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EurekAlert! - Cancer Research News



The premier online source for science news since 1996. A service of the American Association for the Advancement of Science.



Last Build Date: Wed, 26 Jul 2017 08:54:01 EDT

Copyright: Copyright 2017 American Association for the Advancement of Science (AAAS); All rights reserved.
 



Four young pediatric cancer research fellows earn $1 million in awards

Wed, 26 Jul 2017 00:00:00 EDT

(Damon Runyon Cancer Research Foundation) The Damon Runyon Cancer Research Foundation has named four outstanding young scientists as recipients of the prestigious Damon Runyon-Sohn Pediatric Cancer Fellowship Award, committing nearly $1 million to help address a critical shortage of funding for pediatric cancer research.



Differences in subtypes of gastric cancer may determine prognosis and response to treatment

Wed, 26 Jul 2017 00:00:00 EDT

(American Association for Cancer Research) Molecular classification of the four distinct subtypes of gastric cancer could potentially shape tailored treatment options by helping to predict survival outcomes and patients' response to chemotherapy.



CU Cancer Center study may explain failure of retinoic acid trials against breast cancer

Tue, 25 Jul 2017 00:00:00 EDT

(University of Colorado Anschutz Medical Campus) 'What has been missing in clinical trials may just be the timing of the treatments,' says first author Lynsey Fettig.



Results of NRG-RTOG 0436 highlight need for biomarkers in treatment of esophageal cancer

Tue, 25 Jul 2017 00:00:00 EDT

(NRG Oncology) NRG-RTOG 0436 has determined that adding an epidermal growth factor receptor (EGFR) inhibitor to a chemo-radiation regimen does not improve overall survival for patients with locally advanced esophageal cancer treated in a non-operative manner. These results are reported in 'Effect of the Addition of Cetuximab to Paclitaxel, Cisplatin, and Radiation Therapy for Patients with Esophageal Cancer -- The NRG Oncology RTOG 0436 Phase 3 Randomized Clinical Trial,' which was recently published in the Journal of the American Medical Association Oncology.



Scientists identify gene mutations in smoking-related cancers

Tue, 25 Jul 2017 00:00:00 EDT

(Wake Forest Baptist Medical Center) African-Americans typically have worse outcomes from smoking-related cancers than Caucasians, but the reasons for this remain elusive. However, scientists at Wake Forest Baptist Medical Center have taken a big step toward solving this puzzle.



Physical activity could combat fatigue, cognitive decline in cancer survivors

Tue, 25 Jul 2017 00:00:00 EDT

(University of Illinois at Urbana-Champaign) A new study indicates that cancer patients and survivors have a ready weapon against fatigue and 'chemo brain': a brisk walk. Researchers at the University of Illinois, along with collaborators at Digital Artefacts in Iowa City, Iowa, and Northeastern University in Boston, looked at the association between physical activity, fatigue and performance on cognitive tasks in nearly 300 breast cancer survivors.



Elevated cholesterol's link with canine cancer includes a better prognosis

Tue, 25 Jul 2017 00:00:00 EDT

(Oregon State University) Usually thought of as a health detriment, elevated cholesterol may play a role in longer survival times for dogs with a common form of bone cancer.



Americans say discussions about clinical trials should be part of standard of care

Tue, 25 Jul 2017 00:00:00 EDT

(Research!America) An overwhelming majority of Americans (86%) agree that health care professionals should discuss clinical trials with patients diagnosed with a disease as part of their standard of care, according to a new national public opinion survey commissioned by Research!America. And three-quarters of respondents (75%) agree that taking part in clinical trials is as valuable to our health care system as giving blood.



New discovery could reverse tissue damage caused by heart attacks

Tue, 25 Jul 2017 00:00:00 EDT

(University of Bristol) A new discovery by University of Bristol scientists helps to explain how cells which surround blood vessels, called pericytes, stimulate new blood vessels to grow with the hormone 'leptin' playing a key role. Leptin is produced by fat cells which helps to regulate energy balance in the body by inhibiting the appetite. This study, described in Scientific Reports, may have important implications for the treatment of heart attacks and also for cancer, the two main killers in the UK.



Nanoparticles loaded with component of common spice kill cancer cells

Tue, 25 Jul 2017 00:00:00 EDT

(University of Central Florida) Attaching curcumin, a component of the common spice turmeric, to nanoparticles can be used to target and destroy treatment-resistant neuroblastoma tumor cells, according to a new study published in Nanoscale. The study, conducted in partnership by researchers at Nemours Children's Hospital and the University of Central Florida, demonstrates a potentially novel treatment for neuroblastoma, the most common cancer in infants.



Shedding light on cause of resistance to tumor immunotherapy

Tue, 25 Jul 2017 00:00:00 EDT

(University of Zurich) In tumor immunotherapy, the body's own defense system is activated against the tumor cells. However, for the majority of patients, the tumor cells become resistant to the treatments used. Researchers at the University of Zurich and the University Hospital Zurich have now found in skin cutaneous melanoma that an epigenetic control protein is key to the development of this resistance.



Possible treatment for deadly weight loss

Tue, 25 Jul 2017 00:00:00 EDT

(Norwegian University of Science and Technology) Many cancer patients are susceptible to potentially lethal weight loss. Now researchers understand better why this happens, and perhaps how to prevent the condition.



