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Last Build Date: Sun, 25 Feb 2018 21:27:03 +0000

 



Comment on TWiV 482: Don’t EVEome without antibody expressed by TWiV 482: Don’t EVEome without antibody expressed - VETMEDICS

Sun, 25 Feb 2018 21:27:03 +0000

[…] The TWiV Masters discuss serologic evidence of Ebolavirus infection in a population with no outbreaks, and the set of endogenous viral elements in the mosquito genome. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: […]Source link […]



Comment on Ebolavirus infections but no outbreak by Ebolavirus infections but no outbreak - VETMEDICS

Fri, 23 Feb 2018 04:48:01 +0000

[…] Ebolavirus infections are feared because of the high fatality rate observed during outbreaks, from 25-90%. But there is evidence that far less serious Ebolavirus infections may occur in the absence of outbreaks. The latest study was conducted in late 2007 and comprised 3415 subjects living in 14 rural villages in the Kasai Oriental Province of […]Source link […]



Comment on Ebolavirus infections but no outbreak by Ebolavirus infections but no outbreak - Virology

Fri, 23 Feb 2018 02:06:54 +0000

[…] Ebolavirus infections are feared because of the high fatality rate observed during outbreaks, from 25-90%. But there is evidence that far less serious Ebolavirus infections may occur in the absence of outbreaks. The latest study was conducted in late 2007 and comprised 3415 subjects living in 14 rural villages in the Kasai Oriental Province of […] Source link […]



Comment on Trial By Error: A Letter to BMJ Open by Rivka

Tue, 20 Feb 2018 13:16:53 +0000

When do theses malice actions on the part of the medical community cross the line into criminal acts? Their targets are sick children and their desperate bewildered parents.



Comment on Trial By Error: A Letter to Archives of Disease in Childhood by Trial By Error: A Letter To BMJ Open – The York ME Community

Tue, 20 Feb 2018 07:01:36 +0000

[…] weeks ago, Professor Racaniello e-mailed a letter of concern to Archives of Disease in Childhood about its recent study of the Lightning Process as a […]



Comment on Trial By Error: A Letter to BMJ Open by Trial By Error: A Letter to BMJ Open - VETMEDICS

Tue, 20 Feb 2018 00:54:50 +0000

[…] By David Tuller, DrPH Three weeks ago, Professor Racaniello e-mailed a letter of concern to Archives of Disease in Childhood about its recent study of the Lightning Process as a treatment for ME/CFS in kids. The journal’s editor, Dr. Nick Brown, answered within an hour, assuring Professor Racaniello that he took the matter seriously and […]Source link […]



Comment on Trial By Error: A Letter to BMJ Open by Trial By Error: A Letter to BMJ Open - Virology

Mon, 19 Feb 2018 17:45:45 +0000

[…] By David Tuller, DrPH Three weeks ago, Professor Racaniello e-mailed a letter of concern to Archives of Disease in Childhood about its recent study of the Lightning Process as a treatment for ME/CFS in kids. The journal’s editor, Dr. Nick Brown, answered within an hour, assuring Professor Racaniello that he took the matter seriously and […] Source link […]



Comment on Trial By Error: A Letter to BMJ Open by Joan byrne

Mon, 19 Feb 2018 17:07:39 +0000

Excellent letter and thank you for writing this Prof Racaniello. It is hard to believe that the BMJ would publish such an unethical piece of work. Let us hope they see immediate sense and acknowledge their grave error in doing so. Time to right the wrong.



