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Research highlights from the current issue of Science Magazine

Published: 2016-09-29T14:34:04-04:00


[Galactic Structure] Mapping the local Milky Way


The spiral structures of far-away galaxies are among the most familiar celestial features. Viewed from within, the structure of our own Milky Way galaxy is harder to appreciate. Interstellar – [Read More]

[Signaling] Organ cross-talk for insulin secretion


Organisms must adapt their growth to changing environmental conditions, such as variations in nutrient access. In Drosophila, dietary amino acids promote the release of insulin-like – [Read More]

[HIV-1 Vaccines] On the path toward a vaccine


A major goal in combating HIV-1 is the development of a vaccine that can elicit broadly neutralizing antibodies (bNAbs). As bNAbs develop, however, they acquire many somatic mutations, – [Read More]

[Graphene] Recreating optics in graphene


Light usually takes the shortest path to propagate between two points. In contrast, electrons in solids experience collisions. To get into a regime that resembles the propagation of – [Read More]

[Gene Regulation] Repairing the breaks you make


Cyclin A2 is a mammalian cell cycle protein that plays a critical role in DNA replication and mitotic entry. It has been associated with poor clinical outcomes in human tumors. Kanakkanthara – [Read More]

[Geophysics] Rock deformation goes magnetic


The topography in regions such as the western United States depends on the strength of the crust and lithosphere. To better understand regional tectonic–scale topographic evolution, L – [Read More]

[Additive Manufacture] More function with 3D printing


The creation of parts by the guided layer-by-layer deposition of materials, better known as three-dimensional (3D) printing, is often confined to a single material. This can limit the – [Read More]

[Enhancer Function] CRISPR editing illuminates function


The noncoding regions around a gene tend to control the transcription of protein-coding genes, but the specific elements involved are difficult to determine. Leveraging the editing – [Read More]

[Cancer Immunology] Engineering antitumor activity


Dendritic cells present antigens, including those from tumor cells, to T cells to stimulate immune responses. Antitumor vaccines based on injecting dendritic cells, however, have not – [Read More]

[Neurodegeneration] Receptor propagates protein aggregation


The protein α-synuclein, which is abundant in brain neurons, functions as a soluble monomer. Abnormal oligomerization of this protein into insoluble aggregates correlates with Parkinson's – [Read More]

[Cancer] A histone brake on tumor growth


Individual tumors consist of a diverse collection of cells with different propensities to grow uncontrollably. This heterogeneity is often associated with the degree of differentiation – [Read More]

[Protoplanetary Disks] Spiral arms in a disk around a young star


A disk of gas and dust orbits around young stars as they form. Eventually, planets can form in such disks. Perez et al. used submillimeter interferometry to observe the protoplanetary – [Read More]

[Biodiversity] Patterns of global genetic diversity


Mapping of global biodiversity has been focused mainly at the species level; the distribution of underlying genetic diversity is less well documented. Miraldo et al. attach – [Read More]

[HIV-1 Infection] Progression at a standstill


Although most people that become infected with HIV-1 develop AIDS, rare individuals maintain immune function in the presence of virus. This phenomenon is also seen in natural hosts – [Read More]

[Virology] Modeling hepatitis A in mice


Although viral hepatitis is a major cause of morbidity worldwide, scientists lack good small-animal models for studying it, especially models that recapitulate virus-caused liver pathology. – [Read More]

[Social Memory] Sites and circuits to recognize friends


The ability to recognize and memorize familiar conspecifics is crucial for all social animals. Okuyama et al. found that the ventral hippocampus and its projections to a brain – [Read More]

[Cognition] Bees have good moods, too


Mood can influence our impression of ambiguous stimuli. Perry et al. show that such emotional-state biases are present in bumblebees, a finding that greatly increases the breadth – [Read More]