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RSC - Food Funct. latest articles



RSC - Food Funct. latest articles



Last Build Date: Fri, 27 Apr 2018 06:36:06 Z

Copyright: Copyright (c) The Royal Society of Chemistry
 



Curcumin derivative, WZ35 activates ROS dependent JNK to suppress hepatocellular carcinoma metastasis
Food Funct., 2018, Accepted Manuscript
DOI: 10.1039/C8FO00314A, Paper
Lihua Wang, Lijie Han, Zheying Tao, Zheng Zhu, Lei Han, Zhenfei Yang, Hao Wang, Dandan Dai, Liang Wu, Zhengzhong Yuan, Tongke Chen
Tumor metastasis is the leading cause of cancer death and since the progresses that in elucidating the mechanism of the cancer cell metastasis, which give the hope of severe stage...
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Cocoa procyanidins modulate transcriptional pathways linked to inflammation and metabolism in human dendritic cells
Food Funct., 2018, Accepted Manuscript
DOI: 10.1039/C8FO00387D, Paper
Helene Midttun, Aina Ramsay, Irene Muller-Harvey, Andrew Williams
Foods rich in polyphenols such as procyanidins (PC) have been proposed to have anti-inflammatory properties, and we have previously reported inhibition of lipopolysaccharide (LPS)-induced inflammatory cytokine secretion in human dendritic...
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Microrheology and microstructure of water-in-water emulsions containing sodium caseinate and locust bean gum

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Food Funct., 2018, Advance Article
DOI: 10.1039/C7FO01412K, Paper
Thomas Moschakis, Nikos Chantzos, Costas G. Biliaderis, Eric Dickinson
Employing in situ particle tracking microrheology to clarify the casein-locust bean gum interactions in a w/w emulsion system.
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C-Phycocyanin inhibits hepatic gluconeogenesis and increases glycogen synthesis via activating Akt and AMPK in insulin resistance hepatocytes

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Food Funct., 2018, Advance Article
DOI: 10.1039/C8FO00257F, Paper
Zhiheng Ren, Zhifei Xie, Danni Cao, Mufeng Gong, Lei Yang, Zhu Zhou, Yu Ou
The mechanism of C-PC in improving glucose homoeostasis is to activate the IRS/PI3 K/Akt and SIRT1/LKB1/AMPK signaling pathway in insulin resistant hepatocytes.
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Black pepper-based beverage induced appetite-suppressing effects without altering postprandial glycaemia, gut and thyroid hormones or gastrointestinal well-being: a randomized crossover study in healthy subjects

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Food Funct., 2018, Advance Article
DOI: 10.1039/C7FO01715D, Paper
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Yoghatama Cindya Zanzer, Merichel Plaza, Anestis Dougkas, Charlotta Turner, Elin Ostman
Pleiotropic effects of spices on health, particularly on glucose metabolism and energy regulation, deserve further clinical investigation into their efficacy.
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Comparative study of EPA-Enriched Ethanolamine plasmalogen and EPA-Enriched Phosphatidylethanolamine on A[small beta]42 induced cognitive deficiency in a rat model of Alzheimer's Disease
Food Funct., 2018, Accepted Manuscript
DOI: 10.1039/C8FO00643A, Paper
Hongxia Che, Qian Li, Tiantian Zhang, Lin Ding, Lingyu Zhang, Hao-hao Shi, Teruyoshi Yanagita, Changhu Xue, Yaoguang Chang, Yuming Wang
Ethanolamine plasmalogen (pPE), a major phospholipid in neuronal membranes, is specifically reduced in postmortem brains from patients with Alzheimer's disease (AD). The purpose of the present study was to compare...
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Expression of concern: ZnO nanoparticles affect intestinal function in an in vitro model
Food Funct., 2018, 9,2533-2533
DOI: 10.1039/C8FO90012D, Expression of Concern
(image) Open Access
Philippa Hughes
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Ginnalin A from Kujin tea (Acer tataricum subsp. ginnala) exhibits a colorectal cancer chemoprevention effect via activation of the Nrf2/HO-1 signaling pathway

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Food Funct., 2018, Advance Article
DOI: 10.1039/C8FO00054A, Paper
Wu Bi, Chun-nian He, Xiao-xiao Li, Liu-ying Zhou, Rui-jie Liu, Sai Zhang, Guo-qing Li, Zhu-chu Chen, Peng-fei Zhang
Ginnalin A may activate the Nrf2 signaling pathway through the upregulation of p62 and the inhibition of Keap1 to exert a cancer chemoprevention effect.
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Wheat bran with enriched gamma-aminobutyric acid attenuates glucose intolerance and hyperinsulinemia induced by a high-fat diet

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Food Funct., 2018, Advance Article
DOI: 10.1039/C8FO00331A, Paper
Wenting Shang, Xu Si, Zhongkai Zhou, Padraig Strappe, Chris Blanchard
In this study, the level of gamma-aminobutyric acid in wheat bran was increased to be six times higher and the new bran had a greater capacity for weight control in high-fat diet than untreated bran.
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Black rice anthocyanin-rich extract and rosmarinic acid, alone and in combination, protect against DSS-induced colitis in mice

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Food Funct., 2018, Advance Article
DOI: 10.1039/C7FO01490B, Paper
Lei Zhao, Yali Zhang, Guorong Liu, Shuai Hao, Chengtao Wang, Yong Wang
Black rice anthocyanin-rich extract and rosmarinic acid ameliorated DSS-induced colitis in mice by down-regulating pro-inflammatory mediators and exhibited an additive interaction in reducing MPO, NO and the expression of some pro-inflammatory mediators.
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Impact of different sequences of mechanical and thermal processing on the rheological properties of Porphyridium cruentum and Chlorella vulgaris as functional food ingredients

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Food Funct., 2018, 9,2433-2446
DOI: 10.1039/C8FO00261D, Paper
Tom M. M. Bernaerts, Agnese Panozzo, Katrien A. F. Verhaegen, Lore Gheysen, Imogen Foubert, Paula Moldenaers, Marc E. Hendrickx, Ann M. Van Loey
Different processing sequences result in specific rheological properties of these microalgae as functional food ingredients.
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Multiple mechanisms applied by Lactobacillus pentosus AT6 to mute the lethal effects of Salmonella in a mouse model