Comment on TWiV 481: And biles to go before I delete by TWiV 481: And biles to go before I delete - Virology

Mon, 19 Feb 2018 04:41:35 +0000

[…] The TWiVodrome considers the intestinal tract as an alternative infection route for MERS coronavirus, and how reduced accumulation of defective viral RNAs might lead to severe influenza. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; […] Source link […]



Comment on TWiV 481: And biles to go before I delete by TWiV 481: And biles to go before I delete - VETMEDICS

Sun, 18 Feb 2018 22:32:18 +0000

[…] The TWiVodrome considers the intestinal tract as an alternative infection route for MERS coronavirus, and how reduced accumulation of defective viral RNAs might lead to severe influenza. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; […]Source link […]



Comment on Defective viral genomes and severe influenza by Defective viral genomes and severe influenza - VETMEDICS

Fri, 16 Feb 2018 07:15:37 +0000

[…] The virulence of a virus – its capacity to cause disease – is determined by both viral and host factors. Even among healthy individuals, infection with a particular virus may have different outcomes ranging from benign to lethal. The study of influenza viruses that cause mild or fatal outcomes reveals that defective viral genomes play […]Source link […]



Comment on Defective viral genomes and severe influenza by Defective viral genomes and severe influenza - Virology

Thu, 15 Feb 2018 23:34:07 +0000

[…] The virulence of a virus – its capacity to cause disease – is determined by both viral and host factors. Even among healthy individuals, infection with a particular virus may have different outcomes ranging from benign to lethal. The study of influenza viruses that cause mild or fatal outcomes reveals that defective viral genomes play […] Source link […]



Comment on Trial By Error: QMUL and FOI; Nature and Cochrane; the Pineapple Fund by Nina

Thu, 15 Feb 2018 09:30:09 +0000

Thank you Virology blog and David!!!



Comment on Trial By Error: QMUL and FOI; Nature and Cochrane; the Pineapple Fund by Trial By Error: QMUL and FOI; Nature and Cochrane; the Pineapple Fund - VETMEDICS

Wed, 14 Feb 2018 04:45:42 +0000

[…] By David Tuller, DrPH Queen Mary University of London seems to have devised a fail-safe method of avoiding having to comply with more PACE-related freedom-of-information requests—just declare no one is around who can deal with it. Earlier this month, the U.K. Information Commissioner’s Office issued a decision in an appeal of QMUL’s rejection of a […]Source link […]



Comment on TWiV 480: The PFU in your achoo by TWiV 480: The PFU in your achoo - VETMEDICS

Mon, 12 Feb 2018 01:51:07 +0000

[…] Scott Hensley joins the TWiVites to review the current influenza season and presence of the virus in exhaled breath of symptomatic cases. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&gt;&lt;/span&gt;&amp;lt;span data-mce-type=”bookmark” style=”display: […]Source link […]



Comment on TWiV 480: The PFU in your achoo by TWiV 480: The PFU in your achoo - Virology

Sun, 11 Feb 2018 20:52:59 +0000

[…] Scott Hensley joins the TWiVites to review the current influenza season and presence of the virus in exhaled breath of symptomatic cases. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&gt;&lt;/span&gt;&amp;lt;span data-mce-type=”bookmark” style=”display: […] Source link […]



Comment on A breath of fresh influenza virus by A breath of fresh influenza virus - Virology

Sat, 10 Feb 2018 01:43:13 +0000

[…] Influenza virus may be transmitted among humans in three ways: by direct contact with infected individuals; by contact with contaminated objects (called fomites, such as toys, doorknobs); and by inhalation of virus-laden aerosols. A recent study suggests that normal tidal breathing plays a substantial role in aerosol transmission. Volunteers in a college community were screened for […] Source link […]



Comment on A breath of fresh influenza virus by A breath of fresh influenza virus - VETMEDICS

Fri, 09 Feb 2018 23:08:26 +0000

[…] Influenza virus may be transmitted among humans in three ways: by direct contact with infected individuals; by contact with contaminated objects (called fomites, such as toys, doorknobs); and by inhalation of virus-laden aerosols. A recent study suggests that normal tidal breathing plays a substantial role in aerosol transmission. Volunteers in a college community were screened for […]Source link […]



Comment on Trial By Error: Letter to British Journal of Sports Medicine from CPET Experts by 18.1治療ガイドライン(案)に対する海外の意見③ | NPO法人 筋痛性脳脊髄炎の会(ME/CFSの会)

