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Preview: EurekAlert! - Infectious and Emerging Diseases

EurekAlert! - Infectious and Emerging Diseases



The premier online source for science news since 1996. A service of the American Association for the Advancement of Science.



Last Build Date: Thu, 19 Jan 2017 09:57:01 EST

Copyright: Copyright 2017 American Association for the Advancement of Science (AAAS); All rights reserved.
 



Save the date; 3 months to go until The International Liver CongressTM 2017

Thu, 19 Jan 2017 00:00:00 EST

(European Association for the Study of the Liver) With just over three months to go until The International Liver Congress 2017, we invite you to attend the 52nd Annual Congress of The European Association for the Study of the Liver to be held April 19-23, at the RAI Congress Centre, Amsterdam, The Netherlands.



Blood test can predict life or death outcome for patients with Ebola virus disease

Thu, 19 Jan 2017 00:00:00 EST

(University of Liverpool) Scientists have identified a 'molecular barcode' in the blood of patients with Ebola that can predict whether they are likely to survive or die from the viral infection.A team at the University of Liverpool, in collaboration with Public Health England, Boston University and other international partners, used blood samples taken from infected and recovering patients during the 2013-2016 West Africa outbreak to identify gene products that act as strong predictors of patient outcome.



Case Western Reserve University School of Medicine's Brian Grimberg receives Fulbright award

Wed, 18 Jan 2017 00:00:00 EST

(Case Western Reserve University) Brian T. Grimberg, Ph.D., assistant professor of international health, infectious diseases, and immunology at the Center for Global Health and Diseases at Case Western Reserve University School of Medicine, has received a Fulbright US Scholar Program Award from the US Department of State and the J. William Fulbright Foreign Scholarship Board.



Global partnership launched to prevent epidemics with new vaccines

Wed, 18 Jan 2017 00:00:00 EST

(Wellcome Trust) A global coalition to create new vaccines for emerging infectious diseases, designed to help give the world an insurance policy against epidemics, launches today at the World Economic Forum in Davos, Switzerland.



Special issue highlights research at UM Schools of Medicine and Dentistry

Wed, 18 Jan 2017 00:00:00 EST

(University of Maryland School of Medicine) New research by scientists at the University of Maryland School of Medicine and the University of Maryland School of Dentistry, is highlighted in a special issue of Pathogens and Disease.



Study provides new evidence on role of person-to person transmission in drug-resistant TB

Wed, 18 Jan 2017 00:00:00 EST

(Emory Health Sciences) A study of extensively drug-resistant tuberculosis (XDR TB)in KwaZulu province, South Africa, builds on a growing body of evidence showing person-to-person transmission, not just inadequate treatment, is driving the spread of XDR TB.



NIAID flu experts examine evolution of avian influenza

Wed, 18 Jan 2017 00:00:00 EST

(NIH/National Institute of Allergy and Infectious Diseases) In a new commentary published online in Emerging Infectious Diseases, two leading influenza experts from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, examine how the evolution of proteins found on the surfaces of flu viruses has impacted their ability to infect migratory birds and poultry and cause avian disease.



New dental implant with built-in reservoir reduces risk of infections

Wed, 18 Jan 2017 00:00:00 EST

(KU Leuven) A multidisciplinary team of researchers at KU Leuven has developed a dental implant that gradually releases drugs from a built-in reservoir. This helps prevent and fight infections.



ReSeqTB Data Platform now available to public

Tue, 17 Jan 2017 00:00:00 EST

(The Critical Path Institute (C-Path)) The Rapid Drug Susceptibility Testing Consortium, an arm of the Critcal Path to TB Drug Regimens initiative, announces the public launch of the Relational Sequencing TB Data Platform (ReSeqTB): a user-friendly interface to identify and categorize M.tb mutations associated with drug resistance. Current drug susceptibility tests can take several months. ReSeqTB can change this paradigm by enabling clinicians and researchers to simultaneously identify mutations to all drugs.



NIH scientists identify early impact of Ebola virus on immune system

Tue, 17 Jan 2017 00:00:00 EST

(NIH/National Institute of Allergy and Infectious Diseases) A new mouse model of early Ebola virus (EBOV) infection has shown National Institutes of Health (NIH) scientists and colleagues how early responses of the immune system can affect development of EBOV disease. The model could help identify protective immune responses as targets for developing human EBOV therapeutics.



GeoVax to collaborate with Georgia State on development of hepatitis B therapeutic vaccine

Tue, 17 Jan 2017 00:00:00 EST

(Georgia State University) The Georgia State University Research Foundation has entered into a research collaboration agreement with GeoVax Labs, Inc., a Georgia-based biotechnology company developing human vaccines, to advance development of a therapeutic vaccine for treatment of chronic hepatitis B infections.



Successful antibody trial in HIV-infected individuals

Tue, 17 Jan 2017 00:00:00 EST

(German Center for Infection Research) A research team led by investigators of the Rockefeller University in New York and Prof Florian Klein, University Hospital Cologne and German Center for Infection Research, has tested a new HIV neutralizing antibody, called 10-1074, in humans. The results of the trial have just been published in Nature Medicine.



