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Muscular Dystrophy / ALS News From Medical News Today



Muscular dystrophy is a group of inherited diseases that are characterized by weakness and wasting away of muscle tissue, with or without the breakdown of nerve tissue. There are nine types of muscular dystrophy, with each type involving an eventual loss



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Gene silencing shows promise for treating two fatal neurological disorders

Fri, 14 Apr 2017 00:00:00 PDT

In two studies of mice, researchers showed that a drug, engineered to combat the gene that causes spinocerebellar ataxia type 2 (SCA2), might also be used to treat amyotrophic lateral sclerosis...



A new marker for the most common form of ALS

Fri, 31 Mar 2017 00:00:00 PDT

A molecule found in blood and cerebrospinal fluid could serve as an indicator for the most common form of amyotrophic lateral sclerosis (ALS), offering a much needed tool to measure disease...



Occupational exposure to magnetic fields increases risk of ALS

Thu, 30 Mar 2017 00:00:00 PDT

A new study finds that high exposure to extremely low-frequency magnetic fields through work significantly increases the risk of dying from ALS.



'Groundbreaking' technology enables quadriplegic man to move his limbs

Wed, 29 Mar 2017 00:00:00 PDT

Using neuroprosthetic technology, scientists have enabled a man who had been quadriplegic for 8 years to move his limbs and perform daily tasks.



Scientists discover shared genetic origin for ALS/MND and schizophrenia

Tue, 28 Mar 2017 00:00:00 PDT

Researchers have shown for the first time that Amyotrophic Lateral Sclerosis (ALS), also known as Motor Neurone Disease (MND) and schizophrenia have a shared genetic origin, indicating that the...



Researchers identify potential treatment for type of muscle and brain degenerative disease

Thu, 23 Mar 2017 00:00:00 PDT

UCLA researchers have discovered the molecular basis of, and identified potential treatment for, an incurable disease known as inclusion body myopathy, Paget disease with frontotemporal dementia...



New toxic pathway identified for protein aggregates in neurodegenerative disease

Mon, 20 Mar 2017 00:00:00 PDT

Led by professor Ludo Van Den Bosch (VIB-KU Leuven), scientists from Belgium, the UK and the US have identified new processes that form protein "clumps" that are characteristic of amyotrophic...



Caffeine may ward off dementia by boosting protective enzyme

Wed, 08 Mar 2017 09:00:00 PDT

Researchers have uncovered a number of compounds - including caffeine - that boost production of the enzyme NMNAT2, which may protect against dementia.



Red wine compound found to slow down neural aging in mice

Tue, 07 Mar 2017 08:00:00 PDT

New study shows that resveratrol reduces age-induced deterioration of neuromuscular synapses in mice. Anti-diabetes drug may also slow down muscular aging.



Molecular structure of the cell nucleoskeleton revealed for the first time

Thu, 02 Mar 2017 06:00:00 PDT

Using 3D electron microscopy, structural biologists from the University of Zurich succeeded in elucidating the architecture of the lamina of the cell nucleus at molecular resolution for the first...



Meditation benefits patients with ALS

Mon, 27 Feb 2017 00:00:00 PDT

An eight-week mindfulness-based meditation program led to improved quality of life and psychological well-being in clinical trial of patients with amyotrophic lateral sclerosis (ALS).



Children of patients with C9orf72 mutations are at a greater risk of frontotemporal dementia or ALS at a younger age

Wed, 15 Feb 2017 00:00:00 PDT

The most common genetic cause of the brain diseases frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) is a mutation in the C9orf72 gene.



Dietary supplement could improve heart health

Wed, 15 Feb 2017 00:00:00 PDT

Dietary intervention could benefit heart health in those with muscular dystrophy. That's according to new research published in Experimental Physiology.



Researchers show how Lou Gehrig's disease progression could be delayed

Mon, 13 Feb 2017 00:00:00 PDT

A team of biomedical scientists has identified a molecule that targets a gene known to play a critical role in the rapid progression of amyotrophic lateral sclerosis (ALS), sometimes known as Lou...



Gene discovery suggests new type of congenital muscular dystrophy

Fri, 10 Feb 2017 07:00:00 PDT

New study finds that mutations in INPP5K gene cause a new type of congenital muscular dystrophy with short stature, cataracts, and intellectual disability.



FDA approves drug to treat Duchenne muscular dystrophy

Fri, 10 Feb 2017 06:00:00 PDT

The U.S. Food and Drug Administration has approved Emflaza (deflazacort) tablets and oral suspension to treat patients age 5 years and older with Duchenne muscular dystrophy (DMD), a rare genetic...



Breakthrough technology enables communication in late-stage ALS

Wed, 01 Feb 2017 00:00:00 PDT

A brain-computer interface has been found to enable people in a completely locked-in state in the late stages of ALS to communicate meaningfully.



Rebalancing gut microbiome lengthens survival in mouse model of ALS

Tue, 31 Jan 2017 00:00:00 PDT

A bacterial by-product known to be important in maintaining gut health may slow the progression of amyotrophic lateral sclerosis, or ALS - a progressive, neurodegenerative disease.



Development of ALS syndromes caused by impairment of nuclear-cytoplasmic transport in motor neurons

Thu, 26 Jan 2017 00:00:00 PDT

A team of scientists led by Dr. Paulo A Ferreira at Duke University Medical Center and whose work was supported by the National Institutes of Health, has found evidence that derailing the transport...



Scientists stop and reverse Alzheimer's-related brain damage in mice

Thu, 26 Jan 2017 00:00:00 PDT

Scientists have found a molecule that restores normal levels of a protein responsible for Alzheimer's disease; tests were performed on mice and monkeys.



Study identifies potential drug targets for muscular dystrophy treatments

Wed, 11 Jan 2017 00:00:00 PDT

Myotonic dystrophy type I (MD1) is a common form of muscular dystrophy associated with muscle wasting, weakness, and myotonia.



TSRI scientists devise new approaches to personalized medicines

Tue, 13 Dec 2016 06:00:00 PDT

Scientists on the Florida campus of The Scripps Research Institute (TSRI) have developed broad methods to design precision medicines against currently incurable diseases caused by RNA.



12-month edaravone clinical study data in ALS presented at the 27th international symposium on als/mnd

Tue, 13 Dec 2016 02:00:00 PDT

Mitsubishi Tanabe Pharma Corporation (Head Office: Osaka; President & Representative Director, CEO: Dr.



Football players 'not at higher risk of neurodegenerative disease'

Mon, 12 Dec 2016 08:00:00 PDT

Given that football players have a high risk of head trauma, a new study investigates if this also puts them at risk of brain degenerative disease.



Study investigates how to turn stem cells into motor neurons

Fri, 09 Dec 2016 09:00:00 PDT

A team of researchers investigates details of the cellular mechanisms involved in transforming a stem cell into a motor neuron, through direct programming.