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Preview: Medscape Pathology & Laboratory Medicine Podcast

Medscape Pathology & Laboratory Medicine Podcast

Latest medical news and features from Medscape Pathology & Laboratory Medicine

Copyright: Copyright 2018, Medscape

Noninvasive Biomarkers of AD Will Soon Be Reality

Fri, 23 Mar 2018 12:39:28 EDT

Progress is being made in the search for a simple test for Alzheimer disease.

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A New Prostate Cancer Screening Trial--Anything to See Here?

Fri, 16 Mar 2018 10:06:43 EDT

Yet another trial on risks and benefits of widespread PSA screening. Dr Kenny Lin puts it in perspective.

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Overlooked Biomarker May Predict Cancer Immunotherapy Response

Thu, 15 Feb 2018 15:54:39 EST

Dr David Kerr on data showing that tumors with extensive aneuploidy may not benefit as much from immune checkpoint blockade.

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MABp1: 'Clever' New Antibody Targeting Colorectal Cancer

Wed, 14 Feb 2018 10:50:18 EST

A trial using MABp1, an antibody targeting interleukin 1 alpha, showed some benefit for patients with advanced colorectal cancer, but Dr Kerr thinks the clinical endpoint used was a 'little soft.'

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Next Steps for Immunotherapies, Cell Therapies in Oncology

Fri, 9 Feb 2018 09:38:44 EST

At ESMO 2017, Drs Zimmermann, Svane, and Coukos discuss successes and setbacks in immuno-oncology.

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'Cultural Change' in DCIS

Wed, 17 Jan 2018 17:15:12 EST

Some think it's time to change how we talk about DCIS and to consider de-escalation of therapy. Drs Kathy Miller and Shelley Hwang discuss these hot topics and the COMET study at SABCS 2017.

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Late Recurrence in ER- Positive Breast Cancer: Banking on Biomarkers

Wed, 17 Jan 2018 14:34:08 EST

Evaluation of biomarkers after 5 years of standard therapy for hormone-positive breast cancer may help determine those at risk for recurrence and those who may need further endocrine therapy.

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Wisely Choosing the Right Lab Tests

Mon, 11 Dec 2017 16:22:31 EST

Dr Lundberg discussed the American Society for Clinical Pathology's list of 20 lab tests you should carefully consider before ordering.

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Gestational Diabetes and Long-term Risk for CVD

Wed, 8 Nov 2017 10:03:30 EST

Dr JoAnn Manson comments on a recent study revealing that gestational diabetes is like a window into a woman's future risk for cardiovascular disease and type 2 diabetes.

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An Urgent Plea to Oncologists for HPV Vaccination

Thu, 2 Nov 2017 12:55:10 EDT

Oncologists fail to recommend HPV vaccination to young cancer survivors, even though it is a safe and effective cancer prevention strategy.

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With Sudden Death, Don't Automatically Blame the Heart

Mon, 9 Oct 2017 12:17:21 EDT

Drs Gayatri Acharya, Michael Ackerman, and Peter Noseworthy discuss the importance of investigating sudden deaths in light of new research showing that many presumed sudden cardiac deaths are not cardiac in origin.

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Leading Science Journalist Carl Zimmer on His Genome

Thu, 5 Oct 2017 09:37:21 EDT

Dr Eric Topol speaks with science journalist Carl Zimmer about where he gets his ideas, what his genome looks like, and how he got a tapeworm named after him.

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A Supplement That May Block The Toxic Effects of Alcohol

Tue, 26 Sep 2017 12:23:12 EDT

Dr Lundberg shares a possible aid for metabolizing alcohol.

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Life After the FDA: Mining Data and Reducing Disparities

Thu, 20 Jul 2017 16:53:26 EDT

Dr Califf talks about his new role at Verily and how data mining and data sharing could reduce disparities in care and improve patient outcomes.

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'Sparks Fly' and 'Momentous Discovery' in Brain Diseases Follows

Wed, 5 Jul 2017 11:33:19 EDT

Eric Topol gets the backstory from Beth Stevens on the amazing discoveries being made about the role of the immune system in neurologic diseases.

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Antineoplastic Agents in Breast Cancers With Mutational Signatures

Wed, 12 Apr 2017 14:50:50 EDT

Dr Markman encourages review of recently reported possible effect of ovarian cancer antineoplastic agents in breast cancer patients with rare BRCA mutational signatures.

