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Preview: Clinical Trials / Drug Trials News From Medical News Today

Clinical Trials / Drug Trials News From Medical News Today

Clinical trials are a type of research study to explore whether a medical treatment, drug, strategy or device is safe and effective for human use. The purpose of clinical trials is research, so the studies follow strict scientific standards. These standar

Copyright: Copyright 2017 Medical News Today

Better health for women involved in clinical trials

Tue, 14 Feb 2017 06:00:00 PST

Women who participate in obstetric and gynaecology clinical trials experience improved health outcomes compared to those who are not involved in trials, according to research by Queen Mary...

New clinical guideline issued for treating low back pain

Tue, 14 Feb 2017 00:00:00 PST

The American College of Physicians have just issued their clinical practice guideline for the noninvasive treatment of nonradicular low back pain.

Aspirin increases pregnancy rate in women with inflammation

Mon, 13 Feb 2017 00:00:00 PST

A new study examines the effect of a low dose of daily aspirin in women who are trying to conceive and have chronic, low-grade inflammation.

Epilepsy drug discovered in fish model shows promise in small pediatric clinical trial

Mon, 13 Feb 2017 00:00:00 PST

"Bench-to-bedside" describes research that has progressed from basic science in animal models that has led to therapies used in patients.

Alpha-lipoic acid prevents kidney stones in mouse model of rare genetic disease

Wed, 08 Feb 2017 00:00:00 PST

Alpha-lipoic acid, a dietary supplement widely available to consumers, prevented stone formation in a mouse model of cystinuria, a rare inherited disease that causes recurrent formation of painful...

Multiple sclerosis: 'Resetting' immune system may achieve long-term remission

Fri, 03 Feb 2017 08:00:00 PST

A small clinical trial reveals that over two thirds of patients with multiple sclerosis have been in remission for 5 years after stem cell transplantation.

Two new trials for pediatric brain cancer open at UTHealth/Children's Memorial Hermann

Wed, 01 Feb 2017 06:00:00 PST

Two new clinical trials for pediatric brain cancer have begun at The University of Texas Health Science Center at Houston (UTHealth) and Children's Memorial Hermann Hospital.

Why the bar needs to be raised for human clinical trials

Mon, 30 Jan 2017 06:00:00 PST

Standards for authorizing first-time trials of drugs in humans are lax, and should be strengthened in several ways, McGill University researchers argue in a paper published in Nature.

Scientists stop and reverse Alzheimer's-related brain damage in mice

Thu, 26 Jan 2017 00:00:00 PST

Scientists have found a molecule that restores normal levels of a protein responsible for Alzheimer's disease; tests were performed on mice and monkeys.

Study establishes new standard of care for pancreatic cancer patients

Wed, 25 Jan 2017 00:00:00 PST

A combination of two chemotherapy drugs - gemcitabine and capecitabine - should be the new standard of care for pancreatic cancer patients who have had surgery to remove their tumour, according to...

New clinical trial shows 'promising results' for ASD treatment

Mon, 23 Jan 2017 08:00:00 PST

Researchers from Arizona State University are developing autism treatments by improving the gut microbiota through fecal microbial transplants.

Financial ties between researchers and drug industry linked to positive trial results

Fri, 20 Jan 2017 06:00:00 PST

Financial ties between researchers and companies that make the drugs they are studying are independently associated with positive trial results, suggesting bias in the evidence base, concludes a...

Successful antibody trial in HIV-infected individuals

Thu, 19 Jan 2017 00:00:00 PST

A research team led by investigators of the Rockefeller University in New York and Prof Florian Klein, University Hospital Cologne and German Center for Infection Research (DZIF), has tested a new...

Acupuncture may relieve excessive crying in infants

Tue, 17 Jan 2017 00:00:00 PST

A new, randomized controlled trial suggests that acupuncture may help to alleviate babies' excessive crying, also known as infantile colic.

Pragmatic approach to using animal tissue

Fri, 13 Jan 2017 06:00:00 PST

Using animals to research potentially life-saving treatments for humans is a necessary part of the scientific process, though progress has been made in reducing the number of animals involved.

Malaria elimination: Vaccines should be tested on larger groups of volunteers

Fri, 13 Jan 2017 06:00:00 PST

To find an effective vaccine against malaria it is crucial to test candidate vaccines on larger groups of people than previously thought - according to a new study published in PLOS Computational...

Halozyme announces Phase 2 study in advanced pancreas cancer meets key endpoints

Tue, 10 Jan 2017 06:00:00 PST

Halozyme Therapeutics, Inc. has reported topline results from the combined analysis of Stages 1 and 2 and Stage 2 alone of its HALO 202 study, a Phase 2 randomized, multi-center clinical trial of...

Malaria: Next-generation vaccine shows efficacy, safety in humans

Sun, 08 Jan 2017 00:00:00 PST

A novel vaccine that uses a weakened form of a malaria parasite has produced an effective immune response in humans, without any adverse side effects.

Review examines diversity in dermatology clinical trials

Fri, 06 Jan 2017 00:00:00 PST

Racial and ethnic groups can be underrepresented in medical research. So what is the makeup of participants in randomized clinical trials of common dermatologic conditions?

Ogeda announces positive data from Phase IIa trial of fezolinetant (ESN364) in the treatment of menopausal hot flashes

Thu, 05 Jan 2017 06:00:00 PST

Ogeda, a clinical-stage drug discovery company that invents and develops small molecule drug candidates targeting G-protein coupled receptors (GPCRs), has announced positive top line data from the...

Benefits of morning sickness drug questioned by 40-year-old study

Thu, 05 Jan 2017 02:00:00 PST

New information on a previously unpublished 40-year-old study raises questions about the benefits of the morning sickness drug pyridoxine-doxylamine.

Early-phase trial demonstrates shrinkage in pediatric neural tumors

Wed, 04 Jan 2017 00:00:00 PST

In an early-phase clinical trial of a new oral drug, selumetinib, children with the common genetic disorder neurofibromatosis type 1 (NF1) and plexiform neurofibromas, tumors of the peripheral...

Publication of ocrelizumab trials: Hope for progressive MS

Fri, 23 Dec 2016 06:00:00 PST

Ocrelizumab can slow progression of MS. This is according to the newly published results of its phase 3 trials.

Light therapy 'a huge leap forward' for early prostate cancer treatment

Tue, 20 Dec 2016 08:00:00 PST

In a new study, a novel light therapy called VTP led to complete remission in almost half of men with early localized prostate cancer.

A year in review: The most popular medical research of 2016

Wed, 14 Dec 2016 08:00:00 PST

This year has seen an incredible range of innovation and advances. Here, we cover some of the most talked-about research from Medical News Today in 2016.