Last Build Date: Thu, 08 Dec 2016 23:00:01 ESTCopyright: Copyright 2016 American Association for the Advancement of Science (AAAS); All rights reserved.
Thu, 08 Dec 2016 00:00:00 ESTScientists have focused on certain p53 mutations that generate mutant proteins that promote cancer growth and metastasis. The variants studied are truncated -- they lack half of the domains, or units, of the full-length p53 protein, which enable full-length p53 to enter the cell nucleus and bind DNA, essential in its normal tumor-suppressor function. The truncated mutants act by perturbing mitochondrial function, the team proposes.
Thu, 08 Dec 2016 00:00:00 ESTA recently discovered galaxy is undergoing an extraordinary boom of stellar construction, revealed by a group of astronomers led by University of Florida graduate student Jingzhe Ma using NASA's Chandra X-Ray Observatory.
Thu, 08 Dec 2016 00:00:00 ESTTurning meadow restoration into cleaner air is the goal of researchers at the University of Nevada, Reno. Their Soil Science Laboratory recently partnered with the Earthwatch Institute to better understand how restoration and plant communities relate to the soil carbon in Sierra Nevada mountain meadows. The team aims to develop a model that can predict how much carbon is sequestered in a meadow. The data may be used by the State of California to sell carbon credits through their Cap and Trade program.
Thu, 08 Dec 2016 00:00:00 ESTScientists from WCS (Wildlife Conservation Society), The Nature Conservancy, and several partners in Brazil and Peru have produced a geographic information system (GIS) 'roadmap' to help guide conservation efforts at large scale in the Amazon River basin, a region roughly the size of the United States.
Thu, 08 Dec 2016 00:00:00 ESTArticle describes latest research on magnetic reconnection.
Thu, 08 Dec 2016 00:00:00 ESTResearchers at UMass Medical School and the University of Toronto have discovered the first known 'off-switches' for CRISPR/Cas9 genome editing, providing much greater control over the edits, according to a new study published in Cell. Erik Sontheimer, PhD, led the research at UMMS.
Thu, 08 Dec 2016 00:00:00 ESTA researcher from UH Seidman Cancer Center will discuss his upcoming immunotherapy clinical trial for triple-negative breast cancer at 2016 San Antonio Breast Cancer Symposium. Joseph Baar, MD, PhD, Director of Breast Cancer Research at UH Seidman Cancer Center, will share details about a phase II clinical trial testing the effectiveness of combining carboplatin and nab-paclitaxel with an immunotherapeutic agent called pembrolizumab in patients with metastatic triple-negative breast cancer.
Thu, 08 Dec 2016 00:00:00 ESTOHSU Knight Cancer Institute oncologist publishes New England Journal of Medicine 'Perspective' on her experience treating a patient in rural Oregon with breast cancer, mental illness.
Thu, 08 Dec 2016 00:00:00 ESTAs many as a quarter of all older adults discharged from an acute hospitalization will return within thirty days. Readmissions like these result in increased healthcare costs, functional decline and greater need for skilled nursing when transitioning back to community settings. Older black patients bear a disproportionate risk of readmissions according to the Centers for Disease Control and Prevention and no single approach has been repeatedly effective in reducing readmissions for older black patients.
Thu, 08 Dec 2016 00:00:00 ESTMIT Prof. Tavneet Suri is co-author of a new paper showing that mobile-money services have had notable long-term effects on poverty reduction in Kenya -- especially among female-headed households -- and have inspired a surprising occupation shift among women.Published in today's issue of Science, the study estimates that, since 2008, access to mobile-money services increased daily per capita consumption levels of 194,000 -- or 2 percent -- of Kenyan households, lifting them out of extreme poverty.
Thu, 08 Dec 2016 00:00:00 ESTNational Transportation Safety Board (NTSB) officials often rely on digital clues left behind in flash memories of any and all electronic devices at a crash site. With the physical forces and high-temperature fires associated with many crashes, memory units are often damaged and sometimes unreadable.Researchers at Binghamton University have figured out how much damage memory units can sustain before becoming unreadable and new repair techniques to retrieve clues off of damaged units, which might help prevent future tragedies.
