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EurekAlert! - Cancer Research News



The premier online source for science news since 1996. A service of the American Association for the Advancement of Science.



Last Build Date: Tue, 28 Feb 2017 07:54:01 EST

Copyright: Copyright 2017 American Association for the Advancement of Science (AAAS); All rights reserved.
 



Researchers discover how breast cancer mutation in BRCA1 causes protein to self-destruct

Tue, 28 Feb 2017 00:00:00 EST

(Virginia Tech) Scientists at the Virginia Tech Carilion Research Institute found that breast cancer cells can trigger the self-destruction of the tumor-suppressing BRCA1 proteins.



Tanning devices cost US healthcare $343 million a year

Tue, 28 Feb 2017 00:00:00 EST

(Elsevier) Tanning devices cost the US $343.1 million a year in medical costs because of the skin cancers their use is associated with, according to a new study published in the Journal of Cancer Policy. In a new study, Dr. Hugh Waters and his colleagues from the University of North Carolina established how prevalent indoor tanning-related skin cancers are in the US, and calculated the costs of these diseases.



Mammography trends show improved cancer detection, more biopsies

Tue, 28 Feb 2017 00:00:00 EST

(Radiological Society of North America) The shift from film to digital technology appears to have improved cancer detection rates for diagnostic mammography, but also has increased the abnormal interpretation rate, which may lead to more women undergoing biopsies for benign conditions, according to a new study.



Hitgen and Cancer Research UK's Manchester Institute enter licence agreement in lung cancer

Mon, 27 Feb 2017 00:00:00 EST

(Cancer Research UK) CANCER RESEARCH UK, Cancer Research Technology (CRT), the charity's commercial arm, and HitGen Ltd, a privately held biotech company focused on early drug discovery, announced today that they have entered into a licence agreement to develop a novel class of drugs against lung cancer.



Matching up fruit flies, mushroom toxins and human health

Mon, 27 Feb 2017 00:00:00 EST

(Michigan Technological University) Some fruit flies build up tolerance to the toxin alpha-amanitin; the genetic mechanisms behind this adaptation link to an important metabolic pathway. A team from Michigan Technological University used genome-wide association mapping to draw the connections for 180 fruit fly lines.



Molecule stops fatal pediatric brain tumor

Mon, 27 Feb 2017 00:00:00 EST

(Northwestern University) Northwestern Medicine scientists have found a molecule that stops the growth of an aggressive pediatric brain tumor. The tumor is always fatal and primarily strikes children under 10 years old. Every other attempted therapy has failed.



Frequent, personalized CA125 testing may help detect ovarian cancer in high-risk women

Mon, 27 Feb 2017 00:00:00 EST

(Massachusetts General Hospital) The combined results of two ovarian cancer screening trials suggest that a personalized strategy involving frequent screening of high-risk women could improve the chance that tumors are detected at early stages when they are easier to treat.



Who gets sunburned? Survey finds risk is greater for young adults with melanin-rich skin

Mon, 27 Feb 2017 00:00:00 EST

(American Osteopathic Association) Results from a study published in The Journal of the American Osteopathic Association point to an urgent need for sunburn prevention among young adults, particularly those who have skin with higher melanin content. Researchers found a surprising correlation between reporting a red or painful sunburn lasting a day or more with being 18 to 29 years of age and not self-identifying as white.



Super resolution imaging helps determine a stem cell's future

Mon, 27 Feb 2017 00:00:00 EST

(Rutgers University) Scientists at Rutgers and other universities have created a new way to identify the state and fate of stem cells earlier than previously possible. Understanding a stem cell's fate -- the type of cell it will eventually become -- and how far along it is in the process of development can help scientists better manipulate cells for stem cell therapy.



Largest study of factors affecting African-Americans with cancer announced in Detroit

Mon, 27 Feb 2017 00:00:00 EST

(Wayne State University - Office of the Vice President for Research) The Karmanos Cancer Institute and Wayne State University School of Medicine will launch the nation's largest study of African-American cancer survivors to better understand disproportionately high incidence and mortality from cancer and its impact on this specific patient population.



Genetic variant of p53 gene linked to breast cancer risk in premenopausal African American women

Mon, 27 Feb 2017 00:00:00 EST

(The Wistar Institute) Scientists at The Wistar Institute in collaboration with Roswell Park Cancer Institute found a significant association between a rare genetic variant of the p53 gene present in African American women and their risk of developing breast cancer in premenopausal age.



Statins do not benefit patients with lung cancer, new study shows

Mon, 27 Feb 2017 00:00:00 EST

(Imperial College London) Cholesterol-lowering drugs used alongside chemotherapy have no effect on treatment outcomes for lung cancer patients, according to a new study.



