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Research highlights from the current issue of Science Magazine

Published: 2017-02-16T15:51:02-05:00


[Planetary Science] Organic compounds detected on Ceres


Water and organic molecules were delivered to the early Earth by the impacts of comets and asteroids. De Sanctis et al. examined infrared spectra taken by the Dawn spacecraft – [Read More]

[Infectious Disease] Hypoxic conditioning of immune cells


Oxygen deficiency, or hypoxia, alters immune cell function. How these hypoxia-induced immune cell changes affect the host response to bacterial infection has been unclear. Thompson – [Read More]

[Bacterial Division] Coordinating cell wall synthesis and cell division


Most bacteria are protected by peptidoglycan cell walls, which must be remodeled to split the cell. Cell division requires the tubulin homolog FtsZ, a highly conserved cytoskeletal – [Read More]

[High-Pressure Physics] Stamping hydrogen into metal


In 1935, Wigner and Huntington predicted that molecular hydrogen would become an atomic metal at a pressure of 25 GPa. Eighty years and more than 400 GPa later, Dias and Silvera have – [Read More]

[Physiology] Sugar rush


Flying requires high levels of energy production, which causes muscular oxidative damage. Food-derived antioxidants can protect against such damage; however, nectar is devoid of these – [Read More]

[Mutation Detection] When is a mutation a true genetic variant?


Large-scale sequencing studies have set out to determine the low-frequency pathogenic genetic variants in individu als and populations. However, Chen et al. demonstrate that – [Read More]

[Glaucoma] Vitamin B3 protects mice from glaucoma


Glaucoma is the most common cause of age-related blindness in the United States. There is currently no cure, and once vision is lost, the condition is irreversible. Williams et – [Read More]

[Infection] Touchdown for gut pathogen virulence


Escherichia coli is transformed from a commensal organism into a pathogen by acquisition of genetic elements called pathogenicity islands (PAIs). Katsowich et al.[Read More]

[HIV] Peak HIV viremia pushes CD8+ T cells


HIV induces widespread immune dysfunction. Animal studies with simian immunodeficiency virus have suggested that early CD8+ T cell responses may reduce viral burden. Takata – [Read More]

[Cell Biology] Understanding insulin release


Insulin release takes place in two phases: a first rapid burst followed by a series of small exocytic bursts that coincide with pulsatile spikes in cytosolic Ca2+ levels. – [Read More]

[Plant Science] Host-pathogen point-counterpoint


The arms race between pathogen and host is a well-known phenomenon. Ma et al. have now identified how an enzymatically inactive protein can abet a pathogen's infectivity. The – [Read More]

[Photochemistry] Hydroamination gets a light push uphill


Hydroamination of olefins is a broadly useful method for making carbon-nitrogen bonds. However, when both the amine and the olefin have multiple alkyl substituents, the reaction can – [Read More]

[Regeneration] Hair follicles: Secret to prevent scars?


Although some animals easily regenerate limbs and heal broken flesh, mammals are generally not so gifted. Wounding can leave scars, which are characterized by a lack of hair follicles – [Read More]

[Solar Cells] Passivating traps in perovskites


Low-temperature processing of planar organic-inorganic perovskite solar cells made through solution processing would allow for simpler manufacturing and the use of flexible substrates. – [Read More]

[Infectious Diseases] Being selective in fighting infection


Antibiotic-resistant bacterial strains are increasingly found in healthy people who show no symptoms. As a result, they are more vulnerable to invasive infections that can be lethal. – [Read More]

[Antiviral Immunity] An encephalitis-boosting microRNA


Japanese encephalitis virus (JEV), which is related to the Zika and West Nile viruses, targets the central nervous system. The encephalitis induced by JEV inflicts neurological damage – [Read More]

[Coastal Ecosystems] Missing meadows fail to mop up microbes


Seagrass meadows, a prominent feature of most healthy coastal ecosystems, are often also associated with shallow coral reefs. Many plants have bioremediation qualities, and seagrasses, – [Read More]