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Food Funct., 2018, Advance Article
DOI: 10.1039/C7FO01858D, Paper
Junsheng Liu, Zhennan Gu, Wenwei Lu, Diangeng Hu, Xi Zhao, Hongxuan Huang, Hao Zhang, Jianxin Zhao, Wei Chen
Lactobacillus pentosus AT6 mutes the lethal effects of Salmonella via multiple mechanisms.
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Casein glycomacropeptide hydrolysates inhibit PGE2 production and COX2 expression in LPS-stimulated RAW 264.7 macrophage cells via Akt mediated NF-[small kappa]B and MAPK pathways

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Food Funct., 2018, 9,2524-2532
DOI: 10.1039/C7FO01989K, Paper
Tiange Li, Dongxiao Gao, Min Du, Xue Cheng, Xueying Mao
A casein glycomacropeptide hydrolysate (GMPH) was found to possess inhibitory activity against lipopolysaccharide (LPS)-induced inflammatory response in our previous study.
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Calycosin directly improves perivascular adipose tissue dysfunction by upregulating the adiponectin/AMPK/eNOS pathway in obese mice

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Food Funct., 2018, 9,2409-2415
DOI: 10.1039/C8FO00328A, Paper
Fang Han, Kai Li, Ruiyan Pan, Wenjie Xu, Xue Han, Ningning Hou, Xiaodong Sun
Calycosin improves perivascular adipose tissue dysfunction.
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Bioaccessible selenium sourced from Se-rich mustard cake facilitates protection from TBHP induced cytotoxicity in melanoma cells

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Food Funct., 2018, 9,1998-2004
DOI: 10.1039/C7FO01644A, Communication
Sumit K. Jaiswal, Ranjana Prakash, K. Sandeep Prabhu, N. Tejo Prakash
Bioaccessible selenium inhibits TBHP toxicity in melanoma cells.
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Ultrasonicated Lespedeza cuneata extract prevents TNF-[small alpha]-induced early atherosclerosis in vitro and in vivo

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Food Funct., 2018, 9,2090-2101
DOI: 10.1039/C7FO01666B, Paper
Su Jeong Ha, Jangho Lee, Kyung-Mo Song, Young Ho Kim, Nam Hyouck Lee, Young-Eon Kim, Sung Keun Jung
This study evaluated the use of ultrasonication to extract Lespedeza cuneata as a potential nutraceutical for preventing vascular inflammation.
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Dietary fish oil ameliorates adipose tissue dysfunction in insulin-resistant rats fed a sucrose-rich diet improving oxidative stress, peroxisome proliferator-activated receptor [gamma] and uncoupling protein 2

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Food Funct., 2018, 9,2496-2507
DOI: 10.1039/C7FO01993A, Paper
Dante Selenscig, Maria del Rosario Ferreira, Adriana Chicco, Yolanda B. Lombardo
Dietary fish oil exerts beneficial effects on the adipose tissue dysfunction in dyslipemic insulin-resistant rats fed a sucrose-rich diet.
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Assessment of endocrine disruption potential of essential oils of culinary herbs and spices involving glucocorticoid, androgen and vitamin D receptors

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Food Funct., 2018, 9,2136-2144
DOI: 10.1039/C7FO02058A, Paper
Iveta Bartonkova, Zdenek Dvorak
Essential oils of culinary herbs and species influence transcriptional activities of nuclear receptor VDR and steroid hormones receptors AR and GR.
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Prebiotic effects of resistant starch from purple yam (Dioscorea alata L.) on the tolerance and proliferation ability of Bifidobacterium adolescentis in vitro

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Food Funct., 2018, 9,2416-2425
DOI: 10.1039/C7FO01919J, Paper
Tao Li, Lei Chen, Jianbo Xiao, Fengping An, Cheng Wan, Hongbo Song
The in vitro prebiotic effects of resistant starch (RS), prepared by different treatments from purple yam, on Bifidobacterium adolescentis were investigated.
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Beneficial effects of Cirsium japonicum var. maackii on menopausal symptoms in ovariectomized rats

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Food Funct., 2018, 9,2480-2489
DOI: 10.1039/C7FO01258F, Paper
Jun Yeon Park, Hwayoung Yun, Jeyun Jo, Ji Yun Baek, Sang Cheon Lee, Yu Jin Choi, Jae Suk Shim, Hyun Jin Choi, Sanghyun Lee, Ki Sung Kang
Cirsium japonicum var. maackii exerted beneficial effects in a rat model of menopause.
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High internal phase emulsion (HIPE)-templated biopolymeric oleofilms containing an ultra-high concentration of edible liquid oil

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Food Funct., 2018, 9,1993-1997
DOI: 10.1039/C7FO01945A, Communication
Wahyu Wijaya, Paul Van der Meeren, Koen Dewettinck, Ashok R. Patel
Oleofilms are produced via casting and drying of HIPEs stabilized using sodium caseinate (SC): alginate (ALG) complexes.
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Ultrasmall fluorescent nanoparticles derived from roast duck: their physicochemical characteristics and interaction with human serum albumin

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Food Funct., 2018, 9,2490-2495
DOI: 10.1039/C8FO00178B, Paper
Shuang Cong, Jingran Bi, Xunyu Song, Chenxu Yu, Mingqian Tan
Fluorescent nanoparticles (FNPs) produced from roast meat have drawn widespread attention due to their potential hazards to human health.
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Paeoniflorin prevents endoplasmic reticulum stress-associated inflammation in lipopolysaccharide-stimulated human umbilical vein endothelial cells via the IRE1[small alpha]/NF-[small kappa]B signaling pathway

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Food Funct., 2018, 9,2386-2397
DOI: 10.1039/C7FO01406F, Paper
Juan Chen, Minghua Zhang, Maomao Zhu, Junfei Gu, Jie Song, Li Cui, Dan Liu, Qing Ning, Xiaobin Jia, Liang Feng
Paeoniflorin has inhibitory effect on ER stress-associated vascular inflammation.
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In vitro lipid digestion in raw and roasted hazelnut particles and oil bodies

