion having a first side and an opposite second side, a first elastic portion connected to the first side, and a second elastic portion connected to the second side.
Thu, 25 Aug 2016 08:00:00 EDTTechniques for single lung ventilation (SLV) include a hollow main tube with outer diameter sized to fit inside a bronchus of a patient. The length of the main tube is sufficient for a distal end of the main tube to reach a first side bronchus from a proximal end configured to be located in a vicinity of a mouth of the patient. The hollow main tube has a ventilating orifice separated from the distal end at a location that corresponds to a different second side bronchus. A hollow tubular sleeve is moveably disposed inside and longitudinally aligned with the main tube. The sleeve is configured to be positioned in at least two positions: a first position that does not block the ventilating orifice; and, a second position that does block the ventilating orifice.
Thu, 25 Aug 2016 08:00:00 EDTA system adapted to regulate pressure of a flow of breathable gas generated by a motorized blower fan. The system may include a flow estimation analyzer adapted to receive a speed signal representative of a speed of the fan and estimate a parameter representative of the flow of breathable gas (e.g., a flow rate of the breathable gas). The parameter may be determined by inputting the speed signal into a function (e.g., an equation, matrix, or lookup table), which may be selected from a plurality of predetermined functions. The predetermined function may be selected based upon a specific characteristic of the speed signal as identified at the time of estimation of the parameter representative of flow.
Thu, 25 Aug 2016 08:00:00 EDTThis disclosure describes systems and methods for determining patient fatigue during ventilation of a patient. The disclosure describes novel notification and/or management of patient fatigue during ventilation. Further, the disclosure describes system and methods for preventing diaphragm fatigue or weakness.
Thu, 25 Aug 2016 08:00:00 EDTA barrier device used to perform ventilations on a victim undergoing cardiac arrest may be formed having similar dimensions as a standard identification card. Such a barrier device may also include identification information imprinted on a rear side, as well as instructions for how to perform CPR on a front side. A one-way valve is provided in the combined barrier device and identification card.
Thu, 25 Aug 2016 08:00:00 EDTA pulmonary drug delivery system is disclosed, including a breath-powered, dry powder inhaler, and a cartridge for delivering a dry powder formulation. The inhaler and cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, small organic molecules, peptides and proteins, including, insulin and glucagon-like peptide 1 for the treatment of disease and disorders, for example, endocrine disease such as diabetes and/or obesity.
Thu, 25 Aug 2016 08:00:00 EDTThe invention relates a metering device for fluids from a containment volume. The metering device is a means to dispense metered volumes of fluids such as detergents, medicaments, lotions and the like. The invention further provides a container for fluid material to be dispensed in metered doses.
Thu, 25 Aug 2016 08:00:00 EDTA vaginal laxity/uterine prolapse system is disclosed. The system includes vaginal laxity/uterine prolapse device and a suction device. The vaginal laxity/uterine prolapse device includes a shaft sized and configured for insertion into a patient's vagina. The shaft includes a plurality of suction ports. The shaft is coupled to a suction device to generate suction through the plurality of suction ports. The suction causes edema and increased blood flow to the vagina walls, resulting in an immediate increase in vaginal tone (“tightness”) and over time, with repeated use, causes hypertrophy of the vaginal wall and associated pelvic musculature, resulting in a permanent increase in vaginal tightness, significantly increasing the friction resistance to penile penetration. Use of the vaginal laxity/uterine prolapse system results in immediate and long-term increase in the frictional resistance and improved pelvic and vaginal muscle strength to prevent retrograde migration of the uterus into the vagina (uterine prolapse).
Thu, 25 Aug 2016 08:00:00 EDTDescribed is a penile implement that can be implemented as both a catheter device and a prophylactic device. The penile implement is formed of a top polyurethane film, with a bottom polyurethane film that is RF welded to the top film such that a reservoir exists between the films. An adhesive layer formed on the bottom film and a bottom release layer covers the adhesive layer. Further, a hole is formed in the bottom film. Thus, during use, a user may remove the bottom release layer and adhere the bottom film with a user's penis such that bodily fluids secreted from the user's penis pass through the hole and into the reservoir formed between the top film and bottom film.
