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Preview: Clinical Trials / Drug Trials News From Medical News Today

Clinical Trials / Drug Trials News From Medical News Today



Clinical trials are a type of research study to explore whether a medical treatment, drug, strategy or device is safe and effective for human use. The purpose of clinical trials is research, so the studies follow strict scientific standards. These standar



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Phase 3 trial confirms superiority of tocilizumab to steroids for giant cell arteritis

Fri, 28 Jul 2017 00:00:00 PDT

A phase 3 clinical trial has confirmed that regular treatment with tocilizumab, an inhibitor of interleukin-6, successfully reduced both symptoms of and the need for high-dose steroid treatment for...



Experimental HIV vaccine regimen is well-tolerated, elicits immune responses

Wed, 26 Jul 2017 00:00:00 PDT

Results from an early-stage clinical trial called APPROACH show that an investigational HIV vaccine regimen was well-tolerated and generated immune responses against HIV in healthy adults.



HIV: Could new injection work as effectively as daily drugs?

Tue, 25 Jul 2017 02:00:00 PDT

A new, long-acting antiretroviral injection is as effective in managing HIV as daily-dosage oral drugs, a recent clinical trial suggests.



Clinical trial shows some promise for Duchenne muscular dystrophy drug

Thu, 20 Jul 2017 00:00:00 PDT

The results of an international clinical trial, led in part by a UC Davis School of Medicine expert, have shown that a drug therapy for a severe type of muscular dystrophy holds promise for a...



Exclusion of mothers-to-be from clinical studies unfair and potentially harmful

Wed, 19 Jul 2017 00:00:00 PDT

The widely accepted principle that mums-to-be are a 'vulnerable' group unfairly excludes them from taking part in clinical studies, and perpetuates the knowledge void around the impact of drugs taken...



CAR T-cell therapy for leukemia leads to remissions in clinical trial

Wed, 19 Jul 2017 00:00:00 PDT

Researchers at Fred Hutchinson Cancer Research Center showed about 70 percent of patients with the most common adult leukemia had their tumors shrink or disappear following an experimental chimeric...



Clinical trial looks at tramadol for opioid withdrawal

Thu, 13 Jul 2017 00:00:00 PDT

A randomized clinical trial published by JAMA Psychiatry compared tramadol extended-release with clonidine and buprenorphine for the management of opioid withdrawal symptoms in patients with opioid...



Autism: Which children respond to oxytocin treatment?

Wed, 12 Jul 2017 00:00:00 PDT

Oxytocin treatment is thought to improve sociability in some children. A new clinical trial investigates which children are likely to respond best and why.



Viagra may reduce blood clots after stent surgery

Tue, 11 Jul 2017 00:00:00 PDT

New research suggests stents coated with sildenafil may have a much lower chance of causing blood clotting or artery narrowing than other stents.



Computer game may improve symptoms of mild cognitive impairment

Mon, 03 Jul 2017 00:00:00 PDT

Researchers from the University of Cambridge have developed a brain training app that boosts memory in people with mild cognitive impairment.



Cancer researchers overestimate reproducibility of preclinical studies

Thu, 29 Jun 2017 11:00:00 PDT

Cancer scientists overestimate the extent to which high-profile preclinical studies can be successfully replicated, new research published in the open access journal PLOS Biology by Jonathan...



Study reveals how sex 'blindspot' could misdirect medical research

Thu, 29 Jun 2017 00:00:00 PDT

The sex of animals frequently has an effect in biomedical research and therefore should be considered in the study of science, report an international team of scientists from the Wellcome Trust...



Yoga just as good as physical therapy for low back pain

Tue, 20 Jun 2017 00:00:00 PDT

A new trial establishes that yoga is "statistically as effective" as physical therapy for treating chronic low back pain.



Plant compound 'much more effective' than traditional anti-HIV drug

Fri, 16 Jun 2017 09:00:00 PDT

New research finds a plant extract that is much more effective at inhibiting HIV's ability to infect healthy cells than the traditional AZT.



Study questions whether mistaken antibodies led cancer research down a 20-year dead end

Fri, 16 Jun 2017 00:00:00 PDT

For nearly two decades researchers have sought a way to target an estrogen receptor in the hope they could improve breast cancer survival, but an article published in Nature Communications contends...



Clinical trial shows traditional treatment is better for iron-deficiency anemia

Thu, 15 Jun 2017 00:00:00 PDT

Although current treatments for iron-deficiency anemia can be effective, they commonly fail because pediatric patients do not complete the treatment and might experience adverse effects related to...



Previously unpublished trial data explain effects and side effects of key MS drug

Tue, 13 Jun 2017 00:00:00 PDT

Alemtuzumab is a highly effective drug for multiple sclerosis, approved in more than 60 countries and used by more than 12,000 patients worldwide.



Arthritis drug could cure severe heart condition

Tue, 13 Jun 2017 00:00:00 PDT

Researchers find that drug being tested for the treatment of rheumatoid arthritis may also hold the key to preventing aortic valve stenosis.



Promising new treatment option for chronic plaque psoriasis

Thu, 08 Jun 2017 00:00:00 PDT

Affecting more than 6 million Americans, chronic plaque psoriasis manifests as patches of red, scaly skin most frequently on the scalp, elbows and knees.



New chemotherapy approach offers breast cancer patients a better quality of life

Wed, 07 Jun 2017 00:00:00 PDT

The chemotherapy drug capecitabine gives patients a better quality of life and is as effective at preventing breast cancer from returning as the alternative regimen called CMF, when given following...



Common acne medication offers new treatment for multiple sclerosis

Tue, 06 Jun 2017 06:00:00 PDT

Study results offer safe and affordable treatment option.A Canadian clinical trial led by researchers at the University of Calgary's Hotchkiss Brain Institute (HBI), at the Cumming School of...



Ovarian cancer drug delivers 'very promising' results in early trial

Tue, 06 Jun 2017 06:00:00 PDT

Drug that mimics action of folic acid shrinks half of tumours.A new targeted treatment for ovarian cancer has shown 'very promising' results in an early clinical trial - shrinking tumours in...



Immunotherapy drug effective for metastatic triple negative breast cancer

Tue, 06 Jun 2017 00:00:00 PDT

Pembrolizumab shown to shrink tumors - regardless of whether patient had prior treatment.



Adding abiraterone to standard treatment improves prostate cancer survival by 40 per cent

Mon, 05 Jun 2017 06:00:00 PDT

Adding abiraterone to hormone therapy at the start of treatment for prostate cancer improves survival by 37 per cent, according to the results of one of the largest ever clinical trials for prostate...



Ketamine may not reduce post-surgery pain, delirium

Wed, 31 May 2017 00:00:00 PDT

A new clinical trial suggests that the drug currently used to reduce postoperative pain and delirium may not be effective after all.