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Huntington's Disease News From Medical News Today

Huntington's disease is a genetic disorder that damages certain nerve cells in the brain. The damage to the cells in the brain becomes progressively worse until areas of the brain no longer function properly. Movement, cognition, and behavior are affected

Copyright: Copyright 2017 Medical News Today

Study uncovers a mechanism driving cognitive symptoms in Huntington's disease

Wed, 08 Mar 2017 00:00:00 PDT

Individuals affected by Huntington's disease (HD) inherit a mutation in the Huntingtin gene (HTT) that causes the encoded HTT protein to misfold and accumulate in neurons.

New discovery is a step towards developing Huntington's disease treatments before symptoms appear

Fri, 24 Feb 2017 00:00:00 PDT

Early warning signs of Huntington's disease have been uncovered in a sheep carrying the human HD mutation, leading the way for new insight into this devastating illness, a new study in Scientific...

Hope for new treatment for Huntington's disease

Tue, 21 Feb 2017 00:00:00 PDT

Researchers working at Karolinska Institutet in Sweden and University of Southern Denmark have managed to produce short synthetic DNA analogues - oligonucleotides - that bind direct to the gene...

'Helper cells' can turn toxic in brain injury and diseases

Mon, 06 Feb 2017 07:00:00 PDT

Astrocytes induced by central nervous system injury and disease normally help repair damage. Now, a study finds some can turn rogue and kill cells instead.

Huntington's disease linked to dysfunction of brain structure

Fri, 23 Dec 2016 00:00:00 PDT

Study helps explain why gene mutation causes debilitating symptoms and loss of brain tissue.

Tufts researchers uncover possible source of genetic error causing multiple diseases

Tue, 06 Dec 2016 06:00:00 PDT

Tufts University researchers have discovered a possible explanation for the occurrence of a genetic error that causes over a dozen neuromuscular and neurodegenerative disorders, including...

Huntington's disease affects muscle as well as brain

Wed, 30 Nov 2016 07:00:00 PDT

After studying cell processes in mice, researchers suggest Huntington’s disease involves defects in muscle maturation as well as death of brain cells.

Scripps Florida scientists pinpoint regulator of amphetamine induced motor activity

Mon, 21 Nov 2016 09:00:00 PDT

In new findings that could have an impact on the development of therapies for a number of currently untreatable brain disorders such as Parkinson's and Huntington's diseases, scientists from the...

The messenger in Huntington's disease

Fri, 11 Nov 2016 00:00:00 PDT

A research effort at the Centre for Genomic Regulation in Barcelona, Spain, reveals new molecular mechanisms of Huntington's disease.

Stanford study identifies new biomarkers for Huntington's disease

Wed, 09 Nov 2016 00:00:00 PDT

Researchers at Stanford University School of Medicine have identified several new biological markers to measure the progression of the inherited neurodegenerative disorder Huntington's disease (HD).

Activity of Huntington's disease gene curbed for 6 months in mice

Mon, 12 Sep 2016 00:00:00 PDT

A single injection of a new treatment has reduced the activity of the gene responsible for Huntington's disease for several months in a trial in mice.

Researchers identify how a single gene can protect against causes of neurodegenerative diseases

Tue, 02 Aug 2016 09:00:00 PDT

New research has identified how cells protect themselves against 'protein clumps' known to be the cause of neurodegenerative diseases including Alzheimer's, Parkinson's and Huntington's disease.

Novel compound has promise for treatment of Huntington's disease

Mon, 18 Jul 2016 00:00:00 PDT

A major, multi-institutional study based at Massachusetts General Hospital (MGH) has identified a promising treatment strategy for Huntington's disease (HD).

Drug helps control involuntary, sudden movements of Huntington disease

Wed, 06 Jul 2016 00:00:00 PDT

In a study appearing in JAMA, Samuel Frank, M.D., of Harvard Medical School, Boston, and the Huntington Study Group, and colleagues evaluated the efficacy and safety of the drug deutetrabenazine to...

Huntington's risk genes '10 times more common than previously thought'

Thu, 23 Jun 2016 00:00:00 PDT

A study of more than 7,300 adults suggests the number of people at low risk of Huntington's disease is 10 times higher than previous estimates report.

New brain map could enable novel therapies for autism and Huntington's disease

Tue, 21 Jun 2016 09:00:00 PDT

USC scientists have mapped an uncharted portion of the mouse brain to explain which circuit disruptions might occur in disorders such as Huntington's disease and autism.

Swapping sick for healthy brain cells slows Huntington's disease

Wed, 08 Jun 2016 05:00:00 PDT

Researchers have successfully reduced the symptoms and slowed the progression of Huntington's disease in mice using healthy human brain cells.

Scripps Florida scientists create compound that erases disease-causing RNA defects

Thu, 02 Jun 2016 00:00:00 PDT

In an important new study with implications for the treatment of dozens of incurable diseases, scientists from the Florida campus of The Scripps Research Institute (TSRI) have for the first time...

Neurodegenerative disease damage reversed in fruit flies

Sun, 01 May 2016 00:00:00 PDT

Scientists have reversed damage to nerve cells by inhibiting two metabolites that are linked to nerve cell death, raising hopes for a future treatment.

A new player revealed in nerve growth process

Thu, 21 Apr 2016 01:00:00 PDT

Role of adaptor protein CD2AP in neuron sprouting discovered by UofL researchers could lead to therapies for Alzheimer's disease, stroke recovery and spinal cord injury.

UCI team finds method to reduce accumulation of damaging Huntington's disease protein

Mon, 18 Apr 2016 03:00:00 PDT

A study appearing April 14 in the journal Neuron suggests there may be a new way to change the damaging course of Huntington disease.

A common brain cell shapes the nervous system in unexpected ways

Tue, 12 Apr 2016 03:00:00 PDT

More than half of our brains are made up of glial cells, which wrap around nerve fibers and insulate them--similarly to how the plastic casing of an electric cable insulates the copper wire...

A newly discovered way for cells to die

Mon, 11 Apr 2016 00:00:00 PDT

Some cells are meant to live, and some are meant to die. The linker cell of Caenorhabditis elegans, a tiny worm that is a favored model organism for biologists, is among those destined for...

Huntington's disease gene dispensable in adult mice

Tue, 08 Mar 2016 05:00:00 PDT

Adult mice don't need the gene that, when mutated in humans, causes the inherited neurodegenerative disorder Huntington's disease.

Songbirds pinpoint effects of Huntington's disease

Tue, 08 Mar 2016 01:00:00 PDT

Action of gene traced in brain area for complex movements. Although Huntington's disease is caused by mutations in a single gene, understanding how it ravages the brain and body has been...