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Preview: EurekAlert! - Cancer

EurekAlert! - Cancer Research News



The premier online source for science news since 1996. A service of the American Association for the Advancement of Science.



Last Build Date: Fri, 28 Apr 2017 21:54:01 EDT

Copyright: Copyright 2017 American Association for the Advancement of Science (AAAS); All rights reserved.
 



MDI Biological Laboratory scientist receives grant to study peripheral neuropathy

Fri, 28 Apr 2017 00:00:00 EDT

(Mount Desert Island Biological Laboratory) The MDI Biological Laboratory has announced that Sandra Rieger, Ph.D., has been awarded a highly competitive grant from the National Cancer Institute, an institute of the National Institutes of Health (NIH), to study the molecular mechanisms underlying chemotherapy-induced peripheral neuropathy, a side effect of cancer chemotherapy causing symptoms such as pain, tingling, temperature sensitivity and numbness in the extremities.



China builds world's largest kinase-based whole-cell screening library

Fri, 28 Apr 2017 00:00:00 EDT

(Chinese Academy of Sciences Headquarters) After five years of hard work, China has completed the world's largest kinase-based whole-cell screening library for high-throughput drug assay. The cell library is located in Hefei, capital of Anhui Province, and includes over 150 cell lines. The library covers more than 70 different kinases and mutations that are involved in human tumorigenesis and have been targeted through clinical treatment.



Single gene encourages growth of intestinal stem cells, supporting 'niche' cells -- and cancer

Fri, 28 Apr 2017 00:00:00 EDT

(Johns Hopkins Medicine) A gene previously identified as critical for tumor growth in many human cancers also maintains intestinal stem cells and encourages the growth of cells that support them, according to results of a study led by Johns Hopkins researchers. The finding, reported in the April 28 issue of Nature Communications, adds to evidence for the intimate link between stem cells and cancer, and advances prospects for regenerative medicine and cancer treatments.



Unraveling the mystery of DNA attacks in cells' powerhouse could pave way for new cancer treatments

Fri, 28 Apr 2017 00:00:00 EDT

(University of Sheffield) New research has unraveled the mystery of how mitochondria -- the energy generators within cells -- can withstand attacks on their DNA from rogue molecules.



When the smoke clears... tobacco control in post-conflict settings

Fri, 28 Apr 2017 00:00:00 EDT

(ecancermedicalscience) In new research published today by King's College London - Institute of Cancer Policy and the Conflict & Health Research Group in the journal ecancermedicalscience, the difficulties of prioritizing preventable disease and long term health issues in post conflict zones are explored.



Allina Health shares LifeCourse model at the Institute for Clinical Systems Improvement

Thu, 27 Apr 2017 00:00:00 EDT

(Allina Health ) In an Allina Health study, the LifeCourse care model improved patient experience and reduced costs for people with serious illnesses. Researchers say the model is ready for replication.



Treatment improved overall survival in elderly patients with early-stage esophageal cancer

Thu, 27 Apr 2017 00:00:00 EDT

(International Association for the Study of Lung Cancer) Elderly patients with early-stage esophageal cancer that received treatment had an increased 5-year overall survival when compared to patients who received observation with no treatment.



VUMC to study potential approach to reverse precancerous stomach lesions

Thu, 27 Apr 2017 00:00:00 EDT

(Vanderbilt University Medical Center) Vanderbilt University Medical Center (VUMC) cancer researcher James Goldenring, M.D., Ph.D., has received a two-year, $200,000 grant from the DeGregorio Family Foundation in Pleasantville, New York, to begin clinical trials of a potential approach for reversing precancerous stomach lesions.



Mouse teeth providing new insights into tissue regeneration

Thu, 27 Apr 2017 00:00:00 EDT

(University of California - San Francisco) Researchers hope to one day use stem cells to heal burns, patch damaged heart tissue, even grow kidneys and other transplantable organs from scratch.



Sidney Kimmel Foundation concludes cancer research grant program with final recipients

Thu, 27 Apr 2017 00:00:00 EDT

(Sidney Kimmel Foundation ) After two decades and just under 300 award winners, The Sidney Kimmel Foundation has selected the final 15 research scientists and medical doctors from across the US to receive two-year grants totaling $200,000 each, as part of the prestigious Kimmel Scholars Program.



Pregnancy does not increase expectant mothers' melanoma risk

Thu, 27 Apr 2017 00:00:00 EDT

(American College of Surgeons) Expectant mothers need not be concerned that they are more prone to develop melanoma, or will have a worse prognosis if they do get this serious skin cancer, than women who are not pregnant, according to study results published online as an 'article in press' on the Journal of the American College of Surgeons website ahead of print publication.



Molecule identified that helps give resident T cells in the skin their anti-cancer punch

Thu, 27 Apr 2017 00:00:00 EDT

(Medical University of South Carolina) The molecule CD103 is key to the long-term residence of T cells in the skin and to their anti-tumor function, report a collaborative team of researchers at the Medical University of South Carolina and Dartmouth In the April 14, 2017 Science Immunology. This finding supplements the ground-breaking discovery by the Dartmouth researchers that T cells residing in the skin are responsible for a potent anti-tumor response against melanoma.



