Subscribe: Animal Pharm
http://drbganimalpharm.blogspot.com/feeds/posts/default
Added By: Feedage Forager Feedage Grade B rated
Language: English
Tags:
bifidobacteria longum  bifidobacteria  episode  gut guardians  gut  high  part  podcast  potato starch  raw  starch  ubiome 
Rate this Feed
Rate this feedRate this feedRate this feedRate this feedRate this feed
Rate this feed 1 starRate this feed 2 starRate this feed 3 starRate this feed 4 starRate this feed 5 star

Comments (0)

Feed Details and Statistics Feed Statistics
Preview: Animal Pharm

Animal Pharm



The lessons science and pharmacology teach us about achieving optimal health, vitality and maximal lifespan with a low net carb, high saturated fat, evolutionarily paleolithic-styled diet aligned with my anc



Updated: 2017-12-10T19:13:30.991-08:00

 



Clinicians and Coaches: ROCK YOUR MICROBIOME & NUTRIGENOMIC MEDICINE w/ The Results & Outcome Academy Conference in 3 weeks

2016-11-20T11:14:49.751-08:00

Check out the updated site: TheGutInstitute.Com has launched!INVITATION TO COACHES AND PRACTITIONERS allowfullscreen="allowfullscreen" frameborder="0" height="113" src="https://www.youtube-nocookie.com/embed/CwFLZLbQ0ls?rel=0" width="200">Registration and More DetailsClinicians and Coaches:ROCK YOUR MICROBIOME and NUTRIGENOMIC MEDICINE w/ The Results & Outcome Academy Conference In 3 weeks!How to Grow Your Practice by Incorporating Microbiome & Nutrigenomic MedicineCost: VIRTUALLY FREE AND WORTH $2497Date: Dec 10th and 11th, 2016Location: Double Tree Hotel, Berkeley Marina, CaliforniaRegistration and More DetailsWhat Clinicians and Coaches Will Get!You will walk away with swag worth over $1000 – so the conference is virtually FREEKnowledge on how to build your businessCutting-edge, personalized gut and nutrigenomic protocols for your clientsA deep connection with new lifelong friends and future collaboration partnersPart of a growing emerging international community who are at the forefront of functional medicine for methylation and microbiome medicineThis an event like no other. We are bringing together leading practitioners, functional medicine providers, and health coaches to create a collaborative community.This will be transformational experience - if you plan to come and just sit in the seat and take notes – then this is not for you… You will not leave the same as you cameRegistration and More DetailsRegistration and More DetailsThis is Dr. Anh, and on behalf of Drs. Grace and Erika, I want to say “THANK YOU!” so much for your interest in our upcoming event, Microbiome and Nutrigenomic Medicine w/ Business Acumen live training!NEW SITE  TheGutInstitute.Com for the latest in microbiome, gut flora, science, podcasts and more![...]



Updates: New Website Launch THE GUT INSTITUTE.COM and Slides From PaleoFX Preso

2016-11-20T11:05:52.306-08:00

TheGutInstitute.Com has launched!Check out the iApothecary store for the ULTRA BIFIDO|MAXIMUS probiotic and many other gut microbiome and nutrigenomic tools to rapidly optimize your health! May you wealth and health be as marvelous as your microbes!Read about #BIONICFIBER and the special recipes you can make to make your gut microbiome bionic and bulletproof now---> Bionic Fiber Recipes for prebiotic power in your day for both you and your gut floraPlease migrate over there for all the latest news on the gut microbiome, studies, diagnostics, and gut protocol strategies for health optimization.We had an awesome turnout that was beyond capacity for the premiere ticket holders at PaleoFX this year: 'Shifting Your Gut Microbiota and Your 100 Trillion Friends for Leanness and Fat Loss'. Thank you for everyone that attended! The slides may be downloaded at TheGutInstitute.com (enter email). I am considering with Matt Pepin, my Gut Guardians co-host, to send out a monthly Gut RxTracts with a compilation of the latest gut news, research abstracts, book reviews, and all things poop and gut related. How does that sound? I'd love to know which topics you find most interesting.A couple of things I mentioned at PaleoFx:10% of uBiome analysis, thanks Eli and Paul~!http://ubiome.refr.cc/X4D28CW (Eli's referral code)http://ubiome.refr.cc/RW5Z7DX (Paul's referral code)Sources of chitin/chitosan for gut health and fat loss prebiotic effectsFiber in cricket flour is 7% and contains chitin/chitosanPubmed studies on fat loss and chitin/chitosanhttps://www.facebook.com/NextMillenniumFarmsSources of yacon in sugar free virgin chocolate in Raaka handcrafted bars (YUMMMM!) and 4 grams of yacon-FOS per half bar, thanks Bill~!10% off 'YACON10' codePrescript Assist, the only probiotic containing 2 strains of Bacteroides that is missing in nearly every study in overweight and obesity microbial signatures, one of the root problems in the obesity epidemic. This probiotic and other soil probiotics helped my family and I overcome gluten, dairy and other food intolerances so we could consume again on rare occasions without severe gut, brain or digestive issues.The company just the other day announced their evolution to ENVIRO MEDICA (no longer Magnetic Clay)! I love it! Congratulations!!http://www.magneticclay.com/store/prescript-assist-probiotic.aspxAO Biome, soil probiotic topical spray: Nitrosomonas, live Ammonia-Oxidizing Bacteria (AOB). It produces more NO, nitric oxide, a vital signalling molecule important for not just athletic workouts and sex ahah."This living product is a first, not only for our company, but for the industry as a whole. We created it to counteract the damage that modern lifestyles and products have on the biome, which often lead to irritation, sensitivity, and more. Our patented beneficial bacteria is similar to a probiotic, and it works to enrich your skin’s natural environment, gently restoring harmony to the skin. Specifically, it actively converts the byproducts of our skin (such as sweat) into beneficial ingredients, leading to skin that looks and feels great. "Mark Sisson's new soil based upgraded ultra high potency 10B CFU per cap -- used by Eli Markstrom, Spartan warrior in uBiome self experiment.http://www.primalblueprint.com/primal-flora/Check out the updated site: TheGutInstitute.Com has launchedThe HENRY Bar~!! My kids designed an energy bar that they will actually eat that's not full of non-Paleo junk. Thank you to my master tasters who gave it unanimous thumbs up -- my sisters, best galpals, Matt Pepin, Dr Emily Dean, Robb Wolf and CSA MMA gym (Kieran). Nearly all organic and non-GMO, the Henry is full of goodness like our puppy which it's named after. Check out TheGutInstitue.com later for more updates or contact me directly to get a box (I have some complimentary ones to send out!)Abundant in wonderful ingredients (some are not part of 7 steps -- dairy and nuts):17 grams isomalto-oligosaccharides (for fat loss, leanness and losing gut-leakiness) which is also found in f[...]



Heal Yourself Radio EP 002 - FROM DRUGS TO BUGS

2015-03-31T08:45:47.542-07:00

Heal Yourself Radio with chiropracter and hawt Crossfit athlete, Dr Jonathan Chung DC

EP 002 - FROM DRUGS TO BUGS

On this week’s episode of Heal Yourself Radio we’re talking to Dr. Grace Liu, a functional medicine expert with a doctorate in pharmacy. Her area of expertise involves the clinical applications of one of the hottest topics in science and medicine, the gut micro biome. This interview is full of great information about the importance of your gut bacteria, what foods to use to support it, and what to do if you’ve been on antibiotics. We also had a lot of fun talking about poop, whose poop Dr. Grace wants inside of her, and what might make my feces so interesting. It was a really fun interview, and I think you are all in for a little treat.