Thu, 08 Dec 2016 00:00:00 ESTThe violence that women in disadvantaged neighborhoods experience and witness can result in post-traumatic stress disorder (PTSD) symptoms and full diagnoses, according to a new Northwestern Medicine study that examined a disadvantaged Chicago neighborhood.
Thu, 08 Dec 2016 00:00:00 ESTA new study found that traditional bullets for muzzleloading rifles and black powder rifle cartridges fragment less upon impact and may leave far fewer lead fragments in game than a modern high-velocity rifle bullet.
Thu, 08 Dec 2016 00:00:00 ESTA meta-analysis of genome-wide association studies (GWAS) has identified six loci or regions of the human genome that are significantly linked to personality traits, report researchers at University of California San Diego School of Medicine in this week's advance online publication of Nature Genetics. The findings also show correlations with psychiatric disorders.
Thu, 08 Dec 2016 00:00:00 ESTVeterans Affairs researchers and colleagues are looking to satellites and airport visibility readings to learn about hazardous air conditions facing deployed troops.
Thu, 08 Dec 2016 00:00:00 ESTTwo new studies out of Case Western Reserve University School of Medicine describe how the inflammatory response to psoriasis can alter levels of several immune system molecules, ultimately increasing a person's risk of thrombosis, which can include fatal blood clots.
Thu, 08 Dec 2016 00:00:00 ESTResearchers discover a protein that inhibits biofilms of a bacterium responsible for many cystic fibrosis infections.
Thu, 08 Dec 2016 00:00:00 ESTWhat we see in the periphery, just outside the direct focus of the eye, may sometimes be a visual illusion, according to new findings published in Psychological Science. The findings suggest that even though our peripheral vision is less accurate and detailed than what we see in the center of the visual field, we may not notice a qualitative difference because our visual processing system actually fills in some of what we 'see' in the periphery.
Thu, 08 Dec 2016 00:00:00 ESTSelf-harm was the leading cause of pregnancy-associated deaths in Colorado from 2004 to 2014, ahead of car crashes, medical conditions and homicide, according to researchers at the University of Colorado Anschutz Medical Campus.
Thu, 08 Dec 2016 00:00:00 ESTResearchers report at the San Antonio Breast Cancer Symposium that they have identified biomarkers they believe can be used as part of a larger model to predict how patients with HER2-positive operative breast cancer will respond to the targeted treatment trastuzumab, commercially known as Herceptin, and chemotherapy.
Thu, 08 Dec 2016 00:00:00 ESTOne of the most sophisticated networks of acoustic detectors ever developed for wildlife science has documented a devastating 34 percent per year decline of Mexico's critically endangered vaquita porpoise, according to a new study published today in the journal Conservation Biology. A companion paper published today in Conservation Letters uses both acoustic and visual surveys to estimate that only about 60 vaquitas remained, as of last year.
Thu, 08 Dec 2016 00:00:00 ESTDuke University researchers have identified a common mechanism underlying separate forms of dystonia, a family of brain disorders that cause involuntary, debilitating and often painful movements, including twists and turns of different parts of the body. The research has led to the development of a new cell-based test that is being deployed on a large scale to identify new drug candidates to treat dystonia.
Thu, 08 Dec 2016 00:00:00 ESTPatients with depression can be categorized into four unique subtypes defined by distinct patterns of abnormal connectivity in the brain, according to new research from Weill Cornell Medicine.
Thu, 08 Dec 2016 00:00:00 ESTBattery researchers have used a special electron microscope with atomic-level resolution to show that certain large ions can hold open tunnels in a promising electrode material, so that charge-carrying ions like lithium can enter and exit the electrode easily and quickly -- boosting capacity.
Thu, 08 Dec 2016 00:00:00 ESTResearchers create a global map of soil pH and illuminate how it changes between wet and dry climates.
Thu, 08 Dec 2016 00:00:00 ESTAfter decades of eluding researchers because of chemical instability, key metal-oxide clusters have been isolated in water, a significant advance for growing the clusters with the impeccable control over atoms that's required to manufacture small features in electronic circuits.
Thu, 08 Dec 2016 00:00:00 EST15-year PLCO results published this month in Cancer: 'Most men diagnosed with prostate cancer will not die from their disease... now we need to focus on discovering the men that will,' says E. David Crawford, M.D., investigator at the University of Colorado Cancer Center.
