Cancer / Oncology News From Medical News Today

Chemotherapy During Pregnancy Does Not Risk The Child's General Health

Fri, 10 Feb 2012 14:00:00 PST

A recent study published by the The Lancet Oncology indicates that children of women who received chemotherapy during their pregnancy suffer no adverse effects, developing as well as children in the general population. The study was led by Dr Frédéric Amant, Multidisciplinary Breast Cancer Center, Leuven Cancer Institute, Katholieke Universiteit Leuven, Belgium...

Cancer Drug Reverses Symptoms Of Alzheimer's In Mice

Fri, 10 Feb 2012 03:00:00 PST

A drug approved for the treatment of cancer appears to quickly reverse the symptoms of Alzheimer's in mice, according to a new study from the US published in the journal Science on Thursday. The Food and Drug Administration (FDA) approved bexarotene as a treatment for cutaneous T cell lymphoma, a type of skin cancer, in 2000...

How DNA Finds Its Match

Fri, 10 Feb 2012 01:00:00 PST

It's been more than 50 years since James Watson and Francis Crick showed that DNA is a double helix of two strands that complement each other. But how does a short piece of DNA find its match, out of the millions of 'letters' in even a small genome? New work by researchers at the University of California, Davis, handling and observing single molecules of DNA, shows how it's done...

Guideline For Brain Metastases Developed By ASTRO

Fri, 10 Feb 2012 01:00:00 PST

The American Society for Radiation Oncology (ASTRO) has developed a guideline on the radiotherapeutic and surgical management for newly diagnosed brain metastases. It has been published in Practical Radiation Oncology (PRO), ASTRO's official clinical practice journal...

Fasting May Boost Chemo By Weakening Cancer Cells

Fri, 10 Feb 2012 01:00:00 PST

Fasting was as effective as chemotherapy in delaying growth of specific tumors in mice and boosted the effectiveness of chemotherapy on melanoma, glioma, and breast cancer cells...

Similarities Between Genetic Signatures In Developing Organs And Breast Cancer Could Predict And Personalize Cancer Therapies

Fri, 10 Feb 2012 00:00:00 PST

Reviving a theory first proposed in the late 1800s that the development of organs in the normal embryo and the development of cancers are related, scientists at the Salk Institute for Biological Studies have studied organ development in mice to unravel how breast cancers, and perhaps other cancers, develop in people...

Identifying Cancer Cells For Immune System Attack With DNA Sequencing

Fri, 10 Feb 2012 00:00:00 PST

DNA sequences from tumor cells can be used to direct the immune system to attack cancer, according to scientists at Washington University School of Medicine in St. Louis. The research, in mice, appears online in Nature. The immune system relies on an intricate network of alarm bells, targets and safety brakes to determine when and what to attack...

CD97 Gene Expression And Function Correlate With WT1 Protein Expression And Glioma Invasiveness

Thu, 09 Feb 2012 00:00:00 PST

Researchers at Virginia Commonwealth University Medical Center's VCU Massey Cancer Center and Harold F...

Key Finding In Stem Cell Self-Renewal

Wed, 08 Feb 2012 01:00:00 PST

A University of Minnesota-led research team has proposed a mechanism for the control of whether embryonic stem cells continue to proliferate and stay stem cells, or differentiate into adult cells like brain, liver or skin. The work has implications in two areas. In cancer treatment, it is desirable to inhibit cell proliferation...

Early Signs Of Disease Detected By Metabolic 'Breathalyzer'

Wed, 08 Feb 2012 01:00:00 PST

The future of disease diagnosis may lie in a "breathalyzer"-like technology currently under development at the University of Wisconsin-Madison. New research published online in February in the peer-reviewed journal Metabolism demonstrates a simple but sensitive method that can distinguish normal and disease-state glucose metabolism by a quick assay of blood or exhaled air...

For Personalizing Cancer Therapy, Metabolic Profiles Are Essential

Wed, 08 Feb 2012 01:00:00 PST

One way to tackle a tumor is to take aim at the metabolic reactions that fuel their growth. But a report in the February Cell Metabolism, a Cell Press Publication, shows that one metabolism-targeted cancer therapy will not fit all. That means that metabolic profiling will be essential for defining each cancer and choosing the best treatment accordingly, the researchers say...

Zinc Control Mechanisms Could Be Key To Aggressive Breast Cancer Treatments

Wed, 08 Feb 2012 00:00:00 PST

The body's control mechanisms for delivering zinc to cells could be key to improving treatment for some types of aggressive breast cancer. New research by Cardiff University and King's College London has identified the switch which releases zinc into cells, with important implications for a number of diseases. Zinc has long been known to play a vital part in human health...