Thu, 25 Aug 2016 08:00:00 EDTThe invention relates to a dental splint, comprising a base unit, in particular having dental splint plates irreversibly connected to each other, at least power supply unit, at least one signal generator, and at least one pressure sensor, which is operatively connected to the power supply unit and the signal generator, wherein the pressure sensor is designed in such a way that the pressure sensor detects both occlusion forces and protrusion forces acting on the pressure sensor.
Thu, 25 Aug 2016 08:00:00 EDTA medical injector for animals comprises a fixed body comprising a main housing which is made of a housing piece and another housing piece to form a hollow, a working rod placed in the hollow of the main housing and a restoration spring which is in the main housing to offer the restoration power to the working rod; a pressure unit comprising a pressure part which is inserted slidingly to a rear end of the main housing and is coupled integrally to an end of the working rod; and a handle which is formed integrally to the pressure part; a liquid injection unit comprising a liquid cylinder for forming a medical liquid chamber; and a needle unit which is coupled to a front side of the medical liquid cylinder; and a disinfectant spray unit coupled to the fixed body.
Thu, 25 Aug 2016 08:00:00 EDTThe invention relates to an oral insert for positioning between the outer faces of the teeth and the lips of a user, comprising a strip having a length and a width and an inner and outer face, wherein in the region of the longitudinal centre the longitudinal sides have an indentation. The oral insert further comprises at least one respiratory opening penetrating through the strip and a first and second bite projection which protrude from the inner face of the strip. The at least one respiratory opening is integrated in the first or second bite projection.
Thu, 25 Aug 2016 08:00:00 EDTA wound management device including: at least one securing element for securing to skin around a wound site;a chamber defining member connected to the at least one securing element for defining a chamber wherein the wound is accessible;wherein an opening is provided in the chamber so that access can be gained to the chamber, said opening being moveable between closed and open conditions, and there being at least one member for holding the opening in its open condition.
Thu, 25 Aug 2016 08:00:00 EDTA sterile barrier assembly, mounting system, and method for kinematically coupling first and second surgical components together through the sterile barrier assembly so that positioning is repeatable and deterministic.
Thu, 18 Aug 2016 08:00:00 EDT[Object of the Invention] An object of the present invention is to provide a breathing apparatus comprising a face piece for covering the whole face or part of the face provided with a hole at each side portion, a motor fan for supplying the face piece with external air, a pressure sensor for monitoring internal pressure of the face piece, a controller for controlling the operation of the motor fan based on a detection signal from the pressure sensor, a filter for purifying the external air supplied to the face piece, and an inhale valve and an exhale valve, wherein filter consumption is minimized. [Disclosure of the Invention] A breathing apparatus comprises a face piece for covering the whole face or part of the face provided with a hole at each side portion, a motor fan for supplying the face piece with external air, a pressure sensor for monitoring internal pressure of the face piece, a controller for controlling the operation of the motor fan based on a detection signal from the pressure sensor, a filter for purifying the external air supplied to the face piece, and an inhale valve and an exhale valve, wherein a positive pressure exhale valve is attached to one of the holes at the side portions of the face piece and a positive pressure exhale valve or a voice conductor is attached to the other of the holes at the side portions of the face piece.
Thu, 18 Aug 2016 08:00:00 EDTA fan filter device (50) for a respirator (1) includes an air inlet (54) for unfiltered air and an air outlet (56) for the discharge of filtered air. A fan unit (60), for aspirating air through the air inlet, includes a fan motor (62) and a fan sensor (64). The fan sensor is designed for detecting at least one operating parameter of the fan motor. The fan filter device further includes a filter unit (31) for receiving a filter (30) for filtering the aspirated air and an air flow sensor (58) for detecting at least one flow parameter of the filtered air flowing through the air outlet. A control unit (66) is configured to monitor the fan motor as a function of the at least one flow parameter and the at least one operating parameter. A respirator and method for operating such a fan filter device are also provided.
Thu, 18 Aug 2016 08:00:00 EDTA ventilator, or a breathing assistance apparatus, is provided to ventilate patients who may have breathing difficulties, said device comprising a inspiratory pressure control duct; a positive end-expiratory pressure control duct; at least one valve connected to the peak inspiratory pressure control duct and to the positive end-expiratory pressure control duct, and at least one controller communicably connected to the valve to control rate of cycling of the valve, thereby controlling number of breaths per minute, and to control the duration of peak inspiratory pressure also known as inspiratory time.