Penn study identifies potent inhibitor of Zika entry into human cells

Tue, 17 Jan 2017 00:00:00 EST

(University of Pennsylvania School of Medicine) Researchers identified a panel of small molecules that inhibit Zika virus infection, including one that stands out as a potent inhibitor of Zika viral entry into relevant human cell types. They screened a library of 2,000 bioactive compounds for their ability to block Zika virus infection in three distinct cell types using two strains of the virus.



Plant-derived products may help fight HBV

Tue, 17 Jan 2017 00:00:00 EST

(Wiley) Researchers have found that certain plant-derived products may help prevent and treat hepatitis B virus (HBV) infection. Proanthocyanidin (PAC) and its analogs, oolonghomobisflavanes, act by inhibiting viral entry into host cells.



Better diagnosis of fungal infections key to reducing antibiotic resistance

Tue, 17 Jan 2017 00:00:00 EST

(Rutgers University) Poor diagnosis worldwide of fungal disease causes doctors to overprescribe antibiotics, increasing harmful resistance to antimicrobial drugs, according to a paper published today in Emerging Infectious Diseases.



Why hospital antibiotic management strategies do little to curb resistance

Tue, 17 Jan 2017 00:00:00 EST

(Molecular Biology and Evolution (Oxford University Press)) The team have shown that 'determining whether antibiotic cycling or mixing selects best against drug resistant pathogens is not possible, even in standardized questions using mathematical models, let alone in the clinic,' according to lead author Robert Beardmore. Their work may help explain why recent clinical trials like the Saturn project -- explicitly designed to resolved the ongoing issue of high controversy (antibiotic cycling vs. mixing) -- may not work.



Harrington Discovery Institute announces 2017 grant funding to 11 physician-scientists

Mon, 16 Jan 2017 00:00:00 EST

(University Hospitals Cleveland Medical Center) The Harrington Discovery Institute at University Hospitals in Cleveland, Ohio, has announced the 2017 recipients of Harrington Scholar-Innovator Awards. The awards support breakthrough discoveries of physician-scientists whose research shows promise to advance the standard of care.



Researchers found that certain anti-influenza compounds also inhibit Zika virus infection

Mon, 16 Jan 2017 00:00:00 EST

(University of Helsinki) Researchers from the University of Helsinki have shown that three anti-influenza compounds effectively inhibit Zika virus infection in human cells. The results provide the foundation for development of the broad-spectrum cell-directed antivirals or their combinations for treatment of Zika and other emerging viral diseases.



Targets and patented drugs for chemotherapy of Chagas disease

Mon, 16 Jan 2017 00:00:00 EST

(Bentham Science Publishers) Chagas disease is a parasitic infection typically spread by triatomine vectors, affecting millions of people all over Latin America. Existing chemotherapy is centered on benznidazole and nifurtimox, providing unsatisfactory results and substantial side effects. The transmission of the disease by people migration has determined the emergence as a public health problem elsewhere in non-endemic countries of the word. So, the finding of novel ways to challenge this neglected disease is a main priority.



HIV therapy could be contributing to syphilis outbreak: UBC study

Mon, 16 Jan 2017 00:00:00 EST

(University of British Columbia) Drugs used to treat HIV could affect how the body responds to syphilis, inadvertently contributing to a current outbreak, a new study suggests.



UV light can aid hospitals' fight to wipe out drug-resistant superbugs

Mon, 16 Jan 2017 00:00:00 EST

(Duke University Medical Center) A new tool -- a type of ultraviolet light called UVC -- could aid hospitals in the ongoing battle to keep drug-resistant bacteria from lingering in patient rooms and causing new infections.



Viral escape hatch could be treatment target for hepatitis E, Princeton-led study finds

Mon, 16 Jan 2017 00:00:00 EST

(Princeton University) The technique that the hepatitis E virus -- an emerging liver virus historically found in developing countries but now on the rise in Europe -- uses to spread could present a weak spot scientists can exploit to treat the disease, according to a Princeton University-led study.



Intensive animal production may boost flu pandemic threat

Mon, 16 Jan 2017 00:00:00 EST

(University of Exeter) Mass livestock production is driving molecular changes in diseases that could lead to human pandemics, according to an expert from the University of Exeter.



Persistent infection keeps immune memory sharp, leading to long-term protection

Mon, 16 Jan 2017 00:00:00 EST

(Washington University School of Medicine) For many infectious diseases, a single bout of the illness protects a person against contracting it again. Sometimes, the infecting microbe persists in the body long after symptoms resolve. Now, researchers studying the tropical parasite Leishmania have found a clue to explain the link between long-term immunity and long-term infection: The parasite is constantly multiplying and being killed by immune cells, keeping the immune system alert and prepared for any new encounters with the parasite.



How 'stealth warrior' bacteria turn a tick's gut microbes against itself

Mon, 16 Jan 2017 00:00:00 EST

(Yale University) Before infecting humans, tick-borne bacteria or viruses first have to get past a tick's defenses to colonize it. How this occurs is not well understood. To investigate, Yale researchers studied a model of the second-most-common tick-borne infection in the United States, human granulocytic anaplasmosis, which can cause headaches, muscle pain, and even death.