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EurekAlert! - Cancer Research News



The premier online source for science news since 1996. A service of the American Association for the Advancement of Science.



Last Build Date: Sat, 21 Jan 2017 19:54:02 EST

Copyright: Copyright 2017 American Association for the Advancement of Science (AAAS); All rights reserved.
 



IT network upgrades support LSUHealthNO research enterprise

Thu, 19 Jan 2017 00:00:00 EST

(Louisiana State University Health Sciences Center) The Department of Information Technology at LSU Health New Orleans successfully competed for its first National Science Foundation grant. The $499,640 grant will support a complete cyberinfrastructure overhaul in two key research buildings to create a science demilitarized zone (DMZ) and a high-speed science network for LSU Health New Orleans researchers.



Breast cancer prognosis of African-American patients may improve with chemotherapy before surgery

Thu, 19 Jan 2017 00:00:00 EST

(Georgia State University) Administering chemotherapy to African-American breast cancer patients prior to surgery could improve their prognosis and survival rates from the disease, according to a new study.



Pancreatic tumors rely on signals from surrounding cells

Thu, 19 Jan 2017 00:00:00 EST

(Salk Institute) Salk scientists find that targeting the interaction between a pancreatic tumor and its microenvironment could weaken cancer



Digital assay of circulating tumor cells may improve diagnosis, monitoring of liver cancer

Thu, 19 Jan 2017 00:00:00 EST

(Massachusetts General Hospital) Use of an advanced form of the commonly used polymerase chain reaction method to analyze circulating tumor cells may greatly increase the ability to diagnose early-stage cancer, increasing the likelihood of successful treatment.



Mayo researchers identify mechanism of oncogene action in lung cancer

Thu, 19 Jan 2017 00:00:00 EST

(Mayo Clinic) Researchers at Mayo Clinic have identified a genetic promoter of cancer that drives a major form of lung cancer. In a new paper published this week in Cancer Cell, Mayo Clinic researchers provide genetic evidence that Ect2 drives lung adenocarcinoma tumor formation.



As cells age, the fat content within them shifts

Thu, 19 Jan 2017 00:00:00 EST

(University at Buffalo) As cells age and stop dividing, their fat content changes, along with the way they produce and break down fat and other molecules classified as lipids. By providing broad insights into the connection between lipids and cellular aging, the findings open the door for additional research that could support the development of lipid-based approaches to preventing cell death or hastening it in cancerous tumors.



Press registration now open for 2017 Experimental Biology meeting

Thu, 19 Jan 2017 00:00:00 EST

(Experimental Biology 2017) Press registration is open for the 2017 Experimental Biology meeting (EB 2017) to be held in Chicago April 22-26. With more than 14,000 attendees and thousands of scientific sessions, EB 2017 is a research bonanza you won't want to miss.



CRISPR meets single-cell sequencing in new screening method

Thu, 19 Jan 2017 00:00:00 EST

(CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences) A new cell screening method combines two revolutionary tools of biomedical research: Scientists at CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences have integrated CRISPR genome editing with single-cell RNA sequencing. Their study establishes a method for studying gene regulation in unprecedented scale and detail.



Precision medicine advances pediatric brain tumor diagnosis and treatment

Thu, 19 Jan 2017 00:00:00 EST

(Dana-Farber Cancer Institute) In the largest clinical study to date of genetic abnormalities in pediatric brain tumors, researchers performed clinical testing on more than 200 tumor samples and found that a majority had genetic irregularities that could influence how the disease was diagnosed and/or treated with approved drugs or agents being evaluated in clinical trials.



HPV prevalence rates among US men, vaccination coverage

Thu, 19 Jan 2017 00:00:00 EST

(The JAMA Network Journals) Human papillomavirus (HPV) infection is the most common sexually transmitted infection in the United States, as well as a cause of various cancers, and a new study published online by JAMA Oncology estimates the overall prevalence of genital HPV infection in men ages 18 to 59.



Jumbled chromosomes may dampen the immune response to tumors

Thu, 19 Jan 2017 00:00:00 EST

(American Association for the Advancement of Science) How well a tumor responds to immunotherapy may depend in part on whether its chromosomes are intact or in a state of disarray, a new study reports. The finding could help doctors better pinpoint which cancer patients would benefit from immunotherapy.



Roots of related genetic diseases found in cell powerhouses

Thu, 19 Jan 2017 00:00:00 EST

(NYU Langone Medical Center / New York University School of Medicine) Scientists at NYU Langone Medical Center have discovered the mechanisms behind a genetic change known to cause a set of related diseases.



Bodywide immune response important for fighting cancer, Stanford researchers say

Thu, 19 Jan 2017 00:00:00 EST

(Stanford University Medical Center) Effective anti-tumor activity requires a systemic, rather than only a local, immune response at the tumor site. The findings from a Stanford study may help clinicians pinpoint why only some cancer patients respond to immunotherapies.



