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Preview: Clinical Trials / Drug Trials News From Medical News Today

Clinical Trials / Drug Trials News From Medical News Today



Clinical trials are a type of research study to explore whether a medical treatment, drug, strategy or device is safe and effective for human use. The purpose of clinical trials is research, so the studies follow strict scientific standards. These standar



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Financial ties between researchers and drug industry linked to positive trial results

Fri, 20 Jan 2017 06:00:00 PST

Financial ties between researchers and companies that make the drugs they are studying are independently associated with positive trial results, suggesting bias in the evidence base, concludes a...



Successful antibody trial in HIV-infected individuals

Thu, 19 Jan 2017 00:00:00 PST

A research team led by investigators of the Rockefeller University in New York and Prof Florian Klein, University Hospital Cologne and German Center for Infection Research (DZIF), has tested a new...



Acupuncture may relieve excessive crying in infants

Tue, 17 Jan 2017 00:00:00 PST

A new, randomized controlled trial suggests that acupuncture may help to alleviate babies' excessive crying, also known as infantile colic.



Pragmatic approach to using animal tissue

Fri, 13 Jan 2017 06:00:00 PST

Using animals to research potentially life-saving treatments for humans is a necessary part of the scientific process, though progress has been made in reducing the number of animals involved.



Malaria elimination: Vaccines should be tested on larger groups of volunteers

Fri, 13 Jan 2017 06:00:00 PST

To find an effective vaccine against malaria it is crucial to test candidate vaccines on larger groups of people than previously thought - according to a new study published in PLOS Computational...



Halozyme announces Phase 2 study in advanced pancreas cancer meets key endpoints

Tue, 10 Jan 2017 06:00:00 PST

Halozyme Therapeutics, Inc. has reported topline results from the combined analysis of Stages 1 and 2 and Stage 2 alone of its HALO 202 study, a Phase 2 randomized, multi-center clinical trial of...



Malaria: Next-generation vaccine shows efficacy, safety in humans

Sun, 08 Jan 2017 00:00:00 PST

A novel vaccine that uses a weakened form of a malaria parasite has produced an effective immune response in humans, without any adverse side effects.



Review examines diversity in dermatology clinical trials

Fri, 06 Jan 2017 00:00:00 PST

Racial and ethnic groups can be underrepresented in medical research. So what is the makeup of participants in randomized clinical trials of common dermatologic conditions?



Ogeda announces positive data from Phase IIa trial of fezolinetant (ESN364) in the treatment of menopausal hot flashes

Thu, 05 Jan 2017 06:00:00 PST

Ogeda, a clinical-stage drug discovery company that invents and develops small molecule drug candidates targeting G-protein coupled receptors (GPCRs), has announced positive top line data from the...



Benefits of morning sickness drug questioned by 40-year-old study

Thu, 05 Jan 2017 02:00:00 PST

New information on a previously unpublished 40-year-old study raises questions about the benefits of the morning sickness drug pyridoxine-doxylamine.



Early-phase trial demonstrates shrinkage in pediatric neural tumors

Wed, 04 Jan 2017 00:00:00 PST

In an early-phase clinical trial of a new oral drug, selumetinib, children with the common genetic disorder neurofibromatosis type 1 (NF1) and plexiform neurofibromas, tumors of the peripheral...



Publication of ocrelizumab trials: Hope for progressive MS

Fri, 23 Dec 2016 06:00:00 PST

Ocrelizumab can slow progression of MS. This is according to the newly published results of its phase 3 trials.



Light therapy 'a huge leap forward' for early prostate cancer treatment

Tue, 20 Dec 2016 08:00:00 PST

In a new study, a novel light therapy called VTP led to complete remission in almost half of men with early localized prostate cancer.



A year in review: The most popular medical research of 2016

Wed, 14 Dec 2016 08:00:00 PST

This year has seen an incredible range of innovation and advances. Here, we cover some of the most talked-about research from Medical News Today in 2016.



Additions to standard multiple myeloma therapy do not appear to yield additional benefit

Thu, 08 Dec 2016 00:00:00 PST

Largest randomized trial finds second round of chemotherapy or stem cell transplant does not improve progression-free survival.



New data shed light on potential advantages of pacritinib for patients with myelofibrosis

Thu, 08 Dec 2016 00:00:00 PST

Pacritinib, currently on hold by the FDA, appears to be more effective in reducing spleen volume; twice-daily dose improves symptoms - this analysis comes from data before the clinical hold.



Cancer drug ibrutinib found helpful in treating graft versus host disease after transplant

Thu, 08 Dec 2016 00:00:00 PST

Ibrutinib could be promising new option for patients who don't respond to corticosteroid treatment.



Experimental drug for spinal muscular atrophy shows promising early results, prompting phase 3 clinical trial

Wed, 07 Dec 2016 06:00:00 PST

A new drug for spinal muscular atrophy has shown promising early results in a phase 2 trial involving 20 babies with infantile-onset spinal muscular atrophy.



Combination immune therapy shows promise against Hodgkin lymphoma

Tue, 06 Dec 2016 06:00:00 PST

The combination of two new drugs that harness the body's immune system is safe and effective, destroying most cancer cells in 64 percent of patients with recurrent Hodgkin lymphoma, according to...



Nivolumab with chemotherapy improves response, survival in AML study patients

Tue, 06 Dec 2016 06:00:00 PST

The immunotherapy drug nivolumab in combination with standard chemotherapy more than doubled response rates and improved overall survival in patients with acute myeloid leukemia (AML), according to...



Phase I trial shows that a drug that inhibits the Notch signalling process is active in a range of advanced cancers

Mon, 05 Dec 2016 00:00:00 PST

A new anti-cancer drug that inhibits a key cell signalling process involved in many different cancers has shown that it is capable of stopping the progression of cancer and shrinking tumours.



Advanced soft tissue sarcomas respond to a combination of a new and an existing anti-cancer drug

Mon, 05 Dec 2016 00:00:00 PST

Researchers working to find effective treatments for soft tissue sarcomas have discovered that combining a new anti-cancer drug with an existing one kills cancer cells not only in the laboratory...



Alzheimer's: Are we on the right path to new drugs?

Wed, 30 Nov 2016 08:00:00 PST

Following the news that Alzheimer's drug solanezumab has failed clinical trials, we look at whether researchers are on the right track for new treatments



Eli Lilly Alzheimer's drug fails to show benefits in final stage clinical trial

Thu, 24 Nov 2016 06:00:00 PST

Eli Lilly and Company has announced that their drug solanezumab has failed to meet its primary endpoint of slowing cognitive decline in people with mild Alzheimer's disease.



Rheumatoid arthritis drugs - direct switch has a beneficial effect

Wed, 16 Nov 2016 06:00:00 PST

For the first time, a multicentre study headed up by MedUni Vienna has compared the action of two rheumatoid arthritis drugs from the same class.