Reaching black men in barbershops could lead to early detection of colorectal cancer

Mon, 24 Jul 2017 00:00:00 EDT

(NYU Langone Health / NYU School of Medicine) NYU Langone researchers find that black men who enrolled in a patient navigator program at local barbershops were twice as likely to get colorectal cancer screening.



NCI-COG Pediatric MATCH trial to test targeted drugs in childhood cancers

Mon, 24 Jul 2017 00:00:00 EDT

(NIH/National Cancer Institute) Investigators at the National Cancer Institute and the Children's Oncology Group announce the opening of enrollment for NCI-COG Pediatric MATCH, a unique precision medicine clinical trial to explore whether targeted therapies can be effective for children and adolescents with solid tumors that harbor specific genetic mutations and have progressed during or after standard therapy.



Rahul Roychoudhuri awarded prestigious Lister Prize

Mon, 24 Jul 2017 00:00:00 EDT

(Babraham Institute) The Lister Institute of Preventive Medicine has selected Dr Rahul Roychoudhuri, to receive a Research Prize Fellowship. The prize aims to 'make a real difference' by supporting outstanding young independent researchers. Fellowships are presented annually and Fellows often go on to be leaders in their fields. Roychoudhuri joined the Babraham Institute in 2015, investigating immune system regulation. His work impacts people with autoimmune diseases, severe allergies and some cancers.



Breast cancer patients can use antiperspirants during radiotherapy

Mon, 24 Jul 2017 00:00:00 EDT

(University of Pennsylvania School of Medicine) Women undergoing daily radiation therapy for breast cancer are commonly told they should not use antiperspirant for fear that it could cause greater radiation damage to the skin, but a new study from the Perelman School of Medicine at the University of Pennsylvania showed there was no difference in the radiation skin dose absorbed by these patients with or without these deodorants.



Georgia State's Inlighta Biosciences gets $2 million grant to develop enhanced MRI contrast agents

Mon, 24 Jul 2017 00:00:00 EDT

(Georgia State University) A local start-up, life sciences company founded by Dr. Jenny Yang, Regents' Professor of Biochemistry at Georgia State University, has received a $2 million federal grant to develop improved magnetic resonance imaging (MRI) contrast agents for the early detection of liver cancers and other cancers, such as uveal melanoma or eye cancer, that have metastasized to the liver.



Neuroticism may postpone death for some

Mon, 24 Jul 2017 00:00:00 EDT

(Association for Psychological Science) Data from a longitudinal study of over 500,000 people in the United Kingdom indicate that having higher levels of the personality trait neuroticism may reduce the risk of death for individuals who report being in fair or poor health. The research, published in Psychological Science, a journal of the Association for Psychological Science, further revealed that a specific aspect of neuroticism related to worry and feelings of vulnerability was associated with lower mortality, regardless of self-reported health.



Immune cells the missing ingredient in new bladder cancer treatment

Mon, 24 Jul 2017 00:00:00 EDT

(University of British Columbia) New research offers a possible explanation for why a new type of cancer treatment hasn't been working as expected against bladder cancer.



New therapeutic approach for difficult-to-treat subtype of ovarian cancer identified

Mon, 24 Jul 2017 00:00:00 EDT

(The Wistar Institute) A potential new therapeutic strategy for a difficult-to-treat form of ovarian cancer has been discovered by Wistar scientists. The findings were published online in Nature Cell Biology.



Molecular hitchhiker on human protein signals tumors to self-destruct

Mon, 24 Jul 2017 00:00:00 EDT

(Vanderbilt University) Vanderbilt University engineers find existing human protein is ideal carrier for powerful molecules that can signal tumors to self-destruct.



Weight in adolescence may affect colorectal cancer risk

Mon, 24 Jul 2017 00:00:00 EDT

(Wiley) A new study has uncovered a link between being overweight or obese in adolescence and an increased risk of developing colon cancer in adulthood.



Anti-cancer chemotherapeutic agent inhibits glioblastoma growth and radiation resistance

Mon, 24 Jul 2017 00:00:00 EDT

(University of Alabama at Birmingham) A collaborative team of neuro-oncology surgeon/scientists -- led by Ichiro Nakano, M.D., Ph.D., University of Alabama at Birmingham, and Maode Wang, M.D., Xi'an Jiaotong University, Xi'an, China -- has discovered a unique and previously unidentified molecular mechanism that maintains glioma stem cells, and they have tested it as a potential therapeutic target in glioblastoma, using a novel small molecule inhibitor they designed and synthesized



Researchers develop new method to generate human antibodies

Mon, 24 Jul 2017 00:00:00 EDT

(Rockefeller University Press) An international team of scientists has developed a method to rapidly produce specific human antibodies in the laboratory. The technique, which will be described in a paper to be published July 24 in the Journal of Experimental Medicine, could speed the production of antibodies to treat a wide range of diseases and facilitate the development of new vaccines.



Offer of $100 boosts rates of colon cancer screenings

Fri, 21 Jul 2017 00:00:00 EDT

(University of Pennsylvania School of Medicine) Offering $100 to patients eligible for a preventive colonoscopy screening more than doubled the rate of screening when compared to a simple emailed request, according to new research from the Perelman School of Medicine at the University of Pennsylvania.