Save 10% on any uBiome kit or product with Dr.Chung's referral code
http://ubiome.refr.cc/638H9RC #microbiome



Gut Guardians Postcast: Episode 16 – (Part 2) Thyroid Help with Robin Treasure

2015-03-30T08:30:30.465-07:00

Gut Guardians Postcast: Episode 16 – (Part 2) Thyroid Help with Robin TreasurePart 1 Episode 15 – Gut Healing w Robin TreasureRobin Treasure in Part 2 offers her insights on how our guts might play a role in our thyroid health. She advises on the proper testings to diagnose a potential leaky gut causing poor adrenals. Yet another reason to keep your gut sealed up nice and tight.Be sure to check out Robin Treasures new program ‘Restore!’ to help build and nurture a healthier lifestyle.Don’t forget to leave any comments or suggestions! Enjoy!Show Notes:RobinTreasure.comRobin’s ‘Restore’ ProgramMatt’s source for making his bone brothKlaire ProbioticsAudio Player00:00Use Left/Right Arrow keys to advance one second, Up/Down arrows to advance ten seconds.00:00Use Up/Down Arrow keys to increase or decrease volume.Podcast: Play in new window | Download[...]



Gut Guardians Podcast: Episode 17- Gut-Brain Axis w Dr. Richard Matthews

2015-03-27T08:39:48.476-07:00

Gut Guardians Podcast: Episode 17- Gut-Brain Axis w Dr. Richard MatthewsFunctional Neurologist and author of The Symbiont Factor, Dr. Richard Matthews, joins in on the microbial fun. In this episode Dr. Matthews talks about the gut brain axis and multiple conditions that stem from the gut. Did we mention zombies? Matt and Grace had fun exchanging ideas on gut health and mental health.(Note: I had technical challenges, very sorry for the poor quality on my end. You’re not missing anything -- please enjoy Dr. Matthews and Matt).Thoughts on the Gut-Brain and parasitic gut zombies?Show Notes:Dr. Richard Matthew’s BlogAmazon: Book 'The Symbiont Factor'Twitter: @symbionthealthFacebook:  The Symbiont FactorCollective unconscious: How gut microbes shape human behaviorExcerpts from The Symbiont Factor“The Bacterial Ethernet”“Bacteria living within a colony are able to form interconnections between cells in a network, using very small microtubules that have been termed nanotubes (Dubey, Yehuda). These nanotubes allow bacteria to share information, which can take several forms. In one example, demonstrated by Ben-Jacob, bacterial colonies will self-organize into elaborate shapes to optimize their survival and will form complex networks of nanotubes where they share plasmids (small pieces of DNA) as well as other molecules from their cell.”“Providing a sustainable environment in the gut where good bacteria can flourish takes more work and lifestyle change than that and is one of the subjects of the rest of this book. Expecting the growth of beneficial bacteria without eating fruits, vegetables and fiber-containing grains is like scattering tomato seeds in a parking lot. Even though a few seeds might find some earth and germinate, you probably won’t get tomatoes unless you provide dirt, fertilizer, compost and water! Likewise, trying to get the good symbiont bacteria to grow without making improvements in your stress, diet and lifestyle is like trying to grow those seeds in the dark or on a parking lot.”[...]



New Podcast With Nourish Balance Thrive, Christopher Kelley: Have you checked your gut for the keystone species?

2015-03-20T08:19:04.394-07:00

Have you checked your gut for the keystone species? 

New podcast with elite pro mountain biker, Christopher Kelley of Nourish Balance Thrive and me (aka )



uBiome Analysis: Microbiome Hacking to Improve Gluten Intolerance and Acne

2015-03-30T08:04:33.991-07:00

uBiome BlogOur co-blog and Elijah's post on his recent gut uBiome results, here, at uBiome's blog today.His extended version at his blog: Microbiome Initial Data -- I Need a Recount"Observationally, I have noticed several changes so far. First and best, is that my sleep has been incredible. I fall asleep easily, sleep through the night and wake up with a pep in my step. Second, my appetite is lower. I feel full all the time. My energy levels are good. There is marginal fluctuation throughout the day. Third, my poop is more regular both in consistency and frequency."His earlier post at uBiome: How to Poop Well.Eli's uBiome 10% off referral codehttp://ubiome.refr.cc/X4D28CW[Side B: extended version, lol]Microbiota HackingThank you Elijah for the generous introduction! I appreciate your enthusiasm and reaching out to me to collaborate on maximizing gut health and your 100 trillion friends. Looking at uBiome stool analyses helps me to map out the bacterial terrain and landscape in the intestines. It is a ground breaking tool that I’m so grateful for. I look for landmarks and clues that tie in with published pyrosequencing studies.Elijah is an elite athlete with superior performance and 8-9% body fat. I almost doubted that we could further improve any biometrics (sleep, skin, mood, performance), but, naturally, when we look at the modern dysbiotic gut, everything can be improved. Modern guts are particularly vulnerable because they are being assaulted from all sides everyday. Therefore several simple and easy improvements can dramatically reset overall health by emphasizing our gut. Our gut is the initial site of nearly all disease (besides pure poisons). Our hunger, hormones, happiness chemicals and energy regulators all are controlled or composed by this master regulator organ that gut researchers call the ‘second brain’. Scientists report 80% of immunity is housed in the intestines. In my estimates, the gut doesn’t control all health, 24/7 all the time, but when it is disrupted, then ALL health may be disrupted. Whether you are an elite athlete like Elijah or a high-level executive or a super tiger-mom, a healthy gut lays the foundation for overflowing health, youthful energy, leanness and longevity. Our modern lifestyles lend characteristic changes in the microbiome – depletions of vital good flora and overgrowths of opportunistic pathogens. I call the good microflora ‘gut guardians’ because these protect our gut from birth until death. Their absence signals death, whether it’s a slow, gradual, perpetual and mildly painful death or a more chronic course riddled by the common American standbys: cancer, cardiovascular disease, autoimmunity, joint degeneration, or diabetes-obesity. Elijah’s gut profile exhibits the losses which everyone frequently experiences as a result of processed, refined carbohydrates, high sugar diets and use of antibiotics which were given for chronic ear infections as a child. His birth was C-section and studies show a lack of transfer of mom’s good microflora such as Bifidobacteria longum to baby without a vaginal birth.Landmarks that stand out on Elijah's gut microbiota uBiome analysis:low biodiversity (low phyla and species counts)depleted gut guardians which secure longevity and leanness by maintaining metabolism and a tight intestinal barrier             o Bifidobacteria (part of Actinobacteria: 3-fold below normal)              o Bifidobacteria longum (180-fold below optimal;                but at least its there! yay!)             o Bacteroides (3-fold below normal)             o Christensenella             o Akkermansiaincreased potential opportunistic bacterial overgrowths     [...]