Study finds biomarker for lung cancer detection in the nasal passages of smokers

Mon, 27 Feb 2017 00:00:00 EST

(Boston University Medical Center) A new nasal test may allow patients suspected of having lung cancer to undergo a simple swab of their nose to determine if they have the disease. Researchers at Boston University School of Medicine (BUSM) have found that a genomic biomarker in the nasal passage can accurately determine the likelihood of a lung lesion being malignant.



Molecular 'on switch' could point to treatments for pediatric brain tumor

Fri, 24 Feb 2017 00:00:00 EST

(Massachusetts General Hospital) Massachusetts General Hospital researchers have identified a mechanism that controls the expression of genes regulating the growth of the most aggressive form of medulloblastoma, the most common pediatric brain tumor.



New structural studies reveal workings of a molecular pump that ejects cancer drugs

Fri, 24 Feb 2017 00:00:00 EST

(Rockefeller University) Sometimes cells spit out things we don't want them to -- like medications. Researchers have determined the three-dimensional structure of a tiny pump that expels, among other things, chemotherapy agents. This new knowledge could lead to the design of more effective drugs.



New antiviral drug cuts cytomegalovirus infection and improves survival in patients

Fri, 24 Feb 2017 00:00:00 EST

(Dana-Farber Cancer Institute) In a significant advance in improving the safety of donor stem cell transplants, a major clinical trial led by researchers at Dana-Farber Cancer Institute has shown that a novel agent can protect against the most common viral infection that patients face after transplantation.



A novel DNA vaccine design improves chances of inducing anti-tumor immunity

Fri, 24 Feb 2017 00:00:00 EST

(The Wistar Institute) Scientists at The Wistar Institute and Inovio Pharmaceuticals, Inc. have devised a novel DNA vaccine approach through molecular design to improve the immune responses elicited against one of the most important cancer antigen targets.



Tissue-engineered model developed to study bone-invading tumor

Fri, 24 Feb 2017 00:00:00 EST

(Mary Ann Liebert, Inc./Genetic Engineering News) Researchers have used tissue engineering to create models for studying the bone-destroying activity of tumors such as the aggressive pediatric cancer Ewing's sarcoma.



The potential consequences for cancer care and cancer research of Brexit

Fri, 24 Feb 2017 00:00:00 EST

(ecancermedicalscience) Cancer leaders highlight main fears for patient care, treatment and research in a post-Brexit world.



Novel 'barcode' tracking of T cells in immunotherapy patients identifies likely cancer-

Fri, 24 Feb 2017 00:00:00 EST

(Fred Hutchinson Cancer Research Center) A new discovery by researchers at the Fred Hutchinson Cancer Research Center in Seattle makes an important step in identifying which specific T cells within the diverse army of a person's immune system are best suited to fight cancer.The findings will be published Feb. 24 in Science Immunology.



Nicotinamide riboside (vitamin B3) prevents nerve pain caused by cancer drugs

Thu, 23 Feb 2017 00:00:00 EST

(University of Iowa Health Care) A new study in rats suggests that nicotinamide riboside (NR), a form of vitamin B3, may be useful for treating or preventing nerve pain (neuropathy) caused by chemotherapy drugs. The findings by researchers at the University of Iowa were published recently in the Journal of the International Association for the Study of Pain (PAIN) and lay the groundwork for testing whether this nutritional supplement can reduce nerve pain in cancer patients receiving chemotherapy.



Boston researcher receives global surgery award

Thu, 23 Feb 2017 00:00:00 EST

(Boston University Medical Center) Maunil Bhatt, M.D., a post graduate resident in the Department of Surgery at Boston University School of Medicine and Boston Medical Center (BMC), was recently honored with a Global Surgery Research Fellowship Award by the Association for Academic Surgery (AAS) at their 12th Annual Academic Conference.



Gene mutations cause leukemia, but which ones?

Thu, 23 Feb 2017 00:00:00 EST

(Oregon Health & Science University) Watanabe-Smith's research, published today in the journal Oncotarget, sought to better understand one 'typo' in a standard leukemia assay, or test. While studying cancer biology and completing his doctorate in the lab of Brian Druker, M.D., at the OHSU Knight Cancer Institute, Watanabe-Smith encountered a new problem: an issue with the model system itself.



New gene sequencing software could aid in early detection, treatment of cancer

Thu, 23 Feb 2017 00:00:00 EST

(Johns Hopkins University) A research team from the United States and Canada has developed and successfully tested new computational software that determines whether a human DNA sample includes an epigenetic add-on linked to cancer and other adverse health conditions.



Researchers uncover a role for HSP90 in gene-environment interactions in humans

Thu, 23 Feb 2017 00:00:00 EST

(Whitehead Institute for Biomedical Research) Researchers at the Whitehead Institute have now uncovered a role for the protein-folding chaperone HSP90 in humans, not only as a modifier of the effects of mutations, but as a mediator of the impact of the environment on the function of mutant proteins. And these effects of HSP90 can alter the course of human diseases.