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Food Funct., 2018, 9,2508-2516
DOI: 10.1039/C8FO00389K, Paper
Edoardo Capuano, Nicoletta Pellegrini, Eleni Ntone, Constantinos V. Nikiforidis
The impact of roasting and food structure on digestion of hazelnut particles and oil bodies has been thoroughly investigated.
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Raspberry anthocyanin consumption prevents diet-induced obesity by alleviating oxidative stress and modulating hepatic lipid metabolism

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Food Funct., 2018, 9,2112-2120
DOI: 10.1039/C7FO02061A, Paper
Tao Wu, Lu Yang, Xueqi Guo, Min Zhang, Rui Liu, Wenjie Sui
Evidence indicates that raspberries have beneficial effects on chronic diseases.
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Modulation of whey protein-kappa carrageenan hydrogel properties via enzymatic protein modification

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Food Funct., 2018, 9,2313-2319
DOI: 10.1039/C7FO01510K, Paper
Michael J. Selig, B. N. Dar, Arkaye Kierulf, Raheleh Ravanfar, Syed S. H. Rizvi, Alireza Abbaspourrad
Treatment of whey protein isolate (WPI) in heated [small kappa]-carrageenan (KC) slurries with protease and/or transglutaminase modulates the appearance and strength of hydrogels formed upon cooling.
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Anti-anemia effects of ginsenoside Rk3 and ginsenoside Rh4 on mice with ribavirin-induced anemia

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Food Funct., 2018, 9,2447-2455
DOI: 10.1039/C8FO00368H, Paper
Bo Wei, Zhiguang Duan, Chenhui Zhu, Jianjun Deng, Daidi Fan
Ginsenoside Rk3 and ginsenoside Rh4 stimulate hematopoiesis and show excellent anti-anemia effects via the combined effects of different related cytokines.
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Antinutritional factors and hypocholesterolemic effect of wild apricot kernel (Prunus armeniaca L.) as affected by detoxification

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Food Funct., 2018, 9,2121-2135
DOI: 10.1039/C8FO00044A, Paper
Beenu Tanwar, Rajni Modgil, Ankit Goyal
Detoxification treatment substantially reduced antinutritional factors along with the complete removal of hydrocyanic acid from wild (bitter) apricot kernel and improved the hypocholesterolemic effect in male Wistar albino rats.
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The effect of Lactobacillus acidophilus and Lactobacillus casei on the in vitro bioaccessibility of flaxseed lignans (Linum usitatissimum L.)

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Food Funct., 2018, 9,2426-2432
DOI: 10.1039/C8FO00390D, Paper
O. Munoz, C. Fuentealba, D. Ampuero, F. Figuerola, A. M. Estevez
L. casei slightly improves the bioaccessibility of SDG for whole flaxseed digestion.
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The inhibitory effect of Manuka honey on human colon cancer HCT-116 and LoVo cell growth. Part 1: the suppression of cell proliferation, promotion of apoptosis and arrest of the cell cycle

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Food Funct., 2018, 9,2145-2157
DOI: 10.1039/C8FO00164B, Paper
Sadia Afrin, Francesca Giampieri, Massimiliano Gasparrini, Tamara Y. Forbes-Hernandez, Danila Cianciosi, Patricia Reboredo-Rodriguez, Adolfo Amici, Jose L. Quiles, Maurizio Battino
Manuka honey suppresses human colon cancer cell proliferation through the promotion of apoptosis.
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The inhibitory effect of Manuka honey on human colon cancer HCT-116 and LoVo cell growth. Part 2: Induction of oxidative stress, alteration of mitochondrial respiration and glycolysis, and suppression of metastatic ability

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Food Funct., 2018, 9,2158-2170
DOI: 10.1039/C8FO00165K, Paper
Sadia Afrin, Francesca Giampieri, Massimiliano Gasparrini, Tamara Y. Forbes-Hernandez, Danila Cianciosi, Patricia Reboredo-Rodriguez, Piera Pia Manna, Jiaojiao Zhang, Jose L. Quiles, Maurizio Battino
Manuka honey induces chemopreventive effects.
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Influence of Cassia grandis galactomannan on the properties of sponge cakes: a substitute for fat

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Food Funct., 2018, 9,2456-2468
DOI: 10.1039/C7FO01864A, Paper
Francisca Joyce E. T. Andrade, Priscilla B. S. de Albuquerque, Jose Roberto P. C. de Seixas, George S. Feitoza, Wilson Barros Junior, Antonio A. Vicente, Maria das Gracas Carneiro-da-Cunha
Here we have proposed to evaluate potential replacers of fat in sponge cake formulations.
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Quercetin-3-O-[small alpha]-L-arabinopyranoside protects against retinal cell death via blue light-induced damage in human RPE cells and Balb-c mice

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Food Funct., 2018, 9,2171-2183
DOI: 10.1039/C7FO01958K, Paper
Jun Kim, Hong Lan Jin, Dae Sik Jang, Kwang Won Jeong, Se-Young Choung
Age-related macular degeneration (AMD) is a chronic degenerative disease that can lead to visual loss and blindness in the elderly.
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Citrus medica: nutritional, phytochemical composition and health benefits - a review

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Food Funct., 2018, 9,1978-1992
DOI: 10.1039/C7FO02035J, Review Article
Navnidhi Chhikara, Ragni Kour, Sundeep Jaglan, Pawan Gupta, Yogesh Gat, Anil Panghal
Health benefits and products of Citrus medica.
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Dietary impact on esophageal cancer in humans: a review

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Food Funct., 2018, 9,1967-1977
DOI: 10.1039/C7FO01908D, Review Article
Rachna Khosla Sardana, Navnidhi Chhikara, Beenu Tanwar, Anil Panghal
Foods and the risk of esophageal cancer.
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Safety considerations of plant polysaccharides for food use: a case study on phenolic-rich softwood galactoglucomannan extract