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Biomarkers to Determine Who Gets Checkpoint Inhibitors

Mon, 3 Apr 2017 13:04:13 EDT

Reviewing recent research, Dr Jeffrey Weber concludes that an amalgam of host- and tumor-related markers will be the best indication of which patients should receive checkpoint inhibitors.

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The Most Transformational Biologist of Our Era?

Fri, 31 Mar 2017 12:00:28 EDT

Dr Eric Topol interviews CRISPR scientist Feng Zhang about his journey from China to the gene editing labs of America.

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Is Precision Oncology Really Precise?

Fri, 10 Mar 2017 11:30:50 EST

Without a gold standard for myriad parameters, precision oncology is imprecise, at best, argues Dr Lundberg.

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Are the Testosterone Trials the Final Word?

Mon, 6 Mar 2017 09:56:33 EST

The just-released Testosterone Trials provide more information on screening for or treating low T. Should family physicians intervene in older men?

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A Genetic Lead in ADHD

Mon, 27 Feb 2017 15:21:03 EST

Dr Alan Jacobs reports on the first functional evidence of gene variants with implications for the pathology of ADHD

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Sharing Genetic Data With Study Participants

Tue, 31 Jan 2017 14:56:02 EST

Dr Maurie Markman explains that sharing genetic data with study participants encourages greater clinical trial involvement.

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PSA Testing: A New, Simpler Way?

Mon, 7 Nov 2016 14:21:36 EST

Dr Chodak reviews a new algorithm intended to simplify PSA testing. But is it ready for prime time?

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Molecular Testing of Cancers: 'Let's Try to Get It Right'

Wed, 21 Sep 2016 13:27:51 EDT

Use of molecular diagnostics in cancer can be tricky, but Dr Lundberg says the pathologist can ask important questions to help guide the process.

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Citizen Science and Mapping the Microbiome

Tue, 21 Jun 2016 14:41:27 EDT

Jessica Richman, CEO of uBiome, talks about her passion for citizen science, her interest in the microbiome, and how uBiome aims to serve public health.

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Melanoma: ‘Tail’ on Survival Curve Is Getting Longer

Thu, 28 Apr 2016 11:22:51 EDT

Dr Jeffrey Weber, Medscape's new commentator on melanoma and immunotherapy, discusses impressive data on overall survival and combination therapy presented at AACR 2016.

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A Biotech Billionaire's Cancer 'Moonshot'

Wed, 20 Apr 2016 15:25:42 EDT

By leading an unprecedented group of companies, institutions, and scientists in Cancer Moonshot 2020, Patrick Soon-Shiong has set out to change cancer care forever. Here's how he plans to do it.

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Pharmacogenetic Testing for 5-FU Saves Lives and Money

Fri, 5 Feb 2016 14:50:11 EST

Prospective screening for a genetic variant of DPD, an enzyme that catabolizes 5-FU, reduces mortality from 10% to 0% in patients with this variant and is cost-effective. Dr David Kerr is all for it.

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Does Genetic Test 'Decipher' PCa Risk After Prostatectomy?

Tue, 26 Jan 2016 15:00:06 EST

The new Decipher genetic test may more accurately predict risk for metastasis following radical prostatectomy for prostate cancer, but will it improve outcomes?

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Declining PSA Screening Rates: Risky Business?

Wed, 13 Jan 2016 15:46:31 EST

Are declining PSA screening rates placing men at risk? Dr Chodak discusses the latest opinions for and against routine screening.

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Ovarian Cancer Screening: Resist the Temptation -- For Now

Tue, 12 Jan 2016 13:15:02 EST

New findings from the UK show multimodal ovarian cancer screening to be highly effective in reducing mortality, but Dr Andrew Kaunitz urges clinicians to await guidelines for routine screening.

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From Bedside to Bench: A New Direction in Breast Cancer Research

Tue, 12 Jan 2016 09:15:32 EST

Past AACR president Dr Carlos Arteaga describes translational studies and emerging therapies that are transforming the clinical practice of breast cancer.

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The Biggest Infectious Disease Threats

Thu, 10 Dec 2015 10:26:57 EST

Awareness about antimicrobial resistance got a boost through recent campaigns such as Get Smart About Antibiotics Week.

