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Research highlights from the current issue of Science Magazine



Published: 2016-09-29T14:34:04-04:00

 



[Galactic Structure] Mapping the local Milky Way

2016-09-30

The spiral structures of far-away galaxies are among the most familiar celestial features. Viewed from within, the structure of our own Milky Way galaxy is harder to appreciate. Interstellar – [Read More]



[Signaling] Organ cross-talk for insulin secretion

2016-09-30

Organisms must adapt their growth to changing environmental conditions, such as variations in nutrient access. In Drosophila, dietary amino acids promote the release of insulin-like – [Read More]



[HIV-1 Vaccines] On the path toward a vaccine

2016-09-30

A major goal in combating HIV-1 is the development of a vaccine that can elicit broadly neutralizing antibodies (bNAbs). As bNAbs develop, however, they acquire many somatic mutations, – [Read More]



[Graphene] Recreating optics in graphene

2016-09-30

Light usually takes the shortest path to propagate between two points. In contrast, electrons in solids experience collisions. To get into a regime that resembles the propagation of – [Read More]



[Gene Regulation] Repairing the breaks you make

2016-09-30

Cyclin A2 is a mammalian cell cycle protein that plays a critical role in DNA replication and mitotic entry. It has been associated with poor clinical outcomes in human tumors. Kanakkanthara – [Read More]



[Geophysics] Rock deformation goes magnetic

2016-09-30

The topography in regions such as the western United States depends on the strength of the crust and lithosphere. To better understand regional tectonic–scale topographic evolution, L – [Read More]



[Additive Manufacture] More function with 3D printing

2016-09-30

The creation of parts by the guided layer-by-layer deposition of materials, better known as three-dimensional (3D) printing, is often confined to a single material. This can limit the – [Read More]



[Enhancer Function] CRISPR editing illuminates function

2016-09-30

The noncoding regions around a gene tend to control the transcription of protein-coding genes, but the specific elements involved are difficult to determine. Leveraging the editing – [Read More]



[Cancer Immunology] Engineering antitumor activity

2016-09-30

Dendritic cells present antigens, including those from tumor cells, to T cells to stimulate immune responses. Antitumor vaccines based on injecting dendritic cells, however, have not – [Read More]



[Neurodegeneration] Receptor propagates protein aggregation

2016-09-30

The protein α-synuclein, which is abundant in brain neurons, functions as a soluble monomer. Abnormal oligomerization of this protein into insoluble aggregates correlates with Parkinson's – [Read More]



[Cancer] A histone brake on tumor growth

2016-09-30

Individual tumors consist of a diverse collection of cells with different propensities to grow uncontrollably. This heterogeneity is often associated with the degree of differentiation – [Read More]



[Protoplanetary Disks] Spiral arms in a disk around a young star

2016-09-30

A disk of gas and dust orbits around young stars as they form. Eventually, planets can form in such disks. Perez et al. used submillimeter interferometry to observe the protoplanetary – [Read More]



[Biodiversity] Patterns of global genetic diversity

2016-09-30

Mapping of global biodiversity has been focused mainly at the species level; the distribution of underlying genetic diversity is less well documented. Miraldo et al. attach – [Read More]



[HIV-1 Infection] Progression at a standstill

2016-09-30

Although most people that become infected with HIV-1 develop AIDS, rare individuals maintain immune function in the presence of virus. This phenomenon is also seen in natural hosts – [Read More]



[Virology] Modeling hepatitis A in mice

2016-09-30

Although viral hepatitis is a major cause of morbidity worldwide, scientists lack good small-animal models for studying it, especially models that recapitulate virus-caused liver pathology. – [Read More]



[Social Memory] Sites and circuits to recognize friends

2016-09-30

The ability to recognize and memorize familiar conspecifics is crucial for all social animals. Okuyama et al. found that the ventral hippocampus and its projections to a brain – [Read More]



[Cognition] Bees have good moods, too

2016-09-30

Mood can influence our impression of ambiguous stimuli. Perry et al. show that such emotional-state biases are present in bumblebees, a finding that greatly increases the breadth – [Read More]