Patient Sensitivity To Important Drug Target In Deadly Brain Cancer Predicted

Wed, 08 Feb 2012 00:00:00 PST

A recent discovery by Van Andel Research Institute (VARI) scientists enables the prediction of patient sensitivity to proposed drug therapies for glioblastoma - the most common and most aggressive malignant brain tumor in humans...

News From The Journal Of Clinical Investigation: Feb. 6, 2012

Tue, 07 Feb 2012 02:00:00 PST

IMMUNOLOGY: How a stomach-colonizing bacterium protects against asthma The bacterium Helicobacter pylori can be found colonizing the stomach lining of almost half the world's population. Although persistent infection with Helicobacter pylori increases an individual's risk of developing stomach cancer, it also decreases their risk of developing asthma...

More Accurate Diagnosis Of Genetic Mutations Expected Using New Virtual Tool

Tue, 07 Feb 2012 01:00:00 PST

DNA sequencing to detect genetic mutations can aid in the diagnosis and selection of treatment for cancer. Current methods of testing DNA samples, Sanger sequencing and pyrosequencing, occasionally produce complex results that can be difficult or impossible to interpret...

Increased Risk Of Fatal Side Effects From 3 'Targeted' Cancer Drugs

Tue, 07 Feb 2012 01:00:00 PST

Treatment with three relatively new "targeted" cancer drugs has been linked to a slightly elevated chance of fatal side effects, according to a new analysis led by scientists at Dana-Farber Cancer Institute. They added that the risk remains low, but should be taken into account by physicians and patients. The incidence of fatal complications was 1...

Silver Compounds Found To Be Toxic To Cancer

Tue, 07 Feb 2012 00:00:00 PST

The internet is awash with stories of how silver can be used to treat cancer. Now, lab tests have shown that it is as effective as the leading chemotherapy drug - and may have fewer side-effects...

Brain Tumor Eradication And Prolonged Survival

Mon, 06 Feb 2012 01:00:00 PST

Tocagen Inc. has announced the publication of data showing the company's investigational treatment for high grade glioma eradicates brain tumors and provides a dramatic survival benefit in mouse models of glioblastoma...

Scientists Prove Multiple DNA Repair Defect In Monocytes

Mon, 06 Feb 2012 00:00:00 PST

Scientists working with Professor Bernd Kaina of the Institute of Toxicology at the Medical Center of Johannes Gutenberg University Mainz have demonstrated for the first time that certain cells circulating in human blood - so-called monocytes - are extremely sensitive to reactive oxygen species (ROS)...

New Hope For Patients With Deadly Brain Tumor

Mon, 06 Feb 2012 00:00:00 PST

Jim Black is fighting the meanest, most aggressive, most common kind of brain tumor in the United States: recurrent glioblastoma multiforme (GBM). In the United States, each year, approximately 10,000 patients are affected by GBM. Now, a novel investigational device - available only at clinical trial sites - is offering new hope to these patients...

Probable Mechanism Underlying Resveratrol Activity Revealed By NIH Study

Sun, 05 Feb 2012 00:00:00 PST

National Institutes of Health researchers and their colleagues have identified how resveratrol, a naturally occurring chemical found in red wine and other plant products, may confer its health benefits. The authors present evidence that resveratrol does not directly activate sirtuin 1, a protein associated with aging...

Six-Organ Transplant Girl Goes Home Today

Fri, 03 Feb 2012 10:00:00 PST

After 100 days in hospital and undergoing a complicated 6-organ transplant, 9-year-old Alannah Shevenell, from Maine, leaves Boston Children's Hospital today and goes home. Alannah has been treated for a rare form of cancer; an inflammatory myofibroblastic tumor continued to grow after all possible treatments failed, and was compromising her internal organs. A team of surgeons, led by Dr...

Device Provides A Platform For Viewing Cancer Cells And Other Macromolecules In Dynamic, Life-Sustaining Liquid Environments

Fri, 03 Feb 2012 01:00:00 PST

A photograph of a polar bear in captivity, no matter how sharp the resolution, can never reveal as much about behavior as footage of that polar bear in its natural habitat. The behavior of cells and molecules can prove even more elusive...

Chaos In The Cell's Command Center

Fri, 03 Feb 2012 00:00:00 PST

A defective operating system is never a good thing. Like computers, our cells depend on operating systems to drive normal functions. Gene expression programs comprise the software code our cells rely on, with each cell type controlled by its own program. Corrupted programs can trigger disease...

For Brain Cancer - A Thought-Provoking New Therapeutic Target?

Fri, 03 Feb 2012 00:00:00 PST

Glioblastoma multiforme (GBM) is the most common of all malignant brain tumors that originate in the brain. Patients with GBM have a poor prognosis because it is a highly aggressive form of cancer that is commonly resistant to current therapies. New therapeutic approaches are therefore much needed...

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