Wed, 07 Feb 2018 13:18:20 +0000

[…] http://www.virology.ws/2018/02/05/trial-by-error-letter-to-british-journal-of-sports-medicine-from-c… http://www.workwellfoundation.org/wp-content/uploads/2017/07/GETSET-Trial-in-MECFS-L1.pdf […]



Comment on Trial By Error: Letter to British Journal of Sports Medicine from CPET Experts by leelaplay

Tue, 06 Feb 2018 19:19:00 +0000

Thank you Workwell and David for this letter. Well done. I hope that the BJSM has the ethics to publish it soon. If not, is there another avenue to get it published now that pubmed commons is no longer publishing comments?



Comment on Trial By Error: Letter to British Journal of Sports Medicine from CPET Experts by leelaplay

Tue, 06 Feb 2018 19:10:00 +0000

Anton, Workwell has a number of publications and videos that address this linked to on their site.



Comment on Trial By Error: A Letter to Archives of Disease in Childhood by Dis Bins

Tue, 06 Feb 2018 16:28:00 +0000

Such a clear explication of the bias in this study. Have they no shame in endangering very sick children in this way. Bravo for pointing out the errors and for collecting a truly impressive list of signers!






Comment on Trial By Error: Letter to British Journal of Sports Medicine from CPET Experts by disqus_joh5XNAv6w

Tue, 06 Feb 2018 12:19:00 +0000

"This is a very useful tack in as much as it both highlights the prejudices of the Cochrane review and hopefully piques the interest of a discipline which I have long felt might be very curious to investigate this disease more closely." _ I agree and suggest this is offered to the NICE SCoping Exercise?



Comment on Trial By Error: Letter to British Journal of Sports Medicine from CPET Experts by Anton Mayer

Tue, 06 Feb 2018 11:51:00 +0000

Thank you for this letter. Can anyone summarize how one can train the anaerobic energy system?



Comment on Trial By Error: Letter to British Journal of Sports Medicine from CPET Experts by pinklil

Tue, 06 Feb 2018 10:11:00 +0000

This is a very useful tack in as much as it both highlights the prejudices of the Cochrane review and hopefully piques the interest of a discipline which I have long felt might be very curious to investigate this disease more closely. In the same way Cheney had problems convincing his cardiologist peers that people with ME could have a positive bubble test, whilst simultaneously appearing to be hale and hearty on the usual bank of hospital cardio tests, until those cardiologist peers had seen the evidence with their own eyes, maybe sports scientists could be encouraged to look at the impaired physiology of people with ME using the technologies at their disposal and thus also believe what VanNess et al have described here? They might be able to elucidate extra fundamental flaws in the way people with this disease use, or don't use, energy. I suppose how the BJSM react to this letter rather depends on how open minded they are to the scientific method and proper scientific enquiry rather than, possibly, toeing a line handed to them by others with a vested interest in maintaining the status quo & who would prefer a discipline such as 'sports medicine' (with its bias toward *objective* measurements ;) ) to not interfere and threaten their subjective, un-blinded junk-science 'data base'.



Comment on Trial By Error: Letter to British Journal of Sports Medicine from CPET Experts by Valentijn

Tue, 06 Feb 2018 08:26:00 +0000

Simon Wessely was one of the founders of that Cochrane group. No doubt the intent was to prevent honest and impartial review from other groups better suited to handling a disease with neurological, muscular, and immunological components.






Comment on Trial By Error: Letter to British Journal of Sports Medicine from CPET Experts by Olivia Beatty

Tue, 06 Feb 2018 07:18:00 +0000

Apparently the German equivalent of UK NICE has just approved CBT/GET as the recommended treatment in it's recent review.



Comment on Trial By Error: A Letter to Archives of Disease in Childhood by JustinReilly

Tue, 06 Feb 2018 04:46:00 +0000

Wow! Thanks to all for this great letter!



Comment on Trial By Error: Letter to British Journal of Sports Medicine from CPET Experts by JustinReilly

Tue, 06 Feb 2018 04:41:00 +0000

Very cogent letter. Thanks for posting!