Thu, 08 Dec 2016 00:00:00 ESTResearchers have begun to map the brain circuitry responsible for cultural transmission and species specificity in birdsong.
Thu, 08 Dec 2016 00:00:00 ESTNew research from Indiana University's Kelley School of Business highlights common mistakes that people will make this holiday season, including thinking more about the moment they expect when giving a present than the many moments after when their recipients keep and use the gift.
Thu, 08 Dec 2016 00:00:00 ESTResearchers at the Institute of Molecular Biology (IMB) and Johannes Gutenberg University Mainz (JGU) have shown that a new way of regulating genes is vital for the activity of the nervous system. They found that this form of regulation, a chemical modification on RNA called m6A, is also important in influencing whether flies become male or female. This study clearly shows that RNA modifications play an important role.
Thu, 08 Dec 2016 00:00:00 ESTNothing ruins a potentially fun event like putting it on your calendar. In a series of studies, researchers found that scheduling a leisure activity like seeing a movie or taking a coffee break led people to anticipate less enjoyment and actually enjoy the event less than if the same activities were unplanned.
Thu, 08 Dec 2016 00:00:00 ESTAs NASA's Aqua satellite passed over the Bay of Bengal, Tropical Cyclone 05B was renamed Vardah and continued moving away from the Andaman and Nicobar Islands.
Thu, 08 Dec 2016 00:00:00 ESTThe 2016 Ocean Health Index shows no major declines -- and few real improvements.
Thu, 08 Dec 2016 00:00:00 ESTA new Rice University study finds that migration for the first humans in America was easier moving east-west as opposed to north-south, largely because the knowledge needed to live in the same climate zones was easily transferable. Researchers said the findings could also shed light on the behavior of metastatic cancers.
Thu, 08 Dec 2016 00:00:00 ESTResearchers from the Michael & Susan Dell Center for Healthy Living at The University of Texas Health Science Center at Houston (UTHealth) School of Public Health were the senior scientific editors for the first-ever US Surgeon General's Report on E-Cigarette Use Among Youth and Young Adults, released today.
Thu, 08 Dec 2016 00:00:00 ESTResearchers have discovered a way to program cells to inhibit CRISPR-Cas9 activity. 'Anti-CRISPR' proteins had previously been isolated from viruses that infect bacteria, but now University of Toronto and University of Massachusetts Medical School scientists report three families of proteins that turn off CRISPR systems specifically used for gene editing. The work, which appears December 15 in Cell, offers a new strategy to prevent CRISPR-Cas9 technology from making unwanted changes.
Thu, 08 Dec 2016 00:00:00 ESTA severely brain injured woman, who recovered the ability to communicate using her left eye, restored connections and function of the areas of her brain responsible for producing expressive language and responding to human speech, according to new research from Weill Cornell Medicine scientists.
Thu, 08 Dec 2016 00:00:00 ESTWhile many voters reported long lines at polling locations around the country during the 2012 presidential election, this year the overall amount of time people had to wait to vote improved significantly, according to a new survey examining voter experience during the 2016 presidential election. MIT Professor Charles Stewart III presented the preliminary findings of the Survey on the Performance of American Elections, during a conference hosted by the Pew Charitable Trusts.
Thu, 08 Dec 2016 00:00:00 ESTAntibody-based immunotherapy is a new promising method to treat cancer. Unfortunately, today's treatments can result in adverse side effects. New findings from Uppsala University show an alternative way to administer the therapy, which has the same effect on the tumor but less impact other parts of the body.
Thu, 08 Dec 2016 00:00:00 ESTAn international team of scientists has succeeded in making further improvements to the lifetime of superconducting quantum circuits. An important prerequisite for the realization of high-performance quantum computers is that the stored data should remain intact for as long as possible. The researchers, including Jülich physicist Dr. Gianluigi Catelani, have developed and tested a technique that removes unpaired electrons from the circuits. These are known to shorten the qubit lifetime.
Thu, 08 Dec 2016 00:00:00 ESTWhen flawed clinical research is reported in the media with hype and sensationalism, it has the potential to have a devastating effect on patients, physicians, the scientific community and eventually society as a whole. In a review article in the journal EMBO Reports, the authors question how controversial and weak studies are publicized by the media and often coupled with a narrative that is either false or with little scientific basis.