Peering into Four uBiome Stool Analyses (Part 1): Benefits of BIONIC FIBER; Emergence of Toxin-secreting Clostridium Botulinum and Loss of Over 1/3 of Gut Diversity and Species With 'Raw Bob's Red Mill Potato Starch'

2015-03-09T12:32:32.791-07:00

Quantified Self Experimenter: R. Sprague Recently Richard Sprague shared his data with me and asked me to review his uBiome analysis of his stool microbiome. He's a bona fide data collecter and fan of QS (quantified self). The other day he shared his oral microbiome results. Lot of wonderful things going on there in his mouth! For his gut on potato starch, not so much. We will compare this gut results to two other uBiome samples from individuals taking a Bionic Fiber combination (psyllium, acacia, inulin-FOS, etc) and a diet based around the 7 Steps for an optimal gut microbiota.About Richard Sprague, 51 yr old QS-er, super healthy, lean (160 lbs, 6') and SUPER BRAINY:"At the time of the three samples, I did not take any supplements or other medication of any kind. I drink one cafe latte per day, plus about 5 servings of alcohol (usually beer) over the course of a week. I am an omnivore, though I tend toward paleo-style eating (no processed food, plenty of fat+meat). I eat wheat- and other gluten-bearing food a couple times a week, along with dairy, and I don’t notice any difference at all whether I abstain or not."Fiber intake (MyFitnessPal): 15-20 grams daily (below average; RDA for males 38 g/day, females 25 g/day if you subscribe to that) Three uBiome gut results:Sample taken on 5/16/2014 'Pre-RUMPS' (raw unmodified potato starch)Sample taken on 6/6/2014   (on travel, camping, varied diet)Sample taken on 10/17/2014  'Post-RUMPS' (raw unmodified potato starch 2-4 TBS) Prior to the Oct 2014 uBiome he used 2-4 TBS 'raw potato starch' (RUMPS) sporadically for about 2 weeks to hack his sleep and stools. Both had some quantifiable changes: sleep increased from 6.27 hrs/night to 6.52 hrs/night and stools increased from 1x/day to 2-3x/day. Quality of stools may have worsened; he reports Bristol 4 or 5 (mostly 5) prior to RUMPS and 5 after RUMPS. Below I review May and Oct results. Our gut biome changes hour by hour depending on diet and lifestyles. There are many 'drivers' but what we stick in our mouths is the biggest driver. I decided to only compare these May and Oct results as 'best' gut representatives. How Citizen Science Helps Us and Our Guts I love ubiome -- it is not diagnostic but it is a valuable tool that tells us the terrain of the lower gut and a little bit about the upper gut (small intestines). It gives us the profile for all the bacterial colonies in the colon. With tools that Richard developed on his github, one can integrate the raw taxonomy and play with them in Excel. (AmGut data FYI is not so simple). uBiome also has fantastic turnaround times -- only 2-3 wks for results to come back. I just submitted mine this week, and looking forward to pouring over it soon.  Fecal samples have limitations. They may or may not represent what is going on at the mucosa level. Sometimes vast changes are going on at the intestinal mucosal level but they don't spill over into the lumen and resultant fecal matter to truly tell us the representive microbial colonies going on there. Still I like poop. What we poop is what we are, just as what we eat is what we are. Diet is the biggest driver for shaping the gut microbiota. By just modifying diet and dietary supplements, we can perpetuate a better gut as well as better health. Another limitation is that looking at bacteria alone doesn't give us the big picture for life in our guts; non-bacterial colonies such as yeasts/candida, parasites, helminths, and protozoa are also significant contributors to gut health and dysbiosis and they're not not analyzed. These are better seen with a urine OAT (organic acid test) for clostridial and yeast metabolites or a specific Genova or Biohealth 401B parasite analysis.  The science is still in its infancy. uBiome and other institutions have not identified all the species. Depending on someone's gut com[...]



Gut Guardians Podcast: Episode 15 – Gut Healing w Robin Treasure

2015-03-04T12:15:26.977-08:00

Gut Guardians Podcast: Episode 15 – Gut Healing w Robin TreasureWellness specialist Robin Treasure joins the Gut Guardian Podcast to bring her expertise on healing the gut. Robin shares her best tips on which certain foods to avoid and which ones to add into the diet to help alleviate inflammation and heal the gut. She also gives warnings for those who may experience symptoms of a histamine intolerance when supplementing with probiotics.Don’t forget to leave any comments or suggestions! Enjoy!Audio Player00:00Use Left/Right Arrow keys to advance one second, Up/Down arrows to advance ten seconds.00:00Use Up/Down Arrow keys to increase or decrease volume.Podcast: Play in new window | DownloadShow Notes:RobinTreasure.comRobin’s ‘Restore’ ProgramMatt’s source for making his bone brothKlaire Probiotics[...]



Gut Guardians Podcast: Episode 14 – Genetics & Low Carb, SBO’s, and The Upper Gut w/ John Brisson

2015-02-26T10:45:36.009-08:00

Gut Guardians Podcast: Episode 14 – Genetics, Low Carb, SBO’s, and The Upper Gut w/ John BrissonThis is a wonderful gem, just like John Brisson!The Finale of the 3 part series with John Brisson of FixYourGut.com. In this episode, John talks with Grace and Matt about the Perfect Health Diet, Raw Milk, Genes and Low Carb Diets, SBO’s and much more! Don’t forget to check out John’s book, which is a great resource for anybody who would love to learn more about the gut and resolving gut troubles.Enjoy the episode!Show Notes:FixYourGut.comFixYourGut Book on AmazonPerfect Health DietAudio Player00:00Use Left/Right Arrow keys to advance one second, Up/Down arrows to advance ten seconds.00:00Use Up/Down Arrow keys to increase or decrease volume. Podcast: Play in new window | Download[...]



Gut Guardians Podcast: Episode 12 &13 – Probiotics, MAPS, and Ancestral Core; Flora Disruptors w John Brisson

2015-02-20T09:53:44.200-08:00

Gut Guardians Podcast: Episode 13 – Flora Disruptors w John BrissonFixYouGut.com’s John Brisson joins Matt and Dr. Grace on the GG podcast. In part 2 of the 3 part series, John and Grace talks about certain strains that are both detrimental and beneficial for proper gut function. Enjoy!Audio Player00:00Use Left/Right Arrow keys to advance one second, Up/Down arrows to advance ten seconds.00:00Use Up/Down Arrow keys to increase or decrease volume. Podcast: Play in new window | DownloadShow Notes:FixYourGut.comFixYourGut Book on AmazonGut Guardians Podcast: Episode 12 – Probiotics, MAPS, and Ancestral Core with John BrissonFixYouGut.com’s John Brisson joins Matt and Dr. Grace on the GG podcast. In part 1 of the 3 part series, John brings his insights and precautions on using certain probiotics. He also explains how he has had success treating clients with Crohns/Ulcerative Colitis. Dr. Grace and John also talk about their differences on what they believe to be “ancestral”. Don’t forget to rate and review the podcast. Enjoy!Show Notes:FixYourGut.comFixYourGut Book on AmazonMAP’s StudyAudio Player00:00Use Left/Right Arrow keys to advance one second, Up/Down arrows to advance ten seconds.00:00Use Up/Down Arrow keys to increase or decrease volume.Podcast: Play in new window | Download[...]