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Six Drugs for Resistant Pathogens: Good News From IDWeek

Mon, 2 Nov 2015 10:57:20 EST

Dr Paul Auwaerter shares good news from IDWeek 2015, including updates on anti-infectives--6 new weapons in the battle against resistant organisms.

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Leana Wen: Managing the Health of a City Amid the Freddie Gray Riots

Fri, 11 Sep 2015 17:18:32 EDT

Dr Leana Wen, city health commissioner for Baltimore, speaks with Medscape Editor-in-Chief Dr Eric Topol about her work as an emergency medicine physician and public health advocate.

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The Frightening Truth About Genetic Testing

Mon, 22 Jun 2015 12:55:47 EDT

Genetic testing is now ordered in the treatment of numerous cancer types. Is it useful? Is it even reliable? Dr John Marshall and world-class experts tackle key questions for practicing clinicians.

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20 Years Since BRCA2: Where Are We Now in Cancer Screening?

Mon, 13 Apr 2015 12:02:46 EDT

Eric Topol speaks with singer, songwriter, and oncologic scientist Nazneen Rahman on the importance of understanding the genetics of cancer.

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Mummies, Neanderthals, and Humans, Oh My!

Mon, 13 Apr 2015 12:01:12 EDT

Explorer of ancient DNA Svante Pääbo recounts to Eric Topol his journey from Egyptian mummies to sequencing the Neanderthal genome, and more.

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Can Molecular Profiling Lower Cancer Costs?

Wed, 24 Dec 2014 14:27:38 EST

Dr John Marshall asks tough questions of experts at the 2014 Ruesch Symposium about whether information gained from molecular testing can tailor therapy and lower costs.

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Immuno Death Ray to GI Cancers

Tue, 25 Nov 2014 09:59:53 EST

Can immunotherapy 'clip the force field' of gastrointestinal tumors? Dr John Marshall and experts say yes and will discuss advances during the Ruesch Symposium 2014, December 5, Washington, DC.

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Ebola: Your Lingering Questions Answered by Anthony Fauci

Mon, 27 Oct 2014 19:09:32 EDT

Dr Tony Fauci gives straightforward answers to lingering questions about Ebola in the United States.

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Vitamin D and Colon Cancer

Wed, 2 Jul 2014 12:13:12 EDT

David Kerr discusses a new 'umbrella review' of vitamin D studies from across the medical literature, and the potential implications for the prevention of colon cancer.

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Be on the Lookout for MERS-CoV

Mon, 23 Jun 2014 10:17:41 EDT

More cases of MERS-CoV in the United States are inevitable. Here's what you should look for, and what to do if you suspect MERS-CoV.

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Open-Access Science for Better Cancer Drugs

Mon, 14 Apr 2014 12:03:51 EDT

Dr. David Kerr says 90% of new cancer drugs 'fail.' To reverse this rate, he advocates a novel model for drug development in which science is shared in open-access, industry-academic partnerships.

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The Genetics of Living Longer, Healthier Lives

Tue, 1 Apr 2014 11:14:51 EDT

Dr. Nir Barzilai considers what research on the genetic makeup of very old healthy individuals might teach us about preventing age-related diseases.

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Is There Really a Sports Gene?

Fri, 21 Mar 2014 11:40:17 EDT

David Epstein, author of a book on sports genetics, considers what clinicians need to know about advances in sports and exercise genetics.

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BRCA and Risk for Ovarian Cancer: There's More to the Story

Mon, 17 Mar 2014 09:40:19 EDT

Dr. Maurie Markman considers whether strategies known to reduce the risk for ovarian cancer might also be useful in women with a BRCA mutation.

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Oophorectomy Prevents Ovarian Cancer

Fri, 14 Mar 2014 10:10:27 EDT

Dr. Maurie Markman suggests that the findings of this study be shared with women with the BRCA+ mutation.

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Berwick on CMS, Death Panels, and His Run for Governor

Tue, 18 Feb 2014 16:03:27 EST

Donald Berwick talks with Eric Topol about his decades-long career with the Institute for Healthcare Improvement, his tenure as Director of CMS, and why he's running for governor of Massachusetts.

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Best Colorectal Cancer Test: The One That Gets Done

Wed, 12 Feb 2014 10:38:16 EST

Providers must be more proactive if we are to raise national colorectal cancer screening rates.

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