Thu, 08 Dec 2016 00:00:00 ESTJust because temperatures are cooling down as winter approaches, it's no time to let your guard down when it comes to mosquitoes that can carry the Zika virus. LSU Health New Orleans' Dr. James Diaz details characteristics of the mosquitoes capable of transmitting the Zika virus in the United States, their habitats and biting behaviors, as well as control measures, in a paper published in the December 2016, issue of Wilderness & Environmental Medicine.
Thu, 08 Dec 2016 00:00:00 ESTTiny predators in the soil can literally sniff out their prey: soil bacteria, which communicate with each other using scent. A team of researchers from the Netherlands Institute of Ecology (NIOO-KNAW) has discovered that these predators -- called protists - 'eavesdrop' on the bacteria's communication. It's a discovery that opens up perspectives for agriculture. The results are available online this month in The ISME Journal, from the publishers of Nature.
Thu, 08 Dec 2016 00:00:00 ESTPushing nanoscale battery developments in the right direction can help create a sustainable transport sector.
Thu, 08 Dec 2016 00:00:00 ESTIn children on the spectrum, anxiety is often masked by the symptoms of autism. But a new variant to a standard anxiety screening method has now proven effective in separating the two and it is leading to important diagnoses.
Thu, 08 Dec 2016 00:00:00 ESTPreventing dementia is a major public health priority worldwide, and intense work is being conducted to formulate effective preventive strategies. Healthy lifestyle changes may help prevent cognitive decline and dementia, but the challenge is to detect early on those who are most at risk and to choose the most relevant preventive measures.
Thu, 08 Dec 2016 00:00:00 ESTA research team led by Jefferson Lab's Robert Edwards has been using computation to inform GlueX experiments at Jefferson Lab as well as corroborate experimental findings.
Thu, 08 Dec 2016 00:00:00 ESTA well-chosen metaphor does wonders to explain concepts, to persuade and to ensure buy-in into any given matter. So says Paul Thibodeau of Oberlin College in the US, lead author of an article in Springer's journal Psychonomic Bulletin & Review on the use of metaphors as a form of explanation.
Thu, 08 Dec 2016 00:00:00 ESTClimate engineering refers to the systematic, large-scale modification of the environment using various climate intervention techniques.
Thu, 08 Dec 2016 00:00:00 ESTNew research finds that a woman's lifetime history of drug use can help predict whether the woman will suffer from problems with stress and anxiety after childbirth. The finding could help health-care providers screen pregnant women for mental health problems and provide relevant treatment.
Thu, 08 Dec 2016 00:00:00 ESTSome patients with Crohn's disease, a chronic inflammatory disease that affects the lining of the digestive tract, require surgery to remove part or all of the large intestine; however, surgery does not cure the condition and many patients relapse after surgery.
Thu, 08 Dec 2016 00:00:00 ESTABIVAX presented new preclinical data on ABX464, its first-in-class drug candidate for a functional cure of patients with HIV/AIDS, during this week's HIV DART (Frontiers in Drug Development for Antiretroviral Therapy) conference in Los Cabos, Mexico. The data also show a strong anti-inflammatory effect suggesting a broadening therapeutic potential. A clinical study in IBD will start in 2017.
Thu, 08 Dec 2016 00:00:00 ESTScientists at the Hebrew University of Jerusalem have found that higher Body Mass Index (BMI), if it begins in adolescence, can affect cognitive function in midlife. However, the effect appears to be restricted to adults who had a lower socioeconomic position as children.
Thu, 08 Dec 2016 00:00:00 ESTIn a study conducted by the Helsinki Institute for Information Technology (HIIT) and the Centre of Excellence in Computational Inference (COIN), laboratory test subjects read the introductions of Wikipedia articles of their own choice. During the reading session, the test subjects' EEG was recorded, and the readings were then used to model which key words the subjects found interesting.
Thu, 08 Dec 2016 00:00:00 ESTLinking GPs' pay to their performance has no discernible effect on their job satisfaction, a University of Manchester study of almost 2,000 UK doctors over a four-year period has found.