Computational research details the activation mechanism of p38α

Thu, 27 Apr 2017 00:00:00 EDT

(Institute for Research in Biomedicine (IRB Barcelona)) p38α is a protein involved in chronic inflammatory diseases and cancer, among other pathological conditions.Published in the journal eLife, the study provides a deeper understanding of the structure of this protein, thereby paving the way for the development of more effective inhibitors.These findings are the result of combining fundamental biological data using computational techniques.



NETRF makes $4 Million in grants to advance research of a poorly understood cancer

Thu, 27 Apr 2017 00:00:00 EDT

(Neuroendocrine Tumor Research Foundation) The Neuroendocrine Tumor Research Foundation (NETRF) announced its largest research commitment ever to study neuroendocrine tumors (NETs), a widely misunderstood, commonly misdiagnosed cancer type, without adequately identified genomic drivers



'Outstanding' results announced from new blood cancer study

Thu, 27 Apr 2017 00:00:00 EDT

(University of Leicester) Research led by University of Leicester and University Hospitals of Leicester NHS Trust reveals 'transformative outcomes' for patients with chronic lymphocytic leukemia.



E-cigarettes do not promote cancer growth in lab tests

Thu, 27 Apr 2017 00:00:00 EDT

(Wiley) A new study found no evidence that a commercially available e-cigarette vapor promotes the development of cancer in laboratory cells. In contrast, smoke from a reference cigarette was positive for cancer-promoting activity at very low concentrations.



Latest advances in artificial intelligence for drug discovery to be presented at the NVIDIA GTC

Thu, 27 Apr 2017 00:00:00 EDT

(InSilico Medicine, Inc.) Insilico Medicine, Inc, is a big data analytics company specializing in applying the latest advances in deep learning to drug discovery, biomarker development and aging research. In the NVIDIA Graphics Technology Conference (GTC), the scientists from Insilico Medicine will present its latest progress on the applications of Generative Adversarial Networks to Drug Discovery in Oncology and Infectious Diseases.



Follow-up colonoscopies associated with a significantly lower incidence of bowel cancer

Thu, 27 Apr 2017 00:00:00 EDT

(Imperial College London) Patients at risk of developing bowel cancer can significantly benefit from a follow-up colonoscopy, finds research published today in Lancet Oncology.



England's Cancer Drugs Fund 'failed to deliver meaningful value to patients and society'

Thu, 27 Apr 2017 00:00:00 EDT

(European Society for Medical Oncology) Analysis of the drugs that were approved for use by the NHS Cancer Drugs Fund (CDF) in England has shown that the fund was not good value for patients and society and may have resulted in patients suffering unnecessarily from toxic side effects of the drugs. The review by Professor Richard Sullivan and Dr. Ajay Aggarwal is published in Annals of Oncology with an accompanying editorial by Dr. Kapil Dhingra.



Cleveland Clinic discovers opportunities to overcome cancer treatment resistance

Thu, 27 Apr 2017 00:00:00 EDT

(Cleveland Clinic) A collaborative Cleveland Clinic, University of Oxford and Moffitt Cancer Center team of researchers has proven the theory that, while resistance to targeted treatment in cancer is truly a moving target, there are opportunities to overcome the resistance that develops.



Chemoresistance in breast cancer is related to varying tumor cell populations

Thu, 27 Apr 2017 00:00:00 EDT

(IDIBELL-Bellvitge Biomedical Research Institute) IDIBELL scientists have recreated and characterized the process of acquisition of resistance to chemotherapy in orthotopic animal models of breast cancer, unveiling the possibility of reversing this resistance after a period of rest from the treatment.



New fiber optic probe brings endoscopic diagnosis of cancer closer to the clinic

Thu, 27 Apr 2017 00:00:00 EDT

(The Optical Society) In an important step toward endoscopic diagnosis of cancer, researchers have developed a handheld fiber optic probe that can be used to perform multiple nonlinear imaging techniques without the need for tissue staining.



HHMI awards medical research fellowships to 79 students

Wed, 26 Apr 2017 00:00:00 EDT

(Howard Hughes Medical Institute) The Howard Hughes Medical Institute's (HHMI) Medical Research Fellows Program has selected 79 talented medical and veterinary students to conduct in-depth, mentored biomedical research. Each fellow will spend a year pursuing basic, translational, or applied biomedical research at one of 32 academic or nonprofit research institutions across the United States.



Italian-style coffee reduces the risk of prostate cancer

Wed, 26 Apr 2017 00:00:00 EDT

(Istituto Neurologico Mediterraneo Neuromed I.R.C.C.S.) Add another typical component of the Italian way of life to the list of foods characterizing one of the most healthy populations in the world. This time it's coffee, prepared the Italian way. A research by the Department of Epidemiology and Prevention - I.R.C.C.S. Neuromed, Italy, in collaboration with the Italian National Institute of Health and the I.R.C.C.S. Istituto Dermopatico dell'Immacolata, shows that three or more cups a day can lower prostate cancer risk.



Study signals need to screen genes for stem cell transplants

Wed, 26 Apr 2017 00:00:00 EDT

(Harvard University) New research shows that as stem cell lines grow in a lab dish, they often acquire mutations in the TP53 (p53) gene, an important tumor suppressor responsible for controlling cell growth. Findings suggest that genetic sequencing technologies should be used to screen for mutated cells in stem cell cultures, so that cultures with mutated cells can be excluded from experiments and therapies.