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EurekAlert! - Cancer Research News



The premier online source for science news since 1996. A service of the American Association for the Advancement of Science.



Last Build Date: Fri, 09 Sep 2016 02:54:01 EDT

Copyright: Copyright 2016 American Association for the Advancement of Science (AAAS); All rights reserved.
 



New insights into tumor-infiltrating T cells

Thu, 08 Sep 2016 00:00:00 EDT

(Brigham and Women's Hospital) Investigators from Brigham and Women's Hospital have identified a distinct gene module for T cell dysfunction distinct from activation in tumor-infiltrating T cells, thus paving the way for the development of new precision therapeutics.



AMP to recognize Eric Lander with 2016 Award for Excellence in Molecular Diagnostics

Thu, 08 Sep 2016 00:00:00 EDT

(Association for Molecular Pathology) Eric Lander, Ph.D., has earned this year's Association for Molecular Pathology (AMP) Award for Excellence in Molecular Diagnostics for his countless contributions to the field. The award will be presented at the AMP 2016 Annual Meeting. Following the award presentation, Dr. Lander will deliver a special lecture on his 35-year journey uncovering insights to benefit human health.



Three in 4 don't know obesity causes cancer

Thu, 08 Sep 2016 00:00:00 EDT

(Cancer Research UK) Three out of four (75 percent) people in the UK are unaware of the link between obesity and cancer, according to a new Cancer Research UK report published today.



Study shows how Chinese medicine kills cancer cells

Thu, 08 Sep 2016 00:00:00 EDT

(University of Adelaide) Researchers at the University of Adelaide have shown how a complex mix of plant compounds derived from ancient clinical practice in China -- a Traditional Chinese Medicine -- works to kill cancer cells.



ERC Starting Grants: €485 million in grants to 325 top researchers across Europe

Thu, 08 Sep 2016 00:00:00 EDT

(European Research Council) The European Research Council (ERC) has announced today the awarding of its Starting Grants to 325 early-career researchers throughout Europe. The funding, worth in total €485 million and up to €1.5 million per grant, will enable them to set up their own research teams and pursue ground-breaking ideas.



Tamoxifen resistance linked to high estrogen levels in utero

Thu, 08 Sep 2016 00:00:00 EDT

(Georgetown University Medical Center) An animal study suggests that resistance to tamoxifen therapy in some estrogen receptor positive breast cancers may originate from in utero exposure to endocrine disrupting chemicals. The study provides a new path forward in human research as about half of the breast cancers treated with this common cancer therapy do not respond well, say researchers at the Georgetown Lombardi Comprehensive Cancer Center, who led the multi-institutional research.



Chronic Sinusitis Associated With Certain Rare Head and Neck Cancers among Elderly, Although AbsoluChronic sinusitis associated with certain rare head and neck cancers among elderly, although absolut

Thu, 08 Sep 2016 00:00:00 EDT

(The JAMA Network Journals) In a study published online by JAMA Otolaryngology-Head & Neck Surgery, Daniel C. Beachler, Ph.D., M.H.S., and Eric A. Engels, M.D., M.P.H., of the National Cancer Institute, Bethesda, Md., evaluated the associations of chronic sinusitis with subsequent head and neck cancer in an elderly population.



After long-term follow-up, study looks at prognostic factors for breast cancer

Thu, 08 Sep 2016 00:00:00 EDT

(The JAMA Network Journals) A new study published online by JAMA Oncology is long-term analysis of prognostic factors among some patients with breast cancer who were treated with breast-conserving therapy in the EORTC 'boost no boost' trial, which evaluated the influence of a 'boost' dose in radiotherapy.



Cancer cells metastasize by hitching a ride on platelets

Thu, 08 Sep 2016 00:00:00 EDT

(JCI Journals) In this issue of JCI Insight, Pierre Henri Mangin and colleagues at the Etablissement Français du Sang-Alsace have shown that a molecule expressed on platelets, known as α6β1 integrin, participates in tumor metastasis by promoting interactions between tumor cells and platelets.



Patients with advanced lymphoma in remission after T-cell therapy

Wed, 07 Sep 2016 00:00:00 EDT

(Fred Hutchinson Cancer Research Center) In a paper published today in Science Translational Medicine, researchers from Fred Hutchinson Cancer Research Center shared data from an early-phase study of patients with advanced non-Hodgkin lymphoma (NHL) who received JCAR014, a Chimeric Antigen Receptor (CAR) T cell treatment, and chemotherapy. CAR T cells are made from a patient's own immune cells that are then genetically engineered to better identify and kill cancer cells.



10 Cancer Moonshot Blue Ribbon Panel recommendations embraced by NCI

Wed, 07 Sep 2016 00:00:00 EDT

(University of California - San Diego) When 28 distinguished individuals convened earlier this year to help shape the scientific mission at the National Cancer Institute (NCI) of Vice President Joe Biden's National Cancer Moonshot Initiative, they were given five months to draft guidelines to accelerate cancer research, prevention and care. On Wednesday, the National Cancer Advisory Board approved the Blue Ribbon Panel's 10 recommendations.



Researchers find molecular link behind aspirin's protective powers

Wed, 07 Sep 2016 00:00:00 EDT

(Duke University Medical Center) Researchers at Duke Health have identified a new mechanism of aspirin's action that appears to explain the drug's diverse benefits.



