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Huntington's Disease News From Medical News Today

Huntington's disease is a genetic disorder that damages certain nerve cells in the brain. The damage to the cells in the brain becomes progressively worse until areas of the brain no longer function properly. Movement, cognition, and behavior are affected

Copyright: Copyright 2016 Medical News Today

Activity of Huntington's disease gene curbed for 6 months in mice

Mon, 12 Sep 2016 00:00:00 PDT

A single injection of a new treatment has reduced the activity of the gene responsible for Huntington's disease for several months in a trial in mice.

Researchers identify how a single gene can protect against causes of neurodegenerative diseases

Tue, 02 Aug 2016 09:00:00 PDT

New research has identified how cells protect themselves against 'protein clumps' known to be the cause of neurodegenerative diseases including Alzheimer's, Parkinson's and Huntington's disease.

Novel compound has promise for treatment of Huntington's disease

Mon, 18 Jul 2016 00:00:00 PDT

A major, multi-institutional study based at Massachusetts General Hospital (MGH) has identified a promising treatment strategy for Huntington's disease (HD).

Drug helps control involuntary, sudden movements of Huntington disease

Wed, 06 Jul 2016 00:00:00 PDT

In a study appearing in JAMA, Samuel Frank, M.D., of Harvard Medical School, Boston, and the Huntington Study Group, and colleagues evaluated the efficacy and safety of the drug deutetrabenazine to...

Huntington's risk genes '10 times more common than previously thought'

Thu, 23 Jun 2016 00:00:00 PDT

A study of more than 7,300 adults suggests the number of people at low risk of Huntington's disease is 10 times higher than previous estimates report.

New brain map could enable novel therapies for autism and Huntington's disease

Tue, 21 Jun 2016 09:00:00 PDT

USC scientists have mapped an uncharted portion of the mouse brain to explain which circuit disruptions might occur in disorders such as Huntington's disease and autism.

Swapping sick for healthy brain cells slows Huntington's disease

Wed, 08 Jun 2016 05:00:00 PDT

Researchers have successfully reduced the symptoms and slowed the progression of Huntington's disease in mice using healthy human brain cells.

Scripps Florida scientists create compound that erases disease-causing RNA defects

Thu, 02 Jun 2016 00:00:00 PDT

In an important new study with implications for the treatment of dozens of incurable diseases, scientists from the Florida campus of The Scripps Research Institute (TSRI) have for the first time...

Neurodegenerative disease damage reversed in fruit flies

Sun, 01 May 2016 00:00:00 PDT

Scientists have reversed damage to nerve cells by inhibiting two metabolites that are linked to nerve cell death, raising hopes for a future treatment.

A new player revealed in nerve growth process

Thu, 21 Apr 2016 01:00:00 PDT

Role of adaptor protein CD2AP in neuron sprouting discovered by UofL researchers could lead to therapies for Alzheimer's disease, stroke recovery and spinal cord injury.

UCI team finds method to reduce accumulation of damaging Huntington's disease protein

Mon, 18 Apr 2016 03:00:00 PDT

A study appearing April 14 in the journal Neuron suggests there may be a new way to change the damaging course of Huntington disease.

A common brain cell shapes the nervous system in unexpected ways

Tue, 12 Apr 2016 03:00:00 PDT

More than half of our brains are made up of glial cells, which wrap around nerve fibers and insulate them--similarly to how the plastic casing of an electric cable insulates the copper wire...

A newly discovered way for cells to die

Mon, 11 Apr 2016 00:00:00 PDT

Some cells are meant to live, and some are meant to die. The linker cell of Caenorhabditis elegans, a tiny worm that is a favored model organism for biologists, is among those destined for...

Huntington's disease gene dispensable in adult mice

Tue, 08 Mar 2016 05:00:00 PDT

Adult mice don't need the gene that, when mutated in humans, causes the inherited neurodegenerative disorder Huntington's disease.

Songbirds pinpoint effects of Huntington's disease

Tue, 08 Mar 2016 01:00:00 PDT

Action of gene traced in brain area for complex movements. Although Huntington's disease is caused by mutations in a single gene, understanding how it ravages the brain and body has been...

Antisense drug for Huntington's looks promising

Sat, 27 Feb 2016 00:00:00 PDT

A treatment that may block and reverse the effects of Huntington's disease has been safely tested in mice and monkeys, and there are plans to carry out human trials.

UT Southwestern scientists find potential treatment for Friedreich's ataxia

Wed, 17 Feb 2016 04:00:00 PDT

Researchers at UT Southwestern Medical Center have identified synthetic RNA and DNA that reverses the protein deficiency causing Friedreich's ataxia, a neurological disease for which there is...

Structure of brain plaques in Huntington's disease described by Pitt team

Thu, 04 Feb 2016 03:00:00 PDT

Researchers at the University of Pittsburgh School of Medicine have shown that the core of the protein clumps found in the brains of people with Huntington's disease have a distinctive structure, a...

Delivering genes across the blood-brain barrier

Tue, 02 Feb 2016 04:00:00 PDT

Caltech biologists have developed a vector capable of noninvasive delivery of genetic cargo throughout the adult central nervous system.

Formulation scientists to rescue patients with pulmonary arterial hypertension

Fri, 15 Jan 2016 06:00:00 PDT

Overview of a type of high blood pressure of the arteries of the lungs and the heart and a new patient-friendly inhalation treatment.

Existing compound holds promise for reducing Huntington's disease progression

Tue, 08 Dec 2015 00:00:00 PDT

Currently, there is no treatment to halt the progression of Huntington's disease (HD), a fatal genetic disorder that slowly robs sufferers of their physical and mental abilities.

New research sheds light on neuronal communication

Thu, 03 Dec 2015 04:00:00 PDT

Synaptic proteins and neuronal transmission. A synapse consists of a presynaptic terminal of one neuron and a postsynaptic terminal of another.

Protecting the brain from Parkinson's disease

Thu, 03 Dec 2015 00:00:00 PDT

Researchers help the brain make GM1 ganglioside, a protective substance that is diminished in the brains of Parkinson's patients.

Yet another role for aspirin?

Mon, 30 Nov 2015 07:00:00 PDT

Salicylic acid and derivatives could help prevent neurodegenerative diseases such as Alzheimer's by binding to GAPDH and preventing it from entering nuclei, causing cell death.

UF Health researchers identify novel proteins linked to Huntington's disease

Thu, 19 Nov 2015 09:00:00 PDT

University of Florida Health researchers have made a new discovery about Huntington's disease, showing that the gene that causes the fatal disorder makes an unexpected "cocktail" of mutant proteins...