Gut Guardians DOUBLE Podcast Episodes: Diabetes, Fiber Diversity and the Gut Microbiota w/ Dr. Tim Gerstmar, Parts I and II

2015-02-05T08:37:56.914-08:00

Diabetes and the Gut Microbiota (Part 1) With Dr Tim Gerstmar NDThe Gut Guardians Podcast welcomes Dr. Tim Gerstmar (@DrTimGerstmarND) onto the show. He shares his insights on how he is treating his patients with diabetes and also gives us his take on the most recent findings that show the relationship between the gut microbiota and diabetes. Dr. Grace and Matt had a lot of fun chatting with Dr. Tim, as he brings his expansive knowledge to the show.  Enjoy!Audio Player00:00Use Left/Right Arrow keys to advance one second, Up/Down arrows to advance ten seconds.00:00Use Up/Down Arrow keys to increase or decrease volume. Podcast: Play in new window | DownloadFiber Diversity and the Gut Microbiota (Part 2) With Dr Tim Gerstmar NDThe conversation continues on the Gut Guardian Podcast with Dr. Tim Gerstmar. He gives both Dr. Grace and Matt a look inside of his “secret” jars. Well, looks like they aren’t going to be much of a secret after listening to this podcast! Inside the jars are Dr. Gerstmar’s special blend of fibers which range from FOS to glucomannan. Get your mason jars ready! Dr. Tim and Dr. Grace go back to the discussion on the mismatch between the modern human and the environments surrounding in and around us. And be sure to listen to the end, where Dr. Tim sums up what all of us should do to lead a happy, healthy life. Enjoy!Audio Player00:00Use Left/Right Arrow keys to advance one second, Up/Down arrows to advance ten seconds.00:00Use Up/Down Arrow keys to increase or decrease volume.Podcast: Play in new window | DownloadShow NotesDr. Tim Gerstmar’s Site Aspire Natural Health@DrGerstmarND and on Facebook PPARCronometerHUMAN STUDIES ON GLUCOMANNAN:[Dietary fiber in the dietetic therapy of diabetes mellitus. Experimental data with purified glucomannans].Konjac-mannan (glucomannan) improves glycemia and other associated risk factors for coronary heart disease in type 2diabetes. A randomized controlled metabolic trial.Beneficial effects of viscous dietary fiber from Konjac-mannan in subjects with the insulin resistance syndrome: results of a controlled metabolic trial.Konjac supplement alleviated hypercholesterolemia and hyperglycemia in type 2 diabetic subjects--a randomized double-blind trial.Effects of a stimulant-free dietary supplement on body weight and fat loss in obese adults: a six-week exploratory study. [glucomannan, chitosan, fenugreek, Gymnema sylvestre, and vitamin C]Effect of plant sterols and glucomannan on lipids in individuals with and without type II diabetes.Lack of translation between refined RS2 and RS3 animal studies to human trials:Sorry. Resistant Starch is Unlikely to Miraculously Cause Weight Loss and Body Fat LossLow (15g) and high dose (30g) RS2 for 4 weeks didn't induce fat loss either but mildly improved insulin resistance in obese men, not women (Maki et al, 2012).Neither did 25 grams refined RS3 supplementation (Novelose330), but high-protein/40% carbs resulted in all body fat parameters pivoting: improved insulin sensitivity, body fat loss and weight loss in human subjects with metabolic syndrome (Lobley et al, 2013).Neither did 40 grams RS2 supplementation for 12 weeks in T2 diabetes (Bodinham et al, 2014). Worsening in body fat mass, BMI, fatty organs such as fatty pancreas, also higher insulin secretion observed.GREEN BANANA FLOUR: However, a whole food supplement which contains a broad spectrum of microbial superfoods, native banana starch flour (NBS) 24 g/day induced 1.2 kg weight loss, improved waist-hip ratios and insulin sensitization in T2 diabetic, obese females after 4 weeks, contained only 8 grams RS2 (Ble-Castillo, 2010). Version B of BIONIC FIBER&n[...]



Lose Weight, Body Fat, Improve Blood Glucoses and Insulin Sensitivity; Repair the Gut Flora That Potato Starch (Raw RS2) Damages (Part VI)

2015-01-24T07:36:56.902-08:00

Part I: Bifidobacteria longum, Roseburia, F. prausnitzii (and Akkermansia) Made Us Human (NONE OF THESE EAT RAW POTATO STARCH) NSFWPart II: HADZA GUTS HAVE THE ANCESTRAL CORE MICROBIOTA IN ABUNDANCE; High Dose RAW Starch Can Suppress Bifidobacteria, Roseburia, F. prausnitzii That Make Us Human Part III: PALEO MAG HOT TONY FEDERICO HAS THE ANCESTRAL CORE MICROBIOTA IN ABUNDANCE; Citizen Science; Cautions with RPS-RUMPS; High Dose RAW Starch Appears to Suppress Christensenella, Akkermansia, and B longum That Make Us LEAN Part IV: High Dose Potato Starch Can Make You Fatter, Insulin Resistant, Feed Vipers in Your UPPER GUT If You Are MISSING Bifidobacteria longum and Akkermansia mucinophila, aka SAD Microbial Fingerprint  NSFWPart V: High Dose Potato Starch Can Make You Fatter, Insulin Resistant By Lowering GLP-1 AND ESPECIALLY If You Are Missing  Bifidobacteria longum and Akkermansia mucinophila, aka SAD Microbial Fingerprint NSFWDiabetes Warrior: Gut Experiment with Amped-Up Bionic FiberOur fearless low-carber Diabetes Warrior, Steve Cooksey, and I are doing a little n=1 experiment with an amped-up version of Bionic Fiber and the 7 Steps.  Bionic Fiber  replenishes the ancestral phylogenetic core microbiota which are damaged by SAD diets, antibiotics and high-dosage potato starch (raw resistant starch, type 2). These are the gut flora that also happen to regulate insulin and body fat storage.Steve uses a VLC (very low carb) diet to control blood sugars and successfully reversed obesity and complications related to diabetes. As 1/8 Cherokee Native American Indian, the VLC diet suits him well though he eats starches occasionally. Steve works out frequently and his diet includes a lot of greens including dandelion salads which are rich in inulin-FOS.Steve and Grace's Excellent AdventureDiabetes Experiment Update: Mr. '59'Amped Up Bionic Fiber (NOW Foods brand) + Bifidobacteria longum (LEF Bifido GI Balance)2 cups water and hydration during the day 1 tsp Acacia 1 tsp Inulin-FOS1 tsp Psyllium 1/4 to 1/2 tsp Glucomannan (avoid if trouble swallowing, dysphagia because this viscous fiber swells by 20-times in volume; max dose 1/2 tsp daily)Steve's results so far show reduction in weight prior to the holidays and no gains during the festivities. He was very pleased to see the blood glucoses (BG) improve from 70 - low 90s to 59 - 80s. Stools improved within 1-2 wks going from 3 times per week to daily.PROBLEM WITH POTATO STARCH? RAISES BLOOD GLUCOSES: FOLZ FAMILYIn the Folz Family RUMP/raw potato starch experiment, the family members all observed higher blood glucoses with 1 TBS potato starch except for Child 1 who was taking 1 TBS PSYLLIUM which has been shown to reduce body weight and blood glucoses. The n=1 are small but the point of the experiment was to measure BG as a metric of gut health. Adult 2 was trying to lose weight but no body fat losses or weight loss were reported during or after the 6 week experiment.HERE Allan Folz:First, our blood glucose measurements marginally went up, especially for my wife and me who were taking the largest doses. Before beginning the experiment I measured our BG first thing after waking up across three consecutive days. These were taken on January 15, 16, and 17.[PRE RESISTANT STARCH, RS2]For myself: 96, 89, 88For my wife: 89, 93, 101For child 1: 96, 91, 109For child 2: 84, 90, n/aAfter six weeks of RS I repeated taking some morning measurements. These were taken on March 26, April 1, 2, and 4.[POST RESISTANT STARCH, RS2]For myself: 97, 114, 94, 98For my wife: 116, 95, 92, n/aFor child 1: n/a, 92, 85, 89  [+ 1 TBS PSYLLIUM=IMPROVED BLOOD GLUCOSES]For child 2: 87, 90, 79, 100RAW STARCHES ARE[...]