Thu, 18 Aug 2016 08:00:00 EDTA system for delivering oxygen to a patient through an airway includes an airway connector and a nasal cannula holder. The airway connector includes a first connector portion configured to be inserted into the airway, a second connector portion having an open end opposite the first connector portion, and a sample port disposed in a side of the second connector portion. The nasal cannula holder includes a first holder portion configured to connect to the second portion of the airway connector, a second holder portion connected to the first holder portion, and a nasal cannula port disposed in a side portion of the second holder portion configured to receive the nasal prongs of a nasal cannula to deliver oxygen to the patient.
Thu, 18 Aug 2016 08:00:00 EDTThis invention relates to a patient interface, such as a nasal cannula, comprising a body to be positioned upon a user (preferably such as a user's face), the body including at least one (and preferably a pair of) nasal prong(s), the or each nasal prong including a lumen capable of being fluidly connected thereto for fluid communication with a supply of breathable gas, the or each nasal prong to be in a configuration either inserted into, or to direct a flow of gas toward, a nare or the nares of the user's nose, wherein the body includes at least one element responsive to force(s) or movement(s), or both, experienced by at least a first region of the patient interface.
Thu, 18 Aug 2016 08:00:00 EDTA respiratory mask assembly for delivering breathable gas to a patient includes a frame to support one of at least first and second compliant patient interfaces and a forehead support adjustably mounted to the frame. The forehead support is structured and configured to be moved between a first position for use with the first patient interface and a second position relative to the frame for use with a second patient interface, whereby the forehead support maintains a horizontal offset distance with the first and second patient interfaces which is substantially constant.
Thu, 18 Aug 2016 08:00:00 EDTAn endotracheal tube securement device is disclosed. The device provides a sanitary and secure way to retain aft endotracheal tube. The device employs bite wedges to prevent a patient from biting the endotracheal tube, while providing an unobtrusive, comfortable and secure means for maintaining the endotracheal tube in place. The device is less visually traumatic than current arrangements. The device is small, with little to no facial contact, providing minimal obstruction of the oral cavity for hygiene and clinical management. The device has a first limb and a second limb joined at a junction that forms a rest for the endotracheal tube. There is a tube retainer attached to the tube rest. A first strut protrudes from the first limb to retain a first bite wedge, and a second strut protrudes from the second limb to retain a second bite wedge. A suction feature may also be provided.
Thu, 18 Aug 2016 08:00:00 EDTAn artificial airway device (1) to facilitate lung ventilation in a patient, comprising an airway tube (2) having a proximal end (3) and a distal end (4), a mask (5) at the distal end (4), and means (6) adapted to releasably confer rigidity to the airway tube (2) at least at, or towards its distal end (4) and also to provide a movable biteblock.
Thu, 18 Aug 2016 08:00:00 EDTDescribed here are devices, systems, and methods for positioning a suction catheter in the airway of a patient. The systems may comprise a suction catheter, a delivery device, and/or a stylet. The delivery device may comprise an elongate shaft, an atraumatic distal end, an elongate passageway, and a retention element configured to releasably couple to an endotracheal tube. The suction catheter may be positioned in the elongate passageway, and the delivery device may help advance the suction catheter into the airway of a patient. In some variations, the delivery device may comprise elements configured to release the suction catheter in the airway after positioning.
Thu, 18 Aug 2016 08:00:00 EDTA sterile and disposable ventilator is described in which all of the surfaces of the air-contacting component that contact patient airflow are sterile and disposable. A method of reducing or preventing ventilator cross contamination between a first patient and a second patient is also described that uses a sterile and disposable ventilator. The air-contacting component may be constructed in one-piece component and configured to operate with a mechanical ventilator component. The sterile and disposable ventilator of the present disclosure allows for efficient and cost-effective installation of a sterile air-contacting component that may be replaced between patients. The sterile and disposable ventilator reduces or eliminates ventilator inter-patient bacterial cross-contamination, and hospital-acquired infection rates may be resultantly lowered. Because current expensive bacterial air filters and other complex maintenance programs would be eliminated, the invention(s) of this disclosure also would simplify patient care and reduce cost.