Actress Kathy Bates to be honored at Research!America's Advocacy Awards Dinner

Wed, 18 Jan 2017 00:00:00 EST

(Research!America) Kathy Bates, award-winning actress and Lymphatic Education & Research Network (LE&RN) spokesperson, will receive Research!America's Isadore Rosenfeld Award for Impact on Public Opinion for raising the visibility of lymphedema and lymphatic diseases and advocating tirelessly on behalf of the patient community. The Rosenfeld Award is presented to individuals who have worked to effectively deliver medical or other health-related research advocacy messages to the public.



Special issue highlights research at UM Schools of Medicine and Dentistry

Wed, 18 Jan 2017 00:00:00 EST

(University of Maryland School of Medicine) New research by scientists at the University of Maryland School of Medicine and the University of Maryland School of Dentistry, is highlighted in a special issue of Pathogens and Disease.



Small intestine GIST associated with better prognosis in younger patients

Wed, 18 Jan 2017 00:00:00 EST

(University of California - San Diego) Gastrointestinal stromal tumors (GIST) are tumors that arise is the wall of the digestive tract, and most often occur in the stomach or small intestine. Though more common in later in life, GISTs can occur in adolescents and young adults (AYA) under 40 years old as well. Researchers at the University of California San Diego School of Medicine report findings from the first population-based analysis of AYA patients with GIST.



RIT engineer researches the impact of shear stress on cell circulation

Wed, 18 Jan 2017 00:00:00 EST

(Rochester Institute of Technology) Jiandi Wan, an assistant professor of microsystems engineering in Rochester Institute of Technology's Kate Gleason College of Engineering, recently received a $476,505 award from the Gordon and Betty Moore Foundation for his work using fluid dynamics and mechano-biology strategies to better understand blood flow and how cells moving through blood vessels are affected by shear stress



Advanced stage NSCLC patients receiving treatment have better OS than untreated patients

Wed, 18 Jan 2017 00:00:00 EST

(International Association for the Study of Lung Cancer) Non-small cell lung cancer (NSCLC) patients with advanced disease receiving standard of care treatment have a higher overall survival (OS) than similar patients not receiving treatment.



Researcher examines effect of exercise on breast cancer survivors

Wed, 18 Jan 2017 00:00:00 EST

(Syracuse University) Gwendolyn Thomas, assistant professor of exercise science, is the co-author of a groundbreaking article in the Obesity Journal (The Obesity Society, 2017) about the effects of exercise and physical activity on postmenopausal breast cancer survivors taking AIs -- hormone-therapy drugs that stop the production of estrogen. She contends that a combination of resistance and aerobic exercise helps mitigate the side effects of AIs and improves health outcomes in breast cancer survivors, particularly their body composition.



Affordable Care Act made cancer screening more accessible for millions, study finds

Wed, 18 Jan 2017 00:00:00 EST

(University of Virginia Health System) From 2011 to 2013, the ACA resulted in an 8 percent increase in the diagnoses of early-stage colorectal cancer among US seniors aged 65 and older.



SWOG launches national immunotherapy clinical trial for rare cancers

Wed, 18 Jan 2017 00:00:00 EST

(SWOG) People with rare cancers now have the option of joining a national clinical trial testing leading-edge immunotherapies for a wide variety of tumor types. It's the first federally funded immunotherapy trial devoted to rare cancers. Despite their name, rare cancers make up more than 20 percent of cancers diagnosed worldwide.



A new prognostic classification may help clinical decision-making in glioblastoma

Wed, 18 Jan 2017 00:00:00 EST

(Ohio State University Wexner Medical Center) New research shows that taking molecular variables into account will improve the prognostic classification of the lethal brain cancer called glioblastoma (GBM). Published in the journal JAMA Oncology, the study found that adding significant molecular biomarkers to the existing GBM classification system improves the prognostic classification of GBM patients who have been treated with radiation and the drug temozolomide.



Biosimilars create opportunities for sustainable cancer care

Wed, 18 Jan 2017 00:00:00 EST

(European Society for Medical Oncology) Biosimilars create opportunities for sustainable cancer care, says the European Society for Medical Oncology in a position paper published in ESMO Open. The document outlines approval standards for biosimilars, how to safely introduce them into the clinic, and the potential benefits for patients and healthcare systems.



UK's Pancreatic Cancer Research Fund announces latest grant awards

Wed, 18 Jan 2017 00:00:00 EST

(Pancreatic Cancer Research Fund) Five research projects with potential to make a real difference to tackling pancreatic cancer have been awarded grants by the UK charity Pancreatic Cancer Research Fund, worth over £800,000 in total.



Mount Sinai researchers involved in successful phase 3 trial of drug for liver cancer

Wed, 18 Jan 2017 00:00:00 EST

(The Mount Sinai Hospital / Mount Sinai School of Medicine) An international phase 3 trial has found that the drug regorafenib improved survival in patients with advanced hepatocellular carcinoma, a form of liver cancer, giving people who previously had no other options a better chance at survival. Results from the study, which included researchers at The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai, were recently published in The Lancet. The trial, funded by Bayer, included 152 sites in 21 countries.