PART II: Gut Guardians Podcast Episode 11 – Reinforcing Tribal Connections w Tony Federico

2015-01-21T09:44:30.282-08:00

Gut Guardians Podcast: Episode 11 – Reinforcing Tribal Connections w Tony FedericoPart 2 of Dr. Grace’s and Matt’s talk with Tony Federico.While most point to diet and exercise as key markers of achieving good health, Tony brings up another great aspect of living well: being apart of one’s community. A discussion on how tapping back into our roots can play an integral part of ones health. by helping and developing a sense of community with the ones surrounding gives us the same tribal setting as our ancestors.Gather some tubers, and huddle a group of your closest friends around the fire for this podcast!Show NotesTony Federico’s TwitterTony’s WebsitePaleo Magazine RadioPaleo GrillingDr. Grace’s Analysis of Tony’s Gut Test ResultsAudio Player00:00Use Left/Right Arrow keys to advance one second, Up/Down arrows to advance ten seconds.00:00Use Up/Down Arrow keys to increase or decrease volume.Podcast: Play in new window | Download[...]



Gut Guardians Podcast: Episode 10 – Tackling Resistant Starch and the Paleo Diet w Tony Federico

2015-01-15T14:56:47.234-08:00

Tony Federico, host of the Paleo Magazine Radio show, joins Dr. Grace and Matt to talk about his uBiome results. A possible beneficial strain Christensenella was abundant in Tony’s gut, which Dr. Grace goes into further detail. Tony talks beyond just Paleo, bringing insight to his day to day life, and how he maintains his healthy living. Tony asks Dr. Grace’s opinion on the potential effects of resistant starch and avoiding too many starches on a paleo diet.Enjoy Part 1!Photo CreditShow NotesTony Federico’s TwitterTony’s WebsitePaleo Magazine RadioPaleo GrillingChristensenella'Science writer Ed Yong says the Christensenellaceae bacteria might be a “keystone” species, “one that wields a disproportionate influence upon the world around it.”' Source: Genetic Literacy Project "Why do we gain weight or remain slim? Genes, microbes and now genes for microbes"Human Genetics Shape the Gut Microbiome (Ley et al, Cell 2014)Christensenellaceae associates with a lean BMIChristsenella reduce weight gains in germ-free transplant experimentsTony Federico'sChristensenellaceae 4.35% (5-fold higher; ubiome avg=0.844%)Christsenella 0.0224% (2-fold higher; ubiome avg=0.0120%)Dr. Grace’s warnings for using resistant starchPALEO MAG TONY FEDERICO'S uBIOME HAS THE ANCESTRAL CORE MICROBIOTA IN ABUNDANCE; High Dose RAW Starch Appears to Suppress Christensenella, Akkermansia, and B longum Gut Flora That Make Us LEAN (Part III)Audio Player00:00Use Left/Right Arrow keys to advance one second, Up/Down arrows to advance ten seconds.00:00Use Up/Down Arrow keys to increase or decrease volume. Podcast: Play in new window | DownloadLey et al, Cell 2014[...]



High Dose Potato Starch Can Make You Fatter, Insulin Resistant By Lowering GLP-1 AND ESPECIALLY If You Are Missing Bifidobacteria longum and Akkermansia mucinophila, aka SAD Microbial Fingerprint (Part V) NSFW

2015-03-09T11:05:55.179-07:00

Part I: Bifidobacteria longum, Roseburia, F. prausnitzii (and Akkermansia) Made Us Human (NONE OF THESE EAT RAW POTATO STARCH) NSFWPart II: HADZA GUTS HAVE THE ANCESTRAL CORE MICROBIOTA IN ABUNDANCE; High Dose RAW Starch Can Suppress Bifidobacteria, Roseburia, F. prausnitzii That Make Us Human Part III: PALEO MAG HOT TONY FEDERICO HAS THE ANCESTRAL CORE MICROBIOTA IN ABUNDANCE; Citizen Science; Cautions with RPS-RUMPS; High Dose RAW Starch Appears to Suppress Christensenella, Akkermansia, and B longum That Make Us LEAN Part IV: High Dose Potato Starch Can Make You Fatter, Insulin Resistant, Feed Vipers in Your UPPER GUT If You Are MISSING Bifidobacteria longum and Akkermansia mucinophila, aka SAD Microbial Fingerprint  NSFWPart V: High Dose Potato Starch Can Make You Fatter, Insulin Resistant By Lowering GLP-1 AND ESPECIALLY If You Are Missing  Bifidobacteria longum and Akkermansia mucinophila, aka SAD Microbial Fingerprint NSFW Intrepid gut explorer. Gut Tests Show Depletions of Akkermansia After Long Use of RUMPS, Which Appears to Correlate With Recent Bout 10 Lb Fat Gain/High Blood Sugars/Gout/Fatty Liver:    I love Tim S. and his intrepid gut testing. Several weeks ago, all the contents for this series and the past series (Parts 1-5) were run by and approved by Tim to discuss publicly. I brought up my observations and concerns very early on. He gave his approval to discuss all my concerns, precautions and problems for adverse effects generated by high dosage RS2 including concern for his liver, his high liver tests, SIBO/upper gut dysfunction, recent bout of 10 lb weight gain, gout, and fatty liver/NASH in June 2014, depletions of gut guardians including Akkermansia, and possible connections to the gut obesity fingerprint that is created with high dosage raw potato starch/RS2, the studies, the other N=1s, etc. He's the only person I know how has taken potato starch for over 1.5 years and his gut profiles are known with major depletions of vital 'Peacekeepers' (Faecalibacterium prausnitzii) and other immunoprotective species. Human and animal studies depletions of these gut species predispose to the conditions he developed: carbohydrate sensitivity, fat gain, fatty liver/NASH. Gut researchers have concluded that RS2 (type 2, raw; not cooked RS3) are not prebiotics and do not translate to humans. Metabolic function worsens in human randomized controlled trials.He is a bold citizen of science and declined the three times that I asked him if he wanted me to omit his data and carbohydrate/fruit related fatty liver/NASH.  His liver tests are better. One month ago, his liver test was still 35 and recently he reported it's now 15. He said "Grace has been privy to all of my gut tests, labs, and health concerns as a friend, not a doctor. I gave her express permission to discuss them how she sees fit. I think that this information needs to be shared freely. If I had a problem with any of this, Grace would be the first to know. I don't have a problem with her discussing me or my experiments. They are out there for everyone to see and interpret as they wish."How does the gut microbiota and what we feed it affect our health?Why does diet and dietary additions like supplements change in the composition and function of the gut?How does loss of diversity with a high dosage of a single source of 'fiber' adversely affect health? HIGH DOSAGE RAW STARCHES INCREASES BODY FAT IN T2 DIABETES SUBJECTS Bodinham et al 2014. Let's review. High dosage 40 g/day RS2 (high amylose maize) for 12 weeks increased resistance (HOMA) and lowered the fat-burning gut hormone known as GLP1. Post prandiall[...]