Thu, 08 Dec 2016 00:00:00 ESTResearchers from Aarhus University, Denmark, have come closer to answering the question of how the brain defends itself against viral infections. In the long term, the discovery may turn out to be very important for the treatment of diseases of the brain in which the immune system is involved such as multiple sclerosis, Alzheimer's disease and potentially also psychiatric disorders.
Thu, 08 Dec 2016 00:00:00 ESTPhysicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.
Thu, 08 Dec 2016 00:00:00 ESTSearch engines and content providers could have a role to play in helping young people find the most reliable mental health resources online, research at the University of Strathclyde has found.
Thu, 08 Dec 2016 00:00:00 ESTDeficiency in a certain protein in the gastrointestinal tract has been shown to lead to both inflammation and abdominal fat accumulation in mice. The discovery provides yet another piece of the puzzle of how humans are affected -- or not -- by the large quantities of intestinal bacteria we carry with us.
Thu, 08 Dec 2016 00:00:00 ESTResearchers at Lund and Malmö universities in Sweden have measured a biomarker in cell-free blood plasma which can be linked to an overactive stress system in suicidal individuals. This biomarker can hopefully be used in future psychiatric studies.
Thu, 08 Dec 2016 00:00:00 ESTA research team affiliated with Ulsan National Institute of Science and Technology has developed liquid-like TE materials that can be painted on almost any surface. This new technology can convert exhaust heat into electricity for vehicles and other applications.
Thu, 08 Dec 2016 00:00:00 ESTThe honeybee can form complex memories through processes much like those happening in human brains. This study shows that DNA methylation is one molecular mechanism that regulates memory specificity and re-learning, and as such, could control how experiences are integrated over a lifetime.
Thu, 08 Dec 2016 00:00:00 ESTOsaka University-led research revealed contrasting roles for the SNAP23 protein in pancreatic secretion of digestive enzymes and hormones such as insulin. Inhibiting SNAP23 with a potential new diabetes drug enabled an alternative related protein of higher efficacy to compensate for its function and increase insulin secretion in mice. The novel therapy also shows promise as a treatment for pancreatitis.
Thu, 08 Dec 2016 00:00:00 ESTHeavy alcohol use during adolescence alters the development of brain, according to a recent study from the University of Eastern Finland and Kuopio University Hospital. Cortical thinning was observable in young people who had been heavy drinkers throughout their adolescence.
Thu, 08 Dec 2016 00:00:00 ESTWhen escaping from attacking predators, different water strider species adjust their jump performance to their mass and morphology in order to jump off the water as fast and soon as possible without breaking of the water surface.
Thu, 08 Dec 2016 00:00:00 ESTScientists at the Tokyo Institute of Technology utilized micro-flow amide bond formation to achieve total synthesis of the structurally complex, biologically active natural product, feglymycin. The technique they developed allows for efficient preparation of requisite oligopeptides containing highly racemizable amino acids and could directly impact how these agents will be synthesized in the future.
Thu, 08 Dec 2016 00:00:00 ESTBe it sand, snow or a bowl of spices, rendering massive aggregations of granular materials is a challenge for animators. A new method developed by researchers from Disney Research, ETH Zurich and Dartmouth College, however, makes it possible to simulate the appearance of a variety of grains or their mixtures, and to do so with unprecedented computational efficiency.
Thu, 08 Dec 2016 00:00:00 ESTA groundbreaking contact lens therapy has potential to impact the fast-growing issue of myopia (nearsightedness) among children. CooperVision Senior Manager of Clinical Research Paul Chamberlain shared two-year interim results from a clinical trial assessing a specially-designed, dual-focus myopia control one-day soft contact lens in reducing the rate of progression of juvenile-onset myopia. His results show that the therapy is effective in slowing myopia progression in children by 59 percent over two years.
Thu, 08 Dec 2016 00:00:00 ESTWhen it comes to second generation biofuels, Washington State University research shows that consumers are willing to pay a premium of approximately 11 percent over conventional fuel.
Thu, 08 Dec 2016 00:00:00 ESTType 1 diabetes patients with elevated albumin in their urine had three times the risk of life-threatening kidney and cardiac disease as those with normal levels, according to researchers at the University of Colorado Anschutz Medical Campus.