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Food Funct., 2018, 9,1931-1943
DOI: 10.1039/C7FO01425B, Review Article
(image) Open Access
Leena Pitkanen, Marina Heinonen, Kirsi S. Mikkonen
A growing population and concern over the sufficiency of natural resources for feeding this population have motivated researchers and industries to search for alternative and complementary sources of food ingredients and additives.
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Networks of micronized fat crystals grown under static conditions

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Food Funct., 2018, 9,2102-2111
DOI: 10.1039/C8FO00148K, Paper
T. Nikolaeva, R. den Adel, E. Velichko, W. G. Bouwman, D. Hermida-Merino, H. Van As, A. Voda, J. van Duynhoven
Dispersions of micronized fat crystals (MFCs) in oil form a weak-interaction network organized by crystal aggregates in a continuous net of crystalline nanoplatelets.
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Dietary supplementation with omega-3 polyunsaturated fatty acid-rich oils protects against visible-light-induced retinal damage in vivo

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Food Funct., 2018, 9,2469-2479
DOI: 10.1039/C7FO01168G, Paper
Qianchun Deng, Yong Wang, Chengtao Wang, Baoping Ji, Renhuai Cong, Lei Zhao, Peng Chen, Xixi Zang, Feng Lu, Fei Han, Fenghong Huang
Dietary [small omega]-3 PUFA-rich oils protect against visible-light-induced retinal damage.
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Long-chain polyunsaturated fatty acids and extensively hydrolyzed casein-induced browning in a Ucp-1 reporter mouse model of obesity

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Food Funct., 2018, 9,2362-2373
DOI: 10.1039/C7FO01835E, Paper
Liufeng Mao, Jiwen Lei, Marieke H. Schoemaker, Bingxiu Ma, Yan Zhong, Tim T. Lambers, Eric A. F. Van Tol, Yulai Zhou, Tao Nie, Donghai Wu
Browning in adipose tissues, which can be affected by diet, may mitigate the detrimental effects of adiposity and improve longer-term metabolic health.
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Upregulating mTOR/ERK signaling with leonurine for promoting angiogenesis and tissue regeneration in a full-thickness cutaneous wound model

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Food Funct., 2018, 9,2374-2385
DOI: 10.1039/C7FO01289F, Paper
Chenggui Wang, Zengjie Zhang, Tianzhen Xu, Yiting Lou, Qingqing Wang, Haiming Jin, Lilian Zhang, Yongzeng Feng, Huazi Xu, Cong Mao
LN promoted the angiogenesis of endothelial cells by activating the mTOR/ERK pathway, and efficiently enhanced the wound-healing process in vivo.
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Phenethyl isothiocyanate in combination with dibenzoylmethane inhibits the androgen-independent growth of prostate cancer cells

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Food Funct., 2018, 9,2398-2408
DOI: 10.1039/C7FO01983A, Paper
Huarong Huang, Yan He, Lanyue Zhang, Hongping Xiang, Dongli Li, Wenfeng Liu, Xue-Tao Xu, Susan Goodin, Kun Zhang, Xi Zheng
This study investigates the inhibitory effect of PEITC and DBM in combination on the progression of androgen-dependent VCaP prostate tumors to androgen independence.
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Application of pulsed electric fields to tomato fruit for enhancing the bioaccessibility of carotenoids in derived products

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Food Funct., 2018, 9,2282-2289
DOI: 10.1039/C7FO01857F, Paper
(image) Open Access
Sandra Gonzalez-Casado, Olga Martin-Belloso, Pedro Elez-Martinez, Robert Soliva-Fortuny
The application of pulsed electric fields (PEFs) to whole tomatoes is proposed as a pre-processing treatment to obtain purees with high health-related properties.
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Octahydrocurcumin, a final hydrogenated metabolite of curcumin, possesses superior anti-tumor activity through induction of cellular apoptosis

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Food Funct., 2018, 9,2005-2014
DOI: 10.1039/C7FO02048A, Paper
Zhenbiao Zhang, Dandan Luo, Jianhui Xie, Guosheng Lin, Jiangtao Zhou, Weihai Liu, Huilin Li, Tiegang Yi, Ziren Su, Jianping Chen
Curcumin (CUR), a promising natural-occurring dietary compound for the treatment of hepatocellular carcinoma (HCC), was closely associated with its metabolite.
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The chemical structure and anti-aging bioactivity of an acid polysaccharide obtained from rose buds

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Food Funct., 2018, 9,2300-2312
DOI: 10.1039/C8FO00206A, Paper
Yun Tang, Zhen-Yuan Zhu, Yao Liu, Huiqing Sun, Qiao-Ying Song, Yongmin Zhang
An acid polysaccharide, named R-PL, was extracted from rose buds by hot water (80 [degree]C) extraction and purified by Sephadex G-200.
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Pretreatment with dihydroquercetin, a dietary flavonoid, protected against concanavalin A-induced immunological hepatic injury in mice and TNF-[small alpha]/ActD-induced apoptosis in HepG2 cells

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Food Funct., 2018, 9,2341-2352
DOI: 10.1039/C7FO01073G, Paper
Jiajie Chen, Xu Sun, Tingting Xia, Qiqi Mao, Liang Zhong
We have previously demonstrated the hepatoprotective effect of dihydroquercetin (DHQ) against concanavalin A (Con A)-induced immunological hepatic injury in mice.
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Bioactive peptide isolated from casein phosphopeptides promotes calcium uptake in vitro and in vivo

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Food Funct., 2018, 9,2251-2260
DOI: 10.1039/C7FO01709J, Paper
Guo Liu, Shengwei Sun, Baoyan Guo, Benchun Miao, Zhen Luo, Zumeng Xia, Danyang Ying, Fei Liu, Bin Guo, Jian Tang, Yong Cao, Jianyin Miao
A monomeric peptide isolated from casein phosphopeptides promoted calcium uptake in cells via the transcellular pathway and was beneficial for bone calcification in rats.
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The impact of galactooligosaccharides on the bioaccessibility of sterols in a plant sterol-enriched beverage: adaptation of the harmonized INFOGEST digestion method

