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Preview: Comments on Weight of the Evidence: Protein Provides Satiety Through PYY

Comments on Weight of the Evidence: Protein Provides Satiety Through PYY





Updated: 2017-12-15T19:26:57.661-06:00

 



What Katherine said reminds me of what the Eades s...

2008-01-16T12:42:00.000-06:00

What Katherine said reminds me of what the Eades say about blood pressure meds. You go into the doctor, your blood pressure is a bit high. The doc prescribes a beta blocker. It artificially forces your blood pressure down, but it doesn't address the root cause of high blood pressure, which is insulin-induced sodium retention by the kidneys.

Furthermore, the beta blocker increases insulin resistance, which tends to increase insulin production. Now you are at increased risk of metabolic syndrome. Your cholesterol goes up. The doctor prescribes another drug, which has insulin resistance as a side effect.

A few more rounds of this, and pretty soon you have Type II diabetes. If, however, your doctor had put you on a low-carb diet at that first visit (and, of course, if you'd followed his advice), your blood pressure would've normalized and you would not be playing the ratcheting-up-the-insulin-resistance game.

I do agree with logos that not everyone is willing to make lifestyle choices, and some people would rather take a pill. However, I wonder if people's perspectives would change if their doctors said, "The diet will fix you up pretty much completely with minimal side effects, but you stick to it for the rest of your life; the pill will allow you to continue living the way you do, but it has many side effects that include insulin resistance. Insulin resistance can lead to obesity, heart disease and Type II diabetes, which in turn can lead to tendon and joint problems, gangrene, amputations, kidney failure, blindness, and early death. Shall I get out the prescription pad?"



The thing though with an satiety indicator which i...

2008-01-16T04:32:00.000-06:00

The thing though with an satiety indicator which is active in repsonse to the food a person eats is that it works in balance with other changes in metabolism and body chemistry. That we know little about this balance and how other, perhaps as yet unknown, proteins or hormones are affected is irrelevant - the changes occuring are a result of homeostatic processes which take place in response to the nature of food eaten.

Stick in an artificial satiety agent, which is based on one released naturally in reponse to one diet, while the person eats an entirely different diet and there is no way of knowing what the knock on effects on blood chemistry and homeostasis will be.

In this context the distinction between natural and artificial seems pretty clear.



I just found your blog today and am rather enjoyin...

2008-01-15T14:24:00.000-06:00

I just found your blog today and am rather enjoying reading your usually quite analytical approach.

However, I would say that your suggestion here that drug analogues of GI hormones the stimulate satiety are necessarily bad because there exists a dietary alternative is rather like the assertions that proponenets of low fat diets makes. Specifically, the implication that everyone can successfully loose weight using a low fat diet, while technically true, does not necessarily make it the best choice for any given patient. I would suggest that hormone analogues for weight loss may play a usefull role in weight loss treatment in the future. Certainly because a certain way of eating works for maintaining a reasonable weight for you and I does not necessarily mean that another method will not be efficacious for others.

I also tend to take issue with the implication that "natural" is necissarily better than "artificial", both of which are highly subjective terms.



Hi, Regina,I find your blog amazingly useful and i...

2008-01-15T10:42:00.000-06:00

Hi, Regina,

I find your blog amazingly useful and informative, and I've featured in my new Blog Spotlight series.

Enjoy!