Thu, 08 Dec 2016 00:00:00 ESTHow often women in heterosexual couples desire sex depends on how committed the relationship is and what type of birth control the woman uses.
Thu, 08 Dec 2016 00:00:00 ESTRecently, a new polarization-dipole azimuth-based super-resolution technique has been proposed by a group of researchers in Peking University (China), Tsinghua University (China), and University of Technology Sydney (Australia). It not only provides a new dimension for super-resolution, but also provides a timely solution to a recent hot debate in the field.
Thu, 08 Dec 2016 00:00:00 ESTA team of researchers from the University of Pittsburgh has found that insomnia is highly prevalent in adults with asthma and is also associated with worse asthma control, depression and anxiety symptoms and other quality of life and health issues. The study results are published in the current issue of the journal CHEST.
Thu, 08 Dec 2016 00:00:00 ESTA new study by Burke Museum and University of Washington paleontologists describes an early marsupial relative called Didelphodon vorax that lived alongside ferocious dinosaurs and had, pound-for-pound, the strongest bite force of any mammal ever recorded.
Thu, 08 Dec 2016 00:00:00 ESTHummingbirds' ability to accelerate and turn diminishes at high altitudes, but it isn't a lack of oxygen to the body that limits the birds' performance -- it's physics. University of British Columbia researchers captured male adult hummingbirds and transported them to the White Mountain Research Centre in California. The center, situated at 3,800 metres (12,500 feet), allowed the researchers to evaluate the birds' ability to accelerate and turn, and compare them to baselines gathered closer to sea level.
Thu, 08 Dec 2016 00:00:00 ESTMost animals we study have adult-like bodies early in their development. But researchers at Stanford's Hopkins Marine Station have found that certain marine worms live for months as little more than a head.
Thu, 08 Dec 2016 00:00:00 ESTA new study shows the expansion of mobile money helped bring hundreds of thousands of Kenyans out poverty, especially those in female-headed households. The study, published in Science, examined how M-PESA, Kenya's text message-based payments system, spread across the country over six years. The researchers estimate that the expansion of M-PESA lifted 194,000 households, or 2 percent of households in the country, above the poverty line, partly driven by women's access to the technology.
Thu, 08 Dec 2016 00:00:00 ESTResearchers have made a major discovery about how cells control when to divide -- representing a step forward in scientists' understanding of one of the most fundamental processes of life.
Thu, 08 Dec 2016 00:00:00 ESTWhat will happen to Earth when, in a few billion years' time, the sun is a hundred times bigger than it is today? Using the most powerful radio telescope in the world, an international team of astronomers has set out to look for answers in the star L2 Puppis. Five billion years ago, this star was very similar to the sun as it is today.
Thu, 08 Dec 2016 00:00:00 ESTBacterial resistance does not come just through adaptation to antibiotics, sometimes the bacteria simply go to sleep. An international team of researchers is looking at compounds that attack bacteria's ability to go dormant and have found the first oxygen-sensitive toxin antitoxin system.
Thu, 08 Dec 2016 00:00:00 ESTResearchers cracked the complete genetic code of individual cells in healthy and diseased human lung tissues to find potential new molecular targets for diagnosing and treating the lethal lung disease Idiopathic Pulmonary Fibrosis (IPF). A team of scientists from Cincinnati Children's Hospital Medical Center, in collaboration with investigators at Cedars-Sinai Medical Center in Los Angeles, publish their findings Dec. 8 in the Journal of Clinical Investigation Insights (JCI Insights).
Thu, 08 Dec 2016 00:00:00 ESTETH researchers have used the simplest approach yet to produce artificial beta cells from human kidney cells. Like their natural model, the artificial cells act as both sugar sensors and insulin producers.
Thu, 08 Dec 2016 00:00:00 ESTAt TU Wien, it was possible to create a nanoscale optical element that regulates the flow of light particles at the intersection of two glass fibers like a roundabout. A single atom was used to control the light paths.
Thu, 08 Dec 2016 00:00:00 ESTPets can help people manage their long-term mental health conditions, according to research published in the open access journal BMC Psychiatry.