Thu, 18 Aug 2016 08:00:00 EDTAn ultrasound scanning apparatus, a breathing machine, a medical system and a related method. The ultrasound scanning apparatus comprises an ultrasound scanning unit, an ultrasound controller for controlling the operation of the ultrasound scanning unit, detecting the operation state of the ultrasound scanning unit, generating a first enable signal when detecting that the operation state of the ultrasound scanning unit is transferred from an operating state to a nonoperating state and generating a second enable signal when detecting that the operation state of the ultrasound scanning unit is transferred from the nonoperating state to the operating state, and an enable output end for transmitting the first enable signal or the second enable signal to the breathing machine to control the running of the breathing machine.
Thu, 18 Aug 2016 08:00:00 EDTEmbodiments of an inhaler device include a housing, a withdrawing assembly disposed within the housing for facilitating withdrawal of medicament from a target blister of a blister strip, the withdrawing assembly including an opening element adapted for opening the target blister of the blister strip while the target blister is positioned in the withdrawing assembly, and a dispensing element adapted for directing the withdrawn medicament toward the exterior of the inhaler device. A blister track is disposed within the housing for guiding each blister of the blister strip to the withdrawing assembly in succession, an advancing mechanism for advancing the blister strip by a predetermined distance each time the advancing mechanism is engaged, and an engaging element for engaging the advancing mechanism to advance the blister strip. The blister track includes a primary coil structure, a secondary coil structure, and a tertiary coil structure.
Thu, 18 Aug 2016 08:00:00 EDTAn intravaginal device having an aperture and a withdrawal assembly. The withdrawal assembly has a withdrawal member and an obstruction.
Thu, 18 Aug 2016 08:00:00 EDTThe present invention relates to a medical body position retaining belt securing device. The medical body position retaining belt securing device is used for securing and releasing a medical body position retaining belt to and from an operating table side guide rail, wherein the medical body position retaining belt securing device comprises an upper clamping piece, a lower clamping piece and an elastic piece, the upper clamping piece or the lower clamping piece being coupled to the medical body position retaining belt, the upper clamping piece and the lower clamping piece being respectively provided with a clamping portion for clamping the operating table side guide rail, and two ends of the elastic piece respectively abutting against or being secured to the upper clamping piece and the lower clamping piece.
Thu, 18 Aug 2016 08:00:00 EDTAn animal intranasal administration device, and associated systems and methods, are disclosed. The animal intranasal administration device can include a nasal passage nozzle for each nostril configured to receive fluid from a fluid source. The animal intranasal administration device can also include a biasing mechanism to bias the nozzles toward a septum such that the device is secured in place about the septum during administration of the fluid into nasal passages.
Thu, 18 Aug 2016 08:00:00 EDTA surgical mask provides a wide range of wearers with a good fit and improved comfort, facilitates proper use of the mask, and reduces or eliminates fogging of eyewear, as compared with typical masks. The mask may include a pair of ties that are joined to the upper, central, and lower parts of either side of the body of the mask with the assistance of restraint members. The mask may also include a sealing member that reduces or eliminates gaps between the wearer's face and the upper part of the mask by forming a seal between the wearer's face and the mask in use. In addition, the mask may include a barrier panel that reduces or prevents the wearer's breath from escaping through the mask and rising to the wearer's eyewear.
Thu, 11 Aug 2016 08:00:00 EDTThe inflatable harness assembly for an aircraft oxygen crew mask includes one or more inflatable tubes having an outer layer of fabric material with an airtight coating for inflating the inflatable harness assembly. The inflatable tubes include an inner core of resilient, elastic material fixedly connected between first and second ends of the inflatable tubes that biases the inflatable tubes to shorten when the tubes are deflated. Inflation of the tubes them to expand the outer layer of material radially outwardly and lengthen axially, to allow the harness assembly to be placed over the user's head. Deflation of the tubes causes the aircraft inflatable harness assembly to grip the user's head with a desired head tension.
Thu, 11 Aug 2016 08:00:00 EDTThe current invention is system and device for a Self-Contained-Breathing-Apparatus (SCBA) emergency situation to solve the problem where a user is motionless and non-breathing. In order to hasten a Full Alarm activation and speed up the notification of distress to rescuers, in addition to the standard motion-sensing alarm, the SCBA shall be equipped with an ‘air activation’ alarm. Such ‘air activation’ alarm system shall monitor airflow to and from the user and activate if a user is not breathing.