Comment on Trial By Error: Letter to British Journal of Sports Medicine from CPET Experts by tomkindlon

Tue, 06 Feb 2018 01:28:00 +0000

Very good letter. Small point: I am surprised to see the "ibid" format being used. I'm not sure I have ever seen it used in the many hundreds of medical and scientific papers I have read. I have certainly not used it in the letters I have had published.



Comment on Trial By Error: Letter to British Journal of Sports Medicine from CPET Experts by Wendy Boutilier

Mon, 05 Feb 2018 23:14:00 +0000

Canada turned down an ME Study a couple of years ago because the Cochrane Review suggests GET and CBT. They felt we didn’t need another “fatigue” Study.



Comment on Trial By Error: Letter to British Journal of Sports Medicine from CPET Experts by mesupport

Mon, 05 Feb 2018 22:29:00 +0000

The Cochrane review appears in the Common Mental Disorders Group totally ignoring WHO G93.3 classification as a neurological condition.



Comment on Trial By Error: Letter to British Journal of Sports Medicine from CPET Experts by Fiona

Mon, 05 Feb 2018 22:22:00 +0000

Terrific letter from Workwell/UoP - it encapsulates a lot of what this disease is, and explains clearly why aerobic exercise is bad news for PWME. Thanks for publishing!



Comment on Trial By Error: Letter to British Journal of Sports Medicine from CPET Experts by Wendy Boutilier

Mon, 05 Feb 2018 22:13:00 +0000

The review was funded by £206,000 (US$304,087 ) from the UK National Institute for Health Research. What could possibly go wrong when the Heroes of the the PACE Trial Study - the UK Psychiatric Collaborative wrote the Cochrane Protocol for people with Chronic Fatigue Syndrome as well as for people with Myalgic Encephalomyelitis ???? Every other country adopted it without question.



Comment on Trial By Error: Letter to British Journal of Sports Medicine from CPET Experts by Robert McMullen

Mon, 05 Feb 2018 22:11:00 +0000

Excellent letter. Many thanks to all.



Comment on Trial By Error: Letter to British Journal of Sports Medicine from CPET Experts by Peter Trewhitt

Mon, 05 Feb 2018 22:05:00 +0000

Thank you for publishing this clear and concise account of why aerobic exercise is contra indicated in ME/CFS and why the studies advocating GET are profoundly flawed. It is a great shame it was not published in the BJSM. Let's hope this Blog series is read by the clinicians and researchers that continue to advocate GET.



Comment on Trial By Error: Letter to British Journal of Sports Medicine from CPET Experts by Star Man

Mon, 05 Feb 2018 21:59:00 +0000

"Our experiences working with ME/CFS patients are that graded exercise – particularly aerobic exercise–not only fails to improve function, it is detrimental to the health of patients." Thank you to the University of the Pacific and the Workwell Foundation for this letter. The lack of effectiveness and potential potential for harm from GET need to be continually pointed out until doctors take notice. Hopefully one day soon, healthcare providers (such as Kaiser Permanente and its 12 million members), will stop recommending GET for their ME/CFS patients.



Comment on Trial By Error: Letter to British Journal of Sports Medicine from CPET Experts by Sleepyblondie

Mon, 05 Feb 2018 21:58:00 +0000

Thank you. This is a never ending battle to stop medical professionals from harming us and I am so grateful that you listen and help to speak for us



Comment on Trial By Error: My Six-Month Review by GQ

Mon, 05 Feb 2018 15:33:00 +0000

Thank you Dr Tuller for "vexatiously" advocating for thousands of disabled ME sufferers who have have been harmed for years by the Biopsychosocial psychiatrists and exposing this major medical abuse and financial fraud.