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Food Funct., 2018, 9,2080-2089
DOI: 10.1039/C8FO00155C, Paper
Virginia Blanco-Morales, Gabriel Lopez-Garcia, Antonio Cilla, Guadalupe Garcia-Llatas, Reyes Barbera, Maria Jesus Lagarda, Luis Manuel Sanchez-Siles, Amparo Alegria
Bioaccessibility of sterols in milk-based fruit beverages: comparison of two in vitro digestions.
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Citrus reticulata peel oil inhibits non-small cell lung cancer cell proliferation in culture and implanted in nude mice

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Food Funct., 2018, 9,2290-2299
DOI: 10.1039/C7FO01912B, Paper
Maria Agustina Castro, Boris Rodenak-Kladniew, Adriana Massone, Monica Polo, Margarita Garcia de Bravo, Rosana Crespo
Mandarin peel oil exerts an antiproliferative effect on in vitro and in vivo human tumour cells without toxicity effects.
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Protective effects of Coptis chinensis inflorescence extract and linarin against carbon tetrachloride-induced damage in HepG2 cells through the MAPK/Keap1-Nrf2 pathway

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Food Funct., 2018, 9,2353-2361
DOI: 10.1039/C8FO00078F, Paper
Bing-Xin Ma, Xiao-Shan Meng, Jing Tong, Lan-Lan Ge, Gao Zhou, You-Wei Wang
C. chinensis inflorescence extract and linarin could reverse the hepatotoxicity induced by CCl4 through the MAPK/Keap1-Nrf2 pathway.
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Evaluation of the nutrition and function of cow and goat milk based on intestinal microbiota by metagenomic analysis

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Food Funct., 2018, 9,2320-2327
DOI: 10.1039/C7FO01780D, Paper
Zhaoxia Wang, Shuaiming Jiang, Chenchen Ma, Dongxue Huo, Qiannan Peng, Yuyu Shao, Jiachao Zhang
A high-throughput 16S rRNA sequencing technology was applied to study changes of the intestinal microbiota in mice after the administration of cow and goat milk. We show a correlation between the gut microbiota and the nutrients in milk.
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Phytol stimulates the browning of white adipocytes through the activation of AMP-activated protein kinase (AMPK) [small alpha] in mice fed high-fat diet

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Food Funct., 2018, 9,2043-2050
DOI: 10.1039/C7FO01817G, Paper
Fenglin Zhang, Wei Ai, Xiaoquan Hu, Yingying Meng, Cong Yuan, Han Su, Lina Wang, Xiaotong Zhu, Ping Gao, Gang Shu, Qingyan Jiang, Songbo Wang
In vivo and in vitro studies show that phytol stimulates the browning of mice iWAT and formation of brown-like adipocytes in the differentiated 3T3-L1 through the activation of the AMPK[small alpha] signaling pathway.
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Water soluble compounds of Rosmarinus officinalis L. improve the oxidative and inflammatory states of rats with adjuvant-induced arthritis

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Food Funct., 2018, 9,2328-2340
DOI: 10.1039/C7FO01928A, Paper
Geferson de Almeida Goncalves, Anacharis B. de Sa-Nakanishi, Jurandir F. Comar, Livia Bracht, Maria Ines Dias, Lillian Barros, Rosane M. Peralta, Isabel C. F. R. Ferreira, Adelar Bracht
Water soluble compounds of rosemary leaves attenuate oxidative stress and inflammation in arthritic rats.
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Broad bean (Vicia faba L.) pods: a rich source of bioactive ingredients with antimicrobial, antioxidant, enzyme inhibitory, anti-diabetic and health-promoting properties

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Food Funct., 2018, 9,2051-2069
DOI: 10.1039/C8FO00055G, Paper
Faiza Mejri, Slimen Selmi, Alice Martins, Haifa benkhoud, Tarek Baati, Hedia Chaabane, Leila Njim, Maria L. M. Serralheiro, Amelia P. Rauter, Karim Hosni
Broad bean pods have been proven to be a functional food with promising in vitro and in vivo biological activities.
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Unsaponifiable fraction isolated from grape (Vitis vinifera L.) seed oil attenuates oxidative and inflammatory responses in human primary monocytes

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Food Funct., 2018, 9,2517-2523
DOI: 10.1039/C8FO00063H, Paper
Maria C. Millan-Linares, Beatriz Bermudez, Maria E. Martin, Ernesto Munoz, Rocio Abia, Francisco Millan, Francisco J. G. Muriana, Sergio Montserrat-de la Paz
Grape seed oil has significant potential for the management of inflammatory and oxidative conditions.
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Whole-grain oats (Avena sativa L.) as a carrier of lactic acid bacteria and a supplement rich in angiotensin I-converting enzyme inhibitory peptides through solid-state fermentation

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Food Funct., 2018, 9,2270-2281
DOI: 10.1039/C7FO01578J, Paper
Han Wu, Xin Rui, Wei Li, Yu Xiao, Jianzhong Zhou, Mingsheng Dong
A novel strategy was found to develop whole-grain oats as a probiotic carrier and a nutraceutical supplement targeting hypertension.
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Chitosan binding onto the epigallocatechin-loaded ferritin nanocage enhances its transport across Caco-2 cells

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Food Funct., 2018, 9,2015-2024
DOI: 10.1039/C8FO00097B, Paper
Rui Yang, Jing Tian, Desheng Wang, Chris Blanchard, Zhongkai Zhou
The binding of chitosan to epigallocatechin-encapsulated ferritin enhances epigallocatechin transport across Caco-2 cells through the transferrin receptor 1 (TfR1)-mediated absorption pathway.
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Modulation of the bitterness of pea and potato proteins by a complex coacervation method

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Food Funct., 2018, 9,2261-2269
DOI: 10.1039/C7FO01849E, Paper
Benjamin Zeeb, Merve Yavuz-Duzgun, Johannes Dreher, Jacob Evert, Timo Stressler, Lutz Fischer, Beraat Ozcelik, Jochen Weiss
The incorporation of novel plant-based proteins into foods is often challenging due to an unacceptable bitter sensation.
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Evaluating the effects of IADHFL on inhibiting DPP-IV activity and expression in Caco-2 cells and contributing to the amount of insulin released from INS-1 cells in vitro