Experimental drug could stop melanoma, other cancers, research suggests

Wed, 07 Sep 2016 00:00:00 EDT

(University of Virginia Health System) An experimental cancer drug works differently than intended and shows significant promise for stopping melanoma and possibly other forms of cancer.



RIT and Rochester Regional Health collaborate to improve breast cancer screening

Wed, 07 Sep 2016 00:00:00 EDT

(Rochester Institute of Technology) Researchers at Rochester Institute of Technology and physicians at Rochester Regional Health are advancing thermal imaging techniques as a potentially safer and less invasive diagnostic tool for the detection of early-stage breast cancer. A National Science Foundation grant of $99,620 is supporting the two-year project.



Fruit flies yield clues on cancerous tumor hotspots

Wed, 07 Sep 2016 00:00:00 EDT

(Florida State University) A Florida State University research team, in coordination with a team from Japan, has found that the epithelial tissues that line the surfaces of organs throughout the body intrinsically have hot spots for cancerous tumors.They discovered this by examining a common household pest -- the fruit fly.



Scientists identify genes that disrupt response to breast cancer treatment

Wed, 07 Sep 2016 00:00:00 EDT

(University of Illinois at Urbana-Champaign) In breakthrough research on breast cancer, a team at the University of Illinois discovered that higher levels of the nuclear transport gene XPO1 indicate when a patient is likely to be resistant to the popular drug tamoxifen. The team is led by food science and human nutrition professor Zeynep Madak-Erdogan.



Northeastern partners with leading immunologist to uncover protein linked to cancer

Wed, 07 Sep 2016 00:00:00 EDT

(Northeastern University College of Science) In a recently funded project involving Boston Children's Hospital and Northeastern University, chemistry Professors John R. Engen and Roxana Iacob have teamed up with Prof. Timothy A. Springer -- a renowned immunologist and structural biologist from Harvard Medical School and Boston Children's Hospital -- to uncover the inner workings of an extremely complex class of proteins.



Ginger and chili peppers could work together to lower cancer risk

Wed, 07 Sep 2016 00:00:00 EDT

(American Chemical Society) For many people, there's nothing more satisfying than a hot, spicy meal. But some research has suggested that capsaicin, the compound that gives chili peppers their kick, might cause cancer. Now researchers show in mouse studies that the pungent compound in ginger, 6-ginergol, could counteract capsaicin's potentially harmful effects. In combination with the capsaicin, 6-gingerol could lower the risk of cancer, they say. The study appears in ACS' Journal of Agricultural and Food Chemistry.



Sugar transforms a traditional Chinese medicine into a cruise missile

Wed, 07 Sep 2016 00:00:00 EDT

(Johns Hopkins Medicine) A chemical biologist and his colleagues at the Johns Hopkins University School of Medicine report that tests of triptolide in human cells and mice are vastly improved by the chemical attachment of glucose to the triptolide molecule.



LSU Health dentistry grant to help improve oral cancer survival

Wed, 07 Sep 2016 00:00:00 EDT

(Louisiana State University Health Sciences Center) Dr. Kitrina Cordell, Associate Professor and Head of the Department of Diagnostic Sciences at LSU Health New Orleans School of Dentistry, has been awarded a grant by the Academy of General Dentistry to develop a school-wide program to teach patients about self oral cancer screening. The majority of patients are not familiar with signs and symptoms associated with precancerous changes and oral cancers, and early detection saves lives.



Computerized tissue image analysis reveals underlying genomics of ER+ breast cancer

Wed, 07 Sep 2016 00:00:00 EDT

(Case Western Reserve University) The number of tubules in tumors may predict which women with estrogen receptor positive (ER+) breast cancer will benefit from hormone therapy alone and which require chemotherapy. A computer program to automatically count the tubules correlated with the scores produced by the current best test differentiating between indolent and aggressive ER+ cancers.



A new way of taming ions can improve future health care

Wed, 07 Sep 2016 00:00:00 EDT

(Chalmers University of Technology) A group of researchers at Chalmers University of Technology has discovered a completely new way of using lasers to accelerate ion beams. In time, the new technique could possibly give more people access to advanced cancer treatment. The results were recently published in the high impact journal Physical Review Letters.



Aberrant epigenetic regulation behind the intestinal symptoms in celiac disease

Wed, 07 Sep 2016 00:00:00 EDT

(Academy of Finland) Researchers at the University of Tampere discovered a regulation mechanism governing the intestinal homeostasis. Disturbances in this mechanism are implicated in celiac disease and possibly also in colorectal cancer.



Physical activity may offset some of alcohol's lethal harms

Wed, 07 Sep 2016 00:00:00 EDT

(University of Sydney) An international research collaboration, led by University of Sydney, has found that exercising at even basic recommended weekly physical activity levels (at least 150 minutes of moderate-intensity activity) may offset some of the harmful effects of drinking alcohol. Published today in the British Journal of Sports Medicine, this first-of-its-kind study found that for alcohol drinkers, physical activity may decrease the risks of dying both from cancer and from 'all-cause mortality' that is, deaths from any cause.



New tumor analysis method identifies high-risk prostate cancer

Wed, 07 Sep 2016 00:00:00 EDT

(Cedars-Sinai Medical Center) Scientists at Cedars-Sinai have developed a new way to identify which prostate cancer patients are likely to develop aggressive types of the disease even if their tumors at first appear to be lower risk. The new findings could help physicians prescribe the most effective treatments for each patient based on how genes are activated in the individual tumor.