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Mohawk-John Woods · Storify



Scientist, swing dancer, and violence prevention activist.



Last Build Date: Wed, 25 Apr 2018 06:13:37 GMT

 



#KScomplextraits

Sat, 25 Feb 2012 00:31:43 GMT

#storify-minimal a:hover{text-decoration:none}Keystone Symposia: Complex Traits. Breckenridge, Colorado.Storified by Mohawk-John Woods · Sat, Feb 25 2012 00:31:43Welcome to Breckenridge! It's a toasty 13 degrees with a -8 wind chill ⛄— Julie Huynh · Mon, Feb 20 2012 18:14:06#KScomplextraits keynote by Lee Hood about to start— Leonid Kruglyak · Tue, Feb 21 2012 02:18:01#KScomplextraits but first, the altitude sickness warning, since we are at 9700 feet— Leonid Kruglyak · Tue, Feb 21 2012 02:19:27Leroy Hood: Systems Approaches to Complex Diseases and the Emergence of Proactive P4 Medicine#KScomplextraits first network picture up: time to knock back a shot— Leonid Kruglyak · Tue, Feb 21 2012 02:43:20Hood @Keystone Biology is an information science, information is modular, circuitry (on a modular level) is conserved. #KScomplextraits— IyaKhalil · Tue, Feb 21 2012 02:47:58Hood - whole genome seq. of family of 4 allowed for use of Mendelian gen., ID of rare variants, & cross over points (Nice!) #KScomplextraits— Iya Khalil · Tue, Feb 21 2012 02:59:14Genomes should be seq. in families & it will need to be checked every year for newly discovered actionable variants #KSComplextraits— Iya Khalil · Tue, Feb 21 2012 03:06:01Next revolution is the #proteome - Hood creating digital reference of all human peptides #KSComplextraits— Iya Khalil · Tue, Feb 21 2012 03:11:34Hood's P4's goals is to quantify wellness and demystify disease. Hood is developing wellness parameters. #KSComplextraits— Iya Khalil · Tue, Feb 21 2012 03:22:13Hood's P4 Medicine interrogates a network of networks - genome, to your 'omit', phenome, organ, physiology, etc. #KSComplextraits— Iya Khalil · Tue, Feb 21 2012 03:23:59Mark McCarthy: Diamonds in the Dirt: Defining the Genetic Basis of T2D Susceptibility through Large-Scale Sequencing StudiesKari Stefansson is a no-show, so Mark McCarthy from Oxford is kicking things off at the first session of #KScomplextraits— Leonid Kruglyak · Tue, Feb 21 2012 15:02:49"MM" is Mark McCarthy.MM: most genetic action in T2 diabetes is in insulin secretion, prob related to failure of beta-cell development, function #KScomplextraits— Leonid Kruglyak · Tue, Feb 21 2012 15:05:28MM: if you've got mice in your clinic, that's not translational medicine, that's a problem in pest control! #KScomplextraits— Leonid Kruglyak · Tue, Feb 21 2012 15:06:07MM: over 60 known loci for T2D #KScomplextraits— Leonid Kruglyak · Tue, Feb 21 2012 15:07:08MM: no single path from normoglycemia to diabetes in man #KScomplextraits— Leonid Kruglyak · Tue, Feb 21 2012 15:14:15MM talking about how to get from GWAS hit to function: this is hard but making progress. #KScomplextraits— Leonid Kruglyak · Tue, Feb 21 2012 15:20:57MM: challenge: you need to look in the right species, right tissue, right developmental stage for functional effects. #KScomplextraits— Leonid Kruglyak · Tue, Feb 21 2012 15:25:02[...]