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EurekAlert! - Cancer Research News



The premier online source for science news since 1996. A service of the American Association for the Advancement of Science.



Last Build Date: Sun, 25 Jun 2017 02:54:01 EDT

Copyright: Copyright 2017 American Association for the Advancement of Science (AAAS); All rights reserved.
 



Targeted drug shows promise in rare advanced kidney cancer

Fri, 23 Jun 2017 00:00:00 EDT

(Dana-Farber Cancer Institute) Some patients with a form of advanced kidney cancer benefited from an experimental drug targeted to an abnormal genetic pathway causing cancerous growth, according to research led by Dana-Farber Cancer Institute scientists.



More breast cancers were diagnosed at early stage after Affordable Care Act took effect

Fri, 23 Jun 2017 00:00:00 EDT

(Loyola University Health System) A Loyola University Chicago study published this month has found an increase in the percentage of breast cancer patients who were diagnosed in early Stage 1, after the Affordable Care Act took effect. The increases in Stage 1 diagnoses were higher among African American and Latina breast cancer patients, compared to white patients.



MRI without contrast agents? Yes, with sugar!

Fri, 23 Jun 2017 00:00:00 EDT

(German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)) Scientists from the German Cancer Research Center (DKFZ), in collaboration with colleagues from Heidelberg University Hospital, have been able to visualize brain cancer using a novel MRI method. They use a simple sugar solution instead of conventional contrast agents, which can have side effects in the body.



A unique amino acid for brain cancer therapy

Fri, 23 Jun 2017 00:00:00 EDT

(Okinawa Institute of Science and Technology (OIST) Graduate University) Researchers discover potential application of amino acid taurine in photodynamic therapy for brain cancer.



Immunotherapy kinder than chemotherapy for patients with head and neck cancer

Fri, 23 Jun 2017 00:00:00 EDT

(Institute of Cancer Research) The immunotherapy nivolumab is kinder than chemotherapy for people with advanced head and neck cancer -- easing many of the negative effects of the disease on patients' quality of life.



Existing drugs could benefit patients with bone cancer, genetic study suggests

Fri, 23 Jun 2017 00:00:00 EDT

(Wellcome Trust Sanger Institute) A subgroup of patients with osteosarcoma -- a form of bone cancer -- could be helped by an existing drug, suggest scientists from the Wellcome Trust Sanger Institute and their collaborators. In the largest genetic sequencing study of osteosarcoma to date, scientists discovered that 10 percent of patients with a genetic mutation in particular growth factor signalling genes may benefit from existing drugs, known as IGF1R inhibitors.



Discovery of a new mechanism involved in the migration of cancer cells

Thu, 22 Jun 2017 00:00:00 EDT

(Comprehensive Cancer Centre Gustave Roussy) A team of young French researchers has discovered a new mechanism which facilitates cell migration. On the surface of its membrane, the cell develops multiple small hooks which help it to attach to fibers outside the cell and move along them. This action helps us to understand better how a cell escapes from the tumor mass and moves around the body to form a new focus.



Combined molecular biology test is the first to distinguish benign pancreatic lesions

Thu, 22 Jun 2017 00:00:00 EDT

(American College of Surgeons) When performed in tandem, two molecular biology laboratory tests distinguish, with near certainty, pancreatic lesions that mimic early signs of cancer but are completely benign. The lesions almost never progress to cancer, so patients may be spared unnecessary pancreatic cancer screenings or operations. The two-test combination is the only one to date that can accurately and specifically identify these benign pancreatic lesions.



New biomarker assay detects neuroblastoma with greater sensitivity

Thu, 22 Jun 2017 00:00:00 EDT

(Children's Hospital Los Angeles) Investigators at The Saban Research Institute of Children's Hospital Los Angeles have developed and tested a new biomarker assay for quantifying disease and detecting the presence of neuroblastoma even when standard evaluations yield negative results for the disease. Researchers provide the first systematic comparison of standard imaging evaluations versus the new assay that screens for five different neuroblastoma-associated genes and determine that the new assay improves disease assessment and provides prediction of disease progression.



Tiny nanoparticles offer significant potential in detecting/treating disease new review of work on exosomes

Thu, 22 Jun 2017 00:00:00 EDT

(Swansea University) Exosomes - tiny biological nanoparticles which transfer information between cells - offer significant potential in detecting and treating disease, the most comprehensive overview so far of research in the field has concluded. Areas which could benefit include cancer treatment and regenerative medicine.



Georgia State hosts first International Triple Negative Breast Cancer Conference

Thu, 22 Jun 2017 00:00:00 EDT

(Georgia State University) Georgia State University will host the First International Triple Negative Breast Cancer Conference from Sept. 18 to 20.



Custom built molecule shows promise as anti-cancer therapy

Thu, 22 Jun 2017 00:00:00 EDT

(University of Bath) Scientists at the University of Bath funded by Cancer Research UK have custom-built a molecule which stops breast cancer cells from multiplying in laboratory trials, and hope it will eventually lead to a treatment for the disease.



Does MRI plus mammography improve detection of new breast cancer after breast conservation therapy?