High Dose Potato Starch Can Make You Fatter, Insulin Resistant, Feed Vipers in Your UPPER GUT If You Are MISSING Bifidobacteria longum and Akkermansia mucinophila, aka SAD Microbial Fingerprint (Part IV) NSFW

2015-03-26T08:39:40.803-07:00

Part I: Bifidobacteria longum, Roseburia, F. prausnitzii (and Akkermansia) Made Us Human (NONE OF THESE EAT RAW POTATO STARCH) NSFWPart II: HADZA GUTS HAVE THE ANCESTRAL CORE MICROBIOTA IN ABUNDANCE; High Dose RAW Starch Can Suppress Bifidobacteria, Roseburia, F. prausnitzii That Make Us Human Part III: PALEO MAG HOT TONY FEDERICO HAS THE ANCESTRAL CORE MICROBIOTA IN ABUNDANCE; Citizen Science; Cautions with RPS-RUMPS; High Dose RAW Starch Appears to Suppress Christensenella, Akkermansia, and B longum That Make Us LEAN Part IV: High Dose Potato Starch Can Make You Fatter, Insulin Resistant, Feed Vipers in Your UPPER GUT If You Are MISSING Bifidobacteria longum and Akkermansia mucinophila, aka SAD Microbial Fingerprint  NSFWPart V: High Dose Potato Starch Can Make You Fatter, Insulin Resistant By Lowering GLP-1 AND ESPECIALLY If You Are Missing  Bifidobacteria longum and Akkermansia mucinophila, aka SAD Microbial Fingerprint NSFW IF VIPERS IN SMALL INTESTINES: Raw RS2Cooked RS3,StarchesKlebsiellaBacteroides-PrevotellaBacteroides E. coli, Other starch eaters YYYYYYYY VIPERS IN THE UPPER GUT (SIBO/SIFO) Early on, very few of the studies on RS2 showed fat loss, weight loss or significant metabolic improvements in any human trials I saw. No improvements in diabetes, insulin resistance, blood pressures, or blood cholesterol panels (triglycerides, HDL or LDL-cholesterols). This deep lack metabolic benefits for humans deviated from decades of studies using other types fiber and prebiotics (eg inulin, FOS, GOS, psyllium, beta glucan, etc). RS2 produced butyrate, but nearly all fiber and prebiotics produce butyrate. Gram for gram GOS, FOS-inulin and (pure) RS3 produce more butyrate than RS2. Beyond butyrate in the lower gut (colon), what benefits were there for RS2? Very few I found. And there is a cost -- RS2 at high doses compromises gut diversity and specifically the species that make us human and lean, fat-burning machines: Christensenella, Bifidobacteria longum, and AKKERMANSIA.  If there was fat loss or insulin improvements observed in animal studies with RPS or HAM-RS2, then the authors had poor study design -- they had substituted starch (digestible carbs) with RS2. In other words, they ran a VLC or LC (low carb) study, and we all know cutting refined rat chow carbohydrates will produce metabolic improvements, and often dramatic ones. When bifidobacteria and other guardians in the upper gut are removed by antibiotics, stress, high sugar diets and lack of vertical transmission from mom, the environment in the upper gut becomes vulnerable to opportunistic flora such as the organisms from the lower gut. They crawl up uninhibited. If acid, bile or the stomach's protein degraders (pepsin, trypsin, chymotrypsin) and pancreatic enzymes become compromised in secretion, they crawl up faster and more furious. If these vipers consume potato starch  or RS2 or high amylose maize, they will enjoy ultra fermenting this substrate and can create silent and insidious havoc in the intestines, particularly if the gut guardians are gone (Akk, B longum, lactobacilli, etc). There is a false 'myth', untruth pseudoscience that potato starch granules will 'carry' pathogenic bacteria away perpetuated on the internet.  Few vipers in the uppergut are 'carried away' from what I observe. Potato starch and raw starches ferments furiously and fervently where it lands. Worse, potato starch 'removes' the potent guardians of the uppergut, leaving the uppergut vulnerable to infections, E coli, fungi/candida and other potential commensals-turned-vipers and the vipers themselves. What protects vipe[...]



Gut Guardian Podcast: Episode 07 – Cracking Down on Candida

2014-12-12T09:37:03.314-08:00

Gut Guardian Podcast: Episode 07 – Cracking Down on CandidaThe yeast conversation continues as Matt asks Dr. Grace just how much truth is there to the candida epidemic. The symptoms are everywhere, but there is a bunch of skepticism along side the diagnosis of candida. Dr. Grace and Matt discuss how certain metals in the body can be detrimental in its harboring of candida. And for those who are having problems with candida, Dr. Grace offers her own experience and the methods she used to rid her problems. There is even more to be discussed on future episodes. Enjoy!Show Notes:Candida Resource containing information + botanicals Dr. Grace’s N=1 Blog Post00:0000:00Podcast: Play in new window | Download[...]



PALEO MAG HOT TONY FEDERICO HAS THE ANCESTRAL CORE MICROBIOTA IN ABUNDANCE; Citizen Science; Cautions with RPS-RUMPS; High Dose RAW Starch Appears to Suppress Christensenella, Akkermansia, and B longum That Make Us LEAN (Part III)

2014-12-11T13:49:44.386-08:00

Paleo MagTony FedericoAuthor of Paleo GrillingBEAUTIFUL GUTS, BEAUTIFUL MINDSMatt Pepin and I had the pleasure of having Tony on the show recently for the Gut Guardians podcast. Look out soon for it. We explored all sorts of paleo and ancestral themes particularlyTony's take on how we are so plugged in yet not getting the ancestral hits of oxytocin from face-to-face, voice or real contact. We also had the chance to review his uBIOME from earlier this year and why he felt that raw resistant starch was not ancestral, thus never partook. His bold piece on Resistant Starch (RS) was one of the first on the 'RS Cautions and Concerns', which also includes my early (unevolved) thoughts at the time.New evidence has presented, namely studies and citizen science (N=1, AMGut, uBIOME, Genova Diagnostic 2200 results) that use 16S rRNA analysis to detail and drill down what is occurring in the gut microbiota with RS2, raw starches, as a fiber and prebiotic and downstream effects.In the podcast we discuss more in depth revelations on this and why I think caution should be considered for situations when high dosage RS2 (raw starches) should be avoided, why, how, and what might be considered ancestral.He gave me permission to use his uBIOME and give my thoughts on his N=1. Luv citizen science.Currently I am preferring uBIOME over AmGut for mainly 2 reasons: (1) easy access to the detailed raw taxonomy to view down to species and genus depth, (2) turn around is fast. Like all testing, it's imperfect. Accuracy and sensitivity are likely limited like all testing by 20-30% if we are lucky. Comparisons between testing methods also restrict what conclusions we can make, and additional testing contaminants and other lab obstacles still clearly exist. Now onward and let's do the unscientific thing and compare apples with oranges!Placing Tony's 'Paleo Diet' column against the Hadza, healthy Mediterranean diet and the % of relative abundance in the healthy cohort reported by uBIOME, we can see how his gut size up, knowing this is provisional and only gives us 'patterns'. Functional medicine practitioners like myself compare gut species and phyla. With the upgraded Genova Diagnostic 2200 Stool GI Function testing it is possible to tie suboptimal health with the gut microbiota 'fingerprint'. By altering the 'fingerprint', better digestion, better health and performance can be obtained. Gut testing and knowing your gut 'fingerprint' is the future of all medicine because all health begins in the gut (Hippocrates).Here is a great manual, interpretative guide, see pg 21-25 to review Tony's data along with me. I would place 'green' as the above average measurements and 'red/yellow' as below average depending on the magnitude (eg 10-fold v. 0.2-fold reductions). Microbes magnify their populations by log scales, so below the representations are by 'fold' or 'times' expression.Tony's diet and lifestyle: no grains, no dairy, lots of non-starchy vegetables, fermented foods, meat, fat. He is also a personal coach and works out nearly daily with a lean BF of 14% and high muscle mass. Gut MicrobeLEAN ANCESTRAL COREANCESTRALGUT DIVERSITY?20-60g RS3Hadza TubersHEALTHY MEDITERR-ANEAN DIETItalian CohortuBiome NormalAvgPALEO DIETuBiome Non-starchy vegetables6ft, 190lbs, ~14% BFActive physicalFermented FoodsChristensenellaceaeChristensella----0.8440.01204.35 5X--ROCKSTAR0.0224 2X--The best levels I’ve seen STELLARAkkermansia----1.220.0488Bifidobacteria0.028.10.894%0.0010B.longumB.catenulatum----??0.4-0.5%--None0.0010Roseburia XIVa3.97.73.46%1.27Eubacterium XIVa2.21.40.912%5.97 6X Bla[...]