Thu, 11 Aug 2016 08:00:00 EDTA humidification system can include a heater base, a chamber, and a breathing circuit. The heater base includes a heater plate positioned in a recessed region, and a heat conductive portion of the chamber is configured to contact the heater plate. The heater base includes a guard configured to control movement of the chamber into and out of the recessed region. The guard includes an anti-racking mechanism. The chamber includes an inlet port, an outlet port. A downward extension extends into the chamber from the inlet port, and a baffle is disposed at a lower end of the downward extension. A component of the breathing circuit can include a conduit hanging end cap for shipping and storage. The end cap can include a hanging component to allow the breathing circuit component to be hung from a medical stand. The system can detect when breathing circuits are connected in reverse.
Thu, 11 Aug 2016 08:00:00 EDTA system for inhalation, comprising gas supply apparatus configured to separately supply at least NO, and a carrier gas mixture which contains O2; a mixer apparatus configured for receiving gases from the supply apparatus and mixing the NO with the carrier gas mixture to provide a therapeutic mixture; an inhaler device configured for receiving the therapeutic mixture and releasing the therapeutic mixture in an enclosed space of the inhaler device; a chemical sensing assembly configured for providing data pertaining to a concentration of at least NO2 in the inhaler device; and a controller configured for controlling flow of the therapeutic mixture responsively to the data.
Thu, 11 Aug 2016 08:00:00 EDTA portable body-cooling device, comprises: a mask suitable to be positioned on the face of the patient and to cover its mouth and nose; a connector, suitable to connect said mask to a breathable gas container; and a gas container, containing a breathable gas in compressed state, which, when expanded, undergoes cooling. Also described is a method for reducing the body temperature of the patient in need thereof.
Thu, 11 Aug 2016 08:00:00 EDTA respiration insert includes a first portion sized to insert within an aperture of an induction mask formerly occupied by an anesthesia circuit. The respiration insert further includes a second portion coupled to the first portion and defining ports in fluid communication with a channel defined by the first portion. The ports may be embodied as tube stubs and may include an attachment interface for coupling to a CO2 monitoring system. A flange extends outwardly from the respiration insert and defines slots for receiving straps used to secure the respiration insert and induction mask to the head of a patient.
Thu, 11 Aug 2016 08:00:00 EDTAn angular interlock for a swivel feature formed using injection molding techniques is described herein. In one exemplary embodiment, the swivel feature is used for a conduit for delivering breathing therapy to a patient, and includes an outer swivel component and an inner swivel component formed using a two-shot molding technique. The outer swivel component is formed first out of a material, such as polycarbonate, having a low shrink rate, whereas the inner swivel component is formed of a material, such as polypropylene, having a high shrink rate. The material for the inner swivel component is injected into the formed outer swivel component and allowed to cool, creating a clearance. The outer swivel component includes an angular interlock protrusion that allows the inner swivel component to be formed without creating an interface about the angular interlock protrusion, which typically occurs with standard rectangular interlocks.
Thu, 11 Aug 2016 08:00:00 EDTA mask for supplying gas under pressure to an airway of a human including a flexible manifold shell, an air inlet connected to an air delivery pipe, and at least two side walls which are at least partially formed by portions of the manifold shell. A flexible face contacting element defines an orifice to accommodate the nose of the human. Straps connected to the mask allow forces exerted by the straps to deform the manifold shell at least along X and Y axes, creating a variety of different orifice shapes. The face contacting part includes a flexible membrane allowing X and Y axis movement of the mask and movement of the mask along a Z axis between the user's face and the manifold shell. The flexible membrane may deform while retaining a gas seal against the face of a wearer.
Thu, 11 Aug 2016 08:00:00 EDTNasal cannulas for providing respiratory therapy to patients can have a body, two prongs extending from the body, and a gases inlet on one side of the body. There can be a throttle or internal localized reduction in the cross-sectional area of a cavity defined by the internal walls of the cannula body in between the prongs. In at least some arrangements, the throttle can partially or substantially fully equalize flow between the prongs of the cannula.