Thu, 22 Jun 2017 00:00:00 EDT

(The JAMA Network Journals) A new article published by JAMA Oncology compares outcomes for combined mammography and MRI or ultrasonography screenings for new breast cancers in women who have previously undergone breast conservation surgery and radiotherapy for breast cancer initially diagnosed at 50 or younger.



HPV testing leads to earlier detection and treatment of cervical pre-cancer

Thu, 22 Jun 2017 00:00:00 EDT

(Queen Mary University of London) Women who receive human papillomavirus (HPV) testing, in addition to a pap smear, receive a faster, more complete diagnosis of possible cervical precancer, according to a study of over 450,000 women by Queen Mary University of London (QMUL) and the University of New Mexico (UNM) Comprehensive Cancer Center.



Researchers find way to better use current drugs to target cancer

Thu, 22 Jun 2017 00:00:00 EDT

(McMaster University) The drugs helped to understand the biology. The researchers worked backwards, employing a series of drugs used in the clinic to understand a new way that cancer stem cells can be killed.



Cleveland Clinic discovers similarities between next-generation prostate cancer drugs

Thu, 22 Jun 2017 00:00:00 EDT

(Cleveland Clinic) Cleveland Clinic researchers have shown for the first time how a class of advanced prostate cancer drugs are processed in the body and how their anti-tumor activity might change depending on how they are metabolized. Their pre-clinical findings, just published in Cell Chemical Biology, may lay the foundation for improving therapies for treatment-resistant, aggressive prostate cancer.



Secondhand smoke exposure among nonsmoking adult cancer survivors has declined

Thu, 22 Jun 2017 00:00:00 EDT

(American Association for Cancer Research) From 1999/2000 to 2011/2012, exposure to secondhand smoke among nonsmoking adult cancer survivors declined from 39.6 percent to 15.7 percent, but rates of exposure were higher among those with a history of a smoking-related cancer and those living below the federal poverty level compared with those with other types of cancer and those with the highest incomes, respectively.



Localized signaling islands in cells: New targets for precision drug design

Thu, 22 Jun 2017 00:00:00 EDT

(University of Washington Health Sciences/UW Medicine) New research overturns long-held views on a basic messaging system within living cells. Key cellular communication machinery is more regionally constrained within the cell than previously thought. The findings suggest new approaches to designing precision drugs. Localizing drug action at a specific 'address' within the cell could mean fewer side effects in treating cancer, diabetes, heart disease and other serious conditions.



Scientists uncover potential mechanism for HPV-induced skin cancer

Thu, 22 Jun 2017 00:00:00 EDT

(PLOS) Scientists have identified a molecular pathway by which some types of human papilloma virus (HPV) might increase the risk of skin cancer, particularly in people with the rare genetic disorder epidermodysplasia verruciformis (EV). The novel pathway is described in PLOS Pathogens.



New femto-camera with quadrillion fractions of a second resolution

Wed, 21 Jun 2017 00:00:00 EDT

(ITMO University) Researchers from ITMO University have built a setup for recording holograms of tiny objects like living cells with a femtosecond speed. The new method allows one to reconstruct phase topography of a studied sample according to deformations that emerge in a laser pulse when it passes through the specimen. In comparison to electron microscopes, the device can visualize transparent biological structures without introducing contrast agents. The paper was published in Applied Physics Letters.



Analysis indicates that insurance expansion improves access to care, health, and survival

Wed, 21 Jun 2017 00:00:00 EDT

(Harvard T.H. Chan School of Public Health) There is strong evidence that expanding health insurance increases access to care, improves health in a variety of ways, and reduces mortality, according to Harvard T.H. Chan School of Public Health researchers,



The (extra) eyes have it

Wed, 21 Jun 2017 00:00:00 EDT

(University of California - Santa Barbara) Your doctor is an expert with many years of experience. So when she tells you, upon reviewing all the fancy tomographic imaging you had done, that the tenderness in your breast is just some minor irritation, you want to believe her and leave it at that.



Underused cancer test could improve treatment for thousands

Wed, 21 Jun 2017 00:00:00 EDT

(Mayo Clinic) A simple blood test could improve treatment for more than 1 in 6 stage 2 colon cancer patients, suggests new Mayo Clinic research. The researchers also discovered that many patients who could benefit from the test likely aren't receiving it. The findings were published in the Journal of Gastrointestinal Surgery.



New inhibitor drug shows promise in relapsed leukemia

Wed, 21 Jun 2017 00:00:00 EDT

(University of Pennsylvania School of Medicine) A new drug shows promise in its ability to target one of the most common and sinister mutations of acute myeloid leukemia (AML), according to researchers at the Perelman School of Medicine at the University of Pennsylvania and Penn's Abramson Cancer Center. In a first-in-human study, researchers treated relapsed patients with gilteritinib, an FLT3 inhibitor, and found it was a well-tolerated drug that led to frequent and more-sustained-than-expected clinical responses, almost exclusively in patients with this mutation.



Advances in AI for drug discovery to be presented at the AI Pharma Innovation Summit 2017 in Boston

Wed, 21 Jun 2017 00:00:00 EDT

(InSilico Medicine, Inc.) Insilico Medicine will present new research and moderate the workshop titled 'A Fundamental Guide to the Application of AI in Drug Discovery to Uncover the Next Wave of Successful Future Candidates.'