New Bulletproof Podcast with Dave Asprey: Dr. Grace Liu: Fixing the Gut Microbiome with Resistant Starch and Probiotics – #177

2014-12-06T10:19:43.521-08:00

Dr. Grace Liu: Fixing the Gut Microbiome with Resistant Starch and Probiotics – #177Click HEREHere are some resources that I discussed or were related:Yacon syrup: beneficial effects on obesity and insulin resistance in humans.  Inulin containing lowers body fat 33 lbs.Inulin-type fructans modulate intestinal Bifidobacterium species populations and decrease fecal short-chain fatty acids in obese women. Bifidobacteria longum significantly increased. Per author communication: Akkermansia increased too. BMI and insulin resistance all decreased significantly with inulin. Akkermansia and Bifidobacteria longum are associated with the lean core microbiota -- we want these for longevity and disease-free lifestyles as well.RS2 animal studies may not translate well to human application Animal studies show significant body fat and weight loss; however 4 human studies fail to replicate any improvementsCultivable and pyrosequenced fecal microflora in centenarians and young subjects.  High Bifidobacteria longum is extraordinarily characteristic in centenarians and corresponds with super low opportunistic gut growths.RS2-HAM high dosage 18% appears to lower important immunoprotective (human) core species: Bifidobacteria longum (but not animal ones), Roseburia cluster XIVa and F. prausnitzii Bifidobacteria longum appears to get starved and suppressed it seems per the authors' observations at high dosage RS2 18% and 36%. RS2 HAM does selectively feed good gut flora but these same populations also feed happily off starches, RS3 and inulin as well.In autoimmune, autism/spectrum, arthritis, IBS, IBD, GERD/heartburn and other inflammatory conditions, the RS2-eaters may predominate in a dysbiotic gut. Paleo guts often have these microbial 'signatures' I have noticed. RS2 may silently and insiduously worsen the microbial pattern so best to test, don't guess: GDX Stool 2200 and urine/blood NutriEvalMy body fat burning 'bionic fiber'= INULIN + AC (version B)Roseburia/XIVa protects and reverses peanut food allergies in recent animal modelAkkermansia is a key gut player for leanness and insulin sensitivityBifidobacteria longum in human studies improves many health parameters (anxiety, high cholesterol, low HDL, high triglycerides, gut dysbiosis, fungal infections, IBD, IBS, GERD/heartburn, diabetes, obesity, metabolic disorders) including also significantly the gut inflammation related to gluten/gliadin.[...]



HADZA GUTS HAVE THE ANCESTRAL CORE MICROBIOTA IN ABUNDANCE; High Dose RAW Starch Can Suppress Bifidobacteria, Roseburia, F. prausnitzii That Make Us Human (Part II)

2014-12-06T12:07:32.932-08:00

Baobab TreeHarvested by Hadza: fruit, seeds, honey, bark, etc COOKING BROADENED HUMAN UTILIZATION AND FORAGING OF WILD AND TOXIC PLANTSLet's neo-romanticize the Hadza hunter-gatherer studies for a moment. They eat a diet rich in starchy tubers, raw roots, chewing some of the tough, fibrous ones for several minutes, extracting as much starch, nutrients and energy as they can. The carbohydrate content varies from 27 to 70% of the tuber (see chart at end). Fiber varies from 3-35%. Cooking generally breaks tough fibers down. Stewing, boiling and roasting all make these more easily chewable and thus digestible.Fermentation does as well. Paleophil has a short list of tubers that are fermented to process them into safe to eat starches (truly ancient 'safe starches' lol). Several varieties were put underground and allowed to pickle/ferment to remove toxins. The great majority of tubers on earth are toxic if raw. Nature provided underground protection for them. Potatoes contain trypsin and protease inhibitors (never fed raw to livestock or eaten by humans raw) and cassava, cyanide derivatives.  In Africa, co-evolution of consumption of toxic cassava may have actually conferred an advantage by improving sickle cell anemia. On the other hand, trypsin inhibitors in yams and potatoes are heat labile and easily deactivated by cooking. Heat rapidly degrades these toxins, making them safe for eating for everyone: small toddlers, children, elderly and adults.In Africa and the tropics, extracts from toxic potatoes and yams can even be isolated for use in making poison arrows for hunting wild game.RS3 AND RS2 FEED DIFFERENT FLORA IN THE GUTCooked starches with skins feed the great majority of our gut flora whereas raw, native starches feed only a few (but important few). From recent gut profiles from individuals who submitted samples to Genova, uBIOME and American Gut, a distinct pattern emerges if a high-dose raw resistant starch diet is implemented. Diversity is markedly low. The immunoprotective Roseburia/clostridia XIVa are missing. Is Roseburia important? I think so -- it is one of the strains that make us human, no hamsters or chimps. See prior post: Bifidobacteria longum, Roseburia, F. prausnitzii (and Akkermansia) Made Us Human (NONE OF THESE EAT RAW POTATO STARCH) (Part 1) NSFWN=1, THREE HIGH-DOSE RS2 INTREPID SELF-EXPERIMENTERSHere are 3 individuals (reports: a, b, c) who biohacked their guts and used high dose RS2 for a period of time before submitting stool samples to various testing groups: uBIOME, American Gut.Bacteroidetes-Prevotella and Bacteroides overlap -- they both consume RS2 heartily and easily, as you can see below. On the other hand, the great majority of the core ancestral microbiota do not and with report c, one may observe that even consuming significant fiber as RS3, the Roseburia fails to 'bloom' in the gut. Normally RS3 (alone, sans RS2) feeds or cross-feeds Roseburia extensively based on Alan Walker et al research group. These 2 groups Prevotella and Bacteroides are big starch eaters of cooked digestible carbohydrates as well as resistant starch (cooked cooled, RS3). So they eat EVERYTHING. This is what I have an overgrowth of on/off the last few years of gut healing (and didn't realize). Prevotella is implicated in many cases of dysbiosis and uppergut overgrowths (SIBO/SIFO). Ck out pubmed: Prevotella/dysbiosis.--T2 diabetes/Obesity--colorectal cancer--T1 diabetes--IBD (Crohn's, UC)--IBS-C IBS-D--colorectal cancer--HIV infectionWhen I saw the Prevotella on [...]