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Food Funct., 2018, 9,2240-2250
DOI: 10.1039/C7FO01950E, Paper
Chi Zhang, Huaigao Liu, Shangwu Chen, Yongkang Luo
Intact IADHFL was observed after simulated gastrointestinal digestion and part of the peptide was hydrolyzed into IADHF without reducing its DPP-IV inhibitory activity.
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Nanoencapsulation of docosahexaenoic acid (DHA) using a combination of food grade polymeric wall materials and its application for improvement in bioavailability and oxidative stability

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Food Funct., 2018, 9,2213-2227
DOI: 10.1039/C7FO01391D, Paper
Harmanpreet Singh, Chateshwar Kumar, Narpinder Singh, Surinder Paul, Subheet Kumar Jain
Developed nanoencapsulated DHA powder of microalgae oil with improved oxidative stability and bioavailability in brain using combination of wall materials.
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Apoptosis effects of imperatorin on synoviocytes in rheumatoid arthritis through mitochondrial/caspase-mediated pathways

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Food Funct., 2018, 9,2070-2079
DOI: 10.1039/C7FO01748K, Paper
Ke-feng Zhai, Hong Duan, Yuan Chen, Ghulam Jilany Khan, Wen-gen Cao, Gui-zhen Gao, Ling-ling Shan, Zhao-jun Wei
Rheumatoid arthritis (RA) is a systemic chronic inflammatory disease associated with a potential imbalance between the growth and death of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs).
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n-3 polyunsaturated fatty acids prevent D-galactose-induced cognitive deficits in prediabetic rats

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Food Funct., 2018, 9,2228-2239
DOI: 10.1039/C8FO00074C, Paper
Yu-Ru Guo, Hsiu-Chuan Lee, Yun-Chun Lo, Shao-Chuan Yu, Shih-Yi Huang
Nutritional deficit of n-3 polyunsaturated fatty acids (PUFAs) is closely related to cognitive impairment and depression in later life.
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A comparative study of eicosapentaenoic acid enriched phosphatidylcholine and ethyl ester in improving cognitive deficiency in Alzheimer's disease model rats

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Food Funct., 2018, 9,2184-2192
DOI: 10.1039/C7FO01815K, Paper
Min Wen, Lin Ding, Lingyu Zhang, Peixu Cong, Tiantian Zhang, Jie Xu, Yaoguang Chang, Yuming Wang, Changhu Xue
Molecular mechanisms of EPA-PC and EPA-EE in improving A[small beta]-induced cognitive deficiency in rats.
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Effect of fisetin supplementation on inflammatory factors and matrix metalloproteinase enzymes in colorectal cancer patients

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Food Funct., 2018, 9,2025-2031
DOI: 10.1039/C7FO01898C, Paper
Alireza Farsad-Naeimi, Mohammad Alizadeh, Ali Esfahani, Esmaeil Darvish Aminabad
Promising effects of fisetin on the inflammation status in colorectal cancer.
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The impact of the molecular weight of dextran on formation of whey protein isolate (WPI)-dextran conjugates in fibers produced by needleless electrospinning after annealing

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Food Funct., 2018, 9,2193-2200
DOI: 10.1039/C7FO02041D, Paper
Deniz Turan, Monika Gibis, Gurbuz Gunes, Stefan K. Baier, Jochen Weiss
The conjugation reaction of electrospun fibers of a mixture of whey protein isolate (WPI) and dextran using different molecular weights (40, 70, and 100 kDa) and mixing ratios was studied.
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Fractionation of the more active extracts of Geranium molle L.: a relationship between their phenolic profile and biological activity

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Food Funct., 2018, 9,2032-2042
DOI: 10.1039/C7FO01994G, Paper
V. C. Graca, Maria Ines Dias, Lillian Barros, Ricardo C. Calhelha, P. F. Santos, Isabel C. F. R. Ferreira
Active extracts of Geranium molle L. were fractionated and the fractions were evaluated for their antioxidant activity and cytotoxicity against several human tumor cell lines, and their phenolic profile was determined.
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Xylitol, mannitol and maltitol as potential sucrose replacers in burger buns

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Food Funct., 2018, 9,2201-2212
DOI: 10.1039/C8FO00066B, Paper
Aylin W. Sahin, Claudia Axel, Emanuele Zannini, Elke K. Arendt
Burger buns are a source of added sugar, containing 7-12%, in order to ensure their unique texture and taste.
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Effects of superfoods on risk factors of metabolic syndrome: a systematic review of human intervention trials

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Food Funct., 2018, 9,1944-1966
DOI: 10.1039/C7FO01792H, Review Article
Jose J. van den Driessche, Jogchum Plat, Ronald P. Mensink
A new term was introduced recently to describe foods with additional health benefits: "superfoods", for which up to date no generally accepted definitions exist. Nonetheless, their consumption might contribute to the prevention of metabolic syndrome.
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Retraction: ZnO nanoparticles affect intestinal function in an in vitro model
Food Funct., 2018, Advance Article
DOI: 10.1039/C8FO90013B, Retraction
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Fabiola Moreno-Olivas, Elad Tako, Gretchen J. Mahler
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Characterization of active antiplatelet chemical compositions of edible Citrus limon through ultra-performance liquid chromatography single quadrupole mass spectrometry-based chemometrics

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Food Funct., 2018, Advance Article
DOI: 10.1039/C8FO00403J, Paper
Qian Zhang, Chengning Tan, Liang Cai, Fangbo Xia, Die Gao, Fengqing Yang, Hua Chen, Zhining Xia
UPLC-SQD-MS-based chemometrics was applied for antiplatelet active compounds screening for the first time, and seven potential biomarkers were found in lemon extract.
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Theoretical investigation of the swelling of polysaccharide microgels in sugar solutions
Food Funct., 2018, Accepted Manuscript
DOI: 10.1039/C8FO00452H, Paper
Ruud van der Sman
In this paper, we explain the increased swelling of crosslinked starch by increase of sugar concentration using a modified Flory-Rehner theory. The theory is validated via investigation of the swelling...
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Resveratrol reverses the adverse effects of a diet-induced obese murine model on oocyte quality and zona pellucida softening