Comment on TWiV 479: Trypsin the flight fantastic by TWiV 479: Trypsin the flight fantastic - VETMEDICS

Mon, 05 Feb 2018 03:24:00 +0000

[…] The TWiVome explores induction of antiviral responses by repeating patterns of capsids, and a fungus in the mosquito gut that aids dengue virus replication. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&gt;&lt;/span&gt;&amp;lt;span […]Source link […]



Comment on TWiV 479: Trypsin the flight fantastic by TWiV 479: Trypsin the flight fantastic - Virology

Sun, 04 Feb 2018 16:47:33 +0000

[…] The TWiVome explores induction of antiviral responses by repeating patterns of capsids, and a fungus in the mosquito gut that aids dengue virus replication. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&gt;&lt;/span&gt;&amp;lt;span […] Source link […]



Comment on Trial By Error: A Letter to Archives of Disease in Childhood by ScooterCat86

Sat, 03 Feb 2018 22:00:00 +0000

Thank you to David Tuller and all signatories.



Comment on Trial By Error: My Six-Month Review by Nina

Fri, 02 Feb 2018 17:44:00 +0000

Thank you so much for your hard work, David. It’s appreciated beyond words. I certainly hope you will decide to do another crowdfunding campaign. We need you in our corner! I’m not sure if you are aware of this, but patients in Germany just got an update of their own equivalent of the NICE guidelines. They are absolutely horrific and heavily rely on White et al to promote their deconditioning model. The authors dismissed every biomedical study as “irrelevant” and have displayed a downright contemptuous attitude towards patients and their advocates. One of the groundbreaking additions is the advice for patients to quit smoking. If the tide is changing, it hasn’t reached German shores yet.



Comment on A human rhinovirus in chimpanzees by A human rhinovirus in chimpanzees - VETMEDICS

Fri, 02 Feb 2018 10:59:21 +0000

[…] An outbreak of respiratory disease in Ugandan chimpanzees provides insight into how virus infection can shape the genome and lead to differences in the cell receptor gene that regulate susceptibility to infection. Severe respiratory disease was noted in the Kanyawara community of chimpanzees in western Uganda from February to August of 2013. During this outbreak, […]Source link […]



Comment on A human rhinovirus in chimpanzees by A human rhinovirus in chimpanzees - Virology

Fri, 02 Feb 2018 09:18:55 +0000

[…] An outbreak of respiratory disease in Ugandan chimpanzees provides insight into how virus infection can shape the genome and lead to differences in the cell receptor gene that regulate susceptibility to infection. Severe respiratory disease was noted in the Kanyawara community of chimpanzees in western Uganda from February to August of 2013. During this outbreak, […] Source link […]






Comment on Trial By Error: A Letter to Archives of Disease in Childhood by ixchelkali

Wed, 31 Jan 2018 21:01:00 +0000

I’m so grateful that other scientists are starting to look closely at these papers and are willing to speak out against shoddy science. Some of us patients have spoken out against the smoke-and-mirrors for years, but were dismissed, accused of being militant activists, accused of making vexatious charges, accused of harassing the papers’ authors with the intent of damaging their reputations, and even called names (“chronic fatigue jihadists”). It was like gaslighting on a large scale. It was a frustrating, no-win position, because if we didn’t speak out, the papers would stand unchallenged and if we did speak out, it was used as evidence that we were crazy and shouldn’t be listened to. It’s a relief to have scientists with no dog in the race, except for a belief in scientific integrity, read these papers objectively. I don’t believe that most of us patients are seeking a particular outcome. We just want to arrive at the truth about our disease, with the goal of finding effective treatments. But that can only be achieved by good, solid, well designed, unbiased research. It is frustrating to have the extremely small amount of research funding allocated to this disease wasted on shoddy junk science, which then confounds the results of well conducted research. Thanks so much to Vincent Racaniello, David Tuller, and all who signed the letter for advocating for scientific integrity.



Comment on Trial By Error: A Letter to Archives of Disease in Childhood by Joh

Wed, 31 Jan 2018 20:00:00 +0000

Excellent letter, thank you so much Vincent Racaniello, David Tuller and everybody who signed! <3