New GG Podcast: EPISODE 06 WEED THY GUT

2014-11-17T21:25:36.945-08:00

Gut Guardian Podcast: Episode 06 – Understanding Yeasts and Skin FloraYeasts, they are in our breads, beers, and in and on our body. Matt asks Dr. Grace how to deal with lingering skin issues that he attributes to yeasts. Dr. Grace explains tips on how to distinguish if skin issues are caused by a topical problem or a deeper issue residing in our guts. And just when you thought probiotics would only work for your gut, there is a formula for your skin flora!Enjoy the episode!Show NotesInformation on YeastsDr. Graces Recommended Hair Treatment Another Skin Flora Helper (Apply to Skin/Scalp before bed and wash in morning)AOBiome00:0000:00Podcast: Play in new window | Download[...]



Bifidobacteria longum, Roseburia, F. prausnitzii (and Akkermansia) Made Us Human (NONE OF THESE EAT RAW POTATO STARCH) (Part 1) NSFW

2014-11-10T08:25:25.728-08:00

allowfullscreen="" frameborder="0" height="169" src="https://www.youtube.com/embed/djMvXCRhvp0" width="300">Journal Club today:Moeller et al PNAS 2014 'Rapid changes in the gut microbiome during human evolution'Fig 1. Compositional changes in the gut microbiome during African ape diversification. Shifts in relative abundances of microbial genera within the gut microbiome were inferred for each branch of the host phylogeny. Genera whose relative abundances increased or decreased are listed above or below each branch within blue-shaded or yellow-shaded boxes, respectively.Moeller et al PNAS 2014Ancestral Core:Roseburia, F. prausnitzii, BIFIDOBACTERIA,Bacteroides, ClostridiumHighlights:Ancestral Core:Roseburia, F. prausnitzii, BIFIDOBACTERIA, Bacteroides, ClostridiumThe ancestral core made us human. These are enriched 2 to 5-fold in humans through deep evolutionary time compared to our wild African chimp and ape cousins. These gut flora eat a range of plant polysaccharides but the more immunoprotective, the more they are likely to consume breastmilk-like oligosaccharides (inulin type fructans, GOS, raffinose family oligosaccharides) and inulin. Roseburia, F. prausnitzii, BIFIDOBACTERIA and Clostridium thrive and crossfeed on RS3 and inulin/oligosaccharides, but not raw starches/RS2."Changes in the composition of the microbiome accrued steadily as African apes diversified, but human microbiomes have diverged at an accelerated pace ow- ing to a dramatic loss of ancestral microbial diversity. These results suggest that the human microbiome has undergone a substantial transformation since the human–chimpanzee split.""For instance, the relative abundances of Prevotella and Bacteriodes were negatively correlated within each host population."  Prevotella are high grain-eaters, seen high in Burkina Faso children and those consuming whole-grain-based diets. Bacteroides are versatile -- they consume everything: carbs/grains, fats,  andmeat/protein."Relative abundances of Bacteroides were always positively correlated with those of Ruminococcus and Parabacteroides."  Bacteroides again are big meat-and-potatoes fans. "We identified 35 instances in which the relative abundance of a microbial taxon shifted since the divergences of the extant species of African ape (Fig. 1), 17 of which occurred in humans since the divergence of Homo and Pan. Several of these changes in the composition of the human microbiome have functional implications for host nutrition." The introduction of diverse, high-fiber, high-RS3 cooked starches changed many things for humans including the evolution of their gut flora: seeds (lotus, quinoa, fenugreek, buckwheat, etc), legumes, lentils, roasted tubers-rhizomes, whole soaked nuts, ground nut flours (tigernut 'cakes', acorn 'pancakes'), maize (porridges, tortilla), whole grains (oats, millet, maize, sorghum, teff, amaranth, black/red/brown/purple rices), etc.Humans Expanded Their Food and Ecological Niches By Taming Fire Whole Real Food100g = ~ ½ cupInulin-Oligosaccharide ContentRS3 ContentChicory root100g41g  0Jerusalem artichoke100g18g  0Dandelion greens100g13g  0Onion (raw or cooked)100g4g    0Garlic (raw or cooked)25g3g  0Cowpea, White Lupin100g5g4gLentils, Chickpeas, Hummus100g4g2-4gPinto Beans (cooked/cooled)100g3g  10gPurple Potato (roasted/cooled)100gna15-19gYams (boiled/cooled)100gna6-8gPotato (boiled/cooled)100gna[...]



UPDATES: Current LiveFeed with AmGut Scientists! Also The Gut Guardian Podcast: Episode 05 – WEED THY GUT

2014-11-06T10:24:55.318-08:00

----------------------------------------NOW!: Post any questions for American Gut researchers!Jamie Binn at Redefining Human has set up an AMA (ask-me-anything) for us and other curious gut explorers! Thank you so much Jamie!Go to twitter.com and please post with #redefininghuman hashtag. I've posted a few already this morning.SEARCH: https://twitter.com/search?q=%23redefininghumanDaniel is #3 at AmGut, super geeky nerdy comp sci. Enbriette is a hard core biologist.----------------------------------------Don't forget to look at their Kickstarter and being a citizen researcher on the gut. I just signed up for some kombucha and the $250 level (will get my name on their episode).KICKSTARTER for REDEFINING HUMAN: THE MICROBIOME DOCUMENTARY----------------------------------------The Gut Guardian Podcast: Episode 05 – WEED THY GUTTest results are in. You’ve got overgrowths of the wrong microbes. Dr. Grace and Matt examine the process of weeding out these misplaced microbes and recreating a symbiotic gut flora. Testing is the first step, and after listening to this episode you will have the tools needed to begin your weeding process.Enjoy the episode!Show NotesRSS FEED: http://restoretheflora.com/feed/podcastCLICK, GO STRAIGHT TO iTUNES Dr. Grace’s Interview with Dave Asprey (talk about gut biohacking, failing PS, weeding, 6-pack abs after weeding and probiotics) Sorry the audio from China was subpar.Which testing you need to getGreat weeding information by Dr. Grace here and here00:0000:00Podcast: Play in new window | Download[...]



The Gut Guardians Podcast: Episode 04 – THE ULTIMATE GUT GUARDIAN...BIFIDOBACTERIA

2014-11-02T17:05:57.973-08:00

Episode 04 – The Ultimate Gut Guardian: BifidobacteriaSBO’s are usually the key probiotics for those experiencing gut troubles. Matt on the other hand, wants to share how Bifido played a key role in his recovery. Grace explains why it was the missing link in his recovery. Bifido wasn’t just helpful for Matt, but as Grace explains, it is truly one our bodies biggest gut guardians. Oh and they LOVE CARBS. You’ll find out all about the wonders Bifido provides for our guts in this episode.Enjoy!(Sorry -- play arrow not work)00:0000:00Podcast: Play in new window | DownloadShow Notes:RSS FEED: http://restoretheflora.com/feed/podcastCLICK, GO STRAIGHT TO iTUNES Grace’s Recommended ProbioticsGut Guardian Podcast on INULIN (EPISODE 02) Renew Life Critical Care[...]