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Food Funct., 2018, Advance Article
DOI: 10.1039/C8FO00149A, Paper
Zhenzhen Jia, Zeyang Feng, Lining Wang, Hao Li, Hongyu Wang, Dingqi Xu, Xin Zhao, Daofu Feng, Xizeng Feng
Resveratrol exerts protective effects on ovarian injury, decreased oocyte quality and zona pellucida softening due to obesity.
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Hepatoprotective activity of iridoids, seco-iridoids and analog glycosides from Gentianaceae on HepG2 cells via CYP3A4 induction and mitochondrial pathway

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Food Funct., 2018, Advance Article
DOI: 10.1039/C8FO00168E, Paper
Kang Dai, Xue-Jia Yi, Xian-Ju Huang, Azhar Muhammad, Mei Li, Jun Li, Guang-Zhong Yang, Yue Gao
Gentianaceae herb extracts have been widely used as food additives, teas or medicinal remedies for various diseases and disorders of the human body.
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Dietary compound luteolin inhibits pancreatic cancer growth by targeting BCL-2
Food Funct., 2018, Accepted Manuscript
DOI: 10.1039/C8FO00033F, Paper
Zhimei Li, Yiyuan Zhang, Lixia Chen, Hua Li
Overexpression of prosurvival protein BCL-2 contributes to malignant cells' initiation, progression and resistance to treatment. Agents function as its natural antagonists targeting BCL-2 must provide therapeutic benefit. In SW1990 pancreatic...
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MALDI-TOF-MS characterization of N-linked glycoprotein derived from ginger with ACE inhibitory activity

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Food Funct., 2018, Advance Article
DOI: 10.1039/C8FO00156A, Paper
Wenzhu Zhao, Yuejiao Chen, Siyu Xue, Zhipeng Yu, Hanjie Yu, Jingbo Liu, Jianrong Li, Feng Chen
Herein, the ability of ginger glycoproteins to inhibit the angiotensin-converting enzyme (ACE) is characterized.
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New highlights on the health-improving effects of sulforaphane
Food Funct., 2018, Accepted Manuscript
DOI: 10.1039/C8FO00018B, Review Article
Alfredo Briones-Herrera, Dianelena Eugenio-Perez, Jazmin Gabriela Reyes-Ocampo, Susana Rivera-Mancia, J. Pedraza-Chaverri
In this paper, we review recent evidence about the beneficial effects of sulforaphane (SFN), which is the most studied member of isothiocyanates, on both in vivo and in vitro models...
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Effects of EPA and lipoic acid supplementation on circulating FGF21 and fatty acids profile in overweight/obese women following a hypocaloric diet.
Food Funct., 2018, Accepted Manuscript
DOI: 10.1039/C8FO00355F, Paper
Xavier Escote, Elisa Felix-Soriano, Lucia Gayoso, Ana Elsa Huerta, Maria Antonella Alvarado, D. Ansorena, Iciar Astiasaran, J. Alfredo Martinez, M.J. Moreno-Aliaga
FGF21 has emerged as a key metabolism and energy homeostasis regulator. Dietary supplementation with eicosapentaenoic acid (EPA) and/or [small alpha]-lipoic acid (LIP) has shown beneficial effects on obesity. In this study,...
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Fruit and vegetable consumption and the risk of postmenopausal osteoporosis: A meta-analysis of observational studies
Food Funct., 2018, Accepted Manuscript
DOI: 10.1039/C8FO00205C, Review Article
Wenjie Jiang, Danqing Hu, Lixiao Cheng
The associations for consumption of fruit and vegetable (FV) and the risk of postmenopausal osteoporosis (PMOP) have been a controversial subject. Thus, we carried out a meta-analysis to evaluate the...
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Camel milk attenuates methotrexate-induced kidney injury via activation of PI3K/Akt/eNOS signaling and intervention with oxidative aberrations

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Food Funct., 2018, Advance Article
DOI: 10.1039/C8FO00131F, Paper
Hany H. Arab, Samir A. Salama, Ibrahim A. Maghrabi
Methotrexate (MTX) is a classical chemotherapeutic agent with nephrotoxicity as the most disturbing adverse effect.
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Lactoferrin preserves bone homeostasis by regulating the RANKL/RANK/OPG pathway of osteoimmunology

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Food Funct., 2018, Advance Article
DOI: 10.1039/C8FO00303C, Paper
Fengjiao Fan, Pujie Shi, Meng Liu, Hui Chen, Maolin Tu, Weihong Lu, Ming Du
Lactoferrin preserves bone homeostasis via the osteoimmunology pathway.
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Structural characterization and antitumor activity of a novel Se-polysaccharide from selenium-enriched Cordyceps gunnii

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Food Funct., 2018, Advance Article
DOI: 10.1039/C8FO00027A, Paper
Huiqing Sun, Zhenyuan Zhu, Yali Tang, Yuanyuan Ren, Qiaoying Song, Yun Tang, Yongmin Zhang
Selenium (Se) has been recognized as an essential element.
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[small alpha]-Cyperone inhibits LPS-induced inflammation in BV-2 cells through activation of Akt/Nrf2/HO-1 and suppression of the NF-[small kappa]B pathway

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Food Funct., 2018, Advance Article
DOI: 10.1039/C8FO00057C, Paper
Bingxu Huang, Dewei He, Guangxin Chen, Xin Ran, Wenjin Guo, Xingchi Kan, Wei Wang, Dianfeng Liu, Shoupeng Fu, Juxiong Liu
Accumulating evidence has shown that activated microglia cause inflammatory immune response, which could lead to neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease.
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Isolation, purification, characterization and bioactivities of a glucan from the root of Pueraria lobata