Thu, 11 Aug 2016 08:00:00 EDTA method to immediately treat cerebral ischemia caused by hemorrhage, thrombosis or spasm is described. The method requires an apparatus comprising a tight fitting non-rebreathing mask with one way expiratory valves and a pressure regulated source of compressed oxygen. The mask may have an optional port for the administration of nitric oxide. Use of this apparatus can oxygenate and denitrogenate ischemic brain tissue and decrease infarct size. Little training is required for proper use of the apparatus which can be purchased for less than 75 USD in the United States. Similar to a fire extinguisher, this apparatus can be stored in the home and at work available for emergency use especially for those at high risk for stroke. A clinical trial should be conducted to assure that this therapy does no harm regardless of the etiology of cerebral ischemia. The cost of such a trial is not expected to be prohibitive and the institutional review board overseeing such a study should recognize the expected low risk to benefit ratio.
Thu, 11 Aug 2016 08:00:00 EDTThe present disclosure relates to a semi-malleable nasal mask system that has an internal support structure for providing a uniform-like sealing force around the user's nose and nose area.
Thu, 11 Aug 2016 08:00:00 EDTA method of sealing a trachea is provided that includes inserting a tracheal tube having an inflatable cuff made of a compliant material into a trachea. The method includes inflating the inflatable cuff with a fluid to a first pressure that exceeds a second pressure necessary to create a seal between the inflatable cuff and the tracheal wall. The method includes deflating the inflatable cuff by releasing a first pressure to allow the fluid to flow out of the inflatable cuff without applying vacuum pressure to the fluid while evaluating a rate of change of pressure of the fluid in the inflatable cuff. The method includes identifying a variance in the rate of change of pressure corresponding to a third pressure at which the inflatable cuff separates from the tracheal wall, determining the second pressure by analyzing the third pressure, and reinflating the inflatable cuff to the second pressure.
Thu, 11 Aug 2016 08:00:00 EDTA ventilation system for providing patient-triggered support ventilation to a spontaneously breathing patient during ongoing HFV ventilation has a pneumatic unit for delivery of breathing gas to the patient in response to an effort to breathe by the patient, a control computer for controlling the delivery of breathing gas by said pneumatic unit, and an oscillator for superimposing high frequency oscillation onto the breathing gas. The system further includes a bioelectric sensor that measures a bioelectric signal indicative of the patient's efforts to breathe, and the control computer is configured to control the delivery of breathing gas in response to the patient's effort to breathe, based on this bioelectric signal. The ventilation system is hence designed for neurally triggered support ventilation during ongoing high frequency ventilation, HFV, which makes the trigger mechanism of the ventilation system more precise and robust compared to trigger mechanisms of known ventilation systems capable of providing support ventilation during ongoing HFV ventilation.
Thu, 11 Aug 2016 08:00:00 EDTThe present disclosure pertains to a system (10) and method (500) to in-exsufflate a subject (12). The system provides an effective noninvasive alternative to invasive treatments such as a tracheostomy for ALS patients. The system detects airway collapse during exsufflation and adjusts in-exsufflation therapy settings to minimize airway collapse, thus maximizing the efficacy of the in-exsufflation therapy. In some embodiments, tidal volume, tidal flow rate, and/or other parameters are monitored (504) during in-exsufflation. Exsufflation pressure is adjusted (514) based on the monitored parameters to maintain an open airway during exhalation of the subject. Exsufflation pressure is adjusted based on a comparison (512) of an actual exhalation tidal volume to a target exhalation tidal volume, an actual exhalation flow rate to a target exhalation flow rate, an actual inhalation tidal volume to a target inhalation volume, and/or other comparisons.
Thu, 11 Aug 2016 08:00:00 EDTA breath-powered, dry powder inhaler, a cartridge, and a pulmonary drug delivery system are provided. The dry powder inhaler can be provided with or without a unit dose cartridge for using with the inhaler. The inhaler and/or cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, peptides and proteins such as insulin and glucagon-like peptide 1 for the treatment of diabetes and/or obesity. The dry powder inhaler is compact; can be provided in various shapes and sizes, colors, and comprises a housing, a mouthpiece, a cartridge placement area, and a mechanism for opening and closing the medicament cartridge. The device is easy to manufacture, provides a pre-metered single unit dose, it is relatively easy to use, and can be reusable or disposable.
Thu, 11 Aug 2016 08:00:00 EDTA thermally modulating inhalable medicament delivery device may deliver an inhalable medicament as an aerosol, vapor, or partial aerosol and partial vapor mixture. The inhalable medicament may be delivered to a target in a subject. Described herein are devices, systems, and methods for delivering an inhalable medicament to a subject.