Thu, 08 Dec 2016 00:00:00 ESTNew preclinical evidence was put forward by investigators in a series of presentations at the recent meeting of the American College of Neuropsychopharmacology suggest that the a metabolite of ketamine can produce antidepressant-like effects in a mouse model of depression. The metabolite is produced when ketamine is broken down in the body. This finding may lead to further research to better understand ketamine's efficacy in depression and its potential side effects.
Thu, 08 Dec 2016 00:00:00 ESTReport in The Journal of Molecular Diagnostics describes a biomarker, PITX2 DNA methylation, which is capable of distinguishing cancerous tissue from non-cancerous tissue and predicting the risk of cancer recurrence using only small amounts of tissue obtained from core needle biopsies.
Thu, 08 Dec 2016 00:00:00 ESTResearchers find a bacterium 1,000 feet underground (called Paenibacillus) that is resistant to 18 different antibiotics and uses identical methods of defense as similar species found in soils. The scientists identified five novel pathways that were of potential clinical concern.
Thu, 08 Dec 2016 00:00:00 ESTA tumor in a 255-million-year-old mammalian ancestor called a gorgonopsian is detailed in a new research letter published online by JAMA Oncology.
Thu, 08 Dec 2016 00:00:00 ESTA small, preliminary study has found an abnormality involving the retina that may account for altered vision in regular cannabis users. The results are published online by JAMA Ophthalmology.
Thu, 08 Dec 2016 00:00:00 ESTResults of the largest Canadian clinical trial to date comparing standard treatment for locally advanced squamous cell head and neck cancer with an experimental treatment did not show the new treatment is superior.
Thu, 08 Dec 2016 00:00:00 ESTPaleontologists at the University of Washington report that an extinct mammal relative harbored a benign tumor in its jaw made up of miniature, tooth-like structures. The tumor, a compound odontoma, is common to mammals today. But this animal lived 255 million years ago, before mammals even existed.
Thu, 08 Dec 2016 00:00:00 ESTA new study in JAMA Oncology finds that the presence of particular antibodies of human papillomavirus in blood serum are reliable indicators of five-year head and neck cancer survival.
Thu, 08 Dec 2016 00:00:00 ESTBreast cancer cells break away and spread to other parts of the body relatively late on in breast tumor development, an international team of scientists has shown. The research, jointly led by Dr. Peter Van Loo at the Francis Crick Institute, could help refine cancer therapy and is published in the journal Genome Biology.
Thu, 08 Dec 2016 00:00:00 ESTNew research proves that e-cigarette aerosol droplets are effectively delivered to cell surfaces in lab-based biological tests. There have been several studies comparing the impact of e-cigarette vapor with that of cigarette smoke on cellular models. In order to be confident in the results, it is necessary to demonstrate that the aerosol is effectively delivered to the cells used in these tests.
Thu, 08 Dec 2016 00:00:00 ESTIn a new study published today in the journal PLOS ONE, a team of researchers led by King's College London have successfully developed a method that more accurately identifies those obese women at high risk of gestational diabetes, than what is currently being used.
Thu, 08 Dec 2016 00:00:00 ESTA new report by leaders in computational methods and reproducibility lays out recommendations for ways researchers, institutions, agencies and journal publishers can work together to standardize sharing of data sets and software code. The paper 'Enhancing reproducibility for computational methods' appears in the journal Science.
Thu, 08 Dec 2016 00:00:00 ESTEvolution is working hard to rescue some urban fish from a lethal, human-altered environment, according to a study led by the University of California, Davis, and published Dec. 9 in the journal Science. Atlantic killifish living in four polluted East Coast estuaries have adapted to levels of highly toxic industrial pollutants that would normally kill them.
Thu, 08 Dec 2016 00:00:00 ESTA professional astrophysicist and an amateur astronomer have teamed up to reveal surprising details about an unusual millisecond pulsar (MSP) binary system comprising one of the fastest-spinning pulsars in our Galaxy and its unique companion star.
Thu, 08 Dec 2016 00:00:00 ESTResearchers have created a highly sensitive and effective sensor out of an unusual combination of materials -- graphene sheets and a commercial polymer known as Silly Putty.
Thu, 08 Dec 2016 00:00:00 ESTTurning the theory of how the human brain perceives time on its head, a novel analysis in mice reveals that dopamine neuron activity plays a key role in judgment of time, slowing down the internal clock.