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Food Funct., 2018, Advance Article
DOI: 10.1039/C7FO01921A, Paper
Can Xu, Ningbo Qin, Chunyan Yan, Shumei Wang
The root of Pueraria lobata is considered to be a medicinal and edible herb for the treatment of diabetes, and it has a long history of application in China.
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Soy product consumption and the risk of all-cause, cardiovascular and cancer mortality: a systematic review and meta-analysis of cohort studies

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Food Funct., 2018, Advance Article
DOI: 10.1039/C7FO01622K, Review Article
Nazli Namazi, Parvane Saneei, Bagher Larijani, Ahmad Esmaillzadeh
Currently, the association of soy intake with total- and cause-specific mortality is inconsistent.
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Investigation on effects of mechanical treatments on cellular structure integrity and vitamin C extractability of broccoli (Brassica oleracea L. var. italica) by LF-NMR
Food Funct., 2018, Accepted Manuscript
DOI: 10.1039/C8FO00140E, Paper
Jinxin Yang, Xin JIN, Xiao Dong Chen
Extracting nutrients from plants is an important unit operation in the food and biological industries. The target nutrient is usually spatially distributed throughout the plant tissue. The intact cell wall...
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Fabrication and characterization of complex nanoparticles based on carboxymethyl short chain amylose and chitosan by ionic gelation
Food Funct., 2018, Accepted Manuscript
DOI: 10.1039/C8FO00238J, Paper
Na Ji, Yan Hong, Zhengbiao Gu, Li Cheng, Zhaofeng Li, Caiming Li
We aimed to investigate whether the combination of the modification of short chain amylose (SCA) with chitosan (CS) through electrostatic interaction could be considered as a candidate for oral delivery...
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Effect of nutritional state, aging and high chronic intake of sucrose on brain protein synthesis in rats, Modulation by rutin and other micronutrients
Food Funct., 2018, Accepted Manuscript
DOI: 10.1039/C7FO01953J, Paper
Eva Gatineau, Stephanie Cluzet, Stephanie Krisa, Isabelle Papet, Carole Migne, Didier Remond, Dominique Dardevet, Sergio Polakof, Tristan Richard, Laurent Mosoni
Little is still known about brain protein synthesis. In order to increase our knowledge, we aimed to modulate brain protein synthesis rates through aging, variations in nutritional state (fed state...
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Potential of Borojoa patinoi Cuatrecasas water extract to inhibit nosocomial antibiotic resistant bacteria and cancer cell proliferation in vitro

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Food Funct., 2018, Advance Article
DOI: 10.1039/C7FO01542A, Paper
Clemencia Chaves-Lopez, Donatella Usai, Matthew Gavino Donadu, Annalisa Serio, Robert Tulio Gonzalez-Mina, Maria Chiara Simeoni, Paola Molicotti, Stefania Zanetti, Antonio Pinna, Antonello Paparella
Borojo is a fruit used in Colombian traditional medicine for its supposed healthy effects.
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Effect of diets with goat's milk fat associated with exercise on anxiety and oxidative stress in the brain of adult rats
Food Funct., 2018, Accepted Manuscript
DOI: 10.1039/C7FO01764B, Paper
MAYARA QUEIROGA BARBOSA, Rita Cassia Queiroga, Camila Carolina Meneses Santos Bertozzo, Marco Aurelio D. Bomfim, Gerlane Coelho Bernardo Guerra, Daline S. Fernandes Araujo, Jaielison Yandro Pereira da Silva, Louise IARA GOMES Gomes, Suedna Costa, Rui Bessa, Susana Alves, Juliana Kessia Barbosa Soares
The objective of this study was to evaluate the effects of goat milk fat associated with physical training on markers of oxidative stress in the brain and anxiety behavioral in...
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Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor
Food Funct., 2018, Accepted Manuscript
DOI: 10.1039/C8FO00107C, Paper
Xiaoguang Gao, Changyuan Wang, Chenqing Ning, Kexin Liu, Xinyuan Wang, Zhihao Liu, Huijun Sun, Xiaodong Ma, Pengyuan Sun, Qiang Meng
Hepatic fibrosis is a pathological process that eventually leads to development of cirrhosis and liver cancer by various types of chronic liver disease. Up to date, there is no standard...
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Influence of oil phase composition on antifungal and mycotoxin inhibitory activity of clove oil nanoemulsions
Food Funct., 2018, Accepted Manuscript
DOI: 10.1039/C7FO02073B, Paper
JING WAN, Shaobin Zhong, PAUL Schwarz, Bingcan Chen, Jiajia Rao
The influence of oil compositions on the physical properties, antifungal and mycotoxin inhibitory activity of clove oil-in-water nanoemulsion were investigated. The physically stable clove oil-in-water nanoemulsions could be fabricated by...
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Modifications in gut microbiota and fermentation metabolites in the hindgut of rats after the consumption of galactooligosaccharide glycated with fish peptide
Food Funct., 2018, Accepted Manuscript
DOI: 10.1039/C7FO02002C, Paper
Weiya Jin, Kaining Han, shiyuan dong, Yuhong Yang, Zhenjie Mao, Mingyue Su, Mingyong Zeng
The aim of this research was to investigate the impact of diet containing galactooligosaccharide (GOS)-fish peptide (FP) conjugates prepared via Maillard reaction on colonic fermentation properties and the composition of...
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Effect of bovine lactoferrin on L-DOPA absorption and metabolism in mice
Food Funct., 2018, Accepted Manuscript
DOI: 10.1039/C7FO01518F, Paper
Masayuki Ikeda, Hiroshi Iijima, Ichizo Shinoda, Hiroshi Iwamoto, Yasuhiro Takeda
Bioactive natural products, habitually ingested with milk, or its derivative nutrients have been studied for their bioavailability. In this study, we investigated the effects of the co-administration of bovine milk-derived...
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Anti-aging potential of tree nuts with a focus on the phytochemical composition, molecular mechanisms and thermal stability of major bioactive compounds

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Food Funct., 2018, Advance Article
DOI: 10.1039/C7FO01967J, Review Article
Marius Emil Rusu, Ana-Maria Gheldiu, Andrei Mocan, Laurian Vlase, Daniela-Saveta Popa
Tree nuts, complete functional foods, contain macro- and micronutrients of high biological value.
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